LOCUS       NZ_JABBGE010000010     12868 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. R302 contig10, whole genome shotgun sequence.
ACCESSION   NZ_JABBGE010000010
VERSION     NZ_JABBGE010000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. R302
  ORGANISM  Streptomyces sp. R302
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 269498)
  AUTHORS   Dahal,R.H.
  TITLE     Streptomyces sp. R302 sp. nov., isolated from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 269498)
  AUTHORS   Dahal,R.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) Life Science, Kyonggi University, Kyonggi
            University, Suwon, Gyeonggi-Do 16227, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2020
            Assembly Method                   :: SPAdes v. APR-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012927245.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 03:52:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,357
            CDSs (total)                      :: 7,271
            Genes (coding)                    :: 7,075
            CDSs (with protein)               :: 7,075
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 84 of 196
            Pseudo Genes (incomplete)         :: 164 of 196
            Pseudo Genes (internal stop)      :: 20 of 196
            Pseudo Genes (multiple problems)  :: 67 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 148245
            Orig. end                         :: 161113
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBGE010000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12868
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="2"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12868
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12868
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7868](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7868
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(185..655)
                     /locus_tag="HHL19_RS29145"
                     /old_locus_tag="HHL19_29155"
     CDS             complement(185..655)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742769.1"
                     /locus_tag="HHL19_RS29145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29155"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_169093354.1"
                     /transl_table=11
                     /translation="MSVADDAAVRVRPVRKDDFDQWRALYRGYAAFYRVEQSEEAAALV
                     WSWLHDPGHEVEGLVAEGSDGRLVGLAHFRAFARPLSASVGGWLDDLFVDPASRGTGAA
                     DALLAALRGIGAERGWSVVRWITADDNHRARSKYDQVATRTMWITYDMAPEA"
     gene            847..2307
                     /locus_tag="HHL19_RS29150"
                     /old_locus_tag="HHL19_29160"
     CDS             847..2307
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980906.1"
                     /locus_tag="HHL19_RS29150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29160"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_169093355.1"
                     /transl_table=11
                     /translation="MATDRYGNTLYACTPEGAAHLDRAVEALLFFRPEVAPAVEDALAA
                     SPGSPDAQAFAAYLGVLGTEHTGAAEARTRFERFLADCDTSALPARERLHLAAAGACLA
                     GNLHGAGDLLEELSLAYPRDVLALFAGHQLDFLTGDAVRLRDRIGGALSAWGRADEHRG
                     PLLGMYAFGLEESGHYRRAEETGLAAVERHPRDVWAVHAVTHVYEMQGRVAEGVAFLDG
                     RADDWARGNYLTVHNWWHYALYALEAGAEETALRVYDAAVHHEESAGLAMELLDAAALL
                     WRLRLAGREEPERWARLADAWAARADPPFYAFNDAHAVMAYVGAGRIAEAEALVADRRR
                     WLAEGEGEGDRRTLSNHAMTAEVGLPVCEALVAQGRGDHAAVVELLWPLRRRIQVFGGS
                     HAQRDAVQRTLLESALAAGEHDRARLLLSERDGLRPDSPYNWLGRARLADAIGDAALAA
                     VARGRAEGAAKGLRPTAPGLGSVPNSPR"
     misc_feature    2412..2428
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    2416..2426
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    2420..2433
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.09"
                     /tool="antismash"
     misc_feature    2514..2528
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            2540..4930
                     /locus_tag="HHL19_RS29155"
                     /old_locus_tag="HHL19_29165"
     CDS             2540..4930
                     /EC_number="3.4.24.3"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267147.1"
                     /locus_tag="HHL19_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29165"
                     /product="collagenase"
                     /protein_id="WP_169093356.1"
                     /transl_table=11
                     /translation="MSQHRVVRSSLLATAIAVTLVASAGQAATQAAEAPAPRAAAATSG
                     VPGAFAPTAAAEPNPFDEVERFAKARTATPAPAPAPGGTGDTRARVPGQAKKDAKATAK
                     QGKAQSAPAATLAAGVPCTLDGITGLSPAAFADFLADPAVTADGCLTGLIWTWDARLAP
                     VMSDAHVQAVANRISGLAAAHDGRNSSHLEEMFTYLHAVAYHDFSRDEIDITDAPTVDA
                     VRRAIAAFGSAARTFDVTASNARTLREALYIGSAPGLRQHQLGLITKVLATMDPAHPAT
                     NQDPTWAGAALSALSVNYLGIYSGNHDTAFHAAVAADPAYRAVFKAFAGYTHLKGTANA
                     WVARDAISEYGRFGEVAGLRNGIVADLGAMIGPVESAWGPGSQPWAKIVSWLNFYDACA
                     PYGVCKADIEARIFPYTYTYDTGTGAALKVRTGLDRATVDQLYYASKQVKAQFHRVVGS
                     DQPLAGDPNTTLNIVLYGSRADYENYHPILTGYDTNNGGIYIENGATFYTYQRRVPQDS
                     SLTLEELFRHEYTHYLNGRFAVPGFFGQGPWYQGDRTTFMDEGTAEFFDGATRDDGIAV
                     RKSLVRSIINDTAGGGPRMNLRQILHATYDGDGFRFYSYAGTFFEFLWTERPSLIREMY
                     TRLRADDVAGYDAWRERLSSDAGLQQAYDRFLDAQIAKVDELFVPDTSYTPNGQLTYST
                     VSGVKTAFANATYNTPDCVEKGEPGKRRFECTGRITANLANPGSDDQNFKDMSETVDYF
                     ILDRSGAALNNLADMNCSFGPIEIWSNRVAGTSSFRCEGPLRS"
     gene            5001..6176
                     /locus_tag="HHL19_RS29160"
                     /old_locus_tag="HHL19_29170"
     CDS             5001..6176
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038321.1"
                     /locus_tag="HHL19_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29170"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_169093357.1"
                     /sec_met_domain="DAO (E-value: 2.3e-68, bitscore: 225.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNRHSPDVVIIGAGVVGAACAYYAARSGLTVAVVDRGPVAGGTT
                     GAGEGNLLVSDKEAGPELDLALLSTRLWRELSATLPPETEYEPKGGLVVAPDESALRAL
                     RAFAEGQRKAGVTATELPADRLAELEPHLAPGLAGGFHYPQDAQVQPAQAAARLLAASG
                     AALHLGEEVTAILRGPAGAVRGVRTPRRELLAPAVVNAAGTWGGEAARLAGVHLPVLPR
                     RGFVLVTEPLPRIVRHKVYAADYIADVASGSAALQSSAVVEGTPGGPVLIGATRERVGF
                     DRSLSTEALRRLAAQAAALFPVLAGVQVLRAYHGFRPYLPDHLPAIGPDPRVPGLHHAC
                     GHEGAGIGLAPATGALVAAALTGAEPPLDPAPFRPERDFGPADAPTQEQQS"
     gene            6173..6490
                     /locus_tag="HHL19_RS29165"
                     /old_locus_tag="HHL19_29175"
     CDS             6173..6490
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005309276.1"
                     /locus_tag="HHL19_RS29165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29175"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_169093358.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.7e-27, bitscore: 89.3,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRTPRALVGGAPQETFTFRFDGRDIPAAAGQTVAAALWGAGVL
                     AWRTTRHGGEPRGAFCGIGQCFDCLVTVDGTPNRRACLVPARPGGLVTSQEGTGHDDLA
                     V"
     gene            6471..7868
                     /locus_tag="HHL19_RS29170"
                     /old_locus_tag="HHL19_29180"
     CDS             6471..7868
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237884.1"
                     /locus_tag="HHL19_RS29170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29180"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_169093359.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-26, bitscore:
                     87.6, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1e-13, bitscore: 45.4,
                     seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSPSDSGTAPVDLAIVGAGPAGLAAAVTAAALGRTVTLLDAGA
                     RPGGQYYRHPDPALGATRPQALHHDWAAFAGREAELRAHERAGRVRYLANHQVWSVTGS
                     GTDWRVHSRTDDEAGEPVRARAVLLATGAYERQLPFPGWTLPGVVGAGGAQAMLKSGLV
                     LPGRRVVVAGSGPLLLAVAASLAAAGARVPAVVEAAGYGPYARHTGTLLRNPAKLAEGA
                     LYGAALLRHQVRPLLRHAVVEAHGTDRVEAVTVARLDRDWRPVPGTGRRIPCDALAVGH
                     GLVPELSLATALGCTTRTAADGTAALVLTPGLRTSVPGVWAAGETGGVGGAQLALTEGE
                     IAAHSIAGQAVPTPLARRRERLRAFADAMGAAHRPGAGWTGWLREETAVCRCEEVPAGR
                     VREAVEELGATDARTVKLLTRAGMGWCQGRMCGPAVAALAGGEPAADRRPLACPVRLGE
                     LAELPAD"
     misc_feature    7916..7926
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            7950..8849
                     /locus_tag="HHL19_RS29175"
                     /old_locus_tag="HHL19_29185"
     CDS             7950..8849
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644994.1"
                     /locus_tag="HHL19_RS29175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29185"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_169093360.1"
                     /transl_table=11
                     /translation="MTDTRTRPWHGIMVATTLPLREDLSVDLDAYAAHVRWLIDNGCDG
                     VVPNGSLGEYQTLTDAERAAVVRTAVEAAGDGSRVMPGVAAYGSAESRRWAEQAAEAGA
                     GSVLLLPPNAYRADEDAVRAHYAEVARVGLPIVAYNNPIDTKVDLTPALLARLHADGNI
                     VAVKEFSGDVRRAYEIAELAPGLDLLIGADDVLLELALAGAVGWIAGYPNALPESAATL
                     YRAAVAGDLATALPLYKALHPLYRWDSKTEFVQAIKLSMDLAGRPGGPTRAPRLPLTGA
                     VETAVRAATEKVLAEGLR"
     gene            8870..9874
                     /locus_tag="HHL19_RS29180"
                     /old_locus_tag="HHL19_29190"
     CDS             8870..9874
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="HHL19_RS29180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29190"
                     /product="proline racemase family protein"
                     /protein_id="WP_169093361.1"
                     /transl_table=11
                     /translation="MRTRHVYHAVDSHTEGMPTRVITGGVGVIPGATMAEKRLHFMAHR
                     DDLRTLLMYEPRGHAAMSGAILQPATRPDADYGVLFVEVSGLLPMCGHGTIGVATVLVE
                     TGMVPVTEPVTTVRLDTPAGLVSAAVRVEDGAARSVTLTNVPAFSVGLDLKTEVPGYGT
                     VTYDLAYGGNFYAFVELDALGLPFDRARKQDLLTAGLAIMDAINAGDDRPVHPEDPAVA
                     GVKHVYLAAPGSDARRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGQLALDTDFVNE
                     SFIGTEFTGRLVAETTVGGRPAVVPTVTGRAWITGTAQYFLDPTDPFPAGFLL"
     gene            9862..10917
                     /locus_tag="HHL19_RS29185"
                     /old_locus_tag="HHL19_29195"
     CDS             9862..10917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267153.1"
                     /locus_tag="HHL19_RS29185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29195"
                     /product="proline racemase family protein"
                     /protein_id="WP_346768550.1"
                     /transl_table=11
                     /translation="MPAVTALPADGVRVTDYHTAGEPFRIVADGLPPAPGDTVAERCAT
                     AIGAGGSGTAPRPGPLDALRRFLVQEPRGHAGMYGGFVVPPDDDGAHLGVLFWHKDGFS
                     TACGHGTIALAAWAVDTGRVPAGDGDRDVPVRIDVPSGRVTATVHRSGGRTTGVTFRNV
                     PARVTARRVPVATGLGIVEADLAHAGACYASVSARELGLTVDKASLPALTRVGREIRTT
                     LAGHPATWHPDGPLLSGVYGVILYEDLPDTPEGPRQRNVTVFADGQIDRSPCGSGTSTR
                     LALLADQGSLKEGQVLTHESVAGTVFTGRVLPGGDPDGGLVTEVTGTAHRTGEAHFTLD
                     PDDTLGAGFLL"
     gene            10914..11852
                     /locus_tag="HHL19_RS29190"
                     /old_locus_tag="HHL19_29200"
     CDS             10914..11852
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537613.1"
                     /locus_tag="HHL19_RS29190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29200"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_169093362.1"
                     /transl_table=11
                     /translation="MTALPYLDGGAVTRALAPAAAVEALAGVLRDGLDPETCPPRSAVP
                     VPAGELLLMPAAAGDWAGVKIAGVAPGNAALGLPRITGSYLLLDGTTLRPRALLDGAAL
                     TALRTPAVSALAVRHLTPGERPLRVVMFGSGPQAYGHVDALLAVRKLASVTVVARDPGR
                     AEGLAAYARGIGVPEARRGTAAEVAEADLVVCCTTARTPLFDGRRVAPGAVVVAVGSHE
                     PDARETDTALVRRSEVWVEARTAALREAGDLLIPEAEGAIGPGHITGTLADLVRGPALP
                     APGPAPRLFKSVGMAWQDLAVAVAVHRAATG"
     misc_feature    complement(11858..11868)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            11902..12618
                     /locus_tag="HHL19_RS29195"
                     /old_locus_tag="HHL19_29205"
     CDS             11902..12618
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036954.1"
                     /locus_tag="HHL19_RS29195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_29205"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_169093363.1"
                     /transl_table=11
                     /translation="MGDLKQHSLIKAQERLRDQVGHALRAALTAGELKPGTVYSAPGLA
                     AELGVSATPVREAMLDLAREGLVEPVRNKGFRITEVSERELDQCTELRMLIEVPTVGRV
                     TETATAEQLEALRPLAEEIVVNAREHNLIGYLEADRQFHLTLLGLSGNDRLVETVGDLR
                     KRSRLYGLTGLDEAGKLVSSAEEHVELLDLMIARDRAGAEACMMRHLGHVRSLWAEARD
                     EPVEPAAGALRSVRKR"
ORIGIN
        1 cgacaagacc ggcggcggcg attacggcgg caacaacgac gtcgcggtca cctggccgcc
       61 ggacggcggc ccgatcctcc tcgccgtcct caccacccgg ttcgaccggg cggcgaaggg
      121 cgtcgacgaa ctcgtggccg ccgccgcggc gatcgtcgcc gaggaactcc gctagggcct
      181 gttctcaggc ctccggggcc atgtcgtacg tgatccacat cgtgcgcgtg gccacctggt
      241 cgtacttgga gcgggcgcgg tggttgtcgt cggccgtgat ccagcggacg acgctccagc
      301 cgcgctccgc gccgattccg cgcagcgcgg cgagcagggc gtcggcggcg ccggtgccgc
      361 ggctcgccgg gtccacgaac aggtcgtcga gccagccgcc caccgacgcg gacagcggcc
      421 gggcgaaggc ccggaagtgc gcgagtccca caaggcgtcc gtcggagccc tccgccacca
      481 gcccctccac ctcgtggccg gggtcgtgga gccacgacca gacgagcgcc gcggcctcct
      541 cgctctgctc gacccggtag aacgcggcgt agccccggta cagggcgcgc cactggtcga
      601 agtcgtcctt ccggaccgga cggacccgga cggcggcgtc gtcggcgacc gacatgaacg
      661 ttcactctcc tcgtgctgcg tgctgcgtgc tgcgtgctgc gtgctgtcgt gcggggaaca
      721 gtggatcatg ccgccgggcg gagtggcacg ggagccggtg gggcacgctc ccggcagcat
      781 ccggcagcat ccggcagcat ccggcagcat ccggcagcat ccgaggaacc gaggtgagga
      841 tccgcgttgg cgaccgaccg ctacggcaac accctgtacg cctgcacccc cgagggggcc
      901 gcccatctgg accgggccgt ggaggccctg ctcttcttcc ggcccgaggt ggccccggcc
      961 gtcgaggacg ccctcgcggc gagccccggc tcgcccgacg cccaggcctt cgccgcctat
     1021 ctgggggtgc tcggcaccga gcacaccggc gccgcggagg cccggacccg cttcgagcgc
     1081 ttcctcgccg actgcgacac ctccgcgctg cccgcgcgcg agcggctgca cctggccgcc
     1141 gccggcgcct gtctcgccgg gaacctgcac ggggcgggcg acctcctgga ggagctgtcc
     1201 ctcgcgtacc cgagagacgt cctcgcgctc ttcgccgggc accagctgga cttcctcacc
     1261 ggggacgccg tccggctgcg ggaccggatc ggcggcgccc tgtcggcgtg ggggagggcc
     1321 gacgagcacc gggggccgct gctcggcatg tacgccttcg gtctggagga gtcgggccac
     1381 taccggcgcg cggaggagac gggcctcgcg gcggtggagc ggcatccgag ggacgtgtgg
     1441 gcggtgcacg cggtgaccca tgtgtacgag atgcagggca gggtcgccga gggcgtcgcc
     1501 ttcctcgacg gccgcgcgga cgactgggcg cgcggcaact acctgacggt gcacaactgg
     1561 tggcactacg cgctgtacgc cctggaggcg ggcgcggagg agaccgcgct gcgcgtctac
     1621 gacgcggccg tccaccacga ggagtcggcc gggctcgcca tggaactcct ggacgccgcc
     1681 gcgctgttgt ggcgtctgcg gctcgcgggc cgggaggagc cggagcgctg ggcgcggctc
     1741 gccgacgcct gggccgcgcg ggccgatccg ccgttctacg ccttcaacga cgcccacgcc
     1801 gtgatggcgt acgtgggggc cggccggatc gcggaggcgg aggcgctggt ggccgaccgc
     1861 cgccggtggc tggccgaggg agagggcgag ggggaccggc gtaccctctc caaccacgcc
     1921 atgacggccg aggtcggact cccggtctgc gaggcgctgg tggcgcaggg gcgcggtgac
     1981 cacgccgccg tggtggagct gctgtggccg ctgcggcgca ggatccaggt cttcggcggc
     2041 agccacgccc agcgggacgc cgtccagcgg acgctcctcg aatcggcgct cgccgccggg
     2101 gagcacgacc gggcccggct gctgctgagc gagcgggacg ggctgcgccc ggacagcccg
     2161 tacaactggc tggggcgggc ccggctggcc gacgcgatcg gtgacgcggc gctcgcggcg
     2221 gtggcgcgcg ggcgggcgga gggtgcggcg aaggggctga ggccgacggc gcccgggctc
     2281 ggatccgtac cgaactcacc gcgctgacct gcgggttcgg ctccggatca ggcggccggg
     2341 cgtccgcctc cccccgttcc ctcacggagg cggacgcccg gctctcacaa ctgacccgcg
     2401 cacagggctt gtcagtgcaa tttcacatta ctatgttaca gctcgtgcgg cggacggcct
     2461 tctctccgtc aactcgcgtt caggtgccgc tgatcggccg cgcaaccccc ctcatcccca
     2521 ccctcgatca ggagacctcg tgtcccagca cagagtcgtg cgctcctccc tcctcgccac
     2581 cgcgatcgcc gtgaccctcg tggcctccgc cggacaggcc gcgacccagg ccgccgaggc
     2641 gcccgccccg cgcgccgccg ccgcgacgtc cggcgtgccc ggcgccttcg cgcccaccgc
     2701 cgccgccgag ccgaacccct tcgacgaggt ggaacgattc gccaaggccc gtacggccac
     2761 gcccgccccg gcccccgccc ccggcggcac cggcgacacc agggcccgcg tccccggcca
     2821 ggcgaagaag gacgccaagg ccaccgccaa gcagggcaag gcccagtctg cgcccgccgc
     2881 caccctcgcc gccggcgtgc cctgcaccct cgacggcatc accggcctct ccccggcggc
     2941 cttcgccgac ttcctcgccg accccgccgt caccgccgac ggctgtctga ccggcctcat
     3001 ctggacctgg gacgcccgcc tcgccccggt catgtccgac gcccacgtcc aggccgtcgc
     3061 gaaccggata tccggcctgg ccgccgccca cgacggccgc aactcctccc acctggagga
     3121 gatgttcacc tatctccacg ccgtcgcgta ccacgacttc tcgcgcgacg agatcgacat
     3181 caccgacgcc ccgaccgtcg acgccgtccg ccgcgccatc gccgccttcg gctccgccgc
     3241 ccggaccttc gacgtcaccg cgtccaacgc ccgcaccctc cgcgaggccc tctacatcgg
     3301 cagcgccccc ggcctgcgcc agcaccagct cggactcatc accaaggtgc tcgccaccat
     3361 ggacccggcg caccccgcca cgaaccagga cccgacctgg gcgggcgccg cgctgtcggc
     3421 gctctccgtc aactacctgg gcatctactc cggcaaccac gacacggcct tccacgccgc
     3481 cgtcgccgcc gacccggcct accgcgccgt cttcaaggcc ttcgccggct acacccacct
     3541 caagggcacc gccaacgcgt gggtcgcccg cgacgcgatc agcgagtacg gccgcttcgg
     3601 cgaggtcgcc ggcctgcgga acgggatcgt cgccgacctc ggcgcgatga tcggccccgt
     3661 cgagtccgcc tggggccccg gcagccagcc ctgggccaag atcgtgtcct ggctgaactt
     3721 ctacgacgcc tgcgccccgt acggcgtctg caaggccgac atcgaggccc ggatcttccc
     3781 ctacacgtac acctacgaca ccgggaccgg cgccgccctc aaggtccgca ccggcctcga
     3841 ccgggccacc gtcgaccagt tgtactacgc gagcaagcag gtcaaggcgc agttccaccg
     3901 ggtggtcggc agcgaccagc cgctggccgg cgaccccaac accaccctga acatcgtgtt
     3961 gtacggctcc cgggcggact acgagaacta ccacccgatc ctgaccgggt acgacacgaa
     4021 caacggcggc atctacatcg agaacggcgc caccttctac acgtaccagc gccgcgtccc
     4081 gcaggactcc tccctcaccc tggaggagct gttccgccac gagtacaccc actacctcaa
     4141 cgggcgcttc gccgtccccg gcttcttcgg ccagggcccc tggtaccagg gcgaccggac
     4201 caccttcatg gacgagggca ccgccgagtt cttcgacggc gcgacccgcg acgacggcat
     4261 cgccgtccgc aagtccctgg tccgcagcat catcaacgac accgcgggcg gcggcccccg
     4321 catgaacctc cggcagatcc tgcacgccac ctacgacggc gacggcttcc gcttctacag
     4381 ctacgcgggc accttcttcg agttcctgtg gaccgagcgc ccctcgctga tccgcgagat
     4441 gtacacccgc ctgcgcgccg acgacgtcgc cggctacgac gcctggcgcg agcggctcag
     4501 ctccgacgcc ggactccagc aggcgtacga ccgcttcctc gacgcgcaga tcgccaaggt
     4561 cgacgagctg ttcgtgcccg acacctccta cacgcccaac gggcagctca cgtactcgac
     4621 cgtctccggg gtgaagaccg ccttcgccaa cgccacgtac aacacgccgg actgcgtcga
     4681 gaagggcgag cccggcaagc gccgcttcga gtgcaccggc cggatcaccg cgaacctcgc
     4741 gaacccgggc agcgacgacc agaacttcaa ggacatgtcc gagacggtcg actacttcat
     4801 cctcgaccgc tcgggcgcgg cgctgaacaa cctggccgac atgaactgca gcttcgggcc
     4861 gatcgagatc tggtccaaca gggtcgccgg cacgtcgagc ttccgctgcg agggcccgct
     4921 ccgcagctga ccccacgtcc gtcccgccca ggggccgccg gcccctgggc aacgcctgaa
     4981 gaatgtgaca tattactgcc gtgcccaaca gacactcccc ggacgtcgtg atcatcggcg
     5041 ccggcgtcgt cggagccgcc tgcgcgtact acgcggcgcg ctccggactc accgtcgccg
     5101 tggtcgaccg cggtcccgtc gcgggcggca ccaccggcgc cggggaaggc aatctgctcg
     5161 tctccgacaa ggaggcgggc cccgagctcg acctcgcgct gctgtccacg agactctggc
     5221 gcgaactctc cgcgacactc ccgccggaga ccgagtacga gcccaagggc gggctcgtcg
     5281 tggcgcccga cgagtccgcc ctccgggccc tccgcgcctt cgcggagggc cagcggaagg
     5341 ccggcgtcac cgccaccgaa ctccccgccg accggctcgc cgagctcgaa ccccacctcg
     5401 cccccggcct cgccggaggc ttccactacc cccaggacgc ccaggtgcag cccgcccagg
     5461 ccgccgcccg gctgctcgcc gcctccggcg ccgcgctcca cctcggcgag gaggtcaccg
     5521 cgatcctccg cggcccggcc ggcgccgtcc ggggcgtgcg caccccgcgc cgcgaactcc
     5581 tcgcccccgc cgtggtcaac gccgccggca cctggggcgg cgaggccgcc cggctcgccg
     5641 gcgtccacct ccccgtcctg ccccgccgcg gcttcgtcct cgtcaccgaa cccctcccga
     5701 ggatcgtccg ccacaaggtc tacgccgccg actacatcgc cgacgtggcc agcggctcgg
     5761 ccgccctcca gtcctccgcc gtcgtcgagg gcacccccgg cggccccgtc ctcatcggcg
     5821 ccacccgcga acgcgtcggc ttcgaccgct cgctctccac cgaggccctg cgccggctcg
     5881 ccgcccaggc cgccgcgctc ttcccggtcc tcgccggcgt ccaggtgctc cgcgcctacc
     5941 acggcttccg cccctacctc cccgaccacc tcccggcgat cggccccgac ccgcgcgtcc
     6001 ccggcctcca ccacgcctgc ggccacgaag gggccggcat cggcctcgcc cccgccaccg
     6061 gcgccctcgt cgccgccgcc ctcaccggcg ccgaaccccc gctcgacccg gcgccgttcc
     6121 gccccgagcg cgacttcggc cccgccgacg ccccgaccca ggagcagcag agttgagccg
     6181 ccgcaccccg cgcgccctcg tcggtggcgc gccgcaggag accttcacct tccgcttcga
     6241 cggccgggac atcccggccg ccgccgggca gaccgtcgcc gccgccctgt ggggcgcggg
     6301 cgtcctcgcc tggcgcacca cccggcacgg cggcgaaccc cggggcgcct tctgcgggat
     6361 cggtcagtgc ttcgactgcc tcgtcaccgt cgacggcacc cccaaccgcc gcgcctgcct
     6421 cgtccccgcc cgccccggcg gcctcgtcac cagccaggag ggaaccggcc atgacgacct
     6481 cgccgtctga ctccgggacc gcgcccgtgg acctcgcgat cgtcggcgcg ggacccgccg
     6541 gtctcgccgc cgccgtcacc gccgccgccc tcggccgcac cgtcaccctg ctcgacgcgg
     6601 gcgcccgccc cggcggccag tactaccgcc accccgaccc ggccctcggc gccacccgcc
     6661 cccaggccct gcaccacgac tgggccgcct tcgccggccg cgaggccgag ctccgcgcgc
     6721 acgaacgagc gggccgcgta cgatatctgg cgaaccatca ggtgtggagc gtcaccggct
     6781 ccggaaccga ctggagagtc cactcccgca ccgacgacga ggccggggag cccgtccggg
     6841 cccgcgcggt gctgctcgcc accggggcgt acgagcgcca gctgccgttc cccggctgga
     6901 ccctgcccgg cgtcgtcggc gccgggggcg cccaggccat gctcaagagc gggctcgtgc
     6961 tccccggccg ccgcgtggtc gtcgcgggca gcgggccgct gctgctcgcc gtcgccgcct
     7021 ccctcgccgc cgccggcgcc cgtgtccccg ccgtcgtcga ggccgccgga tacggcccgt
     7081 acgcccgcca caccggcacc ctgctgcgca acccggccaa gctcgccgaa ggcgccctct
     7141 acggcgctgc gttgctccgc caccaggtcc gcccgctgct ccggcacgcc gtcgtcgaag
     7201 cgcacggcac cgaccgcgtc gaggcggtga ccgtcgcccg gctcgaccgc gactggcgcc
     7261 ccgtgcccgg caccggccgc cggatcccct gcgacgcgct cgccgtcggc cacggcctgg
     7321 tccccgaact ctccctcgcc accgccctcg gctgcaccac ccgcaccgcc gccgacggca
     7381 ccgccgccct cgtcctcacc cccggcctgc gcacctcggt gcccggcgtc tgggcggcgg
     7441 gcgagaccgg cggcgtcggg ggagcccaac tcgcgctcac cgaaggcgag atcgctgccc
     7501 actcgatcgc cggacaggcc gtcccgacgc cgctcgcccg gcgccgggag cgactgcggg
     7561 ccttcgccga cgccatgggc gccgcccacc ggcccggtgc cggctggacc ggctggctcc
     7621 gcgaggagac cgccgtctgc cgctgcgagg aggtgccggc cgggcgggtc cgcgaggcgg
     7681 tggaggagct gggcgccacc gacgcccgca cggtcaagct gctgacccgc gcggggatgg
     7741 gctggtgcca gggccgcatg tgcggtccgg cggtggccgc gctcgccggc ggcgaacccg
     7801 ccgccgaccg gcgcccgctg gcctgccccg tacggctcgg ggagctcgcc gagctccccg
     7861 ccgactagcc ccttccgtgg tggtcacact cttgtggccg ccgcacaccc cctagtaaaa
     7921 tgtcacacac tacaaaggag tacgtcacca tgaccgacac ccgcacccgc ccctggcacg
     7981 gcatcatggt cgccaccacc ctgccgctgc gcgaggacct ctccgtcgac ctcgacgcct
     8041 acgccgccca cgtccgctgg ctcatcgaca acggctgcga cggcgtcgtc cccaacggct
     8101 cgctgggcga gtaccagacc ctcaccgacg ccgagcgcgc cgcggtcgtc cgcaccgccg
     8161 tcgaggccgc cggcgacggc tcccgcgtca tgcccggcgt cgccgcctac ggctccgccg
     8221 agtcccgccg ctgggccgaa caggccgccg aggccggcgc cggctccgtc ctgctcctgc
     8281 cgcccaacgc ctaccgcgcc gacgaggacg ccgtccgcgc ccactacgcc gaggtcgccc
     8341 gcgtcgggct gccgatcgtc gcctacaaca accccatcga caccaaggtc gacctcaccc
     8401 cggccctcct cgcccgcctc cacgccgacg ggaacatcgt cgccgtcaag gagttcagcg
     8461 gcgacgtccg ccgcgcctac gagatcgccg aactcgcccc cggactcgac ctcctcatcg
     8521 gtgccgacga cgtcctcctg gagctcgccc tcgccggtgc cgtcggctgg atcgccggct
     8581 accccaacgc cctgcccgag tccgccgcca ccctctaccg ggccgccgtc gccggcgacc
     8641 tcgccaccgc gctgccgctc tacaaggcgc tgcaccccct ctaccgctgg gactccaaga
     8701 ccgagttcgt ccaggccatc aagctctcca tggacctcgc cggccgcccc ggcggcccca
     8761 cccgcgcccc gcgcctgccg ctcaccggtg ccgtcgagac cgccgtccgc gccgccaccg
     8821 agaaggtcct ggccgaaggc cttcgctgac cccaggggga agacagccca tgcgcacccg
     8881 acacgtctac cacgcggtgg actcccacac cgagggcatg cccacccggg tgatcaccgg
     8941 cggagtgggg gtgatccccg gcgccaccat ggccgagaag cgcctccact tcatggcgca
     9001 ccgcgacgac ctgcgcaccc tgctcatgta cgagccccgc ggccacgccg ccatgagcgg
     9061 tgcgatcctc cagcccgcga cccgccccga cgccgactac ggagtcctct tcgtcgaggt
     9121 ctccggcctg ctcccgatgt gcggccacgg cactatcggc gtcgccaccg tcctcgtcga
     9181 gaccggcatg gtcccggtca ccgaaccggt caccaccgtc cgcctcgaca ccccggccgg
     9241 actcgtctcc gccgccgtcc gcgtcgagga cggcgccgcc cgctccgtca ccctcaccaa
     9301 cgtccccgcc ttcagcgtcg gactcgacct caagaccgag gtccccgggt acggcaccgt
     9361 cacctacgac ctcgcctacg gcggcaactt ctacgccttc gtggaactcg acgccctcgg
     9421 cctccccttc gaccgcgccc gcaaacagga cctgctcacc gccggactgg cgatcatgga
     9481 cgcgatcaac gcgggcgacg accggcccgt ccaccccgag gacccggccg tcgccggcgt
     9541 caagcacgtc tacctcgccg cccccggctc cgacgcccgc cgctcccggc acgccatggc
     9601 catccacccc ggctggttcg accgctcccc gtgcggtacc ggcaccagcg cccgcatggc
     9661 ccagctgcac gcccgcggac agctcgccct ggacaccgac ttcgtcaacg agtccttcat
     9721 cggcaccgag ttcaccgggc ggctcgtcgc cgagaccacc gtcggcggcc ggcccgccgt
     9781 cgtccccacc gtcaccggac gggcctggat caccggcacc gcccagtact tcctcgaccc
     9841 caccgacccc ttccccgccg gattcctgct gtgaccgcac tccccgcgga cggcgtccgc
     9901 gtcaccgact accacaccgc cggcgaaccc ttccggatcg tcgccgacgg cctgccgccc
     9961 gcccccggcg acaccgtcgc cgagcggtgc gccaccgcca tcggcgccgg cggctccggt
    10021 accgcccccc gccccggccc cctggacgcg ctgcgccggt tcctcgtcca ggagccgcgc
    10081 ggccacgccg gcatgtacgg cggattcgtc gtcccgcccg acgacgacgg cgcccatctc
    10141 ggcgtcctct tctggcacaa ggacggcttc tccaccgcct gcggccacgg caccatcgcc
    10201 ctcgccgcct gggccgtcga caccggccgc gtcccggccg gcgacggcga ccgggacgtg
    10261 cccgtccgca tcgacgtgcc gtccggccgg gtcaccgcca ccgtccaccg gtccggcggc
    10321 cgcaccaccg gcgtcacctt ccggaacgtg cccgcccggg tcaccgcccg cagggtcccc
    10381 gtcgccaccg gcctcggcat cgtcgaggcc gacctcgccc acgccggcgc ctgctacgcc
    10441 tccgtctccg cccgcgagct cggcctcacc gtggacaagg cgtccctgcc cgcactcacc
    10501 cgggtcggac gggagatccg caccacgctc gccggccacc ccgccacctg gcaccccgac
    10561 gggccgctgc tctccggcgt ctacggcgtc atcctgtacg aggacctgcc cgacaccccg
    10621 gaaggcccgc gccagcggaa cgtcaccgtc ttcgccgacg gccagatcga ccgctccccg
    10681 tgcggctccg gcacctccac ccggctcgcc ctcctcgccg accagggcag cctcaaggaa
    10741 ggccaggtcc tcacccacga gtccgtcgcc ggcacggtct tcaccggccg cgtgctgccc
    10801 ggcggcgacc ccgacggcgg actcgtcacc gaggtcaccg gcaccgccca ccgcaccggc
    10861 gaggcgcact tcacgctcga cccggacgac accctcggcg cggggttcct cctgtgaccg
    10921 cgctcccgta cctcgacggc ggcgccgtca cccgggcgct cgccccggcc gccgccgtcg
    10981 aggccctggc cggggtcctg cgggacgggc tcgaccccga gacctgcccg ccccgctccg
    11041 ccgtccccgt cccggcgggc gagctgctgc tcatgccggc cgcggccggc gactgggccg
    11101 gggtgaagat cgccggggtg gcgcccggca acgccgccct cggactgccc cggatcaccg
    11161 ggagctacct cctcctcgac gggaccaccc tccggccccg cgcgctgctc gacggcgccg
    11221 ccctcaccgc gctgcgcacc ccggccgtct ccgccctggc ggtccgtcac ctcacaccgg
    11281 gcgagcggcc gttgcgggtg gtgatgttcg gctcgggacc gcaggcgtac gggcacgttg
    11341 acgcgctcct cgcggtacgg aagctcgcct ccgtcaccgt ggtcgcgcgc gacccggggc
    11401 gggccgaggg actcgcggcg tacgcgcggg ggatcggcgt ccccgaggct cgccgcggca
    11461 ccgccgccga ggtcgcggag gcggacctgg tggtctgctg caccaccgcc cggaccccgc
    11521 tcttcgacgg gcggcgggtg gcgcccgggg cggtggtcgt cgccgtcggc tcgcacgagc
    11581 cggacgcccg cgagaccgac accgccctgg tccgccgctc cgaggtctgg gtggaggcgc
    11641 ggacggcggc cctgcgggag gccggcgacc tgctgatccc cgaggcggag ggggcgatcg
    11701 gacccggcca catcaccggc accctcgccg acctcgtccg gggcccggcg ctgcccgccc
    11761 ccgggccggc cccccgcctc ttcaagagcg tgggcatggc ctggcaggat ctcgccgtgg
    11821 ccgtcgcggt ccaccgggcg gccaccggct gagcaacgtg acattgtacg ctgggcgcct
    11881 gcggatactc ggaggaacgg cgtgggcgac ctgaagcagc acagtctcat caaggcccag
    11941 gagcggcttc gcgaccaggt gggccacgca ctgcgcgccg ccctcacggc cggtgagctg
    12001 aagcccggga ccgtctactc ggccccgggc ctcgcggccg agctcggcgt gtcggccacg
    12061 ccggtgcgcg aggccatgct cgacctggcc cgagagggcc tcgtcgagcc ggtccgcaac
    12121 aagggtttcc ggatcaccga ggtcagcgaa cgcgagctcg accagtgcac cgagctgcgg
    12181 atgctcatcg aggtgcccac ggtcggccgg gtcaccgaga ccgcgacggc cgagcagctg
    12241 gaggcgctgc gcccgctggc cgaggagatc gtggtcaacg cccgcgagca caacctcatc
    12301 ggctatctgg aggcggaccg gcagttccac ctcaccctcc tcggcctgtc cggcaacgac
    12361 cggctggtgg agaccgtggg cgacctgcgc aagcggtccc ggctctacgg gctgaccggt
    12421 ctggacgagg ccggcaagct ggtctcctcc gccgaggagc acgtcgaact gctcgacctg
    12481 atgatcgccc gcgaccgggc cggcgccgag gcgtgcatga tgcgccacct cggccacgtc
    12541 cgctcgctct gggccgaggc ccgggacgaa ccggtcgagc cggcggccgg cgccctgcgc
    12601 tcggtccgca agcgctgatc ccgtacgacg aacggcgcgc cgcactccgc gggggagtgc
    12661 ggcgcgccgt tcgcgtgggc gcgggcgggg atcagaccgc cggggccggg aaggtcgggt
    12721 actcgacgcc cgagacgtgc tggacgacgc ggatgacctg gcaggagtag ccgaactcgt
    12781 tgtcgtacca caggtacagg atcgcgttgt cgccgtcgac cttggtcgcg ccggcgtcca
    12841 cgatggaggc gtggcgcgag ccgacgaa
//
