LOCUS       NZ_JABBGE010000006     21056 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. R302 contig6, whole genome shotgun sequence.
ACCESSION   NZ_JABBGE010000006
VERSION     NZ_JABBGE010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. R302
  ORGANISM  Streptomyces sp. R302
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 596581)
  AUTHORS   Dahal,R.H.
  TITLE     Streptomyces sp. R302 sp. nov., isolated from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 596581)
  AUTHORS   Dahal,R.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) Life Science, Kyonggi University, Kyonggi
            University, Suwon, Gyeonggi-Do 16227, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2020
            Assembly Method                   :: SPAdes v. APR-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012927245.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 03:52:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,357
            CDSs (total)                      :: 7,271
            Genes (coding)                    :: 7,075
            CDSs (with protein)               :: 7,075
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 84 of 196
            Pseudo Genes (incomplete)         :: 164 of 196
            Pseudo Genes (internal stop)      :: 20 of 196
            Pseudo Genes (multiple problems)  :: 67 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 20636
            Orig. end                         :: 41692
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBGE010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(166..1143)
                     /locus_tag="HHL19_RS19185"
                     /old_locus_tag="HHL19_19190"
     CDS             complement(166..1143)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890991.1"
                     /locus_tag="HHL19_RS19185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19190"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_169091262.1"
                     /transl_table=11
                     /translation="MKRASKPAKPAKPAKPASRPRTKAKDESATVLYDVPGPRARRRNL
                     LWTLLFLAALAAVVWWVIAGLDAKNQLEAEKWEPFFTDGRVWETYLLPALKNTVIAAAL
                     AMVLALPLGAFLGIARLSDHRAVRGVAGTVVEFFRAIPVLILMLFANAAYAEFTDISPE
                     TRPLYAVVTGLVLYNASVLAEVVRAGILALPAGQTDAAKAIGMRKGQTMAYVLLPQSVT
                     AMLPALVSQLVVIVKDTALGGAMLGFAELLASVRPLSANYGANTIACFTVVAVLFVLLN
                     VALTTFASWLERRLRRGKRTTGAVVTAEAVEDLATPGEPTGPKP"
     gene            complement(1140..1805)
                     /locus_tag="HHL19_RS19190"
                     /old_locus_tag="HHL19_19195"
     CDS             complement(1140..1805)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_process="GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038135.1"
                     /locus_tag="HHL19_RS19190"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the opines
                     (in Agrobacterium) octopine and nopaline, etc.; The
                     N-terminal region of this protein, as described by
                     TIGR01726, is a three transmembrane segment that identifies
                     a subfamily of ABC transporter permease subunits, which
                     specificities that include histidine, arginine, glutamine,
                     glutamate, L-cystine (sic), the opines (in Agrobacterium)
                     octopine and nopaline, etc; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HHL19_19195"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_169091264.1"
                     /transl_table=11
                     /translation="MFDFLEGYDLLGAFWVTVQLTFWSALGSLVWGTLLAAMRVGPVPL
                     MRGFGTAYVTIVRNIPLTVIIVFTSLGLFQTLGISLGADRFTTINFRLAVLGLTAYTSA
                     FVCEALRSGINTVPLGQVEAARAIGLSFPQILRIIVLPQAFRSVVGPLTNVLIALTKNT
                     TVAAAIGVAEAALLMREMIENEAQLILISAIFAFGFICLTLPTGLLLGRLAKKVAVKR"
     gene            complement(1816..2658)
                     /locus_tag="HHL19_RS19195"
                     /old_locus_tag="HHL19_19200"
     CDS             complement(1816..2658)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241866.1"
                     /locus_tag="HHL19_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19200"
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_169091266.1"
                     /transl_table=11
                     /translation="MNPLRTTRTLVASATAVVLALGTASVAQGAVPADHDDDDQITIGI
                     KFDQPGIGLKTPDGTYTGFDVDVATYIAKQLGHEPDQIVWKEAKSADRETMLQRGDVDF
                     IAASYSINDERAEKVDFAGPYLLAHQDVLIRADDDSIKQPSDLNDKRLCSVTGSTSAQN
                     VKEEIAPDAQLQEYGGYSECLTGLENGVIDALTTDDSILAGYAAQEGFKGKFKLGGFEL
                     SNENYGIGVQKGSDLKGEINTALEKMVEDGSWDEAVEKNFGPANYQNEPAPKIGVIVE"
     gene            complement(2678..3466)
                     /locus_tag="HHL19_RS19200"
                     /old_locus_tag="HHL19_19205"
     CDS             complement(2678..3466)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055346.1"
                     /locus_tag="HHL19_RS19200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19205"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_169091268.1"
                     /transl_table=11
                     /translation="MPVPEVPVTEHDPVAGDGDALVVLRGVDKYFGTLHVLQSIDLTIR
                     RGEVVVVIGPSGSGKSTLCRAINRLETIDSGEIRVDGRPLPAEGRELARLRADVGMVFQ
                     SFNLFAHKTVLDNVTLGQIKVRKKDRKAAEERARSLLDRVGVAAQAAKYPAQLSGGQQQ
                     RVAIARALAMDPKVMLFDEPTSALDPEMINEVLEVMRQLARDGMTMVVVTHEMGFARSA
                     ANRVVFMSDGRIVEEATPEEFFGNPRSARARDFLSKILHH"
     gene            3687..4145
                     /locus_tag="HHL19_RS19205"
                     /old_locus_tag="HHL19_19210"
     CDS             3687..4145
                     /GO_function="GO:0030551 - cyclic nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241869.1"
                     /locus_tag="HHL19_RS19205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19210"
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="WP_169091270.1"
                     /transl_table=11
                     /translation="MRSAAPKVGSLPAEHRERLMAFAEDVYFDSGDRLFEEQRHADRFW
                     IVKTGAVNLDAKVPGRGAPVIETLRHGELVGLSWLFPPYLCQSGAEAMTPVRAYEFDAT
                     AVRAMCHTDVEFGSAVYYWVGSILAHRLQVTRVRLLDLYAPHGSGIMA"
     misc_feature    complement(3711..3726)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            4756..6117
                     /locus_tag="HHL19_RS19210"
                     /old_locus_tag="HHL19_19215"
     CDS             4756..6117
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526214.1"
                     /locus_tag="HHL19_RS19210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19215"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_169091272.1"
                     /transl_table=11
                     /translation="MTAAPSAREALALVTDDFTELPSAAGPGGDGPIDWPGYGRARAAA
                     AARSGEDESVVCGTGTVGGTRTVLVSFEFGYLGGSIGEGTGDRVAAAHAHARAHRLPVT
                     VLLATGGSRMHEGMRALVQLQRLAGESALTRAAGLPQLAVLRDPTTGGGWATLGAGSDV
                     VLALPGAQVGFAGSRVRPGDADPAAYTAESQLAHGHVDAVVPAAELREVLGRWLSLLTR
                     PAEGPVPPPYALGATDPAASGRDAVARARHPERPRADRYLAEVFTERAELSGDRVGGTD
                     PGTRCGFGRLPDGRTAAYAAQCGTATRPAGFRTAARLVRLAGRLGIPVLTLIDTPGAAN
                     DAEAERAGAGPAIAELFGAVAEAPVPVTALLVGEGGSGGALALAAPGNTWATPDSYFSV
                     IAPELATAILKRAPEDADATADDLRLRPDDLVALGVVRGVVGARPAPDRGGADG"
     gene            complement(6191..6514)
                     /locus_tag="HHL19_RS19215"
                     /old_locus_tag="HHL19_19220"
     CDS             complement(6191..6514)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022684.4"
                     /locus_tag="HHL19_RS19215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19220"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_169091274.1"
                     /transl_table=11
                     /translation="MDEARLSAHERRVLAEIEADLSADDRLASRMGEHRQVPRLPRIAG
                     RGGVGAVALGALTLTLLVLAVATSTPALIWAFAAAWVVTLILLLRMVVRWTRRRAGGGR
                     HDD"
     gene            6772..7698
                     /locus_tag="HHL19_RS19220"
                     /old_locus_tag="HHL19_19225"
     CDS             6772..7698
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884116.1"
                     /locus_tag="HHL19_RS19220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19225"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_169091276.1"
                     /transl_table=11
                     /translation="MATGRVVDAPPLPSPAREATSTSAATRRRALGGLPEPENPLSSST
                     DDARTLSAAMFVRLRELDEGSPEHAYVRNTLVELNLSLVKFGARRFRGRPEPVEDIVQV
                     GTIGLIKAIDRFDPDRGVEFSAFALPTIVGEMKRFFRDTGWAVRVPRRLQELRIDLAKA
                     SDALEQRDGHRPDRAELAERLHLTPEEVAEGELAANGYTAHSLDAPVGDAESQAPQGTA
                     GRRTAVDEPAYELIDDLSSLRPLLDRLCPRDRLILSLRFGEELTQAEIGRRIGLSQMHV
                     SRLLARILGELRDGLLDDDATEDATAC"
     gene            complement(7646..8140)
                     /locus_tag="HHL19_RS19225"
                     /old_locus_tag="HHL19_19230"
     CDS             complement(7646..8140)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884118.1"
                     /locus_tag="HHL19_RS19225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19230"
                     /product="ATP-binding protein"
                     /protein_id="WP_169091278.1"
                     /transl_table=11
                     /translation="MRERESDETRGGGTPVAQTRRLLLRGSVGAVSRCRDFTAEALAEW
                     GWTPAESALARERVEDVLLLVSEVVTNACLHGGGPEEFVLRHADGLLRVEVADRSPDHP
                     RRLAPRSPSLPGGHGLMVLDRLATDWGSSDRGPGAAGKVVWLEVSRPSRPPWRRRPADR
                     P"
     gene            complement(<8298..8684)
                     /locus_tag="HHL19_RS19230"
                     /old_locus_tag="HHL19_19235"
                     /pseudo=""
     CDS             complement(<8298..8684)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016910679.1"
                     /locus_tag="HHL19_RS19230"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19235"
                     /product="STAS domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDGGEGQEGAPGSGPPTGRPGRLRVDVRFDRGGETVVVAPLGELD
                     HDTAEPLGTALEKHADAARLVVDCAGLDFCDSTGLNLLLRARARALEAGARLDLAGLRP
                     PVDRMFEITGALHVFRVYADAHEAL"
     misc_feature    complement(8684..8700)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            complement(8763..9971)
                     /locus_tag="HHL19_RS19235"
                     /old_locus_tag="HHL19_19240"
     CDS             complement(8763..9971)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978298.1"
                     /locus_tag="HHL19_RS19235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19240"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_169091282.1"
                     /transl_table=11
                     /translation="MPGTHSTATHTTATLTPTPYTDASLDALRHSGDELADAVVATLFE
                     RGEVGLFNSLMRYVSVSGQELPAGLPDVAREYLEATAVPPAWVDWNEMEKARLFFTDNN
                     VHINTALSFASMPACYVVPRVARLLSATHGLHYPSKRMAETGQFTTYLMRPDAFEAGGR
                     FVPAAQKVRLLHASIRHHLIRADRWDTAADGVPICQEDMIGGQMFFSMLVLDSLHRLGV
                     HMSTEGAEAYSYAWRVVGAILGVDQTVVPKTLDEARAFLDLYLLRHMGPSEEGVVLTRQ
                     LIDLYEDVVPGTFFDPVVSALIRHLVGDTVGDWLDVPRSRWDTAVKALPPLLGVLESVE
                     DASPFAAWALDRIGHLTSVFELSTLTRGRVMHYAVPEHLRKEYGVDTGVARHHRWTPPP
                     STV"
     gene            complement(10001..11056)
                     /locus_tag="HHL19_RS19240"
                     /old_locus_tag="HHL19_19245"
     CDS             complement(10001..11056)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330751.1"
                     /locus_tag="HHL19_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19245"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_169091284.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-39, bitscore:
                     130.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDVWVPEEFKARTDAVLAGFLDDEATALLAVDDALDPLAEALRT
                     TARHGKRLRAAFCYWGWRAAGQPDSDALMRAAAAMELVHAAAVVHDDLIDDSPLRHGRP
                     TAHHHFAALPHLGRRPRAAARALALLLGDHLMALAGRLYAESGLPAAYLSRGRPLWAAL
                     ARELVAGEALEILHTGGPPDTGTSLKVICYKTAKYTVEHPLLLGGLLAGAPAALREGFS
                     RYGLPLGEAFQLRDDLLGLFGDPARTGKAPLDDLRAARPTVLLAETWNAADPAQRELLR
                     RTLAGDRRPDDGELREVRALMAGLGAPARVERMITGRVEEAVRTLDELDLPAAAHRALT
                     DLAHRAAVRHH"
     gene            complement(11049..11405)
                     /locus_tag="HHL19_RS19245"
                     /old_locus_tag="HHL19_19250"
     CDS             complement(11049..11405)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978296.1"
                     /locus_tag="HHL19_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19250"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_240981729.1"
                     /transl_table=11
                     /translation="MTHPTPPGERPDEKALLMAAGLADLVVETIGTAAGSLRSLLGRAD
                     SADLAQDAAADLRARGRLALDRLAADRDGPRSVPHMELLAREAAARRAAAQAPAADPDT
                     RQARQVRTEAAPDA"
     misc_feature    12019..12028
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    12055..12068
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.58"
                     /tool="antismash"
     gene            complement(12195..13850)
                     /locus_tag="HHL19_RS19250"
                     /old_locus_tag="HHL19_19255"
     CDS             complement(12195..13850)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241882.1"
                     /locus_tag="HHL19_RS19250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19255"
                     /product="glycosyl hydrolase family 8"
                     /protein_id="WP_169091286.1"
                     /transl_table=11
                     /translation="MRRRSAIPLGLAALLALPALTVLPASEAEAVDALVSAGKPATSSS
                     VEGSGFAPGLAVDGSRATRWASLEGVDPQWIRIDLGANHTLSRIKLDWEAAYAKTYRLQ
                     TSADGSTWTDVYATTSGDGAVDDLAVSGTGRYVRMYGTGRGTPYGYSLYEFEVYGSPTG
                     GGGGTGPGVPFGSHLKPYAAGMLKPSGTQSGIDQKVVDYYNRWKSAFVRQNCGNGWYQV
                     ISPDADHPYVAEAQGYGMVIAATMAGADPDAKKIFDGLVKWKLDHPSSINPDLLAAEQD
                     VDCRSVNGGDGATDGDMDVAYGLLLADKQWGSAGTYDYKALALKHIAAIKKDELNPTTK
                     LLKLGDWSSSGDQYYYISRTSDWMVDHFRAFRAATGDTTWDAARTAHQTQIANLQSGYA
                     PGTGLLPDFVVNTNTSPKPAPGEVLEDPNDGQYWWNACRTPWRIADDAVTSGDAKSLAA
                     ARKLNGWIKSKTGGDPNKIAMGYKLNGTQISAGSEAAFFAPFAVAAMTDSGSQAWLDAL
                     WNKMTATPIDTGSYFSASIQLQVMITVSGNHWVP"
     misc_feature    13890..13905
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.95"
                     /tool="antismash"
     gene            complement(13982..14746)
                     /locus_tag="HHL19_RS19255"
                     /old_locus_tag="HHL19_19260"
     CDS             complement(13982..14746)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (25-124). E-value:
                     6.6e-19. Score: 60.4. Matches aSDomain:
                     nrpspksdomains_HHL19_RS19255_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038514.1"
                     /locus_tag="HHL19_RS19255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19260"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_169091288.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-20, bitscore:
                     69.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.3e-14, bitscore: 48.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRELFLADRQAHLRWIDLPGEGPVRVFLHGLGCTAASDFAHIATH
                     PALGGGRALLVDLLGHGLSDRPGDFDYRPEGQAAAVAALLDHLDLRGVELVGHSMGGAV
                     AIHLAAARPGRVARLVVAEPNLYGGGGAFSGPVARQPEEAFVRSGYAKLLALAERADYA
                     ARLRLADARAVHRCAVALVEGGDPEAGEVLRALTLPRAFLVGEKSLPDRAAEQAAEMGV
                     PVLEVPAAGHNLMLDNPDGFASALARALTLPG"
     aSDomain        complement(14375..14671)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HHL19_RS19255_Abhydrolase_1.1"
                     /evalue="6.60E-19"
                     /label="HHL19_RS19255_Abhydrolase_1.1"
                     /locus_tag="HHL19_RS19255"
                     /protein_end="124"
                     /protein_start="25"
                     /score="60.4"
                     /tool="antismash"
                     /translation="VFLHGLGCTAASDFAHIATHPALGGGRALLVDLLGHGLSDRPGDF
                     DYRPEGQAAAVAALLDHLDLRGVELVGHSMGGAVAIHLAAARPGRVARLVVAEP"
     CDS_motif       complement(14417..14464)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS19255_0002"
                     /evalue="1.00E-04"
                     /label="NRPS-te1"
                     /locus_tag="HHL19_RS19255"
                     /protein_end="110"
                     /protein_start="94"
                     /score="14.9"
                     /tool="antismash"
                     /translation="LVGHSMGGAVAIHLAA"
     CDS_motif       complement(14639..14686)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HHL19_RS19255_0001"
                     /evalue="2.10E+01"
                     /label="NRPS-te1"
                     /locus_tag="HHL19_RS19255"
                     /protein_end="36"
                     /protein_start="20"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="EGPVRVFLHGLGCTAA"
     gene            14919..15554
                     /locus_tag="HHL19_RS19260"
                     /old_locus_tag="HHL19_19265"
     CDS             14919..15554
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018529334.1"
                     /locus_tag="HHL19_RS19260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19265"
                     /product="LysE family translocator"
                     /protein_id="WP_169091290.1"
                     /transl_table=11
                     /translation="MASSTAFWSFALVVGLLTLTPGLDTALILRTAALGRRTRAWGVVL
                     GIQTGTLIWGALTSLGVTALLTASHLAYEILRWAGAAYLLWMAGRMIAETFRRRGADAS
                     AEVEVGGADTLTGGWHQGTLTNLLNPKVGVFYVAVLPQFIPAEAPHFAMGLALTSVHVV
                     LGVVWSTVLIASASALGTWLRGARARRVLDRVTGTVIGAFAVRLAVSD"
     gene            complement(15604..17103)
                     /locus_tag="HHL19_RS19265"
                     /old_locus_tag="HHL19_19270"
     CDS             complement(15604..17103)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134163.1"
                     /locus_tag="HHL19_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19270"
                     /product="hypothetical protein"
                     /protein_id="WP_169091292.1"
                     /transl_table=11
                     /translation="MYALLHGLAANPALPSALLDRLIALADDELAGALARRTDLDRGRA
                     LALARRVGDAAAVSLAYEGRLAAADVDPAEWPEAALALLDRGAAPAAWARAFAGDPDPG
                     RRERLAACPGLPPDVTERLARDPVPSVVAESAWLGPADMAARLAAHPHLSVRRAVAEND
                     TTPPAVLASLLTGEGLPPARRCRVCAVEGETTGPVLPPGERCGGDHESAVVHLRESLLR
                     NPATPPQAAARFADDPHPLLRWAVAGRADLSRDACVRLAADPLPLVRAALAENPALDGD
                     LVRSLADDPDPEIRRAVARHPRVPLDVLVPLARTTALGTVLLPRIATASADETGELVAS
                     AEPAARRLVALRRDLPTGARDRLADDPDAKVAAAVAPHPGLSEARLRAMVVRHGRQVMA
                     GVAANPDTPAALLEELARHQPPVRGALREIDRHRAVTPPALLVCLADARARPFAAGHPA
                     LPPAVLRGLLADADADEAVREAAAAHPSLPPTEMARLLPEP"
     misc_feature    complement(17212..17230)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    complement(17265..17282)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(17318..17704)
                     /locus_tag="HHL19_RS19270"
                     /old_locus_tag="HHL19_19275"
     CDS             complement(17318..17704)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308247.1"
                     /locus_tag="HHL19_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19275"
                     /product="VOC family protein"
                     /protein_id="WP_169091294.1"
                     /transl_table=11
                     /translation="MRINITSVFVDDQETALRFYTDVLGFATKHDVPLGEDRWITVVSP
                     EDPEGTELLLEPSGHPAVPPYKAALVADGIPATSFAVDDVHAEHTRLTALGVRFTQPPV
                     DMGPVTTAILDDTCGNLIQLTQYK"
     gene            complement(17701..17994)
                     /locus_tag="HHL19_RS19275"
                     /old_locus_tag="HHL19_19280"
     CDS             complement(17701..17994)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003968613.1"
                     /locus_tag="HHL19_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19280"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_169091296.1"
                     /transl_table=11
                     /translation="MEEDLFKALADPTRRVILDELTERNGQSLFEICARLATRHGLAIS
                     RQAVSQHLAVLETAGLVTPRREGRYKFHDLDPRPLEHIVTRWLTPAPPEDTP"
     misc_feature    complement(17975..17989)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.43"
                     /tool="antismash"
     gene            18124..20517
                     /locus_tag="HHL19_RS19280"
                     /old_locus_tag="HHL19_19285"
     CDS             18124..20517
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014150925.1"
                     /locus_tag="HHL19_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_19285"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_169091298.1"
                     /transl_table=11
                     /translation="MSTAKRSGAATPPTAHVADSHELIRVVGARENNLKDVSVEIPKRR
                     LTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFVQGFMPTLARPDVDVLDGLTTAII
                     VDQQRMGADPRSTVGTATDANAMLRILFSRLGTPHIGSSRAFSFNVPSVSGAGSVTVER
                     GGRTVKEKASFQITGGMCPRCEGRGRVSDIDLAELYDDTKSLDEGALTIPGYTADSWYG
                     RTYRLSGLLDPAKPIRKYNKRELETLLYKEATRVKVEGVNVTYEGLIPKLQKSFLAKDV
                     ESLQPHIRAFVERATTTQVCPECDGTRLNEGARSSKIKGISIADACAMQISDLAVWVGE
                     LDDSSVAPLLESLRRTLDSFVEIGLGYLALDRPAGTLSGGEAQRVKMIRHLGSSLTDVT
                     YVFDEPTAGLHPHDIQRMNELLLRLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGTGG
                     GTISYEGTLEGLRGSGTVTGRHLDDRASVKDAVRTPTGALAIRGATANNLRKVDVDLPL
                     GVLAVVTGVAGSGKSSLVHGSIPADAGVISVDQTPIRGSRRSNPATYTGVLDPIRKAFA
                     KANGVKPALFSANSEGACPTCNGAGVTYTDLAMMAGVATTCEECEGRRFMASVLEYKLG
                     GRDISEVLAMPVSEAEEYFGAGEARTPAAHRILERLVDVGLGYLTLGQPLTTLSGGERQ
                     RLKLATHMGDKGGVYVLDEPTTGLHLADVEQLLALLDRLVDSGKSVIVVEHHQAVMAHA
                     DWIVDLGPGAGHDGGQIVFEGTPADLVAARSTLTGEHLAQYVGA"
ORIGIN
        1 tgctcccgtg acgtcggttc gtcacggatc gggaggcggg gtcagcaggc gtcgcgggcc
       61 gcgtcctcga actcctcccg ggtcgactcg cggtccaggg tcaggacgct gtgccgtgtc
      121 gggcgcggtg tcgcacgccc gggtggcggc gggcccacgg tgtggtcacg gcttggggcc
      181 ggtgggttct ccgggtgtgg cgaggtcctc gacggcttcg gcggtgacga cggctccggt
      241 ggtgcgcttg cctcggcgca ggcggcgttc gagccaggag gcgaaggtgg tgagggcgac
      301 gttgaggagg acgaagagga cggcgacgac ggtgaagcag gcgatggtgt tggcgccgta
      361 gttggcgctc agggggcgga cggaggcgag gagttcggcg aagccgagca tggcgccgcc
      421 gagggcggtg tccttgacga tgacgacgag ctggctgacg agggcgggca gcatggcggt
      481 gacggactgg ggcaggagga cgtacgccat ggtctggccc ttgcgcatgc cgatggcctt
      541 ggccgcgtcg gtctggccgg cggggagggc gaggatgccg gcgcggacga cttcggcgag
      601 gacggaggcg ttgtagagga cgagtccggt gacgaccgcg tacagggggc gggtctcggg
      661 gctgatgtcg gtgaactcgg cgtaggcggc gttggcgaag agcatcagga tgaggacggg
      721 gatcgcgcgg aagaactcga cgacggtgcc ggcgacgccg cggacggcgc ggtggtcgga
      781 gaggcgggcg atgccgagga aggcgccgag cggcagggcg aggaccatgg cgagggcggc
      841 ggcgatgacg gtgttcttca gggcgggcag cagatacgtc tcccagacgc ggccgtcggt
      901 gaagaacggc tcccatttct ccgcctccag ctggttcttg gcgtcgagtc cggcgatcac
      961 ccaccagacg acggcggcga gggcggcgag gaagagcagc gtccagagga ggttgcggcg
     1021 gcgggcgcgg gggccgggga cgtcgtagag gacggtggcg gattcgtcct tcgccttcgt
     1081 ccggggcctg gaggcgggct tggcgggctt ggcgggcttg gcgggcttgg aggcgcgctt
     1141 caccgtttga ccgcgacttt cttcgcgagc cggccgagga ggaggccggt gggcagggtg
     1201 aggcagatga agccgaaggc gaagatcgcc gagatgagga tcagctgggc ctcgttctcg
     1261 atcatctccc gcatgagcag ggcggcttcg gcgacgccga tcgcggcggc gacggtggtg
     1321 ttcttggtga gcgcgatgag gacgttggtg agcgggccga cgaccgaccg gaacgcctgc
     1381 ggaagcacga tgatccggag gatctggggg aagctgaggc cgatcgcccg ggcggcctcg
     1441 acctggccga gggggacggt gttgatgccg gagcgcagcg cctcgcagac gaaggcgctg
     1501 gtgtaggcgg tgaggccgag gaccgcgagc cggaagttga tggtggtgaa gcggtcggcg
     1561 ccgaggctga tcccgagggt ctggaagagg ccgagggagg tgaacacgat gatgacggtg
     1621 agggggatgt tgcggacgat ggtgacgtag gcggtgccga agccccgcat gagggggacg
     1681 gggccgacgc gcatggcggc gagcagcgtc ccccagacga gggagcccag ggcggaccag
     1741 aaggtgagct ggacggtcac ccagaaggca cccaggaggt cgtagccttc gaggaagtcg
     1801 aacacggcgg ccggcctact cgacgatcac gccgatcttc ggggccggtt cgttctggta
     1861 gttcgccgga ccgaagttct tctcgacggc ctcgtcccag gagccgtcct cgaccatctt
     1921 ctccagagcg gtgttgatct cgcccttgag gtcgctgccc ttctggacgc cgatgccgta
     1981 gttctcgttg ctcagctcga agccgccgag cttgaacttg cccttgaacc cctcctgggc
     2041 ggcgtagccg gcgaggatcg agtcgtcggt ggtgagggcg tcgatgacgc cgttctccag
     2101 gccggtcagg cactcggagt agccgccgta ctcctggagc tgggcgtcgg gggcgatctc
     2161 ctccttgacg ttctgcgcgg aggtggagcc ggtgacggag cagagccgct tgtcgttcag
     2221 gtcggacggc tgcttgatgg agtcgtcgtc ggcgcggatc aggacgtcct ggtgggcgag
     2281 gaggtagggg ccggcgaagt cgaccttctc ggcgcgctcg tcgttgatcg agtaggaggc
     2341 ggcgatgaag tcgacgtcgc cgcgctggag catggtctcg cggtcggcgc tcttcgcctc
     2401 cttccagacg atctggtcgg gctcgtggcc gagttgcttc gcgatgtagg tggccacgtc
     2461 gacgtcgaag ccggtgtagg tgccgtccgg ggtcttcagg ccgatgcccg gctggtcgaa
     2521 cttgatgccg atggtgatct gatcgtcgtc gtcgtggtcc gccggtacgg ctccctgggc
     2581 gaccgaggcg gtgccgaggg cgaggacgac ggccgtcgcg gaggcgacga gggtccgggt
     2641 ggtcctgagc gggttcatgt gatcaccccg tgggggctca gtggtggagg atcttggaga
     2701 ggaagtcgcg ggcgcgggcg ctgcgcgggt tgccgaagaa ctcctcgggg gtggcctcct
     2761 cgacgatccg cccgtcggac atgaagacga cgcggttggc ggcggagcgg gcgaagccca
     2821 tctcgtgggt cacgacgacc atggtcatcc cgtcccgggc gagctgccgc atgacctcca
     2881 ggacctcgtt gatcatctcc gggtcgaggg cggaggtcgg ctcgtcgaag agcatcacct
     2941 tcgggtccat cgcgagggcc cgggcgatgg cgacccgctg ctgctggccg ccggagagct
     3001 gagccgggta cttcgcggcc tgcgcggcga cgccgacgcg gtcgaggagc gaacgggccc
     3061 tctcctccgc ggccttccgg tccttcttgc ggaccttgat ctgtcccagg gtgacgttgt
     3121 ccaggacggt cttgtgggcg aagaggttga acgactggaa gaccatgccg acgtcggccc
     3181 ggaggcgggc gagttccctg ccctctgcgg gcagcggccg gccgtcgacc cggatctcgc
     3241 cgctgtcgat ggtctccagg cggttgatcg cgcggcagag ggtggacttc cccgagccgg
     3301 acgggccgat gacgacgacg acctcgccgc gccggatggt gaggtcgatg gactggagga
     3361 cgtgcagcgt cccgaagtac ttgtcgaccc cgcgcagcac gacgagcgcg tcgccgtcgc
     3421 ccgcgacggg gtcgtgctcg gtgacgggga cctccgggac gggcatgtca ccctcctgtc
     3481 gccctcctgg ctcacgcccc ctcgtgccgc ttcctcctcg gtctcatgct ccgcctcccc
     3541 gggtgccggc gcacgccggg acgggtgggg gaccccggcg gcgtctgccg ccggtggggt
     3601 gagcccgcgc ccgcgccgcc tgcgttccgg gcgcggtggg cggagactgg gaatcggagg
     3661 cgtacgcgcg aggaggaggg cccgtcatga ggagtgccgc acccaaggtc ggttcgctgc
     3721 cggcggagca ccgcgagcgg ctgatggcct tcgccgagga cgtctacttc gattccggtg
     3781 accggctctt cgaggagcag cggcacgcgg accggttctg gatcgtgaag acgggcgcgg
     3841 tgaatctgga cgccaaggtg ccggggcggg gggcgccggt gatcgagacg ctgcgccacg
     3901 gcgagctggt gggcctgtcc tggctgttcc cgccgtatct gtgccagtcg ggggcggagg
     3961 cgatgacccc cgtcagggcg tacgagttcg acgcgacggc ggtacgggcg atgtgccaca
     4021 cggacgtgga gttcgggtcg gcggtctact actgggtcgg gtcgatcctg gcgcaccggc
     4081 tccaggtgac gcgggtgcgg ctgctcgacc tgtacgcgcc gcacggcagc ggcatcatgg
     4141 cctgacgcgc agacgcgctg acgcgctgac gcgccccgcg cgcgggcgtc ggcctctcgc
     4201 cgcgcacgtg cgtcggcctc tcggggcgcg ggccgtacgg tccgggcggc cttcccgccg
     4261 taccgctccg ccgccgacgt caggagcacc gcatggcccc gcccgccggg cggacgctca
     4321 cgccggccgg agccgagatc ctgctggtgc ggcgggccgg tccgggcgcg ctcgccacgg
     4381 gcgaggtccg gtacgtggtg ccgctgacga cggccggctg cggcctgctg gtcctgggcg
     4441 atccgcgcgc cgacggcggc tgtacggaac cgtcggcgtg ctcgcctcgc tcgcctgggc
     4501 ggggcgctgg cgctgggctg gagagaggga ggacgggccg cgggacggtc ggcgggccgg
     4561 gcggagtgat cttcgccgca ccgggagtgc ggggccttcc cggccggcta ctcggcggta
     4621 cggtgacggc acccggcggc gtgacccggc gtacccggcc agtgcctgtc cgatcattcg
     4681 cgtcggatca gtcggatcat tcgcgtcgga cccggcggga atcgtcagac aggccctacg
     4741 ggcgggaggc ccccgatgac agcagctccg agcgcgcgcg aggcactggc cctcgtcacc
     4801 gacgacttca ccgagctccc ctccgccgcg gggcccggcg gcgacgggcc gatcgactgg
     4861 ccggggtacg gacgggcgcg ggccgcggcg gccgcccggt ccggcgagga cgagtccgtg
     4921 gtctgcggca ccggcacggt cggcggcacg cgtacggtgc tcgtctcctt cgagttcggc
     4981 tacctgggcg gttccatcgg cgagggcacc ggggaccggg tcgccgccgc gcacgcgcac
     5041 gcccgcgccc accggctgcc cgtgaccgtc ctcctggcga ccggcggcag ccggatgcac
     5101 gagggcatgc gggcgctggt ccagctccag cggctggccg gggagtcggc gctcacccgg
     5161 gccgccgggc tgccgcagct ggccgtcctg cgcgatccga cgaccggcgg cggctgggcc
     5221 accctcgggg ccggctcgga cgtggtcctc gcgctgccgg gcgcgcaggt cggcttcgcc
     5281 ggctcccggg tccggcccgg ggacgccgac ccggccgcgt acacggcgga gtcccagctc
     5341 gcgcacggac acgtcgacgc ggtcgtcccc gcggcggagc tgcgggaggt gctgggccgc
     5401 tggctgtcgc tgctcacccg gccggccgag gggccggtcc cgccgccgta cgcgctcggc
     5461 gccacggacc cggccgcgag cgggcgcgac gcggtggccc gcgcccgcca cccggagcgg
     5521 ccccgcgccg accgctacct cgccgaggtg ttcaccgagc gggcggagct gtccggcgac
     5581 cgcgtcggcg gcaccgatcc ggggacccgg tgcggcttcg gccgcctgcc ggacgggcgt
     5641 acggccgcgt acgcggcgca gtgcgggacg gcgacccggc cggccggctt ccgcacggcc
     5701 gcccggctgg tacggctcgc gggccgcctc gggatcccgg tcctgacgct gatcgacacc
     5761 ccgggcgccg cgaacgacgc cgaggcggag cgcgcgggcg cgggcccggc gatcgcggag
     5821 ctcttcggcg ccgtcgcgga ggcccccgtc ccggtgaccg cgctgctcgt gggcgagggc
     5881 ggctcgggcg gcgcactggc gctggcggcg cccggcaaca cctgggcgac cccggactcg
     5941 tacttctccg tcatcgcccc cgaactcgcc accgccatcc tgaagcgcgc cccggaggac
     6001 gcggacgcca ccgccgacga cctgcgcctg cgcccggacg acctggtcgc cctgggggtc
     6061 gtacggggcg tggtcggcgc ccggcccgcg ccggaccggg gcggcgcgga cggctgacac
     6121 ctgacgcctc cgggcgggcc gtgaccgagt ccccgtcccg gtcggccccg tccctccggg
     6181 accggccgga tcagtcgtcg tgccgtccgc cgccggcccg gcgccgggtc cagcggacca
     6241 ccatgcgcag gagcaggatc agcgtcacca cccacgcggc ggcgaaggcc cagatcaggg
     6301 ccggtgtcga ggtcgccacg gcgaggacga gcagggtgag cgtcagggcc ccgagagcca
     6361 cggcgcccac tccgccgcgc cccgcgatcc ggggcagccg ggggacctgc cggtgttccc
     6421 ccatgcggct ggccaggcgg tcgtcggcgc tcaggtccgc ctcgatctcg gccagtacgc
     6481 gccgctcgtg cgcggagagc cgggcctcgt ccatcgcgga cacctcctcc ggtccgggat
     6541 cccgcgcgcg acggcggggt cgctcccccg agcggctacc cgcccgggac ggcttcagac
     6601 ccgccggaac ggtcgggggc ggagcggtcg ggcgcggagc ggtcgggggc ggagcggggc
     6661 cacccgagtt ctcacggctt ctcacggcgc acggtccacc cgacctttta ctcaagggcc
     6721 aaaagggtca aaatgtgccg agtgggaatc ctctttacaa ggaggaatgt catggccacg
     6781 ggtcgagtcg tagacgcacc cccgcttccg tcgcccgcac gcgaagcgac gtcgacgtcc
     6841 gccgccacgc gccggcgggc actcgggggg ctgccggagc cggagaatcc gctctcgtcc
     6901 tccaccgacg acgcgcggac cctctccgcg gcgatgttcg tacggctccg ggagctcgac
     6961 gagggcagcc ccgagcacgc gtacgtgcgc aacaccctgg tcgagctgaa cctgagcctg
     7021 gtgaagttcg gcgcccggcg gttccggggc cgtccggagc cggtggagga catcgtgcag
     7081 gtggggacga tcgggctgat caaggcgatc gaccggttcg acccggaccg cggggtcgag
     7141 ttctccgcct tcgcgctgcc gacgatcgtc ggcgagatga aacgattctt ccgggacacc
     7201 ggctgggcgg tacgcgtgcc gcgccggctc caggagctgc ggatcgacct ggccaaggcc
     7261 tccgacgccc tggaacagcg cgacgggcac cggcccgacc gcgccgagct cgccgaacgg
     7321 ctgcacctca ccccggagga ggtggcggag ggggaactcg ccgccaacgg ctacaccgcc
     7381 cactccctcg acgcccccgt cggcgacgcc gagtcgcagg ccccccaggg gacggccgga
     7441 cggcgcaccg ccgtcgacga acccgcctac gagctgatag acgacctgag ctcgctgcga
     7501 ccgctgctcg accggctgtg cccccgcgac cggctgatcc tgtcgctgcg cttcggcgag
     7561 gagctgacac aggccgagat cggcaggcgg atcggactct cccagatgca cgtctcccgg
     7621 ctgctcgccc gcatcctcgg cgagctcagg gacggtctgc tggacgacga cgccacggag
     7681 gacgcgacgg cctgctgacc tccagccaca ccaccttgcc cgccgccccg ggcccccggt
     7741 ccgaggatcc ccagtcggtc gccagccggt ccaggaccat cagcccgtgt ccgccgggca
     7801 gggacggcga acggggggcg agtcggcggg gatggtcggg gctgcggtcg gcgacctcga
     7861 cccggagcag cccgtccgcg tgccggagca cgaactcctc ggggccgccg ccgtgcagac
     7921 aggcgttggt caccacctcg gagaccagga gcaggacgtc ctcgacccgc tcccgggcca
     7981 gggcgctctc ggcgggggtc cagccccatt cggcgagcgc ctccgcggtg aagtcgcggc
     8041 agcgggagac cgcgcccacg ctgccgcgca gcagcaggcg gcgggtctgc gccacgggtg
     8101 tgccgccgcc tcgggtctcg tcgctctcgc gctcgcgcat gatgaccggc ggcccgtcag
     8161 accggatccc cgggacggcc gtccggcttc ccgggacggc cgtccggatc cctggggcgg
     8221 gcaccgcccg cccggggggc cgaagcgtca ccggggccgt cggctgccgg gccccggccg
     8281 tcgggcgggt cgtccgcgag ggcctcgtgg gcgtccgcgt acacccggaa gacgtgcagc
     8341 gcgccggtga tctcgaacat ccggtccacc ggggggcgca gtccggccag gtcgaggcgg
     8401 gcgcccgcct ccagggcccg ggcgcgggcc ctgagcagca ggttcaggcc ggtggagtcg
     8461 cagaagtcga gcccggcgca gtcgacgacg agccgtgccg cgtcggcgtg cttctccagg
     8521 gcggtgccga gcggttcggc cgtgtcgtgg tcgagttcgc cgagcggtgc cacgacgacg
     8581 gtctccccgc cccggtcgaa ccgtacgtcc accctgaggc ggcccggccg acccgtcggc
     8641 ggaccgctgc cgggcgcacc ctcctggcct tccccgccgt ccatgcacac ctcaccttca
     8701 ccgggtgagt ccattttcgg ccagtacgcc ccgccctgcg agcagagggc cggggcggcg
     8761 gctcagacgg tggacggggg cggcgtccag cggtggtggc gggcgacgcc cgtgtcgacg
     8821 ccgtactcct tcctcaggtg ctccgggacc gcgtagtgca tcacccggcc ccgggtgagc
     8881 gtggacagtt cgaagaccga ggtcaggtgg ccgatccggt ccagcgccca ggccgcgaac
     8941 ggcgacgcgt cctccaccga ctccaggact ccgagcagcg gcggcagcgc cttcaccgcg
     9001 gtgtcccagc ggctgcgggg cacgtcgagc cagtcgccga ccgtgtcgcc gacgaggtgg
     9061 cggatcaggg cggagaccac cgggtcgaag aaggtgccgg gcacgacgtc ctcgtacagg
     9121 tcgatcagct gccgggtcag caccacgccc tcctccgagg ggcccatgtg gcggaggagg
     9181 tagaggtcga ggaaggcgcg cgcctcgtcg agggtcttcg gtacgaccgt ctggtccacg
     9241 ccgaggatcg ccccgaccac ccgccaggcg taggagtacg cctccgctcc ctcggtggac
     9301 atgtggacgc cgagccggtg gaggctgtcg aggacgagca tcgagaagaa catctgcccg
     9361 ccgatcatgt cctcctggca gatcggcacg ccgtcggcgg ccgtgtccca gcggtcggcg
     9421 cggatcaggt ggtggcggat ggaggcgtgc aggagccgca ccttctgcgc ggcggggacg
     9481 aaccggccgc cggcctcgaa ggcgtcgggc cgcatgaggt acgtcgtgaa ctggccggtc
     9541 tccgccatgc gcttgctcgg gtagtgcagg ccgtgggtgg cggagagcag ccgggcgacg
     9601 cgcgggacga cgtagcaggc gggcatggag gcgaaggaga gggcggtgtt gatgtggacg
     9661 ttgttgtcgg tgaagaagag ccgggccttc tccatctcgt tccagtcgac ccaggcgggc
     9721 gggacggccg tcgcctccag gtactcccgg gccacgtcgg gcaggccggc ggggagctcc
     9781 tggccggaga cggagacgta ccgcatgagc gagttgaaga ggccgacctc accgcgttcg
     9841 aagagggtgg cgacgacggc gtcggcgagc tcgtcgccgc tgtggcggag ggcgtcgagg
     9901 gaggcgtcgg tgtacggggt gggggtgagg gtggctgtgg tgtgggtggc tgtgctgtgg
     9961 gtgccgggca cggcgggcgc tccagggggc ggtggggagg tcagtggtgg cggacggcgg
    10021 cgcggtgggc gaggtccgtg agggcgcggt gggcggcggc cggcaggtcg agctcgtcga
    10081 gggtgcggac ggcctcctcg acgcggccgg tgatcatgcg ctcgacccgt gcgggcgcgc
    10141 cgagtccggc catgagggcg cggacctcgc gcagttcgcc gtcgtcgggc cgccggtccc
    10201 cggcgagggt ccggcggagc agctcgcgct gcgcgggatc cgcggcgttc caggtctcgg
    10261 cgaggaggac ggtgggccgg gcggcgcgga ggtcgtcgag gggcgccttg ccggtgcggg
    10321 cggggtcgcc gaagaggccg aggaggtcgt cgcggagctg gaacgcctcg ccgagcggca
    10381 gcccgtagcg ggagaacccc tcgcggaggg cggcgggggc gccggcgagg agcccgccga
    10441 ggaggagggg gtgttcgacg gtgtacttgg cggtcttgta gcagatcacc ttgagggagg
    10501 tcccggtgtc cggcgggccg ccggtgtgca ggatctccag ggcctcgccg gcgacgagtt
    10561 cgcgcgcgag ggcggcccag aggggccggc cccgggagag gtacgcggcg ggcagcccgg
    10621 actccgcgta gaggcggccg gcgagggcca tcaggtggtc gccgaggagc agggcgagcg
    10681 cgcgggccgc cgcacggggc cttcggccga ggtgcggcag ggccgcgaag tggtggtggg
    10741 cggtgggtct gccgtgccgc agggggctgt cgtcgatgag gtcgtcgtgg acgacggcgg
    10801 cggcgtggac gagttccatg gcggccgcgg cccgcatcag ggcgtcgctg tcgggctgcc
    10861 ccgcggcccg ccagccccag tagcagaacg cggcgcggag gcgtttgccg tggcgggcgg
    10921 tggtgcgcag ggcctcggcg agcgggtcca gcgcgtcgtc gacggcgagg agtgcggtgg
    10981 cctcgtcgtc gaggaaaccg gcgaggaccg cgtccgtacg cgccttgaac tcctccggca
    11041 cccagacgtc aggcatcggg ggccgcctcg gtacggacct gccgggcctg tcgggtgtcc
    11101 ggatcggcgg cgggggcctg cgcggcggcc cggcgggcgg cggcctcgcg ggcgaggagc
    11161 tccatgtgcg gcacggaacg ggggccgtcg cggtcggcgg cgaggcggtc gagggccagc
    11221 cggccccggg cgcggaggtc ggcggcggcg tcctgggcga ggtcggcgga gtcggcgcgg
    11281 ccgaggagcg agcggagcga accggcggcg gtgccgatcg tctccacgac caggtcggcg
    11341 aggcccgcgg ccatcaacag ggccttctcg tcggggcgtt cgcccggggg cgtggggtgc
    11401 gtcatgccgg ccggctcctc ggggggagag agggggatcg aggtgggtac cgggccagca
    11461 tcgggcatgg gcgggggcgt tcccgagccg cgctcactcg ttcaggtgat cacggccggg
    11521 agttccggtg atcagggccg ggagttccgg tgatcgcggc gggatttccg gtgggaggag
    11581 cgtgaaggcg tctggaactt ccgctccgat ccgggtactt gcttggtcat gcttcgcacg
    11641 tccgcgggga ccgcaccccg ccccctcgcc cgccgcgccg cactcgccct ggtggcgtcc
    11701 gccgcggccc tcctgacggc gggctgccag ggcgtgcacc ggtgcacgct ggtcggcgcg
    11761 gagtcgggcg tgacggcgac ctggagcccg gcggacttcc ccgcgggctc gcgctacagg
    11821 atctgcgccg acgccgagtg ccgagagcgc gaggagccgg cgggcgggcg acggctccac
    11881 caccttcctc caggtgccgc tgccggagga ggacgggccg cgggaggtga cggtgcgctt
    11941 cgcggtcatc gccccgtacg gcgaacccga cggcgaaccg gccgacgacg agccggcggg
    12001 cggggacggg acccggccga aggcggccgg atcgtccgcg agtcctcggc gagggtcacg
    12061 ctgagcgggt cgaccccgaa cggcgagggg tgcggacccg ccgtctggca ggcgggggtc
    12121 cgcgtcgatc ctcggaaggg cctggtcagc cccgggtgag aggggcggcc gctacgggtg
    12181 agagtcgtgg gccgctacgg gacccagtga ttgccggaga ccgtgatcat cacctggagc
    12241 tggatgctgg cggagaagta gctgccggtg tcgatcgggg tggcggtcat cttgttccag
    12301 agggcgtcga gccaggcctg gctgccggag tcggtcatgg cggcgacggc gaagggggcg
    12361 aagaaggccg cctcgctgcc cgcggagatc tgggtgccgt tgagcttgta gcccatggcg
    12421 atcttgttgg ggtcgccgcc ggtcttgctc ttgatccagc cgttcagctt ccgtgcggcg
    12481 gcgagggact tggcgtcgcc gctggtgacg gcgtcgtcgg cgatgcgcca cggggtgcgg
    12541 caggcgttcc accagtactg gccgtcgttc gggtcctcca ggacctcgcc cggggccggc
    12601 ttggggctgg tgttcgtgtt gacgacgaag tcggggagca ggccggtgcc cggggcgtag
    12661 ccggactgga ggttggcgat ctgggtctgg tgggcggtgc gggccgcgtc ccaggtggtg
    12721 tcgccggtgg ccgcgcggaa ggcgcggaag tggtcgacca tccagtcgga ggtgcgggag
    12781 atgtagtagt actggtcgcc cgagctggac cagtcgccga gcttgaggag cttggtggtg
    12841 gggttcagct cgtccttctt gatggcggcg atgtgcttga gggcgagcgc cttgtagtcg
    12901 tacgtgccgg cgctgcccca ctgcttgtcg gcgaggagca ggccgtaggc gacgtccatg
    12961 tcgccgtcgg tggcgccgtc gccgccgttg acgctgcggc agtcgacgtc ctgttcggcg
    13021 gcgaggaggt cggggttgat ggacgagggg tggtcgagct tccacttgac gaggccgtcg
    13081 aagatcttct tggcgtcggg gtcggcgccc gccatggtgg cggcgatgac catgccgtag
    13141 ccctgggcct cggcgacgta ggggtggtcg gcgtcgggcg agatgacctg gtaccagccg
    13201 ttgccgcagt tctgccggac gaaggcggac ttccagcggt tgtagtagtc gacgaccttc
    13261 tggtcgatgc cggactgggt gccggagggc ttgagcatgc cggcggcgta gggcttgagg
    13321 tggctgccga aggggacgcc ggggccggtg ccgcctccgc cgccggtcgg ggagccgtag
    13381 acctcgaact cgtagagcga gtagccgtac ggggtgccgc ggccggtccc gtacatgcgg
    13441 acgtaccggc cggtgccgga gacggcgagg tcgtcgacgg cgccgtcgcc gctcgtggtc
    13501 gcgtagacgt cggtccaggt ggagccgtcg gccgaggtct ggaggcggta cgtcttcgcg
    13561 taggcggctt cccagtcgag cttgatccgg gagagcgtgt ggttcgcccc gaggtcgatc
    13621 cggatccact gcggatcgac gccctccagg ctggcccagc gggtggcgcg gctgccgtcc
    13681 acggcgaggc cgggggcgaa gcccgagccc tccacggacg aggacgtcgc cggcttgccc
    13741 gcggagacga gggcgtcgac ggcctcggcc tcgctcgcgg gcaggacggt gagtgcgggc
    13801 agggccagca gagcggcgag tccgagcggg atggcgcttc gtcggcgcat gacaactccc
    13861 tttctctcca gggcgatcgc tcgttaggaa aggttcctaa ttatcggcgg gccgagcgta
    13921 gagagtggcg gggagcccgc gcaagaccct gggcccggcc gggtcggtgg atggccggga
    13981 atcaccccgg cagcgtcagg gcgcgggcga gggcggaggc gaagccgtcg gggttgtcga
    14041 gcatcaggtt gtgcccggcg gcgggcacct ccaggacggg cacgcccatc tccgccgcct
    14101 gctcggcggc ccggtccggc aggctcttct cccccaccag gaacgcccgg ggcagcgtca
    14161 gcgcccgcag cacctcgccg gcctccgggt cgccgccctc gacgagcgcg accgcgcacc
    14221 ggtgcacggc ccgcgcgtcg gcgagcctca accgcgccgc gtagtcggcc cgttcggcga
    14281 gggccagcag cttcgcgtac ccgctccgga cgaaggcctc ctccggctgc cgcgccaccg
    14341 gcccgctgaa cgcgccgccg cccccgtaca ggttgggctc cgcgaccacc agccgggcga
    14401 cccgcccggg ccgggccgcc gccaggtgga tcgcgacggc accgcccatc gagtgcccga
    14461 ccaactcgac gccacgcagg tcgagatggt cgagcagcgc ggccaccgcc gccgcctgcc
    14521 cctcgggccg gtagtcgaag tcccccggcc ggtcgctcag cccgtgcccc agcagatcga
    14581 cgagcagcgc ccgcccgcct cccagcgcgg ggtgcgtcgc gatgtgcgcg aagtcggagg
    14641 cggcggtaca cccgagccca tgaagaaaga cccgcacggg cccctccccc ggaaggtcga
    14701 tccagcgcag gtgggcctga cggtccgcca ggaagagttc tctcatgggg gcagcctacg
    14761 aagggggtgg ggggtggcgg tgggggttgt gcgggcgctg gggcgtgggg tggcgcgagg
    14821 gctgtgagac tccgcggcgg ggcgcgagtg tgcggcgggg cacggacggc ggaagggagg
    14881 tgctgcgagc gcggggcgct gcgctacggt ggccttccat ggcatcgagc accgcgttct
    14941 ggtccttcgc tctcgtcgtg ggactcctca ctctcactcc gggcctcgac acggccctca
    15001 tcctgcggac ggccgcgctc ggccgccgca cccgcgcctg gggtgtcgtc ctcggcatcc
    15061 agaccggcac gctgatctgg ggcgcgctga cctcgctggg cgtgacggcg ctgctgaccg
    15121 cctcgcacct cgcgtacgag atcctccggt gggcgggcgc ggcctatctg ctgtggatgg
    15181 cggggcgcat gatcgccgaa acgttccggc gccgtggggc ggacgcgagc gcggaggtgg
    15241 aggtcggcgg cgcggacacg ctcacgggcg ggtggcacca gggcacgctg accaatctgc
    15301 tgaaccccaa ggtcggcgtc ttctacgtcg ccgtgcttcc gcagttcatc ccagccgagg
    15361 ccccgcactt cgcgatgggc ctcgcgctga cgtccgtcca cgtcgtcctc ggcgtggtct
    15421 ggtcgacggt cctgatcgcc tccgcctccg ccctcggcac ctggctgcgc ggcgcgcggg
    15481 cccggcgcgt cctggaccgg gtcacgggca cggtgatcgg cgcgttcgcg gtacggctcg
    15541 cggtcagcga ctgacggacg gggccgggcg gcggccgacg cgcccggtcg gccgggcggc
    15601 cgctcacggc tccggcagga gcctcgccat ctcggtgggc ggcagggacg gatgggccgc
    15661 tgccgcctcc cgcacggcct cgtccgcgtc cgcgtccgcg agcagtccgc ggagtaccgc
    15721 cggcgggagc gccggatgac cggcggcgaa ggggcgcgcc cgggcgtccg ccaggcagac
    15781 gaggagcgcc gggggcgtga cggcgcggtg ccggtcgatc tcgcggagcg ctccgcgcac
    15841 cggcggctgg tgccgggcga gttcctccag cagggccgcg ggcgtgtccg ggttggccgc
    15901 caccccggcc atcacctggc gcccgtgccg tacgaccatg gcccgcagcc gcgcctcgga
    15961 gagacccggg tgcggggcga cggccgccgc caccttcgcg tcggggtcgt cggccagccg
    16021 gtcccgcgcc cctgtcggca gatcgcgccg gagggcgacg agccgccggg cggccggctc
    16081 ggcggaggcg accagttccc cggtctcgtc ggccgacgcg gtggcgatcc gcgggaggag
    16141 gacggtgccg agcgcggtgg tacgggccag cgggacgagc acgtcgagcg ggacgcgggg
    16201 gtgccgggcg accgcacggc gtatctcggg atcggggtcg tccgccaggc tccgtacgag
    16261 gtcgccgtcg agggcggggt tctcggcgag ggcggcgcgg accaggggaa gcgggtccgc
    16321 ggcgagccgt acgcaggcgt cccgtgacag gtccgctctc ccggccaccg cccagcgcag
    16381 cagcgggtgg gggtcgtcgg cgaagcgggc ggcggcctgc ggcggagtgg ccgggttgcg
    16441 caggagggac tcgcgcaggt ggacgacagc ggactcgtgg tcgccgccgc agcgctcacc
    16501 gggcggcagg acgggccccg tcgtctcccc ctcgacggcg cagacccggc atcggcgggc
    16561 cggtggcagg ccctcgccgg tcaggaggga agccaggacg gcgggcgggg tcgtgtcgtt
    16621 ctccgccacc gcgcggcgca ccgagaggtg ggggtgggcc gcgaggcggg cggccatgtc
    16681 ggcgggcccc agccaggccg actcggcgac cacgctcggg accgggtccc gcgccagccg
    16741 ttcggtcacg tcgggcggga gcccagggca ggccgccagc cgctcccggc gcccggggtc
    16801 cgggtccccc gcgaacgccc gcgcccacgc ggcgggcgcc gcaccccggt ccagcagcgc
    16861 gagggcggcc tccggccact ccgcgggatc gacgtcggca gcggccagcc tcccctcgta
    16921 cgcgagggac accgcggccg cgtccccgac tcgccgggcc agggcgagcg cccgaccgcg
    16981 gtcgaggtcg gtccggcggg ccagggcgcc cgcgagttcg tcgtccgcga gggctatgag
    17041 ccggtcgagc aacgcggagg gcagggccgg attcgcggcg agtccgtgca ggagtgcgta
    17101 cacgaccggc attctgccgg tcggggcggg ccggacgccc ccggatttcc cctccaggat
    17161 ttcggatcga ggatttcgga tccaggacgt tggatccagg acgttggatc caagattctg
    17221 gatccaagat tcggaatccg ggatccaaga ttcgggatcc gggatatccg ctccacgcgg
    17281 gaacgggtgg agcgcccccg ggaagggcgt gggcggacta cttgtactgg gtgagctgga
    17341 tcaggttgcc gcaggtgtcg tcgaggatgg cggtggtgac ggggcccatg tccacggggg
    17401 gctgggtgaa gcggacgccc agtgcggtga ggcgggtgtg ttcggcgtgg acgtcgtcga
    17461 cggcgaagga ggtcgcgggg atgccgtcgg cgacgagggc ggccttgtag ggcgggacgg
    17521 cggggtggcc ggacggttcc aggaggagtt cggtgccttc ggggtcctcg ggggagacga
    17581 cggtgatcca gcggtcctcg ccgagcggca cgtcgtgctt ggtcgcgaag ccgagcacgt
    17641 cggtgtagaa gcggagcgcc gtctcctggt cgtcgacgaa gacgctggtg atgttgatcc
    17701 tcatggggtg tcctcggggg gtgcgggggt gagccatcgc gtgacgatgt gctcaagggg
    17761 gcgggggtcg aggtcgtgga acttgtagcg gccctcgcga cggggcgtga ccagtccggc
    17821 ggtctccagc accgcgaggt gctggctgac cgcctgccgg gagatggcga ggccgtgccg
    17881 ggtcgcgagg cgggcgcata tctcgaagag cgactgcccg ttgcgttcgg tcagctcgtc
    17941 gaggatcacc cggcgcgtcg ggtcggccag cgccttgaac agatcctcct ccatgccgcc
    18001 accataggca agcatgcact tgcctatcaa gtcgacgggc cgctcctcga tcagctctgc
    18061 ccgccgcgcg aagcccgcct aaggtggtcg catacccgcc cacccctgac gagggagaaa
    18121 cctttgagca cggccaagcg gagcggcgcc gcgaccccgc ccacggcaca cgtcgccgac
    18181 agccacgagc tgatccgggt ggtcggcgcg cgcgagaaca acctcaagga cgtcagcgtc
    18241 gagatcccca agcggcggct gacggtcttc accggagtct ccggctccgg caagagctcg
    18301 ctggtcttcg acacgatcgc cgccgagtcc cagcggctga tcaacgagac gtacagcgcc
    18361 ttcgtccagg ggttcatgcc gacgctggcg cgcccggacg tcgacgtgct cgacggcctg
    18421 accaccgcga tcatcgtcga ccagcagcgg atgggcgccg acccgcgctc caccgtcggc
    18481 accgccaccg acgccaacgc gatgctgcgc atcctcttca gccggctcgg caccccgcac
    18541 atcggctcgt cccgggcctt ctccttcaac gtcccctcgg tgagcggcgc gggctcggtc
    18601 accgtggagc gcggcggccg gacggtgaag gagaaggcga gcttccagat caccggcggc
    18661 atgtgcccgc gttgcgaggg tcgcggccgg gtctcggaca tcgacctggc ggagctgtac
    18721 gacgacacca agtcgctcga cgagggcgcg ctcaccatcc ccgggtacac ggcggacagc
    18781 tggtacggcc gcacctaccg cctctccggg ctgctcgacc cggcgaagcc gatccggaag
    18841 tacaacaagc gggagctgga gaccctgctc tacaaggagg cgacccgggt caaggtcgag
    18901 ggggtcaacg tcacgtacga gggcctgatc cccaagctgc agaagtcctt ccttgccaag
    18961 gacgtcgagt cgctccagcc gcacatccgg gccttcgtgg agcgggccac caccacccag
    19021 gtgtgtccgg agtgcgacgg cacccggctc aacgaagggg cccgttcctc gaagatcaag
    19081 gggatcagca tcgcggacgc ctgcgcgatg cagatcagcg atctcgccgt gtgggtgggc
    19141 gagttggacg attcctcggt ggcgccgctg ctggagtcgc tgcggcggac gctggactcg
    19201 ttcgtggaga tcgggctcgg ctacctggcg ctcgaccggc ccgcgggcac cctgtcgggc
    19261 ggcgaggcgc agcgcgtgaa gatgatccgg cacctgggct cctcgctcac cgacgtcacc
    19321 tacgtcttcg acgagccgac ggccggtctg cacccgcacg acatccagcg gatgaacgaa
    19381 ctcctgctgc ggctgcggga caagggcaac acggtcctgg tcgtggagca caagccggag
    19441 acgatcgcga tcgccgacca cgtcgtcgac ctgggacccg gcgcgggcac gggcggcggc
    19501 acgatctcgt acgaggggac gctcgaaggg ctgcgcggca gcggcacggt gacgggccgt
    19561 cacctggacg accgggcctc ggtgaaggac gcggtgcgca cgccgaccgg tgccctggcg
    19621 atccgcggcg cgaccgcgaa caacctgcgg aaggtcgacg tcgacctgcc gctcggcgtg
    19681 ctcgccgtgg tcaccggcgt ggccggctcc ggcaagagct cgctggtgca cggctcgatc
    19741 ccggcggacg ccggggtgat ctcggtcgac cagaccccga tccgcggctc gcggcgcagc
    19801 aacccggcga cgtacacggg tgtgctcgac ccgatccgca aggccttcgc caaggccaac
    19861 ggcgtcaagc cggcgctgtt cagcgccaat tcggagggcg cctgcccgac gtgcaacggc
    19921 gccggggtca cgtacaccga cctggcgatg atggcgggcg tggcgaccac ctgcgaggag
    19981 tgcgagggcc gccggttcat ggcctcggtc ctggagtaca agctcggcgg gcgggacatc
    20041 agcgaggtgc tggcgatgcc ggtgtcggag gcggaggagt acttcggcgc gggcgaggcc
    20101 cgtacgccgg cggcgcaccg gatcctggag cggctggtgg acgtcggcct cggctacctc
    20161 acgctgggcc agccgctgac gacgctctcg ggcggcgagc ggcagcgtct gaaactggcc
    20221 acgcacatgg gcgacaaggg cggggtgtac gtgctcgacg agccgaccac cggcctccac
    20281 ctcgccgatg tggagcagct gctcgcgctg ctcgaccggc tggtcgactc cgggaagtcg
    20341 gtgatcgtgg tcgagcacca ccaggccgtg atggcgcacg ccgactggat cgtggacctc
    20401 ggcccgggcg cgggccacga cggcggtcag atcgtcttcg agggcacccc cgccgacctg
    20461 gtcgccgccc gctcgacgct gacgggcgag catctggcgc agtacgtcgg cgcctgaccc
    20521 cgcgtccgcg cctgatcccg tgtcggcgcc tgacccccgt gggcccgatc ctgatcaggt
    20581 ccggccggcg aggagcgccg agggcggcag gaggaccggt tcggcggtcg ccgccaccgc
    20641 cgccgcgacc acggcggcac ggtggcggtc cgtccactcc ttgagatgta cgtcctccgg
    20701 gggtgggcgg cccgccttga agcgggcctc cgcgcggacc caggcgcgca ggagcgcggg
    20761 gcccgggtcg ggggcggcca gggcctcgcg gaggtcgggt ccgggaagga cgcggcggag
    20821 gacggggagg gggccggggc gccgggcggc cggttccacg tcgacgccga ccgggccggg
    20881 ggcggcggcc gccgcgacca ggccgtcggc gtggctgacg ctcacaccga gcccggggtg
    20941 cgcggggagg tacgggcggc cgtggccggc ccggccgcag tcggggcagc gctgggcgag
    21001 gccgagcgcg gcgggcgggc ggccggtggc gcgggcggcg cagaggcgga gcagga
//
