LOCUS       NZ_JABAOB010000001     10828 bp    DNA     linear   CON 23-OCT-2023
DEFINITION  Chitinophaga sp. Ak27 Ak27-scaffold_1_length_1986630_cov_140.309,
            whole genome shotgun sequence.
ACCESSION   NZ_JABAOB010000001
VERSION     NZ_JABAOB010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Chitinophaga sp. Ak27
  ORGANISM  Chitinophaga sp. Ak27
            Bacteria; Bacteroidota; Chitinophagia; Chitinophagales;
            Chitinophagaceae; Chitinophaga.
REFERENCE   1  (bases 1 to 1986630)
  AUTHORS   Yin,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2020) State Key Laboratory of Plant Genomics,
            Institute of Microbiology, Chinese Academy of Sciences, Beichen west
            road, Bejing 100101, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 19-AUG-2019
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 246.8x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/23/2023 02:22:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,312
            CDSs (total)                      :: 6,224
            Genes (coding)                    :: 6,211
            CDSs (with protein)               :: 6,211
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 4, 4 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 13
            CDSs (without protein)            :: 13
            Pseudo Genes (ambiguous residues) :: 0 of 13
            Pseudo Genes (frameshifted)       :: 0 of 13
            Pseudo Genes (incomplete)         :: 11 of 13
            Pseudo Genes (internal stop)      :: 2 of 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:12:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1643221
            Orig. end                         :: 1654049
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JABAOB010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10828
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10828
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5828](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5828)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(276..3257)
                     /locus_tag="HGH90_RS06405"
                     /old_locus_tag="HGH90_06405"
     CDS             complement(276..3257)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0071702 - organic substance transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04056.1"
                     /locus_tag="HGH90_RS06405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_06405"
                     /product="SusC/RagA family TonB-linked outer membrane
                     protein"
                     /protein_id="WP_169190683.1"
                     /transl_table=11
                     /translation="MKYIYLLFFLCLCTLEIQAQRTLYRNTGKDSSSTANADSIILSRV
                     TSTKRDTIGYLPNNELFLSRSINGAVSNVDVGEVKKLPYVSVDQMLVGRVTGVDIRTPS
                     AEPGKRNSVFIRGTSSLLLSNRDIFYAQPAYVVDGVPLIMDHAFAYDIQRFDFNRMGTE
                     TNLLSFLDVNDIERIEVLKDFGASAQYGPNAANGVISITTKAPRVGQMQVSVNAYAGLS
                     LRPSVDAVNGKYESDFRLPFYQKYANETQWRSFPRYLADSSQARYFGPANWDDLFLRNA
                     FTDGIQASVSGGTPLANFRFSIGQSSQQGVYDKTGIRRYDVNFGINIQPLKNLVFTTQV
                     AVANLNRKRNEFIRDRAGDEDYLFNYSSPLSPNKAYLQQYYTALDNTINRNKNNSARII
                     ANVKYSFASHFTWNTRFAIDYGQNFRDYFVPTSLGEGNSYVSNFDGLNKRLVLDNSLRY
                     ENTFSGKHHLEVTLGQYGQWDKWRYDYGRAYKGSSDYIKIYQPGSDDQKEGRFGNFRLM
                     FNTKDFTQSRLASFYSNIGYNFDGKYFVSLYVRRDGTSYLDAAHRWLVSPTVSASWKIS
                     QEDFLKDATWLSNLQLRGSWGRVGRLLMDEFYRGGPVYNVDAGWNGVPNMSTYNAFPVI
                     NAGYTTGYIVPGTSWPVVEQLNGGIDIGLFHDRVRASLDVYAKTDRNLVLKIPTLEEEG
                     YTGIVKNGMTIRNYGYELSVEADVIRREKFRWTTGISAYTNQNKLLALPDGLTDLVISQ
                     RRFLVGKPTDRYWLLINEGIYNSDGDVPVNPATGKKMTYQGVTLRKGDPRWRDLDGNYD
                     INDKDRVMKGRLSPAVTGGFTNTFYYRDWELNALVNYAFGRKIINQALANRFDFANREG
                     IDDPKAIKEISWWSKVQGDYSKVPAYNPWSAVYAYQPDQTLFLEDGSFVKLRAVTLAYN
                     LHSAWMKRSGIDHLRIYATGNNLLTWSPYKGGDPEAVSYFGYDEGYYNWAAPRTFTLGF
                     NFQF"
     misc_feature    complement(3752..3765)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    complement(3753..3766)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.79"
                     /tool="antismash"
     misc_feature    complement(3754..3767)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.15"
                     /tool="antismash"
     misc_feature    3755..3768
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    3756..3769
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.35"
                     /tool="antismash"
     gene            complement(3839..4264)
                     /locus_tag="HGH90_RS06410"
                     /old_locus_tag="HGH90_06410"
     CDS             complement(3839..4264)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019301.3"
                     /locus_tag="HGH90_RS06410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_06410"
                     /product="DoxX family protein"
                     /protein_id="WP_168762465.1"
                     /transl_table=11
                     /translation="MRTYARMARRLSVISDLPLLFMRLVLAYGFYLPARMKWSDIHGIG
                     DWFKQLHIPLPYISAYLVGCTEAAGVVLLTLGLFVRYITLPLMFSMVVAIATVHWSNGF
                     AAGDNGYEIPLYYLVMLFTLLVFGGGRIGVDYFLERS"
     gene            complement(4268..5017)
                     /locus_tag="HGH90_RS06415"
                     /old_locus_tag="HGH90_06415"
     CDS             complement(4268..5017)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021364.3"
                     /locus_tag="HGH90_RS06415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_06415"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_169190684.1"
                     /transl_table=11
                     /translation="MNLLPDTYHIQQTFSDWCRTGKKVQLPGVVADRLVHYRRLVFNNI
                     RDTMENAFPIAFNNIPSRKWDKMVKDFFAHHACQSYQLWKLPLEFYTYAVEHSWDEQYD
                     IPYLNDLLAFEWAEMELYNMEDIPAPAYLTEGNWLDTPLVLNQEHRLLSFSWPVHLKAK
                     RRELMTRKGVYFALLYRHPETGSIQFTDLSPWLAFLTEQLAQGITVRDILDYAPQLHIT
                     ETDTLESDTLAFLKEMQQQHFVLGFQS"
     gene            complement(5001..5828)
                     /locus_tag="HGH90_RS06420"
                     /old_locus_tag="HGH90_06420"
     CDS             complement(5001..5828)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008584484.1"
                     /locus_tag="HGH90_RS06420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_06420"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_168762463.1"
                     /sec_met_domain="DUF692 (E-value: 8.2e-98, bitscore: 323.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGVGFRREFAEELISGEHIRPDFVELAPENWMNIGGYWRKILHR
                     VVEKYPVLCHGLSLSIGSPDALNKEFLAYVKAFLQEYKVQLYSEHLSYSKCDNAHMYDL
                     LPIPFRMDAVRHIVSRIQQVQDYLQRPLAMEIVSYYTPVAAEMSEIDFINEVVKHSGCQ
                     LLLDVNNIYVNAFNHQYDAKAFIQQLPLSSVAYIHMAGHEQVAPDLIIDTHGEPIIDPV
                     YDLFEWTLAHLQPVPVLLERDFNIPEMIELQGELSRLKSICHKQWKLKDELVA"
     gene            complement(5905..6249)
                     /locus_tag="HGH90_RS06425"
                     /old_locus_tag="HGH90_06425"
     CDS             complement(5905..6249)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS06425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_06425"
                     /product="hypothetical protein"
                     /protein_id="WP_169190685.1"
                     /transl_table=11
                     /translation="MKNNKAINKNVLFSGSLVAGAIMGLASLQVSAKPVSYTNLGSGAA
                     VRNALTGTSGTAANAIELNCGAKKDSASAGKSKDGKCGQGKCGEGKCGNKKGEKKGKDK
                     TKPDTTKSGQ"
     misc_feature    complement(6275..6290)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.81"
                     /tool="antismash"
     gene            complement(6321..6599)
                     /locus_tag="HGH90_RS06430"
                     /old_locus_tag="HGH90_06430"
     CDS             complement(6321..6599)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS06430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_06430"
                     /product="hypothetical protein"
                     /protein_id="WP_169190686.1"
                     /transl_table=11
                     /translation="MGKHLHHLMPCCKDVTMLVEKRLQQEPLTWMQRLGLKFHLLLCVY
                     CRRYVKQTAIMHRQLQEYREAFTAPNEQVKQQWEALVAAYLKNDKDL"
     misc_feature    complement(6584..6595)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.66"
                     /tool="antismash"
     gene            complement(6602..7165)
                     /locus_tag="HGH90_RS06435"
                     /old_locus_tag="HGH90_06435"
     CDS             complement(6602..7165)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="HGH90_RS06435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_06435"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_168762460.1"
                     /transl_table=11
                     /translation="MTTCNPTVWVKLYADELFKFACSRVSDTGLAQDLVQDTFLSGLQA
                     MHQFRGESSEKTWLLAILKNKINDHFRMAGKAAITTLDMEARDQQLIFFNEKGHWRKEM
                     APRPWTTDINDKAEQADFFRILRTCMDKLTSLGKAVIQHKYLDEKKSADICKDLSLTSS
                     NYWVIIHRARLQLRACLEKNWFSN"
     misc_feature    7349..7369
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.79"
                     /tool="antismash"
     gene            7399..8115
                     /locus_tag="HGH90_RS06440"
                     /old_locus_tag="HGH90_06440"
     CDS             7399..8115
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS06440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_06440"
                     /product="hypothetical protein"
                     /protein_id="WP_168762459.1"
                     /transl_table=11
                     /translation="MKNEMSPVTYTYFVTLLKAYLRGTKTRQELIEELRGVTPWEEKEE
                     NIHTEVSRLLFQAANEVNENFYQDIVSAITHATDTAPTREGVIHQLEAVLTGFITPTHL
                     YQWATWHNEPDMEAVSFFNDIAVDYFCTQLLPASFEELTLTDYKQALKIFRSHHHDSLK
                     DKVALVLISQKERQRFLFYLSDYIQGHSSPEQLDVYLLHKFGMDHHSFPYMSAISAMMH
                     EPAKLPALLQMAAMSE"
     gene            complement(8117..9100)
                     /locus_tag="HGH90_RS06445"
                     /old_locus_tag="HGH90_06445"
     CDS             complement(8117..9100)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012790017.1"
                     /locus_tag="HGH90_RS06445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGH90_06445"
                     /product="acyl transferase"
                     /protein_id="WP_169190687.1"
                     /transl_table=11
                     /translation="MTVVSPDTIFSLQDNGLEAAALELFRYQYRENDLYRAYTDALHIA
                     PASVKSILEIPYLPIQFFKSHTVVSGIFEPELLFESSGTTQTINSRHLVKESAIYTRSF
                     MTAFEQFYGPVDDYVILGLLPSYLERQHSSLVRMVQEMVIRSGHPESGFYLYEHDKLYH
                     QLRALEARGQRVLLIGVTFGLLDFAEQYSLDLRHTIVMETGGMKGRREEWTRQEVHAFL
                     QERLGASVIHAEYGMTELLSQAYSKGNGLFASPPWMKILLRDENDPFQLSAGKGAGVIN
                     VIDLANIYSCAFIATEDIGRIHANGLFEVLGRLDNSALRGCSLMVS"
     misc_feature    complement(9067..9082)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.04"
                     /tool="antismash"
     gene            9250..9690
                     /locus_tag="HGH90_RS06450"
                     /old_locus_tag="HGH90_06450"
     CDS             9250..9690
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGH90_RS06450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGH90_06450"
                     /product="hypothetical protein"
                     /protein_id="WP_168762457.1"
                     /transl_table=11
                     /translation="MKKILFLFLVAGLLYACKKDKIGSKPILTFKGYTVDSVTSNLDKM
                     TVIMNVRDGDGDIEDTLWIATRYRNSGTSDTLYSVKQMGSIGANKGNSVNADVYINLLP
                     TEFKISHPFVADDSIHFVVFIKDNAGNFSDTVGTRGIPYNAQ"
     misc_feature    complement(9805..9825)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 28.19"
                     /tool="antismash"
ORIGIN
        1 cgcctgcagg tcgccgcgct tcgtcacctg gaaatcgccg gcacgtaatt caccgtacac
       61 ccaatgagcg ttttcattgg ccatggccgc ccgcatcaac gcatagcagg cagataaacc
      121 agcccgcgca tcatttttgg tctgccacat attctcttct gtcagcgccc ggtgcgaagg
      181 cacatccagc atctttttgc atgacagcat acctaccgcc aggaacagga tcattccggc
      241 aacagcaata tttttcatgg tcttggtttt aaacatcaga attgaaaatt gaagcccagg
      301 gtaaatgtgc ggggagccgc ccagttataa tagccttcat catagccgaa ataactcacc
      361 gcttccgggt ctccgccttt gtaagggctc caggtcagca ggttgttgcc tgtggcataa
      421 atgcgcaggt gatctatacc cgaccgcttc atccaggcag aatgcaggtt ataagccagg
      481 gtaaccgccc gcagttttac aaacgaacca tcttccagga ataaggtctg gtcaggctga
      541 taagcatata ccgcgctcca tggattgtat gccggtacct tgctatagtc gccctgtacc
      601 ttcgaccacc agctgatttc tttaatggcc ttgggatcat ctatcccttc cctgttggca
      661 aaatcgaaac ggttggctaa cgcctggttt ataattttac ggccaaaagc ataattcacc
      721 agtgcattca actcccagtc acgatagtaa aaagtattcg taaagccccc cgtcaccgca
      781 ggtgataaac gccctttcat gacgcggtct ttgtcgttaa tatcataatt gccatccagg
      841 tctctccaac ggggatcgcc tttgcgcaag gttacaccct ggtaggtcat cttcttaccg
      901 gtggcaggat ttacaggaac atctccatct gagttgtaaa tgccctcgtt gatcaagagc
      961 caatagcgat cggtgggttt gcccaccagg aagcggcgct ggctgatcac caggtcggta
     1021 aggccatcgg gcaatgccag taatttattt tggttggtat atgcactgat gccggttgtc
     1081 cagcggaact tttctctgcg tatcacatct gcttccaccg ataactcata gccatagtta
     1141 cgtatggtca tcccattttt cacgatacca gtgtaccctt cctcttccag cgttggaatt
     1201 ttcaatacaa ggttacggtc tgttttagca tatacatcca gggaagctct tacccggtcg
     1261 tggaataagc cgatatcaat accaccattc agttgctcta ctaccggcca ggaagtaccg
     1321 ggaacgatat accccgtggt atagccggca ttgattaccg ggaatgcgtt gtaggtcgac
     1381 atattaggca ccccattcca gcccgcgtct acattgtata ccggccctcc cctgtaaaat
     1441 tcatccatca gcaaacggcc cacccggccc caactgcccc ttagttgcag gttactcagc
     1501 caggttgcat ccttcaggaa atcttcctgg gatattttcc aggaagcaga tacggtagga
     1561 gataccagcc agcgatgagc agcatccagg taagaagtac cgtcccttct cacgtacagg
     1621 gacacaaaat atttaccatc aaagttatag ccgatgttgc tgtaaaaaga ggcaagcctc
     1681 gactgcgtaa aatctttggt attaaacatt agccggaaat tgccaaagcg cccttccttc
     1741 tgatcgtctg atccgggttg gtatatctta atataatcgc tggaaccttt ataggcgcga
     1801 ccatagtcat agcgccattt gtcccattgc ccgtattgcc ctaatgtcac ctccaggtga
     1861 tgtttccctg aaaaagtatt ttcataacgc agcgagttgt ccagcaccaa ccttttgttt
     1921 aatccgtcga agttggacac ataactattt ccttctccca gcgaggtggg tacaaaatag
     1981 tcgcggaaat tttgcccata gtcaatggcg aaacgtgtat tccaagtgaa atgactggca
     2041 aagctgtatt tcacattggc gataatacgg gcggaattat ttttatttcg gttaatcgta
     2101 ttatccaggg ctgtgtaata ctgttgcagg taggctttgt tgggtgatag cggcgagctg
     2161 tagttaaaca ggtaatcttc atcgccggcc cggtcccgga taaactcatt gcgtttgcgg
     2221 ttcaggttag ccacggctac ctgtgtggta aacaccaggt ttttcagcgg ttggatgttg
     2281 ataccaaagt ttacatcata gcgccggata cccgttttgt cgtatacgcc ctgttgcgat
     2341 gattgcccta tgctaaagcg gaagttagcc aggggcgtac caccgcttac agatgcctgt
     2401 ataccatctg taaaggcatt cctgagaaac aagtcatccc agttggcagg gccaaaatac
     2461 ctcgcctgtg acgagtcggc caggtagcgt ggaaagctgc gccactgtgt ttcattcgca
     2521 tacttttgat aaaacggtaa cctgaaatcg ctctcgtatt ttccgttcac agcatctacc
     2581 gacgggcgta gcgacaagcc ggcataagca tttacagata cctgcatctg ccctaccctc
     2641 ggtgctttgg tggtgatgct gataacaccg ttggccgcat taggcccgta ctgcgcgctg
     2701 gcgccaaagt ctttcaacac ctctatccgc tcaatatcat ttacatccag gaacgataat
     2761 aagttggttt ccgttcccat ccggttaaag tcgaagcgct ggatatcata ggcaaaggca
     2821 tggtccatga ttaaaggcac accatctacc acgtaggccg gctgtgcata aaagatatcc
     2881 cggttactca gcaacagcga agacgtcccc ctgataaata cgctgttgcg cttacctggc
     2941 tcggcagacg gtgttcgtat atccactccc gttactcttc ctactaacat ctggtctacg
     3001 ctcacataag gcaatttctt tacctcgccg acatccacgt tggacaccgc gccattgatg
     3061 ctacgtgaca gaaaaagttc gttgttaggc aggtagccaa tcgtatcccg tttggtgctg
     3121 gttacccttg aaagaataat ggaatcagca ttggccgtac tactggagtc tttgccagta
     3181 ttcctataca acgtgcgctg ggcctgtatt tccaaagtac acaggcataa gaaaaacaaa
     3241 aggtaaatgt atttcataca agcaattttt aggaatgcga cttccagggc gcaaaatcat
     3301 tcttgcacca acaatagttt tcaaatacat aaacaggcat aacttgccca ctccctttgc
     3361 agggaaagga ctaacaccgc taaatgaatg cgccaacagt gactacaaca ggataatagc
     3421 cgtcagcccg catgcaaaac atcgcatacg cgcaacaggg caatactagt aatctgtgga
     3481 aacaccgcgc caggatgcta ggggcatcgg gctacccgga caggttgcaa tgaataatga
     3541 ctcatgggaa tttttattta acgtgaaatt ttaaacaatc tgtcgctctg gctttcaata
     3601 attgctaata ccaagacacc gcgggtaact gtcgcaaacg tagggtctct ccgtctatca
     3661 gtactatcaa tgctctttaa attttggttg tcgctacaaa cgctactttt caaatgtaat
     3721 tagctaaatg gatttttcat agcttttttc aatttatttt aaaaaaaata ttgaaggtcg
     3781 ccacacctat tttttaaaag gggtcatcac gatgttatat ctgaaatcaa gtaaccagct
     3841 aagaacgctc taagaaatag tcaacaccta tccttccccc accaaatacc agtagggtaa
     3901 ataacatcac caggtaatac aatggtattt catagccgtt gtccccggcg gcaaacccat
     3961 tgctccagtg aacggtagca atagccacca ccatactaaa cataagcggc agtgtaatat
     4021 agcgcacaaa caaaccaagg gttaacaata ccacgcccgc cgcctcggta catcctacca
     4081 ggtaagcgct gatataaggt aaagggatat gcaattgttt aaaccaatcc cctataccat
     4141 gtatatcgct ccacttcatc ctggccggca agtaaaaacc ataagccagc accagccgca
     4201 taaataatag tggaagatcg ctgatcaccg ataaacggcg cgccatccgg gcatatgtac
     4261 gcataaatta tgattgaaat cccaatacaa aatgttgctg ttgcatctcc ttcaaaaatg
     4321 ccagtgtatc cgattccagt gtgtccgttt ccgttatatg tagctgcggg gcataatcca
     4381 gtatatccct taccgttatt ccctgggcca actgctctgt taaaaatgcc agccagggcg
     4441 ataaatccgt aaactggatg ctgcctgttt ccggatgacg gtataataag gcgaagtaaa
     4501 cacctttacg ggtcatcagc tccctgcgct ttgctttcag gtgaacaggc cagctaaatg
     4561 atagcagccg gtgctcctgg ttcaatacca gtggtgtatc caaccaattg ccttccgtaa
     4621 gatacgccgg cgcaggaata tcctccatgt tatataattc catttccgcc cactcaaatg
     4681 ccagcaggtc attcaggtaa ggaatatcgt attgctcatc ccagctatgc tctaccgcat
     4741 aggtataaaa ctccaatggc aatttccaaa gctggtacga ttgacaggca tggtgcgcaa
     4801 aaaaatcctt caccatctta tcccacttgc gcgagggaat gttattaaag gcaataggaa
     4861 aagcattttc catggtatcc cggatattgt tgaataccag gcgccggtag tgtaccaacc
     4921 tatcggcaac tacgccaggc agctgtactt ttttgccggt tctgcaccag tcagaaaaag
     4981 tttgctgtat atgataagtg tcaggcaaca agttcatctt tcaatttcca ttgtttgtga
     5041 caaatacttt tcaatcttga gagttcgccc tgcaattcga tcatctccgg aatattaaaa
     5101 tctctttcca gtaacaccgg taccggttgc agatgcgcca gggtccattc aaacaggtca
     5161 tacaccggat ctataatagg ctccccatgt gtatcgataa tcaggtcggg ggctacctgt
     5221 tcgtgccctg ccatatgtat ataggctaca ctgctcagcg gcagttgctg aataaacgcc
     5281 tttgcatcat actgatggtt gaaagcattt acataaatat tatttacatc caacaataac
     5341 tggcagccgg aatgctttac cacttcattg ataaaatcaa tctcactcat ttctgcagct
     5401 accggcgtat aataagaaac aatttccatc gccagcggac gctgcaagta atcctgtacc
     5461 tgctgtattc gcgatacaat atgccgcacc gcatccatcc ggaaagggat gggcaacagg
     5521 tcatacatgt gtgcattgtc gcatttggaa taactcaggt gctctgaata cagctgtact
     5581 ttatactcct ggagaaatgc ttttacatac gcgaggaact ccttatttaa ggcatcgggg
     5641 ctaccaatcg ataatgaaag cccatgacac aacacaggat atttctccac cacccggtgt
     5701 aatatcttcc tccaatagcc tcctatgttc atccagttct ccggcgccaa ctcaacaaaa
     5761 tcaggcctga tatgttcccc gctgataagc tcctcggcaa attctctcct gaaaccaaca
     5821 cctaccatga ctatacgatt tagggtgttc aaaaatgagg aaaggctgac taaatgttat
     5881 atcagccttt cctacccgta aaaattactg gccagacttt gttgtgtcag gcttggtttt
     5941 gtccttgcct ttcttctcgc cctttttgtt accgcattta ccttctccac atttgccttg
     6001 accacatttg ccgtcttttg atttaccggc agatgcactg tctttctttg cgccgcagtt
     6061 cagctcaata gcattggctg ctgtaccgga agtacccgtt aatgcatttc taacagctgc
     6121 accagaaccc aggttagtgt aactaacggg tttggcagat acctgcaggg atgctaaacc
     6181 catgatagcg ccggctacca gtgaaccgga aaacagtaca ttcttgttga tcgctttgtt
     6241 gtttttcatg atcttagaat ttttaaaaaa cggagtgaaa aaagtatgta tgttgtttag
     6301 acgtagcgct gaaatcttcc ttacaggtcc ttatcatttt ttaaatatgc tgccaccaat
     6361 gcctcccact gctgctttac ctgctcgtta ggagcagtaa aagcttccct gtattcctgt
     6421 aattgccggt gcataatagc tgtctgcttt acatatctcc tgcaatacac acatagcagc
     6481 aaatggaatt ttaaccccaa tcgttgcatc caggtaagcg gctcctgctg taaacgtttc
     6541 tctaccagca tcgtcacatc tttacaacag ggcatcaggt gatgtaaatg ttttcccatt
     6601 gtcaattact gaaccaattt ttttcaagac atgcccttaa ttgtaaccgg gcccggtgaa
     6661 tgatcaccca gtagttagac gaggtaagcg aaagatcctt acagatatcc gcggattttt
     6721 tttcatcgag atatttatgt tgtataaccg ccttgcctaa actggttaat ttatccatgc
     6781 aggtgcgtaa tatccggaaa aaatcggctt gttctgcttt gtcattgata tcagtagtcc
     6841 atggtcgggg agccatctct ttacgccaat gtcctttctc attaaaaaaa atcagctgct
     6901 gatcacgggc ttccatatca agggttgtta ttgcagcttt acctgccata cgaaagtgat
     6961 catttatttt gttcttaaga atagccagca gccaggtctt ctctgaactc tcgccacgaa
     7021 attggtgcat agcctgcaaa ccactaagaa aagtgtcttg taccaggtct tgtgccagcc
     7081 cggtatctga tacccggcta caggcaaatt taaacaattc gtctgcatat aacttcaccc
     7141 acaccgttgg attacaggtt gtcataactt ttagtactat tgactgcgat ctttctgcct
     7201 ccttatacac ctgctatatc gctaaagaaa gcttacggta atatacctgt tttggttttc
     7261 tcctgcaccc aaaaaaatgt taaaggcgga taaccggcgc caaaggaatg gtaaaaggca
     7321 atagggggcc ttactactat tcggcgtttt atagtaattt tgacaagtac ccaatgaaat
     7381 atgaattaaa ctcggcccat gaaaaatgaa atgtcgcctg taacgtacac ttactttgtt
     7441 acactattaa aagcgtatct acgtggtact aaaacaagac aggagctgat cgaagagctg
     7501 cgtggtgtta ccccatggga ggaaaaagag gaaaatatac ataccgaagt aagccgcctg
     7561 ctgtttcagg ccgctaatga ggtaaatgaa aatttctacc aggatatcgt gagcgccatc
     7621 acccatgcta ccgataccgc tcccacccgg gaaggcgtca tccaccagct ggaagccgtc
     7681 ctcaccggct tcataacacc cacccacctg taccagtggg ctacctggca taatgaaccg
     7741 gatatggaag cagtttcgtt ctttaacgac attgcggttg actatttctg cacccagctg
     7801 ttgccggcct cttttgagga gttaacactc acagactata aacaggccct gaaaatcttc
     7861 cggtcgcacc atcacgacag cctgaaagat aaagtggccc tggtactgat ttcccagaag
     7921 gaaagacagc gcttcctgtt ctatctcagc gattatatcc agggacatag ctcccccgaa
     7981 caactggatg tatatctttt acacaaattt gggatggacc atcactcctt tccttatatg
     8041 tcagcgatct ctgccatgat gcatgaaccg gctaaattac cggcactact gcaaatggcc
     8101 gccatgagcg aataactcaa ctcaccatca ggctacaccc tctcagcgcc gagttatcca
     8161 atcgacccag cacttcaaac aaaccattgg cgtgtatccg tccaatatct tcagtcgcga
     8221 taaatgcaca ggaatagata ttggccaggt caataacatt aatgaccccg gcgcctttac
     8281 cggcgcttag ctgaaacgga tcattctcgt ctctcagcaa aatcttcatc cagggagggc
     8341 tagcaaacaa accattccct ttggaatagg cctgggataa cagctctgtc atcccatatt
     8401 cggcatgaat aacggaagcg cccaaacgtt cctgcaggaa ggcatgtact tcctggcggg
     8461 tccattcttc ccggcgtccc ttcattccgc ccgtttccat tacaatggta tggcgcagat
     8521 ccagggaata ttgctcggca aagtccagca gcccgaaagt gaccccaatt aacaataccc
     8581 gctgtcccct ggcctccagc gcccgtagct gatgatacaa cttatcatgt tcatacagat
     8641 aaaagccgct ctccggatga ccgctgcgga ttaccatctc ctgcaccatc ctcaccagcg
     8701 atgaatgttg ccgctccagg taggaaggca gcaaccccag gatcacataa tcgtctaccg
     8761 ggccataaaa ctgttcgaag gccgtcatga aactacgggt ataaatggcg gattccttca
     8821 ccaggtgacg gctgttgatc gtttgagtgg taccgctgct ctcaaatagc agctccggct
     8881 caaaaatgcc gctgaccacc gtatgggatt taaaaaattg tatcggcaga taaggaattt
     8941 ccaggatgct cttcacggaa gccggtgcaa tgtgtaaggc atccgtatag gcccggtaca
     9001 ggtcattttc ccggtactgg taacggaaaa gctccagggc ggcggcttcc agtccgttgt
     9061 cctgcagtga aaaaatagtg tccggtgata ccacagtcat gtatagctgg ctttaaaatc
     9121 tgacaaagtt agggagaaga ataaatctaa cgccagtaag taacaattgg catgaaaaaa
     9181 cgtttttagg aagaagggta gagatagctg aatatttgta tatttcctaa attaatgtag
     9241 gtttgtttta tgaagaaaat tctgtttttg ttcctggtgg ccggattact ttacgcctgt
     9301 aaaaaagata agataggtag caaacctatt ctcaccttca aaggatatac agtagacagc
     9361 gttaccagca acctggataa gatgactgtt attatgaatg ttcgcgatgg agatggagat
     9421 attgaagaca cgctgtggat tgctacccgg tatagaaatt ctggtacgtc cgacaccctg
     9481 tattccgtta aacaaatggg cagcattggc gccaacaaag gcaatagcgt aaacgccgac
     9541 gtatatatca acctcctgcc tacagagttt aaaatatcac acccctttgt tgcagacgac
     9601 agtattcact ttgtagtatt cataaaggat aatgccggta acttcagcga taccgttgga
     9661 accaggggca ttccttacaa tgcacaataa ctaaaatatc ttacatttac gatattgcag
     9721 ggattccttt aataaaggaa tccttttatt tttagtttta ctactcattt ctagcatatg
     9781 gacaaattag aggaattaca gtcgaagata gccgaagcca tgttgggtgg cggcgaagta
     9841 cgtatcgctt cccagcataa aaaaggtaaa ctcaccgccc gcgaaaggat acaactgcta
     9901 atggatgaag gctccttcga agagctggat atgctggtaa caaaccgcaa ccggggcctg
     9961 accgcagacc aggaacaatt cctcggcgat ggcgtggtaa ccggttatgg tactattaat
    10021 ggccgcctca cctacgtatt ttcccaggac tttaccgttt acggcggcag cctctccgaa
    10081 ccccatgccc gtaagatctg taagattatg gacctggcca tgcaaaatgg cgcccccatc
    10141 atcgggctca acgacagcgg aggcgcccgc atccaggaag gcgtggtaag cctgggtggc
    10201 tatgccgata tcttttaccg caataccagg gcttccggcg ttatccccca gatatccgcc
    10261 atcatgggcc cctgcgccgg cggagccgta tattcccctg ctatcaccga ctttatcctc
    10321 atggtggaac aaacctccta tatgtttgtg accggaccta acgtggtaaa gaccgttacc
    10381 catgaagaag tgacttcgga agaactgggt ggcgcccaaa cccatgccgc caaaagcggc
    10441 gtaacgcact tcgcctgcgc caacgaggtg gaatgcatcc aatatgtaaa gcaactgctg
    10501 agctatatcc cgcaaaactg cgaagaaacc gcccccgtat acccttacga accaggcaat
    10561 gaacgcaggg aagccctcaa caccctgatc ccgctgcatc ccaatcagcc ctacgacatg
    10621 aaagaggcga ttgaacagat cgtggatgaa ggcagcttct tcgaagtaca taaagacttt
    10681 gcagaaaaca tgatcgtagg ctttgcccgc atcgccggca gaagcatcgg tatcgtggcc
    10741 aaccagccag cacacctggc cggcgtactc gatatacacg cctccgtgaa aggcgcccgc
    10801 tttacccgct tctgcgatgc cttcaacg
//
