LOCUS       NZ_JABBWV010000001     21101 bp    DNA     linear   CON 07-NOV-2024
DEFINITION  Microbispora sp. H11081 NODE_1, whole genome shotgun sequence.
ACCESSION   NZ_JABBWV010000001
VERSION     NZ_JABBWV010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora sp. H11081
  ORGANISM  Microbispora sp. H11081
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 1221004)
  AUTHORS   Liu,C.
  TITLE     Selective isolation, identification and anti-microbial activity
            study of Microbispora
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1221004)
  AUTHORS   Liu,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-APR-2020) Microbiological Resources Collection Center,
            Sichuan Industrial Institute of Anotibioctics, 168 Huaguan Road,
            Chengdu, Sichuan 610052, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012999535.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 06:41:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,738
            CDSs (total)                      :: 6,662
            Genes (coding)                    :: 6,604
            CDSs (with protein)               :: 6,604
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 4, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1 (5S, 16S)
            partial rRNAs                     :: 1, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 58
            CDSs (without protein)            :: 58
            Pseudo Genes (ambiguous residues) :: 0 of 58
            Pseudo Genes (frameshifted)       :: 7 of 58
            Pseudo Genes (incomplete)         :: 54 of 58
            Pseudo Genes (internal stop)      :: 2 of 58
            Pseudo Genes (multiple problems)  :: 5 of 58
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:04:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 366805
            Orig. end                         :: 387906
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBWV010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21101
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21101
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21101
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11101](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11101
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(116..131)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    696..710
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            1252..2019
                     /gene="recO"
                     /locus_tag="HHX31_RS01580"
     CDS             1252..2019
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131431.1"
                     /locus_tag="HHX31_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecO"
                     /protein_id="WP_169944344.1"
                     /transl_table=11
                     /translation="MSLYRDEGVVLRTQKLGEADRIITILTRRTGKVRGVAKGVRRTMS
                     RFGARLEPFSHVDLQLHSGRSLDVITQVETLHPYGEAIVADYARYTAGTAMLETADRLT
                     VGEKEPALRQFLLLVGGLRTLAQDGHEARLVLDAFFLRSLAVAGYAPALSECARCGAEA
                     VRAFAIVAGGVVCGACRPAGAAVPAAETIALMIALLRGDWATADASEPRHRAECSGLVA
                     AYLQWHLEHGIRSLRHVEREWPGQPARGEARIV"
     gene            2143..2952
                     /locus_tag="HHX31_RS01585"
     CDS             2143..2952
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536659.1"
                     /locus_tag="HHX31_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isoprenyl transferase"
                     /protein_id="WP_169944346.1"
                     /transl_table=11
                     /translation="MVRPVTPHPSGAVPPAIPRDLLPRHVAIVMDGNGRWAKTRGLPRT
                     EGHKMGEASLFDVIEGAIELGIPYLSAYAFSTENWKRSPDEVRFLMGFNRDVIRRRRDQ
                     LHAMGVRVRWAGRPGRLWKSVIKELEDAERMTAGNSTLTLQFCVNYGGRAEIVDAAVRL
                     ARDVAAGRVKPDKVTEKIFARYLDEPEIPDVDLFLRSSGEQRTSNFLLWQSAYAEMVFL
                     NRLWPDFDRRDLWHACEIYAKRDRRYGGALPNAVSGAGAADGYGEAS"
     gene            complement(2954..3502)
                     /locus_tag="HHX31_RS01590"
     CDS             complement(2954..3502)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131433.1"
                     /locus_tag="HHX31_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_311931128.1"
                     /transl_table=11
                     /translation="MPFSHDMVYSLATVVELINTATGERDGLAELGDLEEFVRRREVSG
                     VRELTGRDLAEVRSLREEFTAVFTAEDQPTAVGLLNTLLRRTRITPSLTEHDGHPLHVH
                     YFAPDASLAEHLAADCGVALAHVLVENERERLRTCAAPDCGHVFVDESRNRSRVYCDSR
                     TCGNRMHVAAYRARRRDAS"
     gene            complement(3564..3965)
                     /locus_tag="HHX31_RS01595"
     CDS             complement(3564..3965)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017594646.1"
                     /locus_tag="HHX31_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_169944348.1"
                     /transl_table=11
                     /translation="MTKSRDAVHEILRQSRGFRSAQDVFAEMRSVGSKIGLTTVYRALQ
                     SLSDAGRVDVLRTDEGESVYRACQTDSHHHHLVCRVCGRTVEVAGPDVERWAEVVGAEH
                     GFIDVTHTVEVFGTCSSCAESCGEPPGKG"
     misc_feature    3956..3976
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     gene            complement(4021..4443)
                     /locus_tag="HHX31_RS01600"
     CDS             complement(4021..4443)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131435.1"
                     /locus_tag="HHX31_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6703 family protein"
                     /protein_id="WP_311931131.1"
                     /transl_table=11
                     /translation="MGSETEPPRREVPAHPLARKTPARTNQASSRARRPLPPGEQFYTP
                     GATGLRAEIERRSATPLVFLFQQPRWLAPLVLVVLLIAGLVMPDWRGGVAVLPVLAFIV
                     WLAYLSWPSLRPVGRLLRVVVGTFLVLLAATRFGLI"
     gene            4568..4885
                     /locus_tag="HHX31_RS01605"
     CDS             4568..4885
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131436.1"
                     /locus_tag="HHX31_RS01605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_169944350.1"
                     /transl_table=11
                     /translation="MLAVIRYSVPGARADEFAAQAQAILDLLAAQPGYLRGQIGRSVDE
                     PALWAVVSEWEGAGYYRRALSAARMVMYPLMTLMINEPSAFEGVYALPDEGANAGAPGK
                     A"
     gene            5055..6440
                     /locus_tag="HHX31_RS01610"
     CDS             5055..6440
                     /EC_number="6.1.1.14"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889071.1"
                     /locus_tag="HHX31_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine--tRNA ligase"
                     /protein_id="WP_169944352.1"
                     /transl_table=11
                     /translation="MARRTDVLETIVSLAKRRGLVFPSSEIYGGLRASWDYGPLGVELK
                     NNVKREWWKAMVQGRDDVVGLDSCVILAREVWQASGHVDTFTDPLTECQSCHKRYRADH
                     LIEAYEAKHGSEPAGGLADLTCPNCGNKGAFTQPRQFSGLLKTFLGPVEDESGLAYLRP
                     ETAQGIFINYLNVQQSARRKIPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKP
                     GTDEEWHQYWIDERLRWYVDLGINKDNLRLYEHPKEKLSHYSKRTVDIEYRFNFAGGEW
                     GELEGIANRTDFDLTAHGKASGTDLSFFEQESGERYVPYVIEPAAGVDRATLTFLVDAY
                     TVDQAPNAKGVMEERTVMRLDHRLAPVKVAVLPLSRNADLSPKARDLAARLRRRWNVDF
                     DDAGAIGRRYRRQDEIGTPFAITVDFDTLEDQAVTIRERDSMAQQRVALDQVESYLRQH
                     LND"
     misc_feature    5075..5090
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.31"
                     /tool="antismash"
     misc_feature    5075..5093
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.78"
                     /tool="antismash"
     misc_feature    complement(5077..5091)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.39"
                     /tool="antismash"
     gene            complement(6496..9573)
                     /locus_tag="HHX31_RS01615"
     CDS             complement(6496..9573)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.5"
                     /locus_tag="HHX31_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_169944354.1"
                     /transl_table=11
                     /translation="MRFEVLGPIQVIRDGRPVFVGSARKLRTLLAGLVARADQTVSGDF
                     LTTVLWGDRPPVSARSNLQSYVHQLRVQLGAERLLSKPDGYLLLAHGEVDAARFRGLAA
                     EGSAALDRRDHESAGRCFRRALDLWRGPAFGEFLDSGPLAEEALSLEQLRLTVYERWAE
                     TELALGRHAEAVAELRAVAQSHPYQEGLHAHLMLALYRSGRQTEALETYAAVRGLLADE
                     LGLEPSPVLRRAHEAILRGDERTDPPGRAGEWPAGGAVIPRQLPPTIADFTGRDDEVAT
                     LRDALSPGGGQAPAICAISGMGGVGKTTLALRVAHLVAGEFPDGQLYVGFSAADHAADH
                     AADHHATDDRAAVNRALESMLRALGVGGSAVPESIGDRTALYRSLLAGRRMLVVIDNVA
                     GEAQVGPLLPGSGACGVLITGRPRLTGLAGVRHLRLDVFRPAQAVELLARITGPEQVRA
                     APGEATEIVRLCDHLPLAVRAAGARLASRPDWPLARVADLLRDERRRLDELSVGDLTVR
                     ASLGLSYTALSPSARRLYYLLSELHTPDFAGWVAAAVLGASPEEAERPLGELLGADLLA
                     VAGADAAGQSRYRFHDLIRLHARDRAAAEAAPGVVHAAVTRALGGWLVLARRADTRLPG
                     RVFPTLAAEGAPYEPQVEISDASAWFEAERGALRAAVEQAAALGAHTLCWQLADAAVNF
                     FELHDYYDDWESTSRIALRACERAGDDRGRAFMLRDLTECLRMGPWHAEDEALEHALTA
                     AGLFESAGDVLGEVDARILAGTAFLVRGEPGKAVAYLDAALAKARHAGYVLGQVEAEWQ
                     LGYGHRVLGDPTRAAAHLEASLRLAEDVPLPSQLCRIHSLLGIVRREEGRLAEAEAHFT
                     RGVTLARSLRSMSGEITILPHLGMTYVKLGDPRGRDVLARSIRLARQWGARFQEAMSLG
                     ALGELEQAEGDHALAVAHTVAAVEIWRELASPFHEAQALKFLGALHAATDPDRARTAWS
                     AARRLFAQLDNHPEVEELTTLLGTAERHRNPDDDKR"
     misc_feature    9715..9735
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.93"
                     /tool="antismash"
     misc_feature    9774..9783
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     aSDomain        10001..10291
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HHX31_RS01620_Pantocin_Microcin_RRE.1
                     "
                     /evalue="6.10E-22"
                     /identifier="RREFam017.1"
                     /label="HHX31_RS01620"
                     /locus_tag="HHX31_RS01620"
                     /protein_end="97"
                     /protein_start="0"
                     /score="68.6"
                     /tool="antismash"
                     /translation="MRKPRVKRVHLPTVLPDGRIRIGLGQYGVAAELQDDAEGNIARIL
                     TLMDGTRDVERICADFVADSPEFDGENVREIVEALVAEGFVEDAGAAPPANL"
     gene            10001..11101
                     /locus_tag="HHX31_RS01620"
     CDS             10001..11101
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="HHX31_RS01620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_169944356.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.3e-20,
                     bitscore: 68.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 7.9e-35, bitscore: 116.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKPRVKRVHLPTVLPDGRIRIGLGQYGVAAELQDDAEGNIARIL
                     TLMDGTRDVERICADFVADSPEFDGENVREIVEALVAEGFVEDAGAAPPANLSARELER
                     YEPARHFFSWVDTVPRESPYTVQSRIKQARVTVLGVGGTGSAVAAGLVASGIGALHVAD
                     FDEVQESNLTRQLLYTEQDVGGSKVERAVARLRAMNGLVTVTGSDVKATGADDVAALMA
                     GCDVFVLCADEPQPDIMLWTNEAALRTGTPWFVSFYAGPMAVVGSFHPGETGCWLCMRR
                     DEDAREGALGERPLVAGHGRPNAVVAASANISGHLCALEVTYHLGGLRTQARGRIFHWN
                     FAVWDHVYALDVPRHDDCPACGSVRG"
     gene            11112..12374
                     /locus_tag="HHX31_RS01625"
     CDS             11112..12374
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHX31_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_169944358.1"
                     /transl_table=11
                     /translation="MTEPVAVGPAGTLLLRPLSVQADDDPDSVIVGRPELGEFVSLPAL
                     YGRAIELLGDGLTVGEVQRRIEDEHDVELDVVGLVEALVGLGFVARLDGADLPDPADAA
                     PPPHLPWLADRHVRWLFGRPMAVLCAVVVVAALVTLVDRPDLVPVYHDFFWSDYIGLTT
                     LVNTAMFSVVISLHELMHLAAARSLGTPARIGLGTRLHNLVVQTDVTAIWSVPRRSRYR
                     VYLAGTFCDLFLLAALLLVLAHANPPEGVAALLRALALVTMLSMPMELHVYMRTDFYFV
                     LADLLRCRNLFGDGLDYARYLLRRVVAVARRARPPADPSAELSAHERRAVRIYAVLLVP
                     AATVALGMFAIYTLPIVAGSLILALAAVWGGLNGGPVLQGVDGGLFLLVEGGIHTLFVV
                     TFVRSHPHWFRRRRPGAPAVR"
     gene            complement(12402..13898)
                     /locus_tag="HHX31_RS01630"
     CDS             complement(12402..13898)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (98-455). E-value:
                     1.6e-24. Score: 78.8. Matches aSDomain:
                     nrpspksdomains_HHX31_RS01630_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131438.1"
                     /locus_tag="HHX31_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_311931133.1"
                     /sec_met_domain="PF00561 (E-value: 6.8e-38, bitscore:
                     126.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRGVSARRIWPVVAATVAGLGALAATAGCGGARVVPEEYVTATP
                     SLQWKACEETASSSGFECATLQVPLDYAKPEGRQIGIALIRLRATDQSRRIGSLVFNFG
                     GPGGSGVTTLMNAAHAFSTLNTRYDLVSFDPRGVERSSGIRCLSGPQMDQYMTREPSEN
                     TATETKLVTEFARGCERNAGWILPYVGTVNVARDLELLRGALGEPNLNYLGFSYGTHLG
                     AVYATQFPKKVGRMVLDSAVDPSIDMLEMAKTQALGFQKAYEDYLADCAKTPTSCPLGA
                     DPAAANATVLKLLDTLARTPGKVGSRPVTEDVARAGITQALYSKFTWPLLTEALDEGRK
                     GKLDGLLALADQYAGRQPDGTYSTLQFSLPSVLCVDSTDRPSVAQGEELARRLEKQTPI
                     FGPTAISAGSCSVWPVRGDDAARHIDATGSNPILVVGVTNDPATPYQWAPRLTEQLRTG
                     VLLTLNGEGHGAYGQSKCINDKVDAYLLEGTVPAKGTRCD"
     aSDomain        complement(12534..13604)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHX31_RS01630_Abhydrolase_1.1"
                     /evalue="1.60E-24"
                     /label="HHX31_RS01630_Abhydrolase_1.1"
                     /locus_tag="HHX31_RS01630"
                     /protein_end="455"
                     /protein_start="98"
                     /score="78.8"
                     /tool="antismash"
                     /translation="LVFNFGGPGGSGVTTLMNAAHAFSTLNTRYDLVSFDPRGVERSSG
                     IRCLSGPQMDQYMTREPSENTATETKLVTEFARGCERNAGWILPYVGTVNVARDLELLR
                     GALGEPNLNYLGFSYGTHLGAVYATQFPKKVGRMVLDSAVDPSIDMLEMAKTQALGFQK
                     AYEDYLADCAKTPTSCPLGADPAAANATVLKLLDTLARTPGKVGSRPVTEDVARAGITQ
                     ALYSKFTWPLLTEALDEGRKGKLDGLLALADQYAGRQPDGTYSTLQFSLPSVLCVDSTD
                     RPSVAQGEELARRLEKQTPIFGPTAISAGSCSVWPVRGDDAARHIDATGSNPILVVGVT
                     NDPATPYQWAPRLTEQL"
     misc_feature    complement(13999..14013)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.22"
                     /tool="antismash"
     misc_feature    13999..14014
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.71"
                     /tool="antismash"
     misc_feature    complement(14059..14074)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.05"
                     /tool="antismash"
     misc_feature    complement(14106..14121)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.37"
                     /tool="antismash"
     gene            14249..16900
                     /gene="ppdK"
                     /locus_tag="HHX31_RS01635"
     CDS             14249..16900
                     /EC_number="2.7.9.1"
                     /GO_function="GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006090 - pyruvate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ppdK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131439.1"
                     /locus_tag="HHX31_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="WP_169944359.1"
                     /sec_met_domain="PPDK_N (E-value: 8.1e-30, bitscore: 100.1,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKYVCDFTEGNKDLKDLLGGKGANLAEMTNIGLPVPPGFTITTE
                     ACRHYLRHGGMPDGLDAEIGEHLAVLEARMGKRLGQSDDPLLVSVRSGAKFSMPGMMET
                     VLNIGLNDDSVLGLAKQSGNDRFAWDSYRRLIQMFGKTVLDIDGELFEDAMDDLKAGRE
                     DTDLDASDLQRLVETFKDIVRDRTGRDFPADPREQMDLAVRAVFDSWNAPRAVLYRRQE
                     RIPADLGTAVNVVAMVFGNLGADSGTGVAFTRDPGSGRQGVYGDYLRNAQGEDVVAGIR
                     NTVPLQELETINPAAYRELLDIMATLERHYRDLCDIEFTIERGKLWMLQTRVGKRTAEA
                     AFCIATQLVDEGLIDMDEAVTRVTGDQLAQLMFPRFAATEGGRRLATGMNASPGAAVGK
                     AVFSSERAVELAGQGEAVILVRRETNPDDLAGMIAAKGVLTSRGGKTSHAAVVARGMGK
                     TCVCGAEELEVDTRARRFTAPCGTVVNEGDVISIDGGTGAVYLGEVPVTASPVAKYFEG
                     EPSEDELAEDELVRAVDRIMTHADSVRRLAVRANADTPEDAARARRYGAQGIGLCRTEH
                     MFLGERRRLVEDLILATTPKERQVALEALEPLQTGDFTGILTAMRGLPVTIRLIDPPLH
                     EFLPDLTDLAVRVALAGDEAVDRDRRLLEAVKRLHEQNPMLGLRGVRLGLTIPGLFAMQ
                     VRAIAAAAKLVKGARAEIMIPLVGAVQELEIVREEAERILAEAGVDAAIGTMIEVPRAA
                     LTAGQIAEAAEFFSFGTNDLTQMAWGFSRDDVESAFFGKYLDLGVFGVSPFESIDREGV
                     GRLMRIAVEEGRRTRPGLKIGICGEHGGDPASIHFCQEIGLDYVSCSPFRIPVARLEAG
                     RAALTCAESDTR"
     gene            17051..18949
                     /locus_tag="HHX31_RS01640"
     CDS             17051..18949
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020545407.1"
                     /locus_tag="HHX31_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_311931136.1"
                     /transl_table=11
                     /translation="MRIRRRPPALAIAAALLCILPALLAAAPMPSAVPPLTPREAAGQA
                     PAGRADEPSSSRQYQVDGPATVAQRNAVARTGAAIDEVHGRSLVVTATLQEADAIRRLG
                     FRITELPPPAETGGPQTFDFPTGDSGYHNHAELSALVDQVVAAHPAIARRFSYGRSYEG
                     RDLMGVKISDNVATDENEPEVLFTAHQHAREHLTVEMAIYLLRLFTDNYGGDAQITDLV
                     NTREIWILPDLNPDGGEYDVATGSYRSWRKNRQPNSGTSSVGTDLNRNWGYRWGCCGGS
                     SSTPSSETYRGAAAESAPEVRAVADFVRGRVVGGVQQIKAAIDWHTYSELVLWPYGYTT
                     ADTGPGMTQDDRDAHAALGRSMAATNGYTAEQSSDLYVTDGSIDDWLWGTYKIFTYTFE
                     MYPKGSSPGFYPPDEVIDRETSRNRVAALLLVQNADCVYRVIGKESAYCGTGTPPTVVY
                     SDTFETATGWTVNAAGTDTATSGAWERADPAATSSSGAKQLGTTVSGTYDLVTGAAAGT
                     SAGDRDVDGGVTTVTSPPITLPASGTLTLSLSWYLAHGSNSSAADYFRVKVIGGTTGTV
                     FEQLGAATDRDAAWSVATASLTGFAGQTVRIQFEAADLATASLVEAAVDDVRITRS"
     gene            complement(18976..19767)
                     /locus_tag="HHX31_RS01645"
     CDS             complement(18976..19767)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852792.1"
                     /locus_tag="HHX31_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_311931138.1"
                     /transl_table=11
                     /translation="MVDDELAEVLRSGPFERALRAAIRTRGLSLDRLHSRLRERGFEVS
                     MSSLSYWQRGRSRPERAASLAAVRELEVILSLPEYALIGLLGPPRPRGRRPETLTVLSH
                     HEQAVVSAGLRHRVSARVVLRAAAPGVDRYEVTHPPGTRLLRTRGCRPGRGGDDGSGLL
                     TELIFPHPLATGETHVVEYVTDVAAADRYDRRLRDPVEQHLVQVRFTDGRLPVRCFHTW
                     SPDPAARPRDAGELRVDAFGTAHVVDTGARPGVRGIRWEWA"
ORIGIN
        1 gcccgccgcc agcaggccga gggcgatcga gatcagcgtc acctggttgg gggtgagccc
       61 acggcgggcc gcccagcggg cgatgaagcg cgagtaggtg ctgacgaaga acgtggtgaa
      121 gaagccgtcg gcgcccttca ccgcgttgtc gagccgggcc ctgtcctcgt cgaaaccggc
      181 catctcggcg agcgcctcgt cggcctccgc ctggctgcgg acacggcgga agaacaggtc
      241 gcgccggccg cgccggccca ccgacacccc gcgccggacg aggccgagca cgagaagctc
      301 ggtcacgtcg tcctcggggc cgaacaggtg ggccatgtcc gccagttccc tggcgacctc
      361 ggcgaggacc ggaaggtgcc gctggtggag gtggagcggc ccgagcagcg ccgcgttcgg
      421 ccgggtcacc gcgtggtagg cggtgccgac cgagatgatc cggctgcggc cgatgcgggt
      481 gcgctggggc aggccctcga tgaccttgtc gccgatctcg ggcgccgcct cctcgatggg
      541 cacgagttcg ggcgcggact cgtcctccag ttcgtcgcgc tgctcgcgga cgaccagcgc
      601 gatggcaccg cgcttggcct tggtgatctg gtagagcagc tcgtcgtgca ccagcgagtc
      661 ggccggcagg atcagcaggt tctcctcggc gccctcgacc acgtcggcca gcgcgcgcag
      721 gtctcccgcg acgtccgggc tctccaccac ccgtccgtac ggcctgcggt aggcggcggc
      781 gtcccccggc cgggcgatcg tcgtcggctg ggggtccatg acggcggcct gcgcgagcag
      841 cctgtcgtac gcggagggag ccccaggcag cgatttgaga gtgatgtccg cgggcagggc
      901 gggctggccg ccgggcggcg ggggactgat cgggccgggc ggggcgccca gcaggaccac
      961 gcgggtcatg gcaacctttc acgcaacggg gggagatcag gcccgcaggc ttgaccggcg
     1021 tggggaagcc cgccggaagc caaagcttag tgagctttca gttgagccga tgcatcccag
     1081 gtttaccgta cggccctgtg atgtacagct cggggatggt ttgtcaccgg gcattgtcgc
     1141 cggatcatta ccgaattttc accgtttgtg tgcatatgcg gggtcaaggt ccgcgccgac
     1201 gaatgtcccc gcggcgcggt gggcgcccgg ccgcgcccat acgatggcgg ggtgagtctc
     1261 taccgggacg agggcgtcgt gctgcgcacc cagaagctgg gcgaggcgga ccgcatcatc
     1321 accatcctca cccggcgcac gggcaaggtc cgcggcgtgg ccaagggagt gcgcaggacc
     1381 atgtcgcgct tcggcgcgcg gctggagccg ttctcccacg tcgacctgca actccacagc
     1441 ggcaggtcgc tcgacgtgat cacccaggtc gagaccctcc acccgtacgg cgaggcgatc
     1501 gtggccgact acgccaggta caccgccggc accgcgatgc tggagacagc cgaccggctg
     1561 acggtggggg agaaggagcc cgcgctgcgc cagttcctgc tgctggtcgg cggcctgcgc
     1621 acgctcgccc aggacggcca cgaggcccgg ctggtgctcg acgcgttctt cctgcgctcg
     1681 ctggccgtgg cggggtacgc acccgcgctg tcggagtgcg cgcggtgcgg cgctgaggcc
     1741 gtgcgcgcct tcgcgatcgt cgcgggcggc gtggtgtgcg gcgcctgccg cccggccggc
     1801 gccgcggtgc ccgccgcgga gacgatcgcg ctgatgatcg ccctgctgcg cggcgactgg
     1861 gcgaccgccg acgcctccga gcccaggcac cgcgcggagt gcagcggcct ggtggccgcc
     1921 tacctgcagt ggcaccttga gcacggcatc cgctcgctgc gccacgtcga gcgcgaatgg
     1981 ccgggtcagc cggcccgcgg cgaggcgagg atcgtctgac ccgccctcgg tggcgcctgc
     2041 cacccggccg ggcggggtcc gcacaggacc cgcacagcac tcgcacatga cccgcacctc
     2101 caccgcgtct gaggacaggt caggacgcaa taccctcgac acatggtccg tcctgtcact
     2161 ccacacccgt ccggggccgt gccgcccgcc atcccgcgcg acctgctgcc gcgacatgtg
     2221 gcgatcgtca tggacggcaa cggccgctgg gccaagacac gcgggctgcc caggaccgag
     2281 ggacacaaga tgggtgaggc gtcgctgttc gacgtcatcg agggcgccat cgagctcggc
     2341 atcccctacc tgtcggcgta cgccttctcc acggagaact ggaagcgctc gcccgacgag
     2401 gtgcgcttcc tcatggggtt caaccgcgac gtgatccgca ggcggcgcga ccagctccac
     2461 gcgatgggcg tgcgggtccg ctgggccggg cgtcccgggc ggctgtggaa gagcgtcatc
     2521 aaggagctcg aggacgccga gcggatgacg gcgggcaaca gcacgctgac cctgcagttc
     2581 tgcgtgaact acggcggacg cgcggagatc gtggacgcgg cggtgcggct cgcccgcgac
     2641 gtcgccgccg gccgggtcaa gccggacaag gtgacggaga agatcttcgc ccgctatctg
     2701 gacgagccgg agatcccgga cgtcgacctg ttcctgcgct cctccggcga gcagcgcacc
     2761 tccaacttcc tgctctggca gtccgcgtac gccgagatgg tcttcctcaa ccggctgtgg
     2821 cccgacttcg accgccggga cctgtggcac gcgtgcgaga tctacgccaa gcgcgaccgc
     2881 aggtacggcg gcgccctgcc caacgccgtc tccggcgccg gtgccgccga cgggtacggc
     2941 gaggcgtcct gactcaggag gcgtcgcggc ggcgggcccg gtacgccgcg acgtgcatgc
     3001 ggttcccgca ggtgcggctg tcgcagtaga cccgggagcg gttccgcgac tcgtccacga
     3061 agacatgccc gcagtcgggg gcggcgcagg tgcgcaggcg ctcccgctcg ttctcgacga
     3121 gcacgtgggc gagcgcgacg ccgcagtcgg cggccagatg ctcggcgagc gacgcgtccg
     3181 gcgcgaagta gtggacgtgg agagggtggc cgtcgtgctc ggtcaggctc ggcgtgatgc
     3241 gggtgcgccg cagcagcgtg ttgagcagtc cgaccgccgt cggctggtcc tcggcggtga
     3301 acacggcggt gaactcctcg cgcagggacc ggacctcggc gaggtcgcgc ccggtcagct
     3361 ccctgactcc gctgacctcc cgcctgcgga cgaactcctc caggtcgccg agttcggcca
     3421 gcccgtcgcg ctcgccggtg gcggtgttga tcagctccac caccgtcgcc agcgaataca
     3481 ccatgtcatg gctgaacggc acgccatctc cctcatgtcg cggcgcagga agcgtacctc
     3541 tcgaaaggcc cgtgcggggc gggtcagccc tttcccggcg gctctccgca ggactccgcg
     3601 cacgaggagc aggtgccgaa gacctccacg gtgtgcgtga cgtcgatgaa gccgtgctcg
     3661 gccccgacga cctcggccca gcgctccacg tcgggcccgg ccacctcgac cgtacggccg
     3721 cagacccggc acaccaggtg gtggtggtgg gagtcggtct gacaggcgcg gtagaccgac
     3781 tcgccctcgt cggtgcgcag cacatcgacc cggccggcgt cggagagcga ctggagcgcc
     3841 cggtacacgg tcgtcaggcc gatcttcgag ccgaccgagc gcatctcggc gaacacgtcc
     3901 tgtgcgctgc ggaacccccg gctctgccgg aggatctcgt gcacggcgtc gcggctcttc
     3961 gtcatcaaga ctcctgtgta cggcttcgcc ctacgaccta caaggttagg ccggttcgcg
     4021 ctaaatcagt ccgaaacggg tggcggcgag gaggaccagg aacgtcccga ccaccacccg
     4081 caggagccgg cccaccgggc gcagggacgg ccatgacagg taggccagcc agacgatgaa
     4141 cgcgagcacc ggcagcacgg ccacgccgcc ccgccagtcc ggcatcacca gtccggcgat
     4201 caggaggacc accagcacca gcggggcgag ccagcggggc tgctggaaca ggaagaccag
     4261 cggggtggcg ctccggcgct cgatctccgc gcgcagcccg gtcgcgccgg gcgtgtagaa
     4321 ctgctcgccg ggcggcagcg gacgccgagc ccgggaggac gcctggttcg tccgggcggg
     4381 ggtcttcctc gccagcggat gcgccggcac ctcacggcgc ggcggttctg tttcgcttcc
     4441 cacgcgttcg agcctagtcc cgcgaccgcc gaagttcgcc cgtcccgtcg gggtcgtccg
     4501 cccgcgagcg gacgggcgcg tcgcccctcc cggtgaggcg cgggggcggg gtggcatgct
     4561 gggcggcatg ctcgccgtga tccgttactc ggtgccgggc gcccgcgccg acgagttcgc
     4621 cgcacaggcg caggccatcc tcgatctgct ggccgcgcag ccgggatacc tgcgcgggca
     4681 gatcggcagg tcggtggacg agccggccct gtgggccgtg gtcagcgagt gggagggcgc
     4741 gggctactac cgccgcgccc tgtcggcggc gcgaatggtc atgtatccgc tgatgactct
     4801 tatgatcaac gagcccagcg ccttcgaagg cgtctacgcg cttcctgacg agggggcgaa
     4861 cgcgggcgca ccgggcaagg cttgagcgcg aggccgccgg attcccctaa gcttgagcac
     4921 agatccgggc aggtggccgg acattccgcc gccgccggca ggcggccggc aggcccgccc
     4981 gctcagcgag caccgatcag cgcatcgctg aacccgatcc caacgccgac acccagccgg
     5041 atggagttcc actgatggca cgtcgcaccg acgtattgga aacgattgtc agcctggcca
     5101 agcgccgcgg gctcgtcttc ccgtcgagcg agatctacgg aggcctgcga gcgtcctggg
     5161 actacggccc cctcggtgtc gagctcaaga acaacgtgaa gcgcgagtgg tggaaggcca
     5221 tggtgcaggg ccgcgacgac gtcgtcggcc tcgactcctg cgtcatcctc gcccgcgagg
     5281 tctggcaggc cagcggccac gtcgacacct tcaccgaccc gctcaccgag tgccagtcct
     5341 gtcacaagcg ctaccgcgcc gaccacctca tcgaggcgta cgaggccaag cacggcagcg
     5401 agccggccgg cggcctggcc gacctcacct gccccaactg cggcaacaag ggcgccttca
     5461 cccagccgag gcagttcagc ggcctgctga agacgttcct cggcccggtg gaggacgagt
     5521 ccggcctggc gtacctgcgg ccggagaccg cccagggcat cttcatcaac tacctgaacg
     5581 tccagcagtc ggcccgcagg aagatcccgt tcggcatcgg ccagatcggc aagtcgttcc
     5641 gcaacgagat caccccgggc aacttcatct tccgcacccg cgagttcgag cagatggaga
     5701 tggagttctt cgtcaagccg ggcacggacg aggagtggca ccagtactgg atcgacgagc
     5761 gcctgcgctg gtacgtcgac ctcggtatca acaaggacaa cctccggctc tacgagcacc
     5821 cgaaggagaa gctgtcccac tactcgaagc ggaccgtgga catcgaatac cgcttcaact
     5881 tcgccggcgg cgagtggggt gagctggagg gcatcgccaa ccgcaccgac ttcgacctca
     5941 ccgcgcacgg caaggcgtcc ggcaccgacc tgtcgttctt cgagcaggag tcgggcgagc
     6001 gctacgtgcc gtacgtcatc gagccggcgg cgggtgtgga ccgcgcgacg ctgacgttcc
     6061 tcgtcgacgc ctacaccgtg gaccaggcgc ccaacgccaa gggcgtgatg gaggagcgga
     6121 ccgtgatgcg cctcgaccac cgcctcgccc cggtcaaggt cgcggtgctg ccgctgtcgc
     6181 gcaacgccga cctgtcgccg aaggcccgcg acctcgccgc gcggctgcgc cgccggtgga
     6241 acgtcgactt cgacgacgcg ggggccatcg gccgccgcta ccgccgccag gacgagatcg
     6301 gcacgccgtt cgcgatcacg gtggacttcg acacccttga ggaccaggcc gtgacgatcc
     6361 gcgagcggga ctccatggcc cagcagcggg tcgcgctcga ccaggtcgag tcgtacctgc
     6421 gccagcacct caacgactag acgagcaggt cacaagtcgc ccagggcggc cgtccaggat
     6481 cggacggccg cccaatcacc ttttgtcgtc atcggggttc cggtgccgct cggcggttcc
     6541 gagcagcgtc gtcagctcct ccacctcggg gtggttgtcg agctgcgcga acagccggcg
     6601 ggccgcgctc caggccgtac gggcgcggtc cgggtcggtg gccgcgtgca gggcgccgag
     6661 gaacttgagc gcctgcgcct cgtggaaggg gctggcgagc tcgcgccaga tctcgacggc
     6721 ggcgacggtg tgggcgacgg cgagggcatg gtcgccctcg gcctgttcga gctcgccgag
     6781 cgcgcccagc gacatggcct cctggaaccg cgcgccccac tggcgggcca gccggatgct
     6841 cctggcgagc acgtccctgc cccgcgggtc gcccagcttg acgtaggtca tgccgaggtg
     6901 cggcaggatc gtgatctcgc cgctcatgct gcggagcgaa cgggcgagtg tcacgccacg
     6961 tgtgaagtgc gcctccgcct cggcgagacg gccctcctcc cgccgtacga tgccgagcag
     7021 gctgtggatc cggcacagct gcgacgggag gggcacgtcc tcggccagcc gcagactcgc
     7081 ctccaggtgg gcggcggccc tcgtgggatc tccgaggacc cggtggccgt acccgagctg
     7141 ccactcggcc tcgacctgac cgagcacgta acccgcgtgc cgcgccttcg ccagcgccgc
     7201 gtcgaggtag gccacggcct tgccaggctc tccccggacc aggaacgcgg tgccggcgag
     7261 gatccgggcg tcgacctcgc cgaggacgtc gcccgcgctc tcgaagagcc cggcggcggt
     7321 gagcgcgtgc tccagcgcct cgtcctcggc gtgccagggc cccatgcgca ggcactcggt
     7381 gaggtcgcgc agcatgaagg cgcggccgcg gtcgtccccg gcgcgctcgc aggcgcgcag
     7441 cgcgatccgg ctggtcgact cccagtcgtc gtagtagtcg tgcagctcga agaagttgac
     7501 ggccgcgtcg gcgagttgcc agcagagcgt gtgcgcgccg agcgcggcgg cctgctcgac
     7561 cgcggcccgg agcgcgcctc tttccgcctc gaaccaggcg gaggcgtcgg agatctcgac
     7621 ctgcggctcg tacggcgcgc cttcggccgc gagggtgggg aacacccggc cgggcagccg
     7681 ggtgtcggct cgcctggcga ggaccagcca cccgccgagc gcacgggtca cggccgcgtg
     7741 gaccacgccc ggggcggctt ccgcggcggc gcggtcgcgg gcgtgcagcc ggatcaggtc
     7801 gtggaagcgg tagcgggact ggccggcggc gtcggcgccc gcgacggcga ggaggtcggc
     7861 gccgagcaac tcgccgagag ggcgctcggc ctcctcgggg gacgcgccga gcacggccgc
     7921 ggccacccag ccggcgaagt ccggggtgtg cagctcgctg agcaggtagt acagccgccg
     7981 ggccgagggt gacagcgccg tgtagctcaa cccgagcgag gcccgcacag tgaggtcccc
     8041 gaccgaaagc tcgtcgaggc ggcgtcgctc gtcgcgcagg aggtcggcga cgcgggcgag
     8101 tggccagtcg gggcgggagg ccagccgcgc gcccgcggcc cggaccgcga gcggcagatg
     8161 gtcgcagagc cggacgatct cggtggcctc gcccggcgcg gcccgcacct gctccggccc
     8221 cgtgatccgg gcaagcagct cgaccgcctg ggcaggccgg aacacgtcca ggcgcaggtg
     8281 ccgcacgccc gccaggcccg tcagccgggg acggccggtg atcagcacgc cgcaggcgcc
     8341 cgatcccggc agcaaggggc cgacctgggc ttctccggcc acgttgtcga tcacgacgag
     8401 catccgcctg ccggcgagga gcgaccggta gagggccgtg cggtcgccga tcgactcggg
     8461 gacggcggat ccgccgacgc cgagggcgcg cagcatcgac tccagggccc ggttcacggc
     8521 ggcgcggtcg tcggtggcgt ggtggtcggc ggcgtgatcg gcggcgtgat cggcggcgga
     8581 gaagccgacg tagagctgcc cgtcggggaa ctcgcccgcg accagatgcg ccacgcgcag
     8641 ggcgagggtg gtcttgccca ccccgcccat gccggagatc gcgcagatcg ccggcgcctg
     8701 gccgccgccg ggagacagcg cgtccctgag cgtcgcgacc tcgtcgtccc tgccggtgaa
     8761 gtcggcgatc gtgggcggga gctggcgagg gatcacggcg cctccggccg gccactcacc
     8821 cgctctcccg ggcgggtcgg tccgctcgtc gccacggagg atcgcctcgt gcgcgcggcg
     8881 caggacgggg ctcggctcga gccccagctc gtcggcgagc aggccgcgga cggcggcgta
     8941 ggtctccagg gcctcggtct gccggccgga ccggtagagg gcgagcatga ggtgcgcgtg
     9001 caggccctcc tggtaggggt gggactgcgc caccgcgcgc aactcggcca ccgcctccgc
     9061 gtgccggccg agggccagct cggtctccgc ccaccgctcg tagacggtga gccggagttg
     9121 ttcgagggac agcgcctcct ccgcgagcgg gccggaatcg aggaactccc cgaacgcggg
     9181 cccccgccac aggtccagcg cacgccggaa acagcgaccg gcggattcgt ggtcccgcct
     9241 gtcgagcgcc gccgacccct ccgccgcgag ccctctgaac cgcgccgcgt ccacctcgcc
     9301 gtgcgcgagg agcaggtatc cgtccggctt gctcagcagt cgctccgcgc ccagctggac
     9361 gcgcaactga tggacgtacg actggaggtt gctgcgggca gagaccggcg gccggtcacc
     9421 ccacagcacc gtggtcagga agtcgccgga gacggtctgg tcggcccgcg cgacgagacc
     9481 ggcgagcagc gtgcgcagct tcctggcgct gccgacgaag acgggcctgc cgtcgcggat
     9541 cacctggatc gggcccagga cctcgaaccg catccagtgt cgctccgccc cgcacagcca
     9601 cagagatcgc cgggccgtgg cgggccgcac ggtcatgctc actgagcggc gcggctcggc
     9661 gggccagcgt gttgatctta ggtcgtcgcc gcggcagggc gcaaaaggtc tccgttctgc
     9721 gcgacgtgac gactacgtac ggcgatgtag tgcggccatg gcggcggttc gtatgttttt
     9781 ggacatcctg cggaatgcat ttccgaaagc gccaaacgcc agggaggtga ccatggagaa
     9841 gcagaagagc gagcccaaga agctggagct caaggttcgc aagctggaga agatcgagac
     9901 gaccaagctc cgtgagggca gcggctgacc tgggccgacg cgccggagcc gatcgagcgg
     9961 cgatcggctc cggcgtttca cgtgacgaaa gagtgcgcgc atgcggaaac ctcgtgtcaa
    10021 acgcgttcat ctgccgaccg tcctccccga cggccggata aggatcggcc tcggtcaata
    10081 cggcgtggcc gcggaactgc aggacgacgc cgaggggaac atcgcgcgga tcctcaccct
    10141 catggacggc acccgcgacg tcgagcggat ctgcgccgac ttcgtggcgg acagcccgga
    10201 gttcgacggg gagaacgtcc gcgagatcgt cgaggcgctc gtcgccgagg ggttcgtcga
    10261 ggacgccggg gcggcgcccc ccgccaacct ctccgcacgg gagctggaga ggtacgaacc
    10321 ggcccgccac ttcttctcct gggtcgacac cgtgccccgg gagtcgccgt acaccgtcca
    10381 gtcgcggatc aagcaggcca gggtgaccgt gctcggggtg ggcggcaccg ggtccgccgt
    10441 cgcggcgggg ctggtggcga gcggcatcgg cgccctgcac gtggcggact tcgacgaggt
    10501 ccaggagtcc aacctgaccc ggcagctcct ctacaccgag caggacgtcg gcgggtccaa
    10561 ggtcgagcgg gccgtcgccc ggctgcgcgc gatgaacggc ctggtcacgg tgacgggcag
    10621 cgacgtcaag gcgaccgggg ccgacgacgt ggccgcgttg atggccggct gcgacgtgtt
    10681 cgtgctctgc gcggacgagc cccagccgga catcatgctc tggacgaacg aggcggcgct
    10741 gcgtacggga actccgtggt tcgtcagttt ctacgccggg ccgatggcgg tggtgggctc
    10801 attccacccc ggcgagacgg gatgctggct ctgcatgcgc cgtgacgagg acgccaggga
    10861 gggcgcactg ggggagcgcc cgctcgtcgc cgggcacggc cggccgaacg cggtggtcgc
    10921 cgccagcgcc aacatcagcg gtcacctgtg cgcccttgag gtgacgtacc acctcggcgg
    10981 cctgcggacc caggcgcgcg gacggatctt ccactggaac ttcgcggtct gggaccacgt
    11041 ctacgccctg gacgtgccgc gccacgacga ctgtcccgcc tgcggctcgg tgcgcggatg
    11101 acggtgcgcg gatgacggag cccgtcgcgg tcggcccggc cggcacgctc ctgctgcgcc
    11161 cgctcagcgt ccaggcggac gacgacccgg acagcgtcat cgtcgggcgg ccggagctcg
    11221 gcgagttcgt cagcctgccc gcgctctacg gcagggcgat cgagctgctc ggagacggcc
    11281 tcacagtcgg cgaggtccag cgccggatcg aggacgagca cgacgtcgaa ctggacgtcg
    11341 tggggctcgt ggaggcgctc gtcggcctcg gcttcgtcgc acggctggac ggcgcggacc
    11401 tgccggaccc ggcggacgcg gctccgccgc cccacctgcc ctggctggcg gaccggcacg
    11461 tgaggtggct cttcggccgt cccatggcgg tgctctgcgc ggtcgtggtc gtcgcggcgc
    11521 tcgtcaccct ggtcgaccgg cccgatctgg tgcccgtcta ccacgacttc ttctggagcg
    11581 actacatcgg gctcacgacg ctggtcaaca ccgcgatgtt ctcggtggtg atcagcctgc
    11641 acgagctgat gcacctggcg gccgcgcggt ctctcggcac tccggcgcgc atcgggctgg
    11701 gcacccgtct gcacaacctg gtcgtgcaga cggacgtcac cgcgatctgg tcggtgccga
    11761 ggcgctcgcg ttaccgcgtc tacctcgccg ggaccttctg cgacctcttc ctcctggcgg
    11821 ccctgctgct cgtgctcgcc cacgcgaacc cgccggaggg ggtcgctgcg ctcctgcggg
    11881 ccctcgcgct ggtcaccatg ctgagcatgc cgatggagct gcacgtctac atgcggaccg
    11941 acttctactt cgtgctcgcc gacctcctgc gctgccgcaa cctgttcggc gacgggctcg
    12001 actacgcgcg ctacctgctc cgccgcgtgg tcgcagtcgc gaggcgggca cggcctcccg
    12061 ccgacccgag cgccgaactg tccgcccacg aacggcgggc ggtgcggatc tacgcggtgc
    12121 tgctcgtccc cgccgcgacg gtcgccctcg gcatgttcgc gatctacacc ctgccgatcg
    12181 tcgccggctc gctgatcctg gcgctggccg ccgtctgggg cggcctgaac ggcggccccg
    12241 tgctgcaggg cgtcgacggc ggcctcttcc tgctcgtcga gggcgggatc cacacgctct
    12301 tcgtggtcac cttcgtccgg tcgcatcccc actggttccg ccgccggagg cccggagcgc
    12361 cggccgtacg gtgaccggcc gtgtacgcgc gtcgcccgtg ctcagtcgca gcgggtgccc
    12421 ttggccggaa ccgtcccctc cagcaggtac gcgtcgacct tgtcgttgat gcacttgctc
    12481 tggccgtacg cgccgtggcc ctcgccgttc agcgtcagca gcacgccggt gcgcagttgc
    12541 tcggtcagcc gtggcgccca ctggtagggc gtggccgggt cgttcgtgac gccgaccacc
    12601 aggatgggat tggacccggt ggcgtcgatg tgcctggcgg cgtcgtcccc gcgcaccggc
    12661 cagacgctgc acgaccccgc gctgatcgcg gtcggcccga agatcggggt ctgcttctcc
    12721 agccgcctgg ccagttcctc gccctgggcg acggagggcc ggtcggtgct gtcgacgcac
    12781 agcacggagg gcagcgagaa ctgcagggtc gagtaggtgc cgtccggctg ccgcccggcg
    12841 tactggtcgg ccagcgcgag caggccgtcg agcttgccct tcctgccctc gtccagggcc
    12901 tcggtcagca gcggccaggt gaacttgctg tagagcgcct gggtgatgcc ggccctggcg
    12961 acgtcctcgg tgaccgggcg cgagcccacc ttgcccggcg tgcgggcgag ggtgtcgagg
    13021 agcttcagca cggtggcgtt ggcggcggcg gggtcggcgc cgagcgggca actcgtcggc
    13081 gtcttggcgc agtcggccag atagtcctcg tacgccttct ggaagccgag ggcctgcgtc
    13141 ttggccattt ccagcatgtc gatcgagggg tcgacggcgg agtcgagcac catccgcccc
    13201 accttcttcg ggaactgcgt ggcgtacacc gcgccgaggt gggtcccgta ggagaagccg
    13261 aggtagttga ggttcggctc gccgagtgcc ccgcgcagta gctccagatc gcgtgccacg
    13321 ttgacggtgc cgacataggg caggatccag cccgcgttgc gctcgcaccc ccgggcgaac
    13381 tcggtcacga gcttggtctc ggtggcggtg ttctcgctgg gctccctggt catgtactgg
    13441 tccatctgcg gcccgctgag acagcggatg ccgctgctgc gctccacgcc gcgcgggtcg
    13501 aagctgacca ggtcgtagcg ggtgttgagg gtggagaacg cgtgggccgc gttcatgagc
    13561 gtcgtgacgc ccgagccgcc cggcccgccg aagttgaata ccagggagcc gatccgccgg
    13621 ctctggtcgg tggcgcgcag ccggatcagg gcgatgccga tctgcctgcc ctccggcttg
    13681 gcgtagtcga gcggcacctg aagcgtggcg cactcgaagc cggaggagga ggcggtctcc
    13741 tcgcacgcct tccactgcag ggacggcgta gccgtgacgt actcctccgg gaccacccgc
    13801 gcgccgccgc agccggcggt cgccgccagc gcgccgagcc ccgccaccgt cgccgccacg
    13861 accggccaga tcctgcgggc cgacacccct cgcgacactg aaacccctcg tgttggactg
    13921 tattcggagg gtgtctcgtt tatatcgcag accggtgcgg tggtgacgcc gacgcaccgg
    13981 aactccgcct taccggacaa tagtctaaac catttccgct cagcaggcga tgggtctacg
    14041 cggaacgcat ggagacaaat tggtttatac cagtccgcac cctcgcgaag attggccgat
    14101 ctttgattgg attagacctc tgacaggcct tctacctgct tagacgccat atgtggtgaa
    14161 gggtgatgtt tggtgctgct tttcctaggt acagtcccgg ttgcgggccg cgtccgcggt
    14221 ttctttgaag tcggcgaagg agcgtcacat gcccaagtac gtttgcgact tcaccgaggg
    14281 caacaaggac ctcaaagacc tcctcggtgg taagggcgcc aatctggcgg aaatgaccaa
    14341 catcggcctt cctgttcctc ccggcttcac gatcaccacc gaggcgtgcc gtcactacct
    14401 caggcacggc ggcatgcccg atggactgga cgcggagatc ggcgagcacc tcgccgtcct
    14461 ggaggcgcgg atgggcaagc gtctcggcca gtcggacgac ccgctgctcg tcagcgtgcg
    14521 ttcgggggcc aagttctcga tgcccggcat gatggagacg gtcctcaaca tcggcctcaa
    14581 cgacgactcg gtgctcgggc tggccaagca gtcgggcaac gaccgcttcg cgtgggactc
    14641 ctaccgccgg ctcatccaga tgttcggcaa gaccgtcctg gacatcgacg gcgagctgtt
    14701 cgaggacgcg atggacgacc tcaaggccgg gcgggaggac accgacctcg acgcctccga
    14761 cctccagcgg ctggtcgaga ccttcaagga catcgtccgc gaccggacgg gccgcgactt
    14821 ccccgccgac ccccgcgagc agatggacct cgccgtcagg gcggtcttcg actcctggaa
    14881 cgccccgcgc gcggtcctct accgccgtca ggagcgcatc cccgcggacc tcggcacggc
    14941 cgtcaacgtc gtcgccatgg tgttcggcaa cctgggcgcc gactccggca ccggtgtcgc
    15001 cttcacccgc gaccccggct cgggacgcca gggcgtctac ggcgactacc tgcgcaacgc
    15061 ccagggcgag gacgtcgtcg cgggcatccg caacaccgtc cccctccagg agctggagac
    15121 catcaacccc gcggcctacc gcgagctcct cgacatcatg gcgacgctgg agcggcacta
    15181 ccgcgacctg tgcgacatcg agttcacgat cgagcgcggc aagctgtgga tgctgcagac
    15241 ccgcgtcggc aagcgcacgg ccgaggccgc cttctgcatc gcgacccagc tcgtggacga
    15301 gggcctgatc gacatggacg aggccgtgac ccgggtcacg ggcgaccagc tcgcccagct
    15361 catgttcccg cgcttcgccg cgacggaggg tggtcgcagg ctggccaccg gcatgaacgc
    15421 gtcccccggc gcggccgtcg gcaaggccgt cttcagctcg gagcgggccg tcgagcttgc
    15481 cgggcagggc gaggcggtca tcctggtgcg gcgggagacc aaccccgacg acctcgccgg
    15541 gatgatcgcg gccaagggcg tgctcacctc caggggcggc aagacctcgc acgccgcggt
    15601 ggtggcgcgc ggcatgggca agacctgcgt gtgcggggcg gaggagcttg aggtggacac
    15661 gcgcgcccgc cgcttcaccg cgccctgcgg gaccgtcgtg aacgagggcg acgtgatctc
    15721 gatcgacggc ggcaccggcg ccgtctacct cggcgaggtc cccgtcaccg cctcgccggt
    15781 cgccaagtac ttcgagggcg agccgtccga ggacgagctg gccgaggacg agctggtacg
    15841 ggccgtcgac cgcatcatga cccacgccga ctccgtgcgc aggctcgccg tacgggccaa
    15901 cgccgacact cccgaggacg ccgcccgcgc ccgccgctac ggcgcgcagg gcatcgggct
    15961 gtgccgtacg gagcacatgt tcctggggga gcggcggcgg ctcgtggagg acctgatcct
    16021 ggccacgacg ccgaaggagc ggcaggtcgc gctcgaggcg ctcgaaccgc ttcagaccgg
    16081 cgacttcacc ggcatcctca cggccatgcg cgggctgccg gtgacgatcc ggctgatcga
    16141 cccgccgctg cacgagttcc tgcccgacct caccgacctc gccgtgcggg tagcgctggc
    16201 gggggacgag gcggtcgaca gggaccgcag gctcctggag gcggtcaagc ggctgcacga
    16261 gcagaacccg atgctgggcc tgcgcggcgt gcggctcggc ctgacgatcc ccgggctgtt
    16321 cgcgatgcag gtgcgggcca tcgccgccgc ggccaaactg gtcaagggcg cccgggcgga
    16381 gatcatgatc ccgctggtcg gcgcggtgca ggagctggag atcgtccggg aggaggcgga
    16441 gcgcatcctc gccgaggcgg gcgtggacgc ggccatcggc acgatgatcg aggtgccgag
    16501 ggcggcgctg acggccgggc agatcgccga ggccgcggag ttcttctcgt tcggcaccaa
    16561 cgacctcacc cagatggcct ggggcttctc ccgcgacgac gtggagagcg ccttcttcgg
    16621 caaatacctc gacctgggcg tcttcggcgt ctcgccgttc gagtcgatcg accgtgaggg
    16681 cgtcggacgc ctcatgcgga tcgcggtaga ggagggcagg cggacccggc cgggcctcaa
    16741 gatcggcatc tgcggtgagc acggcggcga ccccgcctcg atccacttct gccaggagat
    16801 cgggctcgac tacgtctcct gctcgccgtt ccggatcccg gtggcgcggc tggaggccgg
    16861 ccgcgcggcg ctgacctgcg cggaatcgga cacccgatga gttgaaattc cacagaatat
    16921 ccggactggt tgtggaatga ccaggtcgga ggacgggtgt ttcaccgggt cgcgcgacac
    16981 ggcccggtga ccgttgaagc cgcccgcctg agtgatcact ctacgtacct accgcaagga
    17041 aggacgtgga gtgagaatac gtcgccgccc gccggcgctc gcgatcgccg cggcgctgtt
    17101 gtgcatcctg cccgcgctgc tcgcggccgc ccccatgccg tcggccgtac caccgctgac
    17161 cccgcgggag gccgccgggc aggccccggc gggccgggcg gacgagcctt cgtcgtcgag
    17221 gcagtaccag gtggacggcc cggccaccgt cgcgcagcgc aacgcggtgg cccgcacggg
    17281 ggccgcgatc gacgaggtgc acggccggag cctggtcgtc accgcgacgc tccaggaggc
    17341 cgacgccatc cgccggctcg ggttccggat caccgaactg ccgcccccgg ccgagacggg
    17401 cggcccgcag accttcgact tccccacggg agactccggc taccacaacc acgccgagct
    17461 cagcgcgctg gtggaccagg tcgtcgccgc gcaccccgcg atcgcccgca ggttcagcta
    17521 cggccgctcg tacgagggcc gcgacctcat gggcgtcaag atcagcgaca acgtcgccac
    17581 cgacgagaac gagccggagg tgctgttcac cgcgcaccag cacgcgcgcg agcacctcac
    17641 cgtcgagatg gcgatctacc tgctgcgcct gttcaccgac aactacggcg gcgacgccca
    17701 gatcaccgat ctggtgaaca cgcgggagat ctggatcctg cccgacctca accccgacgg
    17761 cggcgagtac gacgtcgcca ccggctccta ccggtcctgg cgcaagaacc gccagcccaa
    17821 ctccgggacc tccagcgtcg gcaccgacct caaccgcaac tggggttacc gctggggctg
    17881 ctgcggcggc tcgtcgagca cgccgtccag cgagacctac cgcggcgccg ccgcggaatc
    17941 ggccccggag gtgcgggcgg tggccgactt cgtacgcggc cgggtggtcg gcggcgtcca
    18001 gcagatcaag gccgccatcg actggcacac ctacagcgaa ctcgtcctgt ggccgtacgg
    18061 gtacacgacg gccgacaccg gccccggcat gacgcaggac gacagggacg cgcacgccgc
    18121 gctcggccgg agcatggcgg ccaccaacgg ctacaccgcc gagcagtcga gcgacctcta
    18181 tgtcaccgac ggctcgatcg acgactggct gtggggcacc tacaagatct tcacgtacac
    18241 gttcgagatg tatcccaagg ggagcagccc cggcttctac ccgcccgacg aggtgatcga
    18301 cagggagacc tcgcgcaacc gggtcgccgc gctgctgctc gtccagaacg ccgactgcgt
    18361 ctaccgcgtc atcggcaagg agtcggcgta ctgcggcacc ggcacgccgc ccaccgtcgt
    18421 ctactccgac accttcgaga ccgcgaccgg ctggacggtg aacgcggcgg gcacggacac
    18481 cgccacctcg ggcgcgtggg agcgcgccga ccccgccgcg acctcctcca gcggggccaa
    18541 gcagctcggc accacggtca gcgggaccta cgacctggtc accggcgccg ccgccgggac
    18601 gagcgcgggg gaccgcgacg tcgacggggg agtgaccacg gtcacgtcgc cgccgatcac
    18661 gctgcccgcc tcggggacgc tcacgctgtc gttgtcctgg tatctcgccc acgggtccaa
    18721 ctcctccgcg gccgactatt tccgggtgaa ggtgatcggc ggcacgaccg gcacggtctt
    18781 cgagcaactc ggcgcggcca ccgacaggga cgccgcgtgg agcgtcgcca ccgcgtcgct
    18841 gaccgggttc gccggccaga ccgtgcggat ccagttcgag gcggccgacc tcgcgaccgc
    18901 aagcctcgtg gaggccgccg tcgacgacgt gcggatcacc aggagctaga ccggtcaccg
    18961 ggagccggac cggggtcagg cccactccca gcggatgccg cggacaccgg gccgggcccc
    19021 ggtgtccacc acgtgggcgg tcccgaacgc gtcgacgcgc agttcgccgg cgtcgcgggg
    19081 ccgcgccgcc gggtccggcg accaggtgtg gaaacaccgc acgggcagcc gcccgtcagt
    19141 gaaccgcacc tgcaccagat gctgctcgac cgggtcccgc aggcgccggt cgtacctgtc
    19201 ggccgcggcg acgtcggtca cgtactccac gacgtgggtc tcgccggtcg cgagcgggtg
    19261 cgggaagatc agctcggtca ggagcccgga gccgtcgtct ccgcccctgc ccggccggca
    19321 cccccgggtg cgcagcagcc gggtgccggg cggatgggtg acctcgtacc tgtccacacc
    19381 cggcgcggcg gcccgcagca cgacgcgggc gctcacgcgg tgccgcaggc ccgcgctcac
    19441 caccgcctgc tcgtggtggc tgagcacggt gagcgtctcc ggccgccgcc cacgcgggcg
    19501 gggcggcccg agcaggccga tcagggcgta ctcgggcagc gacaagatga cctcgagctc
    19561 cctgaccgcc gccagggagg cggcgcgctc gggccgggac cggccgcgct gccagtagct
    19621 gaggctggac atgctgacct cgaagccccg ctcgcgcagc cgcgagtgca ggcggtcgag
    19681 gctcaggccc cgcgtgcgga tggcggcccg cagggcgcgc tcgaagggcc cggacctgag
    19741 gacctccgcg agctcgtcgt ccaccaccag ggatcctccc cggaagcgcc agagcggcag
    19801 aagccgagta tcgcccgcgg ccgttcaccg gacaagaggg caatctccca tcggacaacc
    19861 agatctgtcg tgaaacccga ccttcgcggg taggctccat tccccgccgc cacggggctc
    19921 gccacaggaa aggaggacgc atggcccgct acgacgagca cgaccaggcg cggtgggtgc
    19981 cggagccccc gggcaacccc gagcggagcg cgttcgagcg cgacagggca cgcgtgctcc
    20041 acagcgcctc gctgcgcagg ctcgccgcga agacgcaggt ggtggccccc gccgactgca
    20101 ccggcctgca cagcccccgt acgcggctca cccactcgct ggagtgcgcg cagatcggca
    20161 gggagatggg caaggtcctc ggctgcgacc ccgacctggt ggagaccgcc tgcctcgccc
    20221 acgacctcgg gcatcccccg ttcggccaca acggggaggc cgccctcgac gaactggcgg
    20281 cgccgtgcgg cgggttccag ggcaacgcgc agaacctgcg cctgctcacc cggctggagg
    20341 ccaaggtgat caccgaggac ggccgcagcg ccgggctcaa cctcacccgg gcgacgctcg
    20401 actcggtgtg caaatatccc tgggccgggt cctcctgccg gatccccggc gtcccgctcg
    20461 cccgggaggg ccagccgtac tgcgtctacc ccgacgacct gccggtcttc cagtgggtgc
    20521 gggagggcgc gcccgactac gcggtcggct tcgaggcgca ggtcatggac tgggccgacg
    20581 acgtggcgta ctcggtgcac gacctggagg acgcgctgac gtgcggtcac gtcaccatgg
    20641 acgcgctgcg cgatccggag gagcggctgg aggtgtgccg tctgaccaag gagtggtacg
    20701 cgcccgacgc cgctatcgag gagctgtcgg agaccttcgc ccggctgatc gccgagccgc
    20761 tgtggccggc cgcctatgac gccgggcccg ccgacctcgc cgcgctcaag cggctcacca
    20821 gcgcgctcat cggcaggctg tgccgctcgg cgcaggacgc cacccgcgag gcgtacggct
    20881 gccgccccgc cccggccgca cgcggcgccg cgcccgggcg gtacggcgcg catctcgtgg
    20941 tgccgaggcc gaccaggctg gagtgcgcgc tgctcaaggg cgtgacggcc tgctacgtga
    21001 tgtcgcggga ggaccaccac gccgtccagg cccgccagcg ggagatcatc gccgagctgg
    21061 gcgacctcat cctgcggggc gccccggcga ccctggagcc c
//
