LOCUS       NZ_JABBGE010000007     23306 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. R302 contig7, whole genome shotgun sequence.
ACCESSION   NZ_JABBGE010000007
VERSION     NZ_JABBGE010000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. R302
  ORGANISM  Streptomyces sp. R302
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 512609)
  AUTHORS   Dahal,R.H.
  TITLE     Streptomyces sp. R302 sp. nov., isolated from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 512609)
  AUTHORS   Dahal,R.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) Life Science, Kyonggi University, Kyonggi
            University, Suwon, Gyeonggi-Do 16227, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2020
            Assembly Method                   :: SPAdes v. APR-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012927245.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 03:52:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,357
            CDSs (total)                      :: 7,271
            Genes (coding)                    :: 7,075
            CDSs (with protein)               :: 7,075
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 84 of 196
            Pseudo Genes (incomplete)         :: 164 of 196
            Pseudo Genes (internal stop)      :: 20 of 196
            Pseudo Genes (multiple problems)  :: 67 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 258029
            Orig. end                         :: 281335
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBGE010000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23306
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..23306
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23306
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13306](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13306
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    complement(307..326)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.7"
                     /tool="antismash"
     misc_feature    654..672
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.65"
                     /tool="antismash"
     misc_feature    complement(655..671)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     gene            858..1232
                     /locus_tag="HHL19_RS22965"
                     /old_locus_tag="HHL19_22975"
     CDS             858..1232
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473703.1"
                     /locus_tag="HHL19_RS22965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_22975"
                     /product="hypothetical protein"
                     /protein_id="WP_169092183.1"
                     /transl_table=11
                     /translation="MVSVETSLKEAMTSIEGSVGAALVDYTSGMALGTLGGGKDLDLTV
                     AAAGNTDVVRAKLRAMEMLGIEDGIEDVLITLDTQYHLIRLLKGRGGNGLFLYIVLDKN
                     RANLAMARHQLKRIEAELEL"
     gene            1386..1745
                     /locus_tag="HHL19_RS22970"
                     /old_locus_tag="HHL19_22980"
     CDS             1386..1745
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563681.1"
                     /locus_tag="HHL19_RS22970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_22980"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_169092184.1"
                     /transl_table=11
                     /translation="MQVPLYQAKAEFFRMLGHPVRIRVLELLKDGPVPVRELLKDIDVE
                     PSNLSQQLAVLRRSGIVVSVRDGSTVSYALAGGDVADLLKAARRILTELLVGQSELLAE
                     LRHAESATAPPPRRG"
     gene            complement(1782..2060)
                     /locus_tag="HHL19_RS22975"
                     /old_locus_tag="HHL19_22985"
     CDS             complement(1782..2060)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024753.4"
                     /locus_tag="HHL19_RS22975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_22985"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_346768381.1"
                     /transl_table=11
                     /translation="MARWSLEDGAVHWLFDADAPVTALAGDEDTVYGAFGSGELVALRT
                     QDGGVRWRHRLELGGRAVVPLSLVRAGAGRVLIGAVDGRVLDVAAEG"
     gene            3071..5125
                     /locus_tag="HHL19_RS22980"
                     /old_locus_tag="HHL19_22990"
     CDS             3071..5125
                     /GO_function="GO:0004629 - phospholipase C activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017239178.1"
                     /locus_tag="HHL19_RS22980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_22990"
                     /product="phospholipase C, phosphocholine-specific"
                     /protein_id="WP_169092185.1"
                     /transl_table=11
                     /translation="MADLDRRRFLQLAGGAVAFSALSESIARAASIPAQGSTGTLQDVE
                     HIVVLMQENRSFDHYFGAMKGVRGFGDPRPVTLPSGKSVWNQADGKKVTLPFRPESAKL
                     GMEFLQGLNHDWAGGQKAFNNGRYDQWIPAKTKATMAHLTREDIPFHYALADAFTICDA
                     YHCSFIGSTDPNRYYLWSGHTGNDGTGGGPVLNNAEAGYGWKTYPERLEAAGVSWRIYQ
                     DIGDGLNAAGSWGWINDAYRGNYGDNSLLYFNSYRNAQPGSPLYEKARTGTNAKAGEGY
                     FDRLRADVQGGRLPQVSWIAAPEAFSEHSNWPSNYGAWYIAQVLDALTSNPDVWARTAL
                     FITYDENDGFFDHVVPPYVPASAAQGLSTTPTALDHFPGKTGYVAGPYGLGPRVPMIVV
                     SPWSTGGYTCSETFDHTSVIRFIERRFGVQEPQISPWRRAVCGDLTSAFDFGRAQPQPA
                     ALPSTAGYYPPDRDRHPDFLATAPAVGTMPRQEPGAKPTRPLAYAPYVDGSADTTAGTF
                     RLAFSGGPSAGAQFYVTSANRTDAPWTYTTGAGASIADTWNTKYSKGTTDLTVHGPNGF
                     LRRFRSPGKTAVPEVTARHDAATGSLRLTFTNAGADTTVTLVNAYAGGPQTLTVARGAT
                     VTHTVPLADSGRWYDVTVTSAAHADYVRRLAGHVETGAEGVTDPGILTY"
     gene            complement(5154..5546)
                     /locus_tag="HHL19_RS22985"
                     /old_locus_tag="HHL19_22995"
     CDS             complement(5154..5546)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015862.4"
                     /locus_tag="HHL19_RS22985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_22995"
                     /product="heme-binding protein"
                     /protein_id="WP_346768382.1"
                     /transl_table=11
                     /translation="MVTTAHLTERAAEKAARAALAAAVTVLDRSGNAFVVLRGDGAASH
                     TYESAHRKAYTAASFNAPTSVLVGRVEQSPTLAGIGIGIGIGIGIGIGHPHRRRRRAQR
                     SPRRGVRPGGRRRPRPLTPPRGRHTP"
     gene            complement(<6176..6970)
                     /locus_tag="HHL19_RS37620"
                     /old_locus_tag="HHL19_23000"
                     /pseudo=""
     CDS             complement(<6176..6970)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010636609.1"
                     /locus_tag="HHL19_RS37620"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23000"
                     /product="MerR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLIGEVARRSGVSARMLRHYEKLGLVRPSDRTGSGYREYRDEDIR
                     RIFHIESLRSLGLSLREIGRALDDPGFTPGRLVGDLIEQTRARIAAETELLTRLRRIDA
                     TEPAGWDDALRVVALLQALGSASKDTCQRAALAAADEIPVPVEALVEAALGETETNVAG
                     ALRWALARSGDGGPALLAHALDSPDPAVRERAVRILAGLPGADATTLLRTALTHPDPVV
                     GAQAALALGNRGDADAIPTLVEMVVDGRNDTDAADALAALATD"
     gene            complement(6974..7645)
                     /locus_tag="HHL19_RS22995"
                     /old_locus_tag="HHL19_23005"
     CDS             complement(6974..7645)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381637.1"
                     /locus_tag="HHL19_RS22995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23005"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_169092187.1"
                     /transl_table=11
                     /translation="MTTTYQDPEVGRALRALADDRPSVRLKAALAVGTTPDARFVDALV
                     ERCAVEPEFFVRDMLTWALTRHPESLTLPRVLAELGSERARARSQALHTLSKIGDRRAW
                     PAITRAHLTDTDDEVARAAWRTAVLLVPDGEEPALATVLAGQLGRGGRETQLSLSRALI
                     GLGDVILPVLDTAAAGPDPLVRAHALATRRILRDPDTGFEYAIEEAKRVVALDGSPGEG
                     H"
     gene            complement(7755..8207)
                     /locus_tag="HHL19_RS23000"
                     /old_locus_tag="HHL19_23010"
     CDS             complement(7755..8207)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988527.1"
                     /locus_tag="HHL19_RS23000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23010"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_169092188.1"
                     /transl_table=11
                     /translation="MDAMDRKILAELQQDGRLTVTELAARVRLSVSPCHRRLRDLERAG
                     AIRGYRAVVDPAAVGLNFEALVFATLRWEDPDTVTAFEEAVAAVPHVLQAQRLFGEPDY
                     LLRVATADLPAFQELYDQRLARLPGVQRLTSTLVMKHVVDDRPLPQ"
     gene            8328..9017
                     /locus_tag="HHL19_RS23005"
                     /old_locus_tag="HHL19_23015"
     CDS             8328..9017
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906723.1"
                     /locus_tag="HHL19_RS23005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23015"
                     /product="LysE family translocator"
                     /protein_id="WP_169092189.1"
                     /transl_table=11
                     /translation="MDTTTLAAFLAVDLLLVLTPGADWAYAISAGLRGRSVVPAVAGLV
                     AGYAGYTLLAVAGLVVLVASSPAVLTALTLAGACYLVWLGVGVLRQPAVLTASEETAGA
                     AAATGASGGTGVSGGTGVSGGTGVSGARLALRGMGISGLNPKALLLYFSLFPQFIDPAT
                     GWPVAAQTGLLGSLHMTACAVVYLGVGVLARTVLRGRPTAARAVTRVSGVMMIAIGALL
                     LAEHLAG"
     gene            complement(9048..9638)
                     /locus_tag="HHL19_RS23010"
                     /old_locus_tag="HHL19_23020"
     CDS             complement(9048..9638)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240186.1"
                     /locus_tag="HHL19_RS23010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23020"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_169092190.1"
                     /transl_table=11
                     /translation="MGKLIHFVHQSLDGYIEGPNGEFDWPAMGPELSAHSRELTPEGTL
                     FLYGRKVWDLMSGFWPQAERYSQDPHDLAFAPVWRKAPKIVVSRTLRQDALDEGALGEA
                     AHNTRLISDHAAEELTALKEAGHDLVLFGGSELAAHLTEHGVIDEYHVVVHPVLLGGGR
                     PAFHPAQARTPLALAGTRTFDGRAVLLVHTRTA"
     misc_feature    complement(9676..9688)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: medium, score: 23.79"
                     /tool="antismash"
     misc_feature    complement(9733..9747)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.08"
                     /tool="antismash"
     misc_feature    9734..9748
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.16"
                     /tool="antismash"
     gene            10001..13306
                     /gene="lanL"
                     /locus_tag="HHL19_RS23015"
                     /old_locus_tag="HHL19_23025"
     CDS             10001..13306
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104908.1"
                     /locus_tag="HHL19_RS23015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23025"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_169092191.1"
                     /sec_met_domain="Pkinase (E-value: 1.1e-18, bitscore: 62.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-43, bitscore:
                     143.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSHATEALLEDLLHRALLATDTGGRWATRSDDMWCRVTPLDGEQ
                     RPQGWKLHVSATAASAPAVLLKSLEVLLPDASGFKFARSLERVGALNSRATPRGSSGKF
                     LTVYPRSDADAARLAAELHRATAGLAGPRILSDQQYAADSLVHYRYGAFVGRRRLSDDG
                     LLVWYFEDPDGNPVEDRRTGRYTPPEWAVSPFPAPAHVPSPAPAPTAAAPRPVVVGGRF
                     SVREAIRHTNKGGVYRGSDVRTGAPVVIKETRPHVEADASGSDVRDWLRAEARTLEKLR
                     GSGLAPEPLALFEHGGHLFLAQEEVPGVPLRTWVAERFRDLGGERYGAEATAQVARLVD
                     LVAAAHEHGCVLRDFTPGNVMVRPDGELRLIDLELAVLADDAALPTRVGTPGFSAPERL
                     LDAPVSPTADYYSLGATVCFVLAGKVPNLLPEEPQHRPAEERLAEWLDASLVSVRLPEG
                     IRESILGLMRDDPNARWDPGRAREALGLTDGGKTAGVSPVGGPAAARSTAGGPTAARSG
                     AGGKQAGGPTAAPSNTDGPTASGPTATPSTTNGSAAGRSTAGGPTAARSTAGGQQASEP
                     TATRSTIGGSAAGRATSGGPTADGSTADRSTANGSTADGSTANRSTSDGPTAGGPTAGG
                     PGAAGSTAGGPTAAELPAVVPTARPSRPSSAGSAAPPAACAAPLDPPTTNVPPTPLSPP
                     TTNAPSAALSPPPACAPACGDAIGTAVDGIVRHLVDTMTPGDDRRLWPVSTLAGESDPC
                     SVQQGAAGVLAVLTRYFELTGDPRLPGPLAVAGRWIAERTEPRSARPGLHFGTGGTAWA
                     LYEAGRAVGDRALVDHALALAVAPQRPTPSHDITHGTAGSGMASVHLWRRTGDPRLAAL
                     VGEAADRLAEAARREASGVSWPVPAEAVAEEAGKRYLGFAHGSSGIGCFLLAAASVTGS
                     PVHRELAVAAGEHLVAHAVDVGGAAQWPAQTGDVPTAPYWCHGSAGIGSFLVRLWRATG
                     DDRFGSLARAAGRAVVERASRAALTQCHGLAGNGDFLLDLAEATGDPAHRARAGDLARL
                     LLAERSLRGGHVVFPNEYGEVSTGWSDGSAGILAFLLRVRHTEPRHWMVQLPV"
     misc_feature    10025..10027
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13387..13542
                     /locus_tag="HHL19_RS23020"
                     /old_locus_tag="HHL19_23030"
     CDS             13387..13542
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031827.1"
                     /locus_tag="HHL19_RS23020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23030"
                     /product="VenA family class IV lanthipeptide"
                     /protein_id="WP_169092192.1"
                     /transl_table=11
                     /translation="MENKDLELLAQLHALPETDPVGVDGAPFAATCECVGLLTLLNTVC
                     IGVSCA"
     gene            13644..14684
                     /locus_tag="HHL19_RS23025"
                     /old_locus_tag="HHL19_23035"
     CDS             13644..14684
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104906.1"
                     /locus_tag="HHL19_RS23025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23035"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_169092193.1"
                     /transl_table=11
                     /translation="MPLHPGDHDSPRTAAARTAPPAASVPSAIRTRGLVKSYRGPDGAP
                     VHAVRGLDLDVRQGETFAFLGPNGAGKSTTIAMLCALTRPTSGSATVAGADVLTEPDLV
                     RGRVGLLFQHSALDTDLTAEQNLRVHARLYGLRRGEARRRTAEALDVAGLSDRRRAPVR
                     TLSGGMRRRLELARQLLHSPGVLFLDEPTTGLDPHARVLVRDHLRTLRDRHGSTLFVTT
                     HYLDEAEHCDRLAIVDRGRLVAQGTPYDVKAAIGDDRVALRTSDDAGARRVVVPLAPPG
                     RPVTVDADGLWLRVPHGSTWIPRLCAALGSHGIDVHAASATPPTLDDVFFHHTGRSMAP
                     DEGGGR"
     gene            14681..15547
                     /locus_tag="HHL19_RS23030"
                     /old_locus_tag="HHL19_23040"
     CDS             14681..15547
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955215.1"
                     /locus_tag="HHL19_RS23030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23040"
                     /product="ABC transporter permease"
                     /protein_id="WP_169092194.1"
                     /transl_table=11
                     /translation="MTTTATGGRVGIDTCTGTGTGTGLRRELRAVHALVHRDLLRLACQ
                     RIPTALMLLHPVLYLFILGGGLAALIPTTSLGVGYRTYLFPGMLMMTVQTPAIMVGIRL
                     ITDRQSGYLRELLMAPVGRTTLLLGSCAGGTLVATVQGAVLLLLAGAVGLPYDPVLLVL
                     LLGGLVLASFAITALSLALAVGLRSPETFHTLLGLVMMPLLFLSGGFFPLTSLPGWAQA
                     LAAANPLAYGVDVLRRSIALRAPEQAAADGLAWAGHPPPLLLEAGLLLAAGAAALTWAA
                     RRFGRPE"
     gene            complement(15810..16436)
                     /locus_tag="HHL19_RS23035"
                     /old_locus_tag="HHL19_23045"
     CDS             complement(15810..16436)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS23035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_23045"
                     /product="hypothetical protein"
                     /protein_id="WP_169092195.1"
                     /transl_table=11
                     /translation="MTSCAGAESPERTPKTSSASPTPSATASATATATESVEEAVAAAA
                     EQMRTAATGRNAPGPQGLLVAAESTGGALFVWETPDGRFCHGAAKPVGMTMVACASAPH
                     TPPVGEKPRIIPLVTMMATGWNVVFGAEHETVESVTCNGVPLPVKDVGVVADGRRSVHA
                     IEFPDLTLGTVDVRVRRGSRVVTESLSLMSSWKEGKGNFAICGKP"
     gene            16545..16922
                     /locus_tag="HHL19_RS23040"
                     /old_locus_tag="HHL19_23050"
     CDS             16545..16922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089655.1"
                     /locus_tag="HHL19_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23050"
                     /product="VOC family protein"
                     /protein_id="WP_169092196.1"
                     /transl_table=11
                     /translation="MIGTLQCVVLDCPDVMELARFYASLVGGEVNRPDARWSLGDDWAT
                     VHADGGLVLAFQRVAEYRAPRWPDPGHPQQFHLDLGVADLDRAGAEVLALGATLLDGGD
                     GKRSWRVYADPAGHPFCLVRD"
     gene            17066..17746
                     /locus_tag="HHL19_RS23045"
                     /old_locus_tag="HHL19_23055"
     CDS             17066..17746
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676957.1"
                     /locus_tag="HHL19_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23055"
                     /product="beta-glucanase"
                     /protein_id="WP_169092197.1"
                     /transl_table=11
                     /translation="MSVPYPPSPDEPVFAADFGSPSQWVAGRTWAYPDGGPVNPLDNKL
                     DHLVDDPAYCRSGVFRATRRPDGLWDSGLLTTEGSEEGFEVRAGDVLEARVRLPSETGA
                     WPAIWTWRDGGQEVDVFEYHPDNPDLLELSNRVRGTHHYHRSPDVRPGEWVELRTEFGA
                     RSVVWWVNGTAVFADGRGVGRSWHACLIVNLSVCAGRYHPAPDPGTTEMSFEVADLRVL
                     RSRW"
     gene            complement(17833..18492)
                     /locus_tag="HHL19_RS23050"
                     /old_locus_tag="HHL19_23060"
     CDS             complement(17833..18492)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017242062.1"
                     /locus_tag="HHL19_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23060"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_240981812.1"
                     /transl_table=11
                     /translation="MATRPILADLCAHLRLADGTRIRFESAGGVEIARRVREGTEADLL
                     VLAADAVTALEEAGHLAPGTARPLWRSQVVAAVPAQAPALPLDTVGDLRTALTSATAIA
                     YSTGPSGTALLDLLHRLALADTLTDRLVQAPPGVPAGTLLASGRADLAFQQHSELMDLP
                     GVTVLGPLPGDTAITSLFTAAVLATTTAPAHAQEALALLTGDEATRRAEARGMARA"
     gene            18629..19396
                     /locus_tag="HHL19_RS23055"
                     /old_locus_tag="HHL19_23065"
     CDS             18629..19396
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017242063.1"
                     /locus_tag="HHL19_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23065"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_346768383.1"
                     /transl_table=11
                     /translation="MSTTRSTAAGKVLEVLAVFDREHPAQTLSEIAQRTGLALSTAHRV
                     VMELAAWGALERGEDGAWHVGLRLWEIASGCPRTQILRDVALPFMQDLYEVTHENVQLA
                     VREGTELVFVERIAGHRSVELLTGVGTRFPVGATGMGRVLLAHAPGDIQEEVLGAPQRA
                     WTPHTVTDPRTLRAQLDRIRREQVFVSDRQLSESTVAVAAPVRIGRSGPVSAALGIVVT
                     AEGADRAHRLREPLLRAAYGISDELGRRTRTTE"
     misc_feature    complement(19468..19486)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.66"
                     /tool="antismash"
     gene            19511..20719
                     /locus_tag="HHL19_RS23060"
                     /old_locus_tag="HHL19_23070"
     CDS             19511..20719
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020555230.1"
                     /locus_tag="HHL19_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23070"
                     /product="4-hydroxybenzoate 3-monooxygenase"
                     /protein_id="WP_169092200.1"
                     /transl_table=11
                     /translation="MADAPVDSVVSVPVAVVGAGPAGLMLAHLLGRAGVEAVAVDTRTR
                     HGIETTQRAGILEADVARDLVDTGVSDRILRDGYEHEGIEVRSGGRPYRIDFKKLVGAS
                     TWLYPQTDVFVDLADARERDGGTVHFGIRDTEVLDVTTDAPRVRYTAPDGTRHEIRARY
                     VVGADGSRSMCRDLVPEGRRTRYGKEYPFAWFGILAEAPRSAPELVYARSEHGFALISQ
                     RTEAVQRMYFQCSPDESADAWSDDRIWETLQARVAGEDGFRLKEGPITEKTVLRFRSFV
                     QEPMRWGSLLLAGDAAHTVPPTGARGLNLALHDVKVLAEVLLKALGGAGETALEEYEPR
                     ALRRIWRAQNFSYWMTRLLHTAPGASAFDLRRQLGELENVVGTRAGRTYLAEQYTGWPT
                     RDH"
     gene            20751..21776
                     /locus_tag="HHL19_RS23065"
                     /old_locus_tag="HHL19_23075"
     CDS             20751..21776
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470004.1"
                     /locus_tag="HHL19_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23075"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_169092201.1"
                     /transl_table=11
                     /translation="MIIDCHGHFTTAPPKLAAWRERQIAAAEGRGPLPDPDELVITDDE
                     LRAAVEGNQLRLMDERGSDLTVFSPRASFMAHHIGDFAVSSVWARICNDLVHRVAALYP
                     DRFATGAMLPQSPGVDPATCLPELTRAVEELGAVTVNLNPDPSGGRWSAPPLTDRSWYP
                     LYEAMTAYDIPAMIHVSTSCNPAFHTTGAHYLNADTTAFMQLVQGDLFADFPTLRFVIP
                     HGGGAVPYHWGRFRGLAMALGRPDPEALLDNVFFDTCVYHQAGVDLLTRVIPSRSVLFA
                     SEMIGAVRDVDPRTGHHFDDTKRYVDATPHLSDGERAAVYSGNALRVYPRLAARLAAAG
                     R"
     gene            21794..22489
                     /gene="ligK"
                     /locus_tag="HHL19_RS23070"
                     /old_locus_tag="HHL19_23080"
     CDS             21794..22489
                     /EC_number="4.1.1.112"
                     /EC_number="4.1.3.17"
                     /GO_function="GO:0047443 -
                     4-hydroxy-4-methyl-2-oxoglutarate aldolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ligK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044085.1"
                     /locus_tag="HHL19_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_23080"
                     /product="4-carboxy-4-hydroxy-2-oxoadipate
                     aldolase/oxaloacetate decarboxylase"
                     /protein_id="WP_169092202.1"
                     /transl_table=11
                     /translation="MEHTEIGVVRTHVERAAPEAVAELSKYGVATIHEAMGRVGLMRPY
                     LRPVYPKARMCGTAVTVLLQPGDNWMLHVAAEQIRDGDVVVAACTTESEDGFFGELLAT
                     SFRARGCRGLVIDGGVRDVADLEGMDFPVFSRAVNAKGTVKATLGSVNVPVVCGNALVR
                     PGDVVVADADGVVVVPRERAAGVAAAAAAREAAEEGKRAQFRAGKLGLDLYGMRGPLAS
                     LGLRYEDGR"
     misc_feature    complement(23107..23121)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.08"
                     /tool="antismash"
     misc_feature    23119..23129
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
ORIGIN
        1 gtgggcgagg cctggtcgat gccggcgagc tgggcggtga tggtggcgcg cagctcgtcg
       61 tcgtcctgga accagtggtc gtggaagagg gtgtagccgg tccacatcag gttggcgcac
      121 acccgggcgg ggacgcggcc ggtgcgggct cccatcccga ccagggcgac cgagcggatg
      181 ctgccgggcg ccttgcggtt ctgccggtgg acggcctgga aggcggcggc gcaggccatg
      241 gcgacgttca gcgtctcgct cacgttctgc gacgaggcga ccatggtcgg cgtcgagatg
      301 acgaagcgcg ggacggtcgc ccccgagggg acgcacaccg cgctgccgac cggcatgctg
      361 ccgtcgaagc ggtcggcgat cgccttgcgg accctcagct ggatacccgc gcccaggtgg
      421 cgcttgatga cggcgtcgac gccgccgtcc atgctgcccg ccgcgttcgt cggcgtgacc
      481 caggcgtcca cgtcctcgtc gaggatggaa ccccggcgga tctcgatgcc gggaacgtcg
      541 gcgaaggcgg cgcgccaggc ctgcaccacc cccgcgttga catccgtcag caccacccgc
      601 agcgcggtgt ccacacagcc gtcggtcatc gaagccccct gtcggaacgg tgtcgtgcga
      661 ctctctcgca acacctccga agctagtggg caccactgac aacgccgttc ggggcctatg
      721 cccgaggcat cgtcttccgg cgaaagccct ctgccctcgg cgtctttggt gtctagtgga
      781 cctcgtccgt gagcaccacc cggccgtggg ggtctgccgc cggtccggga tgtccagaac
      841 tgagggagca cgtactgatg gtgagtgtgg aaacgtctct gaaggaggcg atgacctcca
      901 tcgaggggag cgtgggggcg gcgctggtcg actacacgag cggcatggcg ctcggcacgc
      961 tcggcggggg caaggacctc gacctgaccg tggcggcggc cggcaacacc gacgtcgtcc
     1021 gggcgaagct gcgggcgatg gagatgctgg gcatcgagga cggcatcgag gacgtcctga
     1081 tcaccctcga cacccagtac cacctcatcc ggctgctcaa gggccggggc ggcaacggcc
     1141 tgttcctgta catcgtcctg gacaagaacc gcgcgaatct ggccatggca cggcaccagc
     1201 tgaagcgcat cgaggcggag ctggagctgt aaccgtcccc ctgactcccg gctccgcacg
     1261 cccacgactt gaagaagtct tcaagtcgac acatccgaaa gtgacgcagt cgagggcgtg
     1321 cggacgccgg gacacgggag gatgggcccg tcagcacagg tcagaacgtc ggggagagtc
     1381 gtcgcatgca ggtgccgctg taccaggcca aggcggagtt cttccgcatg ctcgggcatc
     1441 cggtccggat ccgcgtcctg gaactgctca aggacggccc tgttcccgtg cgcgagctcc
     1501 tcaaggacat cgacgtcgag ccgtccaacc tcagccagca gctggccgtc ctgcgccgct
     1561 cgggcatcgt ggtctccgtc cgcgacggct ccaccgtcag ctacgcactc gccggcggcg
     1621 acgtcgccga cctcctcaag gccgcccgcc gcatcctcac cgaactgctc gtcggccaga
     1681 gcgaactcct cgccgaactc cgccacgccg agagtgccac cgccccgccc ccacggcgcg
     1741 gctgaacgga cccggcgatc ccgccgccgc gcccaccgac gtcagccctc cgcggccacg
     1801 tcgaggaccc gcccgtccac ggccccgatc agcaccctcc ccgccccggc gcggacgagc
     1861 gagagcggta cgacggcccg cccgccgagc tccagccggt gccgccaccg cactcctccg
     1921 tcttgggtgc gcagcgccac gagctcgccc gagccgaagg cgccgtagac cgtgtcctcg
     1981 tccccggcca gggcggtgac gggggcatcg gcgtcgaaga gccagtgcac ggctccgtcc
     2041 tcaaggctcc acctggccac gaaggatgga ggcgcaggcc gcgccccgcg tcccagtcac
     2101 gggggaacag ctgccgtacg gtgggggcgc cgtcggggcc ggacggatcg acggccacca
     2161 cccactggtc gttccacggc tcacccaacg caccctggag cgcgatcagt tgccgtgcgt
     2221 ggcggacggg gagggcgttg tcgacggcgt cgaaggctcc caccgacgcg tacgactccg
     2281 gagccgtacg cgtcgggccg gtcagcgcgg ccggctccgg ggcgcgcctg tcgccgctcg
     2341 cggggcgggg cagcagccag ccgtcgtcgg gagccctcag ggccgtacgg aatccgggat
     2401 gcaggaggtc gagcaccgtt ccctccggga gggagggtct cgccgcgcaa ggcggtacga
     2461 cgacctgctc ccgacccgcc cagcgcacgc gccgacgctc cacgttcacc caggcctcgc
     2521 gctcgccgtc cctcacgacg agctgtcggc cgccctcgtc gtccggaacg cgccagtggg
     2581 gtcgctagtc cggcagccac gcctcggcga gtactccgtc cagacaggcc acgacccgcc
     2641 cgtcccgcag gccgtggacg tcccagaccc gacgacgcgg ctcccagtcg ggctccccgt
     2701 gggacgtcgc tccggtcgac ggcctcgacg acggcttcgt agcacctcgc gccgtccctg
     2761 aagggcccga ggccacccgg ccggacccga gatcgatcag cagctcgccg tcgtagaacc
     2821 accctccgtc gaacgatccg gccgcgcttc tcgccgacgg tcaccgccga gggcacgccc
     2881 acatcggcgc aagcggtcag gggtgggttc cggtgcttcc ggggtgtggg ggatttcttc
     2941 gggtgtacag cgggaagtca cgggacggtc gtggggtggt ggttctcggg cgctcttctt
     3001 ggggcgctcc gcgccggtcc gtggccggcg ctcggttccc gtgtccgctc gtcttccgga
     3061 ggcttccccc atggccgatc tcgatcgtcg caggtttctt cagctggcgg gtggtgccgt
     3121 cgcgttcagc gcgctgtccg agtccatcgc ccgggccgcg tcgattcccg cgcaggggtc
     3181 caccggcacc cttcaggacg tcgagcacat cgtcgtactg atgcaggaga atcgttcctt
     3241 cgatcattac ttcggggcga tgaagggggt gcgcgggttc ggcgacccgc ggccggtgac
     3301 gctgccgagc gggaagtcgg tgtggaacca agccgacgga aagaaggtga cgctgccgtt
     3361 ccgtccggag agcgcgaagc tggggatgga gttcctccag gggctcaacc acgactgggc
     3421 gggtggccag aaggcgttca acaacgggcg ctacgaccag tggattccgg ccaagaccaa
     3481 ggcgacgatg gcgcacctga cccgggagga catccccttc cactacgcgc tcgccgacgc
     3541 gttcaccatc tgcgacgcgt accactgctc gttcatcggc tcgaccgacc cgaaccgcta
     3601 ctacctgtgg tcggggcaca ccggcaacga cggcaccggc ggcgggccgg tgctcaacaa
     3661 cgccgaggcc gggtacgggt ggaagacgta tcccgagcgc ctggaggcgg ccggggtctc
     3721 ctggcggatc taccaggaca tcggcgacgg gctcaacgcg gccggctcct ggggctggat
     3781 caacgacgcg taccggggta actacggcga caactcgctg ctctacttca acagttaccg
     3841 gaacgcgcag cctggcagcc ccctgtacga gaaggcgcgg acggggacca acgccaaggc
     3901 gggagaaggg tacttcgacc ggctgcgcgc cgacgtgcag ggcgggcgac tgccgcaggt
     3961 ctcctggatc gccgcccccg aggccttctc cgagcactcc aactggccct cgaactacgg
     4021 cgcctggtac atcgcccagg ttctggacgc gctgacctcg aacccggacg tgtgggcgcg
     4081 tacggcgctg ttcatcacct acgacgagaa cgacggcttc ttcgaccacg tcgtcccgcc
     4141 gtacgtcccg gcctcggcgg cgcagggcct gtcgaccacg ccgaccgccc tggaccactt
     4201 ccccgggaag acggggtacg tcgccgggcc ctacggcctc ggcccccgtg tccccatgat
     4261 cgtcgtctcc ccatggtcca ccggcggcta cacctgctcc gagaccttcg accacacctc
     4321 ggtcatccgc ttcatcgagc gccgcttcgg cgtccaggaa ccgcagatct cgccctggcg
     4381 gcgggccgtc tgcggcgacc tgacctcggc cttcgacttc ggccgcgccc agccgcagcc
     4441 ggccgcgctg ccgtccacgg ccggctacta cccgccggac cgcgaccgcc acccggactt
     4501 cctcgccacc gcgccggccg tggggacgat gccgcgtcag gagcccgggg cgaagccgac
     4561 gcgtccgctg gcgtacgccc cgtatgtcga cggctccgcc gacacgacgg ccggcacctt
     4621 ccgcctcgcc ttcagcggcg gcccgtccgc cggcgcccag ttctacgtga cgtccgcgaa
     4681 ccgcaccgac gcgccctgga cgtacacgac cggcgcgggc gcgtcgatcg cggacacctg
     4741 gaacaccaag tactccaagg gcaccaccga cctcaccgtg cacggcccca acggcttcct
     4801 gcgccgcttc cgctcgccgg ggaagacggc cgtcccggag gtcaccgccc gccacgacgc
     4861 cgccaccggc tccctgcgcc tcaccttcac caacgccggc gccgacacga cggtgaccct
     4921 cgtcaacgcc tacgcgggcg gcccgcagac gctgacggtg gcccgcggcg cgaccgtcac
     4981 ccacaccgtg ccgctcgccg actccggccg gtggtacgac gtcacggtca cctcggccgc
     5041 ccacgccgac tacgtccgcc gcctggccgg gcacgtggag acgggcgcgg agggtgtgac
     5101 ggacccgggc atcctcacgt actgactcgc ccgggggggg cggcacgcgc gcgtcacggc
     5161 gtgtgccgcc cccgtggggg tgtcagtggc cgagggcgtc gacgcccgcc tgggcgaact
     5221 cctcgtcgag gagaccgctg ggcgcgccgg cgacgccgat gcggatggcc gatgcctatg
     5281 cctatgccta tgcctatgcc tatgcctatg ccggcgagcg tcgggctctg ttcgacgcgg
     5341 ccgacgagga ccgacgtcgg ggcgttgaac gacgccgccg tgtacgcctt ccggtgcgcg
     5401 gactcgtacg tgtgggatgc cgcgccgtcg ccgcgcagga cgacgaacgc gttgccgctg
     5461 cggtccagga cggtgacggc cgccgccagc gcggcgcgcg cggccttctc ggcggcccgc
     5521 tccgtcaggt gcgcggtcgt gaccacgttc tggggtgcga cgccgccgac cggcaggggg
     5581 cgtcggccgt cgccggcgcg gggacggcca ggccgaggcc ccggccgatc gccatcaagg
     5641 tgccgcaggc cgcgacgcgt acacccggcg tggatctctc cacggacact cccggcccgg
     5701 tcgcggcggc ctgcggggcg cgggccaccg acactgcccg cccggccggg gtgggggtgg
     5761 gtcagcggcc gtcccggagg cggagcaggt acgtcgcggt cagcgcgacg ccggggtccg
     5821 cgtcccgcgt gagaccggcg agggcgcggg cggcgacggg cccggggatg tccgcgaggg
     5881 cctgggtaag ccgaccccgg gcggcggagg cgctggccgc gtcagcgtct ggggcggcac
     5941 cagcggcgac ggggtcgctg accgggtcgg cggcggaggc gccgtcgtcg gcggcggcga
     6001 cacgggcgat ggccggggcg gcggaggcgg cgtcggcgtc tggggcggcg gaggcgtctg
     6061 gagcggaggc gtcggcgtct cgggtggcgg agggggcgtc tggggtggcg gtggcggcgt
     6121 ctcgggtggt gagtcgggtg aggagttcgg ttgcgatggc gtcgccctgg gtgtcgtcgg
     6181 tggccagggc ggcgagcgcg tcggccgcgt cggtgtcgtt gcggccgtcg acgaccatct
     6241 cgacgagcgt ggggatcgcg tcggcgtcgc cccggttgcc gagcgcgagg gccgcctggg
     6301 ccccgaccac cgggtcgggg tgggtgaggg ccgtgcggag caaggtggtc gcgtccgcgc
     6361 cggggagccc ggcgaggatg cggacggcgc gttcgcgtac cgcggggtcc ggcgagtcca
     6421 gggcgtgggc gaggagggcg gggccgccgt cgccggagcg ggcgagcgcc cagcggaggg
     6481 cgcccgcgac gttggtctcc gtctcgccga gggcggcctc cacgagtgcc tccaccggta
     6541 cggggatctc gtcggcggcg gcgagcgcgg cgcgctggca ggtgtccttg ctcgccgagc
     6601 cgagggcctg gagcagtgcc acgacccgca gggcgtcgtc ccagcccgcg ggttcggtgg
     6661 cgtcgatgcg gcgcagccgg gtgagcagtt cggtctcggc ggcgatgcgg gcgcgggtct
     6721 gctcgatgag gtcgccgacg agccgcccgg gcgtgaagcc ggggtcgtcg agggcgcggc
     6781 cgatctcccg cagcgacagc cccagcgagc ggaggctctc gatgtggaag atccgccgga
     6841 tgtcctcgtc gcggtactcc cggtagccgg atccggtgcg gtccgagggc cgcaccaggc
     6901 cgagcttctc gtagtgcctg agcatgcggg cgctgacgcc ggagcgacgc gccacttcac
     6961 cgatcaacac gccctagtgt ccctcccccg gggacccgtc gagcgccacg acgcgcttcg
     7021 cctcctcgat cgcgtactcg aatccggtgt cggggtcgcg caggatccgc cgggtggcga
     7081 gggcgtgggc gcgcaccagc gggtcggggc cggccgccgc ggtgtccagg accgggagga
     7141 tcacgtcgcc gagcccgatc agcgcccggc tcaggctgag ctgcgtctcc cgtccgccgc
     7201 gccccagctg gccggcgagg acggtggcga gggcgggctc ctcgccgtcc ggcacgagca
     7261 ggacggccgt ccgccaggcg gccctggcca cctcgtcgtc ggtgtcggtg aggtgcgcgc
     7321 gggtgatcgc cggccaggcc cgccggtcgc cgatcttgga cagggtgtgc agggcctggc
     7381 tccgtgcccg cgcccgctcc gagccgagct cggcgagcac gcggggcagc gtcagggact
     7441 cggggtgcct ggtcagggcc caggtcagca tgtcgcggac gaagaactcg ggctcgacgg
     7501 cgcaccgctc gacgagcgcg tcgacgaacc gcgcgtcggg cgtcgtgccg accgccaggg
     7561 cggccttgag ccgcaccgac gggcggtcgt ccgcgagcgc ccggagcgcg cggcctacct
     7621 ctgggtcctg atacgtcgtg gtcatcggga ccacctcctc gcccggcagt caaaggcttg
     7681 tcaccgtgtc aaggtcaagc gcgcgccacc ggtgccgtgc cggctaccgc cggtgccgtg
     7741 cgggcgaccg gcggtcactg gggcaggggc cggtcgtcga cgacgtgctt catgacgagg
     7801 gtggaggtca ggcgctggac gccggggagg cgggcgagcc gctggtcgta gagctcctgg
     7861 aaggcgggga ggtcggcggt ggccacgcgc aggaggtagt cgggctcgcc gaagaggcgc
     7921 tgggcctgga ggacgtgggg gacggccgcg acggcctcct caaaggcggt gacggtgtcg
     7981 gggtcctccc agcggagggt ggcgaagacg agcgcctcga agttcagacc gacggccgcc
     8041 ggatccacga cggcgcggta gccgcggatc gctccggcgc gttcgaggtc gcgcagccgg
     8101 cggtggcagg gcgagacgct gagccgcacg cgggcggcga gctcggtgac ggtcagacgg
     8161 ccgtcctgct gcagctcggc aagaatcttc cggtccatgg catccatgag ggaaattctc
     8221 ccctatatgc gacctcagcg gggtaaagaa gggaacactt tcgggcatat cccgcctagc
     8281 cttcctcacg tcatacggca cgtgagcacg tgagagggcc cgaaccattg gacacgacca
     8341 cactggcggc cttcctggcc gtggacctgc tgctggtcct cacgccgggc gcggactggg
     8401 cgtacgcgat ctcagccgga ctgcgcggac ggtcggtcgt gcccgccgtc gccgggctcg
     8461 tcgccggcta cgcggggtac accctgctcg ccgtcgcggg cctggtcgtc ctcgtcgcga
     8521 gctcgccggc cgtcctcacc gcgctcaccc tggccggcgc ctgctacctc gtctggctgg
     8581 gcgtcggcgt gctccggcag ccggccgtcc tgacggcctc cgaggagacc gcgggggcag
     8641 cggcggccac gggggcctcc gggggcacag gggtgtccgg gggcacaggg gtgtccgggg
     8701 gcacgggggt gtccggggcg cggctcgcgc tgcgcggaat ggggatcagc ggcctcaacc
     8761 cgaaggcgct gctgctgtac ttctccctct tcccgcagtt catcgacccg gcgacgggct
     8821 ggccggtggc cgcgcagacc ggtctcctcg gctcgctcca catgacggcc tgcgccgtcg
     8881 tctacctcgg cgtcggcgtc ctcgcccgca cggtgctgcg cggccggccc accgccgcgc
     8941 gcgcggtgac gcgggtctcc ggcgtcatga tgatcgccat cggcgccctg ctgctggccg
     9001 agcacctggc gggctgacgg gccgccggtg tcccgctccc tcctccgtca ggccgtgcgg
     9061 gtgtggacga ggaggacggc acgcccgtcg aaggtgcgcg tcccggcgag ggcgagcggg
     9121 gtgcgggcct gtgcggggtg gaaggcgggc cggccgccgc cgaggaggac ggggtggacg
     9181 acgacgtggt actcgtcgat gacgccgtgc tccgtgaggt gggcggcgag ctccgagcct
     9241 ccgaagagga ccaggtcgtg gccggcctcc ttcagggcgg tcagctcctc ggccgcgtgg
     9301 tcggagatca ggcgggtgtt gtgcgcggcc tcgcccaagg cgccttcgtc cagggcgtcc
     9361 tggcgcaggg tgcgggagac gacgatcttg ggcgccttgc gccagaccgg cgcgaaggcc
     9421 aggtcgtgcg ggtcctgcga gtaccgctcg gcctgcggcc agaagccgga catcaggtcc
     9481 cacaccttgc ggccgtagag gaagagcgtg ccctccggag tcagttcccg cgagtgggcg
     9541 gagagttccg ggcccatcgc cggccagtcg aactcgccgt tcgggccctc gatgtaaccg
     9601 tcgagggact ggtgcacgaa gtgaatgagc ttgcccatgg tgtcgaccga tcctcaggtg
     9661 tacgccggtg cccctgtgac accgtcaccc ctgggtcgga gccgcgaagg cgggctctac
     9721 atccggcgcg acactttccc ggaaaatttt cccggggcat gcccgcagac tgctccccgg
     9781 cacggccgac gcccaactcg cgtgcgccga aggcctggtc aggagggttt ggaaccccct
     9841 ggtgagctgc tgtgcgccgt tccgctccgg tcgcacctca gggtgggaca actacggcgc
     9901 gcgctcggcg gaaccggtga atccggcacc ggatatgtgg gtccgacacg tgcgccgggc
     9961 acgttcccgc cagcggttgc caccgtcgag agggatgggc atgacgagcc acgccaccga
    10021 agccttactc gaagacctcc tccaccgggc cctgctcgcc acggacacgg gcgggcgctg
    10081 ggccaccagg tccgacgaca tgtggtgccg ggtgacgccc ctcgacgggg agcagcggcc
    10141 tcagggttgg aagctgcacg tgtcggcgac ggccgcctcg gcgcccgccg tcctcctgaa
    10201 gtcccttgag gtgctcctcc cggacgcctc gggattcaag ttcgcccgct cgcttgagcg
    10261 ggtcggcgcg ctcaactccc gtgccacacc gcgcggcagc tccgggaagt tcctgacggt
    10321 gtacccgcgc tccgacgccg acgcggcccg cctcgccgcg gagctgcacc gagcgacggc
    10381 gggactcgcc ggcccccgga tcctctccga ccagcagtac gccgccgaca gcctggtcca
    10441 ctaccggtac ggcgccttcg tcggccggcg gcggctgtcg gacgacggcc tgctggtctg
    10501 gtacttcgag gaccccgacg gcaatccggt ggaggaccgg cgcaccgggc ggtacacgcc
    10561 cccggagtgg gccgtcagcc ccttccccgc cccggcccac gtcccctccc ccgcccccgc
    10621 cccgactgcc gccgcgcccc gcccggtggt cgtcggcggc cggttctcgg tacgggaggc
    10681 gatccggcac accaacaagg gcggtgtgta ccggggcagc gacgtccgca ccggcgcgcc
    10741 cgtcgtcatc aaggagaccc gcccgcacgt cgaggccgac gcctccggca gcgacgtccg
    10801 ggactggctg cgcgccgagg cgcggacgct ggagaagctg cggggctcgg ggctcgcgcc
    10861 cgagccgctg gccctgttcg agcacggcgg gcacctgttc ctcgcacagg aggaggtacc
    10921 gggcgtcccg ctgcggacct gggtagccga gcgtttccgc gacctcggcg gcgagcggta
    10981 cggggccgag gcgacggccc aggtcgcgcg cctcgtcgac ctcgtggcgg cggcccacga
    11041 acacggctgc gtgctgcgcg acttcacgcc cggcaacgtg atggtccgcc cggacggcga
    11101 actgcgcctg atcgacctgg aactggccgt cctcgcggac gacgccgccc tcccgacccg
    11161 ggtgggcacg cccggcttca gcgcccccga gcgcctcctc gacgcgccgg tctccccgac
    11221 cgccgactac tacagcctcg gcgcgaccgt gtgcttcgtc ctcgcgggca aggtgccgaa
    11281 cctgctgccc gaggagccgc agcaccggcc ggcggaggag cggctggccg agtggctgga
    11341 cgcctctctc gtctccgtac gactcccgga aggaatacgg gagtcgatcc tcggcctgat
    11401 gcgcgacgat ccgaacgccc gctgggaccc gggcagggcc cgggaggccc tcgggctgac
    11461 ggacggcggg aagacggccg gtgtgtcgcc ggtcggcggg ccggcagcag cgcggtcgac
    11521 ggccggtggg ccgactgccg cccggtcggg ggcaggtggg aagcaagccg gcgggccgac
    11581 agccgccccg tcgaataccg acggtccgac agccagcggg ccgacagcca ctccatcaac
    11641 caccaacggg tcggctgccg gaagatcaac ggccggtggg ccaactgccg cccggtctac
    11701 ggccggtggg cagcaagcca gcgagccgac agccactcgg tcaactatcg gcgggtcggc
    11761 tgccggccgg gcaacgtccg gtgggccaac ggccgacggg tccacggccg acaggtccac
    11821 ggccaacggg tccacggccg acgggtcgac agccaaccgg tcaacttccg acgggccgac
    11881 agccggcggt ccgacagccg gcgggccggg ggccgccggg tcaacggccg gcggtccgac
    11941 agccgccgag ttgccggctg tcgtgccgac ggcgcgcccg tcacggccgt cctcggccgg
    12001 ctccgccgcc ccgcccgcgg cctgcgccgc gcccctcgac cctcccacga ccaacgtccc
    12061 gcccacgccc ctctccccgc ccacgaccaa cgccccgtcc gcggccctct cccctccccc
    12121 ggcctgtgcc cccgcctgcg gcgacgcgat cgggaccgcc gtcgacggga tcgtgcggca
    12181 cctcgtcgac acgatgacgc ccggcgacga ccggaggctg tggccggtgt cgacgctggc
    12241 cggggagagc gatccgtgca gcgtgcagca gggtgcggcc ggtgtcctgg ccgtgctcac
    12301 gcggtacttc gagctgaccg gcgatccccg gcttccggga ccgctcgccg tcgcggggcg
    12361 ctggatcgcg gagcgtaccg aaccgcgttc cgcccgtccc ggcctgcact tcgggacagg
    12421 cggcaccgcc tgggcgctgt acgaggccgg gcgggccgtc ggggaccggg cgctcgtcga
    12481 ccacgccctg gcgctggcgg tggccccgca gcggccgacg ccgagccatg acatcaccca
    12541 cggcacggcg ggcagcggca tggcgagcgt ccacctgtgg cggcgcacgg gcgatccgcg
    12601 gctggccgcg ctggtcggcg aggcggccga ccggctggcc gaagcggccc ggcgggaggc
    12661 gtcgggggtg agctggccgg tgccggcgga ggccgtcgcc gaggaggcgg gcaagcgcta
    12721 cctgggcttc gcccacggct cgtcgggcat cggctgcttc ctcctcgccg ccgcgtccgt
    12781 caccggcagc ccggtccacc gggagctggc cgtggcggcg ggcgagcacc tggtggccca
    12841 cgccgtggac gtgggcggcg cggcccagtg gccggcgcag acgggggacg tgccgacggc
    12901 tccgtactgg tgccacggct cggccggcat cggctcgttc ctggtgcggc tgtggcgggc
    12961 gaccggcgac gaccggttcg gcagcctcgc ccgcgccgcg ggccgggccg tcgtcgagcg
    13021 ggcctcgcgc gccgcgctca cccagtgcca cggcctcgcg ggcaacggcg acttcctcct
    13081 cgacctggcc gaggccaccg gcgacccggc gcaccgcgcg cgggccggcg acctggcccg
    13141 cctcctcctc gccgaacggt ccctgcgcgg cggtcacgtc gtcttcccca acgagtacgg
    13201 ggaggtctcg acgggctgga gcgacggctc cgccggaatc ctggcgttcc tcctgcgggt
    13261 acgccacacc gagccccggc actggatggt ccagctgccg gtctgagcgg cggcgggcac
    13321 gccgccgccg caccccgagg aacggcgcga agaaaacgac acaccacgaa gaagaaggag
    13381 aagaccatgg agaacaagga cctcgaactc ctcgcccagc tgcacgccct tccggagacc
    13441 gacccggtcg gcgtcgacgg cgcgccgttc gccgccacct gcgagtgcgt cggcctgctc
    13501 acgctcctca acaccgtctg catcggtgtg agctgcgcgt agcccgtacc gcctcccccg
    13561 gccggtggct gtcccggggc agccaccggc cggggcgagg ccccggaccc cgcccgcccg
    13621 gccccaccga cgaggacgag accatgccgc tgcaccccgg tgaccacgac tccccccgca
    13681 ccgccgccgc gcggaccgcg ccgccggccg cgtccgtccc ctccgccatc cgcacgcgtg
    13741 gcctggtcaa gagctaccgg gggccggacg gcgcccccgt ccacgcggtg cgcgggctcg
    13801 acctggacgt gcgccagggg gagacgttcg cgttcctcgg cccgaacggc gccgggaagt
    13861 ccacgaccat cgcgatgctc tgcgccctca cccgccccac ctccgggtcc gcgacggtgg
    13921 cgggcgccga cgtgctcacc gagcccgacc tggtacgcgg cagggtcggg ctgctgttcc
    13981 agcacagcgc cctcgacacc gacctgacgg ccgagcagaa cctccgcgtc cacgcacgcc
    14041 tgtacgggct ccgccgcggc gaggcccgcc gccgcacggc cgaggcgctc gacgtcgccg
    14101 gcctgtccga ccggcgccgt gcgcccgtcc gcaccctgtc gggcggcatg cggcgacgcc
    14161 tggagctcgc ccgccagctg ctgcactccc ccggagtgct gttcctcgac gagccgacga
    14221 cgggcctcga cccgcacgcc cgcgtcctcg tccgggacca cctgcggacc ctgcgcgacc
    14281 ggcacggcag cacgctgttc gtcaccaccc actacctgga cgaggcggag cactgcgacc
    14341 gcctcgccat cgtcgaccgg ggccggctgg tcgcgcaggg gaccccgtac gacgtgaagg
    14401 cagcgatcgg agacgaccgg gtggcgctgc gcacgagcga cgacgcgggc gcgcggcgcg
    14461 tcgtcgtccc gctcgccccg cccggccggc ccgtcacggt cgacgcggac ggcctctggc
    14521 tgcgcgtccc ccacggcagc acctggatcc cacggctgtg cgcggcgctc ggctcccacg
    14581 gcatcgacgt ccacgccgcc tccgccaccc cgcccacgct cgacgacgtc ttcttccacc
    14641 acaccggccg cagcatggcc ccggacgaag ggggcggccg atgacgacga cggccacggg
    14701 tggtcgtgtc ggcatcgaca cctgcaccgg caccggcacc ggcaccggcc tccggcggga
    14761 actgcgggcg gtgcacgcgc tggtccaccg cgatctcctc cgcctcgcct gccagcggat
    14821 ccccacggcg ctgatgctgc tccacccggt cctgtacctg ttcatcctgg gcggcggcct
    14881 ggcggcgctg atccccacga cctccctcgg cgtcggctac cggacgtacc tcttcccggg
    14941 catgctgatg atgaccgtgc agactccggc gatcatggtc gggatccggc tgatcaccga
    15001 ccggcagagc ggctacctcc gcgaactcct catggccccc gtgggccgca ccaccctcct
    15061 cctcggcagc tgcgccggcg gcaccctggt ggcgacggtg cagggcgccg tgctcctcct
    15121 cctggcgggc gcggtgggcc tcccgtacga cccggtcctg ctcgtgctgc tcctcggcgg
    15181 cctggtcctc gcgtcgttcg cgatcaccgc gctgtccctg gccctggccg tgggcctgcg
    15241 gagtccggag accttccaca cgctcctcgg cctggtgatg atgccgctgc tcttcctctc
    15301 cggcggcttc ttccccttga cgtccctgcc cggctgggcg caggccctgg cggccgcgaa
    15361 ccccctcgcg tacggcgtgg acgtgctgcg ccgctcgatc gccctccggg cgccggagca
    15421 ggcggcggcc gacggtctcg cctgggccgg gcacccacca cccctcctcc tcgaagcggg
    15481 cctcctcctg gcagcgggcg cggcagccct cacgtgggca gcccgccgct tcggccgccc
    15541 ggagtagccg ccttgagcaa tcgccttgag gagtccgccc gggtcagccg tcccggcccg
    15601 ccagggctcg ggccgtggcc ccgatgcggt cgcggagccc gggcggcggc gccggtgagg
    15661 cgggcggctc cgcacgggga gatccggacg acggcctcgc cagcgccgct cgcacacgaa
    15721 cgcggcgccc ggatccgtca cgtcctcacc cccgagaccc cggacgtccc cgcctgcctc
    15781 gcggacgcgc cccggttcgg cacgacggac tagggctttc cgcagatcgc gaagttcccc
    15841 ttcccttcct tccaggacga catcagggag agcgactcgg tgacgacacg ggagcccctc
    15901 cgcacccgca cgtcgaccgt gccgagcgtc aggtcgggga actcgatggc atggaccgac
    15961 cgccggccgt ccgcgacgac gccgacgtcc ttcacgggga ggggcacgcc gttgcaggtc
    16021 acggactcca cggtctcgtg ctcggcgccg aagaccacgt tccagcccgt ggccatcatg
    16081 gtgaccaagg ggatgatccg gggcttctcc cccaccggtg gcgtgtgggg agccgaggcg
    16141 caggccacca tggtcatgcc gacgggcttc gccgcgccgt ggcagaaccg gccgtccggg
    16201 gtctcccaga cgaagagcgc cccgccggtc gactcggcgg cgaccagcag tccctggggg
    16261 ccgggcgcgt tgcgtccggt ggcggcggtc ctcatctgct cggccgccgc ggcgacggcc
    16321 tcctccacgc tttcggtcgc cgtggccgtt gcggaggcgg tggcggacgg cgtggggctc
    16381 gccgacgacg tcttcggcgt ccgctccggg ctctccgctc ccgcgcagga ggtcacggcc
    16441 agtacggcac aacccaggaa cacgccgacc ctcggtcctc gtagcacttt cccccgcccc
    16501 cggtgcagcc gcctcggcgg cggcggtcct ctagtctgct ccgcatgatc ggaacgttgc
    16561 aatgtgtggt gctggactgc cctgacgtca tggaactcgc gcgtttctac gcttcgctgg
    16621 tcgggggcga ggtcaaccgg cccgatgccc ggtggtcgct cggtgacgac tgggcgacgg
    16681 tgcacgccga cggcgggctc gtgctggcgt tccagcgggt ggcggagtac cgggcgccgc
    16741 gctggccgga tcccggccac cctcagcagt tccacctcga cctgggcgtg gcggatctgg
    16801 atcgggccgg ggcggaggtg ctcgccctgg gggcgacgct tctcgacggc ggtgacggga
    16861 agcggagttg gcgggtgtac gcggatccgg cggggcaccc gttctgcctc gtgcgggact
    16921 gagcgcgccg gtcctcgggg cgtgtgtggg accggcgggc cgtgacgagt tccggacagg
    16981 aatctgctgt tccgcatgag gggcgcggga gcggggagcc atggcggtgt ccgttgtcgg
    17041 ccgattcacc ccgcgaggag ccgccatgtc cgtgccgtat cccccgtcgc ccgacgagcc
    17101 cgtgttcgcc gccgacttcg gctcgccctc gcaatgggtc gccgggcgta cctgggccta
    17161 tccggacggc gggccggtca atccgctcga caacaaactc gaccacctcg tggacgatcc
    17221 cgcctactgc cgctccgggg tcttccgggc gacccgacgg cccgacggcc tgtgggacag
    17281 cgggctgctg acgacggagg gcagcgagga ggggttcgag gtccgggcgg gggacgtgct
    17341 ggaggcccgg gtgcggctgc cgtcggagac gggggcctgg ccggcgatct ggacctggcg
    17401 cgacggcggg caggaggtcg acgtcttcga gtaccacccg gacaaccccg atctgctgga
    17461 gctctccaac cgcgtgcggg gcacccatca ctaccaccgt tcgcccgacg tccggcccgg
    17521 ggagtgggtg gagctgcgga ccgagttcgg ggcccggtcc gtggtgtggt gggtgaacgg
    17581 caccgcggtc ttcgccgacg gccggggcgt cgggcgctcc tggcacgcct gcctgatcgt
    17641 caacctctcc gtctgcgccg gccgatacca ccccgcgccc gatcccggga ccaccgagat
    17701 gtccttcgag gtggcggatc tccgggtgct ccggagccgc tggtgaggtg ggcgtcgccc
    17761 cgggcccgcc cctcaggcgt ggtacccgcc gtcaggccct ggcgcctgcc caccagccct
    17821 ggcgcccgcc cgtcaggccc tggccatgcc ccgggcctcg gcgcgccgcg tcgcctcgtc
    17881 gccggtcagg agggcgaggg cctcctgggc gtgggccggg gcggtggtgg tggcgaggac
    17941 ggcggcggtg aagagggagg tgatggccgt gtcgccgggg agggggccga ggacggtgac
    18001 tccggggagg tccatcagtt cgctgtgctg ctggaaggcc aggtcggcgc ggccggaggc
    18061 gaggagggtg ccggcgggga cgccgggtgg ggcctggacc aggcggtcgg tgagcgtgtc
    18121 ggccagggcg aggcggtgga ggaggtcaag gagggccgtg ccgctggggc cggtggagta
    18181 ggcgatggcg gtcgccgacg tgagagcggt gcggaggtcg ccgaccgtgt cgaggggtag
    18241 ggccggggcc tgcgccggta cggcggcgac gacctgggag cgccacaggg ggcgggccgt
    18301 tccgggggcc aggtgtccgg cctcctccaa cgccgtcacc gcgtcggcgg cgaggacgag
    18361 gaggtccgcc tcggtgccct cgcgcacccg gcgggcgatc tccacgccgc cggcggactc
    18421 gaagcgtatc cgcgtcccgt cggcgaggcg gaggtgtgcg cagaggtcgg cgaggatcgg
    18481 gcgggtcgcc atcgaggaca gtcctacgag ttctcggtgc atgtcgaggc ctcacgtggt
    18541 cgtgtcggga tcgggagagg ggagacgaga gaggggagcg cggcaggcgg ctcggggcgg
    18601 gtccgcggga gtctgcgaga ctggcggcgt gagcacgacc cggagcaccg cggcaggcaa
    18661 agtactggag gtcctcgcgg tcttcgaccg tgagcacccg gcgcagacac tatccgagat
    18721 cgcccagcgg accggcctgg cgctgagcac cgcgcaccgg gtggtcatgg agctggcggc
    18781 gtggggggcg ctggagcggg gcgaggacgg ggcgtggcac gtggggctgc ggctgtggga
    18841 gatcgcctcg ggctgtcccc ggacgcagat cctgcgggac gtggcgctgc cgttcatgca
    18901 ggacctgtac gaggtgacgc acgagaacgt gcagctcgcg gtgcgggagg gcacggagct
    18961 ggtgttcgtg gagcggatcg ccgggcaccg gtcggtggag ctgctcaccg gggtcgggac
    19021 ccgcttcccg gtgggggcga cggggatggg gcgggtgctt ctcgcgcacg cgccggggga
    19081 catccaggag gaggtcctgg gggcgccgca gcgggcgtgg acgccgcaca cggtcaccga
    19141 tccgaggaca ttgcgggcgc agttggaccg gatccgccgg gagcaggtct tcgtcagcga
    19201 ccggcagttg tcggagagca cggtggcggt ggcggcgccg gtgcggatcg ggcggtcggg
    19261 gccggtgagc gcggcgctgg ggatcgtggt cacggcggag ggcgcggacc gggcgcatcg
    19321 gttgcgcgag ccgctgctgc gggccgcgta cgggatctcc gacgaactcg gcaggcggac
    19381 gcggacgacg gagtgacttc cgggccggct tccgcctgac ggaaacgccg cagaccgggg
    19441 ggtgggcagg ctggcagcgt tcgggccgtt ccgaaccgtt cggatcgctc acagctgctt
    19501 gggagatgcc atggccgacg cccccgtcga ctccgtcgtc tcggttccgg tcgcggtggt
    19561 cggcgcgggg cccgcgggcc tcatgctggc ccatctgctc ggccgtgccg gggtcgaggc
    19621 ggtcgccgtc gacacccgta cgcgtcacgg gatcgagacg acgcagcggg ccgggatcct
    19681 ggaggccgac gtcgcccggg acctggtcga caccggggtc tcggaccgga tcctgcggga
    19741 cgggtacgag cacgagggca tcgaggtgcg gtcgggcgga cggccgtacc ggatcgactt
    19801 caagaagctc gtcggcgcgt ccacctggct ctatccgcag accgacgtct tcgtcgacct
    19861 ggcggacgcc cgcgaacgcg acggcggcac cgtccacttc gggatccggg acaccgaggt
    19921 cctcgacgtc accaccgacg ccccgcgggt gcggtacacc gcgcccgacg ggacccggca
    19981 cgagatccgg gcgcggtacg tggtcggcgc cgacggctcg cggagcatgt gccgcgacct
    20041 ggtgccggag ggccggcgga cgcggtacgg caaggagtac cccttcgcct ggttcggcat
    20101 cctcgccgag gcaccgagga gcgcgccgga gctggtctac gcccgttccg agcacggttt
    20161 cgcgctgatc agccagcgca ccgaggccgt gcagcgcatg tacttccagt gctcccccga
    20221 cgagtccgcc gacgcctggt ccgacgaccg gatctgggag acgctccagg cgcgggtggc
    20281 cggcgaggac ggcttccggc tgaaggaggg gccgatcacc gagaagacgg tgctgcggtt
    20341 ccgttccttc gtgcaggagc cgatgcgctg gggttcgctg ctgctggccg gcgacgccgc
    20401 gcacacggtg ccgcccaccg gggcccgcgg gctcaacctg gcgctgcacg acgtgaaggt
    20461 cctcgccgag gtgctgctga aggcgctcgg cggcgccggc gagacggccc tggaggagta
    20521 cgagccccgg gcgctgcggc ggatctggcg ggcgcagaac ttctcgtact ggatgacccg
    20581 gctgctccac accgcgcccg gggcctcggc gttcgacctg cggcgtcagc tcggcgagct
    20641 ggagaacgtg gtggggacgc gcgccggacg gacgtacctg gccgagcagt acaccggctg
    20701 gcccacccgc gaccactgac caccgcaccg gacgaccccg aggcctcccc atgatcatcg
    20761 actgtcacgg ccacttcacc accgccccgc cgaagctcgc cgcctggcgc gagcggcaga
    20821 tcgccgccgc cgagggccgc ggccccctcc cggaccccga cgagctggtc atcaccgacg
    20881 acgagctgcg cgccgcggtc gagggcaacc agctgcgcct gatggacgaa cgcggcagcg
    20941 acctcacggt gttctcgccg cgggccagtt tcatggccca tcacatcggc gacttcgccg
    21001 tctcctcggt gtgggcgcgg atctgcaacg acctggtgca ccgcgtcgcc gccctctacc
    21061 ccgaccggtt cgcgacgggc gcgatgctgc cgcagtcccc gggcgtcgac cccgcgacct
    21121 gcctgcccga actgacgcgt gccgtcgagg agttgggcgc cgtcacggtg aacctcaacc
    21181 ccgacccgtc gggcggccgt tggagcgcgc cgccgctgac cgaccgcagc tggtacccgc
    21241 tgtacgaggc catgacggcg tacgacatcc cggcgatgat ccacgtcagc acctcctgca
    21301 acccggcctt ccacaccacc ggcgcgcact atctgaacgc cgacaccacc gccttcatgc
    21361 agctggtgca gggcgacctg ttcgccgact tccccacgct gcggttcgtg atcccgcacg
    21421 gcggcggcgc cgtcccgtac cactggggcc gcttccgcgg cctcgcgatg gccctcggca
    21481 ggccggatcc ggaggcgctg ctcgacaacg tcttcttcga cacctgcgtc taccaccagg
    21541 cgggcgtcga cctgctcacg cgggtgatcc ccagccggtc cgtcctgttc gccagcgaga
    21601 tgatcggcgc cgtccgcgac gtcgacccgc gcacgggcca tcacttcgac gacacgaagc
    21661 ggtacgtcga cgccaccccg cacctgtcgg acggggagcg tgccgccgtg tactccggca
    21721 acgccctgcg cgtctacccc cgactcgccg cccgcctcgc cgcggccggc cgctgacccc
    21781 aggagaagca cccatggaac acaccgagat cggcgtcgtc cgcacgcacg tcgaacgggc
    21841 cgccccggag gccgtcgccg aactgtcgaa gtacggcgtc gccacgatcc acgaggccat
    21901 gggccgcgtc gggctgatgc ggccctacct gcgcccggtc tacccgaagg cccggatgtg
    21961 cggcacggcc gtgaccgtgc tcctccagcc cggcgacaac tggatgctgc acgtggccgc
    22021 cgagcagatc cgggacggcg acgtcgtcgt cgcggcctgc acgacggaga gcgaggacgg
    22081 cttcttcggc gagctgctcg ccacctcctt ccgcgcccgg ggctgccggg gcctcgtcat
    22141 cgacggcggg gtgcgggacg tcgccgacct ggaggggatg gacttccccg tcttctcccg
    22201 cgcggtcaac gccaagggca cggtcaaggc cacgctcggc tcggtcaacg tgcccgtggt
    22261 ctgcggcaac gccctggtcc ggcccggtga cgtggtcgtc gcggacgccg acggcgtcgt
    22321 cgtcgtgccg cgcgagcggg ccgccggggt ggccgccgcg gcggcggccc gggaggccgc
    22381 tgaggagggc aagcgggcgc agttccgggc cgggaagctc ggcctggacc tgtacgggat
    22441 gcgcggcccg ctggcctcgc tgggactgcg gtacgaggac ggacgatgac ggccttcgag
    22501 aagacgccgg gctggctgga ctggtacgcc ggtccgagcc ggccggagtt ccggctcccc
    22561 gagggcgccg tcgacgcgca ctgccacgtc ttcgggcccg gcgaggagtt cccgtacgcg
    22621 cccgagcgca agtacacgcc ctgcgacgcg tccaaggagc agctcttcgc gctccgcgac
    22681 cacctcggct tcgcccgcaa cgtcgtcgtg caggccacct gtcacggcgc cgacaactcc
    22741 gccatggtcg acgccctgcg ggcctccggc gggccggccc ggggcgtggc gacgctgcgg
    22801 cccgacgtca ccgacgccga ggtgcgggag ctgcacgagg ccggcgtccg gggggtgcgg
    22861 ttcaatttcg tccggcggct ggtcgacgcg gcgccggagc aggacctcct ggacatcgcc
    22921 gagaagatcg ctccgtacgg ctggcacgtc gtcgtctact tcgaggcggc cgacctcgcc
    22981 cgcctgcggg acttcctcct cgccctgccc gtgccgctgg tcgtcgacca catgggccgg
    23041 ccggacgtcg gcaaggaccc ggacgggccg gagttcgggg ccttcctgga cttcctgcgc
    23101 gcccgcgccg acatctggtg caaggtgacg tgccccgagc ggctcagcgc gagcggtccg
    23161 ccggccctgg acggcgagcg gaacccgtac cgggacgtcg tgcccttcgc ccggcgcgtg
    23221 gtcgaggagt tccccgaccg ggtcctgtgg ggcaccgact ggccgcaccc caacctcacc
    23281 ggccacatgc ccgacgacgg gctgct
//
