LOCUS       NZ_CP051206            23183 bp    DNA     circular CON 09-DEC-2024
DEFINITION  Dolichospermum flos-aquae CCAP 1403/13F chromosome, complete genome.
ACCESSION   NZ_CP051206
VERSION     NZ_CP051206.1
KEYWORDS    RefSeq.
SOURCE      Dolichospermum flos-aquae CCAP 1403/13F
  ORGANISM  Dolichospermum flos-aquae CCAP 1403/13F
            Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Nostocales;
            Aphanizomenonaceae; Dolichospermum.
REFERENCE   1  (bases 1 to 5151752)
  AUTHORS   Wu,V.
  TITLE     Genome-Wide Identification of 5-Methylcytosine Sites in Bacterial
            Genomes By High-Throughput Sequencing of MspJI Restriction Fragments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5151752)
  AUTHORS   Fomenkov,A., Anton,B.P. and Roberts,R.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2020) Genome Biology, NEB, 240 County Rd, Ipswich,
            MA 01938, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 04-DEC-2016
            Assembly Method                   :: HGAP v. 2.3.0
            Assembly Name                     :: Afl_HGAP3_4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 114.08x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012516395.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:24:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,987
            CDSs (total)                      :: 4,921
            Genes (coding)                    :: 4,734
            CDSs (with protein)               :: 4,734
            Genes (RNA)                       :: 66
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 187
            CDSs (without protein)            :: 187
            Pseudo Genes (ambiguous residues) :: 0 of 187
            Pseudo Genes (frameshifted)       :: 35 of 187
            Pseudo Genes (incomplete)         :: 162 of 187
            Pseudo Genes (internal stop)      :: 14 of 187
            Pseudo Genes (multiple problems)  :: 21 of 187
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:01:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2895746
            Orig. end                         :: 2918929
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP051206.1.
            Bacteria and source DNA available from CCAP 1403/13F.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23183
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="9"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23183
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23183
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13183](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13183
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            467..832
                     /gene="folB"
                     /locus_tag="HGD76_RS14120"
                     /old_locus_tag="HGD76_14125"
     CDS             467..832
                     /EC_number="4.1.2.25"
                     /GO_function="GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081155.1"
                     /locus_tag="HGD76_RS14120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14125"
                     /product="dihydroneopterin aldolase"
                     /protein_id="WP_168696166.1"
                     /transl_table=11
                     /translation="MDCIHLTGIRGYGYTGFLPEEQALGQWFEVDVKLWLDLFQPAKTD
                     NIEDTIDYRRVISLVQKLLKTSKFALVERLAGAIADGILEDSDGISQVQVILSKTAAPI
                     PDFSGKISIELTRSKLQ"
     gene            986..1480
                     /locus_tag="HGD76_RS14125"
                     /old_locus_tag="HGD76_14130"
     CDS             986..1480
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017745746.1"
                     /locus_tag="HGD76_RS14125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14130"
                     /product="hypothetical protein"
                     /protein_id="WP_168696167.1"
                     /transl_table=11
                     /translation="MKITFTDREMQRAWRENSSAYHNHNGVRTNAHRLLLFYAVECGLK
                     AVLMKKKKVNRTDLYPEILKKGHDINGLLECLYPGNNSLQIWKLPKQLFIQDIQDNSYV
                     KIKQERQLTPDDINQIWRYGGKFILKKDESENKREKITDEDIEKKLLNIVELIKKELQG
                     L"
     gene            1477..4275
                     /locus_tag="HGD76_RS14130"
                     /old_locus_tag="HGD76_14135"
     CDS             1477..4275
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081157.1"
                     /locus_tag="HGD76_RS14130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14135"
                     /product="ParA family protein"
                     /protein_id="WP_168696168.1"
                     /transl_table=11
                     /translation="MKDFKLLTWLDIRRIFRRKTNYGTNLPENIVSIRCFSDAVEINIS
                     DENCINKVNDVLKEWFEDSYQQEESMIQLDVSNATLPVEFISEEEPYITDIEVRPFWEE
                     IAYLESDSETETAIKKIVKLPEPYTEKLSLIAFYSFKGGVGRTLNLAAHLFALLDRAKE
                     LNKSIKVLVIDADLEAPGLTYWNESSKRKQPEVSFINFLEIYHYSPIDREEALALFANE
                     VKKSVKHEGNSQVYFLPAFLKDNELLDMPILPEHLVRGIDGTWEYGNAIHHLGEILGVD
                     YVFIDLRAGLSEISSPIIFDPRIQRFLVTTINDQSIRGTSLVLKQIGKVAPSKEEVNKK
                     IYYDPAIIISMLKTEFKELPNYINATTDLESNYVQSKEPTLIDTRLNTQETDFNEKLLY
                     IHNWEDARSKLKETTVIEKAIDWASQQLINAEKEVQTTKDKGDIKSRQEQQVTRLRDLC
                     QKYELAESGEGEDLLITEPLQNLATNFRDELPHVISIGAKGAGKTFNYIQLSRFKYWGK
                     FLNSIDKNETSSIQTKTYILPFLESSNLKNKAKTVISEARNEVRAVLGVNVPEFVHSEY
                     TDRIKTALTEQNWDELQWTKFWVNEIARAIAINQNLDTPNTLSSINQDLKNKGLKIIFL
                     FDGLEDIFPKIASNDQQQKALKTLIDDLPKKLSEIRQSHLGIIIFLRRDFLRYTITQNL
                     RQFENLYRSYDLSWNEDSFLKLVYWICSESNVIGAKKDSKDSIYSLSQENLVAELEKLW
                     GKRLGAEKSKEAYTASWVFAALTDFKGRLQARDIVRFLYYAAKITVDNAKEIQFEKWST
                     SRLLPPQAIRRALKPCSEEKVKEAKEEYPTFKTWVEETLPPQSERKIPFAVEKFNIDQQ
                     TMGMLEEMGVIYEDTAKEDIDRFYMPEIFREGLGFSGQGARPRIVALKRRVLGKGIFAN
                     LQ"
     gene            complement(4314..6467)
                     /locus_tag="HGD76_RS25435"
                     /old_locus_tag="HGD76_14140"
     CDS             complement(4314..6467)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015207913.1"
                     /locus_tag="HGD76_RS25435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14140"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_168696169.1"
                     /transl_table=11
                     /translation="MSQTAPISPDNFTNVPIPPSKQQKGKKPIPLLLGLLVVGGGISYA
                     VWRTQPQKAVDTLKLSGRIEGYETEIGIKRSGRIESIAFREGAYVKKGQELIKLDDSND
                     QLLQEQLRGTEARITSAQSDEQQAIADVDRVQSEIEQINSQIREAKLNLQQSEGDTQGR
                     IQQAKSNVAAAKTQLLQTQAQVKQTEAEVKLARINRDRYGQLIKEGAINQQQFDQSQTT
                     LDTAIATLEARQASVNATREQLSAIQGALTQTKTTGFNPGIPNAQLIHEIGTPAALRNH
                     LGLHRLEVKTANLEISEKILLQNLHTNVVDVQTFGDSEALRRNRLDVLVEDITIGETQV
                     NELLKQYDPNIEHGEPTLENVFVTRLRQQGSAPPFLQFPRSRGGNKSQEINENIHREKN
                     SSLLPITNYQLPSSQIAIYANNLNRVFGKFQAVKSVNIEVRYGEIFGLLGANCAGKTTT
                     IKMLCGLLAASGGEISLGGETGNLRSAKLRKRIGYMSQKFTLYDDLTTLQNLEFYSGVY
                     SVTRKLRKEKIDWVISTCGLEGQENMLTGQLPGGWKQRVAFGASVMHEPDILFLDEPTS
                     GVDPLARRQFWKLINDFARNGTAILVTTHYLEEAEQCNRMSFMVAGEIAAEGSPSYIKD
                     SQPGKLIEIIVNQNQAASKLLKQQFDAWRVSIFANSLHIVLDNPEVAIAQVMQLLKSAN
                     FTILGLVFFNVSRRILSKMQISD"
     gene            6776..7897
                     /locus_tag="HGD76_RS14140"
                     /old_locus_tag="HGD76_14145"
     CDS             6776..7897
                     /GO_function="GO:0004325 - ferrochelatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006783 - heme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015213969.1"
                     /locus_tag="HGD76_RS14140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14145"
                     /product="ferrochelatase"
                     /protein_id="WP_168696170.1"
                     /transl_table=11
                     /translation="MVATPEKLHATHSHEHIPSKDRVAVLLMGYGEVESYEDFANYNEQ
                     ALNLLTAKFAPVPTWIYPPLAKLLALFDRHEWGHTHHDFISPHNAIFERQRAGIEHELQ
                     HKWGNGVQVFKAFNFCAPFLPNQVLAEIKDQGFSKLLIYPLLVVDSIFTSGIALEQVNN
                     ALVELADGDEHWIKAQRYIPSFYNEPKYIDLMAHLVEEKIHTDLATGYLPSQIGIILMN
                     HGCPHKAKGFTSGIDESQAMYELVRNKLINNYPLISVGWLNHDTPLIEWTQPNATVAAQ
                     NLIQLGAKALLFMPIGFATENHETLLDVHHIIHDLEKQHPDVDYLQMACVNDDPQFLAM
                     VAEWANAHIAELMETEGMAVNSESAITHHHHHH"
     gene            complement(8198..9892)
                     /locus_tag="HGD76_RS14145"
                     /old_locus_tag="HGD76_14150"
     CDS             complement(8198..9892)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0046930 - pore complex [Evidence IEA]"
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017323814.1"
                     /locus_tag="HGD76_RS14145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14150"
                     /product="iron uptake porin"
                     /protein_id="WP_168696171.1"
                     /transl_table=11
                     /translation="MLKIFLGLVLATPVVLISPVAWASEIAENDDLAQVTSVSQLSDVQ
                     PTDWAFSALQSLVERYGCVAGYPNGTFRGNRAMTRYEFSAGLNACLDRVNELIATATAD
                     AVQKEDLATIQRLQEEFTSELATLRGRVDAVESRTATLESQQFSTTTKLSGEAIFAITD
                     VLTGDSDPFNVGVPRNSTILANRVRLNLVSSFTGQDELKIRLQAGSTPHPQRAGGFRYG
                     ADPFLASLGSRQTTPEGGQTFNQEFPDTAGSVELGTVSYKFPIGKKIRAAVFANRGEHV
                     DYLPNVFSTVGDEDGGSGSLSTFAQYSPIYRLVSQGAGLGLNYQLNPAINLSLGYLAPN
                     ANSPEGLTPDSSNGTTAGGFFDGRYSALAQLSIQPTKNLAFGLTYVNGYTAGTPTFLND
                     VGTISANSPSLISDNARREINAYGVAGLWRVSPKFAVNSWFMYTNQQGKSAGTDNESAD
                     VYSYAITLAFPDLGKQGNLGGIVVGVPPYATRSGVVPLYRPFLGGASDVISTIPNRTTP
                     LHLEAFYKYQLNDHISITPGVIWLVAPNQTNNNPDVVVGTVRTTFSF"
     misc_feature    complement(9943..9958)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 23.84"
                     /tool="antismash"
     misc_feature    9946..9961
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: strong, score: 28.57"
                     /tool="antismash"
     misc_feature    9949..9962
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 24.5"
                     /tool="antismash"
     misc_feature    complement(9949..9964)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.82"
                     /tool="antismash"
     gene            10001..13183
                     /locus_tag="HGD76_RS14150"
                     /old_locus_tag="HGD76_14155"
     CDS             10001..13183
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015136860.1"
                     /locus_tag="HGD76_RS14150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14155"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_168697447.1"
                     /sec_met_domain="DUF4135 (E-value: 4.7e-125, bitscore:
                     415.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.2e-78, bitscore:
                     260.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVNCQDSAWFRAMSLKERIVANSEELGYDSELGYKRFQRWKSA
                     SSFANSSLFAQKLVTEGITEEEFCRILGQSVAPIPLSWVEEIQQIYEYLGEKDITTVLS
                     NSSLCTHPNFGFLKAIAPFLVQGMIKLEIGLNNIQNIPETLSDIHDVLLEGLPEKLLLM
                     LNATLVLEVNIARLQGLLTGDNAQERFYSFIQRLRNPEVQLALWQEYPVLARQVLEEIN
                     RWVENSIELIQHLSHDWVDICYQFQSPTKLGKLIKVNRGKGDSHNNGKSVTILTFASGW
                     QLVYKPRSLAIDGHFQQLLSWLNAKGFKPAFQTLQILNRDNYGWVEFVSFQECDSAEEV
                     ERFYQRQGGYLALLYALEATDFHFENLIAAGEHPILIDLESLFHPRSNYKGTAADTLDR
                     EIVADSVLQVGLLPQPVWGNTEAAGIDMSGLGGAGGQLTPEKVPKLVQVGTDIMRVERQ
                     QAVIAGSQNRPQLNQQEINVQEYTAAITEGFTAVYRILLQHRQELLNILARFAEDKVRV
                     VMRASRVYALLLRESYHPDFLRDALERDRLFDKLWIDVENRPQLSQIISAEINALWKSD
                     IPLFTTYPHSRDLYHQETGLHISNFFNQSGIELVHHRLNNFSEKDLQRQTWFIKAALAT
                     LEMSKTADNHQIRLGKKACNISTIIPTTKDQFLEIACKIGDRLELLAHNNGKFVNWMGL
                     SVTPNQQWTLAPLGTDLYAGIPGVALFLAYLGEITQNHLYTNLAQAAIKTLKQQLKRDS
                     IKFIGGFSGWGGIIYTYTHLGILWQRKDLIADAVALVAKIPPLISQDKQLDIITGAAGC
                     IGSLLSLYQIVPEQFILDVARQCGEHLLTQAQITDTGIGWISPAGGNQPLTGFAHGSAG
                     FAWALGKLAVTTGNQEFQTAATAAINYERSHFDPTTNNWIDLRIKEEKNSFMTAWCSGA
                     PGIGLGRLSMTENTPDLIMYKEITTAIQTTIKQGFGDNHCLCHGDLGNIDLLLIANSIL
                     NDPEIFQQTEKIASQILDDIQENNFLCGVPLGLETPGLMTGLAGIGYGLLRLAYPQIIP
                     SILLLEPPKQSS"
     gene            13216..15360
                     /locus_tag="HGD76_RS14155"
                     /old_locus_tag="HGD76_14160"
     CDS             13216..15360
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016873902.1"
                     /locus_tag="HGD76_RS14155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14160"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_168696172.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-35, bitscore:
                     120.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYPIILQHNEEDCGPACLATISKYYGQLFTITRVREASGTGQLG
                     TTLLNLKQGAQVLGFNARGVKAALELVDKKQIPLPAIIHWKGNHWTVLYGRKNQKYIIA
                     DPLVGVRTLTKEALLKGWTNSVMLLLEPRVDFLEQPDDRGKIGGFKALIQRFLNYRLIL
                     AEALLLNFVVGLLSLLSPFLIQILTDDVLVRGDTQLLTGIALGILTMSFISSCLQWVQG
                     NLVSHFAHRLELDLVWEFARNILRLPLSYYESRRSGEVVSRLRDIQTINQLVSQVGVIL
                     PSQLLIAITSLILMLFYSSQLTLVSIFVAMIMTFSTVLSFPSLQQKIRTVLGLASENQG
                     VLVETFKGALVVKTTNAAPEFWQEFQTRYGRQSNLMFLTVQIVLINTIFSNWISTAGGI
                     ILLWYGSILVINRELSIGQLLAFNSLNTNILGLVNTCVRFITDFARAQAATERLNEVIN
                     STPEFSEVSQKPFVNIPDNADLICKDINFHHAGRVDLLKDFSLTLPGGKVIAIIGKSGC
                     GKSTLAKLIASLYNSQSGNIRIHHYNLSDINPSCLRQQIVLIPQDAHFWSRSILDNLSL
                     GCPQVNFEQIVTACQVADADNFISKLPEKYQTILGEFGANLSGGQKQRLAIARGIVTNP
                     PILILDESTAGLDPISESLVLDRLLAYRQGKTTILISHRPRVIKRADWIVLLEAGQLKL
                     QGTPTELLSIAGEHLDFLIP"
     misc_feature    complement(15414..15429)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.3"
                     /tool="antismash"
     misc_feature    complement(15439..15451)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            15536..15760
                     /locus_tag="HGD76_RS14160"
                     /old_locus_tag="HGD76_14165"
     CDS             15536..15760
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019497585.1"
                     /locus_tag="HGD76_RS14160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14165"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_168696173.1"
                     /transl_table=11
                     /translation="MSNLDIIRAWKDEEYRNSLSAEQQEQLPANPAGLVELNDEDMSSV
                     SGGCTTCGNPLHTLFWTCKAVSSPFDTIA"
     CDS_motif       15536..15679
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSNLDIIRAWKDEEYRNSLSAEQQEQLPANPAGLVELNDEDMSSVSGG"
                     /locus_tag="HGD76_RS14160_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15680..15760
                     /prepeptide="core"
                     /locus_tag="HGD76_RS14160_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="2688.1"
                     /monoisotopic_mass="2686.3"
                     /core_sequence="CTTCGNPLHTLFWTCKAVSSPFDTIA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSNLDIIRAWKDEEYRNSLSAEQQEQLPANPAGLVELNDED
                     MSSVSGG"
                     /leader_location="[15535:15679](+)"
                     /alternative_weights="2706.1"
                     /alternative_weights="2724.1"
                     /alternative_weights="2742.1"
                     /alternative_weights="2760.2"
     misc_feature    complement(15826..15846)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.32"
                     /tool="antismash"
     gene            15837..17330
                     /locus_tag="HGD76_RS14165"
                     /old_locus_tag="HGD76_14170"
     CDS             15837..17330
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017315237.1"
                     /locus_tag="HGD76_RS14165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14170"
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="WP_168696174.1"
                     /transl_table=11
                     /translation="MNNTIPNFLPTAKSDEYLPSIGIWTRLGGLFLVGVFGASVTISTF
                     TKYQQTVKASAIVRPTGEVRIVQTAIEGTVKKISVKENQLVKKGDVLIILDDIQLQNQK
                     NQLTVNIQQSQLQIRQLNAQIAALNRQIATETERNKRIVASAISEVQRTKRDYQDRKVA
                     VSSEWQEAQANIKIAENELLQVKSELQSIQANLESAEAGLKAAIVKRLRYEDIAKSGSI
                     SQNQLEEVQLAATQQAQIVESQKATLASQKQVIQQKQQVLTSAIARSKKAASSLNPSNA
                     VIFISEEKVATERANGKTNLARLQQEKESLIQGKIEIQNQINNTEKELQQLLTQIQKTV
                     IRASATGTILKLELRNSGQVVNLGSAIAQISPSYTPLVIKARVAAADISKVFVCNSPEV
                     VSCRKGKVKMRFSSYPYPDYGILIGAVRSITADAILPQDNITAEGYYEVTIEPENLYLQ
                     RDLQQYPIQAGMEVVADIISEEESVLTFILRKTRLLTNL"
     gene            complement(17533..20382)
                     /locus_tag="HGD76_RS14170"
                     /old_locus_tag="HGD76_14175"
     CDS             complement(17533..20382)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015083505.1"
                     /locus_tag="HGD76_RS14170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14175"
                     /product="zinc-dependent metalloprotease"
                     /protein_id="WP_168696175.1"
                     /transl_table=11
                     /translation="MNKFTFALILFNSLFVSIETANAQSLINNPRNSDIEIERQTTNVD
                     KIVQQLKLPSSKIAVIDQNNQVKIQNFVWVFKDLKQVGKQPFLQVKKEIEKPKAKPESK
                     SPKEDELEDFTEVTKDTQKSEGIFTIYRHKHKNKIYLEIKPEQLQKNFIANSTLESGIG
                     EKGIYSGMPLQDFLFYFQKVDNQIQFVVRNVNFRTREGDPQARSVARSFSDSVLYTIPI
                     KSINSQGKTILIDLGDLLLTDLAGLSTNLELAVSPDQGYLGNAKVFPNNLEIESIFNFA
                     NGGKNSDVLPDSRGFTLKVHYSLSELPKTKYQPRLADERVGYFLTAYQDLSKDERRDTF
                     VRYINRWNLEKQDPTAAISPPKKPIVFWIDNAVPLEYRQSIKEGILMWNQAFLKAGFKD
                     AIQVQQMPDNATWDPADIRYNTIRWINTVDGFFAMGPSRVNPLTGEILNADILIDGSFV
                     RLLKNDYRQIIQPQNSQTSTSLSTLVNNGRLCGKGNQKSPKSLGNLSKLATDYDLCYGM
                     EASNQLAFGSLAMSMLGNTTPSPEQLKDYIHQYLRLIITHEVGHTLGLRHNFRGSTLLS
                     PEEMNNPEITQTKGMTASVMDYIPPNIAPNGVKQGDYFPQQVGPYDEWVIEYGYTPSQA
                     STTMGEKSFLAAIAGKSNQRELSYAPDEDLSNSDPTVNPWDHSSNVLVYSHSQLANARR
                     MWERLNQGYAIDAENSSDVEERFNTILRNYLQNLYYTSKYIGGQSFYRVKPNDTKGQLP
                     FVPVPVEQQRQALMTMQKYVFAEDALKFPPELLNKLVPSRWLHWGTNIQVGRLDYPIHD
                     LVLLVQTAVLRDLLASDRLTRIKDLELKSASGKSLTLPELFDTLQSGIWSEVLQPKGKL
                     QISSLRRGLQREYLNVLMGMVLRKEATPEDARTLAWYKLKQLNNQLRRVNSEDEYTQAF
                     LLETRDRIEKTLNAPLVGN"
     gene            complement(20486..22546)
                     /locus_tag="HGD76_RS14175"
                     /old_locus_tag="HGD76_14180"
     CDS             complement(20486..22546)
                     /EC_number="3.1.13.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0016896 - RNA exonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA]"
                     /GO_process="GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012411239.1"
                     /locus_tag="HGD76_RS14175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14180"
                     /product="ribonuclease catalytic domain-containing protein"
                     /protein_id="WP_168696176.1"
                     /transl_table=11
                     /translation="MDKGTLVEFRVKGDRRLGVIDRPDGKTSWFVVDERGQSHNIKNNQ
                     FTYTVNGQTYKPGEIAEFLSQVQPYLDPSSLEIAWELLIEDGETVTPSQLANLLFSEST
                     SPQCYAAHCLLSEDKLYFKQKGDAYEPRSAAQIAERKHQIQVESQKAKGQQEFLARIEQ
                     ALQGQVVEWQRLDRQRLDALEKYATLLADVVMLKVNYDSLARACPPPASVLETMNMLGR
                     SATPQAAFQLLIDLGLWTSHENLFLRRSSISVQFPHQVLEVAQECWDFPPTDLDTNRLD
                     LTHLKVYTIDDESTTEIDDGLSWEILADGKERLWVHIADPTRLLMPDDELDLEARKRGS
                     TVYLPTGMIPMFPEVLATGPMSLIQGKVCCALSFGVILDAVGAVEDYCIHTGLIKPTYR
                     LTYQDVDEMLELGVQAEPEIEAIANWAKIRKTWRYSQGAISINMPEAMIKVKDDDINID
                     VLDDSSSRQLVAEMMILAGEVAARYGQTHNIPLPFRGQPQPELPPEEELLLLPAGFVRS
                     CAMRRCMPKSEMSITPVRHAGLGLDTYTQATSPIRRYSDLLTHFQLKAHLRGEGLPFSA
                     EQLKEVMMTVSSITQEATMVERQTNRYYALEYLRRHPEQVWQVTVLMWLREDSNLGLIL
                     LEDLGLQLPMSFRRSVSLGENLLVKVSLADPQKDMIHFQEIMYQEAQSVTN"
     misc_feature    22782..22795
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.54"
                     /tool="antismash"
     gene            complement(22845..23060)
                     /gene="rpsR"
                     /locus_tag="HGD76_RS14180"
                     /old_locus_tag="HGD76_14185"
     CDS             complement(22845..23060)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019490626.1"
                     /locus_tag="HGD76_RS14180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_14185"
                     /product="30S ribosomal protein S18"
                     /protein_id="WP_015083502.1"
                     /transl_table=11
                     /translation="MSYYRRRLSPIKPGDPIDYKDVDLLRKFLTERGKILPRRITGLTC
                     QQQRALTLAIKRSRIVALLPFINAEG"
ORIGIN
        1 gataatctaa cattcccaca tctagagaag gtgtagctaa ttccccttgc caattgggat
       61 aattaccgta taattttact tggtcaatag tttgtcctga atgacaatct cgtaattctg
      121 ctggtctgtc agtggttaat attaacaaag ggacgcgact ttctctagct tcaattactg
      181 ctggataaaa atttgccccc gcagttcccg aagtgcaaac taatactaca ggtttccccg
      241 ttgcttttgc ttgtcccaag gcaaaaaaag ccgccgaacg ttcatctaaa atcggaattg
      301 cttcaatatg cggtatttgt tggacaaaag ccacagttaa tgctgtagaa cgagaaccag
      361 gacagataac agcgcatttt aaacccaaac gtttgagggt ttctgttaat acataacacc
      421 aaagaagatt aagattatta aaagtaagtt gcattgatta gagattatgg actgtattca
      481 tttaacagga attcgcggct atggctatac tggattttta ccagaagaac aggccttagg
      541 acaatggttt gaggtagatg ttaaattatg gttggatctt ttccaacccg ctaaaacaga
      601 taatattgaa gatactatag attatcggcg cgtaattagt ttagtgcaaa aattgctgaa
      661 aacctcaaag tttgcgttgg tggaaagact agctggggct atagctgatg gtattctaga
      721 ggatagcgat ggtattagtc aagtacaagt tattctcagt aaaaccgctg cacctattcc
      781 tgattttagc ggcaaaatca gtattgaatt gactagaagt aaacttcagt agcaggagtc
      841 acgcagaaat atttggttta ttaaaactgt atcaattatg gagtgtttga cattaatgca
      901 ggatgagttg aagtataggt atgagcggtt aataggtggc gcgattttga cgtaaaataa
      961 ctgagtaata tcttggttaa cgggaatgaa gataactttt acagacaggg aaatgcaaag
     1021 agcatggcgt gaaaattctt ctgcctatca taatcataat ggagtccgaa ctaatgccca
     1081 ccgcttatta ttattttatg ctgttgaatg tggtttaaaa gcagtgttga tgaagaaaaa
     1141 gaaagtaaat cgtactgatt tatatccaga aatattaaaa aaggggcatg atataaatgg
     1201 gttgttagaa tgtttatacc ctggcaataa ttcattgcaa atctggaaac taccaaaaca
     1261 gttatttatt caagatattc aggataattc ttatgttaag ataaaacaag aacgacaatt
     1321 aacgcctgat gacattaacc agatttggcg ctatggaggg aagttcatct taaaaaaaga
     1381 tgagagtgag aataaacggg aaaaaataac agacgaagac atagaaaaaa aattgttaaa
     1441 cattgttgaa ttgattaaaa aagaacttca aggactatga aagattttaa attactgact
     1501 tggcttgata ttagaagaat ttttcgccgc aaaactaact atgggactaa tttaccagag
     1561 aacatagtaa gtattaggtg tttttctgat gctgtagaaa taaatatttc tgatgaaaat
     1621 tgtataaata aagtcaatga cgtattaaaa gaatggtttg aggattcgta tcagcaagaa
     1681 gagtctatga ttcaacttga tgttagtaat gctacattac ccgtagaatt tatctctgaa
     1741 gaagaacctt atataactga tattgaagta cgtccttttt gggaagaaat tgcttatcta
     1801 gaaagtgatt cagaaacaga aaccgccatc aaaaaaatag ttaagctacc agaaccatat
     1861 acggaaaaac ttagtttaat agctttttat tcttttaaag gtggtgtagg cagaacatta
     1921 aatttagcag cccatctttt tgctttgcta gatagagcta aagagttaaa taagtctata
     1981 aaagtcttag taattgatgc ggatttagaa gctcctggtc ttacatactg gaatgaatcg
     2041 tcaaaaagaa aacaaccaga agtttcattt attaattttt tagaaattta tcattattca
     2101 ccaattgata gagaagaagc acttgcttta tttgctaacg aagtaaaaaa atcagtgaaa
     2161 catgaaggaa attcacaagt ttatttttta cccgcatttc taaaagataa tgaattatta
     2221 gatatgccta ttttacctga acatttagtc agaggtatag atggaacatg ggaatacggt
     2281 aatgctattc atcatttagg tgaaatttta ggtgtagatt atgtttttat agatttgaga
     2341 gcaggtttaa gtgaaatatc tagtcctata atttttgatc ccagaatcca gcgtttcctt
     2401 gtgacaacaa ttaatgatca atctattaga ggtacaagtt tagttttaaa acaaattggt
     2461 aaagttgctc catcaaaaga ggaagttaat aaaaaaatat actatgatcc agccatcatt
     2521 attagtatgc taaaaacaga atttaaggaa ttaccaaatt atattaatgc tacaactgac
     2581 ttagagtcta attatgtaca atctaaagag cctacgttaa tagatactag attaaatact
     2641 caagaaactg attttaatga gaaattactg tatatccata actgggaaga tgcccgctca
     2701 aaattaaaag agactacggt aattgaaaaa gctatagatt gggcaagcca acaattaatc
     2761 aacgctgaaa aggaagtaca aactacaaaa gacaaaggag acataaaatc acgacaagaa
     2821 caacaagtta caaggctgag agatttatgt caaaagtatg aacttgctga atcaggagaa
     2881 ggtgaagatt tactaataac agaaccttta caaaatttag caactaattt tcgagatgaa
     2941 ttacctcatg taatatcaat tggagcgaaa ggtgcgggaa aaacttttaa ttatatccaa
     3001 ctttcacgct ttaaatattg gggaaaattt ttgaattcta ttgataagaa tgaaactagc
     3061 tcaattcaaa caaaaaccta tatattgcct ttcctggagt cgagtaacct taaaaataaa
     3121 gcaaaaactg taattagtga agccagaaat gaggttagag cagttctagg tgtgaatgtt
     3181 cctgagtttg tacattcaga gtataccgat aggattaaaa cggcacttac agagcaaaat
     3241 tgggatgaac tacaatggac aaaattttgg gtgaatgaaa ttgccagagc tatagccatt
     3301 aaccaaaatt tagatactcc taatactctt agcagcataa atcaagattt aaaaaataaa
     3361 ggattaaaga ttatcttttt gtttgatggg ttagaagata ttttccctaa gattgcctct
     3421 aatgatcaac agcagaaagc cttaaaaacc ttgattgatg atttgccaaa gaaattgtca
     3481 gaaattaggc aatctcatct tggtataata attttcttgc gtcgtgattt tctaaggtac
     3541 acaattactc aaaatttgag acaatttgaa aatctttacc gttcttatga tttatcttgg
     3601 aatgaagatt cttttttgaa gttagtttat tggatttgta gtgaatctaa tgttataggt
     3661 gcaaaaaaag atagtaaaga tagtatttac agtctcagtc aagagaatct cgtagctgaa
     3721 ttagaaaagc tatggggtaa aagactaggg gcagaaaagt ccaaagaagc ctacacagct
     3781 tcttgggtat ttgcagcttt aacagatttt aagggcagac ttcaggccag agatattgtc
     3841 cgctttttgt actatgcggc gaagatcaca gtagataatg ctaaagaaat acagtttgaa
     3901 aagtggtcta caagtcggct attaccccct caagctattc gccgcgcttt aaaaccatgt
     3961 agtgaagaaa aagtaaaaga agctaaggaa gaatatccaa ctttcaaaac atgggtagaa
     4021 gaaactctac ctcctcagtc tgaacgcaaa ataccctttg ctgtagaaaa attcaatatt
     4081 gatcagcaaa ccatgggaat gttagaagaa atgggtgtaa tttatgaaga tacagctaaa
     4141 gaggacatag ataggtttta tatgcctgaa attttccgcg aagggttagg tttttcaggt
     4201 caaggtgcgc gacctagaat agtagcgttg aagcgtcggg tactagggaa agggattttc
     4261 gcaaatcttc agtgaatagt cgaataaata acaacggaca actgacaact aaactaatca
     4321 ctaatttgca ttttgcttaa aattcgtcgt gagacattaa aaaataccaa acctaaaatt
     4381 gtaaaatttg ccgattttaa aagctgcatt acttgggcaa ttgctacttc tggattgtca
     4441 agaactatat gtaaactatt cgcaaaaata gaaactctcc aagcatcaaa ttgttgtttt
     4501 aatagtttag aagcagcttg attttgatta acaataattt ctatgagttt tcctggttga
     4561 gaatctttaa tataactggg tgaaccttca gccgcgattt ctccagctac cataaaactc
     4621 atccggttac attgttcagc ttcttctaaa taatgggttg tgactaaaat tgctgtacca
     4681 tttcgcgcaa aatcattgat tagtttccaa aactgacgac gtgctaaagg gtctactcca
     4741 gatgttggtt cgtctaaaaa taaaatatct ggttcgtgca taacagaagc accaaaagca
     4801 acccgttgtt tccaacctcc tggtaattgt cccgttagca tattttcttg tccttctaac
     4861 ccacaggtag atatgaccca atcaattttt tcttttctaa gtttgcgggt aacgctgtaa
     4921 acaccgctat aaaattctag attttgcaaa gttgttaaat cgtcataaag ggtaaatttt
     4981 tgactcatat aaccaatgcg ttttcttaat ttggcacttc gcaaatttcc ggtttctcca
     5041 ccgagagaaa tttctcctcc actagctgct aataatccac ataacatttt aattgtggtg
     5101 gtttttcctg cacaatttgc ccctaaaagc ccaaatattt ccccataacg cacttcaata
     5161 ttaacacttt taacagcttg aaatttacca aagacccgat tgagattatt cgcataaata
     5221 gcaatttgtg aagatggtaa ttggtaattg gtaatgggta atagggaaga atttttttct
     5281 ctatgaatat tctcatttat ttcttgactt ttatttccgc cacgagaacg aggaaattgt
     5341 aaaaatggtg gtgcagaacc ttgttgtcgc agacgagtaa caaagacatt ttctaaagtg
     5401 ggttcaccat gttcaatatt gggatcatat tgttttagta attcatttac ttgggtttca
     5461 cctatagtta tatcttccac taaaacatcc aagcgattcc tacggagcgc ttcgctatcg
     5521 ccaaaagttt gcacatcaac tacatttgta tgtaaattct gcaagagaat tttctcgctg
     5581 atttccaaat tagcggtttt tacttccaaa cgatgtaagc ctaaatggtt gcgtaaagcc
     5641 gctggagtgc caatttcatg aattaactgg gcgttgggaa taccaggatt gaagcctgtg
     5701 gtcttggttt gggttaatgc cccttggata gcacttaatt gttctcgtgt ggcatttacc
     5761 gatgcttgac gggcttctag ggtggctatg gctgtatcta atgtagtttg tgattggtca
     5821 aattgctgtt gattaatagc accttctttg ataagctgtc catagcgatc gcggttaatt
     5881 ctcgctaatt ttacttctgc ctctgtttgc ttaacttggg cttgtgtttg taataattga
     5941 gtcttagccg cggctacgtt agattttgcc tgttgaattc gtccttgggt atccccttcc
     6001 gactgctgta aattgagttt tgcttcccta atttgactat taatttgttc aatttcactt
     6061 tgcaccctat ccacatctgc aattgcctgt tgttcatcag attgtgcaga tgttatccta
     6121 gcctcagttc ctcttaattg ttcttgtaat aattgatcat tactgtcatc taatttaatt
     6181 aattcttgtc cctttttaac ataagcccct tctcggaaag caattgactc aattcttccc
     6241 gaacgcttaa tcccaatttc ggtttcataa ccttcaattc tgccacttag tttcagtgta
     6301 tctactgctt tttgtggttg agttcgccac actgcataac taataccacc tcccacaact
     6361 aacaacccca ataacaaagg aattggtttt ttacccttct gctgcttaga tggtgggata
     6421 ggaacattag taaaattgtc tggagatatt ggcgcagttt gagacatata gggctactat
     6481 ttgatttttg aacaagctgt aaaccgtaaa ccccatcgaa tcaacgattg agtctcagta
     6541 taatgaacaa caatcaaacc ggattcctat agtagtttag aacctgttaa atatccgggt
     6601 ggtttaggtt taaaatttaa ttgaccgttg aggaacaaag aacgtaattc tttaaaagat
     6661 ttaaatttat tttatcctat ccccccggat aggatattat gctacaaatt gagagagatc
     6721 atctagtaat tgtctaggct tgtctccctg ttctagttat cttgaggaac tcattgtggt
     6781 tgcaaccccg gaaaaactgc acgctaccca tagccacgag catataccca gtaaagaccg
     6841 tgtagccgtg ttactgatgg gctatggcga agtcgaaagc tacgaagatt ttgctaacta
     6901 taacgaacaa gctttaaatt tactaactgc taaattcgct cctgttccta cttggattta
     6961 tcccccttta gccaaacttt tggcattatt tgatcgtcat gaatggggac acacacatca
     7021 tgattttatc tcccctcata atgccatttt tgaaagacaa agagcgggta ttgaacacga
     7081 gttacaacat aaatggggta atggtgttca agttttcaaa gcttttaact tttgcgctcc
     7141 ttttttacca aatcaagttt tagccgaaat taaagatcaa ggctttagca aactgctgat
     7201 ttatccatta ttggttgttg attccatttt taccagtggt attgctcttg aacaagtaaa
     7261 taatgctctg gtagaattag ctgatggtga tgaacattgg atcaaagccc aaagatatat
     7321 tccttcgttc tacaatgagc caaaatatat tgatttaatg gcgcatttgg tagaagaaaa
     7381 aattcatact gatttggcta cgggttattt accttcgcaa attgggatta tcttgatgaa
     7441 tcatggttgt ccccacaaag cgaaaggttt tacttcggga attgatgaaa gtcaagccat
     7501 gtatgagtta gttagaaaca agttaattaa caattatccg ttaatttctg tgggttggtt
     7561 gaaccatgac acaccgttaa ttgaatggac tcaaccaaat gctacagtag ctgctcaaaa
     7621 tttgattcaa ttgggtgcaa aggcgttgct atttatgccc attggttttg cgacagaaaa
     7681 tcatgaaact ttgttagatg tgcatcacat tattcatgat ttggaaaaac aacatccaga
     7741 tgtagattat ttacagatgg cttgtgttaa tgatgatccc caatttttag ctatggttgc
     7801 tgaatgggca aatgcacata tagcagaatt gatggaaact gaaggtatgg ctgttaattc
     7861 agaatcagct attactcacc accatcacca tcattagaca tctccaaaaa agaatatagg
     7921 gacatatagg gacaattaat gaattgtccc tacaagagtt ttaggctacg catattgagt
     7981 aattgggcgg ttagaaaccg cgtctagaca ggcaaaaccc acactatggc taacgccacg
     8041 ctacgctatc ggcaagctca gtgaccgcct gggcgggtta aaaatattta gtttttctta
     8101 gtccacttag gtgggctttt ttgtcgcagt ttattgctaa agttaaaatt ttttcacccg
     8161 caatataccg tgaacgacaa catgagggaa cttcagttta aaacgagaaa gtagtcctca
     8221 ccgtaccaac aactacatca ggattattat tggtttgatt aggcgcaacc aaccaaatta
     8281 cacctggtgt aattgagata tgatcattta gttgatactt gtagaaagct tctaagtgca
     8341 acggtgtggt gcgattaggg atagtgctga ttacatcact tgcaccacct aaaaatggtc
     8401 tatataaggg aacgacaccg gaacgagtag cataaggggg aacaccgacg acaatacctc
     8461 ccagattacc ttgtttaccc aaatcaggaa aggctagggt gatggcataa ctatacacat
     8521 cagcactttc gttatctgtt cctgcggatt taccttgttg attagtatac ataaaccaac
     8581 tattaacggc aaacttggga gaaactcgcc acaaccccgc tacaccgtaa gcgttaattt
     8641 ctcgtctagc attatcggaa attaaacttg gtgaattggc ggaaattgtt cccacatcat
     8701 tgaggaaggt gggtgttcct gcggtataac cgttgacgta agttaagcca aaagctaaat
     8761 ttttggtggg ttggatactt aattgcgcta aagctgaata ccgaccatca aaaaagcctc
     8821 cagccgttgt cccgttgctg ctatcgggtg ttaaaccttc tggactatta gcatttgggg
     8881 ctaagtatcc taaactcaag ttaatagcgg gattcaattg ataatttaag cccaaacccg
     8941 caccttggga aacaaggcgg taaatggggc tatattgagc aaaggtagaa agtgaaccag
     9001 aacctccatc ttcatcacca actgtactga atacattcgg taaatagtct acgtgttctc
     9061 ctcgattggc aaacacagcc gcgcgtattt ttttacctat gggaaactta taactaacag
     9121 ttcctaattc tacactaccg gctgtatcag ggaactcttg gttaaaggtt tgtccgcctt
     9181 ctggtgtggt ttgtctactt cctaaggaag ctaagaaggg atctgcacca tagcgaaacc
     9241 cgccagccct ttggggatgt ggagtgctac cagcttggag tctaattttt agctcatctt
     9301 gacctgtaaa actactgact aagttgaggc ggactctgtt agccaaaata gtgctattgc
     9361 gggggacacc aacgttgaaa ggatcactat ctccagttaa gacatcagta atggcaaaaa
     9421 tcgcttcacc ggaaagtttg gtagttgtgg aaaattgctg actttctaaa gttgcggtgc
     9481 ggctttctac tgcatctacc cgccctcgta aagttgctaa ttctgaggta aattcctctt
     9541 gtagccgttg aatagtcgct aaatcttctt tttgaactgc atcagcagta gctgtggcta
     9601 ttagctcatt aactctatct agacaagcat ttaaaccagc ggaaaactca taacgagtca
     9661 tggcacgatt tccccggaat gttccattgg gataacctgc tacacaacca tatcgttcta
     9721 ctaaagattg taaagcacta aaagcccaat ctgtaggttg gacatcagac aactgagaga
     9781 cggaggttac ttgtgctaaa tcatcgtttt ctgctatttc actagcccat gctaccggcg
     9841 aaatcaaaac tactggggtt gctaagacta aacctaagaa aatttttaac atcacatcct
     9901 cactgataca ccctcatctg atctacttta cacaaatact cagataatga taattattat
     9961 catagttaag tatttgtgta aacacttatc gagtcacgtg atgaaaaaag tcaactgtca
    10021 agattctgct tggtttcggg ctatgtcatt gaaggaaagg attgtagcca attcggaaga
    10081 gttaggatat gattctgagt tgggatataa acgatttcaa cgctggaaat cggcatcaag
    10141 ctttgctaat tcgagtttat ttgctcagaa gttggtaact gagggaataa cagaagagga
    10201 gttttgtcgt attttgggac aatctgtagc accgatacct ttatcatggg tggaagaaat
    10261 tcagcaaatt tatgaatatt taggcgaaaa agatattaca actgtgctgt ctaattctag
    10321 tttatgcaca catcctaatt ttgggttttt gaaggcgatc gcacctttcc ttgttcaagg
    10381 tatgattaaa ttagaaattg gattaaataa tatacaaaat attcctgaaa ctttaagtga
    10441 tattcatgat gttttattag agggattacc agaaaagctg ctattaatgc tgaatgcaac
    10501 cttagtatta gaagtgaata tagctagatt acaaggttta ttaacaggtg ataatgccca
    10561 agaaagattt tatagcttta tacaacggtt acgaaatccc gaagtacaat tagcattgtg
    10621 gcaagaatac ccagttttag ctagacaagt cctagaagaa attaatcgct gggtagaaaa
    10681 tagcatagaa ttgattcaac atctttctca tgattgggta gatatttgtt accaatttca
    10741 gtcaccaacc aagctaggaa aattaatcaa agtcaatcgg ggaaaaggtg atagccataa
    10801 taatggtaag tcagttacta tactaacatt tgcaagtggt tggcagctag tttataaacc
    10861 gagatcatta gccatagatg ggcattttca acaactgcta tcatggttaa atgcaaaagg
    10921 ctttaaacca gcttttcaga ctttacaaat tctcaaccga gataattatg gttgggtaga
    10981 atttgtgagc tttcaagaat gtgattcagc agaggaagta gaaagatttt atcaacgtca
    11041 aggtggctat ttagcattat tatatgcttt ggaagctacg gactttcact ttgaaaactt
    11101 gattgcagcg ggagaacatc ccattttaat tgatttagaa tctttatttc atccccgtag
    11161 taattataaa ggtacagcag cagatactct agatcgagag atagttgcag attcagtatt
    11221 gcaagttggt ttactaccac agccagtctg gggaaatact gaagcagcgg gaatagatat
    11281 gagtggtttg ggaggtgctg ggggacagtt aacaccagaa aaagtcccaa aactggtgca
    11341 ggtcgggaca gatatcatgc gggttgaacg tcaacaggct gttatcgcag gtagtcaaaa
    11401 tcgccctcaa ctaaatcaac aggaaattaa tgtacaagaa tatacagccg ctattacaga
    11461 agggtttact gctgtttacc gaattttatt acaacatcgc caggaattac tcaatatttt
    11521 agcccggttt gcagaagata aagtgcgtgt ggtaatgcgt gctagtagag tctatgcttt
    11581 attgctgagg gaaagttatc acccagattt tttacgagat gccttagagc gcgatcgctt
    11641 atttgataaa ctgtggatag atgtagaaaa ccgtccgcaa ctgagtcaaa taatttccgc
    11701 agaaattaac gcattgtgga aaagcgacat tcccttattt accacatatc ctcattcccg
    11761 cgatttatac catcaagaaa caggcttaca catttctaac tttttcaacc aatcaggaat
    11821 agaattagta catcatcgcc tgaataattt cagcgaaaaa gacttacaac gacaaacatg
    11881 gtttattaaa gcagctttag ctactttaga aatgagtaaa actgcggata accatcaaat
    11941 tagattaggc aaaaaagcct gtaatataag cactataatc ccaacaacga aagaccaatt
    12001 cttagaaata gcctgtaaaa ttggcgaccg tttagaactc ctcgcacaca acaacggtaa
    12061 atttgttaat tggatgggtt taagcgttac tcccaatcag caatggacat tagcaccctt
    12121 gggaacagac ttatatgcag gtatacccgg tgtagcttta tttctagcat atttgggaga
    12181 aattacccaa aatcatcttt atacaaacct agcccaagca gccataaaaa ccctaaaaca
    12241 gcaactcaaa agagactcaa ttaaattcat aggtggcttt agtggctggg gaggaataat
    12301 ttacacatat acccatttag gaatattatg gcaaagaaaa gacttaatag cagatgcagt
    12361 tgccttagta gcaaaaattc cccccttaat ttcccaagat aaacaactag atataattac
    12421 tggtgcggct ggttgcattg gtagcttact cagtttatac caaatcgttc cagagcagtt
    12481 cattcttgat gtcgccagac aatgtggtga acacctcctt acccaagccc aaattacaga
    12541 tactggtatt ggttggatat ctccagcagg gggaaatcaa cccctaaccg gatttgcaca
    12601 tggtagtgct ggctttgctt gggcgctggg aaaactagcc gtaacgactg gaaaccaaga
    12661 atttcaaacc gcagccacag cagcaattaa ctacgaacgc agtcattttg accctacaac
    12721 caataactgg atagatttac ggataaaaga ggaaaaaaat agtttcatga cagcatggtg
    12781 tagtggtgcg ccgggaattg gcttaggacg tttaagtatg acagagaata cacccgactt
    12841 aatcatgtat aaagaaatta caactgccat ccaaactacc ataaaacaag gatttggtga
    12901 caaccattgt ctctgtcacg gagacttagg aaatattgac ttattattaa tagccaatag
    12961 catattaaat gatccagaaa ttttccaaca aaccgaaaaa attgcctctc aaatattaga
    13021 cgatatccaa gaaaataact ttctttgtgg tgtcccatta ggactagaaa ccccaggatt
    13081 aatgacaggt ttagctggta ttggttacgg acttttacgc cttgcttacc cccaaattat
    13141 cccttccatt ctcctgcttg aaccgcccaa acaatcatct taatctttac acctttttgc
    13201 ctttgtgtga tcaaaatgaa atatccaata attttacaac ataacgaaga agattgcgga
    13261 ccagcttgtt tagcaacaat ctctaaatat tacggacaac tatttacaat tacccgtgtt
    13321 cgtgaagcct ctggaacagg acaattagga acaacattac tcaatcttaa acaaggagcg
    13381 caggtattag gatttaatgc acgtggtgtg aaagctgcat tagaattagt agataaaaaa
    13441 caaattcctc tacctgcaat tattcattgg aaagggaatc attggactgt tttatatggg
    13501 cgaaaaaatc aaaaatatat cattgctgat cctttagttg gtgtgcgaac tttaacaaaa
    13561 gaagctctgc taaagggctg gacgaatagt gtaatgctac tattagaacc ccgtgtagat
    13621 tttctagaac aaccagatga tcggggaaaa ataggaggtt ttaaagcact gatacagcgg
    13681 tttttaaact atcgcttgat ccttgcagaa gctttattat taaattttgt cgtcgggtta
    13741 ctttccctgt tgtcaccgtt tttgattcaa attctcactg atgatgtttt agtacgtgga
    13801 gatacccaat tactcacagg tattgcactg ggaatattaa caatgagttt tattagtagc
    13861 tgtttacaat gggttcaagg taatttagta tcccattttg ctcatcgttt ggaattagat
    13921 ttagtatggg aatttgctag aaatatttta cgtttaccat tgtcttatta tgaatctcgt
    13981 cgcagtggtg aagtggtaag tagattacga gatattcaaa ctattaatca attggtttct
    14041 caagttgggg taattttacc aagtcaatta ttaattgcaa ttacctcctt aattttgatg
    14101 ttattctaca gttctcaact gacattagtt tcaatatttg tagctatgat tatgactttt
    14161 tctactgtcc tttctttccc tagcttacaa caaaaaatcc gcaccgttct gggtttagct
    14221 tctgaaaatc aaggtgtatt agtagagact tttaaaggtg cattagttgt gaaaactacc
    14281 aatgctgcac cagaattttg gcaagaattt caaactcgct acggaagaca gtcaaattta
    14341 atgtttctca ctgtccaaat cgttttaata aataccatct tttctaattg gatttctact
    14401 gctggtggga ttattctcct atggtatggg agtattttag ttattaatcg agaactttct
    14461 attggtcaat tattagcttt taatagttta aataccaata ttcttggatt agtaaatacc
    14521 tgcgttcgct tcattactga ttttgctcgc gctcaagctg caactgaaag attaaatgag
    14581 gtaattaatt cgactcctga attttctgaa gttagtcaaa agccttttgt aaatattccc
    14641 gacaacgcgg atcttatttg taaagatatc aattttcatc atgcgggtag agttgattta
    14701 ttaaaggatt tttctctaac tttaccgggt ggaaaagtga ttgcaattat cggtaaatct
    14761 ggatgtggta aaagcacctt agctaaatta attgctagtt tatataattc ccaatctggt
    14821 aatattcgca ttcatcacta taacctttct gatattaatc ctagttgctt acgtcaacaa
    14881 atagtattaa ttcctcaaga tgcacatttt tggagtcgtt ctattttaga taacttatct
    14941 cttggttgtc ctcaagttaa ttttgagcaa atagtcacag cttgtcaagt tgcagatgca
    15001 gataatttta ttagtaaatt acctgaaaaa tatcaaacta ttttaggtga atttggagcg
    15061 aatctttccg gtggacaaaa acaaagatta gccatagcta gaggtattgt cactaatcct
    15121 cctatcttga ttttagatga atctacagca ggtttagatc ccattagtga aagtttagtt
    15181 ttagatcgat tactcgctta tcgtcaaggg aaaactacta ttttaattag tcatcgtcca
    15241 agagtgatta aacgcgcaga ttggattgtc ctgttagaag ctggacaatt aaaactacaa
    15301 ggtactccta cggaactact tagcatagca ggtgagcatt tagatttttt gattccttga
    15361 attgtaatta agcatattta ctctacacgg ataaattact tgacattttt tatgagaatg
    15421 attattattc taatattggt gaaaatgtca tcaataatac ttttacaact gcgacttcta
    15481 gggaatattt cgttatttcc tagttgaaac gtagagtttt ttaatgaggt taaatatgtc
    15541 taatctagat atcattcgcg cttggaaaga cgaagaatac cgcaacagct tgagcgcaga
    15601 acaacaggaa caactaccag caaaccccgc tggtttagtt gaactgaatg atgaagatat
    15661 gtcttctgtt tctggtggtt gtacaacctg tggtaatcct ttacatacat tattctggac
    15721 ttgtaaagct gtatctagtc cttttgatac catagcttaa tttcatttaa taacatttca
    15781 aaaattcaga ttcctgactt ctttaagaaa tcgggaatct ggatattatc gtcatcatga
    15841 ataacacaat tcccaatttt ttaccaactg caaaatctga tgaatactta cctagcattg
    15901 gtatttggac aagattagga ggattatttt tagttggtgt ttttggtgct tctgtcacta
    15961 tttccacgtt cacaaaatat cagcaaactg ttaaagcatc tgctattgtt cgtccaactg
    16021 gtgaagtgcg aatagtgcaa actgctatag aaggaactgt taaaaaaatc tccgttaaag
    16081 aaaatcaatt agtaaaaaaa ggtgatgttt taatcattct tgatgatatc caattacaaa
    16141 atcagaaaaa tcaactcacg gtaaatattc agcaatctca attacaaatc aggcaattga
    16201 atgctcaaat tgcagcttta aatcgccaaa ttgctacaga gacagaaagg aataaacgca
    16261 tagttgcatc tgctatttct gaagttcagc ggacaaaacg ggactatcaa gatagaaaag
    16321 tagctgttag tagtgaatgg caagaagcgc aagctaatat aaagattgca gaaaatgaat
    16381 tattacaagt aaaatcagaa ttgcagtcaa ttcaggctaa tttagaaagt gcagaagcag
    16441 gattgaaagc cgcaatagtc aagcggttgc gttatgaaga tatagctaaa tctggttcaa
    16501 tttctcaaaa tcaattagag gaagttcaac tagccgcaac tcaacaagcg caaattgttg
    16561 aatcacaaaa agccacatta gcaagtcaaa aacaagttat tcaacaaaaa caacaagttt
    16621 tgacatctgc aattgctaga agtaaaaaag cagcttcatc tctaaatcct agtaatgcag
    16681 taatctttat tagtgaagaa aaagttgcta ctgaacgcgc aaatggcaaa actaatttag
    16741 cgagattaca acaagaaaaa gaaagtttaa tccaaggtaa aattgaaatt caaaaccaaa
    16801 taaataatac agaaaaagaa ctccaacaac ttttaactca gatacaaaaa actgttattc
    16861 gagcttctgc aactggaact attttaaaat tagaattgcg aaattctgga caagtggtaa
    16921 atttgggaag tgctattgct caaatttctc ccagttatac ccctttagta attaaagctc
    16981 gtgttgctgc tgctgatatt agtaaagtct ttgtttgcaa ttctccagaa gtagtaagtt
    17041 gtcgaaaagg aaaggtaaaa atgcgatttt catcctatcc ttacccggat tatggtatct
    17101 taataggtgc ggtgaggtca attacagcag atgcaatttt accccaagat aatatcacag
    17161 cagagggtta ttatgaagtg acgattgaac cagaaaactt gtatttgcaa agagatttac
    17221 aacaatatcc tattcaagct ggaatggaag ttgtcgcgga tattatttct gaggaagaga
    17281 gtgtattaac atttattttg agaaaaacta ggctgttgac aaacttataa atatttcatt
    17341 atttgtttaa ggaaatatac taaacatggt taagacatag actcttgcaa gattacgaaa
    17401 aacccagatg tttaggggtt tcaaaatagt ctaaatatta ggtggcgatc gcaaaatgct
    17461 gctgcaagca gatcgctaat cttgtagttg aggaacgaaa cccaacatca aaaatatcga
    17521 actcaggtga tatcaattcc ctaccaatgg tgcattcaaa gtcttctcaa tgcgatcgcg
    17581 tgtttctaat aagaaagctt gagtatattc atcttcagaa tttacccgtc ttaattgatt
    17641 atttaattgc ttgagtttat accaagccaa agtacgggca tcttcaggag tagcttcttt
    17701 tcgcaacacc attcccatca gtacatttag gtattcccgt tgtaaacctc ttcgcagact
    17761 ggaaatttgc aatttacctt taggttgcaa aacctccgac caaatcccag attgtaaagt
    17821 atcaaataac tcaggcaatg tgagagattt tcctgatgca ctttttaatt ctagatcctt
    17881 aatccgagtt aggcgatcgc ttgccaataa atcccgcaac accgccgtct gcaccaacaa
    17941 cactaaatca tgaatcggat aatctaaccg tccgacttga atattagtcc cccaatgtag
    18001 ccaccgcgaa ggtactaatt tattcagtaa ttccggggga aatttcaaag catcttccgc
    18061 aaaaacatac ttttgcattg tcatcaatgc ttgtcgctgt tgttctaccg gtacagggac
    18121 aaatggtaat tgtcctttag tatcatttgg tttaactcga taaaaagact gaccaccaat
    18181 gtatttactg gtatagtata aattctgtaa ataatttctg aggatggtgt taaaacgctc
    18241 ttctacatcg ctagaattct ctgcatctat agcatatccc tgatttaatc gttcccacat
    18301 ccgccgcgca ttagccaatt gtgaatgaga ataaaccaat acattactgc tatgatccca
    18361 aggattcacc gtcggatcac tattagataa atcctcatca ggagcataac tcaactctcg
    18421 ttggttagat tttccagcaa ttgctgctaa aaacgacttt tctcccatgg tagttgacgc
    18481 ttgactggga gtgtaaccat actcaattac ccattcatca tagggtccca cctgctgtgg
    18541 aaaataatct ccctgcttga caccattagg ggcaatgttt gggggaatat aatccataac
    18601 cgatgctgtc atccctttag tctgcgtaat ttctggatta ttcatctcct ctggagatag
    18661 taaggtacta ccacggaaat tatgacgcaa acctaaagta tgaccaactt catgggtaat
    18721 aattaaacgt aaatattgat ggatataatc ttttaactgc tctggacttg gtgtagtgtt
    18781 tcctaacatt gacattgcta aagaaccaaa agccaactga ttagatgctt ccatgccata
    18841 acataaatca taatctgtcg ctagtttaga caaattgcct aatgattttg gagatttttg
    18901 attacctttg ccacacaaac gcccattgtt gaccaatgtt gataaagaag tgctagtttg
    18961 tgaattttga ggttgaataa tttgccgata atcatttttt aataatcgga caaaactacc
    19021 atcaatcaga atatctgcat tcaaaatttc tccagttaag ggattaacac gggatggacc
    19081 catcgcaaaa aaaccatcta cagtattaat ccaacggata gtattatagc gaatatcggc
    19141 tgggtcccag gtagcattat caggcatttg ttgaacttga atagcatcct tgaatcctgc
    19201 tttcaaaaag gcttgattcc acatcaaaat tccctctttg atagactgac gatattctag
    19261 aggtacagca ttatcaatcc aaaaaacaat cggttttttc ggtggagaaa ttgcggctgt
    19321 gggatcttgt ttttctaaat tccagcgatt aatataacga acaaaagtat ctctccgttc
    19381 atctttagat aaatcttgat aagctgtgag gaaataacct acccgttcat cagctaaccg
    19441 aggttgatat ttagtttttg gtaattccga taaactataa tgtaccttta aggtaaaacc
    19501 gcgactatct ggtaaaacat ccgaattctt gccaccatta gcaaaattga aaatagactc
    19561 aatttctaaa ttattgggaa atactttcgc attaccaaga taaccttgat cgggactaac
    19621 agctaattct aaattagtag ataatcctgc caaatctgtg agtagtaaat cacctaaatc
    19681 aataagaata gtttttcctt gtgaattaat actcttaata ggaatagtgt aaagaacaga
    19741 atcactaaat gatctcgcta ctgatctagc ttggggatct ccttcacgag tccgaaaatt
    19801 gacattacga accacaaact gaatttgatt atctaccttt tgaaagtaga ataagaagtc
    19861 ttgtaatggc attccactat aaataccctt ttcaccaatt cccgattcta aagttgagtt
    19921 tgctataaag tttttttgga gttgttctgg tttaatttcc agatagattt tatttttatg
    19981 tttatgacga taaatagtaa agattccctc tgatttttgg gtatccttgg taacttctgt
    20041 aaaatcttct aattcatctt ctttcggtga tttagattca ggtttagctt tcggtttctc
    20101 tatttctttc ttaacctgga gaaatggttg tttgccaact tgctttagat ctttaaatac
    20161 ccaaacaaaa ttttgtattt ttacctgatt attttgatca ataactgcta ttttggaaga
    20221 tggtagtttt aattgttgaa caatcttatc cacattagtg gtttgtctct ctatttctat
    20281 atctgaatta cggggattat ttattaatga ttgagcatta gcagtttcta tggaaacaaa
    20341 tagactatta aacaaaatga gagcgaaagt aaacttattc atttcctaac ttcctgataa
    20401 ttattgttta atagccgtct gaaatggaaa ctctccaact ttgcgccttt gctcctttgc
    20461 aactgggcgc gaaacataac ctatcctaat tcgtaactga ttgggcttcc tgatacataa
    20521 tttcctggaa gtgaatcata tctttttggg gatcagccaa actaactttc actaataaat
    20581 tttctcccaa actgacagaa cgcctgaagg acataggcaa ttgtaaaccc aaatcttcta
    20641 ataaaattag tcctaaattg ctatcttctc gtaaccacat taataccgtt acctgccaaa
    20701 cttgttcagg atgacgacgt aaatattcta aagcgtaata tctattagtt tgtcgttcca
    20761 ccattgttgc ttcttgagtg atgctgctga ccgtcatcat cacttctttg agttgttcag
    20821 cagagaaggg taaaccttcg ccgcgtaaat gcgcttttaa ttggaagtgg gtgagtaagt
    20881 cgctataacg acgaatgggg gaagtagctt gagtgtaggt atctaaaccc aaaccagcat
    20941 ggcgcactgg tgtaatgctc atttcgcttt taggcataca gcgtcgcatc gcacaggaac
    21001 gaacaaaacc ggctggaagc aggagcagtt cttcctctgg aggtaattct ggttggggtt
    21061 ggccgcgaaa gggcagcggg atattatgag tttgtccgta acgggcggca acttctccgg
    21121 caagaatcat catttctgcg actaattggc gggaggaaga atcatctaaa acatcaatat
    21181 tgatatcatc gtctttgact ttgatcatcg cttcgggcat attgatactg atagcacctt
    21241 gactataacg ccaagttttg cggatttttg cccaattagc gatcgcctca atttctggtt
    21301 ctgcttgaac tcccaactcc agcatctcat ccacatcttg ataggtgagg cggtaggtag
    21361 gcttaattaa accagtgtgt atacagtaat cttccacagc cccaactgca tctaaaatca
    21421 ccccaaagct gagggcgcaa cagactttcc cctgaattaa actcatggga cctgtggcca
    21481 acacctctgg gaacatggga atcatccccg tgggtaaata taccgtacta ccccgttttc
    21541 tggcttctaa atctaattca tcatctggca ttaataaccg cgtcgggtca gcaatatgca
    21601 cccataaccg ttccttacca tctgctaata tctcccaact caaaccatcg tctatttctg
    21661 tagtgctttc atcatcaatg gtatatacct tgagatgtgt gagatcgaga cggtttgtat
    21721 ctaaatctgt aggaggaaaa tcccaacatt cttgcgccac ttctaatacc tgatgaggaa
    21781 attgaacgga aattgatgaa cggcgcagga acaggttttc gtgggaagtc cacaaaccca
    21841 aatctatcaa gagttgaaag gccgcctggg gcgtagcaga acgtcccagc atattcatag
    21901 tttctaatac tgaggctgga ggcggacaag cacgagccaa agaatcatag ttcactttca
    21961 gcatcaccac atccgccagc aaagtcgcat atttttctaa tgcgtctaaa cgctggcgat
    22021 ccagtctttg ccattctacc acttgtccct ggagcgcctg ttctatccgg gctaaaaatt
    22081 cctgctgtcc cttggctttt tgtgattcta cttgaatctg gtgcttgcgt tctgctattt
    22141 gcgctgcgct gcggggttcg taagcgtctc ctttttgttt gaaatagagt ttatcttctg
    22201 ataacaaaca atgggctgca taacactggg gagatgtgga ttccgaaaat agcagatttg
    22261 ccaattggct aggagtgaca gtttctccat cttcaatcag tagttcccaa gctatttcca
    22321 gacttgatgg atctagataa ggctgaactt gacttaaaaa ctcagcgatt tcccctggtt
    22381 tataggtttg tccgttaacc gtgtaggtaa attggttatt tttgatgtta tgggattgac
    22441 cacgttcatc tactacaaac caactagttt taccgtctgg acgatctatc actccaagac
    22501 ggcgatcgcc tttaacccta aattcaacta acgtcccctt atccacaact gtcgcacttt
    22561 aattttaata ttttgagatt tttagactgg aaattctgga ttaaataacg ggtatttaat
    22621 cctttattta ataatttgct gtgagaaatg ctattccagt ttagaattcc atcctcaaat
    22681 ttagcgatat cgtaccattt ttgagaatga attaattaaa tgtttttggc aatttcctaa
    22741 cattaaatat taaattttag attttggact caaagtaact gggcatatcc atgcaactgc
    22801 tacttttttg gatgatcatc caaaatccaa aatccaaaat attcttaacc ttcggcgtta
    22861 atgaagggca ataaagccac aattcgagag cgtttaatgg ctagagtcag agcgcgttgt
    22921 tgctgacagg ttaaaccggt gattctccga ggtaatattt taccacgttc ggtgagaaac
    22981 ttccgcaaca aatctacatc tttgtaatca atgggatctc cgggcttaat tggagaaagg
    23041 cgacgacgat agtaactcat tcttacttaa tctccttgtg aactgtgtgt ttgttgcagt
    23101 gggtacagaa ctttttcagt tctaagcggt tggttgtgtt ccgacggttc ttggtactgg
    23161 tataacggga tacgccaggt gaa
//
