LOCUS       NZ_JABAOB010000012     21134 bp    DNA     linear   CON 23-OCT-2023
DEFINITION  Chitinophaga sp. Ak27 Ak27-scaffold_12_length_278140_cov_143.314,
            whole genome shotgun sequence.
ACCESSION   NZ_JABAOB010000012
VERSION     NZ_JABAOB010000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga sp. Ak27
  ORGANISM  Chitinophaga sp. Ak27
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 278140)
  AUTHORS   Yin,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2020) State Key Laboratory of Plant Genomics,
            Institute of Microbiology, Chinese Academy of Sciences, Beichen west
            road, Bejing 100101, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-AUG-2019
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 246.8x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/23/2023 02:22:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,312
            CDSs (total)                      :: 6,224
            Genes (coding)                    :: 6,211
            CDSs (with protein)               :: 6,211
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 13
            CDSs (without protein)            :: 13
            Pseudo Genes (ambiguous residues) :: 0 of 13
            Pseudo Genes (frameshifted)       :: 0 of 13
            Pseudo Genes (incomplete)         :: 11 of 13
            Pseudo Genes (internal stop)      :: 2 of 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:12:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 25902
            Orig. end                         :: 47036
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABAOB010000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21134
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21134
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21134
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11134](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11134)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    186..200
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.02"
                     /tool="antismash"
     gene            complement(546..1301)
                     /locus_tag="HGH90_RS29240"
                     /old_locus_tag="HGH90_29240"
     CDS             complement(546..1301)
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-166). E-value: 1.5e-17. Score:
                     56.0. Matches aSDomain:
                     nrpspksdomains_HGH90_RS29240_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012792498.1"
                     /locus_tag="HGH90_RS29240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29240"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_169192567.1"
                     /sec_met_domain="adh_short (E-value: 5.5e-36, bitscore:
                     117.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-40, bitscore:
                     133.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQLQNKTAVITGGNSGIGYATAADFLAKGAKVLITGRNPEAVQQ
                     AADTLGNDTDSFIADQGKIADTQKLAEYVRDRYGKIDILFVNAGIADFGPFSAVTEESF
                     DRLMDINLKGAFFTVQYLLPLIKDGGTIILLSSINALAGMPGGSIYNASKAGLNSLGRT
                     LSRELASRKIRVNVVNPGPVETPILQKAGIPEEAINKDEMAKKLPAGRIGQPEEIAKLV
                     SFLASDEASFITGAEYNIDGGFSVHPLIG"
     aSDomain        complement(804..1280)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HGH90_RS29240_PKS_KR.1"
                     /evalue="1.50E-17"
                     /label="HGH90_RS29240_PKS_KR.1"
                     /locus_tag="HGH90_RS29240"
                     /protein_end="166"
                     /protein_start="7"
                     /score="56.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVITGGNSGIGYATAADFLAKGAKVLITGRNPEAVQQAADTLGN
                     DTDSFIADQGKIADTQKLAEYVRDRYGKIDILFVNAGIADFGPFSAVTEESFDRLMDIN
                     LKGAFFTVQYLLPLIKDGGTIILLSSINALAGMPGGSIYNASKAGLNSLGRTLSR"
     CDS_motif       complement(846..905)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HGH90_RS29240_0002"
                     /evalue="1.10E-03"
                     /label="PKSI-KR_m4"
                     /locus_tag="HGH90_RS29240"
                     /protein_end="152"
                     /protein_start="132"
                     /score="11.5"
                     /tool="antismash"
                     /translation="ILLSSINALAGMPGGSIYNA"
     CDS_motif       complement(1188..1274)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HGH90_RS29240_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="HGH90_RS29240"
                     /protein_end="38"
                     /protein_start="9"
                     /score="17.6"
                     /tool="antismash"
                     /translation="VITGGNSGIGYATAADFLAKGAKVLITGR"
     misc_feature    1328..1341
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.05"
                     /tool="antismash"
     gene            complement(1438..1707)
                     /locus_tag="HGH90_RS29245"
                     /old_locus_tag="HGH90_29245"
     CDS             complement(1438..1707)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790568.1"
                     /locus_tag="HGH90_RS29245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29245"
                     /product="ArsR family transcriptional regulator"
                     /protein_id="WP_145673940.1"
                     /transl_table=11
                     /translation="MDLAVIEKAANAIADKHRLSIIMEVVKKGKLICGDVCEFTCLSQP
                     TVSHHVKILVDSGVLNSSKNGRIVELTLNKEMMKQLSMFFLQLS"
     gene            complement(1747..2637)
                     /locus_tag="HGH90_RS29250"
                     /old_locus_tag="HGH90_29250"
     CDS             complement(1747..2637)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.3"
                     /locus_tag="HGH90_RS29250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29250"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_168764560.1"
                     /transl_table=11
                     /translation="MGARNLHTPFELTQADMSAWDTAPKVYYFFEIMQIRQGSGYRIIN
                     QNRLPYDKGSIFLFTPQDCRGFEVSAATEFVSIRFSELFMGLSQVPQQKARLEEWLRQL
                     EYLFFAHNRQGQLQIRHTNDCKMIASLIENMVEEYEQKPPYYQDNLQHYVTLLLNIVAR
                     NVAEEVNVGENAAESSLINRLVAHIRQHIYQPELLKLEHLASVFHLSANYIGEFFKKQT
                     GESLQQYIINYKLNLVQLRVTHSDLTIGEIADELGFTDESHMSRLFKKYHGLTPAAYRR
                     EKMQGRKNMLEKNIH"
     misc_feature    2704..2721
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            2822..3295
                     /locus_tag="HGH90_RS29255"
                     /old_locus_tag="HGH90_29255"
     CDS             2822..3295
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS29255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_29255"
                     /product="hypothetical protein"
                     /protein_id="WP_169192568.1"
                     /transl_table=11
                     /translation="MKTIKKHLILPVVALSAFTACHDTKAPEEKVHTAFAPPQQAAVEN
                     EATITHPCAVLYSPDSIKLEKLKKDNGEEAFYTIADDNQNYMADARNFLEGKGVNILEP
                     ASGKLTFHSPKNHPTELDLNDKKYNWEIWLYDGNKLHKVDVTDIENEYAKYMK"
     gene            complement(3335..4234)
                     /gene="bla"
                     /locus_tag="HGH90_RS29260"
                     /old_locus_tag="HGH90_29260"
     CDS             complement(3335..4234)
                     /EC_number="3.5.2.6"
                     /codon_start=1
                     /gene="bla"
                     /gene_functions="resistance (resist) ClassA"
                     /gene_kind="resistance"
                     /inference="COORDINATES: protein motif:HMM:NF012099.1"
                     /locus_tag="HGH90_RS29260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29260"
                     /product="class A beta-lactamase, subclass A2"
                     /protein_id="WP_168764562.1"
                     /transl_table=11
                     /translation="MKKHYIFSVAATIACLNGFAQAGNRHTTLRQQIADIAGNISGKVG
                     VYAQLLETNDTVSFNRDQHFPMQSVYKFPVSMAVLQQVDAGKVGLDQPVRINKADLTTA
                     GVSPLRDKYPDGNVSLTVRELLDYNVRKSDGSACDILFKLLGGPEKVNAYVHGLGIRSI
                     NIATLEEAQVHKDNLQVQYRNWSTPAAMVQLLKKFFQDPVLSDSSKEHLLYLMTTSGPG
                     AKRLKGLLPEGTTVAHKTGTSWTVDGITAANNDVGIVTLPNGTHMAIAVFVSDSKANDE
                     ERDAAIAKIAKAVWDSWK"
     gene            4351..5385
                     /gene="proB"
                     /locus_tag="HGH90_RS29265"
                     /old_locus_tag="HGH90_29265"
     CDS             4351..5385
                     /EC_number="2.7.2.11"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012794379.1"
                     /locus_tag="HGH90_RS29265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29265"
                     /product="glutamate 5-kinase"
                     /protein_id="WP_145673948.1"
                     /transl_table=11
                     /translation="MSKPILVIKFGTASITHQNGDLDETVIAGIARQVAELHQDYHIVL
                     VSSGAVAAGKQFLRQYNGTISERKAAAAIGNPLLLNKYSRYFAPYNIAVAQSLCERTHF
                     SDRNQFLQLKRTYEELWASNIIPIANENDVVSSLELKFSDNDELATLIAVGFGASLLLF
                     STSVAGVLDREGKVVPQIDVIDKAALGLADKEKSALGLGGMVSKLTFARLATRMGIRVV
                     IFGIRTEDGILNAIAGKTGTLCLPQPCSMPARKKWLASGSLVTGRIQIDAGAQKALEKR
                     HSLLAVGVKAVLEKFECGEVIEIVNEDQVAIAVGRAKIASDVLDTHHKAQNTEVAHADD
                     IVLL"
     gene            5399..6646
                     /locus_tag="HGH90_RS29270"
                     /old_locus_tag="HGH90_29270"
     CDS             5399..6646
                     /EC_number="1.2.1.41"
                     /GO_function="GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012794378.1"
                     /locus_tag="HGH90_RS29270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29270"
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="WP_168764563.1"
                     /sec_met_domain="Aldedh (E-value: 1.7e-16, bitscore: 53.3,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTIQPLLEKAQQAGISIRTLPDAQKQSLLRRLAAVILIQSDAIT
                     AANKKDLDRMPDEDPKKDRLLLTEARIRDLASSLEAIAGLPDPANVLLLERTLDNGLLV
                     QKKTVPLGVVGVIYESRPNVTVDVAALCIRSGNVCVLRGGTDAFDTNTILVQLIQAVLK
                     EFGVDENAVQLLPTDRNLVTEMLTAVKYIDIIIPRGSEQLIEFVRANSRVPVIETGAGV
                     CHTYVEKTADLQQAATIVTNAKVSRPSVCNALDTVLVDEAVAADFLALLAPQLQSYGVD
                     IYADPTAFGILQQQQYPRLFAAAPEDFGREFLSLKCSVKVVPDTTAALSHIQHFSSRHS
                     EAIISRDTAVSERFLNEVDAAAVYVNASTRFTDGGVFGLGAEIGISTQKLHARGPFALE
                     KLVTEKWFVYGNGQVR"
     gene            complement(6685..7758)
                     /locus_tag="HGH90_RS29275"
                     /old_locus_tag="HGH90_29275"
     CDS             complement(6685..7758)
                     /EC_number="4.1.2.13"
                     /GO_function="GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008582265.1"
                     /locus_tag="HGH90_RS29275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29275"
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="WP_169192569.1"
                     /transl_table=11
                     /translation="MLSLEKISELLGKESDTLLQHQSKTISKDLLHLPGPDTVNKIYLP
                     SSRNPQVLRSLGQLFNHGRLSGTGYMSILPVDQGVEHSAGASFAKYPAYFDPENIVKLA
                     IEGGCNAVASTFGVLSAVSRQYAHRIPFIVKINHNELLTYPNRADQVMYGTVEEAWNLG
                     AVAVGGTIYFGSEQSDRQLVEVSQAFERAHELGMATILWCYLRNDAFKKDVDYHLSADL
                     TGQANHLGVTIQADIIKQKLPTVNGGYKALNTGNSSYGKLDERIYTELTSDNPIDLCRY
                     QVANCYMGRMGLINSGGASEGAADLAEAVRTAVINKRAGGMGLISGRKAFQRPMVEGAA
                     LLNAIQDVYLNEQITIA"
     gene            complement(7808..7975)
                     /locus_tag="HGH90_RS29280"
                     /old_locus_tag="HGH90_29280"
     CDS             complement(7808..7975)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS29280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_29280"
                     /product="hypothetical protein"
                     /protein_id="WP_168764565.1"
                     /transl_table=11
                     /translation="MAMNITPNKETTTTEPAPVREEPVIHDGSGGAFEGTELVTEERDD
                     KPTPKSPTPY"
     gene            8260..9993
                     /locus_tag="HGH90_RS29285"
                     /old_locus_tag="HGH90_29285"
     CDS             8260..9993
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.3"
                     /locus_tag="HGH90_RS29285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29285"
                     /product="hybrid sensor histidine kinase/response
                     regulator"
                     /protein_id="WP_169192570.1"
                     /transl_table=11
                     /translation="MKIIERLKTVFRKITKTGTEGVNDDELVARITLVNTLSLVLATLI
                     FIVGATFIVITPRLSIIIPSSIEFFATLFAIYLNHKRRYWAAAASTFLIQCVASVYFGI
                     LLSNIIELQAMIIFLISIIYLIFQDRPTRRVALIVAICILTMLETYYHYHLVSTIPLSI
                     HAAYIFRISAMFGVLTLIIVVSRPYIHSNDFNKQLKRSNHFKKIFVYQVTHELRTPLNA
                     IYGVAQLLKREIKLDENLKSIEVLVDQLLLASNHTRNIVNDVLDMAQIESGNTDTISNE
                     AFEITPFIEKLVDVSRVIAKSRNIKIKLSISEMPQVIIGDALKLNQVATNLLGNAIKYS
                     DKGSTINCYITGNQTSWSLHIVNMGNHIPEEKLKTIFDPFITDKRKYTEGAGLGLYIVQ
                     NKVNSMNGTITAESSPSGINSFKVVLPLIAGSLEDIQLDMLEEDNITDLSDIHVIVAED
                     NEMSAMLVSRFLKQIGCSVCLTANGSEVLEACQKRIPDIIIMDYHMDIMDGKDTLIRLK
                     RNPLLKKVPVIIATGDAFLESRDQMIAAGASAFVEKPLDYKSLVKILNQQLHPLSGELQ
                     E"
     gene            complement(10001..11134)
                     /locus_tag="HGH90_RS29290"
                     /old_locus_tag="HGH90_29290"
     CDS             complement(10001..11134)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.2"
                     /locus_tag="HGH90_RS29290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29290"
                     /product="hypothetical protein"
                     /protein_id="WP_168764567.1"
                     /sec_met_domain="T1TS (E-value: 3.4e-25, bitscore: 82.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHNVQMLAHARMQKMQKEYVAMMANGEVCFSLFQLFNHDEFRLD
                     EFCQSFRPHPYSRQLKRAAQEFCEKYDIWLENAEHYVTCAIYLFPTANLYRMINILKNC
                     TVDFYLNDTMGREVFTHLSPAEQEKCNVIREHMARLDSPFICQPDVADVEKANAEMMSD
                     ICNTSPVSWFEAFRKMYNYHIDVTHLDCNTNTMGRIPSVDEYIDMRGHISGMHHTIQLI
                     EYSDGQFLDWGWMENVNISSDMQRLQYVTAAIGCLMNDLFSFEKEVIDNSSDSNLLMIM
                     ALNDTTLTLKEVILKSAGIVQQLLLEFTVLVNRVRARSYQRLPADSEMVDKLDAHIGGL
                     ERCVQASWMWQVYTKRYKRVNSMWKETQLAPITAAAV"
     misc_feature    11313..11329
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.35"
                     /tool="antismash"
     gene            11381..11956
                     /locus_tag="HGH90_RS29295"
                     /old_locus_tag="HGH90_29295"
     CDS             11381..11956
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790561.1"
                     /locus_tag="HGH90_RS29295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29295"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_168764568.1"
                     /transl_table=11
                     /translation="MTQIAIIRHGTTSWNKAGRLQGHSDIPLDEEGIMQALKLGQWLTR
                     ESWDLVYSSHLIRARQTAAIIAQELQINAVIEDSRIGEAGGGLIEGTTEAERLAKWGEN
                     WKQMDLGMETNASVLQRGNAFIQDLLAENSGKRILLITHGSFIRQMLDALLPEMHPTPP
                     MKNTSLTKLQFTDPNWRCDLFNCVRHLE"
     gene            11974..12693
                     /locus_tag="HGH90_RS29300"
                     /old_locus_tag="HGH90_29300"
     CDS             11974..12693
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012788921.1"
                     /locus_tag="HGH90_RS29300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29300"
                     /product="response regulator transcription factor"
                     /protein_id="WP_168764569.1"
                     /transl_table=11
                     /translation="MKLLLIEDEPAVVSVITRGLAEAGYEVSVAPDGNSGLQMALNNPS
                     FRLIILDVMLPGLNGIEVCRSLRKAQLEVPILMLTALGTTENIVMGLDSGADDYLVKPF
                     KLQELEARIRSLLRRKANNTDIPVVPTSPAILSLADLELDTDTKTANRQGKTIALTATE
                     YRLLEYLLKNPRKVLSRLEILEQVWGIEFNMNTKVVDVYINYLRKKINKHNPAELIHTV
                     VGLGYMIRENKADENTY"
     gene            12677..14035
                     /locus_tag="HGH90_RS29305"
                     /old_locus_tag="HGH90_29305"
     CDS             12677..14035
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.3"
                     /locus_tag="HGH90_RS29305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29305"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_168764570.1"
                     /transl_table=11
                     /translation="MKIRTKILLLFAGLTVSTILMMSILVYYFANQHSFEDFYKRLEIR
                     AYLSAKATLPYYESDSAIYNEIRDEHLEKLPSEKEYFLPLAADSSIHNNEQLALPADFY
                     SQVIREKKATYREGDLFYEGVLYKSKQGLYIVIVSAINKYNAEYLGWLRRILIISSVAS
                     SLILIGAGIFFSRYILQPIRHMMGQVKSISSRNLHLRLNVENSGDEINDLANTFNNMLD
                     RLETAFETQNNFVSNASHELSTPLTAIIGEAELALNKERTSEKYIYSLQNILSEAGRLE
                     HITKSLLHLAQTGFDGKKQEWSQLRSDELLFTVKHTIDKLHPGNKVEIDYSLFPEEEDK
                     LLIPGNEQLLELALSNIVMNAVKYSNNQPVSIALAATEKKNIIIVKDLGIGIPAEDLPY
                     IFSPFFRASNTSHFKGYGIGLPLAMNIIRMHKGDIIVNSQINHGTEIRVELPL"
     gene            14145..14630
                     /locus_tag="HGH90_RS29310"
                     /old_locus_tag="HGH90_29310"
     CDS             14145..14630
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS29310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_29310"
                     /product="hypothetical protein"
                     /protein_id="WP_168764571.1"
                     /transl_table=11
                     /translation="MKNILIPTDFSIRSLSYVHSIVAQHPYEQVNIILMHALQMPDSLF
                     DLVTYTRNSRHVELISADFQDGCEIIRNKYSSAIHQLKIEFFHGSTRAALRNFLLAQNI
                     DLIIQPVDHEYTPPSKRSYDPEKLISKCNYPKMKIQLQKQRFVANMSTISALLLATE"
     gene            14641..15555
                     /locus_tag="HGH90_RS29315"
                     /old_locus_tag="HGH90_29315"
     CDS             14641..15555
                     /GO_function="GO:0005254 - chloride channel activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014222523.1"
                     /locus_tag="HGH90_RS29315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29315"
                     /product="bestrophin family ion channel"
                     /protein_id="WP_168764572.1"
                     /transl_table=11
                     /translation="MLLKKNIPLKYVFGKIRFEIMLVAVYSLTINILYYRYDVTNLVIP
                     IAVPMVLGTVLSLLLAFRSNQAYDRWWEARSIWGAIVNDSRSLTRQVLSLMDATYQSED
                     LTLFQERFVKRQAAWCYSLGQSLRKTDPLKGLDRLLTRRELNYLMKYDNVPAALLLLHG
                     KDLKYALEQGWINQYQQIALDETLSRLCDAMGKCERIKNTVFPATYSLYTHFTLIFFIL
                     LLPFALIDVLGFMEIPLVVAIASSFLLIEKMAINLQDPFENKPTDTPVTTISRNIEKDL
                     RQMLHEQYHAPEEPEEKPAYYVL"
     gene            complement(15645..16385)
                     /locus_tag="HGH90_RS29320"
                     /old_locus_tag="HGH90_29320"
     CDS             complement(15645..16385)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS29320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_29320"
                     /product="hypothetical protein"
                     /protein_id="WP_168764573.1"
                     /transl_table=11
                     /translation="MFPFWSDYYYLVIILQIICAVHALKNGRREWLFFIIFVPLIGVAV
                     YFIREILPELSSGDVGEKLMRSIWPDGRIKEWERKVRISDTVTNKLQLADAYAQRQQYE
                     KAISLTQECAHTFTKDPGILLQLARYQFLGGYYAGSIQNFDRVNASKGVRMSKVEDELM
                     YAQALEYTGQPDLAEAAYQKIIQVHHSLEAMYYYGLMLKKQQRIAEARAQFEHTKAEID
                     LHPKYVRRTLRKWVALSKKELSGL"
     misc_feature    complement(16338..16354)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.98"
                     /tool="antismash"
     misc_feature    16338..16354
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 26.54"
                     /tool="antismash"
     gene            16475..17152
                     /locus_tag="HGH90_RS29325"
                     /old_locus_tag="HGH90_29325"
     CDS             16475..17152
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012794348.1"
                     /locus_tag="HGH90_RS29325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29325"
                     /product="TIGR02117 family protein"
                     /protein_id="WP_317166187.1"
                     /transl_table=11
                     /translation="MKKVLKCIAYTLLTFFSLIGIYLLSAYTLSRMSTTKELVNDADIP
                     IYILTNGVHTDLVVPVRTVQIDWSTRIPYHNTIANDSSAQLLAFGWGDKGFYLETPTWA
                     DLKVSTAFKAAFNLSTAAIHATYYHRLQENESCCRIMISASQYARLILYINDSFKTGAD
                     GLPVKINTTANYDNNDAFYEAKGSYNLFHTCNTWANSGLKSCGQKACRWTIFDTGIFYQ
                     YRQ"
     gene            complement(17217..17618)
                     /locus_tag="HGH90_RS29330"
                     /old_locus_tag="HGH90_29330"
     CDS             complement(17217..17618)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_29330"
                     /product="hypothetical protein"
                     /protein_id="WP_169192571.1"
                     /transl_table=11
                     /translation="MKKMMNYVLVAGMGLVAVGMIPATVSGNTMGHRHHMKKEERREER
                     RMRKEEKNHIEIISPAQSGNMMPQAALPVTEAYVPKEVVNTFESKYGSALYDITPLQGA
                     NGVDRYCVRTLNNGVAEAVTVDGSGAPAM"
     gene            18025..18723
                     /locus_tag="HGH90_RS29335"
                     /old_locus_tag="HGH90_29335"
     CDS             18025..18723
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013989.3"
                     /locus_tag="HGH90_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29335"
                     /product="RibD family protein"
                     /protein_id="WP_168764575.1"
                     /transl_table=11
                     /translation="MNKPYIICHMVASINGKILTENWEHPQKVKQYSALYNKIHEDYHT
                     QGWILGRVSLEKDFYEGAKAELIQPTNTMSRAPFIGDKTAKSFAVTVDTKGKLAWDTNE
                     IGGDHIIAVLTEDVSDDYLYYLQRKKISYVFAGKKEVDIKKALHHLTTLFPIKQLMLEG
                     GSILNGTFLNEGLIDEFSVLIVPIADGTPNTPTVFEITNQAGKGKAALLKLAGVEKLAG
                     DVVWLRYVSK"
     gene            18737..19318
                     /locus_tag="HGH90_RS29340"
                     /old_locus_tag="HGH90_29340"
     CDS             18737..19318
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014216947.1"
                     /locus_tag="HGH90_RS29340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29340"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_169192572.1"
                     /transl_table=11
                     /translation="MTDTSFFQTIYHHPLLKDNDYKAIAEAHTKIDLTPGMLLLEAGKT
                     AREFYAIEQGLCRSFLYDYNGNEITTEYYCPGDILIESFSLFQRIPSNENFQAIPAVTA
                     WKIAYDDFQQLLQTVEGFREWGRNWATHQLFVLKQRSIQAFTVSATDRYLQLIATRPTI
                     VALSPLKYIASYLGITDSSLSRIRKEIAAG"
     gene            19399..19782
                     /locus_tag="HGH90_RS29345"
                     /old_locus_tag="HGH90_29345"
     CDS             19399..19782
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014216948.1"
                     /locus_tag="HGH90_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29345"
                     /product="VOC family protein"
                     /protein_id="WP_169192573.1"
                     /transl_table=11
                     /translation="MKNAVNWFEIYTSDFKRAKKFYTDVFKCTLTDLPVNNDRHSQMEY
                     AVFAGNEQAPNACGALVKLDVAPPGIGGTLVYFDTVDIEDTLSRVEGAGGKVVRPKQNI
                     GEYGFIALIEDSEGNMIGLRSGK"
     gene            complement(19859..20788)
                     /locus_tag="HGH90_RS29350"
                     /old_locus_tag="HGH90_29350"
     CDS             complement(19859..20788)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF027713.3"
                     /locus_tag="HGH90_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_29350"
                     /product="DUF5007 domain-containing protein"
                     /protein_id="WP_168764578.1"
                     /transl_table=11
                     /translation="MKAFMNIKNKWWLLIAVFAASCKKDSTDGFLSPALKYTNPSIKVA
                     VGASLIQSGAMVTDESTKPLTFSIDGIYYEDGKLADKVMAYKVDTYFWQAEYTGKEKTV
                     EELNQKRTKVNRPAIDINPENGNIVIYPEASDTTQLVKGKYIIDVRVKNSGGEIVVKKA
                     LTIDVSYALPYYYRFAGVDGNLTGIDVTFDRQQPTGNKILVYVLKKDGSPVDPKLLLGY
                     DYSSTPGVTDLKDWHSLGLNNPTKYTEFPDHLELEIAGYPLPFVAGQVLRIDMYNNGEV
                     NGQYFNYWFDMAILKEGIWKVTIKLKYN"
ORIGIN
        1 acggatctta cgatccgcca gctccctcga caatgttctt cccaatgaat tcagcgctgc
       61 cttgctggcc gataccacgg tagcattagg tgtgcctgaa tatgcattca gggccgacaa
      121 cagggtgata gaaccaccat cgttgatcag tggcagtaac cgttggatgg tgaagaaagc
      181 gcctttgaaa ttcacattca tcaattcatc gtataactcc ggcgttacgt tgccaaaggg
      241 cgccagcttc gccactcctg cattgataaa caggctgtct atttttccgt agcggcgttg
      301 cacatattct gccagtctct ttgcatcttc cggtacggcc tggtcggcct taaatccttc
      361 ggcagggtgc ccgagtgcgt atactgcctg ttgtaccgca cccggattac gtcctgttat
      421 caataccctt gctccttttc ttaaaaatgt ggccgctgtt gtatatccta taccgctgtt
      481 accgcccgtg ataacaacta ctttatcttt cagagatgat gacatgaaat gttgtttttt
      541 tgagattaac caatgagggg atgaacactg aagccgccat caatattgta ttctgcgccg
      601 gtgatgaaag aggcttcatc tgaggcgagg aaggatacca gtttggcaat ttcttccggc
      661 tggcctattc tgccggcagg taatttcttc gccatctcgt ctttattgat cgcctcttca
      721 gggatgccag ccttttgcag gataggcgtt tccaccggac caggattgac tacgttgacc
      781 ctgattttgc ggctggccag ctcacgggat aatgtacgac ccagtgagtt aagccccgct
      841 ttgctggcat tatagatcga tccgccaggc atgccggcaa gggcgttgat ggaggataat
      901 aagatgatgg tgcctccgtc ttttatcagc gggagtaagt actgtaccgt aaagaaggcc
      961 cctttcagat tgatgtccat gagccggtcg aatgattctt ctgttactgc tgaaaaaggc
     1021 ccaaaatcgg cgatacctgc gtttacaaac aggatgtcaa ttttgccata acggtcacgt
     1081 acatactccg ctaatttttg tgtatctgct atcttgccct ggtctgctat aaaactgtct
     1141 gtgtcattac ccaacgtgtc cgcagcctgc tgtacggctt ccgggttacg tcctgtgatt
     1201 aatacttttg cgcctttcgc caaaaaatcc gctgctgtgg catatcctat tccgctgttg
     1261 cctcctgtaa ttactgctgt tttattttgc aactgtccca tcctattgat tcatttaaga
     1321 ttatcgatat aattactttt aaaaaaagag aaattacttt ctcattaatt cataaattta
     1381 aaaacttcaa tgtatttatt cataaaaaaa gccggtggta acctgcccgt tggcccctca
     1441 gcttaattgt aaaaagaaca tggacaattg cttcatcatc tctttattga gtgttaactc
     1501 cacaattctg ccatttttgg aggaattcag caccccacta tccaccagga tctttacatg
     1561 gtgcgatacc gtcggttgcg acaaacatgt aaactcacat acatcaccac aaatcagctt
     1621 gcccttctta acaacctcca tgattataga taaccggtgc ttgtctgcga tggcatttgc
     1681 tgctttttct ataactgcta aatccataga acaaaagtaa tactattttc taaatatcga
     1741 aatatttcaa tgaatatttt tttccagcat atttttccgg ccctgcattt tctccctccg
     1801 gtatgctgcc ggcgtaagcc cgtggtactt cttgaacaag cggctcatat gactttcatc
     1861 cgtaaaccct agctcatccg ctatctcccc aatagttaaa tcgctatggg taacccttag
     1921 ctgtaccagg ttcagtttat agtttataat gtattgctgc aggctctctc ccgtttgctt
     1981 cttgaaaaac tcccctatat aattagctga caggtgaaat accgacgcca ggtgctccag
     2041 ttttagcaat tccggctggt aaatatgctg ccggatatgc gctaccaggc ggttaatcag
     2101 cgacgactcc gctgcatttt cgccaacatt cacctcttct gctacatttc ttgccacaat
     2161 attgagtaac agggttacat aatgctgcaa attatcctgg tagtaaggcg gcttttgctc
     2221 atattcttcc accatatttt caatcagcga cgcaatcatc ttacaatcgt tcgtatgccg
     2281 gatttgcaac tgtccctgcc ggttatgcgc aaaaaagaga tactccagct gccgtaacca
     2341 ttcctccagc cgcgctttct gttgtggtac ctggcttagt cccataaaca actcagaaaa
     2401 acggatagac acgaactccg tggcagctga tacttcaaag ccccggcagt cctgcggcgt
     2461 aaacaggaat atactccctt tatcatatgg caacctgttc tggttaataa tacgataacc
     2521 gctcccctgg cgaatctgca tgatctcaaa gaaataatac accttcggtg ctgtatccca
     2581 tgccgacata tcggcctggg ttaactcaaa tggtgtatgt agattacgtg cacccataac
     2641 ctgctaaatt acaataatca ctccggatac cagcatgata atgattgacg ggccagacaa
     2701 gattatcctt ttatgatgaa atcttattta ttgccgcccg tatattttta tattatcttt
     2761 aggcaccagc ggctgttgat ctactcaaca gccgtgttat taaatatgcc aaactattac
     2821 tatgaaaacc atcaagaagc atctcatcct tccggttgta gcactatccg cgtttactgc
     2881 ctgtcacgac accaaagcgc cggaagaaaa agtccataca gcatttgcac cgccgcaaca
     2941 ggcagctgta gaaaatgaag ctaccatcac acatccttgc gcggtgttat attcacctga
     3001 tagcattaaa ctggaaaaat taaaaaaaga taacggagaa gaggcctttt acacgattgc
     3061 cgacgataac cagaactata tggcagatgc gcgtaacttc ctggaaggca aaggtgtaaa
     3121 tatactggaa cctgccagcg gaaagctgac ctttcactca ccgaaaaatc atcctactga
     3181 actagatctg aatgataaaa aatataactg ggaaatatgg ttgtacgatg gtaacaaatt
     3241 acataaagta gacgttaccg atatagaaaa tgagtacgca aaatatatga aataacaccc
     3301 tgcaggagaa tgatcctttc ggatcgttct ccttttattt ccaactatcc cacaccgctt
     3361 tcgcaatctt cgcaattgca gcatcccgct cctcatcatt cgccttcgaa tcggatacaa
     3421 atacagcaat cgccatatga gtgccgttag gcaaagtaac aatgcctacg tcattgttgg
     3481 ccgctgttat gccatctacc gtccatgaag tgcctgtttt gtgcgctact gttgttcctt
     3541 ccggcagcaa tcctttcagc cgttttgctc ccggtccgga ggtggtcatc aggtataata
     3601 aatgctcttt actggaatct gataataccg gatcctggaa aaacttcttt aacagctgta
     3661 ccatggccgc gggcgtggac cagttccggt actgtacctg taaattatct ttatgcacct
     3721 gtgcttcctc cagcgtggca atgttgattg accggatgcc cagtccatgt acataagcat
     3781 tcactttttc cggcccaccc agtaacttaa acagtatatc acaggcgctg ccatcgcttt
     3841 tacgcacgtt gtagtccagc agttcgcgta ccgtgaggct tacattgccg tcggggtatt
     3901 tgtcgcggag cgggcttaca cctgccgtgg tgagatctgc cttattgata cgtactggtt
     3961 gatccagccc tacttttccg gcatctacct gttgcaatac cgccatagat accgggaact
     4021 tgtatacgct ctgcatgggg aaatgctggt cgcggttaaa cgatactgtg tcatttgttt
     4081 ccagtaattg cgcatacacg cctacttttc cagatatatt tccggcgata tcggcaattt
     4141 gctgacggag tgtggtgtga cgattaccgg cttgggcgaa accgttcaaa caagctatgg
     4201 tggctgctac agaaaatata taatgcttct tcatatcgat gatgatgaaa atataaacgc
     4261 taatataact gataattctg cggcccggca aattttacat ttagaatttc gccgccttaa
     4321 tattatttta ggcgccaaat tgaggacaaa ttgagcaaac cgatacttgt tataaaattt
     4381 ggaacggctt ctattaccca tcaaaatggg gacctggacg aaaccgttat tgccggcatt
     4441 gcgcggcagg tggccgaatt acaccaggat taccacattg tgctggtatc atcaggggca
     4501 gtagctgccg gtaaacagtt tttacgccag tacaatggca ccatcagcga gcgtaaagcc
     4561 gctgccgcca tcgggaaccc gttgctgctg aacaaataca gccgctattt tgcaccgtat
     4621 aatatcgccg tagcccagag tctctgtgaa agaacgcatt tctctgaccg caaccagttc
     4681 ctgcaactga agcgcactta cgaagaattg tgggccagca acattattcc catcgccaac
     4741 gaaaatgatg tggtgagcag cctggagtta aaattttccg acaacgacga gctggctacg
     4801 ttgatagccg ttggttttgg cgcttcgctc ctgctcttca gcacctctgt ggctggtgta
     4861 ctcgaccgcg aggggaaggt tgtgccacag atagatgtta ttgacaaagc cgcgctggga
     4921 ctcgccgaca aggaaaagtc ggccttggga ctgggcggga tggtatccaa gctcaccttt
     4981 gcccgtttag ccacccggat gggcatccgg gtagtcatct ttggtattcg tacggaagat
     5041 gggatactca atgccatagc aggcaaaact ggtaccttgt gcctacctca accctgcagc
     5101 atgcctgccc gtaaaaagtg gctggccagc ggtagcctgg ttaccggccg tatacagata
     5161 gatgcggggg cgcaaaaggc actggaaaaa cgccacagcc tactggcagt gggcgtaaaa
     5221 gctgttctcg aaaaatttga atgcggggaa gtgatcgaaa ttgtgaatga agaccaggta
     5281 gccatcgccg tcggcagggc taaaatcgcg tccgacgtat tggatactca tcataaagca
     5341 cagaatacag aggtagcaca tgccgacgat attgtgttgt tataaccgga aataaatcat
     5401 gcaaacgata caaccattac tggaaaaggc acagcaggca ggcatatcca tacgtacctt
     5461 gcctgatgcg cagaagcagt cgctcctgcg gcgactggca gccgtaatcc tgattcaatc
     5521 ggacgccatt accgctgcaa ataagaaaga tctggaccgc atgccggatg aagatcctaa
     5581 aaaggaccgg ctcctgctta ccgaagcccg tatccgcgac ctggccagca gcctggaagc
     5641 gattgccggc ttgcccgatc ccgccaatgt gctcttactg gaacgtacgc tggacaatgg
     5701 tttacttgta cagaaaaaaa ccgtgcccct gggcgtggta ggcgttatct atgaatcacg
     5761 ccccaatgta accgtcgacg tagcggccct ctgtatccgt tccggcaatg tgtgcgtact
     5821 gcgtggcggc accgatgcct ttgataccaa caccatcctc gttcagctga tacaggcagt
     5881 attaaaagag tttggggtag atgaaaacgc cgtgcagttg ctgcctacag accgtaacct
     5941 ggtaacagaa atgctgaccg cggtaaaata tatcgatatc atcatccccc gtggttctga
     6001 acagctgatt gaatttgtgc gggccaactc ccgggtaccg gtcatagaaa ccggcgcagg
     6061 ggtttgccat acctacgtgg aaaaaacggc cgacttacaa caggcggcca ccatcgttac
     6121 caatgctaaa gtgtcccgcc cttcagtatg taatgcgctg gacaccgtac tggtagatga
     6181 agccgtagca gcagacttcc tggccctgct ggcgccacag ttgcaatcct atggcgtaga
     6241 catctatgca gatcctactg cctttggcat tttacagcaa caacaatatc cacggctatt
     6301 tgccgcggcg ccggaagatt ttggaaggga gtttttatcg ctcaaatgtt cagtgaaggt
     6361 agtgcccgac actaccgccg cgctgtcgca tatacaacat ttttcttccc gccattctga
     6421 ggcaattatc tccagggata ctgccgtgag tgagcgtttc ctcaatgagg tagatgcggc
     6481 ggcggtttac gtgaatgcgt caaccaggtt taccgacgga ggcgtatttg gcctgggtgc
     6541 cgaaataggt atatccaccc agaaactgca tgcccgtggg ccttttgcgt tggaaaagct
     6601 ggtaacagag aaatggtttg tatatggcaa tggccaggtg agataagata aaaatagccc
     6661 cgcatggcgc ggggctatgt atcattatgc aatcgtaatt tgttcgttca ggtatacatc
     6721 ctggatggca ttcagcaaag cggctccttc caccatcgga cgttggaatg ctttgcgtcc
     6781 ggagatcagt cccatgccac cggctctctt attaatgacc gccgtgcgta cggcttctgc
     6841 caggtcggcc gccccttccg atgctccgcc cgagttaatc aatcccatac gtcccatata
     6901 acagttagct acctggtaac ggcacagatc aatcgggtta tctgaggtta actccgtata
     6961 gatgcgttca tccagtttac cgtaagaaga gttgccggtg tttaatgcct tatatccgcc
     7021 atttaccgtc ggtagtttct gcttgataat atccgcctgg atggtaacgc cgaggtgatt
     7081 ggcctgaccg gtaagatcgg ccgacaggtg ataatccaca tctttcttaa aggcgtcatt
     7141 gcgcaggtag caccagagaa tggtagccat ccccagttca tgcgcccttt caaaagcctg
     7201 cgatacctcc accagctgcc ggtcggattg ctcagagcca aaataaatgg tgccgcctac
     7261 cgctaccgct cctaaattcc aggcttcttc cacagtgcca tacatcacct ggtcggcccg
     7321 gttgggatag gtgagcagtt cattgtgatt aatttttaca atgaagggaa tccggtgtgc
     7381 atattgccgc gatacggccg atagcacacc aaaggtggaa gctaccgcat tgcaaccgcc
     7441 ttctattgcg agcttcacga tattttccgg atcaaaataa gcaggatatt tcgcgaaaga
     7501 agcgccggca ctgtgttcta ccccctggtc aaccgggagt atcgacatat agccggtgcc
     7561 ggagagtcgc ccgtgattaa atagttgtcc caggctgcgc agcacctgtg ggttccggct
     7621 ggagggcagg taaatcttat ttaccgtatc gggaccaggc aggtgcaaca aatctttgct
     7681 gatggtcttg ctttggtgtt gcaggagggt atcgctttct ttccctaata attcgctgat
     7741 tttttccaag gataacataa gctttacttt tttggtacaa ctaatttaaa catttaaagg
     7801 tatccactta gtacggagta ggactctttg gtgtaggttt gtcatcccgt tcttccgtta
     7861 ccagctctgt gccttcgaac gcgccgccgg agccgtcgtg aataacaggt tcttctctaa
     7921 ccggtgcagg ttccgttgtt gttgtttctt tgttaggagt aatattcatg gccataatga
     7981 caaatgtaag cattaccggg aaaatgcagg tccggggtag gttttgaaaa aaataatgat
     8041 aatttgatgt taggaggaaa tactataact ttataagtaa gtatccaacc cccttaaaag
     8101 gataccggga agaactagca ctggaaatca accctcagaa gatcattaat gcgttatgaa
     8161 ctaagacatt tacctacaac tagacttaaa catttgctta ctgattaagt cggtttcgaa
     8221 tttaatgttg ctaaatccta cgactactta attatgacca tgaaaattat agaaagacta
     8281 aagaccgtct tcagaaaaat aaccaaaaca ggcacagaag gagtgaatga tgacgagctg
     8341 gtagcaagaa taacgcttgt gaatacactt agtctcgtgt tagctacgct tatcttcatc
     8401 gtaggagcta cattcatcgt tataacaccg cggttgtcta tcatcattcc aagcagcatc
     8461 gaatttttcg caacgttgtt tgccatctat ctaaatcaca aaagacgcta ttgggcagct
     8521 gcagcgagta cgttcctcat tcaatgcgtt gcatcagttt atttcggcat actgttaagc
     8581 aatatcattg aactacaggc aatgattata ttcctgatat ccatcattta cctgatattc
     8641 caggaccgtc caacgagaag agtagcgctg attgtggcga tatgcatatt gacaatgctg
     8701 gaaacctatt atcattatca tttggtatct actatcccat tgagtataca tgccgcttat
     8761 attttccgta tatcagccat gtttggtgtt ttaaccctga ttattgttgt cagcaggcct
     8821 tacattcaca gtaatgactt caacaaacaa ttaaaaagaa gtaatcactt taagaaaata
     8881 tttgtttacc aggtaacaca tgaactcaga accccattaa acgccatcta tggtgtagct
     8941 caattattaa agcgggaaat aaaattagat gagaacctga agagcataga agtgctggta
     9001 gatcaattat tactggcgag caaccatacc aggaacatag tcaatgatgt gctggacatg
     9061 gctcaaatag aatctggaaa tactgatact atctccaatg aagcatttga gataactcca
     9121 ttcatcgaaa aactggtaga tgtaagcagg gtaattgcca aatcgagaaa tattaaaatt
     9181 aagcttagta tcagcgaaat gccacaggtg attattgggg atgcgttaaa actaaaccag
     9241 gtagccacca acttattagg aaacgccatt aaatactcag ataagggctc caccataaat
     9301 tgctatatta ctggcaacca aacaagctgg tcgctgcata tcgttaatat ggggaaccat
     9361 attccggaag aaaagcttaa aaccatattc gatccgttca tcacagacaa gcggaagtac
     9421 actgaaggtg caggtttggg gctttatatt gtgcaaaata aggtcaattc catgaacggc
     9481 actattacgg ccgaaagcag tccatcaggc atcaacagct tcaaagtggt gctaccgctg
     9541 attgctggca gcctcgaaga tattcaactg gatatgctgg aagaggacaa cattacagac
     9601 ctgagtgaca tccacgtgat tgtggcagaa gataatgaaa tgagcgcgat gcttgtctcc
     9661 aggtttctaa aacaaatagg ttgttctgtt tgcctgacgg caaatggctc tgaagtactt
     9721 gaagcctgtc agaaacgtat tcctgatatt attatcatgg actaccacat ggatatcatg
     9781 gacggtaaag acacattaat acggttaaaa agaaatccgc tacttaagaa agtacccgtt
     9841 ataatcgcca ctggcgatgc tttcctggaa tcccgcgatc agatgatagc cgcaggtgca
     9901 agcgcttttg ttgaaaagcc gcttgattac aagtccctgg taaagattct caaccaacaa
     9961 ttacatccac tcagtggcga attacaggaa taattcttaa ttagacagca gccgcagtaa
    10021 tgggagccaa ttgcgtttct ttccacatgg aattgactct cttataccgt tttgtataaa
    10081 cttgccacat ccagcttgcc tgaacgcatc tttcaagccc tccgatatga gcatccagct
    10141 tatcaaccat ttcagagtct gcaggcaacc gttgataact ccgcgcccgc accctgttaa
    10201 ccagtactgt aaattccaat aatagttgct gtacaattcc ggccgatttt aaaatgacct
    10261 cttttagagt gagtgtagtg tcatttagcg ccatgatcat caacaaattt gaatcagagc
    10321 tgttgtcaat cacttctttt tcgaaagaga agagatcatt catcaagcag ccaatggcgg
    10381 cggtaacgta ttgcaaacgc tgcatatctg acgaaatatt cacattttcc atccaccccc
    10441 aatccaggaa ttgcccatcg ctgtactcaa tcaactgaat cgtatgatgc attccggaaa
    10501 tatgccccct catatcaata tactcatcaa cgctggggat gcgccccatt gtattggtgt
    10561 tacagtctaa atgcgtaaca tcaatatgat aattgtacat cttgcggaat gcctcaaacc
    10621 aacttaccgg cgatgtatta cagatatctg acatcatttc tgcattagct ttttcgacat
    10681 cagcaacatc cggctggcaa ataaatgggc tatctaacct tgccatatgc tcccttatca
    10741 cattacactt ctcttgttct gccgggctga gatgtgtaaa aacttctctt cccatggtat
    10801 cattcaggta gaaatcaacc gtacaattct tgagaatgtt gatcatacga tacaagttag
    10861 ccgttggaaa aagatatatg gcgcaggtta cataatgctc tgcgttttcc agccagatat
    10921 cgtatttttc gcaaaactcc tgggctgccc gttttaattg acgtgaataa gggtgcggtc
    10981 tgaatgattg gcaaaattca tccaaccgga attcatcatg attaaatagt tgaaataacg
    11041 aaaaacatac ttctccattt gccatcattg caacatattc cttttgcatt ttttgcattc
    11101 tggcatgggc cagcatctga acattgtgtt tcataattgt ttgttttgag taaaaagaaa
    11161 agatgaaaaa ccaatttcta agtaaggtcc tgatttaaga gaggggtgtg tcttgcaggt
    11221 tcagctaagg gatgaaaagg tataccggga aatagtttga acaaatatat tatactttta
    11281 atatacaaaa aatcactgga ttataattac tactgtaatt ttactattaa ccccgccatg
    11341 atttacctat atttgtcccc cggaattcaa aactgcccat atgacccaaa ttgcgattat
    11401 tcgccatgga actacttcct ggaacaaagc cggtagatta caaggacatt cagatatccc
    11461 cctggatgaa gaaggtatta tgcaggctct caaacttggg cagtggctca cccgtgaatc
    11521 atgggatctg gtgtattcga gtcatttgat cagggccagg caaaccgctg cgatcatagc
    11581 ccaggaatta caaatcaacg ctgttattga agacagcaga atcggggaag ccgggggagg
    11641 cctcatcgaa ggcaccaccg aagccgaacg gctggccaaa tggggcgaaa actggaaaca
    11701 aatggacctc ggcatggaaa ccaatgcctc cgtactccag cggggcaatg ccttcatcca
    11761 ggacctgctc gccgaaaact cgggcaaaag gatactcctc attacccacg gcagctttat
    11821 ccgccagatg ctggatgccc tcctgccgga aatgcatcct accccgccca tgaaaaatac
    11881 ttccctcacc aagctgcagt ttaccgatcc caactggcgc tgcgacctct ttaattgcgt
    11941 gcgccatctc gaatagcctt atctttaccc gtcatgaagc tattactgat agaagatgaa
    12001 cctgctgtag tatccgttat tacccgcggc ctcgctgaag ccggctacga agtcagcgta
    12061 gctcccgacg gcaacagcgg cctccaaatg gcgctcaata acccatcctt ccggctcatt
    12121 atactcgatg taatgctgcc tggcctcaat ggcatcgagg tatgccgctc cctgcgaaaa
    12181 gcgcagctgg aagtgcctat actcatgctt accgccctcg gcaccaccga aaatattgtg
    12241 atgggactcg atagcggcgc cgacgactac ctcgtaaaac cattcaaatt acaggagctc
    12301 gaagcccgca tccgcagcct gctcagaagg aaagccaata ataccgatat tcccgttgtt
    12361 ccaacgtcgc cggctatact tagtttggcc gacctcgagc tggatacaga taccaaaaca
    12421 gccaaccggc agggaaaaac cattgccctg accgctacag aataccggct gctggaatac
    12481 ctgctgaaaa atccccggaa agtgctctcc cgcctggaaa tactggaaca ggtatggggc
    12541 atcgaattta atatgaatac caaagtggta gacgtatata tcaactatct ccggaaaaaa
    12601 attaataagc ataacccggc agaactcatt cataccgtag tgggactcgg atacatgatc
    12661 agggaaaata aggccgatga aaatacgtac taagatatta ctgctgtttg ccggtttaac
    12721 cgtttccacc atcctcatga tgagtatact ggtgtattat ttcgctaacc aacactcctt
    12781 cgaggacttc tacaaacgac tggaaatacg cgcctatctc agtgccaaag ccacccttcc
    12841 ctattacgaa tccgattctg ccatctataa tgaaatccgg gatgaacacc tggaaaaact
    12901 cccttccgaa aaggaatact tcctccccct ggccgccgac agctccattc ataacaatga
    12961 acagctggcg ctccccgccg acttctactc ccaggtaatc agggaaaaaa aagccaccta
    13021 ccgggaaggc gacctcttct atgaaggcgt gctctataaa agcaaacagg gcctctacat
    13081 cgtgattgtt tctgctatca acaaatacaa tgcggaatac ctgggctggc ttcgcaggat
    13141 tttaatcatc agctccgtgg cctcgagcct gatattaata ggcgccggca ttttcttctc
    13201 ccgctatata ctccagccga tccggcatat gatggggcaa gtaaaaagta tcagctcccg
    13261 caatctccac ctgcggctca acgtagaaaa tagcggcgat gaaatcaatg acctggccaa
    13321 taccttcaat aatatgctcg accgcctgga aacggccttc gaaacccaaa ataactttgt
    13381 gagcaacgct tcccacgaac tgagcacccc gcttactgcc atcatcgggg aagccgaact
    13441 ggccctcaat aaagaacgta cctccgaaaa atatatctat tcgctccaaa acattctgag
    13501 cgaggcaggg cgactggagc atatcaccaa aagcctcctg cacctggccc agaccggctt
    13561 cgacggcaaa aagcaggaat ggagccagct ccgcagcgat gaattgctgt ttaccgtaaa
    13621 acataccatc gataaactcc atcccggcaa taaggtggag atcgactaca gccttttccc
    13681 cgaagaagaa gataaactgc tgattcccgg caatgaacaa ctgctggaac tagccctcag
    13741 caatatcgtc atgaatgccg tgaaatattc taataaccag ccagtatcca tcgcgctggc
    13801 agccaccgaa aagaaaaata tcatcatcgt aaaagacctg ggcatcggta tccctgcgga
    13861 agacctcccc tatatcttct ctcccttctt ccgggcctcc aatacgtccc attttaaagg
    13921 gtatggtatt ggtctgccac tggccatgaa tatcatccgt atgcataagg gcgacatcat
    13981 cgtaaatagc cagataaacc acggaaccga gatcagggtg gagcttccac tgtagacttt
    14041 gctttcttac cgaattctta ccacattctt acaacctttt aaccccgctc ttactggttc
    14101 cttatatgcg cccaataatt ttgtgatcat aaaagctacc agatatgaaa aatattctaa
    14161 ttccaacaga cttctccata cgatctctca gttatgtgca cagcattgtg gcacaacacc
    14221 cctacgaaca ggtaaatatc atattgatgc atgctttaca gatgcccgac tcgctgttcg
    14281 acctggttac ctacacccgc aacagcaggc acgtagagct gatttcggcc gacttccagg
    14341 atggttgtga aattatccgt aataaatatt cttccgctat tcaccagctg aaaattgaat
    14401 tctttcacgg cagcacccgc gcagcattgc gcaacttcct gctggcacaa aacatcgacc
    14461 tgatcatcca acctgtagat catgaatata cgccgccttc caaaaggagc tatgatccgg
    14521 aaaaactgat cagcaaatgc aactacccga aaatgaagat tcaattgcag aaacaacggt
    14581 ttgtggccaa catgtccacc atatcagcac ttttgctggc aacagaataa aagcaaggtt
    14641 atgttactca agaaaaatat cccccttaaa tatgtattcg gcaaaatcag gttcgaaatc
    14701 atgctggtag cggtttattc gctcaccatc aacatcctct attaccggta tgatgtcacc
    14761 aacctggtga tccccattgc agtacccatg gtattgggta cggtactttc cctcctgctg
    14821 gctttccggt ctaaccaggc ctacgaccgc tggtgggaag ccagaagcat atggggcgcc
    14881 attgtaaatg attcgcgctc actcacaagg caggtactca gtttgatgga tgcaacgtat
    14941 cagtcggaag acctgaccct gttccaggag cgctttgtaa agcgacaggc agcctggtgc
    15001 tatagcctcg gacaatcgtt acgcaagaca gatccgctga aaggtttaga cagactttta
    15061 acaagaaggg aacttaacta cctgatgaaa tatgataatg tgccggctgc cttgttgctc
    15121 ttacatggaa aggacctcaa atatgccctg gaacaaggct ggattaacca gtatcagcaa
    15181 atagcgctgg atgaaacctt gtcgcggcta tgcgatgcca tgggaaaatg tgaacgtatt
    15241 aaaaatacgg tgttcccggc tacctacagc ctgtacactc actttacgct catcttcttt
    15301 atactgttat tgccctttgc attgatagat gtgcttggat ttatggagat accactggta
    15361 gtagccattg cctcttcttt cctgctgata gaaaagatgg ccatcaacct gcaggatccg
    15421 tttgagaaca aacctaccga tacaccggtg accaccattt cccggaatat cgaaaaggac
    15481 ctccggcaaa tgctgcatga gcaataccat gcgccggaag aaccagaaga aaagccagcc
    15541 tactacgtgc tgtaaagata ctttgtgttt aaggtgttct tcccaaagaa ccgtatttat
    15601 agcgtagaaa taacgccccc tgcttcagcg gggggctctc ctttttacag gccgctcaat
    15661 tcttttttag aaagcgctac ccacttgcgt aaagttcgcc tcacatattt gggatgcagg
    15721 tctatttccg ctttggtatg ctcaaactgc gcgcgggctt cagcgattcg ctgctgtttc
    15781 ttcagcatca atccataata atacatcgcc tccagggagt gatgtacctg gataatcttc
    15841 tggtaggccg cttctgccaa atccggctgc ccggtgtatt ctagcgcctg ggcatacatc
    15901 agctcatctt ccactttgct cattcttact cccttgctgg catttacccg gtcgaagttc
    15961 tggatactac cggcataata tccacccagg aactggtagc gcgccagctg caataatatc
    16021 cccgggtctt ttgtaaaagt atgcgcgcat tcctgggtca gcgaaatggc tttttcgtat
    16081 tgctgccgct gcgcataggc gtcggccagc tgcaacttgt tggtaacggt atcagatata
    16141 cgcaccttac gctcccactc tttgatgcgt ccatcgggcc agatgctgcg catcagcttt
    16201 tcgcctacat cgccgctact cagctccggc aggatctcgc ggataaaata aacagctacg
    16261 ccaatcaggg gaacaaatat gataaaaaac aaccattctc ttctgccatt tttcagcgca
    16321 tgtacggcac agataatttg taatataata acaagataat aatagtcact ccaaaaaggg
    16381 aacatgtgta aagctgtaac cagggttaat aaaactgatt tgtctgcaaa ataaataaaa
    16441 ttactaattt gtcgatttca taaaacgtct tgaagtgaag aaagtactga agtgcatcgc
    16501 ctacaccctg ttaacctttt ttagcctgat cggtatatac ctgctatcag cgtataccct
    16561 ttcccgtatg agcaccacca aagaactggt aaatgacgca gacattccca tttatatcct
    16621 taccaatggt gtgcacactg acctggtggt gcctgttcgc accgtacaga tcgactggag
    16681 cacccgtatt ccctatcata acaccattgc caacgatagc agtgcacagc tcctggcctt
    16741 cggttggggc gataaaggat tttacctgga aacgcccacc tgggctgatc taaaggtcag
    16801 tactgccttc aaagccgctt tcaacttaag taccgccgcc atccatgcca cctactatca
    16861 ccgcctccag gaaaatgaaa gttgttgcag gatcatgatc agcgcctctc aatacgcccg
    16921 gttaatacta tatatcaacg acagctttaa aaccggcgcc gatggcctgc ctgtgaagat
    16981 aaacaccacc gccaattatg ataataacga tgctttttat gaagccaaag gcagttataa
    17041 cctttttcat acctgtaata cctgggctaa cagtggcctg aaaagctgcg ggcaaaaagc
    17101 ctgccgctgg acgatttttg atacggggat attttatcaa tacaggcaat aagctacaaa
    17161 aaagcctccc ggcatcacac caggaggcta aaatattcac ggataaaggg aaacaattac
    17221 atggccggag caccggaacc atccacagtg accgcttccg ctacaccatt gttcaacgtg
    17281 cgcacacaat aacggtctac cccattggcg ccctgaagtg gtgtaatatc gtataatgca
    17341 gatccatact tagattcaaa ggtgtttact acctccttcg gaacatatgc ttccgttaca
    17401 ggcaatgctg cctgtggcat catatttccg gattgcgctg gtgagataat ttctatatga
    17461 ttcttctctt ccttacgcat tctcctctct tcccttcttt cttctttctt catatggtga
    17521 cgatgcccca ttgtgttccc actaacagtt gccggtatca taccaacggc caccaaaccc
    17581 atacctgcta ccaatacata attcatcatc tttttcatag tctatggttt tagatgaaag
    17641 aatctgtttc caatgcaaag ttccgcaatt aggtattatg ccgcgcattt ttagcagggt
    17701 gaagagtaga tgcgggttgc gactcagcag ctgcgacagg ctcctgttag tcgctgcagc
    17761 cgatagcaga tagagcggct gtgggcaatt ttaacaatgt ataaatatag gataggaatt
    17821 atatgtgaga cttttctttc taaattattt tattttatca gaatgagata agctgataat
    17881 aaaatcttgt ttatataata tcattaaaat cctacttagt ctaaacggcc cattttttct
    17941 accttagccg ggaaaagtcc ggtatccttt gcatttttaa aaggatatct atcaacgggc
    18001 cgcattaccc ttaacttccc aacaatgaac aaaccatata tcatctgcca catggtggca
    18061 tccatcaacg gaaaaatact taccgaaaat tgggaacatc cacaaaaagt aaagcagtat
    18121 tctgctctct ataataaaat tcacgaagac tatcacacac agggatggat acttggccgg
    18181 gtatcgctgg aaaaagactt ttatgaaggc gctaaagcag aactcatcca acccaccaat
    18241 accatgagcc gcgctccttt cataggcgac aaaacagcca aaagctttgc ggtaaccgtc
    18301 gacaccaaag ggaagctagc ctgggatacc aacgaaattg gtggcgatca tatcattgct
    18361 gttcttaccg aagatgtcag cgatgattac ctctactacc tgcaacgtaa aaaaatatcc
    18421 tacgtctttg ccgggaaaaa agaagtagac atcaaaaaag ccttacatca tcttaccacc
    18481 ctgtttccca tcaaacaact gatgctcgaa ggcggcagca tcctcaacgg caccttcctc
    18541 aatgaagggc ttatcgatga attcagcgta ctcattgtac ccattgccga tggcacgccc
    18601 aataccccca ctgtatttga aattaccaac caggcaggta aaggaaaagc agccctactg
    18661 aaactggcag gtgtggagaa gttagccgga gatgtggtgt ggctgagata tgtatcgaaa
    18721 tagaaaatgt tgccagatga ccgacacctc tttcttccaa accatctatc atcatcccct
    18781 tctcaaggac aacgattata aagctatcgc cgaagcgcat acgaaaattg acctcacgcc
    18841 cggcatgctg ttgctggaag ctggcaaaac tgcccgggaa ttttatgcca ttgaacaggg
    18901 attatgccgg tcattcctgt atgattataa tggtaatgaa ataactactg aatattactg
    18961 tccaggtgat atactgatag aatctttctc cctttttcaa cgcatccctt ccaacgaaaa
    19021 cttccaggcc atcccggccg tcactgcgtg gaagatagct tatgatgatt tccagcagct
    19081 gctgcaaacg gtagaaggat tccgggaatg gggaagaaac tgggccaccc accagctatt
    19141 cgttttgaaa cagcgctcta tccaggcttt cacggtcagc gccaccgacc ggtatctgca
    19201 gctgattgct acaaggccaa ccatcgtcgc cctctctcct ttaaaataca ttgcctctta
    19261 cctcggcatc accgacagct cgctgagccg gatccggaaa gaaatcgccg caggctagca
    19321 tttcttgcca taggacaagt ccacttttgc cggcctcttt taattttgaa tcattgattc
    19381 aactttaaaa caggcaatat gaaaaatgca gtgaattggt ttgagatcta tacgtccgat
    19441 tttaagagag ctaaaaagtt ctatacagac gtatttaaat gtacacttac agatctcccg
    19501 gtcaacaacg acaggcatag ccagatggaa tacgccgttt ttgccggcaa cgaacaggct
    19561 cccaatgcct gcggcgcact ggtaaaactc gatgtagcgc cgcccggaat tggcggtacc
    19621 cttgtatatt tcgataccgt agatatagag gataccttaa gccgcgtgga aggcgccggc
    19681 ggtaaagtgg tccgtcccaa acaaaatatc ggcgaatacg gattcatcgc gttgatagaa
    19741 gattcggagg gaaatatgat cgggttacgg tcagggaaat gatgcggtag tagtaaataa
    19801 aaaaggggga acacgtagaa acgtgtatcc cctgattgct cactgtttac cgacaaccct
    19861 aattatattt caacttgata gtaactttcc agataccttc tttgagtatc gccatatcga
    19921 accaatagtt aaaatattgt ccgtttactt ccccattgtt atacatatca atcctcaata
    19981 cctgccccgc tacaaaaggc agcgggtacc cggctatttc cagttccagg tgatcgggaa
    20041 actccgtgta tttggtaggg ttgtttaaac cgagactatg ccagtctttc agatctgtta
    20101 cgccaggtgt agaggaataa tcatatccga ggagtaactt cggatccacc ggcgagccgt
    20161 ctttcttcaa tacgtatacc agtattttat taccggtagg ctgctgccgg tcgaaggtaa
    20221 catcgatgcc ggtgagattt ccatccaccc ctgcaaaccg gtagtagtat ggtaacgcat
    20281 agctcacatc aatggtcagc gcctttttta ccactatttc cccaccactg ttcttcaccc
    20341 tcacatcgat gatatatttt cctttgacca gctgcgtggt atctgatgct tcaggatata
    20401 taacgatgtt accattttcg ggattgatat caatcgccgg gcggtttacc tttgtgcgtt
    20461 tctgattgag ttcctctact gttttttcct ttccggtata ctccgcctgc cagaagtagg
    20521 tatctacctt ataggccatc accttgtccg ctaattttcc gtcttcatag tagatgccgt
    20581 ctatactgaa cgtcaacggt tttgtggatt catcggttac catagcgccg gattgaatga
    20641 gggaggcgcc cacggctact tttatggatg ggttggtgta cttgagcgcc gggctcagga
    20701 aaccatcggt gctgtctttt ttgcaggatg cagcaaatac cgcgatcagc agccaccatt
    20761 tgttttttat gttcatgaat gctttcataa taaagatcat taagattacc ggttatacct
    20821 ttgtttcagt cctgaagcga agctggcgcc attggtcaat acatgcacgg tggcattggc
    20881 tgttatcagg ttatgcgttt gaatagaccc ggtgaacctg gttgaatcta cacctggtat
    20941 tttcacgtgt acatactcca ggtaataagc ggaagtttgt atagagctgg tggcgcctgt
    21001 accgcctccc tttccgttga tataaacgct atcgccattg gcagcctggt aaaacttcga
    21061 cttatcattc accgcctgtt ccagcgaaat ccttccatct gtaatgatga agcgtttcag
    21121 caggttcaac aggg
//
