LOCUS       NZ_JABBGE010000004     22595 bp    DNA     linear   CON 22-MAY-2024
DEFINITION  Streptomyces sp. R302 contig4, whole genome shotgun sequence.
ACCESSION   NZ_JABBGE010000004
VERSION     NZ_JABBGE010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. R302
  ORGANISM  Streptomyces sp. R302
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 676282)
  AUTHORS   Dahal,R.H.
  TITLE     Streptomyces sp. R302 sp. nov., isolated from soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 676282)
  AUTHORS   Dahal,R.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) Life Science, Kyonggi University, Kyonggi
            University, Suwon, Gyeonggi-Do 16227, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2020
            Assembly Method                   :: SPAdes v. APR-2020
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 180.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012927245.1-RS_2024_05_22
            Annotation Date                   :: 05/22/2024 03:52:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,357
            CDSs (total)                      :: 7,271
            Genes (coding)                    :: 7,075
            CDSs (with protein)               :: 7,075
            Genes (RNA)                       :: 86
            rRNAs                             :: 5, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4 (5S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 196
            CDSs (without protein)            :: 196
            Pseudo Genes (ambiguous residues) :: 0 of 196
            Pseudo Genes (frameshifted)       :: 84 of 196
            Pseudo Genes (incomplete)         :: 164 of 196
            Pseudo Genes (internal stop)      :: 20 of 196
            Pseudo Genes (multiple problems)  :: 67 of 196
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 439304
            Orig. end                         :: 461899
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABBGE010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22595
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyanobactin"
                     /region_number="5"
                     /rules="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /tool="antismash"
     cand_cluster    1..22595
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /kind="single"
                     /product="cyanobactin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22595
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12595](-)"
                     /cutoff="20000"
                     /detection_rule="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /neighbourhood="10000"
                     /product="cyanobactin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12595)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cyanobactin_synth or TIGR03678 or
                     cyanobactin_precursor)"
                     /neighbourhood="10000"
                     /product="cyanobactin"
                     /protocluster_number="1"
     misc_feature    complement(315..329)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.53"
                     /tool="antismash"
     gene            1194..2474
                     /locus_tag="HHL19_RS14970"
                     /old_locus_tag="HHL19_14975"
     CDS             1194..2474
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081245.1"
                     /locus_tag="HHL19_RS14970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_14975"
                     /product="cation:proton antiporter"
                     /protein_id="WP_169089630.1"
                     /transl_table=11
                     /translation="MTFVLIVITAVTAGWALVARRLERGHVRAPVVLVLAGVVTGVFTH
                     SRIAVTLNSEIAQHVAEVILAVLLFVDATELPGGRLFGNDPGEAARTLLVALPLSLAAV
                     VLLGTLLLPGLPAVILLIIAGIIVPTDFAPAETLVRDTRIAARVRDVLNVESGYTDGII
                     SPVFLFALILAGSTSQAHTPVQALATAVPFAAKALAVGVALGSLLAWLMTTADRRQWMT
                     GQSRRVLVLVTPLLVHTVTVAAGGNGFVAAFVCGIAFRYVRQTPARRHESYVPDASDFR
                     LVEDTGSIMAMCMWFFFGNATVLALSEGIDVPTVLLCLAALTVVRVGPILFAFLGSAFT
                     GRERLMIGTLGPRGTTSIVFGLLAFNALPDGPSADTALYAMTVTVLGSALLHGLGSTPL
                     ARLLTAPAPAPTPAPVPASPAGPEKVR"
     gene            complement(2496..4283)
                     /locus_tag="HHL19_RS14975"
                     /old_locus_tag="HHL19_14980"
     CDS             complement(2496..4283)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010032219.1"
                     /locus_tag="HHL19_RS14975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_14980"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_169089632.1"
                     /transl_table=11
                     /translation="MNTASAPETTGAESLRVRETLKALYGYVRPHRWAVVLGLLLALVG
                     AAGGLLQPLATKELVDRLSSGGTLAAVLLALTVLVLLSTVAEAFGAYVLERTAESVVLA
                     ARRSLIGRMLRLRLSAVDRTQPGDLMARVTSDTTLLRAVSTQAVVNAATGALTLIAAVV
                     VMAFLDVVLLGVTLGVVVVVGAGAALVMPRIGRAAERSQAAVGEMSTGLERVFGAFRTV
                     KASGAEERETARVEASARRAWRHGVRGAKWEALLGTADNLAVELAFLAVLAVGGARVAS
                     GDIPVSTLIAFLLYLFYLMEPVYKLVEAASAYQEGAAAISRIKEVDRLAAEPPATYEPV
                     RTEARPASVRFEDVSFRYGPGLPYIHQRVDFEVPGAGLTAFVGPSGAGKSTVFSLIERF
                     YETTGGRVLVDGTDIRQWPLSALRSAIGYVEQDAPVLAGTLRENLVFSAPGATDDDIRA
                     VLARTRLDTLVERLPHGLDTPVGHRGSKLSGGERQRVAIARALLRKPRLLLLDEATSQL
                     DAVNELALRDVIGETARETTVLVVAHRLSTVTDADRIVVMDAGTVRAIGTHEELVAEDE
                     LYAQLAATQFLTPAGRPVG"
     gene            complement(4513..5418)
                     /locus_tag="HHL19_RS14980"
                     /old_locus_tag="HHL19_14985"
     CDS             complement(4513..5418)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984178.1"
                     /locus_tag="HHL19_RS14980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_14985"
                     /product="poly-gamma-glutamate hydrolase family protein"
                     /protein_id="WP_169089634.1"
                     /transl_table=11
                     /translation="MTLTSRRTLLTSVAAAAASLPLLNDLAGNGGTAAAATTATEFPTN
                     AALYSSTEYREGVHWMRRFRTHAQGLLLDNASASSSVIRSTAVIAPHGGGIEPGTSELC
                     LTLAGYSRVGAGTDPVADSAVPQRDYWMFEGIASSSSLHVTSTHCDDPAALAVCAANLY
                     AVSLHGFAPDAGTPAKQILIGGRDTRLMRNLAAAFAGHGLTTGNADPALDVTVTVAGVN
                     SPLNGDDPDNIVNRTRTGAGAQLEISTELRRAMFGDFSGASGRRTSAGVGTAHEAHFWN
                     GFVDAVREAVDRHERGLDSL"
     gene            5631..6044
                     /locus_tag="HHL19_RS14985"
                     /old_locus_tag="HHL19_14990"
     CDS             5631..6044
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972162.1"
                     /locus_tag="HHL19_RS14985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_14990"
                     /product="VOC family protein"
                     /protein_id="WP_169089636.1"
                     /transl_table=11
                     /translation="MASRLNPYLSFTGSAKQALDFYQDVFGGEPVVNTYSQFGEAPPGF
                     ADKIMHGMLETPAGFTLMVSDTPPGMDHTPGSTISISVSGDDEAELRGYWEKLSARGTV
                     SVPLEKQMWGDVFGMCTDEFGVVWMVDITAEPS"
     tRNA            6142..6226
                     /anticodon=(pos:445479..445481,aa:Leu,seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HHL19_RS14990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="HHL19_14995"
                     /product="tRNA-Leu"
     gene            6142..6226
                     /locus_tag="HHL19_RS14990"
                     /old_locus_tag="HHL19_14995"
     gene            complement(6298..7095)
                     /locus_tag="HHL19_RS14995"
                     /old_locus_tag="HHL19_15000"
     CDS             complement(6298..7095)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037459.1"
                     /locus_tag="HHL19_RS14995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15000"
                     /product="serine protease"
                     /protein_id="WP_346768349.1"
                     /transl_table=11
                     /translation="MRTVAAALAGLVLGVMPGAPREAAAVVGGQEAAPGAYPYVAALVD
                     VERHRQFCGGALIGTRHVLTAAHCLSGSYADTRRVAVLLGDHDLRTATESRHARVARPV
                     RFTVHPGYDSRTQHDDLAVITLSDPVRPDAGVRPIALPTPAETFDHTRLEAVGWGATAF
                     GEGPSPVLRTVTLDTVPHAACARRDVGPLTPAQLCTWTPGRDTCVYDSGGPLSHRTGTG
                     RPVLAALVSYGRGCATDTPAVNTRITSHLAWIARTTGVRPPAA"
     gene            complement(7390..8445)
                     /locus_tag="HHL19_RS15000"
                     /old_locus_tag="HHL19_15005"
     CDS             complement(7390..8445)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675961.1"
                     /locus_tag="HHL19_RS15000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15005"
                     /product="biotin/lipoate A/B protein ligase family protein"
                     /protein_id="WP_169089640.1"
                     /transl_table=11
                     /translation="MHGEYKAPGGKLVVVDLDVEDGALRRVRVAGDFFLEPDEAILSID
                     RALEGAPADTDAAGLAARIDAALPPGTQMYGLTSEGVGVAVRRALAHATDWTDYDWQLI
                     HEPPQSPALHMALDEVITAEVADGRRPPTLRVWEWGAPAVVIGSFQSLRNEVDPEAAER
                     HGIRVVRRISGGGAMFIEPGNTITYSLSVPDALVQGLSFADSYAYLDDWVLGALGDMGV
                     KAWYQPLNDIATEAGKIAGAAQKRMVTGAGAVLHHVTMAYDIDADKMTEVLRIGREKLS
                     DKGTRSAKKRVDPLRRQTGLSREAVIERMIASFRQRYGLTEGRVTEEELAAAKELAEGK
                     FSSPEWTARVP"
     gene            complement(8562..8870)
                     /locus_tag="HHL19_RS15005"
                     /old_locus_tag="HHL19_15010"
     CDS             complement(8562..8870)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS15005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_15010"
                     /product="hypothetical protein"
                     /protein_id="WP_169089642.1"
                     /transl_table=11
                     /translation="MNDTHQAVPPPAGTGPNLPVLGAVERRWDTYRPFLKDVRVYYYRT
                     DEEDPDTEVAGYVSEEPPPKSNFGSDVNDPPWAGAADRGWNCPSGEGADACTWLGPL"
     gene            complement(8933..9121)
                     /locus_tag="HHL19_RS15010"
                     /old_locus_tag="HHL19_15015"
     CDS             complement(8933..9121)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS15010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_15015"
                     /product="hypothetical protein"
                     /protein_id="WP_169089644.1"
                     /transl_table=11
                     /translation="MNKDFPARAAPAAVVRAPVQAPAVDRTRPAPLAAGTGHGGGVEAD
                     FAWLLPLATKAIGAFFK"
     gene            complement(9210..9404)
                     /locus_tag="HHL19_RS15015"
                     /old_locus_tag="HHL19_15020"
     CDS             complement(9210..9404)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS15015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_15020"
                     /product="hypothetical protein"
                     /protein_id="WP_169089646.1"
                     /transl_table=11
                     /translation="MNSEFPDTAAPRPPLQTPAVDRSPSAPARAGAGSQGAEANWEVPW
                     QLIGHGAKGMLDAWLSRQA"
     gene            complement(9496..9684)
                     /locus_tag="HHL19_RS15020"
                     /old_locus_tag="HHL19_15025"
     CDS             complement(9496..9684)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS15020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_15025"
                     /product="hypothetical protein"
                     /protein_id="WP_169089648.1"
                     /transl_table=11
                     /translation="MNEPFTRYEERPAPAGAPQTPFQTPAIDRSPAGPANAGEAADGVQ
                     ANFGLGDIWNIAKKVLF"
     gene            complement(9774..9974)
                     /locus_tag="HHL19_RS15025"
                     /old_locus_tag="HHL19_15030"
     CDS             complement(9774..9974)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS15025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_15030"
                     /product="hypothetical protein"
                     /protein_id="WP_169089650.1"
                     /transl_table=11
                     /translation="MDTTTSPTPSLPPQALPVVRDPWRQPRQGPDQGAEGAEGVQAARS
                     GCADLWGPARQMCYAQRSYAL"
     gene            complement(10001..12595)
                     /locus_tag="HHL19_RS15030"
                     /old_locus_tag="HHL19_15035"
     CDS             complement(10001..12595)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyanobactin: cyanobactin_synth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="HHL19_RS15030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15035"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_169089652.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4e-20, bitscore:
                     67.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="cyanobactin_synth (E-value: 7.5e-28,
                     bitscore: 92.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIRSVVRGVAGRGELLGSPEVRVAVLDGPVDLAHPCLAGADLTR
                     LPTLVSEPAGTGPMSLHGTHVTSLLFGQPASGMTGLVPRCTGLLLPVFRESPDGRVTRV
                     PQLDLARAVEQAVEAGAHVVNVSGGERTPAGTPNSMLERALRLCADRGVLVVAAVGNDG
                     CDCLQAPAATPSVLAVGAADATGAPLGINNWGGAYRLNGVVAPGRDIRGAAPGGGFASL
                     TGSSFAAPAVTGVVALLVARQLATGHAADPIAAGRAVLESALRPPCDPDDAPECRRLLR
                     GLLNAPGAFALVDGDGAPAPVAAGASPAGPRERVIVMDTNAVHPQVAQPPDPLPADART
                     APAAVPQEAPAAPVGAEAVAAPWGEEPAAAWPAPVSPAPEAPAPPPPPPSYPPAGYGPP
                     QGASPAGAVPTAMPAAPVTPAAPVAPVAPVAPATVVSPPPAPAAPGVCPSCAGCGGTCG
                     GAGGHPSGSVGHAPSAVPAPGKPLIYAIGTIGFDFQTEARRDSFRQLMPYVPTDAASGQ
                     PERETQPNIYDPQQLHAYLSKNPWASDKLTWTLNMDATPIYALEAEMPVGMDWTRPIIS
                     DPKATPETVEKLAVGAAQQSGEKSDDGGTPGLLAQILETLAYPPVSRVYRTFRDALLGQ
                     AKNKSDDGYISRVSIPGILTDRTVRLFSGEVLPVVEVKSRGLYTWNETLLVNAVYAAVV
                     ARRVRDARRQAAEDSKKQNLTQDASDAAERAAEARVRDEFADRKGEWLKTTIRALLDKI
                     YWKFRNLGRSSADRALNAAGTNAFMVGAEIQDGILSAGQVPGVSDNFYSLDTVSVAPSP
                     FCRTGSDCQDVVLTFFDPENDRRAPVSYLFTYDVSDEVPVSLAPVHTFIGGM"
     gene            12953..13660
                     /locus_tag="HHL19_RS15035"
                     /old_locus_tag="HHL19_15040"
     CDS             12953..13660
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="HHL19_RS15035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15040"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_169089654.1"
                     /transl_table=11
                     /translation="MSQRARLELLRPLQITCGGRRVTVSAAAQRLLAFLALHRDGVHRR
                     DAAEQLWPDCTPCRAAANLRSALCQGRRLATTPAIDSVDHTLALAPSLAVDFHEAWDAA
                     RLVVSGGEPPSDTDRLVLALGQVLLPGWDDEWLHLERERWDQSRLYALEALAQHFQAEG
                     RHLPALQASLTAAAIDPYRETPQRIAVEVHLAEGNLACAVKRYQDYRRLLQAELKVAPS
                     PRLTRLVRDLTRT"
     gene            13842..14690
                     /locus_tag="HHL19_RS15040"
                     /old_locus_tag="HHL19_15045"
     CDS             13842..14690
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207: inositol monophosphatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737944.1"
                     /locus_tag="HHL19_RS15040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15045"
                     /product="inositol monophosphatase family protein"
                     /protein_id="WP_169089656.1"
                     /transl_table=11
                     /translation="MIESFLEHVLDGGTTEVEEAVRKAVAAEVMPRFRQLADHEIVEKK
                     GPYDLVTVADRAAEERLTEALTALLPGSAVVGEEAVHADPGLYDALRGDAPVWIVDPVD
                     GTRQFVQGDPAFCTLVALAHRGELLASWTYAPALGELAVAVRGRGAVLNGERIRSGSPA
                     PGAVLEVATSHPDYTTPEQKRALLGLVAEGVRTRPCGSAGLEYLSIARGALDATAFNWE
                     YAWDHAAGLLLVAEAGGAQTTVAGEPFRITGGNALPFTAARDAATAERIRVLLAGAPAE
                     D"
     gene            14933..16366
                     /locus_tag="HHL19_RS15045"
                     /old_locus_tag="HHL19_15050"
     CDS             14933..16366
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888833.1"
                     /locus_tag="HHL19_RS15045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15050"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_169089658.1"
                     /sec_met_domain="DAO (E-value: 4.9e-10, bitscore: 34.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLLDAVVVGAGPNGLTAAVELARRGHSVAVFEAKETVGGGART
                     EELTLPGFRHDPCSAVHPLGAASPVFRTMPLDRYGLEWLHPELPMAHPWDDGTAAVLSH
                     SVAETAASLGPRDAGAYRRLVTPFLARWETLFRDFMQLPLTALPRDPAGLARFGLAGLP
                     PSTWLLRRFRDEKARALFAGMVGHVIAPLDGFATSAVGLVFALAAHAVGWPVPRGGSQA
                     IPDALTAYLAELGGTVHTGYEVKRLDDLPPARAYLFDTSPTALARITGFGAHHYAHYKY
                     GASAFKIDYALDGPVPWTAEAARRAGTVQVGPTARAIDTALRQASSGSAPEAPFLITAQ
                     PSLVDPSRAPEGKHVFWAYGHVPNGWRGDLTDAMERQIERFAPGFRDRILARATAGPPE
                     LAARNANYIGGDIACGAARGLQLVLRPTLSPWPYRTPHPSVFLCSAATPPGPGVHGMSG
                     HNAAKAVWRHLRSLDGQGT"
     gene            16376..16996
                     /locus_tag="HHL19_RS15050"
                     /old_locus_tag="HHL19_15055"
     CDS             16376..16996
                     /EC_number="2.7.7.87"
                     /GO_function="GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004004059.1"
                     /locus_tag="HHL19_RS15050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15055"
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="WP_169089660.1"
                     /transl_table=11
                     /translation="MAKYIDVHPQNPQPRIIDGVADSIRKGGLIAYPTDSCYALGSRIG
                     NHEGLTRIREIRRLDDRHHFTLMCADFAQLGQLVHIDNRVFRAVKSAVPGAYTFILPAT
                     KEVPRQLLHPKKKTVGVRIPDHVVTQALLASLGEPLLSSTLLLPDEEEPLTQGWEIKER
                     LDHQVDAVLDSGDCGTVPTTVVDFSEGDPEVLRVGAGDPTRFE"
     gene            17134..17931
                     /locus_tag="HHL19_RS15055"
                     /old_locus_tag="HHL19_15060"
     CDS             17134..17931
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836518.1"
                     /locus_tag="HHL19_RS15055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15060"
                     /product="metallophosphoesterase"
                     /protein_id="WP_169089662.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.5e-09, bitscore:
                     33.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVIAHVSDIHIDAEERATARTRAVLRHLEELPYDLAAVLVSGDI
                     ADHGAPAEYDGARALLAGRHPLVVCPGNHDDRAAFRAGLAPLLHEDGDPAPTAPVDQVL
                     RGDGFVLAVCDSSIPGKHDGYLEDTTLEWLDRVLTDTPYDTPVLVAFHHPPVPLHTPYV
                     DEIRQYGEDRLAALAARHPHLTAFLAGHAHTAAATTFAGRPLLVAPGTVSTLRLPWEHP
                     GPERPHVHLDTPPGVAFHVLDDEGRVTTHFRTVPVSGRRSLSS"
     misc_feature    17938..17954
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.49"
                     /tool="antismash"
     gene            17988..19457
                     /locus_tag="HHL19_RS15060"
                     /old_locus_tag="HHL19_15065"
     CDS             17988..19457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003954508.1"
                     /locus_tag="HHL19_RS15060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15065"
                     /product="AlkA N-terminal domain-containing protein"
                     /protein_id="WP_169089664.1"
                     /transl_table=11
                     /translation="MHTQTERCVRAVQSKDARFDGVFFTAVRTTRVYCRPSCPAVSPKP
                     ENMEFHPSAAACQRAGFRACKRCRPDTSPGSPEWNVRADAVARAVRLIQDGVVDREGVP
                     GLARRLGWSTRQIERQLLAELGAGPLALARAQRAQTARTLVETTALPFGEIAFAAGFSS
                     IRSFNDTVRQVFALSPGELRARAARPAAPHPPGVISLRLPFRAPLEPSNLFGHLAATAV
                     PGVEEWRDGAYRRTLALPYGHGIVALAPRPGHIACRLSLTDTRDLTHAISRCRRLLDLD
                     ADPVAVDDRLRADPLLAPLVEQAPGRRVPGTVDPAEFAVRAVLGQQVSTAAARTHAARL
                     VTAHGVPVEDPEGGLTHLFPTAGALAGLDPETLALPRSRRTTLLTLAGALADGTLSLGP
                     DTDRAETRARLLALPGFGPWTTEIIAMRALGDPDAFLPGDLGVRRAAEGLGLPATPGAL
                     TARSTAWAPWRAYAVQYLWATDSHPINHLPA"
     gene            19470..20003
                     /locus_tag="HHL19_RS15065"
                     /old_locus_tag="HHL19_15070"
     CDS             19470..20003
                     /EC_number="2.1.1.63"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037467.1"
                     /locus_tag="HHL19_RS15065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15070"
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="WP_169089666.1"
                     /transl_table=11
                     /translation="MPRTAAYRAATHRTVVHTVVDSPYEPLTLVAVDGVLSRVHMTGQR
                     HRPPEETFGARDPRPFGEAIRQLDAYFAGELTEFDLPLHLEGTPFQLRVWEQLRLIPYG
                     ETRTYGELAEALGSPNASRAVGLANGKNPVGVIVPCHRVIGSGGSLTGYGGGLDRKQRL
                     LAFESGVAAPDALF"
     gene            complement(20000..20716)
                     /locus_tag="HHL19_RS15070"
                     /old_locus_tag="HHL19_15075"
     CDS             complement(20000..20716)
                     /EC_number="2.3.1.286"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579470.1"
                     /locus_tag="HHL19_RS15070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15075"
                     /product="Sir2 family NAD-dependent protein deacetylase"
                     /protein_id="WP_169089668.1"
                     /transl_table=11
                     /translation="MTMVAILSGAGISTDSGIPDYRGPNGLWRRDPEAERLVTYGPYMA
                     DPEVRRRSWLMRRDAPVLTAEPNAAHRAIAAYERTGNALRVITQNVDGLHQAAGVPDRK
                     VFELHGTARRVVCTACHARSPMAEALERLEAGDPDPACRACGGILKPATVMFGQRLDPV
                     VLANAMSVAKAAEVFVAVGTSLQVQPAASLAGVAAEHGARLIIVNAEPTPYDPLAAEVL
                     REPIGTALPALLDRLA"
     gene            20780..20983
                     /locus_tag="HHL19_RS15075"
                     /old_locus_tag="HHL19_15080"
     CDS             20780..20983
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018519878.1"
                     /locus_tag="HHL19_RS15075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15080"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_169089670.1"
                     /transl_table=11
                     /translation="MAKVNIALDADLVVEVMVLAGVGSPQDAVEAVVRDYIARGHRTEA
                     RTATREEVNRTGEMLPPEPPQG"
     misc_feature    20820..20834
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            20980..21177
                     /locus_tag="HHL19_RS15080"
                     /old_locus_tag="HHL19_15085"
     CDS             20980..21177
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HHL19_RS15080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HHL19_15085"
                     /product="hypothetical protein"
                     /protein_id="WP_169089672.1"
                     /transl_table=11
                     /translation="MSPPAAPDPDPDSDRRARLLIGDCFGAVVAGILPTVVAMLLMSVA
                     ITGFSDRDGGDSRPVPTAAS"
     gene            complement(21215..21712)
                     /locus_tag="HHL19_RS15085"
                     /old_locus_tag="HHL19_15090"
     CDS             complement(21215..21712)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656736.1"
                     /locus_tag="HHL19_RS15085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HHL19_15090"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_169089674.1"
                     /transl_table=11
                     /translation="MTVTDYATCIAGLPRVLAGAAVLFRDARGRILVVEPGYREGWVLP
                     GGTVESDAGETPRQAARRETLEEIGLDVPPGPLIAVDWSQSPARPPVVAYLYDGGVLPE
                     ERFAEIRLQEAELLSWKLIEPSEIPAHLPGSLGPRVLAGLRALADGSGPAELVNGLRSD
                     EA"
ORIGIN
        1 tcgccaccct cgccgggttc tcgctgatgc tgatcgccgg ccgtcgtgag ccgaagaccg
       61 gcctggccgg ccggcaggcg aaggcccgga tcgcgatccg cgccgtggta ctgctggccc
      121 tgggcagcgt gctggcgatc gaatacgggg acgtcatcat cctcggcttc tacggcgtct
      181 acttcctcct cgccctgccc ctgctgcggc tgtccgccag gacactggcg atcaccgccg
      241 cgggcctcgc gctcgtcgca ccccagttgg cgttcgtcct gcgcacgtgg ctgggcgaat
      301 cggtccagca gagcatcaac gcctacgatc cgctcgagaa gctcaacggc gtgggagtga
      361 tcgatctgct gctcacgggc ctctatccga cgatcacgtg gatgccgttc gtgatcgccg
      421 gtatggcatt ggcccgcctc gacctgtcgg ccgtctccgt ccagcggcgc ctggccgccc
      481 tcggcgccgc cctgaccgtg gccgcgtacg gtctgtcgct gctgctggcg ggcaaggacg
      541 cggtgttcgg gggaaccggt gggtcgtccg ccggctccgg gtcctggtcc ggcggctccg
      601 gggccgcttt cagcggttcc gggtcggggt ccggcggcag cggctccagc gagcagctcg
      661 tgtcgtctgc cgcggacctc ctgggtgccg gcccgcacac cggcaccacg ttcgacatca
      721 tcggcagcgc gggcgtcgcc atcctcgtga tcgtgggcgc gacggtgctg atggaccggg
      781 cggcgcgcct gcgccgtctg gcgaagccgg tcatcgccgt gggcaccatg tccctgacgg
      841 cctatgtcgg tcacttcctc gcacagtccg cgtggcccgc ttccggctcc ggcaccacga
      901 agtcctgggt gcccgtgctc acgtacatcc tgtgcgcgat cgtgttcgcc gcggtgtggt
      961 cccgcttctt ccgccgcgga ccgctggagg cgctgctcaa cgccgccacc gagccggcga
     1021 agtacgtgcg atgacgggac cggggcgggc ggcctctcct ggcccgcccc ggctccgacg
     1081 gccctcgcgg cccgctcaca tcgaccgtcc gtccggcacc ccgcccgaac ggctgaagca
     1141 ggccccgagc ggctcggaca ggtacgtgtc gtcgctccgg aaccggaatc cacatgacct
     1201 tcgtcctgat cgtgatcacc gcagtgacgg ccgggtgggc gctcgtcgcc cggaggcttg
     1261 agcgggggca tgtcagagcc cccgtggtgc tggtcctcgc gggcgtcgtc accggggtgt
     1321 tcacgcacag ccggatcgcg gtcacgctca actccgagat cgcccagcac gtggccgagg
     1381 tcatcctggc ggtcctgctg ttcgtcgacg cgacggaact gccgggtggc cggctgttcg
     1441 gcaacgaccc cggcgaggcc gcccgcaccc tgctcgtggc gctgcccctg agcctggccg
     1501 ccgtcgtcct gctcggcacg ctgctgctcc ccggcctgcc cgcggtgatc ctcctgatca
     1561 tcgcgggcat catcgtcccg accgacttcg ccccggccga gaccctcgta cgggacaccc
     1621 gcatcgcggc gcgcgtccgc gacgtcctca acgtggagag cggctacacc gacggcatca
     1681 tctcgcccgt cttcctcttc gcactcatcc tggcgggctc cacctcacag gcgcacactc
     1741 ccgtgcaggc actggccacg gccgttccgt tcgccgcgaa ggccctggcc gtgggcgtcg
     1801 ccctcggttc cctgctcgca tggctgatga ccacggccga ccgcaggcag tggatgaccg
     1861 gacaatcccg ccgcgtcctc gtcctggtca caccgctgct cgtccacacc gtgacggtgg
     1921 cggccggcgg caacggcttc gtcgccgcgt tcgtctgcgg catcgccttc cggtacgtcc
     1981 ggcagacccc ggcccggcga cacgagtcct acgtccccga cgcttcggac ttccgcctcg
     2041 tcgaggacac cggctcgatc atggccatgt gcatgtggtt cttcttcggc aacgccaccg
     2101 tgctcgccct gagcgagggc atcgacgtgc cgaccgtgct gctctgcctc gccgcgctca
     2161 ccgtcgtacg cgtcggtccg atcctgttcg ccttcctcgg ctcggccttc accgggcgtg
     2221 aacggctcat gatcgggacc ctcggcccac gcggcaccac atcgatcgtg ttcggcctgc
     2281 tcgccttcaa cgccctcccc gacggcccct ccgcggacac cgccctgtac gccatgaccg
     2341 tcaccgtgct cggcagtgcc ctgctccatg gcctcggctc gacgcccctc gcccgcctgc
     2401 tcaccgcccc tgcccccgcc cccactcccg cccccgtccc cgcctccccg gccggcccgg
     2461 agaaggtccg ctgagcacgt gggcggccac gcttctcacc cgacggggcg ccccgccggg
     2521 gtcaggaact gggtcgcggc gagctgtgcg tacagctcgt cctcggccac cagctcctcg
     2581 tgggtgccga tcgcgcggac cgtgccggcg tccatgacga cgatgcggtc ggcgtccgtc
     2641 accgtggaca ggcggtgcgc caccaccagg acggtggtct cgcgcgccgt ctcgccgatg
     2701 acgtcccgca gcgccagctc gttcaccgcg tcgagctgcg aggtcgcctc gtcgaggagc
     2761 agcagccggg gcttgcgcag cagtgcgcgg gcgatcgcga cgcgctggcg ctcgccgccg
     2821 gacagcttcg agccgcggtg cccgaccggg gtgtccaggc cgtgcgggag acgctcgacg
     2881 agggtgtcga gcctggtccg ggcgaggacg gcgcggatgt cgtcgtccgt cgcgccgggc
     2941 gcgctgaaga ccaggttctc ccgcagcgtg ccggccagaa ccggtgcgtc ctgctcgacg
     3001 tacccgatgg cggaccgcaa cgcggacagc ggccactgcc ggatgtccgt accgtcgacc
     3061 aggacgcgcc cgccggtcgt ctcgtagaac cgctcgatga gcgagaagac cgtcgacttg
     3121 cccgcgcccg aaggcccgac gaaggcggtc agcccggcgc ccggcacctc gaagtccacc
     3181 cgctggtgga tgtacggcag cccgggcccg taccggaagg acacgtcctc gaagcggacg
     3241 gacgccggac gcgcctcggt ccgcaccggc tcgtacgtgg ccggcggctc cgccgccagg
     3301 cggtcgacct ccttgatccg ggagatcgcg gccgcgccct cctggtacgc ggaggcggcc
     3361 tcgaccagct tgtacaccgg ctccatcagg tagaacaggt acagcaggaa ggcgatgagc
     3421 gtggagacgg ggatgtcccc ggacgccacc ctcgctccgc cgaccgcgag caccgcgagg
     3481 aacgccagct cgacggcgag gttgtccgcc gtccccagca gggcctccca cttcgcgccg
     3541 cgcacgccgt ggcgccacgc ccgccgggcc gacgcctcga cgcgggcggt ctcccgctcc
     3601 tcggcaccgg acgccttcac cgtgcggaac gcgccgaaga cccgctccag gccggtggac
     3661 atctccccga cggcggcctg ggagcgctcg gcggcccgcc cgatcctcgg catcaccagg
     3721 gcggcgcccg cgccgacgac cacgaccaca ccgagcgtga cgccgagcag gacgacgtcg
     3781 aggaaggcca tcaccacgac cgccgcgatc agcgtcagcg ccccggtcgc ggcgttgacc
     3841 accgcctggg tgctgaccgc ccgcagcagc gtggtgtcgg aggtcacccg ggccatcagg
     3901 tcgcccggct gcgtccggtc caccgccgag agccgcagcc gcagcatccg gccgatcagg
     3961 ctgcggcgag cggccaggac caccgactcc gccgtccgct ccagcacata cgcgccgaac
     4021 gcctcggcca ccgtgctcag cagcaccagt acggtcagcg ccagcaggac ggcggcgagc
     4081 gtgccgccgg acgagagccg gtcgaccagc tccttcgtgg ccagcggctg cagcagcccg
     4141 ccggcggcgc ccaccagcgc cagcagcaga ccgagcacga ccgcccaccg gtgcgggcgg
     4201 acgtacccgt acagcgcctt gagcgtctcg cggacgcgca gggactcggc acccgtcgtc
     4261 tccggggcgg atgcggtgtt cacaggattc cttccctcgg tggtccgccg ctgcgccagg
     4321 ggacgcgccg aagcggcgcg ctcctgccgg gtgtgcggcg tgtgatgcca ccagcgtgga
     4381 agcccggaga cctctcgggc tatccggcga tcgtcgggag gacccccgcc gagtggccgg
     4441 aacccttgag ggcaccatcg acgcagaggc gaccaggggc gaccaggtgc ggccaggtgc
     4501 ggcctggtgc gactagagcg agtcgagtcc gcgttcgtgg cggtccacgg cctcgcggac
     4561 ggcgtcgacg aagccgttcc agaagtgggc ctcgtgggcc gtgcccacgc cggcgctcgt
     4621 ccggcggccg gaggcgccgg agaagtcgcc gaacatcgcc ctgcggagct cggtggagat
     4681 ctccagctgc gcgccggcgc cggtgcgggt gcggttgacg atgttgtccg ggtcgtcgcc
     4741 gttcaggggg ctgttcacac ccgcgacggt gaccgtcacg tcgagcgccg ggtcggcgtt
     4801 gccggtggtg agcccgtggc cggcgaaggc cgcggcgagg ttccgcatca ggcgcgtgtc
     4861 ccggccgccg atgaggatct gcttggccgg cgtgcccgcg tccggcgcga agccgtgcag
     4921 ggagacggcg tacaggttgg cggcgcagac cgccagggcg gcggggtcgt cgcagtgggt
     4981 cgacgtgacg tggagggagc tggaggacgc gatgccctcg aacatccagt agtcgcgctg
     5041 cggcacggcg ctgtccgcca ccgggtcggt cccggcgccg acgcgcgagt atccggcgag
     5101 ggtgaggcag agctcgctgg tacccggctc gatgccgccg ccgtgcggcg cgatgaccgc
     5161 cgtgctgcgt atgacgctgc tgctcgcgct cgcgttgtcg aggaggaggc cctgggcgtg
     5221 ggtgcggaag cgccgcatcc agtggacgcc ctcccggtac tcggtgctgc tgtacagcgc
     5281 cgcgttcgtc gggaactcgg tcgcggtggt cgccgcggcg gcggtgccgc cgttcccggc
     5341 gaggtcgttg agcaggggca gggaggccgc cgccgcggcg acggaggtca ggagcgtacg
     5401 tctgctggtg agcgtcatga gccgatcatc ccagcagccc acgggagctc cggcagccca
     5461 cgggcgctgc ggctgcccct gccgtccccg gcaccgccct cctcctctgc acgggcctca
     5521 tgggacgccg tcgtcggagt gacgccccgg cgcggcaggg cggcggggcg gggccggctg
     5581 cctagggtcg gtcgcacgtc tggaccccct cggctcggag aggagccccc gtggcctcac
     5641 ggctcaaccc ctacctcagc ttcaccggct cggcgaagca ggccctcgac ttctaccagg
     5701 acgtcttcgg cggcgagccc gtcgtcaaca cctactccca gttcggcgag gcgccccccg
     5761 gcttcgcgga caagatcatg cacggcatgc tggagacccc ggcgggcttc acgctgatgg
     5821 tctcggacac cccgcccggc atggaccaca cccccggctc caccatcagc atcagcgtca
     5881 gcggcgacga cgaggccgaa ctccgcggct actgggagaa gctctccgcg cgcggcacgg
     5941 tctccgtccc cctggagaag cagatgtggg gcgacgtctt cggcatgtgc accgacgagt
     6001 tcggcgtcgt ctggatggtg gacatcaccg ccgaaccctc ctgaccggtc tgaccaccgg
     6061 aaacgtgggt gagaagcacc tcgaacacct ggtagattga tgttcgtcgc cgcgagggaa
     6121 accagcggag accaacacct tgtccgggtg gcggaatggc agacgcgcta gcttgaggtg
     6181 ctagtgccct ttatcgggcg tgggggttca agtcccccct cggacacgat cgacgacgag
     6241 ccgtgcgggc cggtggaaac cggaccgcac ggctcgttct cgtacgcccg gacgtcctca
     6301 ggccgccggc gggcggacgc ccgtcgtgcg ggcgatccac gccaggtggg aggtgatcct
     6361 ggtgttcacc gcaggggtgt ccgtggcgca gccgcggccg taggagacga gagcagccag
     6421 gacggggcgg cccgttccgg tgcggtgcga cagggggccg ccggagtcgt agacgcaggt
     6481 gtcgcggccg ggggtccagg tgcagagctg ggccggggtg agggggccca cgtcccggcg
     6541 ggcgcacgcg gcgtggggga cggtgtcgag ggtgaccgtg cgcaggacgg gggaggggcc
     6601 ctcgccgaag gcggtcgcgc cccagccgac ggcttccaga cgcgtgtggt cgaacgtttc
     6661 ggcaggtgtg gggagcgcga tcgggcgcac gccggcgtcc gggcggaccg gatccgacag
     6721 ggtgatcacg gcgaggtcgt cgtgctgggt gcgggagtcg tagccggggt ggacggtgaa
     6781 gcggacggga cgggccacgc gcgcgtgccg ggactccgtc gccgtgcgca ggtcgtggtc
     6841 gccgaggagc accgcgaccc ggcgggtgtc cgcgtacgag ccgctcaggc agtgcgcggc
     6901 cgtcaggacg tgccgggtgc cgatcagcgc gccgccgcag aactggcggt gccgctccac
     6961 gtcgaccagc gccgccacgt aggggtacgc ccccggggcc gcctcctgcc cgccgaccac
     7021 ggccgccgcc tcgcgaggcg cgcccggcat cacccccagg accagccccg cgagcgccgc
     7081 cgctaccgtc ctcacccgtc ccaaggtgcc ctccatgacg tcgacccagc gtgtccatga
     7141 cgtcaacgag ccgacgacgg gcaggtcacc gctccgcgtc gggccgccgg ccggggaggt
     7201 acgcggcggc cgccgcctcc caggcccgga caccgcccgg gaagggccag gcgcggctcg
     7261 ggggcggcga tgtcggcgac cgaggccggc tcgcgggcga gcgcgcgggc cgcgttcgcc
     7321 gccgcccgtc gggcgcactc catccgcagc ccggggcgca ccggggatcc cacacgcgtg
     7381 ggagagacgc tacggcaccc gcgcggtcca ctccggggac gagaacttgc cctccgccag
     7441 ctccttggcg gcggccagct cctcctccgt cacccggccc tccgtcaggc cgtagcgctg
     7501 ccggaaggag gcgatcatcc tctcgatcac cgcctcgcgc gacagacccg tctggcggcg
     7561 cagcgggtcg acgcgcttct tcgcgctcct ggtgcccttg tcggagagct tctcgcggcc
     7621 gatccgcagc acctcggtca tcttgtcggc gtcgatgtcg tacgccatcg tcacgtggtg
     7681 cagcaccgcg cccgcgcccg tcaccatccg cttctgcgcc gcgcccgcga tcttcccggc
     7741 ctcggtggcg atgtcgttga gcggctggta ccaggccttc acgcccatgt cgccgagcgc
     7801 gccgaggacc cagtcgtcga ggtaggcgta gctgtcggcg aaggacaggc cctgcaccag
     7861 ggcgtcgggc accgacaggg agtacgtgat ggtgttgccg ggctcgatga acatggcgcc
     7921 gccgccgctg atccggcgca ccacccggat gccgtgccgc tcggcggcct ccgggtccac
     7981 ctcgttgcgc agcgactgga agctgccgat gacgacggcg ggcgcgcccc actcccagac
     8041 ccgcagggtc ggcggccggc ggccgtccgc gacctctgcg gtgatcacct cgtcgagcgc
     8101 catgtgcagg gcgggggact gcggcggctc gtggatcagc tgccagtcgt agtcggtcca
     8161 gtcggtggcg tgggcgagcg cccggcggac ggcgacgccg accccctcgc tggtgaggcc
     8221 gtacatctgc gtgccgggcg gcagggccgc gtcgatacgg gccgcgagcc cggcggcgtc
     8281 ggtgtcggcg ggcgcgccct ccagagcgcg gtcgatggag aggatcgcct cgtcgggttc
     8341 gaggaagaag tccccggcca cccggacgcg acggagtgcc ccgtcctcga cgtccagatc
     8401 gacgacgacg agcttgcccc cgggcgcctt gtactcaccg tgcaccgttt cgtccccttt
     8461 ccacaggtgg tgacgatcct agccagggac gtcccggggc gaacgcgtct ccccggccgt
     8521 cgccctgtcg ggagacggcc ggggagcatc agggtttcct cctagagggg gccgagccag
     8581 gtgcacgcgt cggccccttc acccgagggg cagttccatc cccggtccgc cgcgcccgcc
     8641 cagggcgggt cgttgacgtc ggagccgaag ttggacttgg gcgggggctc ttcgctcacg
     8701 taccccgcca cctctgtgtc cgggtcctcc tcatcggtgc ggtagtagta gacgcgcacg
     8761 tccttcagga agggccggta cgtgtcccag cggcgctcca ccgcgccgag caccggcaga
     8821 ttcggcccgg tgccggcggg cgggggcacc gcctggtgcg tgtcgttcat gctgccgtcc
     8881 tttcaggccc ggccggggcc gcggcaccgc cgcgtgcggc cggcgtacgg cctcacttga
     8941 agaaggcgcc gatcgccttc gtcgccaggg gcagcagcca ggcgaagtcc gcctcgacgc
     9001 cgcccccgtg cccggtgccg gcggcgaggg gggccggccg ggtgcggtcg acggccggtg
     9061 cctggaccgg tgcgcgcacg acggccgccg gggccgcccg tgcggggaag tccttgttca
     9121 tgtccgtgtc ctttccgtgc tctcggaccg gtgagtctgt gctctcggac cggtgagtcc
     9181 gtgttctcgg atcggggagc cgtggggcgc taggcctggc gggagagcca ggcgtccagc
     9241 attcccttgg ctccgtgacc gatcagctgc cagggcacct cccagttcgc ctcggcgccc
     9301 tgcgagcccg cgccggcccg tgccggtgcc gagggggacc ggtcgacggc gggcgtctgg
     9361 aggggaggcc ggggcgccgc cgtgtccggg aattcgctgt tcatcccggt gtcctttcga
     9421 agaggtccgc acagcggtgg ccgggcgcct ggacgcgggc caccgctgcc gcggagggtg
     9481 ctgcgagcgg cccttctaga agaggacctt cttggcgatg ttccagatgt cgcccaggcc
     9541 gaagttggcc tggacgccgt ccgccgcctc accggcgttc gccgggccgg cggggctgcg
     9601 gtcgatggcg ggagtctgga acggcgtctg cggagcgccg gccggagccg gccgctcctc
     9661 gtaccgcgtg aacggctcgt tcatcgttct cacctttcat cgggtgacgg tccggcgagc
     9721 ggttgccgcc ggaggctggt gctgcccggc cggtccgtgc cgccgcgcgc gtgtcacagg
     9781 gcgtaggacc gctgcgcgta gcacatctgc cgggcgggtc cccacaggtc cgcgcagccc
     9841 gagcgggccg cctgaacgcc ctcggcgccc tcggcgccct ggtccggccc ctgccgcggc
     9901 tgccgccacg ggtcacggac gaccggcagg gcctgcggag ggagggaggg ggtgggggag
     9961 gtggtcgtgt ccatgaggag ctcctcggtg ggggcggcgc tcacatgccg ccgatgaagg
    10021 tgtggaccgg agcgaggctg accggcacct cgtcgctcac gtcgtacgtg aacaggtacg
    10081 agaccggagc gcgccggtcg ttctcggggt cgaagaaggt caggacgacg tcctggcagt
    10141 cggacccggt gcggcagaag gggctcgggg cgacactgac ggtgtcgagc gagtagaagt
    10201 tgtcgctgac gccggggacc tgaccggcgg agaggatgcc gtcctggatc tcggcgccga
    10261 ccatgaacgc gttggtgccg gcggcgttga gcgcacggtc ggcggaactg cgcccgaggt
    10321 tgcggaactt ccagtagatc ttgtccagca gggcccggat ggtggtcttg agccactcgc
    10381 ccttccggtc cgcgaactcg tcgcggaccc tcgcctcggc cgccctctcg gccgcatcgg
    10441 acgcgtcctg cgtcaggttc tgcttcttgg agtcctccgc cgcctgccgg cgcgcgtccc
    10501 gtacgcgccg ggcgaccaca gccgcgtata ccgcgttgac cagcagcgtc tcgttccagg
    10561 tgtacagtcc gcggctcttg acctccacca cgggcagcac ctcgcccgag aacagccgga
    10621 cggtgcggtc cgtgaggatc ccgggtatcg agacccgcga gatgtagccg tcgtccgact
    10681 tgttcttggc ctggcccagc agggcgtcac ggaaggtgcg gtagacgcgg gagaccggcg
    10741 ggtaggcgag cgtctccagg atctgggcca gcagccccgg agtgccgccg tcatcgctct
    10801 tctcgccgct ctgctgcgcc gcccccaccg cgagcttctc cacggtctcg ggggtcgcct
    10861 tggggtcgga gatgatgggc cgggtccagt ccatgcccac cggcatctcc gcctccaggg
    10921 cgtagatcgg ggtggcgtcc atgttgagcg tccaggtcag cttgtcggag gcccacgggt
    10981 tcttgctcag gtaggcgtgc agctgctggg ggtcgtagat gttcggctgc gtctcccgct
    11041 ccggctgccc cgacgcggcg tcggtgggga cgtacggcat cagctggcgg aagctgtcgc
    11101 ggcgggcctc ggtctggaag tcgaacccga tggtgccgat cgcgtagatc agcggcttcc
    11161 ccggcgccgg caccgcggac ggggcatgac cgacgctccc gctgggatgt ccgcccgcgc
    11221 ccccgcacgt accgccgcat ccggcgcacg acgggcacac gcccggggcg gccggggcgg
    11281 ggggaggaga gacgaccgtg gcgggtgcga cgggtgcgac aggtgcgaca ggtgcggcgg
    11341 gtgtaacggg tgcggcgggc atggcggtcg gtacggctcc ggccggggac gcgccctgcg
    11401 gcgggccgta cccggccggc gggtacgacg ggggcggggg cgggggcgcg ggtgcctccg
    11461 gcgccgggga caccggagcc ggccacgccg cggccggctc ctccccccag ggagcggcca
    11521 ccgcctcggc gccgacgggt gcggcgggcg cctcctgggg tacggccgcg ggagcggtac
    11581 gggcgtccgc gggcaggggg tcgggaggct gggcgacctg cgggtgtacg gcgttcgtgt
    11641 ccatgacgat gactctttct ctcggtccgg cgggggaggc cccggcggcg accggggcgg
    11701 gtgcgccgtc cccgtcgacc agggcgaagg cgccgggggc gttcagcagg ccgcggagca
    11761 gcctgcggca ctcgggggcg tcgtcggggt cgcagggcgg ccggagcgcc gactccagga
    11821 cggcccggcc ggccgcgatg gggtcggccg cgtgtccggt ggccagctgc ctcgccacca
    11881 gcagggccac gactccggtg accgccgggg cggcgaagct gctgccggtg agcgaggcga
    11941 acccgccgcc gggggcggcc ccccggatgt cccggcccgg cgccactacg ccgttcagcc
    12001 ggtaggcgcc gccccagttg ttgatgccga gcggcgcgcc ggtggcgtcg gcggctccca
    12061 cggcgaggac ggacggcgtg gcggcgggcg cctgcaggca gtcgcacccg tcgttcccga
    12121 cggcggcgac caccaggacg cctcggtccg cgcagaggcg gagggcccgt tcgagcatgc
    12181 tgttcggcgt gcccgcgggg gtccgttccc caccgctgac gttgacgacg tgggctccgg
    12241 cctccacggc ctgctcgacg gcccgggcca ggtccaactg gggcacacgg gtcacccgcc
    12301 cgtccgggga ctcccggaag accggcagca gcagcccggt gcagcggggc acgaggcccg
    12361 tcatgcccga ggccggctgc ccgaagagca ggctcgtgac gtgggtgccg tgcagcgaca
    12421 tcggcccggt cccggccggt tcggacacca gcgtgggcag acgggtcagg tccgcgcccg
    12481 cgaggcaggg gtgggccagg tccacgggac cgtcgagcac cgccacgcgc acctcggggc
    12541 ttcccaggag ctcgcctcgt ccggcgactc cgcgtaccac cgaccggatg tccatcctga
    12601 acctccgcga tccggggcat cccggcgtgg ggccgggatg gttccctcgt ggcccggtcc
    12661 gctcccgtag cgccgtacgc gtcccgtacc gccgtacgcg gcattccgtg ccacaacgga
    12721 cgttgtccca cacgcctgtt gcggcggcgt cgccctctcc ggcggggcgc gtgcggcgga
    12781 gcgttcccgc aacgtgcggc ccgtgtcgcg ccacgcgtag gagaaacgtt tctgcgtcgt
    12841 gagcgcgccg ttcggcacgg ccgacggggc cggttcggac gcaccgtggg acgcaacggg
    12901 cccgcacgcg caccggttgc agccccccag gccctcgcgc acagtgaaag gcgtgtcgca
    12961 acgagcacga ctggaactcc tgcgccccct ccaaatcacc tgcggggggc ggcgcgtcac
    13021 cgtctccgcc gcggcgcagc ggctgctggc cttcctggcc ctgcaccgcg acggcgtcca
    13081 ccggcgcgac gcggccgaac agctgtggcc cgactgcacc ccctgccggg cggccgcgaa
    13141 cctgcggtcc gcgctctgcc agggcagaag actcgcgacg acacccgcca tcgacagcgt
    13201 cgaccacacc ctcgccctcg cgccctccct cgccgtcgac ttccacgagg cctgggacgc
    13261 cgcgcgtctg gtcgtctccg gcggcgaacc gccgtccgac accgaccggc tcgtcctcgc
    13321 cctcggccag gtcctgctgc cgggctggga cgacgaatgg ctccacctcg aacgcgaacg
    13381 ctgggaccag tcgcggctgt acgccctgga ggccctcgcc cagcacttcc aggcggaagg
    13441 ccgccacctg cccgccctgc aggcctcgct gaccgccgcc gccatcgacc cgtaccgcga
    13501 gaccccgcag cgcatcgccg tcgaggtcca cctggcggag ggcaacctcg cctgcgccgt
    13561 caagcgctac caggactacc gccgcctgct ccaggcggag ttgaaggtcg ccccgtcccc
    13621 ccggctgacc cgcctcgtcc gcgacctgac gagaacctag cgcgcactcg acctgtcggt
    13681 gggtcgtcct catggaggcc gagacctgcc ccggttgcga ggaccgcccg gcagtcggcc
    13741 gtacgggccc ggaccgcgag tcgccaccgc gtccccccgt gaacctcggc tgcggggcag
    13801 gccccgtacc ggttgtcgga cccgcgtgct tagctggacg catgatcgag tccttccttg
    13861 agcacgtcct cgacggtggt acgacggagg tggaggaggc ggtccgcaag gcggtcgcgg
    13921 cggaggtcat gccgcggttc cggcagctcg ccgaccacga gatcgtcgag aagaaggggc
    13981 cgtacgacct ggtgacggtc gccgaccggg cggccgagga gcgtctgacc gaggcactga
    14041 ccgcgctgct gccgggctcc gccgtggtcg gcgaggaggc cgtccacgcc gaccccgggc
    14101 tgtacgacgc gctgcgcggc gacgcgccgg tctggatcgt cgacccggtg gacggcaccc
    14161 gccagttcgt ccagggcgac ccggccttct gcaccctggt cgccctcgcc caccgcggcg
    14221 agctcctcgc ctcctggacc tacgcgcccg cgctcggcga gctggccgtc gccgtgcggg
    14281 ggcgcggagc ggtgctcaac ggggagcgga tccggtccgg ttcgcccgcc cccggcgccg
    14341 tcctggaggt ggccacctcg caccccgact acaccacgcc cgagcagaag cgggccctcc
    14401 tcgggctcgt cgccgagggc gtcaggaccc ggccgtgcgg ctcggccggc ctggagtacc
    14461 tgtcgatcgc ccggggcgcg ctcgacgcca ccgccttcaa ctgggagtac gcctgggacc
    14521 acgcggccgg gctgctgctc gtggcggagg cgggcggcgc gcagacgacc gtcgccggcg
    14581 agccgttccg gatcaccggg ggcaacgcgc tgccgttcac ggccgcacgg gacgccgcca
    14641 ccgccgagcg gatccgcgtc ctcctcgccg gcgccccggc cgaggactga cggatgctca
    14701 cgagggccgc ccggcagggg agccggccgt ctccgaatcc cggccgccgc ttcggccggc
    14761 cgcggaaccg gtccttcccg cacccgggcc acgtcggacg gttgcggaac cggtccttcc
    14821 cgcacccggg gcgccacacc ggtcccatgg gtcccgaggg gccgccgcgc cgcccgggcg
    14881 ggcgggccta tcctggccct gccgaagcgc cggccgacgt gaggagcccg aggtgacgtc
    14941 actgctcgac gccgtcgtcg tgggggcggg gcccaacgga ctgactgccg ccgtggagct
    15001 ggcccgccgc ggccactccg tggccgtgtt cgaggcgaag gagaccgtcg gcggcggagc
    15061 ccgcaccgag gagctgaccc tccccggctt ccgccacgac ccctgctccg ccgtccaccc
    15121 gctgggtgcc gcctcgcccg tcttccggac catgccgctc gaccggtacg gcctggagtg
    15181 gctccacccc gaactgccca tggcccaccc gtgggacgac ggcaccgccg ccgtcctctc
    15241 ccactccgtc gccgagaccg ccgcctccct cggaccgcgc gacgccggcg cctaccgacg
    15301 gctcgtcacc cccttcctcg cccggtggga gacgctcttc cgggacttca tgcagctgcc
    15361 gctcaccgcg ctgccccgcg acccggccgg cctcgcccgc ttcggcctcg ccggactgcc
    15421 gccgtccacc tggctgctgc gccgcttccg cgacgagaag gcccgcgccc tcttcgccgg
    15481 gatggtcggc cacgtcatcg ctccgctcga cggcttcgcc acctccgccg tcggcctggt
    15541 cttcgcgctc gccgcgcacg ccgtcggctg gcccgtgccc cgcggcggct cccaggcgat
    15601 cccggacgcc ctcaccgcgt acctcgccga gctcggcggc accgtccaca ccggctacga
    15661 ggtcaagcgc ctcgacgacc tgccgcccgc ccgcgcctac ctcttcgaca cctcgcccac
    15721 cgccctcgcc cgcatcaccg gcttcggcgc ccaccactac gcccactaca agtacggtgc
    15781 ctctgccttc aagatcgact acgccctcga cgggcccgtg ccctggaccg ccgaggccgc
    15841 ccgccgggcc ggcaccgtcc aggtcgggcc caccgcccgc gccatcgaca ccgccctgcg
    15901 ccaggcctcc tccggctccg cccccgaggc gccgttcctc atcaccgccc agcccagcct
    15961 cgtcgacccc tcccgcgccc ccgagggcaa gcacgtcttc tgggcgtacg gccatgtgcc
    16021 caacggctgg cgcggcgacc tcaccgacgc catggagcgg cagatcgagc gcttcgcccc
    16081 cggcttccgc gaccggatcc tcgcccgcgc caccgccgga ccgcccgaac tcgccgcgcg
    16141 caacgccaac tacatcggcg gcgacatcgc ctgcggcgcc gcccgcggcc tccaactcgt
    16201 gctgcgcccc accctctccc cgtggccgta ccgcaccccc cacccgtcgg tcttcctctg
    16261 ctccgccgcc accccgccgg gccccggcgt ccacggcatg tccgggcaca acgccgccaa
    16321 agccgtctgg cgccacctca gatccctcga cggccaggga acctagactc gctccatggc
    16381 gaagtacatc gacgtgcacc cccagaaccc gcagccgcgc atcatcgacg gcgtggcaga
    16441 ctcgatccgc aagggcgggc tcatcgccta ccccaccgac tcctgctacg ccctcggcag
    16501 ccggatcggc aaccacgagg gcctcacccg catccgggag atccgccgcc tcgacgaccg
    16561 gcaccacttc accctcatgt gcgcggactt cgcccagctg gggcagctcg tgcacatcga
    16621 caaccgggtc ttccgcgccg tcaagtccgc cgtccccggc gcgtacacct tcatcctgcc
    16681 cgccaccaag gaggtgcccc gccagctcct ccaccccaag aagaagaccg tcggcgtccg
    16741 gatccccgac cacgtcgtca cccaggcgct gctcgcgtca ctcggcgaac ccctgctctc
    16801 cagcaccctc ctgctgcccg acgaggagga gccgctcacc cagggctggg agatcaagga
    16861 gcggctcgac caccaggtcg acgccgtcct cgactccggg gactgcggca ccgtccccac
    16921 caccgtcgtc gacttctccg agggcgaccc cgaggtcctc cgcgtcggcg ccggggaccc
    16981 cacccgcttc gagtgagcgg aaagcggaag cggaaggcgg aagcggaagg cggaaaggcc
    17041 gcctcacccc tagcggccct tacgtccccg tcgtgatcac cgtacggtcg gtcgggtgaa
    17101 ccaccgttca ccccgaccgt cggaggccta cgcgtgatcg tcatcgccca cgtcagcgac
    17161 atccacatcg acgcggagga gcgcgccacc gcgcgcaccc gcgccgtcct gcgccacctg
    17221 gaggagctcc cgtacgacct ggcggccgtc ctcgtctccg gcgacatcgc cgaccacggc
    17281 gcccccgccg agtacgacgg cgcccgcgcc ctcctcgccg gccgccaccc gctcgtcgtc
    17341 tgccccggca accacgacga ccgcgccgcc ttccgggccg gtctcgcgcc gctgctccac
    17401 gaggacggcg acccggcgcc caccgccccc gtcgaccagg tgctgcgcgg cgacggcttc
    17461 gtcctcgccg tctgcgactc ctcgatcccc ggcaagcacg acgggtacct ggaggacacc
    17521 accctggagt ggctggaccg ggtcctcacc gacaccccgt acgacacgcc cgtcctcgtc
    17581 gccttccacc acccgccggt gccgctgcac accccgtacg tcgacgagat ccggcagtac
    17641 ggcgaggacc ggctggccgc gctcgccgcc cgccaccccc acctcaccgc cttcctcgcg
    17701 ggccacgcgc acaccgccgc cgccaccacc ttcgccggcc ggccgctgct cgtcgccccc
    17761 ggtacggtct ccacgctgcg gctgccgtgg gagcaccccg gccccgaaag gccgcacgtc
    17821 cacctggaca ccccgcccgg ggtcgccttc cacgtcctcg acgacgaggg ccgcgtcacc
    17881 acccacttcc ggacggtgcc ggtctccggc cgaaggtccc tgtcgtcctg aaggtccatg
    17941 tcgtttttct gccagcccgg ggcccgcgca tcctcgatcc tggatccatg cacacccaga
    18001 ccgagcgctg tgtgcgggcc gtccagtcca aggacgcccg cttcgacggc gtcttcttca
    18061 ccgccgtccg caccacccgg gtctactgcc gccccagctg cccggccgtc tcgcccaagc
    18121 ccgagaacat ggagttccat cccagtgccg ccgcctgcca gcgggccggc ttccgggcct
    18181 gcaagcggtg ccgccccgac accagccccg gctccccgga gtggaacgtg cgggccgacg
    18241 ccgtcgcccg cgccgtccgc ctgatccagg acggcgtcgt cgaccgggaa ggcgtccccg
    18301 ggctcgcccg gcggctcggc tggtccaccc ggcagatcga gcgccagctc ctcgccgagc
    18361 tgggcgcggg cccgctcgcc ctggcccgcg cccagcgagc ccagaccgcc cgcaccctcg
    18421 tcgagacgac ggcgctgccc ttcggcgaga tcgccttcgc cgccggcttc tcctccatcc
    18481 gctccttcaa cgacaccgtc cgccaggtct tcgccctcag ccccggcgaa ctgcgcgccc
    18541 gcgccgcccg gcccgccgcg ccccacccgc ccggcgtgat cagcctccgg ctgcccttcc
    18601 gcgccccgct ggagccgtcg aacctcttcg gccacctcgc cgcgaccgcc gtccccggcg
    18661 tcgaggagtg gcgcgacggc gcctaccgcc gcaccctcgc cctcccgtac gggcacggga
    18721 tcgtcgccct cgccccgcgc cccggccaca tcgcctgccg gctctccctc accgacaccc
    18781 gcgacctcac ccacgcgatc agccgctgcc gccgcctcct cgacctcgac gccgaccccg
    18841 tcgccgtcga cgaccggctc cgcgccgacc cgctgctcgc cccgctggtc gagcaggcgc
    18901 ccggacggcg cgtccccggc accgtcgacc ccgccgagtt cgcggtccgg gccgtcctcg
    18961 gccagcaggt ctccacggcc gccgcccgca cccacgcggc ccggctcgtc accgcccacg
    19021 gcgtgcccgt cgaggacccc gagggcggcc tcacgcacct cttcccgacc gccggggcgc
    19081 tcgccgggct cgaccccgag accctcgccc tgccccgcag ccgccgcacc accctgctga
    19141 ccctcgccgg cgcgctcgcc gacggcaccc tctccctcgg ccccgacacc gaccgcgccg
    19201 agacccgcgc ccgactgctc gcgctgcccg gtttcggtcc ctggaccacc gagatcatcg
    19261 ccatgcgcgc gctcggcgac cccgacgcct tcctccccgg cgacctcggc gtccgccgcg
    19321 ccgccgaggg cctcggcctg cccgccaccc ccggcgcgct caccgcccgc tccacggcat
    19381 gggcgccctg gcgcgcgtac gccgtccagt acctgtgggc gaccgacagc caccccatca
    19441 accacctccc cgcgtaagga agttccgcca tgccccgcac agccgcgtac cgcgccgcca
    19501 cgcaccgcac ggtcgtgcac acggtcgtgg acagccccta cgagccgctg accctggtgg
    19561 ccgtcgacgg cgtcctcagc cgcgtccaca tgaccggcca gcgccaccgt ccgcccgagg
    19621 agaccttcgg cgcgcgcgac ccccgcccgt tcggggaggc gatccgccag ctcgacgcct
    19681 acttcgccgg cgagctcacc gagttcgacc tgccgctcca cctggagggc accccgttcc
    19741 agctgcgcgt ctgggaacag ctgcggctca tcccgtacgg ggagacccgc acgtacggcg
    19801 aactcgccga ggccctcggc agcccgaacg cctcccgcgc cgtcggcctc gccaacggca
    19861 agaaccccgt cggcgtcatc gtcccctgcc accgcgtcat cggctccggc ggcagcctca
    19921 ccggctacgg cggcggtctg gaccgcaagc agcggctcct cgccttcgag tcgggcgtcg
    19981 ccgcccccga cgcgctgttc taggccagcc ggtcgagcag cgcggggagc gccgtgccga
    20041 tcggctcgcg caggacctcg gcggcgagcg ggtcgtacgg ggtcggctcg gcgttcacga
    20101 tgatcagccg ggccccgtgc tcggccgcga ccccggccag cgaggccgcc ggctgcacct
    20161 ggaggctcgt gccgaccgcg acgaacacct cggccgcctt ggccaccgac atcgcgttcg
    20221 cgagcaccac cgggtcgagc cgctgcccga acatcacggt cgccggcttc aggatcccgc
    20281 cgcaggcccg gcacgccgga tccgggtcgc ccgcctccag gcgctccagg gcctccgcca
    20341 tcggcgagcg ggcgtggcag gccgtgcaca ccacccggcg ggccgtgccg tgcagttcga
    20401 acaccttccg gtccggcacc ccggcggcct ggtgcaaacc gtccacgttc tgggtgatca
    20461 cccgcagcgc gttcccggtc cgctcgtacg ccgcgatcgc gcggtgcgcc gcgttgggct
    20521 ccgccgtcag gaccggggcg tcgcgccgca tcagccagga gcggcggcgg acctcggggt
    20581 ccgccatgta cggcccgtag gtgaccagcc gttcggcctc ggggtcccgc cgccacaggc
    20641 cgttcggccc ccggtagtcc gggatgcccg agtctgtgga gataccggca ccgctgagga
    20701 tcgcgaccat cgtcatgccg ggagcgtagg cacccggatc ggctcccgcg accgggtttc
    20761 gcggtgctag gttccgtcca tggccaaggt gaacatcgcg ctcgacgccg acctcgtcgt
    20821 ggaagtcatg gtcctggcgg gcgtcggcag cccgcaggac gccgtggagg ccgtcgtccg
    20881 cgactacatc gcgcgcggcc accgcacgga ggcgaggacc gccacccgcg aagaggtgaa
    20941 ccgcaccggc gagatgctgc cgccggagcc cccgcaggga tgagcccccc ggcggccccg
    21001 gacccggatc ccgactccga ccgccgcgcc cggctgctca tcggtgactg cttcggcgcc
    21061 gtcgtcgccg ggatcctgcc gaccgtcgtc gcgatgctgc tgatgtccgt ggcgatcacg
    21121 ggcttctccg accgtgacgg cggcgactcc aggcccgtac ccacggcggc gagctgactc
    21181 cccgtcggac cccgtcggac cccgtcaggc ctcgtcaggc ctcgtcggac cggaggccgt
    21241 tcaccagctc cgccggaccg cttccgtcgg ccagggcgcg cagcccggcc agcacccggg
    21301 ggcccaggct gcccggcaga tgcgcgggga tctcggacgg ctcgatcagc ttccaggaga
    21361 gcagctcggc ctcctggagc cggatctccg cgaaccgctc ctcggggagc accccgccgt
    21421 cgtacaggta cgccaccacc ggcggccggg ccgggctctg cgaccagtcg accgcgatca
    21481 gcggccccgg cggcacgtcc aggccgatct cctccagggt ctcccggcgg gccgcctgcc
    21541 ggggcgtctc gcccgcgtcg gactcgaccg tgccgcccgg caggacccag ccctcgcggt
    21601 agccgggctc cacgacgagg atccggcccc gcgcgtcccg gaagagtacg gcggcaccgg
    21661 ccaggacccg ggggaggccg gcgatgcacg tggcgtaatc ggtgacggtc atggcgtcag
    21721 cgtagccagg cggagcgtcc gctcggcgag ttggcggatg ctcgccccgt cgaagccgta
    21781 caccgcgctg cgcacccggt cgcgcagcgg ccgcgaccac cgcggcggga tcgccgccgc
    21841 cccgcacagc accccggcga ccgatccggc cgtcgcgccg ttggagtccg tgtccaggcc
    21901 gccgcgcacg gtcagcgtga tcgtgcgggt gaagtcgccc tcgccgtgga gcagtccggc
    21961 ggtcagcacc gccgcgttgg gcaccacgtg gatccagccg aggccggccg tgcgcgccgc
    22021 catctcgtcg agcgtctccg accagccgag ccccgcctcg tacagcgcga ccgtctcccg
    22081 tacggtccgg gcgaggcggc tgcccgccgg caccacctcc agggacgtga ccagggccga
    22141 gcgggcgtcg ggcgcggtga aggcggcggc gaccagggcg gccgcccaca tcgccccgta
    22201 caccccgttc ccggtgtgcg agaccaccgc gtcccggcgg gccaggccgg ccgcccggcg
    22261 cgggtcgccg gggctcgtcc agccgtagac gtccgccctg atcagcgccc cgatccactc
    22321 ctggtagggg ttgtcgcggg tggcggtgag cggcggtcgc agcccgttgg cgaggttccg
    22381 gtacgcggcc cgctcggcgg tgaacgtctg gaggtacggc agccgcagca gccacagctc
    22441 gccgacctgc tcggtggtga agccggagcc gtacgtctcc aggaggtgca gcccgagcag
    22501 cgtgtagtcg acgtcgtcgt cccggcagct ctcccggatc ccgccgcgca cgcaccgggg
    22561 ccactcgggc cgcaggacga agccgtccgc gccgg
//
