LOCUS       NZ_JABBWV010000001     21071 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H11081 NODE_1, whole genome shotgun sequence.
ACCESSION   NZ_JABBWV010000001
VERSION     NZ_JABBWV010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H11081
  ORGANISM  Microbispora sp. H11081
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 1221004)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1221004)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Anotibioctics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012999535.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 06:41:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,738
            CDSs (total)                      :: 6,662
            Genes (coding)                    :: 6,604
            CDSs (with protein)               :: 6,604
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1 (5S, 16S)
            partial rRNAs                     :: 1, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 7 of 58
            Pseudo Genes (incomplete)         :: 54 of 58
            Pseudo Genes (internal stop)      :: 2 of 58
            Pseudo Genes (multiple problems)  :: 5 of 58
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:04:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 649287
            Orig. end                         :: 670358
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBWV010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21071
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21071
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21071
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11071](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11071)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    751..767
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.46"
                     /tool="antismash"
     misc_feature    complement(751..767)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.11"
                     /tool="antismash"
     gene            900..2189
                     /gene="allB"
                     /locus_tag="HHX31_RS02875"
     CDS             900..2189
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891412.1"
                     /locus_tag="HHX31_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allantoinase AllB"
                     /protein_id="WP_311931278.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.8e-26, bitscore:
                     89.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSRRTVTPEGERPLSVAVHDGVIAALAPYDEPPAAARHADLGDL
                     PLLPGLVDSHVHVNEPGRTHWEGFATATRAAAAGGVTTIVDMPLNSLPPTVDVAALEVK
                     RKAAEGRCHVDVAFWGGAIPGNLAHLRPLHEAGVAGVKCFLSPSGVDEFPALDREGLRA
                     ALAEVAAFDGLLIAHAEDPGLLSDPGGPAYGDFLRSRPQEAERAAVETVITLAAETGAR
                     AHIVHVSAAACVEPLRAAQAAGVRVTAETCPHYLTLAAEQVTGPAYKCCPPIREAANRD
                     ALWRALADGVLIGVVSDHSPSTPDLKVPDFAAAWGGISSLQVGLPAVWTAARARGHDLA
                     DVARWMAGGPARLAGLPRKGAIRVGNDADLVAFDPDAEFTVDVAALHHRNPVSPYHGAR
                     LAGVVRTTWLRGVPVDFGVPRGRLLTRGAR"
     gene            2186..3151
                     /gene="alc"
                     /locus_tag="HHX31_RS02880"
     CDS             2186..3151
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541667.1"
                     /locus_tag="HHX31_RS02880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allantoicase"
                     /protein_id="WP_169944697.1"
                     /transl_table=11
                     /translation="MTGFTRLPDLALRTYGGSVVAANDESFAEREALIRPGRAEFRPHT
                     FGAKGQVYDGWETRRRREPGHDWAIVRLGLPGVIRGVVVDTAWFRGNYPPYASVEACEA
                     EGHPAPDELDGWVEIVPKSPLKGDAVHEFAVTDPRRFTHVRLNIFPDGGVARLRVHGRV
                     VPDRAFLDGLTVDLAALENGGLVTACSDEFYSAPNNVLAPGLARDQSEGWETARRRDGG
                     NDWLVVALAGPGRVAVAEIDTTNLIFNAPGAASLTGADADRAPLEDPESWFPLLPRTRL
                     QPDTRHRFRLDDDRRVTHVRLDIHPDGGLARLRLLGALIP"
     gene            complement(3169..5151)
                     /gene="pknB"
                     /locus_tag="HHX31_RS02885"
     CDS             complement(3169..5151)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889483.1"
                     /locus_tag="HHX31_RS02885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_169944698.1"
                     /sec_met_domain="Pkinase (E-value: 6.7e-54, bitscore:
                     178.9, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 8.5e-08, bitscore: 28.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLTDPLVGQLLDGRYRVESRIARGGMASVYLALDVRLDRTVA
                     VKVMHRSLAEDPQFVRRFIGEAKSVASLSHPNIVQVFDQGTDGANVYLSMEYVPGRTLR
                     DVLRARGRLPAREALEMVIPVLAALGAAHQAGLVHRDVKPENVLLADDGRVKVVDFGLA
                     RAIEATNQTKTGMMIGTIGYMSPEQVTTGNADARSDVYAAGIMLFELLTGRQPYAGETP
                     MSVAYRHVHETVPMPSSIVPDVPPSIDALVAAATDKDPAARPADATAMLVASVEIHRTL
                     PRTGHTGAHAAPHGVHDSGAHSGVRTGAHRTLPPPGGASPFGSGQHARPEAGQTMIQPR
                     PELPADAPRRRRRAGVRPVWFVAALALVMVAGVAFTGWWFSQGRYMTVPDLVGQNLTVA
                     RQEAQKAGFEVRVGKARFDDKAPKDIILDTEPGAGAEVVKGSVLTLIPSAGPETIPVPK
                     VEGLSLADARAKIAEAGLTPGRVSKSASDTVPRDQVIRTNPPVGKRVKKRGAVNFVVSA
                     GLLMPDVTQMMRDQAEKFLRDKGFQVQVDETTDDAPPGTVIAQDPSGGAEVVAGATVRL
                     TASRGPDQGFRWPWETDPADPDGGPPPTVVEVPNVMFKSVNDAVNELKRAGFKVNVRKV
                     VGTDRVVGEKPLGQQPPGTTITIWH"
     gene            complement(5346..6110)
                     /locus_tag="HHX31_RS02890"
     CDS             complement(5346..6110)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018658554.1"
                     /locus_tag="HHX31_RS02890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazole synthase"
                     /protein_id="WP_169944700.1"
                     /transl_table=11
                     /translation="MTDDVFVLGGEKFASRLIMGTGGAPSLEVLDQALEASGTELTTVA
                     MRRLDPAARGSVLDVLRARGIKVLPNTAGCFTAGEAVLTARLAREALETDWVKLEVIAD
                     ERTLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLQDAGCAAVMPLGAPIGSGLG
                     IRNPHSIELIVEAATVPVILDAGIGTASDAALAMELGCDAVLLASAVTRAHRPDLMASA
                     MRQAVTAGRQARLAGRIPRRRHAEASSPGRPF"
     gene            complement(6113..6313)
                     /gene="thiS"
                     /locus_tag="HHX31_RS02895"
     CDS             complement(6113..6313)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131590.1"
                     /locus_tag="HHX31_RS02895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_169944701.1"
                     /transl_table=11
                     /translation="MKVTINGGAAELSDGATVGDAVRTLTSLASGVAVALNGEVVSRST
                     WDSTPVADGDDVEVLTAVQGG"
     gene            complement(6310..7422)
                     /gene="thiO"
                     /locus_tag="HHX31_RS02900"
     CDS             complement(6310..7422)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889486.1"
                     /locus_tag="HHX31_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_169944702.1"
                     /sec_met_domain="DAO (E-value: 6.2e-70, bitscore: 232.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPAYDVVIAGGGVAGLAVAWRAARRGLSVAVADPTPGGGATHAS
                     AGMLAPVSEVTYTEEPLLRLGLASLAAWPAFRAALEDESGIELDYRTDGTLEVARSADD
                     MAFLDDLAAFERTLGLRVERLTGRECRSFEPMLAPSVRGGLLARDDAWVNPRRVVRALL
                     TAFEKAGGVLVSEHVAEIGASGTGGPSVRLTNGDTVPAGQVVVAAGSWSASLLPGLPVR
                     PVKGEILRLRGPQGFLTRCVRGLVHGSPAYLVPRGDGEITLGATVQELGHDERVTAGGV
                     YELLRDARELVPGITELELAETTVGFRPGTPDNLPIIGPAGPPGVFAATGHGRNGVLLC
                     PITADAVAAFLTGDEPPQVIGSCHPGRFSQ"
     regulatory      complement(7413..7523)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    7685..7705
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            7698..8876
                     /locus_tag="HHX31_RS02905"
     CDS             7698..8876
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889487.1"
                     /locus_tag="HHX31_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_169944704.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.9e-54, bitscore:
                     179.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHVVVVGAGLAGVRSIEALRACGFTGRVTLIGEEHHRPYDRPPL
                     SKAVLLGETDSTVVDSDLDALDVRLCLGTAAKGLRDGVLETTEGELEYDGLVIATGATP
                     IRLRGEGRQHVLRTIEDALALRERLVPGARVAVVGAGWIGAEVATAAARAGCAVTVVEA
                     GESPLAMALGPEVGSHTIGWYARAGVELRLGAMVGTVDADGLTLMSGARVPADVVVTGV
                     GVRPAVDWLKGSGVRLDDGVVVDEHLRTSLPGVVAVGDCASWWSRRFGTRLRVEHWDTA
                     LQAPDTAVATLLGEEAVYDPVPYFWSEQFGHMVQFAGHREAGDRVLRRGDPRTDAKWAV
                     CWLTADDRLAAVLTVDRPRDVVQGRRIVEGGQRLDPRRVADPAVPLRDCIMA"
     gene            8920..9294
                     /locus_tag="HHX31_RS02910"
     CDS             8920..9294
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131593.1"
                     /locus_tag="HHX31_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_169944705.1"
                     /transl_table=11
                     /translation="MTLTVAQIDRKTDELVGEWLPLSDAAKRLGLSIGRAKQLLKDKKL
                     AGVRRGGGEPQIPAVFIAGGEVLKGLPGTLTLLADAGYDEVESIRWLFTPDDSLPGSPI
                     DAILKGRHTEVKRRAQALGF"
     gene            9325..9978
                     /gene="thiE"
                     /locus_tag="HHX31_RS02915"
     CDS             9325..9978
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131594.1"
                     /locus_tag="HHX31_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_169944707.1"
                     /transl_table=11
                     /translation="MTDTRRQRLAQARLYLCTDGRRDRGDLEKFLDAVLSGGVDIVQLR
                     EKGLEAREELELLQVFRAACDRHGALLAVNDRADVAFAAGPDILHLGQDDLPVPVAREI
                     LGSGVLIGRSTHSAAEASAAAVEPGVDYFCCGPIWPTPTKPGRPAPGPVLLDHAARLGD
                     GRPWFGIGGIDLGNLDEVMAHGVRRAVVVRAITEADDPGAAAAALKARLSTVPL"
     gene            complement(10001..11071)
                     /locus_tag="HHX31_RS02920"
     CDS             complement(10001..11071)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131595.1"
                     /locus_tag="HHX31_RS02920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_169944708.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-48, bitscore:
                     161.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASAVSLDSIRTEVDRALREFIDRQRPHFGDPHLAAILTAAEDF
                     LAGGKRLRPAFCHWGWRAGGGDAHDPGLNAAAASLELLQASALIHDDVMDASDVRRGMP
                     SAHRRFERIHAEAGWHGSAEQFGEGSAVLLGNLLLVWSGEMWRTCGLAPEALAAAQPVH
                     DHMLTELMCGQYLDLLEQAQGESTHDSALRVALYKSGKYSVEQPLRLGLVLAARARHSW
                     IDRLCVQYGQQVGIAFQLRDDILGVFGDPAETGKPAGDDLREGKRTVLIARALADATPA
                     QAGVVRSLLGDPELDADGVGRLRAVIEDTGALAACEGMIKRYLDDALLALDHAPIEEEA
                     RAALAALAVAATARRT"
     misc_feature    complement(11115..11132)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            11212..12138
                     /gene="metF"
                     /locus_tag="HHX31_RS02925"
     CDS             11212..12138
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131596.1"
                     /locus_tag="HHX31_RS02925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_169944710.1"
                     /transl_table=11
                     /translation="MALGLPSRLPDRVPTVRELLAAGERSFSFEFFPPKTDEGERQLWR
                     AIRELEALRPTFVSVTYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHL
                     VGRFADAGVRNILAVRGDPRGGNPLDEWVKHPEGVLYAEDLVRLIRQAGDFCVGVAAFP
                     YKHPRSATIESDTKYFVQKCRAGADYAITQMFFRAEDYLRLRDRVAAHGCDTPIIPGIM
                     PVTQMSTIARSEQLSGAPFPREVAERFEAVADDPAAVRRVGIEHAVELCQKLLDEGAPG
                     IHFITFNRSSATREVFQALHSVPAVAG"
     gene            complement(12160..12732)
                     /locus_tag="HHX31_RS02930"
     CDS             complement(12160..12732)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617048.1"
                     /locus_tag="HHX31_RS02930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_169944712.1"
                     /transl_table=11
                     /translation="MIQLRRVGPDRFRAVLDTVLEIYTVAMRPPSDQLAGRLAIMRNHS
                     TYPEFDCLLAEDAQAPGGVAGFAYGFHGGRGQWWHDVVRGALQDRAGPVAAEDWFGDAL
                     EIAEIHVRPEYQGQGVGRRLIHALCEGRPERTAVLSTHDAPTVARHLYRDVGFTDLMTR
                     FVFPGGYEEYVIAGVRLPLPELDARRD"
     gene            complement(12777..13253)
                     /locus_tag="HHX31_RS02935"
     CDS             complement(12777..13253)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="HHX31_RS02935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_169944714.1"
                     /transl_table=11
                     /translation="MAEKLHPNVIRVQEALRALEATGEVVVLDEAAPTAATAAARLGCE
                     VGAIANSLIFDADGAPLLVLTSGAHRVDTDLIARVAGAAKVRRATPEFVREHTGQPIGG
                     VAPVGHPAPVRTLVDTWLSKHDVVWAAAGHPHTVFPTSYEELLRITGGTATDVA"
     misc_feature    13236..13252
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     gene            13379..14302
                     /locus_tag="HHX31_RS02940"
     CDS             13379..14302
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541679.1"
                     /locus_tag="HHX31_RS02940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_249345350.1"
                     /transl_table=11
                     /translation="MMRGRRRLAAATLVAVGAVAFGATGVTGTALARTAAPTGTLTTGT
                     LTTGTLTTGTLTTGTVRSALPALPALPALPALPARGAVPASAAAYPPFAAPGKTLKLGA
                     KGSAVKALQSRLKELGYMPGSADGRYGGTTQAAVWAFQKVQGIAPTSTIAARTWRALEN
                     PRAPRVLVPRGRPTRVEVDLTRQVMVLYRGGAPVLISHISSGSGIPYTEYAIWNGKRQR
                     FSGSARTPTGDYRTTWRVKGWHRSYLGQLYNPIFFNGGIALHGALSVPLYPASHGCVRL
                     PMNVAEVLPGMLGKGVPVHVRGAFRR"
     misc_feature    complement(14363..14379)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.05"
                     /tool="antismash"
     misc_feature    complement(14386..14401)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.19"
                     /tool="antismash"
     misc_feature    14387..14400
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.72"
                     /tool="antismash"
     misc_feature    14388..14399
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.53"
                     /tool="antismash"
     misc_feature    14426..14441
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.49"
                     /tool="antismash"
     misc_feature    complement(14427..14440)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.0"
                     /tool="antismash"
     gene            14710..15147
                     /locus_tag="HHX31_RS02945"
     CDS             14710..15147
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131600.1"
                     /locus_tag="HHX31_RS02945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_169944716.1"
                     /transl_table=11
                     /translation="MTEQNDDQRGGPRLSQAVLAHLADARACLADATVGPTPADRYVSA
                     HLAALRAAAGILAARPRPMDGRRRRLRSAWELLPEAEPKLADWAAYFAVSATKRAAAEA
                     GMVRAVTQHDAEEIIAEADRFVGEVESILGLPGRPTLPMAG"
     gene            complement(15334..16578)
                     /locus_tag="HHX31_RS02950"
     CDS             complement(15334..16578)
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889503.1"
                     /locus_tag="HHX31_RS02950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arginine deiminase"
                     /protein_id="WP_169944718.1"
                     /transl_table=11
                     /translation="MTFFVGSEVGRLRQVLVDIPELALKRLTPGNKDGLLFDDVLWVHR
                     ALEEHREWCEVLTGHGVTVHRLGDLLREVIEIPDARKHILDGSVDEHWFGPLAADAIRN
                     TLDSLDADALAPLLTGGITKREIMELGCDPGSIVFHTLGTDDFVLPPLPNHLFARDTSC
                     WVYDGVSINAMRKKARRRETVNYEAVYRWHPLFAAGYAKPDDGGFNVWYEGVRMAPATI
                     EGGDVLVLGGGVVLVGVSERTQPQAVEMLATNLFRAGSATRIVALDLPKARAFMHLDTV
                     MTNVDVGVFTKYAGLGMLPSYTVEPGDTEKELKVTDHPPEDMHKAIARALGLDDIKVLT
                     PTQDVHAAEREQWDDGCNVLALEPGVVVAYERNTTTNNYLRRHGIEVIPIRGSELGRGR
                     GGPRCMSCPLERDPV"
     gene            complement(16714..17208)
                     /locus_tag="HHX31_RS02955"
     CDS             complement(16714..17208)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="HHX31_RS02955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator"
                     /protein_id="WP_030508976.1"
                     /transl_table=11
                     /translation="MPSDYAKSLGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLAPAPKLVIDLERLSQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPVELTEEFIHWGVLDAEARRAVES
                     F"
     misc_feature    complement(17403..17418)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     misc_feature    17643..17652
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            17653..18210
                     /gene="pyrR"
                     /locus_tag="HHX31_RS02960"
     CDS             17653..18210
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889507.1"
                     /locus_tag="HHX31_RS02960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_169944720.1"
                     /transl_table=11
                     /translation="MSDARNPARAVLEGPDIHRALTRIAHEILERTRGAESVVLIGIPT
                     RGATLAQRIAERIAQFEGIKVPVGAIDVTMYRDDLRLRPARPLGRTELPADGVDGRTVV
                     LVDDVLYSGRTVRAALDALNDVGRPRAVQLATLVDRGHRELPIRADYVGKNLPTSKSEK
                     VKVFLEETDGRDAVVLIKEGDR"
     gene            18207..19142
                     /locus_tag="HHX31_RS02965"
     CDS             18207..19142
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131603.1"
                     /locus_tag="HHX31_RS02965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_169944722.1"
                     /transl_table=11
                     /translation="MKRHLISTGDLTRDDALLILDTAEELARVSQRSIKKLPTLRGRTV
                     VNLFFEDSTRTRISFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGADAVVI
                     RHSASGAPHRLASWVRGSVVNAGDGTHEHPTQALLDAFSIRRRLGRLEGLKIAIVGDVL
                     HSRVARSNVLLLHTLGAEVTLVAPPTLLPVAVGTWPCQVSYDLDAVLPKSDVVMMLRVQ
                     LERMNAAYFPSAREYSRRYGLDRDRFARLHDDAIVMHPGPMNRGMEISAEVADSPRSTI
                     VEQVANGVTVRMAVLYLLLGGSEPAIGGAE"
     gene            19139..20473
                     /locus_tag="HHX31_RS02970"
     CDS             19139..20473
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131604.1"
                     /locus_tag="HHX31_RS02970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydroorotase"
                     /protein_id="WP_211589168.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2e-16, bitscore:
                     56.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTYDFHEGTAVSTILIKGARILGGAPADILLRDGVVAETGDLAG
                     ARAGQTVDADGLVALPGLVDLHTHLREPGREDAETVETGTQAAARGGYTAVHAMANTSP
                     VADTAGVVEQVWRLGQACGHCDVQPVGAVTSGLEGRQLAELGAMADSAARVRVFSDDGK
                     CVSDAVLMRRALEYVKAFDGVVAQHAQEPRLTEGAQLNEGEVSARLGLTGWPAVAEEAI
                     IARDCLLAAHVGSRLHVCHVSTAGSVEIIRWAKSKGWDVTAEVTPHHLLLTDSCAETSP
                     LGPYNPLYKVNPPLRTADDVRALREALADGTIDCVATDHAPHPVEDKETEWGAAAMGMI
                     GLETALSVVQEAMVETGLLDWAGVADRMSVRPARIGRLAGHGRMIEPGAPANVTLYDPS
                     VRQHVDPSAMVSKSRNTPYEGLTLPGRVVATFLRGRPTVLEGKLV"
     misc_feature    21011..21031
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
ORIGIN
        1 ggcggcagcg cctgcaccga cgggggcgcg gggatggccc aggccctcgg cgtacggctg
       61 ctggacgcgg cgggcgacga cctgccgtac ggcggggccg cgctgcgcga cctccacacc
      121 gtcgacgcct cgggacggct gcgcgggttc gaggtgatcg tggcgagcga cgtggacaac
      181 ccgctgctcg ggccgtacgg cgcggcggcg gtgtacggcc cgcagaaggg cgcgagcccg
      241 caggacgtcg cggtgctcga ggccgggctg gcccggctgg cggccgtgac cgcgcacacc
      301 cacggcctgg cgggcgcggc cgagcacgac ggcgtggtcc gcgcgatggg cgtggccggg
      361 cggccggggg ccggcgccgc gggcggggtg gggttcggcg cgctgacgtt cctcgacgcg
      421 gagatcaggc ccggcatcgg ctacctgctc gacctcgtgg agttcgaccg gcacgtggcg
      481 ggcgcgcggc tggtcatcac gggcgagggc tcgatcgacg agcagaccct gcgcggcaag
      541 gccccggtgg gcgtcgccgc ggccgcggcc gagcatggcg tgccggtcgt ggcggtctgc
      601 ggcaggcggt cggtgggcga tgacgagttg cgggcggccg gcatagaggc ggcgtacgcg
      661 ctgaccgaca tcgagcccga cgtgagccgc tgcgtggcgg aggccgggcc gctgctggag
      721 aagctcgcgg cgcggatcgc cgccgagcgt ctggtgcaag atcacaaacg ggcgatgccc
      781 aggtcgtgag gggagtggcg agtttcgtgc atgatcacgg aggtgataac cgcaggtcag
      841 cggcatcgtc tgcgacaaac tacaagatca cgccgggtgg gggggtgtgg gatctggtgg
      901 tgcgatcacg gcggaccgtg accccggagg gggagcgccc tctctcggtc gccgtgcacg
      961 acggtgtgat cgccgccctg gccccctacg acgagccgcc cgcggccgcg aggcacgcag
     1021 acctcggcga cctgccgctg ctgcccgggc tggtcgactc ccacgtgcac gtcaacgagc
     1081 cgggccgcac ccactgggag ggcttcgcga ccgccaccag ggcggcggcg gccggaggcg
     1141 tgaccaccat cgtggacatg ccgctcaact cgctgccccc gaccgtggac gtggccgcgc
     1201 tggaggtcaa gcggaaggcc gccgaggggc ggtgccacgt ggacgtcgcc ttctggggcg
     1261 gtgcgatccc cggcaacctc gcccacctgc gccccctgca cgaggccggc gtggcgggcg
     1321 tcaagtgctt cctctcgccg tcgggcgtgg acgagttccc cgcgctcgac cgcgaggggc
     1381 tgcgggccgc gctcgcggag gtggcggcct tcgacggcct gctgatcgcc cacgccgagg
     1441 accccggcct gctgtcggac ccaggcggcc ccgcgtacgg cgacttcctc aggtcgcggc
     1501 cccaggaggc ggagcgcgcg gccgtcgaga cggtgattac gctcgcggcg gagacggggg
     1561 cgcgggcgca catcgtgcac gtgtcggccg ccgcctgcgt ggaaccgctg cgcgcggccc
     1621 aggcggcggg ggtgcgcgtc accgcggaga cctgccccca ctacctgacg ctggcggccg
     1681 agcaggtcac cgggcccgcc tacaagtgct gcccgccgat cagggaggcg gccaaccgcg
     1741 acgcgctgtg gcgggcgctc gccgacggcg tgctcattgg ggtcgtctcc gaccactccc
     1801 cgtcgacgcc cgacctcaag gtgcccgact tcgccgcggc ctggggcggg atctcctcgc
     1861 tccaggtcgg cctgcccgcc gtgtggacgg cggcccgtgc ccgcggccac gacctggccg
     1921 acgtggcgcg ctggatggcc gggggacccg cccgcctggc cggtctgccg cgcaaggggg
     1981 cgatccgggt gggcaacgac gcggacctgg tcgccttcga ccccgacgcc gagttcaccg
     2041 tcgacgtcgc ggcgctgcac caccgcaacc ccgtctcccc ctatcacggc gcgcggctcg
     2101 cgggcgtcgt gcgcaccacc tggctgcgcg gggtgccggt cgacttcggc gtcccgcgcg
     2161 gacgactgct gacccgagga gcgcgatgac cggcttcacc cgcctgcccg acctcgccct
     2221 gcgcacgtac ggcgggtcgg tcgtggccgc caacgacgag tcgttcgccg agcgggaggc
     2281 gctcatcagg ccgggaaggg ccgagttccg gccgcacacc ttcggcgcca agggccaggt
     2341 gtacgacggc tgggagacgc ggcgaaggcg tgagcccggc cacgactggg cgatcgtcag
     2401 gctcgggctg ccgggcgtca tcaggggcgt ggtggtggac accgcgtggt tccgcggcaa
     2461 ctacccgccg tacgcgtcgg tggaggcgtg cgaggccgag ggccatcccg cgccggacga
     2521 gctggacggc tgggtggaga tcgtgccgaa gagcccgctg aagggcgacg cggtccacga
     2581 gttcgcggtg accgacccgc gccgtttcac gcacgtgcgg ctgaacatct tccccgacgg
     2641 cggcgtggcg cggctgcggg tccacggccg ggtggtgccc gaccgcgcgt tcctcgacgg
     2701 cctcaccgtc gatctcgccg cgctggagaa cggcggcctg gtcactgcct gctccgacga
     2761 gttctactcc gcgccgaaca acgtcctcgc gcccggcctg gcccgcgacc agtccgaggg
     2821 ctgggagacc gcgcgccgcc gagacggcgg caacgactgg ctcgtcgtcg ccctggccgg
     2881 gccgggcagg gtggccgtcg ccgagatcga cacgacgaac ctgatcttca acgcccccgg
     2941 cgcggcgtcg ctgacgggcg cggacgcgga ccgggcgccg ctggaggacc cggagtcctg
     3001 gttcccgctg ctgccgagga cgcgcctgca gcccgacacc cgccaccgct tccgcctcga
     3061 cgacgaccgc agggtcacgc acgtccggct cgacatccac cccgacggcg ggctcgcccg
     3121 cctccggctc ctcggcgcgc tcatcccctg aacggccggg cgggggcgtc agtgccagat
     3181 cgtgatggtg gtgcccggcg gttgctggcc tagcggcttc tccccgacca cgcggtcggt
     3241 gcccaccacc ttgcggacgt tgaccttgaa accggccctc ttcagctcgt tcaccgcgtc
     3301 gttgacggac ttgaacatca cgttgggcac ctcgacgacg gtgggcgggg ggccgccgtc
     3361 ggggtcggcg gggtcggtct cccacggcca gcggaagccc tggtcgggcc cgcgagaggc
     3421 cgtaaggcgc acggtcgccc cggccaccac ctcggcgccg cctgaggggt cctgggcgat
     3481 caccgtgccg ggcggggcgt cgtcggtggt ctcgtcgacc tgcacctgga agcccttgtc
     3541 gcgcaggaac ttctccgcct ggtcgcgcat catctgcgtg acgtccggca tcagcagccc
     3601 cgcgctgacg acgaagttca ccgcgccgcg cttcttgacc cgcttgccca ccggcgggtt
     3661 ggtgcggatg acctggtcac gggggacggt gtcgctcgcg ctcttgctga ccctgccggg
     3721 ggtcagcccg gcctcggcga tcttcgcgcg ggcgtccgcc aggctgaggc cctccacctt
     3781 cggcacgggg atcgtctccg ggcccgccga cgggatcagg gtgaggacgg agcccttgac
     3841 cacctcggcg cccgcgccgg gctcggtgtc gaggatgatg tccttcggcg ccttgtcgtc
     3901 gaacctcgcc ttgccgaccc gcacctcgaa gccggccttc tgcgcctcct gcctggcgac
     3961 cgtgaggttc tgaccgacca ggtcggggac ggtcatgtag cgcccctggg agaaccacca
     4021 gccggtgaag gcgacgcccg cgaccatgac gagggcgagc gcggcgacga accacacggg
     4081 cctcaccccg gcccggcgcc gccggcgcgg cgcgtcggcc ggcagttccg ggcggggctg
     4141 gatcatcgtc tggccggcct cgggccgcgc gtgctggccc gagccgaacg gcgaggcccc
     4201 gccgggcgga gggagggtcc tgtgggcgcc cgtccgcacg ccgctgtgcg ccccgctgtc
     4261 gtggactccg tggggggcgg cgtgcgcgcc ggtgtgcccg gtccgcggca gcgtgcggtg
     4321 gatctcgacg gacgcgacga gcatggcggt cgcgtcggcc gggcgcgcgg ccgggtcctt
     4381 gtcggtggcg gcggcgacga gcgcgtcgat ggacggcggc acgtcgggca cgatcgagga
     4441 cggcatgggg acggtctcgt gcacgtgccg gtaggcgacc gacatcggcg tctcgcccgc
     4501 gtacggctgc cgcccggtca gcaactcgaa cagcatgatc ccggcggcgt acacgtcgct
     4561 gcgggcgtcg gcgttgccgg tcgtgacctg ctcgggcgac atgtagccga tcgtgccgat
     4621 catcatgccg gtcttggtct ggttggtcgc ctcgatcgcg cgggccaggc cgaagtccac
     4681 gaccttcacc cggccgtcgt cggcgagcag gacgttctcc ggcttgacgt cccggtggac
     4741 gagccccgcc tggtgggccg cgccgagggc ggcgagcacc gggatgacca tctccagcgc
     4801 ctcgcgcgcg ggaaggcggc cgcgggcgcg cagcacgtcg cgcagcgtcc tgccggggac
     4861 gtactccatc gacaggtaga cgttcgcccc gtccgtgccc tggtcgaaga cctgcacgat
     4921 gttggggtgc gagaggctcg ccaccgactt ggcctcgccg atgaaccgcc gcacgaactg
     4981 cgggtcctcc gcgagcgagc ggtgcatcac cttgacggcc accgtgcggt cgagccggac
     5041 gtccagggcc aggtagacgg aggccatgcc gccccgggcg atccgggact cgacgcggta
     5101 gcgcccgtcg agcaactgcc ccacgagcgg gtcggtcagc gtcgtgtcca ctcgccagag
     5161 tttacgggtg atttgccgct gggcgtgttc cctaatccca aaccgagacc tattcggcag
     5221 ccttccacgc cctcagaaaa gccatgccga atcagaaagc cgcgcttacc agacgtggac
     5281 tccgcgcctg tgcgcccacg ggcgcacagg cgcggacaag acactcgaag ggggcggcgg
     5341 ccggttcaga atgggcggcc gggggaggac gcctcggcgt ggcggcggcg ggggatcctg
     5401 cccgccaggc gggcctgccg cccggccgtg accgcctgcc gcatggccga ggccatcagg
     5461 tcaggccggt gcgcccgggt cacggcgctg gccagcagca cggcgtcgca gcccagctcc
     5521 atcgccagcg cggcgtcgct ggccgtgccg atgcctgcgt cgaggatcac cgggaccgtg
     5581 gcggcctcga cgatcagctc gatgctgtgc gggttgcgga tgcccagccc ggagccgatg
     5641 ggagcgccga gcggcatcac cgccgcgcac ccggcgtcct gcagcctgcg ggccagcgcc
     5701 gggtcgtcgc cgatgtacgg cagcacgacg aagccgtcgg cgaccaggcg ctcggcggcg
     5761 tcgaaggtct cgatcggatc gggcagcagg gtccgctcgt cggcgatgac ctccagcttg
     5821 acccagtcgg tctccagcgc ctcgcgggcc agacgggcgg tcagcaccgc ctcgcccgcc
     5881 gtgaagcacc ccgcggtgtt cggcagcacc ttgatgccgc gggcgcgcag cacgtccagc
     5941 acggaaccgc gcgccgccgg gtccagcctg cgcatggcga cggtggtcag ctcggtgccg
     6001 gacgcctcca gcgcctggtc tagcacctcc agggacggcg cgccgccggt gcccatgatg
     6061 agccgcgagg cgaacttctc cccgccgagc acgaagacgt cgtcggtcat ggtcatcctc
     6121 cctgcaccgc cgtcagcacc tcgacgtcgt cgccgtcggc caccggggtg gagtcccagg
     6181 tgctccggct caccacctcg ccgttcaggg ccaccgcgac cccggacgcg agggacgtga
     6241 gggtccgtac ggcgtcgccg accgtggcgc cgtcggacag ctcggccgct cctccgttga
     6301 tcgtgacttt cactggctga atctccctgg atgacaggat ccgatgacct ggggtggctc
     6361 gtctccggtg aggaacgccg cgacggcgtc ggcggtgatc gggcacagca gcacgccgtt
     6421 gcggccgtgc ccggtcgccg cgaacacgcc cggcggtccc gcggggccga tgatcggcag
     6481 gttgtcgggc gtgcctggcc ggaagccgac cgtggtctcg gccagttcga gctcggtgat
     6541 gccgggcacc agctcccggg cgtcgcgcag cagctcgtac acgccgccgg cggtgacccg
     6601 ctcgtcgtgc ccgagctcct gcaccgtggc gcccagcgtg atctctccgt cgcccctggg
     6661 caccagatag gcgggggagc cgtgcaccag cccccgtacg caccgcgtga ggaacccctg
     6721 gggcccgcgc agccggagga tctcgccctt gaccgggcgc accggcaggc cgggcaggag
     6781 ggacgccgac cacgacccgg ccgccacgac gacctggccc gccgggaccg tgtcgccgtt
     6841 cgtcagccgt acggacgggc caccggtgcc ggaggcgccg atctcggcga cgtgctcgga
     6901 gaccagcacg ccgcccgcct tctcgaacgc cgtgagcagg gcccgcacga ccctgcgggg
     6961 gttgacccag gcgtcgtcgc gggccagcag cccgccgcgc accgacgggg cgagcatcgg
     7021 ctcgaaggag cggcactcgc gcccggtgag ccgctcgacc cgcaggccga gcgtccgctc
     7081 gaaggccgcc aggtcgtcga ggaaggccat gtcgtccgcg ctcctggcga cctcgagcgt
     7141 gccgtcggtg cggtagtcca gctcgatgcc gctctcgtcc tccagcgcgg cgcggaacgc
     7201 cggccaggcc gcgagcgacg cgaggccgag ccgcagcagc ggctcctcgg tgtaggtcac
     7261 ctcgctgacc ggtgcgagca tcccggccga ggcgtgggtg gcgccgccac cgggcgtggg
     7321 gtccgccacc gcgaccgaca agccccggcg ggccgcgcgc caggccacgg cgaggcccgc
     7381 cacgccgccg ccggcgatca caacgtcgta tgcgggggac aaaccgcgct cccttcgccg
     7441 gcattacccg gatcaggtcg gggcggtcga gagcctcgcg ctctcctctc agcccggtcc
     7501 gccgggctcc cgcgcgtcgt acgcccacaa gcgtagtacg ccgcccgtcg cgaccgatcg
     7561 ccggatccgc ggccggtgtc aggcgagtca aggggccgct tcacaacgcg ggcccccgcg
     7621 gaagtgcgcg ctacttaccc aactcgttat gaggggcccg ttggccaggc cccccgctga
     7681 caatctatgg tcaaactgtg gatcacgtcg tggtggtggg tgccggcctg gccggcgtgc
     7741 ggagcatcga ggcgttgagg gcctgtgggt tcaccggccg cgtcacgctc atcggcgagg
     7801 aacaccatcg cccctatgac cgcccgccgc tgtcgaaggc ggtgctgctc ggagagaccg
     7861 actccacggt ggtcgactcg gacctcgacg ccctcgacgt acggctgtgc ctgggcacgg
     7921 cggccaaggg actgcgcgac ggcgtgctgg agacgaccga gggcgagctg gagtacgacg
     7981 gcctggtcat cgccaccggc gccaccccga tccggctgcg cggcgagggc cgccagcatg
     8041 tgctgcggac catagaggac gcgctggcgt tgcgcgagcg gctggtcccc ggggcccggg
     8101 tggccgtggt gggggccggc tggatcggcg ccgaggtcgc caccgccgcg gccagggccg
     8161 ggtgcgccgt gaccgtcgtg gaggcggggg agagcccgct cgccatggcg ctcggcccgg
     8221 aggtcggcag ccacaccatc ggctggtacg cgcgggcggg cgtcgagctg cgtctcggcg
     8281 cgatggtcgg cacggtggac gccgacggcc tcacgctcat gtccggcgcg cgggtgccgg
     8341 cggacgtggt cgtcaccggc gtcggggtgc gcccggccgt cgactggctg aagggctcgg
     8401 gcgtccggct cgacgacggg gtcgtggtcg acgagcacct gcgcacgtcg ttgcccggcg
     8461 tggtcgcggt gggcgactgc gcgagctggt ggtcgcgcag gttcggcacc cggctgcggg
     8521 tggagcactg ggacaccgcg ctccaggcgc cggacacggc cgtcgccacc ctcctgggcg
     8581 aggaggcggt ctacgacccg gtgccgtact tctggtcgga gcagttcggt cacatggtgc
     8641 agttcgccgg gcaccgtgag gccggtgacc gggtgctgcg gcgcggcgac ccgcgtacgg
     8701 acgcgaagtg ggcggtgtgc tggctgaccg ccgacgacag gctcgccgcg gtgctcaccg
     8761 tggaccggcc gcgcgacgtc gtgcagggcc gccggatcgt cgagggcggc cagcggctcg
     8821 acccgcggag ggtggcggat cccgccgtcc cgctccgcga ctgcattatg gcgtaatcga
     8881 ggtgtttcct ggcggctcgc ctgtggtaat ggtggatccg tgacgcttac tgttgcgcag
     8941 atcgaccgga agaccgacga gctcgtgggg gagtggctcc ccctttcgga cgcggccaag
     9001 aggctggggc tcagcatcgg ccgcgccaag cagctcctga aggacaagaa gctcgccggc
     9061 gtccgcaggg gcggcggcga gccgcagatc cccgcggtgt tcatcgccgg gggcgaggtg
     9121 ctcaagggcc tgcccggcac cctgacactc ctggcggacg cggggtacga cgaggtggag
     9181 tcgatccggt ggctgttcac cccggacgac tcgctgcccg gatccccgat cgacgcgatc
     9241 ctcaagggca ggcacaccga ggtcaagcgc agggcccagg ccctgggttt ctgacccttc
     9301 acgaccccgt ggcattgtgg tcgggtgact gacacccggc ggcagcggct cgcgcaggcc
     9361 aggctctacc tctgcaccga cggcaggagg gaccgcggcg acctggagaa attcctcgac
     9421 gcggtcctgt ccggcggcgt ggacatcgtc cagctcaggg agaagggcct ggaggcccgc
     9481 gaggagctgg agctgctcca ggtcttccgc gcggcgtgtg acaggcacgg cgcgctgctg
     9541 gccgtgaacg accgggcgga cgtcgccttc gccgccgggc ccgacatcct gcacctcggc
     9601 caggacgacc tcccggtccc ggtggccagg gagatcctcg gttccggcgt gctcatcggc
     9661 aggtccacgc actcggcggc cgaggcgtcg gccgccgccg tggagcccgg ggttgactac
     9721 ttctgctgcg ggccgatctg gcccacgccg accaagccgg gccgccccgc gccgggcccc
     9781 gtgctgctcg accacgccgc ccggctgggg gacggccggc cctggttcgg catcggcggc
     9841 atcgacctgg gcaacctcga cgaggtgatg gcgcacggcg tgcggcgggc cgtggtcgtc
     9901 cgggccatca ccgaggccga cgaccccggc gccgccgccg ccgcgctcaa ggccaggctg
     9961 tccaccgtcc cgctctgagc cggccgggcg ccgcctccgg tcaggtgcgc cgggcggtgg
    10021 cggcgacggc gagggcggcc agcgccgcgc gggcctcctc ctcgatcggc gcgtggtcga
    10081 gggcgagcag cgcgtcgtcg agatagcgct tgatcatgcc ctcgcacgcg gcgagcgcgc
    10141 cggtgtcctc gatcaccgcg cgcagccgcc cgacgccgtc ggcgtccagc tcggggtcgc
    10201 cgagaaggga ccgtacgacc cccgcctggg cgggagtggc gtcggcgagc gcgcgtgcga
    10261 tcaggacggt ccgcttgccc tcgcggagat cgtccccggc gggcttgccg gtctccgccg
    10321 ggtcgccgaa cacgccgagg atgtcgtcgc ggagctggaa ggcgatgccc acctgctggc
    10381 cgtactgcac gcagagccgg tcgatccacg agtgcctggc ccgggcggcg aggacgagcc
    10441 cgagcctgag cggctgctcg accgagtact tcccgctctt gtagagggcc acccgcagcg
    10501 cgctgtcgtg ggtgctctcg ccctgcgcct gttcgagcag gtcgaggtac tgcccgcaca
    10561 tcagctcggt gagcatgtgg tcgtgcaccg gctgggcggc ggcgagcgcc tcaggcgcga
    10621 ggccgcaggt gcgccacatc tcaccggacc acaccagcag caggttcccc agcagcacgg
    10681 ccgagccctc gccgaactgc tcggccgagc cgtgccagcc cgcctccgcg tggatccgtt
    10741 cgaaccggcg gtgcgcggac ggcatgcccc tgcgcacgtc gctcgcgtcc atgacgtcgt
    10801 cgtggatgag cgcgctcgcc tgcagcagtt ccagcgaggc ggcggccgcg ttcagccccg
    10861 gatcgtgcgc gtcgccgccc ccggctcgcc acccccagtg gcagaaggcg ggccgcaggc
    10921 gtttgccccc ggccaggaag tcctccgcgg cggtcaggat ggccgccaga tgggggtcgc
    10981 cgaagtgtgg tcgctgccgg tcgatgaact cccggagcgc gcggtccacc tccgtacgga
    11041 tggaatcgag cgaaacggcg gaagcggtca tggtctgaga ctaaccgggg ttgatccgga
    11101 cacacagcac cagatacccc ctcaaggggg tcaactcgtc ccgcttgcga aaacgtccac
    11161 atagcaagac tgcgaccatt ggaaaaagag cggcgctgta acctctgctg tatggctctc
    11221 ggtctgccct cgcggcttcc tgatcgcgtc ccgacggtcc gcgaactgct ggccgcgggc
    11281 gagcgctcgt tctcgttcga gttcttcccg ccgaagaccg acgaggggga gcgccagctc
    11341 tggcgggcca tccgcgagct ggaggcgctg cggccgacgt tcgtctccgt gacctacggc
    11401 gccggcggtt cgacccgcga ccgcacggtc gacatcgtcg agcggctcgc ccacgagacg
    11461 acgctgaccc ccgtcgccca cttcaccgcg gtcgaccact cgatccggga gttgcgccac
    11521 ctcgtcggca ggttcgccga cgcgggcgtg cgcaacatcc tcgccgtacg cggcgacccg
    11581 cgcgggggca accccctgga cgagtgggtc aagcacccgg agggcgtcct gtacgccgag
    11641 gatctggtgc ggctgatccg ccaggcgggc gacttctgcg tgggggtggc ggccttcccg
    11701 tacaagcacc ccaggtcggc gaccatcgag tcggacacga agtatttcgt gcagaagtgc
    11761 cgggccggcg cggactatgc gatcacgcag atgttcttca gggccgagga ctacctgcgg
    11821 ctgcgcgacc gcgtggcggc ccacgggtgc gacaccccga tcatcccggg catcatgccc
    11881 gtcacgcaga tgagcacgat cgcccggtcg gagcagctgt ccggcgcgcc gttcccacgg
    11941 gaggtggccg agcggttcga agccgtcgcc gacgacccgg ccgcggtccg ccgcgtcggc
    12001 atcgagcacg ccgtcgagct gtgccaaaag ctcctcgacg agggcgcgcc cggcatccac
    12061 ttcatcacct tcaaccggtc gagcgcgacc cgcgaggtgt tccaggcgct gcacagcgtg
    12121 cccgcggtcg caggctgagc cgcctccacg ggcgggcgtt cagtcgcggc gggcgtctag
    12181 ctcgggcagc ggcaggcgaa ccccggcgat gacgtactcc tcgtacccgc cggggaagac
    12241 gaacctggtc atcaggtcgg tgaacccgac gtcgcggtag aggtgcctgg ccactgtggg
    12301 ggcgtcgtgc gtcgacagca cggccgtgcg ctcggggcgg ccctcgcaca acgcgtggat
    12361 caggcggcgg ccgaccccct ggccctggta ttcggggcgc acgtggatct cggcgatctc
    12421 cagggcgtcg ccgaaccagt cctccgccgc caccggcccg gcccggtcct gcagcgcccc
    12481 gcgcacgacg tcgtgccacc actgcccccg gccgccgtgg aagccgtacg cgaagccggc
    12541 gacgccgccg ggcgcctgcg cgtcctcggc cagcaggcag tcgaactcgg ggtaggtgga
    12601 gtggttgcgc atgatcgcca gacgcccggc gagctggtcc gacggcgggc gcatggcgac
    12661 cgtgtagatc tccagcacgg tgtccagcac cgccctgaac cggtcgggcc ccacccgtcg
    12721 cagttggatc actcgtcgca cattagcaaa acgtcgcccg gccggtccgg caggtgtcac
    12781 gccacgtcgg tggccgtgcc cccggtgatg cgcagcaact cctcgtagga ggtggggaag
    12841 accgtgtggg ggtgccccgc ggcggcccac accacgtcgt gcttgctcag ccacgtgtcg
    12901 accagcgtcc gtacgggcgc ggggtgcccg acgggggcga cgccgccgat gggctgcccg
    12961 gtgtgctcgc ggacgaactc cggcgtggcc cgccgcacct tcgccgcgcc ggccacgcgg
    13021 gcgatcaggt cggtgtccac gcggtgggcg ccgctggtca gcaccagcag cggcgcgccg
    13081 tccgcgtcga agatcaggct gttggcgatc gcgccgacct cgcagcccag ccgggccgcc
    13141 gccgtcgccg ccgtaggggc ggcctcgtcc agcacgacga cctcgcccgt cgcctccagg
    13201 gcccgcaggg cctcctggac ccggatgacg ttcggatgca acttttctgc cacccgctca
    13261 ctctaaatgg attgccagga catacgtggt cgcttatggc ctcctatgat ctcgtggctc
    13321 acaatcggac catacggtgg gtcctttgat cgggaatccg gcttatgagg ggtgggtcat
    13381 gatgaggggt cgacggcggc tggccgcggc cacgctcgtc gcggtagggg ccgtggcgtt
    13441 cggggcgacc ggcgtcaccg gcacggcgct ggcgcgcacc gccgcgccca cgggcacgct
    13501 gaccacgggc acgctgacca cgggcacgct gaccacgggc acgctgacca cggggaccgt
    13561 gcggtcagcg ctcccggcgc tcccggcgct cccggcgctc ccggcgctcc cggcgagggg
    13621 cgccgtgccc gcgagcgccg ccgcgtaccc gccgttcgcg gcgccgggca agacgctgaa
    13681 gctcggcgcc aagggttcgg ccgtgaaggc gctgcagtcg cggctcaagg agctggggta
    13741 catgccgggc tcggccgacg gccggtacgg cgggaccacg caggcggcgg tctgggcgtt
    13801 ccagaaggtg caggggatcg cgccgaccag cacgatcgcc gccaggacct ggagggcgct
    13861 ggagaacccc cgggcgccca gggtcctggt gcccaggggc aggccgaccc gcgtagaggt
    13921 ggacctgacc aggcaggtga tggttctgta ccggggcggt gcgccggtgc tcatcagcca
    13981 catctccagc ggcagtggca tcccctacac cgagtacgcc atctggaacg gcaagcggca
    14041 gcgcttctcc ggcagcgccc gcacgccgac cggcgactac aggaccacct ggcgggtcaa
    14101 gggctggcac cggtcctacc tggggcagct ctacaatccg attttcttca acggcggcat
    14161 cgcgctccac ggcgcgctgt cggtgccgct ctacccggcg tcgcacggat gcgtgcggct
    14221 gcccatgaac gtggccgagg tcctgcccgg catgctcggc aagggcgttc ccgtgcacgt
    14281 caggggcgcc ttcagacgct agtgacgcca tcccggaggg gtcccgtgcg aggtggtcgc
    14341 gcgggacccc tccggcgtct cctgctcact tttgcgccac actcctcgaa cacgtattcg
    14401 ctgacagcct tgacaggcga catgatcgaa tctatgttcg aaggggtggg cgtgggactc
    14461 gcggctcgcg cccactccgt tggattcgtg ccttcgtcgt cggcggagac ggttgcggca
    14521 cggcccgcgg cgtgggccgg acggggagag gggaagctcc tcgtccggcc gcccacggga
    14581 gtccgggaaa gcgccgggcg atctcgagcg gttcacggga tctcccggcc ggcgaaattg
    14641 tcggtgcgat ctgcgactgt gaggtcaccg gcgaccttcg ccggagtgcc acgactcaag
    14701 gaggcgggca tgactgagca gaatgacgac cagaggggcg gcccccggct ctcgcaggcg
    14761 gtcctggcac acctcgcgga cgccagggcc tgcctcgcgg acgccaccgt cgggcccact
    14821 ccggcggacc gctacgtgtc ggcccatctg gcggctctcc gtgccgccgc cgggatcctc
    14881 gcggcgcgtc cgcggccgat ggacggccgc aggcggcgac tgcgcagcgc ctgggagttg
    14941 ctcccggagg ccgagcccaa gctcgcggac tgggcggcct acttcgcggt gagcgcgacc
    15001 aagcgcgcgg cggcggaggc cgggatggtc cgggccgtca cgcagcacga cgccgaggag
    15061 atcatagcgg aggccgacag gttcgtcggc gaggtcgagt cgatcctcgg cctgcccggc
    15121 cgccccaccc tgcccatggc cggctgacct ccggctcctg ccggggtccg agccgctaag
    15181 ggccggccct ggcgtgatcc tgccggctcg tcctgccggt ccgtcctgcc ggtccgtcct
    15241 gccggcccgt cctgccggcc cgtccggtgg cctctccggt gggcccgccc ggcgggcgcg
    15301 gccgcccccg cgcgattcgc gaggcgccgc cgctcagacg gggtcgcgct ccagagggca
    15361 gctcatgcac cgcggcccgc cgcgtccacg gccgagttcg ctgccgcgga tcgggatgac
    15421 ctcgattccg tgcctgcgca ggtagttgtt ggtggtggtg ttgcgctcgt aggcgacgac
    15481 cacgcccggc tccagcgcca gcacgttgca gccgtcgtcc cactgctcgc gttcggccgc
    15541 gtgcacgtcc tgcgtcggcg tgaggacctt gatgtcgtcc aggccgaggg cccgcgcgat
    15601 cgccttgtgc atgtcctcgg gcggatgatc ggtgaccttc agctcctttt ccgtgtcgcc
    15661 cggctccacc gtgtaggagg ggagcatgcc gagccccgcg tacttggtga agacgccgac
    15721 gtcgacgttg gtcatcacgg tgtcgaggtg catgaacgcg cgggccttgg gcaggtcgag
    15781 cgccacgatg cgggtcgccg accccgcccg gaacaggttg gtcgccagca tctcgaccgc
    15841 ctgcggctgg gtgcgctcgc tcacgccgac gagcacgacg ccgccgccga gcacgaggac
    15901 gtcgccgccc tcgatggtgg ccggggccat gcgcacgccc tcgtaccaga cgttgaaccc
    15961 gccgtcgtcc ggcttggcgt agcccgcggc gaacagcggg tgccagcggt aaacggcctc
    16021 gtagttgacg gtctcccgcc tgcgggcctt cttgcgcatg gcgttgatcg acaccccgtc
    16081 gtacacccag caggaggtgt cgcgggcgaa caggtggttg ggcagcggcg ggaggacgaa
    16141 gtcgtcggtc ccgagcgtgt ggaagacgat ggagcccggg tcgcagccca gctccatgat
    16201 ctcgcgtttg gtgatcccgc cggtcagcag cggcgcgagc gcgtcggcgt cgagggagtc
    16261 gagcgtgttg cggatcgcgt cggcggccag cgggccgaac cagtgctcgt cgacgctgcc
    16321 gtcgaggatg tgcttgcgcg cgtcggggat ctcgatcacc tcgcgcagga ggtcgccgag
    16381 acggtgcacc gtgacgccgt gtccggtcag cacctcgcac cactcgcggt gctcctcgag
    16441 cgcgcggtgc acccagagga cgtcgtcgaa cagcaggccg tccttgttgc ccggggtgag
    16501 ccgcttgagg gcgagttcgg gtatgtcgac cagaacctgg cggagcctgc ccacctcgga
    16561 gcccacgaaa aaggtcatgt cctgcactat ccccgaatgg caggaatcac tcgtacccgc
    16621 ggctccccgg tgcggcggcg ccgtcccggg ccgcgaggcg ggccggagaa acaggcgccg
    16681 tcgcggggag ccgcgtacga gtcgggcggg agatcagaag gactcgacgg cgcggcgggc
    16741 ctccgcgtcg agcacgcccc agtggatgaa ctcctcggtc agctcgaccg gcgacttgtc
    16801 gtagatgacc gcgagcgagc gcaggtcctc ctgccggatg gacagcacct tgccgttgta
    16861 gtcgccgcgc tggctctgga tcgtcgcggc gtagcgcgcc agcgggccgg ccttgtcctt
    16921 cggcagctgg gacaggcgct ccaggtcgat caccagcttg ggcgcgggcg cgagcgggct
    16981 gggggcggcc ccgccgggaa gcagctcaga caccggcact ccgtagaaat ccgcgagctc
    17041 ggcgagcttc tggacggtca ccgcgcggtc gcccctctcg taggagccca cgacgacggc
    17101 cttccaccgt ccgcgggact tctcttccac accatgcagg gacagcccct gctgggtccg
    17161 gatggcgcgc aggcgcgcgc ccagcgactt ggcgtagtca gacggcattg tgtggccccc
    17221 ggctttctat gtctcttctc acttgattgt gcgtccttgt cctaagcgtt ccgaacaccg
    17281 gggctggtac ccgtgaccgg caccttcggt gaccgctgcg tcgggtttta cccaggaagg
    17341 tcgcgtgttg tggttacgga cagtgacggt aaagccgact ctcccaaagg tcaagctgat
    17401 tggaaaaaag agcgtcaaaa cagtgctctc cccgaaatcc ccgacactcg gcacgatgcg
    17461 gcttccgatc cccggcgtgt caccggtgtc cccggcgggc accccgtcgc ctcctcccca
    17521 cgccgccggc gagcggtccc caggcgcatc acccctggcg ggaggggggt tcgcggacgg
    17581 ccctgatact ctaagcagac cgaacaccct ttaagacccg tcccgtgagg cgggaaaggt
    17641 ggtgattttt tcatgtctga tgcccgaaat ccggcccgtg ccgtcctgga ggggcccgac
    17701 atccaccggg cgctgacccg gatcgcgcac gagatcctcg aacggaccag gggcgcggag
    17761 agcgtcgtac tgatcggcat ccccacccgc ggcgccaccc tcgcgcagcg catcgccgag
    17821 cgcatcgcgc agttcgaggg gatcaaggtt cccgtgggcg ccatcgacgt cacgatgtac
    17881 cgcgacgacc tccgcctgcg gcccgctcgg ccgctcggcc gcaccgaact gcccgcggac
    17941 ggcgtcgacg gcaggaccgt cgtcctcgtg gacgacgtcc tctactccgg ccgcaccgtg
    18001 cgcgccgcgc tcgacgcgct gaacgacgtg ggccggccca gggccgtcca gctcgcgacg
    18061 ctcgtggacc gcggccaccg ggaactgccg atccgcgccg actacgtcgg caagaacctg
    18121 ccgacctcca agagcgagaa ggtcaaggtc ttcctggagg agaccgacgg gcgcgacgcg
    18181 gtcgtgctca tcaaggaggg cgaccgatga aacggcacct gatctcgacc ggcgacctca
    18241 cccgcgacga cgccctcctc atcctcgaca cggcggagga gctggcccgg gtctcgcagc
    18301 ggtccatcaa gaagctgccg acgctgcgcg gccgcacggt ggtgaacctc ttcttcgagg
    18361 actccacccg gacccgcatc tcgttcgagg ccgcggccaa gcgcctgtcg gccgacgtca
    18421 tcaacttctc ggccaagggg tcgagcgtgt ccaagggcga gtcgctgaag gacaccgcgc
    18481 tgaccctgga ggccatgggc gccgacgccg tggtgatccg gcacagcgcc tccggcgcgc
    18541 cgcaccgcct ggcctcctgg gtgcgcggca gcgtggtcaa cgccggagac ggcacccacg
    18601 agcaccccac ccaggcgctg ctcgacgcct tcagcatccg ccgccggctg ggccgcctgg
    18661 agggcctgaa gatcgcgatc gtgggcgacg tgctgcacag ccgggtcgcg aggtccaacg
    18721 tgctgctgct gcacacgctc ggcgcggagg tgacgctggt cgcgccgccg accctgctgc
    18781 ccgtcgcggt cggcacgtgg ccctgccagg tctcctacga cctcgacgcc gtgctgccca
    18841 agtcggacgt cgtgatgatg ctgcgggtcc agcttgagcg gatgaacgcg gcctacttcc
    18901 cctcggcgcg ggagtacagc cgccgatacg gcctcgaccg cgaccgcttc gcccgcctgc
    18961 acgacgacgc catcgtcatg caccccggcc cgatgaaccg cggcatggag atctccgcgg
    19021 aggtcgccga ctcgccgcgc tcgacgatcg tcgagcaggt cgccaacggc gtgaccgtcc
    19081 ggatggccgt tctctacctg ttgctcggcg gatccgagcc cgcgatcgga ggcgccgaat
    19141 gaacacgtac gacttccacg aggggacggc tgtgagcacc atcctcatca aaggcgcccg
    19201 gatcctgggc ggcgccccgg ccgacatcct gctgcgcgac ggcgtcgtgg cggagacagg
    19261 cgacctcgcg ggcgcgcggg ccggtcagac ggtcgacgcc gacgggctgg tcgccctgcc
    19321 cggcctggtg gacctgcaca cccacctgcg agagccgggc agggaggacg ccgagaccgt
    19381 cgagacgggc acccaggccg cggcgcgcgg cgggtacacc gccgtccacg cgatggccaa
    19441 cacctccccg gtggccgaca ccgccggcgt ggtggagcag gtctggcggc tcggccaggc
    19501 gtgcggccac tgcgacgtgc agcccgtcgg cgcggtgacc tccggcctcg aaggccgcca
    19561 gctcgccgag ctcggcgcga tggccgactc cgcggcccgc gtgcgggtct tctccgacga
    19621 cggcaagtgc gtgtcggacg ccgtgctgat gcgcagggcg ctggagtacg tcaaggcgtt
    19681 cgacggcgtc gtcgcccagc acgcccagga gccgaggctg accgagggcg cccagctcaa
    19741 cgagggcgag gtgtcggcca ggctcggcct gaccggctgg ccggcggtgg cggaggaggc
    19801 gatcatcgcg cgcgactgcc tgctcgccgc gcacgtcggc tcccggctgc acgtctgcca
    19861 cgtctccacc gccggctccg tcgagatcat ccgctgggcc aagtcgaagg gctgggacgt
    19921 gaccgccgag gtcaccccgc atcacctgct gctgaccgac tcctgcgcgg agacctcgcc
    19981 gctcggcccg tacaaccccc tctacaaggt gaacccgccg ctgcgcaccg ccgacgacgt
    20041 gcgggcgctg cgcgaggcgc tggccgacgg cacgatcgac tgcgtggcca ccgaccacgc
    20101 gccccatccg gtcgaggaca aggagaccga gtggggtgcg gcggccatgg gcatgatcgg
    20161 gctggagacc gccctgtccg tggtgcagga ggccatggtc gagaccggcc tgctcgactg
    20221 ggccggcgtc gccgaccgca tgtcggtcag gccggccagg atcggccgcc tggccgggca
    20281 cggccgcatg atcgagcccg gcgcccccgc caacgtcacc ctgtacgacc cgtcggtccg
    20341 gcagcacgtg gacccctccg cgatggtgtc gaagagccgc aacacccctt acgagggact
    20401 gaccctgccc ggccgcgtcg tcgcgacgtt cctgcgcggc cgccccaccg ttctcgaagg
    20461 gaagctcgta tgacagccct gctcgtactc gaggacggac gcgtcttcga ggggacgccg
    20521 tacggcgccg tgggcgagac gttcggcgag atggtcttca acaccgggat gaccggctac
    20581 caggagacgc tcaccgaccc ctcctaccac cggcagatcg tggcgatgac cgcgccgcac
    20641 atcggcaaca ccggtgtcaa cgaccaggac cccgagtccc gcagggtctg ggtcgccggc
    20701 tacgtggtgc gtgagccgtc gcggatcccg tcgaactggc gctccagcgg gacgctcgac
    20761 gactacctgc gcgcccaggg cgtggtcggc atcgcgatgt ccggcacccg cgccctcacc
    20821 cgccacctgc gcgagcgcgg ggcgatgcgc gcgggcatct tcagcgaggg cggcgacgtc
    20881 gccgacctcg tcgaccgggt gcggcgtgcg cccggcatgg agggcgccga cctggcccgc
    20941 gaggtcagca cgcccgagcc gtacgtcgtg cccgcgatcg gccgcaagcg cttcaccgtc
    21001 gccgcggtcg atctcggcat caaggcgatg acgccgcagc ggatggccga gcggggctgc
    21061 gaggtgcacg t
//
