LOCUS       NZ_JABBGE010000020     19124 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. R302 contig20, whole genome shotgun sequence.
ACCESSION   NZ_JABBGE010000020
VERSION     NZ_JABBGE010000020.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. R302
  ORGANISM  Streptomyces sp. R302
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 19124)
  AUTHORS   Dahal,R.H.
  TITLE     Streptomyces sp. R302 sp. nov., isolated from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19124)
  AUTHORS   Dahal,R.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) Life Science, Kyonggi University, Kyonggi
            University, Suwon, Gyeonggi-Do 16227, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2020
            Assembly Method                   :: SPAdes v. APR-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012927245.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 03:52:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,357
            CDSs (total)                      :: 7,271
            Genes (coding)                    :: 7,075
            CDSs (with protein)               :: 7,075
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 84 of 196
            Pseudo Genes (incomplete)         :: 164 of 196
            Pseudo Genes (internal stop)      :: 20 of 196
            Pseudo Genes (multiple problems)  :: 67 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 19124
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBGE010000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..19124
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..19124
                     /SMILES="C(C)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..19124
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<4:4616](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <5..4616
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..19124
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<4:4616](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      <5..4616
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            <1..4616
                     /locus_tag="HHL19_RS36500"
                     /old_locus_tag="HHL19_36510"
     source          1..19124
                     /collection_date="2016-08"
                     /country="South Korea: Suwon"
                     /db_xref="taxon:2728844"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. R302"
                     /strain="R302"
                     /submitter_seqid="contig20"
     CDS             <5..4616
                     /NRPS_PKS="Domain: PKS_PP (137-216). E-value: 1.4e-18.
                     Score: 59.0. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36500_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (252-679). E-value:
                     1.1e-165. Score: 543.6. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36500_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (780-1076). E-value: 3.8e-97.
                     Score: 317.2. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36500_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_PP (1150-1228). E-value: 1.1e-23.
                     Score: 75.4. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36500_PKS_PP.2"
                     /NRPS_PKS="Domain: Thioesterase (1302-1509). E-value:
                     6e-30. Score: 97.3. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36500_Thioesterase.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="HHL19_RS36500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36510"
                     /product="type I polyketide synthase"
                     /protein_id="WP_169094735.1"
                     /sec_met_domain="AMP-binding (E-value: 8.2e-08, bitscore:
                     21.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.5e-197, bitscore:
                     645.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2.5e-89, bitscore:
                     289.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-97, bitscore: 317.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.5e-14, bitscore:
                     42.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.2e-24, bitscore:
                     77.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GDRASRLPDGTFAFHGRAAEVINVGGRKFSASTVEGLLGGLPQLA
                     DAAVVPRPDGRLGQYPCLVAVLRPGAVLDLAAVRAHLSAEGLAEYQQPLDLVVVERLPL
                     TPTGKVARGRLAALLDAAAALPSTDAGQWRARLAAEQAPAGLELIHRHLAELLPGHTAG
                     AGSRGRTFQDLGVDSLGAVRLALALARSSRLALPTTAVFDHPTPDALARHLASLASAHS
                     DQAPGDGRGRTPGAASGTARPQKAGERDDPVVIVGMGCRFSGGVTTPEDLWELLVAGTD
                     TGGPFPTSRGWDLARLRHPDPAHPGRAAAHRGHFLTGAGRFDAPFFGLSPHEALAMDPQ
                     QRLLLETSWEALERAGLDPTALRGSDTGVFVGLMPNDYAPRRADGPELPDGLLLTGNAP
                     SVASGRISYTLGLTGPALTVDTACSSSLVAVHLAAQSLRRDECSLALAAGATVMASPAA
                     FVGFGRAGILAPDGRCKAFAADADGTAWGEGVAVLVLERLSRAERHGHPVLAVLAASAV
                     NQDGASNGLTAPSGIAQQQLIRRALVEAKLEPGQIDVVETHGTGTALGDRIEAEALLAV
                     FGPGRDPARPLRLGAVKANIGHTQAAAGLAGVIKTVLALRHGRLPGTPRPQAFRPKAFR
                     PLGDALRLPERSEPWPPSHRVRRAGVSAFGLSGTNAHVILQEAPKARPRPAPGVEDERP
                     APWTPWVLSARSAPALREFAARLVPLTADPGVPRALAATRATLEHRAVVIARGHLDAAA
                     GLRSIADGTPSADAVTAPARSAGRTVFVFPGQGGQWPGMAAALLDESAVFADAMAACDE
                     ALAPYVDWSVRTVLRGADGRPGPERVEVTQTCLFAVTVALAELWAHLGVRPHAVVGHCQ
                     GEIAAAHVCGALSLKDAARAAARRAAAVAALPAGRMAAVALARDELDRRLVPYQGQVWL
                     AADNGPRSTVAAGTPEAVNRLVADLDARAVRASLLSVGYASHGPATEPAKAGLTSGLDE
                     LRPRPAKVPFYSALTAGRLDTTALTADYWYRSLRHPVEFRSTIRALLDAGYRDFIEIGP
                     HPVLGHAVVETAEQTDRTATAVGTLRRGEGGLRRFLLSAAQVHTQGTPVSWANVFTGRQ
                     AKHSDLPTHPFQHEHYWLPAHPTPPEPRQETADTVAAHMPVPVRHAGTDLLALVLGQAA
                     AVLGHRDATRIPPDETFTALGATSLMAVELRTRLADLLHLPLPATVALDHRTPRALADH
                     LRSLRQDPVAPRSTPDPRREPPHTLDALYRYACRTGRGEVAAELIGAASELRPTFTAAR
                     AAHHAPGTTLLAPATTRPTLLCFPSLLPASGAHEYVPLIEALRGTRGVEVLPHPGTEAD
                     QPLPADLDALTGAHAAALQRHAPLGPFLLCGHSSGGLVAHAVAARLEQLGRPAHGLVLV
                     DTPWPDHTLRRLLPRVLEHAGRALGPCDPGRLTATGAYLRLLAGRRPTPVTTPTLLLRA
                     QQPTGLLAGHGLTLTPWQLPHTPVDVPGDHFTLLTRHAPAVAEAIGSWDPAPQLPAAAS
                     RRAARPSHAPGAHGAAQ"
     aSDomain        417..653
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36500_PKS_PP.1"
                     /evalue="1.40E-18"
                     /label="HHL19_RS36500_PKS_PP.1"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="216"
                     /protein_start="137"
                     /score="59.0"
                     /tool="antismash"
                     /translation="AAEQAPAGLELIHRHLAELLPGHTAGAGSRGRTFQDLGVDSLGAV
                     RLALALARSSRLALPTTAVFDHPTPDALARHLAS"
     aSDomain        762..2042
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36500_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.10E-165"
                     /label="HHL19_RS36500_PKS_KS.1"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="679"
                     /protein_start="252"
                     /score="543.6"
                     /tool="antismash"
                     /translation="VVIVGMGCRFSGGVTTPEDLWELLVAGTDTGGPFPTSRGWDLARL
                     RHPDPAHPGRAAAHRGHFLTGAGRFDAPFFGLSPHEALAMDPQQRLLLETSWEALERAG
                     LDPTALRGSDTGVFVGLMPNDYAPRRADGPELPDGLLLTGNAPSVASGRISYTLGLTGP
                     ALTVDTACSSSLVAVHLAAQSLRRDECSLALAAGATVMASPAAFVGFGRAGILAPDGRC
                     KAFAADADGTAWGEGVAVLVLERLSRAERHGHPVLAVLAASAVNQDGASNGLTAPSGIA
                     QQQLIRRALVEAKLEPGQIDVVETHGTGTALGDRIEAEALLAVFGPGRDPARPLRLGAV
                     KANIGHTQAAAGLAGVIKTVLALRHGRLPGTPRPQAFRPKAFRPLGDALRLPERSEPWP
                     PSHRVRRAGVSAFGLSGTNAHVILQEAP"
     aSModule        762..4532
                     /complete
                     /domains="nrpspksdomains_HHL19_RS36500_PKS_KS.1"
                     /domains="nrpspksdomains_HHL19_RS36500_PKS_AT.1"
                     /domains="nrpspksdomains_HHL19_RS36500_PKS_PP.2"
                     /domains="nrpspksdomains_HHL19_RS36500_Thioesterase.1"
                     /final_module
                     /locus_tags="HHL19_RS36500"
                     /monomer_pairings="mmal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1245..1292
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0001"
                     /evalue="7.90E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="429"
                     /protein_start="413"
                     /score="20.9"
                     /tool="antismash"
                     /translation="GPALTVDTACSSSLVA"
     CDS_motif       1668..1712
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0002"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="569"
                     /protein_start="554"
                     /score="10.7"
                     /tool="antismash"
                     /translation="VETHGTGTALGDRIE"
     CDS_motif       1773..1817
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0003"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="604"
                     /protein_start="589"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GAVKANIGHTQAAAG"
     CDS_motif       2244..2267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0004"
                     /evalue="5.00E+01"
                     /label="PKSI-KS_m6"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="754"
                     /protein_start="746"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="GHLDAAAG"
     CDS_motif       2340..2396
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0005"
                     /evalue="1.60E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="797"
                     /protein_start="778"
                     /score="26.3"
                     /tool="antismash"
                     /translation="VFVFPGQGGQWPGMAAALL"
     aSDomain        2346..3233
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: False, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36500_PKS_AT.1"
                     /evalue="3.80E-97"
                     /label="HHL19_RS36500_PKS_AT.1"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="1076"
                     /protein_start="780"
                     /score="317.2"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGGQWPGMAAALLDESAVFADAMAACDEALAPYVDWSVRTV
                     LRGADGRPGPERVEVTQTCLFAVTVALAELWAHLGVRPHAVVGHCQGEIAAAHVCGALS
                     LKDAARAAARRAAAVAALPAGRMAAVALARDELDRRLVPYQGQVWLAADNGPRSTVAAG
                     TPEAVNRLVADLDARAVRASLLSVGYASHGPATEPAKAGLTSGLDELRPRPAKVPFYSA
                     LTAGRLDTTALTADYWYRSLRHPVEFRSTIRALLDAGYRDFIEIGPHPVLGHAVVETAE
                     QTDRTATAVGTLRRG"
     CDS_motif       2511..2576
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0006"
                     /evalue="3.60E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="857"
                     /protein_start="835"
                     /score="19.8"
                     /tool="antismash"
                     /translation="ERVEVTQTCLFAVTVALAELWA"
     CDS_motif       2583..2693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0007"
                     /evalue="1.50E-15"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="896"
                     /protein_start="859"
                     /score="49.2"
                     /tool="antismash"
                     /translation="GVRPHAVVGHCQGEIAAAHVCGALSLKDAARAAARRA"
     CDS_motif       2796..2834
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0008"
                     /evalue="3.50E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="943"
                     /protein_start="930"
                     /score="10.7"
                     /tool="antismash"
                     /translation="AADNGPRSTVAAG"
     CDS_motif       3042..3089
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0009"
                     /evalue="1.10E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="1028"
                     /protein_start="1012"
                     /score="11.6"
                     /tool="antismash"
                     /translation="LTADYWYRSLRHPVEF"
     aSDomain        3456..3689
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36500_PKS_PP.2"
                     /evalue="1.10E-23"
                     /label="HHL19_RS36500_PKS_PP.2"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="1228"
                     /protein_start="1150"
                     /score="75.4"
                     /tool="antismash"
                     /translation="RHAGTDLLALVLGQAAAVLGHRDATRIPPDETFTALGATSLMAVE
                     LRTRLADLLHLPLPATVALDHRTPRALADHLRS"
     aSDomain        3912..4532
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36500_Thioesterase.1"
                     /evalue="6.00E-30"
                     /label="HHL19_RS36500_Thioesterase.1"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="1509"
                     /protein_start="1302"
                     /score="97.3"
                     /tool="antismash"
                     /translation="TLLCFPSLLPASGAHEYVPLIEALRGTRGVEVLPHPGTEADQPLP
                     ADLDALTGAHAAALQRHAPLGPFLLCGHSSGGLVAHAVAARLEQLGRPAHGLVLVDTPW
                     PDHTLRRLLPRVLEHAGRALGPCDPGRLTATGAYLRLLAGRRPTPVTTPTLLLRAQQPT
                     GLLAGHGLTLTPWQLPHTPVDVPGDHFTLLTRHAPAVAEAIGSW"
     CDS_motif       4101..4172
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36500_0010"
                     /evalue="8.10E-09"
                     /label="NRPS-te1"
                     /locus_tag="HHL19_RS36500"
                     /protein_end="1389"
                     /protein_start="1365"
                     /score="27.9"
                     /tool="antismash"
                     /translation="PLGPFLLCGHSSGGLVAHAVAARL"
     gene            4613..6358
                     /locus_tag="HHL19_RS38660"
                     /old_locus_tag="HHL19_36515"
     CDS             4613..6358
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_function="GO:0003997 - acyl-CoA oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013883.4"
                     /locus_tag="HHL19_RS38660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36515"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_169094736.1"
                     /transl_table=11
                     /translation="MTTTTPADSDLTTLFTVPVPAPAVDRQESAEVYADLRRLQVRLGE
                     KRPLITDPARLRSLLELCAISDPRLFHAMFLHHCMTIGTALDKGAAPQDIAALASGEWI
                     GAALMNETGCGNSSTTVRTEARYDPATGDFVLHTPDPAAAKGPANVGLDAVARLAVVSA
                     RLLTGGTDRGTALFLVALRDGNGPCPGIAIEPLPPTAPLPLDYATVRFDHVRVPRARWL
                     ADGARISADGSFHDPLGTADARTRRSLDMARFCWGAVSAGLAAAARAGTALALAHARRR
                     TTADRLAGPTVALDHLNQQRLLFGATAQALAATTVARRATHRSWHIPPGGGHGNGPAGS
                     VLRELALAKVTAGTLSEAALTRCRSAAGAAALFSLGRVSNYQAFAQVFTSAGGDNRMLL
                     LDAAWTMATKKDYRPPDETSAPDDHIRLLRARERLLHRELTAHLAGPAGTAPDFDTWNR
                     RTGTAEHFALAHTARTTAETLHEKWRISAPGPARTPGLLAELYHLHCLEQIDAHSGWYL
                     AQGLLTTRHVLALPRQADETCRRLAPHAGALTELLEVPSPLLDGPLRPIGPSRTPTPAG
                     RREST"
     gene            6998..7303
                     /locus_tag="HHL19_RS36510"
                     /old_locus_tag="HHL19_36520"
     CDS             6998..7303
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS36510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_36520"
                     /product="hypothetical protein"
                     /protein_id="WP_169094737.1"
                     /transl_table=11
                     /translation="MWRGLTPHPRILGDRTIVAVGGTPGDKSVAYPVEDSSFDSTTSLI
                     NWVPDVRHPSSVIRHLTNSIPWAAASALPRLVPHSPMGTCGAALLQTEPRTRLWLR"
     gene            complement(7433..8014)
                     /locus_tag="HHL19_RS36515"
                     /old_locus_tag="HHL19_36525"
     CDS             complement(7433..8014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004920864.1"
                     /locus_tag="HHL19_RS36515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36525"
                     /product="suppressor of fused domain protein"
                     /protein_id="WP_169094738.1"
                     /transl_table=11
                     /translation="MCENERNQRAMAGVEAHVREFFTGHMITVSDYDLGPERREAVPDL
                     RILTVSPGPRADSWAYITAGCWSTVERDGHGLEFVLTAPVRDERFADLLAMTASYHSDH
                     HLDLEHSLPIGEPWLPGSHCDHLLVTLPYLHGPDLEQCPLPDGDARILWALPVTAAETA
                     YRREHGHEALERLFDEHAIVPTDPRRPSVV"
     misc_feature    8017..8030
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            complement(<8115..>8288)
                     /locus_tag="HHL19_RS36520"
                     /old_locus_tag="HHL19_36530"
                     /pseudo=""
     CDS             complement(<8115..8288)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004993522.1"
                     /locus_tag="HHL19_RS36520"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HHL19_36530"
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MERNSVAIASHESFGGWTETFTGPRLGAAIVDRLAFGGTVIETGT
                     DSCRLAGTRARAE"
     misc_feature    complement(8401..8415)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    9277..9291
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.15"
                     /tool="antismash"
     misc_feature    complement(9278..9293)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.57"
                     /tool="antismash"
     misc_feature    complement(9279..9290)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.42"
                     /tool="antismash"
     gene            9476..11842
                     /locus_tag="HHL19_RS36530"
                     /old_locus_tag="HHL19_36540"
     CDS             9476..11842
                     /NRPS_PKS="Domain: AMP-binding (35-415). E-value: 1e-79.
                     Score: 260.0. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36530_AMP-binding.1"
                     /NRPS_PKS="Domain: PKS_KR (528-688). E-value: 1.1e-07.
                     Score: 23.9. Matches aSDomain:
                     nrpspksdomains_HHL19_RS36530_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963632.1"
                     /locus_tag="HHL19_RS36530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36540"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_169094739.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-84, bitscore:
                     274.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.5e-33, bitscore:
                     105.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPQSQLALAGESAPQIPDVTLDELLLPLPSGAGDRTALIDGV
                     SGERWSHQEVRERALACAQDARDAGIEPGQRVLLALPNGVDFAAALLGLLAAGAVVSPV
                     GHRSPACELSRRAEAIGARMLVSGSRDRLSCLGAGTVGALPDIDALGSPTGLALLPWSS
                     GTTASPKPVAVTHRNAVAGLVQLAAAQPLGPDDVLLGMLPFCHLFGMQYVLNHALLSGA
                     SVVLLPHWDARAALDAVSEHGVTVLHAVPPMVHDLTVAAEQAVQDGTRPWQPGRLEQIL
                     SGGAPMSLETAERCERVLGVPVDGAYGLTEVNTCHFTRRGARRRPGSSGHPVPGTEYRL
                     VAPGEPAHDVAGDWPDGTGELHLRGPQVASGYLGPDGRLVAITDSDGWLATGDLARVDA
                     DGCLYVVDRLKDVIKYNGHQISPTEVEAVLRTHPAVADAAVVPVPDRRAGQLPLACIVP
                     AAGSRLTPELDAEIKEFAAARLAPHKKPRLLREVPRIERTASGKPLRRLLTPTAPRPGA
                     ARPLDPDLTGRTVLVTGGSRGLGRALAEAFLDHGARVTITGRDRTALERVHTELAPHGD
                     LDTAAVDSTDHSALCDLADRLRVRWGGVDVLVANAGAPGPCGPAWENDPDHWWSTQQAN
                     VHGTFLTCHTFVPQLIERGGRIITVASRAGLHRWPHMSAYSVAKAAVIKFTENLAAELR
                     PHGVRAFAYHPGLLTIGMATRQLDGRPEPGSWDERIQAWYLREHAAGRTTPTALSTRGA
                     LLLAAGAADHLSGQYLTPEHPALAPAGPPAGPPAG"
     misc_feature    9554..9556
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        9581..10720
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36530_AMP-binding.1"
                     /evalue="1.00E-79"
                     /label="HHL19_RS36530_AMP-binding.1"
                     /locus_tag="HHL19_RS36530"
                     /protein_end="415"
                     /protein_start="35"
                     /score="260.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GDRTALIDGVSGERWSHQEVRERALACAQDARDAGIEPGQRVLLA
                     LPNGVDFAAALLGLLAAGAVVSPVGHRSPACELSRRAEAIGARMLVSGSRDRLSCLGAG
                     TVGALPDIDALGSPTGLALLPWSSGTTASPKPVAVTHRNAVAGLVQLAAAQPLGPDDVL
                     LGMLPFCHLFGMQYVLNHALLSGASVVLLPHWDARAALDAVSEHGVTVLHAVPPMVHDL
                     TVAAEQAVQDGTRPWQPGRLEQILSGGAPMSLETAERCERVLGVPVDGAYGLTEVNTCH
                     FTRRGARRRPGSSGHPVPGTEYRLVAPGEPAHDVAGDWPDGTGELHLRGPQVASGYLGP
                     DGRLVAITDSDGWLATGDLARVDADGCLYVVDRLKDVIKY"
     aSModule        9581..11539
                     /domains="nrpspksdomains_HHL19_RS36530_AMP-binding.1"
                     /domains="nrpspksdomains_HHL19_RS36530_PKS_KR.1"
                     /incomplete
                     /locus_tags="HHL19_RS36530"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9956..10003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36530_0001"
                     /evalue="4.80E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="HHL19_RS36530"
                     /protein_end="176"
                     /protein_start="160"
                     /score="10.1"
                     /tool="antismash"
                     /translation="WSSGTTASPKPVAVTH"
     CDS_motif       10547..10600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36530_0002"
                     /evalue="4.50E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="HHL19_RS36530"
                     /protein_end="375"
                     /protein_start="357"
                     /score="19.1"
                     /tool="antismash"
                     /translation="TGELHLRGPQVASGYLGP"
     CDS_motif       11060..11134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS36530_0003"
                     /evalue="9.30E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="HHL19_RS36530"
                     /protein_end="553"
                     /protein_start="528"
                     /score="24.7"
                     /tool="antismash"
                     /translation="TVLVTGGSRGLGRALAEAFLDHGAR"
     aSDomain        11060..11539
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS36530_PKS_KR.1"
                     /evalue="1.10E-07"
                     /label="HHL19_RS36530_PKS_KR.1"
                     /locus_tag="HHL19_RS36530"
                     /protein_end="688"
                     /protein_start="528"
                     /score="23.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVLVTGGSRGLGRALAEAFLDHGARVTITGRDRTALERVHTELAP
                     HGDLDTAAVDSTDHSALCDLADRLRVRWGGVDVLVANAGAPGPCGPAWENDPDHWWSTQ
                     QANVHGTFLTCHTFVPQLIERGGRIITVASRAGLHRWPHMSAYSVAKAAVIKFTEN"
     gene            complement(11921..12490)
                     /locus_tag="HHL19_RS36535"
                     /old_locus_tag="HHL19_36545"
     CDS             complement(11921..12490)
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345212.1"
                     /locus_tag="HHL19_RS36535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36545"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_169094740.1"
                     /transl_table=11
                     /translation="MTERDFLTAKIERGFDHLDVDGSGTLTEDDHVAMGRRVALSLGHA
                     EGSSEAERITAAYLSIWREVHLPFLPPGSQGIPKDRFVASTRALAENPATARTILGGLA
                     DTYLAIADIDQDGQISPAEFLAFQRGHFPQFTEEEADEAFARLDSDGNGMLSPEEFTSA
                     VVEFWSSSDPDAAGNWWMGRPSFSPS"
     misc_feature    complement(12569..12583)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.22"
                     /tool="antismash"
     gene            complement(13042..13245)
                     /locus_tag="HHL19_RS38000"
     CDS             complement(13042..13245)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS38000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_240982098.1"
                     /transl_table=11
                     /translation="MTTEPNAIESLSQMDIAVPSTGTPKLTFWLKVSTQESGSTAYDTL
                     KTKVNGTTLATYSNADARTGYV"
     misc_feature    complement(13234..13247)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            complement(13249..>13347)
                     /locus_tag="HHL19_RS36545"
                     /old_locus_tag="HHL19_36555"
                     /pseudo=""
     CDS             complement(13249..>13347)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005262957.1"
                     /locus_tag="HHL19_RS36545"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36555"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RLKQWRGIATRYDKTAESYEAAVALASLLMWA"
     misc_feature    complement(13902..13915)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.62"
                     /tool="antismash"
     misc_feature    13917..13930
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.04"
                     /tool="antismash"
     gene            complement(14170..14655)
                     /locus_tag="HHL19_RS36555"
                     /old_locus_tag="HHL19_36565"
     CDS             complement(14170..14655)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010275200.1"
                     /locus_tag="HHL19_RS36555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36565"
                     /product="hypothetical protein"
                     /protein_id="WP_169094741.1"
                     /transl_table=11
                     /translation="MTVFLCSKCGTAITPELAELAAVPDPSDDEHDRDKETRRAPSTVP
                     RGRYAIDPEPWGPPYVVQDDQEDPKPAQSRGPLVCREEGFVISAGVPGTVLIHPEDAPG
                     LQPLPNWENGTGCCGPTGDEGLNRACPCGAAVATLAGDCFGPYELHLDPVRTYAFSQ"
     gene            complement(14672..14920)
                     /locus_tag="HHL19_RS36560"
                     /old_locus_tag="HHL19_36570"
     CDS             complement(14672..14920)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS36560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_36570"
                     /product="hypothetical protein"
                     /protein_id="WP_206325808.1"
                     /transl_table=11
                     /translation="MSGATSMAVAAPYDRLREAQEQGWLGEVAAIEASLAAAEQELAAM
                     RDFEVRHGTVHLGMPDFRSVVARIDSEQPNEGAKQQV"
     gene            complement(14984..15529)
                     /locus_tag="HHL19_RS36565"
                     /old_locus_tag="HHL19_36575"
     CDS             complement(14984..15529)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003954532.1"
                     /locus_tag="HHL19_RS36565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36575"
                     /product="hypothetical protein"
                     /protein_id="WP_169094742.1"
                     /transl_table=11
                     /translation="MTYEELCWEPIAALPEGEPETSFGGRWEDRLWLNVPGPFYTDIAD
                     NCWTGRLHAPRHVLYGGEYFGEYVYRQPATTAEVLNLVTAAQEDPYRGYACDGDSRWTP
                     EAVRDWWRDRGRVTEYLESLLPTWSSSDRSDEREAAEGLRDFAAYITEGLGADLRKYLL
                     RLEEGCYPKNSGPLPELR"
     misc_feature    15713..15727
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     misc_feature    15800..15815
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     misc_feature    15803..15818
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.1"
                     /tool="antismash"
     gene            15857..16558
                     /locus_tag="HHL19_RS36570"
                     /old_locus_tag="HHL19_36580"
     CDS             15857..16558
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050532 - 2-phosphosulfolactate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358202.1"
                     /locus_tag="HHL19_RS36570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36580"
                     /product="2-phosphosulfolactate phosphatase"
                     /protein_id="WP_169094743.1"
                     /transl_table=11
                     /translation="MDSRFLGIPELVEAPSVAVVVDVMRAFTVAAWAFAQGAEKIVLAE
                     SLDEALALKARHQDWVALKDGPPAPGFDTVNSPGLLRSIDLGGRTVVQKTTAGTVGALA
                     VKEASLVLCASFVVAEATARLLRTRNSDSVTFVVTGEAGQADEDLACAQYIARRATETG
                     TDAAEFLRRAAESRAAAELAEGVRQGVHPDDVALCLELDRFPFAMVATSEDSLMVLRPC
                     AVPSLTDEASI"
     gene            16660..17247
                     /locus_tag="HHL19_RS36575"
                     /old_locus_tag="HHL19_36585"
     CDS             16660..17247
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS36575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_36585"
                     /product="hypothetical protein"
                     /protein_id="WP_169094744.1"
                     /transl_table=11
                     /translation="MADPSGASGGFAESNDLFVLGGEAGQGLGAEVRELVDPPLRSGEP
                     FFELDEIRSPAELTLPAVDLSEEEIERALTLLDSMTVEHLADLGDALTDHYTEALHEVI
                     EAKAEDRAPRPVEGEAAPAGQVVDLMAALEASVAEARERRGEAPAAGGGGEEATVHELP
                     RKKAPAKKAGAKKTTANKALAKKAASRRRKPA"
     gene            complement(17592..17798)
                     /locus_tag="HHL19_RS36580"
                     /old_locus_tag="HHL19_36590"
     CDS             complement(17592..17798)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063606.1"
                     /locus_tag="HHL19_RS36580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_36590"
                     /product="hypothetical protein"
                     /protein_id="WP_169094734.1"
                     /transl_table=11
                     /translation="MTSPAAPYRPSPKNMRPEMTPSDQVGLCARCHAKCHRYGPGGCPL
                     CQECQASAPAMAFTHRPPALASM"
     misc_feature    complement(17859..17874)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            <17966..>18154
                     /locus_tag="HHL19_RS36585"
                     /old_locus_tag="HHL19_36595"
                     /pseudo=""
     CDS             17966..>18154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507637.1"
                     /locus_tag="HHL19_RS36585"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HHL19_36595"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRQLLFEQLPGYTGVDVADRGADPAGEALLTVDEMEHLIATWVVA
                     VWQRRALGEFAPGWDPDG"
     misc_feature    18453..18467
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.99"
                     /tool="antismash"
ORIGIN
        1 ccggggaccg ggccagccgc ctgcccgacg gcaccttcgc cttccacgga cgcgccgccg
       61 aggtgatcaa cgtgggcggc cggaagttct ccgcctccac cgtcgagggc ctgctcggcg
      121 gcctcccgca gcttgccgac gccgccgtcg tcccccgccc ggacggccgg ctgggccagt
      181 atccgtgcct ggtcgccgtc ctgcgccctg gcgcggtcct cgatctggcg gcggtgcgcg
      241 cgcacctgtc ggccgagggc ctggccgagt atcagcagcc gctggacctg gtcgtcgtcg
      301 aacgactacc gctcaccccc accgggaagg tggcccgcgg ccggctggcc gcgctgctgg
      361 acgccgccgc ggcgctcccg tcgacggacg ccggacagtg gcgggcccgg ctggccgcag
      421 aacaggcgcc tgccggtctt gagctgatcc accggcacct cgccgaactg ctcccggggc
      481 atacggccgg ggcgggcagc cggggccgga cgttccagga cctgggggtg gactcgctcg
      541 gcgcggtgcg tctggccctg gccctggccc gttcgagtcg gctggcactg cccaccaccg
      601 cggtcttcga ccaccccacc cctgacgccc tggcccgcca cctggcctcc ctcgccagcg
      661 cccactccga tcaggccccc ggcgatggcc gcggccgcac cccgggcgcg gcgagcggca
      721 cagcccggcc gcagaaggcc ggcgagcggg acgatccggt cgtgatcgtg gggatgggct
      781 gccgcttctc cggcggcgtc accacccccg aggacctgtg ggaactcctg gtggccggca
      841 ccgacacggg cggcccgttc cccacgagcc gcggctggga cctggcacgg ctgcggcacc
      901 cggaccccgc ccaccccggc cgagctgccg cccaccgagg gcacttcctg accggcgccg
      961 gccggttcga cgccccgttc ttcggtctct ccccacacga agcactggcc atggacccgc
     1021 agcagcggct gttgttggag accagctggg aagctttgga acgcgccgga ctggacccga
     1081 ccgcactgcg cgggtccgac acgggcgtgt tcgtcggcct gatgcccaac gactacgcgc
     1141 cccggcgcgc cgacggaccc gaactccccg acggcctgct gctcaccggc aacgccccca
     1201 gcgtcgcctc cggccggatc tcctacacgc tcggcctgac cggccccgcc ctgaccgtcg
     1261 acaccgcctg ttcgtcctcc ctggtcgccg tgcacctggc cgcccagtcc ctgcgccgcg
     1321 acgagtgctc actggccctg gccgcaggag ccaccgtgat ggcctcgccg gccgctttcg
     1381 ttggcttcgg ccgggcaggg atccttgccc cggacggccg ttgcaaggcg ttcgcggccg
     1441 acgcggacgg cacggcctgg ggcgagggag tcgccgttct ggtgctggag cggctgtctc
     1501 gggccgaacg ccacggtcac ccggttctcg ccgttctggc cgcatcggct gtcaaccagg
     1561 acggcgcgag caacggcctg accgccccca gtgggatcgc ccagcagcag ctgatccgcc
     1621 gcgccctggt cgaggcgaag ctggagcccg gccagatcga cgtcgtggag acacacggca
     1681 ccggcacggc gctcggggac cggatcgagg ccgaagcgct gctcgctgtc ttcgggcccg
     1741 gccgggaccc ggcgcgtccc ctgcggctgg gcgccgtcaa ggcgaacatc ggccacaccc
     1801 aggcagccgc cggcctggcg ggcgtcatca agacggtgct ggccctgcgc cacggccgcc
     1861 tgcccggcac ccctcgcccg caagccttcc gcccaaaagc cttccgcccg ctcggcgacg
     1921 cgctccggct gccggagcgg tccgagccgt ggccaccgtc gcaccgcgta cgccgtgccg
     1981 gggtgtcggc cttcggcctc agcggcacca acgcccacgt catcctccaa gaggcaccga
     2041 aggcgagacc aagaccggca ccgggcgtgg aggacgaacg gcctgcgcca tggacgccct
     2101 gggtactctc cgcccgcagc gcccccgcac tgcgggaatt cgctgcccgt ctggtgcccc
     2161 tcaccgcaga cccgggggtt ccccgggccc tggcggccac cagggcgacg ctcgagcacc
     2221 gcgcggtcgt catcgcgcga ggacacctcg atgcggccgc cggcctgcgc tcgatcgctg
     2281 acggcacccc gtccgccgac gcggtcaccg caccggcccg atcggccggc cggaccgtgt
     2341 tcgtcttccc cggccagggc gggcagtggc cgggcatggc agccgctctc ctcgacgagt
     2401 ccgcggtgtt cgccgacgcc atggccgcct gcgacgaggc cctggcgccg tatgtcgact
     2461 ggtccgtgcg caccgtcctg cgcggggcgg acggccggcc gggcccggaa cgggtcgagg
     2521 tgacgcagac ctgcctgttc gccgtgacgg tcgcgctggc cgagctgtgg gctcacctgg
     2581 gtgtgcgccc gcacgccgtg gtcggacact gccagggcga gatcgccgcc gcccacgtct
     2641 gcggggcgct gtccctgaag gacgccgcgc gggcggcggc ccggcgggcg gcggccgtcg
     2701 cggcgctgcc cgccgggcgg atggctgccg tcgccctggc ccgtgacgaa ctcgaccgcc
     2761 ggctggtccc gtaccaagga caggtgtggc ttgccgcgga caacggcccg cgctcgaccg
     2821 tggccgccgg caccccggag gcggtgaacc ggctggtcgc tgacctcgac gcacgcgcgg
     2881 tgcgcgcgag tcttctgtcc gtcgggtacg cgtcccacgg tccggcaaca gagcccgcaa
     2941 aggccggcct gacgagcggc ctcgacgaac tgcggccccg gccggcgaag gtcccgttct
     3001 actccgccct gaccgccggc cgcctggaca ccaccgccct gaccgccgac tactggtacc
     3061 gcagcctgcg ccacccggtc gagttccgtt cgacgatccg cgctctgctc gacgcgggct
     3121 accgcgactt catcgagatc ggtccgcacc ccgtcctcgg ccacgccgtc gtggaaaccg
     3181 ccgagcagac cgaccggacg gccaccgcgg tagggaccct gcgccgcggc gagggcggtc
     3241 tgcgacgctt cctgctgtcg gcggcccagg tccacacaca gggaacgccc gtctcctggg
     3301 ccaacgtgtt caccggccgg caggcgaagc actccgacct gccgacccac ccgttccagc
     3361 acgagcacta ctggctcccc gcccacccca cgcccccaga accccgccag gagacagccg
     3421 ataccgtcgc cgcacacatg cccgtgcccg tccggcacgc cggaacggac ctgctggcgc
     3481 tggtcctcgg gcaggccgcg gccgtcctgg gccaccgcga cgccacccgc atcccgccgg
     3541 acgagacctt caccgccctg ggcgcgacct cgctgatggc cgtcgaactg cgcacccgcc
     3601 tggccgacct gctccatctc cccctgcccg caaccgtcgc cctggaccac cgcacccccc
     3661 gcgctctcgc cgaccatctg cgaagcctgc ggcaggaccc ggtcgccccc cgcagcacac
     3721 cggacccccg aagggagccg ccgcacaccc tggacgctct ctaccggtac gcctgccgaa
     3781 ccggcagggg agaagtcgca gccgagctga tcggcgcagc ctccgagctc cgccccacgt
     3841 tcacggccgc ccgcgccgcc caccacgccc ccggaacgac gcttctcgca ccggcgacca
     3901 cgcggcccac cctcctgtgc ttcccctccc tgctgcccgc ttccggggcc cacgagtacg
     3961 tgccgctcat cgaggccctg cgcggcaccc gcggggtgga ggtcctcccc caccccggta
     4021 ccgaggccga tcagccgctc cccgccgacc tcgacgccct gaccggcgca cacgcggccg
     4081 cactccagcg gcacgccccg ctcgggccgt tcctgctgtg cgggcactcc tccggcggac
     4141 tggtcgcgca cgcggtcgcg gccaggctcg agcaactcgg ccgccccgcc cacggactgg
     4201 tccttgtgga caccccctgg cccgaccaca cgctgcgccg gctcctgccc cgtgtcctgg
     4261 aacacgccgg ccgggccctc ggtccctgcg accccggccg gctcaccgcc accggtgcct
     4321 acctgcgcct gctggccgga cggcggccga cccccgtcac cacccccaca ctgctgctgc
     4381 gcgcgcaaca gcccaccggc ctcctcgccg gccacggcct gacgctcacc ccgtggcagc
     4441 tgccgcacac cccggtcgat gtccccggcg accacttcac cctcctcact cgccacgccc
     4501 cggccgtggc agaggcgatc ggaagctggg accccgcccc gcagctcccg gctgccgcat
     4561 cacgccgggc cgcccgaccg tcgcacgccc ctggggctca tggagcagca cagtgaccac
     4621 gaccaccccg gccgacagcg acctcaccac gttgttcacc gtgcccgtac cggccccggc
     4681 cgtcgaccgg caggagtccg cggaggtcta cgcggaccta cgccgtctgc aggtccgact
     4741 gggcgagaaa cggcccctga tcaccgaccc ggcccggctg cgctctctgc tggaactgtg
     4801 cgcgatcagc gacccccggc tgttccatgc gatgttcctc caccactgca tgacgatcgg
     4861 caccgccctc gacaagggcg ccgcgccaca ggacatcgcg gccctcgcct cgggcgaatg
     4921 gatcggcgcc gccctcatga acgagaccgg ctgcggcaac agcagcacta cggttcgcac
     4981 cgaggcccgc tacgaccccg caaccggcga cttcgtgctg cacaccccgg acccggcggc
     5041 ggccaaggga cccgccaacg tgggcctgga cgcagtggcc cgcctggccg tcgtcagcgc
     5101 ccggctcctc accggcggga cggaccgcgg caccgccctg ttcctcgtcg ccctgcgcga
     5161 cggcaacggc ccctgcccgg gcatcgccat cgaaccactg ccgcccaccg ccccgctgcc
     5221 cctggactac gccaccgtgc gcttcgacca cgtccgtgtc ccccgggccc gctggctcgc
     5281 cgacggcgcc cggatcagcg ccgacggatc cttccacgac ccgctgggga cggccgacgc
     5341 ccgcacccgg cgcagcctgg acatggcccg cttctgctgg ggcgcggtca gcgcgggact
     5401 cgcggccgcg gcccgggcgg gtaccgcgct cgccctcgcc cacgcccgcc ggcgcaccac
     5461 cgccgaccgc ctggcgggcc cgaccgtcgc cctggaccac ctcaaccagc aacgtctgct
     5521 gttcggcgcc accgcccaag ccctcgcggc caccaccgtc gcccgccggg ccacccaccg
     5581 cagctggcac atcccgccgg gcggcggaca cggcaacggc ccggccggat ccgtccttcg
     5641 cgaactcgcc ctggccaagg tcaccgccgg caccctctcc gaagccgcgc tgacccgctg
     5701 ccgctccgcc gccggtgccg ccgccctgtt ctcactcggc cgcgtgagca actaccaggc
     5761 gttcgcccaa gtcttcacct cggcaggcgg cgacaaccgg atgctcctgc tggacgccgc
     5821 ctggaccatg gccaccaaaa aggactaccg gccgccggac gagacctcgg cgcccgacga
     5881 ccacatccgg cttctgcggg cccgcgaacg actcctgcac cgcgaactca cggcccacct
     5941 ggccggcccc gcaggcactg cccccgactt cgacacctgg aacaggcgaa ccgggacggc
     6001 cgagcatttc gccctggccc acacggcacg caccacggcc gagacactgc acgagaaatg
     6061 gcgcatctcg gccccgggac ccgctcgaac ccccggcctg ctcgccgagc tgtaccacct
     6121 gcactgcctg gaacagatcg acgcccacag cggctggtat ctcgcccagg gcctgctcac
     6181 cacgcggcac gtactcgcgc tgccgcgtca ggccgatgag acgtgccgcc ggctagcccc
     6241 ccacgccggg gccctcaccg agcttctcga ggtgcccagt ccgctcctgg acggcccgct
     6301 ccgccctatc gggccctccc ggacaccgac accggccggc agaagggaaa gcacgtgagg
     6361 atcaccatcg tcggcacagg catcgccggg ccgacctgcg ccccgggcct tcacgccaca
     6421 ggggttcacc cccagggtgc gggaggcggc acggacgatc acagccgtcg gcgtgggcat
     6481 caacctgctg ccgcacgccg tgcgggaact ggccgaaccc ggcctcgcag acgggctcgc
     6541 ggacggcctc acggacggcc tcgcggacgg gctcgcggat gggctcgcgg atgggcttgc
     6601 ggatgggctt gcggacgggc tcgcggtcat cgcgccggcc ccaggtcgcc tcagctacca
     6661 caatcgcacg ggccatagcg tacggcagga gccgcccggt ctcgcggcgg gctgcaactg
     6721 gccgcagtac tccgtccacc gcggccacct gcacactgtg ctgctccccg ggcgctcgcg
     6781 agcgcccggg gcccggcgcc gtccgcaccg gccacaagct ctcgcacttc gagcagacat
     6841 ccgctgatgt cagggcgggc gcatttcctc gaccgcactg aaaaccgggc aacgctccgc
     6901 cgcagccgac ctgctgatcg gctgcgacgg catcgactcc gccgcacgcg cccagctcca
     6961 ccctgacgaa ggccctgctc gttggaacgg cgtccacatg tggcgcgggc tcacgccgca
     7021 cccgcgcatc ctcggcgacc gcacaatcgt cgccgtcggc ggcaccccag gcgacaagtc
     7081 cgtcgcctat ccggtcgaag actcctcctt cgacagtacg accagcctga tcaactgggt
     7141 gccggacgtc cgtcatccgt catccgtcat ccgccatctg accaactcga tcccgtgggc
     7201 cgccgcatca gccctgccca gactcgtccc gcactcaccg atggggacct gcggcgcggc
     7261 cctgctgcag accgagcctc gaactcgcct ctggcttcgc tgatgaaaac agacagcgat
     7321 cgtcgatggc tttgggcggc agtcgatgat cactgagcct cgacatgtcg acgagtttcg
     7381 acggcaccgg agggctccgt ggttgccgct tgcgtcccgg aagctcgcga agtcagacga
     7441 cggatggacg ccttgggtcg gtggggacga tcgcgtgctc gtcgaaaagc cgttcaaggg
     7501 cttcgtggcc gtgctcgcgg cggtacgccg tctcggctgc ggtgaccggc agagcccaga
     7561 ggatgcgggc atcaccgtcc ggcagtgggc actgctcgag gtcaggtccg tgaaggtagg
     7621 gaagggtgac cagaaggtgg tcgcagtggg acccgggcag ccacggctcc ccgatgggca
     7681 ggctgtgctc gaggtcgagg tggtgatcgg agtggtagga ggcggtcatg gccaaaagat
     7741 cagcgaagcg ttcgtcgcgg acgggagcgg tgaggacgaa ttcgagaccg tggccgtccc
     7801 tctcaaccgt ggaccagcag ccggcggtga tgtaggccca gctgtcggcg cgcggtcctg
     7861 ggctgacggt gaggatccgc aggtcgggaa cagcttccct gcgttcaggt cccaggtcgt
     7921 agtcgctgac cgtgatcatg tggccagtga agaactcgcg aacgtgggcc tcgacgcctg
     7981 ccatcgcccg ctggttgcgc tcgttctcgc acatgatgga gaggatctca cggctggccc
     8041 aggtgtcctg gctgtgagtc cgccccgccg caggcggggc ggactccgac ggtccagctg
     8101 gccttgaccg gcccctcggc tcgggctcgg gtgccggcga ggcggcagga gtcggtgccg
     8161 gtctcgatga cggtgccgcc gaaggcgagc cggtccacga tggccgcgcc gaggcggggg
     8221 ccggtgaagg tctcggtcca gccgccgaag gactcgtggg aggcgatggc gacgctgttc
     8281 ctctcctcgc atgcctcctg cccgcaggac gcgaacacgc ggtggacggc gtggacggcc
     8341 ctgccggaat acgacaggcg gaaggagaac aggcagcagg tcaccagctc gccggcgagg
     8401 cggaacgtca cgtcgccgac gtcgacctcc gcctcgtgac cgcgctggcg ggtctgcgcg
     8461 acgaacgcct ccagcggcgc ctcgcccgac tcgaccagaa tctcgggctt ccgcgccgcg
     8521 acgtagtaac ggaccatccc gtacgagaca ccggcgccgt gtccctcgac cagccggtgg
     8581 aagatccggg ggaccgtgtg ccgccgcttg cgcggcgcgt ccaggtccgc ccgcccacag
     8641 gatctcgtcg atcaccgact tgcagcggtc cactccggtc gcccgcggcg gcagcttctc
     8701 gcacggctcc ggccagcacg agtccaacgc cttccgcacc gcccgccacg ccacaccgtg
     8761 cttacgctca agtccccgca tcgacatgcc gccacgatcg tcacaccgga tcgccgcgta
     8821 cagctcgacc gccgacatcc gcggcatgac cagcaccctt tcaccaggag catcccggtg
     8881 ctgccctggc aagaaccctg gtgcctcccg aactcatcga caggcgacgt cacaactgct
     8941 cgacaaagcc acgcctctct catccgagga ctgcacgcgt ctcgcgcgtc agcgcgccga
     9001 ggaagacagg gcgagaggca agggacccgg gaccgctccg cagcccaccc gacacccacg
     9061 gcctcgcctc gtcacggcac cggtagctgc gccctcctgc ggtaggagcc ggcgtcagga
     9121 ctcatcgcgc tcccccctgc gggtgatctg tccgtcacag acggtccaga acgacgctgc
     9181 ggtcccctcc catcagaccc ctgccctcga cagtcgcaga cctcttcaac atcgccgtca
     9241 ggactgacgg cccatctgcg tgtacgtcga cttccttgaa aatcgtttcc tttggcggcc
     9301 tggcccgttg ggcatgacgt ggcgatcccg gcgcgcgtgg ggggggcgag gccgggagct
     9361 gctgtacata ggcgtcgagg aatcgattcg ctcgctgccc tcacggcagt gggcgcggtg
     9421 cggacggtcg agggacgccg ccaaccgccc accgttcccc gctcggaggt gccctatgtc
     9481 caccgcgccc cagtcacagc tcgccctcgc cggcgaaagc gcgccgcaga tccccgatgt
     9541 caccctcgac gagttactgc tgccactgcc gtccggcgcc ggcgaccgca ccgcgctgat
     9601 cgatggtgtc agcggggagc gctggagcca tcaggaggta cgcgagcgcg ctctggcctg
     9661 tgcgcaggac gcgcgcgacg ccggcatcga acccgggcag cgggtgctgc tcgccctgcc
     9721 caacggcgtc gacttcgcgg ccgcgctgct cgggctgctg gccgcgggcg cggtggtcag
     9781 cccggtcggc caccgttctc ccgcctgcga actctctcgc cgggccgagg cgatcggcgc
     9841 ccggatgctg gtgagcggtt caagagatcg actcagctgc cttggggccg gcaccgtcgg
     9901 cgccctgccc gacatcgacg ccctggggtc gccgaccggc cttgccttgt tgccctggtc
     9961 ctccggcacc acggcgagcc ccaagccggt cgccgtgacc catcgcaacg cggtggccgg
    10021 tctcgtccag ttggccgctg cccagccgct cgggcctgac gacgtactgc tcggcatgct
    10081 gccgttctgc catctgttcg ggatgcagta cgtcctcaac cacgcgctgt tgtccggcgc
    10141 gagcgtggtg ctgctccccc actgggatgc ccgggcggca ctggacgcgg tctcagaaca
    10201 cggcgtcacc gtgctgcatg cggttccgcc gatggtccat gacctcacgg ttgctgctga
    10261 acaggctgtg caagacggca cgcgtccctg gcagccaggg cgcctggagc agatcctcag
    10321 cggtggtgcc ccgatgtccc tggagacggc cgaacgctgc gagcgcgtgc tgggtgtgcc
    10381 agtggacggc gcgtacggac tcaccgaggt caacacctgc cacttcactc ggcgcggcgc
    10441 caggcgccgg cccggatcga gcggacaccc ggtgcccggc accgaatacc ggctggtggc
    10501 gccgggtgag cccgcacatg acgtggctgg cgactggccg gacggaaccg gcgaacttca
    10561 tctgcgcggc ccgcaggtcg cctccggcta tctcggcccg gacggccggc tggtcgcgat
    10621 caccgactcc gacggctggc tggccaccgg tgacctggcc cgggtcgatg ccgacggctg
    10681 cctgtacgtg gtcgaccggc tcaaggacgt catcaagtac aacgggcacc agatctcccc
    10741 gaccgaggtc gaagcggtgc tccgcaccca tccggcggtc gccgacgcgg ccgtcgtccc
    10801 ggtgcccgac cggcgggccg gacagctacc gctggcctgt atcgtgcccg ccgccggcag
    10861 ccgcctcacc ccggaactcg acgccgagat caaggagttc gccgcggccc ggctcgcccc
    10921 ccacaagaag ccacgtctcc tgcgggaggt cccgcgcatc gaacggaccg cctccggcaa
    10981 accgctgcgc cggctgctca cccccaccgc cccccggccg ggcgccgccc gcccgctcga
    11041 ccccgacctc accggccgga ccgtcctcgt caccggcggc tctcgcggtc tgggccgggc
    11101 tctggccgaa gccttcctcg accacggcgc ccgcgtcacg atcaccggac gcgaccggac
    11161 cgctctggag cgggtgcaca ccgaactggc cccgcacggc gacctggata ccgcggcggt
    11221 ggacagcacc gaccacagcg cactgtgcga tctcgccgac cgcctgcggg tccgatgggg
    11281 cggcgtggac gtgctggtcg ccaacgccgg agcacccggg ccctgcggcc ccgcctggga
    11341 gaacgacccc gaccactggt ggtccactca acaggccaac gtccacggca cgttcctgac
    11401 ctgccacacc ttcgtcccgc agctgatcga acgcggaggc aggatcatca ccgtggccag
    11461 ccgcgccgga ctgcaccggt ggccgcacat gtcggcctac tcggtcgcca aggccgcagt
    11521 gatcaagttc accgagaacc tggccgccga actgcgcccg cacggcgtcc gcgccttcgc
    11581 ctaccacccg gggctgctca cgatcggcat ggccacccgc caactggacg gccgtcccga
    11641 acccggatcc tgggacgaac gcatccaggc ctggtacctg cgcgaacacg ccgccggccg
    11701 gaccaccccc accgcgctca gcacccgcgg cgcgctgctg ctcgccgcgg gcgcggccga
    11761 ccacctctcc gggcagtacc tcacccccga acaccccgcc ctcgcccccg cggggccgcc
    11821 tgcggggccg cctgcggggt gatcccaccc ggccgaccgc cgagcgtccc ggccgttcgc
    11881 cccatgaggg cctcgggccg ggacgccggc ggtggggacg tcagctcggc gagaaggaag
    11941 gacgccccat ccaccagttg ccggcggcgt cggggtccga gctggaccag aactcaacca
    12001 ccgcgctggt gaactcctcg ggcgacagca tgccgttgcc gtcggagtcg aggcgggcga
    12061 acgcctcgtc ggcctcctcc tcggtgaact gcgggaagtg cccacgctgg aacgcgagga
    12121 actcagccgg gctgatctgc ccgtcctggt cgatgtccgc gatcgccagg taggtgtcgg
    12181 cgagcccgcc gaggatcgtg cgggcggtcg cggggttctc ggccagggca cgggtcgagg
    12241 cgacgaaccg gtccttggga attccctggc tgccgggcgg gaggaacggc aggtgcacct
    12301 cccgccagat gctgaggtag gcggcggtga tccgctccgc ctccgaagac ccctcggcat
    12361 ggccgagaga gagcgccacc cgacgcccca tcgccacgtg gtcgtcctcg gtgagcgtcc
    12421 cactgccatc cacgtcgagg tggtcgaaac cccgctcgat cttcgccgtc aaaaagtccc
    12481 gctcggtcat cgctgctcct cgtaagcctg cgaacacatg gacaaggcac cgaaacgcac
    12541 cctgccgtca ggccaacgac acacctcccg gaaggaaacg tccacgaccc ggccgaagcc
    12601 accagccgca actactcacc cgcgccgacg ccgcgctcca ccgctgcccc ggcccgccac
    12661 cccctcgtcc gtccacaacg gccccgctcc ctggtcaaac gcagaccgcc gtccgtctgc
    12721 cagccgatac cgaccggccg gccacactgg cgatcacact ggccatggca ctaggcagtt
    12781 caccgggaac ccgatcacga aacggcagcc acccatggga gtgaaggaca tctcgcctgt
    12841 tcgggtcacc ccgctgagcg cggcagggcc ctgtggccgg accgccccga aggtcggcca
    12901 caggagtacc ggtggcgagg gggccggtca gccgatggcg acgtcgtcga tcaggaagat
    12961 cgtcgccagg tattcgtcct cggtgccggc gaactccagc cgcaccgtcc gccccttgca
    13021 ggcggacagg ccgacggtct tctaaacgta tccggtcctc gcgtcggcgt tggagtaggt
    13081 cgccagcgtg gtgccgttga ccttggtctt gagggtgtcg taggcggtgg agccggactc
    13141 ctgggtggag accttcagcc agaaggtgag cttcggggta ccagtggagg gcaccgcgat
    13201 gtccatctgc gacagggact cgatggcgtt aggttctgtc gtcaaatgtc acgcccacat
    13261 gaggagtgag gcgagggcga cggctgcttc gtaggattca gcggtcttgt cgtacctcgt
    13321 ggcgatgccg cgccactgct tgagacgatg ggctgtcggc gcggcagcgg ccttcgtgtc
    13381 ccgccctctg atgcatggcc tttgacgaca gaccccagca acgctggtgg gcgggcaggc
    13441 ccgctcgggc ccgccagcag tccgcgtcgc gagggtcggt cagccatccg atcacccgct
    13501 cagcgcctgt ccggaaggcg ccgggcagcg agtactcctc gccgatgaca ggcctgaggg
    13561 cgtcgacgtc atgggtggca tgatcggtgt cgcaccagca ggccacgttc accgccgcgt
    13621 cgactgcgag ccggcctcgg tctgtccaca ccacctcaag ccggaactcc agctgatcgg
    13681 ccccagccgc atgctcgacg acatccaggc cgaggatgat cggcgtccac ggctgcgtgc
    13741 cggggaagac cgcgtgctgc agtgcccatt cccactccgt cccgtctccg tcggcgcaaa
    13801 ccgcatcgac ggtccgagcc gcatgcctca gggattccac gtcggcaggc gacaggaaag
    13861 ggaagagcgt ggtcaacggg acgtcgtcga aggcacctcg gttcatggcc atgcgtcgat
    13921 catccgttct ccccggcccg agcaacaagg aggcctcatt cctgaggtct ccataacgag
    13981 actgccaggt tgccgtccac caagctgagc acgttcatcc gtacctggct gagcacttca
    14041 acgagtacgg cgacagctcg acacttggct cgtcatcgaa gtgccttcgc aacggaaagc
    14101 agtcgtgaag tcgccggatc aagaggccgt cccgggcgtg tcgcgctccg gggcggccgt
    14161 ccagcgtgcc tactgggaga acgcgtaggt tcggacagga tcgaggtgca gttcgtaggg
    14221 cccgaagcag tcccccgcga gcgtcgcgac cgcagcgccg cagggacagg ctcggttgag
    14281 tccttcgtca cccgtcggcc cacagcagcc ggtgccgttc tcccagttag gcagcggttg
    14341 aaggccgggg gcgtcctccg ggtgtatcag caccgtgcct ggcacacccg ccgagatgac
    14401 gaagccctcc tcgcggcaga ccaacggccc tcgggactga gccggcttcg ggtcctcctg
    14461 atcgtcctgc acgacgtagg gaggtcccca gggctcggga tcgatcgcgt agcggccccg
    14521 cggaacggtg gagggggccc ggcgtgtctc cttgtcccgg tcgtgttcgt cgtcggaggg
    14581 gtcggggaca gcggccagct cggccagctc cggcgtgatc gcggtaccac acttggaaca
    14641 gaggaagacg gtcatcccct cgttgtagtc ctcagacctg ctgcttcgca ccttcgtttg
    14701 gctgctcgga gtcgatacgc gcgacgacgc tgcggaaatc gggcatgccg agatggacgg
    14761 tgccgtgtcg gacctcgaag tcgcgcatgg cggcgagttc ttgttcggcg gcggcaaggc
    14821 tggcctcgat cgcggcgact tcgcccagcc aaccctgttc ctgggcctca cggagtcgat
    14881 cgtatggcgc agccacggcc atcgaggtcg cgccactcac acctgagccc actccacggg
    14941 tgtccacgtg cgagcgcacc gagcacccca tggccgtcat tgcttatcgg agctcaggca
    15001 gtggtccgga gttcttcggg tagcagccct cttcaagccg gaggaggtac ttccggaggt
    15061 ccgcgccgag cccttcagtg atgtaggcgg caaaatccct cagcccctcc gcggcttccc
    15121 gctcgtcaga cctgtcgctg gacgaccatg tgggcaggag ggactccagg tactcggtga
    15181 cccgcccacg gtcgcgccac cagtcccgaa cagcctcggg tgtccatcgg ctgtcgccgt
    15241 cgcaggcata gccgcggtac ggatcttcct gggcggctgt caccaggttc aggacctcgg
    15301 ccgtggtcgc cggctggcga tacacatatt caccgaagta ctcgccgccg tagagcacat
    15361 gacgcggtgc gtgcagccgg cccgtccaac agttatcggc gatgtcggta tagaaggggc
    15421 caggaacgtt caaccagagc cggtcctccc aacgcccgcc gaaggacgtc tcgggctcgc
    15481 cttctggaag cgccgctatc ggttcccagc acaactcttc ataggtcatc cgcgaagctt
    15541 aggatccgat gggaaggatc tctcaacgtc tgcgctgctt cgtctagcgg ccggtggtcg
    15601 ccagatcggt gtgccgcagg atcgcccgga cctgcgcgag cgtgaggtgt gggtcgttgg
    15661 ccatgcggct cgcggccgtg tgccttgtgt ccgcagaggc cgtgtacggg tgatcccgtg
    15721 tggcgattga gcaggcgcgt cgctgtggac cactttcgtg acgtaggcag cgggaggtgt
    15781 tgcatgtcgc gaccgtcgat gtgatgcgga tcactctctg ggtgcatcgg gtcgggcatg
    15841 cggaatcatg atcggaatgg actctcgttt ccttggcatc cctgagctgg tcgaagcccc
    15901 gtccgtggcg gtcgtagtcg acgtcatgcg tgccttcacc gtggctgcct gggcctttgc
    15961 ccagggggcg gaaaagatcg ttcttgctga gtcgctggac gaagctctgg cactcaaggc
    16021 tcgccaccag gattgggtgg cgctcaaaga cggtccgccc gcgcccgggt tcgacaccgt
    16081 caactcgccg ggactgctgc ggtctattga ccttggcgga cggaccgttg tgcagaagac
    16141 cacggcagga acggtcggcg cccttgcggt caaggaggcg tccctggtgc tgtgcgccag
    16201 cttcgtggtg gcggaggcaa cggctcggct cttgcggacg cgcaacagtg acagtgtcac
    16261 gttcgtggtc actggcgaag ctgggcaggc cgatgaagat ctggcgtgcg ctcaatacat
    16321 cgctcggagg gccaccgaga ccgggacgga tgctgctgag ttcctccgcc gcgctgccga
    16381 gtcgcgcgcc gccgccgagc tggcggaggg tgtgcgtcaa ggagtccatc ctgatgacgt
    16441 cgcgctctgt cttgagctcg accggttccc ctttgccatg gtggcgacct cggaagactc
    16501 gctcatggtc ctccgtccgt gcgccgtgcc ttcgctgacc gacgaggctt cgatctgatc
    16561 gctggtgagg tccaactctc cccatgcgag agccagtacc gagtcgggta tgcagcatca
    16621 gccgcatgtc ccgatgacgg tggttcgggg tggcggcagg tggctgaccc gagtggtgcc
    16681 agcggcggct tcgcggagtc gaatgatctc ttcgtgctgg gcggcgaggc gggccagggc
    16741 ctgggtgcgg aagtccgtga gctcgtcgat cctccactcc gatcgggcga gccgttcttt
    16801 gagctggacg agatccgctc gcccgccgag ctcaccctgc ccgcggtgga cctctccgag
    16861 gaggagatcg agagggccct caccctgctg gactcgatga ccgtcgagca cctggccgac
    16921 ctcggcgacg ccctcaccga ccactacacg gaggcgctgc acgaggtgat cgaggccaag
    16981 gccgaggacc gcgcgccgcg gccggtcgag ggcgaggcgg cgccggccgg gcaggtcgtc
    17041 gatctgatgg ccgcgctgga ggcgtcggtg gcggaggccc gcgaacgccg gggcgaggcc
    17101 ccggcagccg ggggcggcgg cgaggaggcg acggtgcacg agctgccgag gaagaaggcg
    17161 cccgcgaaga aggccggggc caagaagacc acggcgaata aggctctggc gaagaaggcg
    17221 gcgtcccggc ggcggaagcc ggcgtagctc agcccaggag cccgagctcg gtgtccagcc
    17281 ggcagaacgg gcacgccgag acgttgtcgg cggtgagagg cctcgtgcct cgtcgtgggt
    17341 gaggggccgg gtgtgcccgc cggacatgcg gcagtctccg agatggacgc ggtcggggac
    17401 cgggcggccg cgctcgcgca ggtagcccag gacccaggtc ggcccctcgg gcaagggccg
    17461 ctgcgggcgc atggccgcgt ccctggcctc gatctctgcg atccgggccc gcgcggcggc
    17521 gccgagaagg tcggccagcc gcacgatcgt ccgcagctga gggaggtcgt ccggaagcgg
    17581 gatctgtgcg gtcacatcga cgcgagggcc ggcggccggt gggtgaaggc catcgcgggc
    17641 gcggacgcct ggcactcctg gcagagcggg cagccgccgg gaccgtagcg gtggcacttg
    17701 gcgtggcagc gggcgcagag cccgacctgg tccgacgggg tcatctccgg ccgcatgttc
    17761 ttcggggagg gccggtaggg ggcggcaggg ctggtcatgg cggtgacttc ctcaagcagg
    17821 ggcggcgacc gcaccagggt gagtcggttg tgccggagcg tgacaactgt cacctgggat
    17881 gccgctccgc ctgggcgtag ccgtaggacg gagcacgacg gttgtcactg tctgctcagg
    17941 attcttgtca cctgtgggat gtgtgatccg ccagctactg ttcgagcagc ttcccggata
    18001 caccggagtg gacgtggccg accgcggcgc cgacccggcc ggtgaggcgc tgctgacggt
    18061 ggacgagatg gagcacctga tcgcgacctg ggtggtggcc gtctggcagc gccgcgcgct
    18121 gggcgagttc gcgcctggct gggaccccga cggcgacagt gaacccgccg accactactt
    18181 cgtgatggac atcgaaggtc ttgctgagac caaccgctgg gcgctcgtac gcaaagttct
    18241 caacgacaac gaccagttca ccgagggctg gaccgtgccc atccggcacg acgaccgcac
    18301 aacgacgatg tcggccgacg acgcccgccg gctcatgaac gacggccagc gcagccggac
    18361 agctcctccc tggcctgcgc tcgcaccact gccgccctcc gacccatccc aggaccgcca
    18421 gcatctagag gcccatctca ggtgggacga gctgcccatc atgttctggc agagcacgcc
    18481 gcagaacgcc cccgagctca tcaccggtct gcacagccag gaggggatcc ggggagccct
    18541 gctcgatcaa aacgcgttgc ggccccaggc cggcttcaac ttctcgtccg agtacaaacg
    18601 gccggagccc taccggggcg gactccccct ggccgacagt cgccgggcca tcgccggcgg
    18661 cgcggacggc acagtgaccg ccgccgttgt cgcgaccagc gaaatgctcg gctggggcat
    18721 ggagcagcag ttcggcgaga ccggcaggat caacgtcgtc accctgtccg agatgacgct
    18781 ggagtacttc cgcctcgtcg acaaaaggat caggcccgcc atctccgggt cgtggcagca
    18841 caggatcgtc gccacccgct tcgcgcagga gcccgtccgc actctggcac ccggagcaaa
    18901 tcccgagttc ccggtcttcg gggccgcaag ccaggtgagc gccgacacgt ggaaccagtc
    18961 gtggaccgcg tacggagatc ccgagcagga cgcatactaa ctgatcgttt cagaatgagg
    19021 ttcggaggcg gcggaggcat atgaggctgc aggccagttc gagcaggccc tggtggagat
    19081 cggcgcgtcg ttcgtagcgg gtgcgggccg tggcgcacgc ctcc
//
