LOCUS       NZ_CP051206            20939 bp    DNA     circular CON 09-DEC-2024
DEFINITION  Dolichospermum flos-aquae CCAP 1403/13F chromosome, complete genome.
ACCESSION   NZ_CP051206
VERSION     NZ_CP051206.1
KEYWORDS    RefSeq.
SOURCE      Dolichospermum flos-aquae CCAP 1403/13F
  ORGANISM  Dolichospermum flos-aquae CCAP 1403/13F
            Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Nostocales;
            Aphanizomenonaceae; Dolichospermum.
REFERENCE   1  (bases 1 to 5151752)
  AUTHORS   Wu,V.
  TITLE     Genome-Wide Identification of 5-Methylcytosine Sites in Bacterial
            Genomes By High-Throughput Sequencing of MspJI Restriction Fragments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5151752)
  AUTHORS   Fomenkov,A., Anton,B.P. and Roberts,R.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2020) Genome Biology, NEB, 240 County Rd, Ipswich,
            MA 01938, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 04-DEC-2016
            Assembly Method                   :: HGAP v. 2.3.0
            Assembly Name                     :: Afl_HGAP3_4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 114.08x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012516395.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 17:24:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,987
            CDSs (total)                      :: 4,921
            Genes (coding)                    :: 4,734
            CDSs (with protein)               :: 4,734
            Genes (RNA)                       :: 66
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 187
            CDSs (without protein)            :: 187
            Pseudo Genes (ambiguous residues) :: 0 of 187
            Pseudo Genes (frameshifted)       :: 35 of 187
            Pseudo Genes (incomplete)         :: 162 of 187
            Pseudo Genes (internal stop)      :: 14 of 187
            Pseudo Genes (multiple problems)  :: 21 of 187
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:01:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1258194
            Orig. end                         :: 1279133
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP051206.1.
            Bacteria and source DNA available from CCAP 1403/13F.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20939
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20939
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20939
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10939](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10939
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            249..404
                     /locus_tag="HGD76_RS06285"
                     /old_locus_tag="HGD76_06285"
     CDS             249..404
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGD76_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGD76_06285"
                     /product="hypothetical protein"
                     /protein_id="WP_168695275.1"
                     /transl_table=11
                     /translation="MSVGAKHLEDKLSVIAKNSSPNASPVQLSVEKICSLFPAPRSLFP
                     VPSLKE"
     gene            complement(393..1100)
                     /gene="folE"
                     /locus_tag="HGD76_RS06290"
                     /old_locus_tag="HGD76_06290"
     CDS             complement(393..1100)
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GTP_cyclohydroI"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012408396.1"
                     /locus_tag="HGD76_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06290"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_015079151.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 8.3e-81,
                     bitscore: 267.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAGSNGSNTSQSPLIPDLAEAINVRPDRNTHNGKEPQIHPPSE
                     EIMDEMMAAVRTMIVGVGEDPEREGLLKTPKRVAKAMKFLTSGYNQSLEDLINGAIFDE
                     GHDEMVLVRDINFFSLCEHHMLPFMGRAHVAYIPNQKVVGLSKLARIVEMYSRRLQVQE
                     RLTRQIAEALQTVLEPKGVAVVMEASHMCMVMRGVQKPGSWTVTSSMVGVFQEEQKTRE
                     EFFSLIRHQPSFF"
     gene            1196..1339
                     /locus_tag="HGD76_RS06295"
                     /old_locus_tag="HGD76_06295"
     CDS             1196..1339
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGD76_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGD76_06295"
                     /product="hypothetical protein"
                     /protein_id="WP_168694533.1"
                     /transl_table=11
                     /translation="MLRPYSCQLSVGAKHLEDKLSVIAKNSSPNASPVQLSVVSRGEAF
                     GR"
     gene            1372..1515
                     /locus_tag="HGD76_RS06300"
                     /old_locus_tag="HGD76_06300"
     CDS             1372..1515
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGD76_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGD76_06300"
                     /product="hypothetical protein"
                     /protein_id="WP_168694533.1"
                     /transl_table=11
                     /translation="MLRPYSCQLSVGAKHLEDKLSVIAKNSSPNASPVQLSVVSRGEAF
                     GR"
     gene            1548..1691
                     /locus_tag="HGD76_RS25180"
     CDS             1548..1691
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGD76_RS25180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_168695276.1"
                     /transl_table=11
                     /translation="MLRPYSCQLSVGAKHLEDKLSVIAKNSSPNASPVQLSVVSRSEAF
                     GR"
     gene            1636..1785
                     /locus_tag="HGD76_RS06310"
                     /old_locus_tag="HGD76_06310"
     CDS             1636..1785
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGD76_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGD76_06310"
                     /product="hypothetical protein"
                     /protein_id="WP_233467078.1"
                     /transl_table=11
                     /translation="MLRPYSCQLSVGAKHLEDKLSVIAKNSSPNASPVQLSVVIKEIND
                     KITN"
     gene            complement(1782..2507)
                     /locus_tag="HGD76_RS06315"
                     /old_locus_tag="HGD76_06315"
     CDS             complement(1782..2507)
                     /NRPS_PKS="Domain: PKS_KR (9-161). E-value: 1.3e-12. Score:
                     39.9. Matches aSDomain:
                     nrpspksdomains_HGD76_RS06315_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079152.1"
                     /locus_tag="HGD76_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06315"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_015079152.1"
                     /sec_met_domain="adh_short (E-value: 1.5e-35, bitscore:
                     121.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFEQKRRALITGASSGIGKATALAFAKAGIDVALVSRSQDKLES
                     VAKAAQELGVEAKAFCVDLAEVTQVKSKIQGIADEFGNINILINNAGIGYTGNLSETPL
                     EDWQQVINLNLTSVFQCMMGILPGMRQQGQGTIINIASIAGKQAFPGWGAYCVSKAGLL
                     FLSQTLAQEERANGIRVIAICPGSVNTEIWDTPTVQANFDRSQMLTPEIVATTILHTVL
                     LPQEAVIQELTIMSNAGVL"
     aSDomain        complement(2025..2480)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HGD76_RS06315_PKS_KR.1"
                     /evalue="1.30E-12"
                     /label="HGD76_RS06315_PKS_KR.1"
                     /locus_tag="HGD76_RS06315"
                     /protein_end="161"
                     /protein_start="9"
                     /score="39.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="LITGASSGIGKATALAFAKAGIDVALVSRSQDKLESVAKAAQELG
                     VEAKAFCVDLAEVTQVKSKIQGIADEFGNINILINNAGIGYTGNLSETPLEDWQQVINL
                     NLTSVFQCMMGILPGMRQQGQGTIINIASIAGKQAFPGWGAYCVSKAG"
     CDS_motif       complement(2391..2480)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HGD76_RS06315_0001"
                     /evalue="4.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="HGD76_RS06315"
                     /protein_end="39"
                     /protein_start="9"
                     /score="12.9"
                     /tool="antismash"
                     /translation="LITGASSGIGKATALAFAKAGIDVALVSRS"
     gene            complement(2666..3646)
                     /locus_tag="HGD76_RS06320"
                     /old_locus_tag="HGD76_06320"
     CDS             complement(2666..3646)
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015140477.1"
                     /locus_tag="HGD76_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06320"
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="WP_015079153.1"
                     /transl_table=11
                     /translation="MATTERKPLLLDFEKPLAELATRIDQIRQLAEENGVDVSGQIRQL
                     ETRATQLREEIFSSLTPSQRLQVARHPRRPSTLDYIQSISDEWMELHGDRCGGDDPALV
                     GGVGRIAGQPVMMLGHQKGRDTKDNVARNFGMAAPGGYRKALRLMEHANKFSMPILTFI
                     DTPGAWAGIEAEHQGQGEAIAYNLREMFSFDVPIICTVIGEGGSGGALGIGVGDRLLMF
                     EHSVYTVATPEACAAILWKDASKSHLAAVALKIISHDLKNLGIIDQILPEPLGGAHSDP
                     LTAATNLKQALLENLDELNRLTPAERRQLRYDKFRNIGVFTELAH"
     gene            complement(3756..4775)
                     /locus_tag="HGD76_RS06325"
                     /old_locus_tag="HGD76_06325"
     CDS             complement(3756..4775)
                     /EC_number="1.2.1.80"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0043447 - alkane biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009457421.1"
                     /locus_tag="HGD76_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06325"
                     /product="long-chain acyl-[acyl-carrier-protein] reductase"
                     /protein_id="WP_168695277.1"
                     /transl_table=11
                     /translation="MFGLIGHLTSLEHAQSVAQELGYPEYADQGLDFWCSAPPQIVDHI
                     TVTSITGQKIEGKYVESCFLPEMLANRRIKAATRKILNAMAHAQKHGIDITALGGFSSI
                     IFENFNLEQFKQVRNINLDFERFTTGNTHTAYIICRQVEEASKQLGIELSKATVAVCGA
                     TGDIGSAVTRWLDKKTDVQELLLIARNQERLQELQAELGRGKIMGLQEALPQADIVVWV
                     ASMPKGVEIDPRTLKQPCLLIDGGYPKNLGTKIQHPGVYVLNGGIVEHSLDIDWKIMKI
                     VNMDVPGRQLFACFAESMLLEFEKLYTNFSWGRNQITVDKMEQIGRVSIKHGFRPLLV"
     gene            4925..5065
                     /locus_tag="HGD76_RS06330"
                     /old_locus_tag="HGD76_06330"
     CDS             4925..5065
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HGD76_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HGD76_06330"
                     /product="hypothetical protein"
                     /protein_id="WP_168694534.1"
                     /transl_table=11
                     /translation="MTVDYRTITPLPPLLPLPPLLPLPPLLPLPPLLPWGNKVVTPVGS
                     Y"
     gene            complement(5062..5760)
                     /locus_tag="HGD76_RS06335"
                     /old_locus_tag="HGD76_06335"
     CDS             complement(5062..5760)
                     /EC_number="4.1.99.5"
                     /GO_process="GO:0043447 - alkane biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079155.1"
                     /locus_tag="HGD76_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06335"
                     /product="aldehyde oxygenase (deformylating)"
                     /protein_id="WP_148766927.1"
                     /transl_table=11
                     /translation="MQQLVDQIEKIDFQSEIYKDAYSRINAIVIEGEQEAHENYITLAK
                     LLPAQEEELIRLSKMESRHKKGFEACGRNLKVTPDLVFAKKFFLGLHDNFQTAAEEGKV
                     VTCLLIQSLIIECFAIAAYNIYIPVADDFARKITEGVVKEEYSHLNFGEVWLQENFTES
                     QAELEAANRQNLPIVWKMLNEVADDAKVLAMEKDALVEDFMIQYGEALSNIGFTTRDIM
                     RLSAYGLATV"
     gene            6402..6737
                     /locus_tag="HGD76_RS06340"
                     /old_locus_tag="HGD76_06340"
     CDS             6402..6737
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016877667.1"
                     /locus_tag="HGD76_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06340"
                     /product="XisI protein"
                     /protein_id="WP_053537543.1"
                     /transl_table=11
                     /translation="MANIEHYRQCIQTILKEHGKFKPKYDEIDNELIFDTTHDHYQLMR
                     VGWDDLRRVYHSVIHFDIKDNKIWIQQNMTESDLAQELVNMGIQKEDIVFGLQPPYKRP
                     YTGYGVA"
     gene            6872..7132
                     /locus_tag="HGD76_RS06345"
                     /old_locus_tag="HGD76_06345"
     CDS             6872..7132
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079160.1"
                     /locus_tag="HGD76_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06345"
                     /product="transporter suffix domain-containing protein"
                     /protein_id="WP_168695278.1"
                     /transl_table=11
                     /translation="MQKFGLVLIIISFLPWLIIAVIVPFLPISLAQKAILVPALLVLAE
                     VLFWPGTLLVGKEVVQKYRRYLNFRYLNILVKRWKRKNRKR"
     gene            7180..7473
                     /locus_tag="HGD76_RS06350"
                     /old_locus_tag="HGD76_06350"
     CDS             7180..7473
                     /EC_number="4.2.1.96"
                     /GO_function="GO:0008124 -
                     4-alpha-hydroxytetrahydrobiopterin dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006729 - tetrahydrobiopterin biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016952722.1"
                     /locus_tag="HGD76_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06350"
                     /product="4a-hydroxytetrahydrobiopterin dehydratase"
                     /protein_id="WP_168695279.1"
                     /transl_table=11
                     /translation="MAAQKLSEAELTLALNSLPGWQIKEGKLYKEYKFSSFATALGWMV
                     SVGVHAEKMGHHPEWFNVYNTVKVNLVTHDIGNAISDLDVELAKKMEEIYHP"
     gene            complement(7643..8674)
                     /locus_tag="HGD76_RS06355"
                     /old_locus_tag="HGD76_06355"
     CDS             complement(7643..8674)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079163.1"
                     /locus_tag="HGD76_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06355"
                     /product="hypothetical protein"
                     /protein_id="WP_168695280.1"
                     /transl_table=11
                     /translation="MQDTDSMNDIAAALQQPADLDFALPDPEDEQIPESDFLQQLDVAW
                     QVCDRFDLQTEIWRGRILRAIRDREKKGGDGRGAGFLKWLKEREISKTQAYSWIQLANS
                     ADTLISDGKLNPDTVNNFSKRAFVETAKASPEVQQMVSEAAEKGDRITRREVRQLSDEW
                     TAMSSDLLPEEVREKAADNSLPPRYIAPLVKEMEKLPELHQKALQRDIAANPDVDTVKQ
                     ATSEARQLAKYLKSAAQVQALIAEDVDIETALEEAQRVGCLSIAADLVNQASQIEQTIG
                     KLYMTWKKISSLSDRLYVDTGASTPNLRSLLTCIEPLGGEIMELQLSGTTEHTIRLQIQ
                     ETS"
     gene            8996..9871
                     /gene="folD"
                     /locus_tag="HGD76_RS06360"
                     /old_locus_tag="HGD76_06360"
     CDS             8996..9871
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079164.1"
                     /locus_tag="HGD76_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06360"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_168695281.1"
                     /transl_table=11
                     /translation="MKQTAKILDGKALADKIQQELSETIAKLQSKIGRSPGLAVLMVGD
                     NPASAAYVRNKEKSCAKVGITSFGKHFPPETSQTELEEVIAQLNADDQVDGILVQLPLP
                     NHLDAVSLLHQIAPDKDADGLHPVNLGRLVRGETGLRSCTPAGVMRLLAEYRIPLQGKK
                     AVVVGRSILVGKPMALMLLAANATVTIAHSKTQDLQDITKDADILIAATGIPGMINAQM
                     VKPGAVVVDVGINRVTDSNGKSRLVGDVQFEAIANVAEYITPVPGGIGPMTVAMLLQNT
                     VSSYLQTTGN"
     gene            10001..10939
                     /gene="crtE"
                     /locus_tag="HGD76_RS06365"
                     /old_locus_tag="HGD76_06365"
     CDS             10001..10939
                     /EC_number="2.5.1.1"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0033386 - geranylgeranyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="crtE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010994390.1"
                     /locus_tag="HGD76_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06365"
                     /product="geranylgeranyl diphosphate synthase CrtE"
                     /protein_id="WP_168695282.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.4e-64, bitscore:
                     213.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVATDKRLETPKKSESASFNLATYLKQRQQLCEQALDNSITVVYP
                     EKIYEAMRYSLLAGGKRVRPILCLATADMIGGTIEMAMATACAVEMIHTMSLIHDDLPA
                     MDNDDYRRGKLTNHKVYGEDVAILAGDGLLALAFEHVAAQTPTNVPRDRVLQVIIRLGK
                     ALGAAGLVGGQVVDLESEGKSDISLETLNFIHNHKTAALLEACVVCGGIIAGASAEDVQ
                     KLTRYSQNIGLAFQIIDDILDITATQEQLGKTAGKDLTAQKVTYPSLWGIEESRAKAQH
                     LVAEACAELASYGEKAIPLQALAHFIISRNN"
     gene            11033..11488
                     /locus_tag="HGD76_RS06370"
                     /old_locus_tag="HGD76_06370"
     CDS             11033..11488
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015207140.1"
                     /locus_tag="HGD76_RS06370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06370"
                     /product="divergent PAP2 family protein"
                     /protein_id="WP_015079166.1"
                     /transl_table=11
                     /translation="MQDIGEIVNNRVLLVALVACFVAQGLKLIVELVKHRKLNVRVLVT
                     TGGMPSAHSALVTALADGVGQTLGWASPEFALATVFAIIVMYDAAGVRQAAGKQAKILN
                     QMIDELFHEKPDFFQDRLKELLGHTPVQVIAGSVLGVAISWLARAVY"
     gene            complement(11552..12205)
                     /locus_tag="HGD76_RS06375"
                     /old_locus_tag="HGD76_06375"
     CDS             complement(11552..12205)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079169.1"
                     /locus_tag="HGD76_RS06375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06375"
                     /product="hypothetical protein"
                     /protein_id="WP_168695283.1"
                     /transl_table=11
                     /translation="MQILTILPSALLLAVTPLISNINPVIAQQNLTNCQPPNAGEYLLL
                     VVSPTTENQKQLRSALPTELKTVTCKYNNQTVTRIGGFKNIDDANRWARYIQNIVGLSA
                     IITTRATQQAPQQAPQTTPKLPTSKITYNPKILGEGYAILVDYFNRPEMVSSLQKSVEG
                     NVGFVSYGQRPYLLAVYTTNQKEAYNTLQKLSESGFVAILADGRKVVLLRSTVR"
     gene            complement(12327..12656)
                     /locus_tag="HGD76_RS06385"
                     /old_locus_tag="HGD76_06385"
     CDS             complement(12327..12656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016875706.1"
                     /locus_tag="HGD76_RS06385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06385"
                     /product="MgPME-cyclase complex family protein"
                     /protein_id="WP_168695284.1"
                     /transl_table=11
                     /translation="MQTYYYVLASQHFLMEQEPIDEVLKERTRNYHEQEKEIDFWLVKQ
                     PAFLETPKMAGIKKKCPQPAAAIISTNSQFITWLKLRLEYVITGEFSAPSDTIPNPLAS
                     LIRVS"
     gene            complement(12810..13529)
                     /locus_tag="HGD76_RS06390"
                     /old_locus_tag="HGD76_06390"
     CDS             complement(12810..13529)
                     /GO_process="GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015215284.1"
                     /locus_tag="HGD76_RS06390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06390"
                     /product="ester cyclase"
                     /protein_id="WP_168695285.1"
                     /sec_met_domain="PF07366 (E-value: 2.2e-07, bitscore: 28.9,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQQSNNLPLWVQDRNKVIAASTDAQWRNQKPPDYSRSQQNLAK
                     ESIHHHLEGTLEAIVENLVRTFEMEVSWKTNPAQWLSIVNDKFRVTSNGGQEYTAAELG
                     KSGTYNLFMADSEHYKASEESFESSHDIFHSTFPQGFPWEVLAVYSSPPNVTFKWRHWG
                     HFQGKYKDYAPTGKTVEIIGMSVAHVTEDLKIVSLEHYFDNALFLESLTAGGKLENSEN
                     KSGGCPFGSWFQGLKKS"
     gene            complement(13664..14389)
                     /locus_tag="HGD76_RS06395"
                     /old_locus_tag="HGD76_06395"
     CDS             complement(13664..14389)
                     /EC_number="2.6.99.2"
                     /GO_function="GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013190727.1"
                     /locus_tag="HGD76_RS06395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06395"
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="WP_168695286.1"
                     /transl_table=11
                     /translation="MPTLGVNIDHIATIRQARRTVEPDPIAAAVLAELAGADGITAHLR
                     EDRRHIQDRDVRLLRQTVRTHLNLEMAATPEMLAIALDIKPDYVTLVPEKREEVTTEGG
                     LNIVGQIARIGEIVDKLQNAGIPVSLFIDAEPPQIEASVKVKAKFIELHTGQYAEAKDE
                     TTRQKELTLLAQGCEQAIKAGLRVNAGHGLTYWNVYPIAALPGMEELNIGHTIISRAAL
                     VGIERAVREMKEAMSLRSN"
     gene            14514..15176
                     /locus_tag="HGD76_RS06400"
                     /old_locus_tag="HGD76_06400"
     CDS             14514..15176
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079173.1"
                     /locus_tag="HGD76_RS06400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06400"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_168695287.1"
                     /transl_table=11
                     /translation="MLLELQQIIVNPGQQMLLKDISWQKLENILEEMGERRAARISYSD
                     GWLEIMVPLPEHEKDKEIFGELVRILLDKLEIDFEPFGSTTLKNERMRQAVEPDTSFYI
                     QNQAAVIGKNRIDLNIDPPPDLAIEIDITSRTRFDNYEILGVPELWRYQQQVLEIFLLR
                     EGKYIKSQSSPNFPNIPIIELVNEYVRQCLTIGRSQAMRNFRNWVKDNLYTQNGLIV"
     gene            15566..16699
                     /locus_tag="HGD76_RS06405"
                     /old_locus_tag="HGD76_06405"
     CDS             15566..16699
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015078025.1"
                     /locus_tag="HGD76_RS06405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06405"
                     /product="ISAs1-like element ISAsp2 family transposase"
                     /protein_id="WP_168694588.1"
                     /transl_table=11
                     /translation="MKLPPKITIVDHFKDLEDKRVERTKRHKLIDIVTIAICAVICGVD
                     SWVLMEAYGKKKEKWLKQFLELPNGIPSHDTFARVFARIDPQQFQNCFLSWIKSINKIT
                     EGEVIAIDGKTLRHSYDKGKDKGAIHMVSAWATSNKLVLGQCKVEEKSNEITAIPELIK
                     VLDIAGCLVTIDAMGCQKEIVKSIAEKSGEYIIALKKNQGNLYKNVEEIFKEAISKGFE
                     GFKYSEFHTKEDKHGREEIRHYLMLSDIEERIDTDKKWVNLQSVGMVEYIRKVNGKTKV
                     ETGYYISSLTNNAKLLGESVRTHWGIENSLHWVLDVAFREDDCRIRKDNAPQNFAVIRH
                     IAVNLLGKEKSQKLGTKSKQFCAGWDDEYLEKILECI"
     gene            16965..17336
                     /locus_tag="HGD76_RS06410"
                     /old_locus_tag="HGD76_06410"
     CDS             16965..17336
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018933.5"
                     /locus_tag="HGD76_RS06410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06410"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_210967734.1"
                     /transl_table=11
                     /translation="MRFPCMLRRCQVKTDEKTGRFLKNGQSRKKGLNRSISDASWSDLI
                     LKIEYLAVKQGKVVIKINPKYSSQECRNCGHTDKSNRDGEKFICTECGYHEHADIGAAK
                     TIRDRGFKIVRGDSAKLAV"
     gene            17553..18335
                     /locus_tag="HGD76_RS06415"
                     /old_locus_tag="HGD76_06415"
     CDS             17553..18335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079176.1"
                     /locus_tag="HGD76_RS06415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06415"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_233467079.1"
                     /transl_table=11
                     /translation="MTTEKNLAIVDREVHDSSTYYVFDDGETHDPPTDLIFDDGEPLES
                     YRHRTGMNVLIRSLQQLWCDRNDYFTGGNMFIYYSSTQVRNRDFRGPDFFAVLNIDGTN
                     TRQGWVVWDENGRYPDVIVELMSPSTAAIDKGIKKDLYEQTFRTSDYFVYDPFNPRSLQ
                     GWHLDDNQKYQPLIPNEHGWLWSRRLGLWLGTWEGTVERETTIWARFYDVAGNLVLLPE
                     EAAKSQAKAAKAREEEAKAKADRLAARLRELGEDPDIL"
     gene            complement(18446..19228)
                     /locus_tag="HGD76_RS06420"
                     /old_locus_tag="HGD76_06420"
     CDS             complement(18446..19228)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016952894.1"
                     /locus_tag="HGD76_RS06420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06420"
                     /product="ABC transporter permease"
                     /protein_id="WP_168695288.1"
                     /transl_table=11
                     /translation="MARYLKVLRLFWNAAIAAEMEYRINFIISAFSSLGNLVGSIFGLF
                     LFYRTGYTFTGWSWDAALVVLGIFTLLQGFSSTFLAPNLNRIVRHVQEGTLDFVLLKPI
                     RSQFWLSIHTLSLWGIPDLILGLLIIGYAGRKLNLGIDKYLLTIFPLACGLVILYSLWF
                     ILSATSIWFVKIYNVTEVLRGFLDAGRYPITAYPAAYRFFFTFIVPVTFLTTVPAQSLL
                     GQIQFTWWLGAGFLAIVLFFISTQFWRFALRFYTSASS"
     gene            19355..19957
                     /locus_tag="HGD76_RS06425"
                     /old_locus_tag="HGD76_06425"
     CDS             19355..19957
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015079178.1"
                     /locus_tag="HGD76_RS06425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HGD76_06425"
                     /product="DedA family protein"
                     /protein_id="WP_168695289.1"
                     /transl_table=11
                     /translation="MHFNLPELIKSLGYFGVWGIIFAESGLLIGFFLPGDSLLFTAGFV
                     ASQNLLNIWVLIFGAFFCAVLGDNVGYFTGHKFGRKLFEKDDSWLFRKKHIVKTQDFYE
                     KHGKKTIVLARFMPIVRTFAPIVAGIGAMHYRSFMSYNLIGGFVWTFGITLLGFFLGKT
                     LPAEQLDKYLLPIIGLIVVVSLFPSVIHIIKENRANK"
ORIGIN
        1 taccatcccc aacacctagg aggaacagga caaaccctag attggctaat gttaaatcag
       61 gaatttagcc cctctctccc ttggttctta gccggaggac tcacaccaga taatattttg
      121 actgctttaa gtcaaattaa accccatggt attgatctat ctagtggtgt cgaacactca
      181 ccaggtaaca aagatttaga taaagtagcc ctattatttc aaaatctagg gaataggtaa
      241 ttggtcagtt gtcagtaggg gcgaagcatt tggaagataa attatcggtc attgccaaaa
      301 atagttctcc aaatgcttcg cccgtacagt tgtcagttga aaaaatctgt tccctgttcc
      361 ctgctccccg ttccctgttc cctgttccct cattaaaaga atgacggttg gtgacgaatc
      421 aagctgaaga attcttcacg ggttttctgt tcttcctgga atactcctac cattgaactg
      481 gtaactgtcc aagaaccagg tttttgcact ccacgcatta ccatgcacat atgactggct
      541 tccatgacga cagcaacacc tttaggttcg agaacggttt gcagtgcttc agcaatttgt
      601 cgagttagtc tttcttggac ttgtaaccgg cgagaataca tttccacaat ccgtgctagt
      661 ttacttaatc ccaccacttt ttgattggga atataagcca cgtgcgctct acccataaat
      721 ggcaacatat gatgttcgca taagctaaag aagttaatat ctctaactaa caccatttca
      781 tcatgtcctt catcaaaaat agcaccattg atgaggtctt ctaaagattg attatagcca
      841 ctggtaagaa acttcatcgc cttagctacg cgcttgggtg ttttcagaag tccttcccgt
      901 tcaggatctt ctcctactcc cacaatcatt gttcgcaccg ctgccatcat ttcatccatg
      961 atttcctcag atggtggatg tatttgtggt tctttgccat tatgggtatt gcggtctggt
     1021 cggacattga tagcttctgc taaatcagga atgagaggtg attgggaagt gttagaaccg
     1081 tttgaaccag cgatagtcat gattgaattt tagtaatttg tcagttgtca gttgtcagta
     1141 ggggcgaagc atttggaaga taaattatcg gtcattgcca aaaatagttc tccaaatgct
     1201 tcgcccgtac agttgtcagt tgtcagtagg ggcgaagcat ttggaagata aattatcggt
     1261 cattgccaaa aatagttctc caaatgcttc gcccgtacag ttgtcagttg tcagtagggg
     1321 cgaagcattt ggaagataaa ttatcggtca ttgccaaaaa tagttctcca aatgcttcgc
     1381 ccgtacagtt gtcagttgtc agtaggggcg aagcatttgg aagataaatt atcggtcatt
     1441 gccaaaaata gttctccaaa tgcttcgccc gtacagttgt cagttgtcag taggggcgaa
     1501 gcatttggaa gataaattat cggtcattgc caaaaatagt tctccaaatg cttcgcccgt
     1561 acagttgtca gttgtcagta ggagcgaagc atttggaaga taaattatcg gtcattgcca
     1621 aaaatagttc tccaaatgct tcgcccgtac agttgtcagt tgtcagtagg agcgaagcat
     1681 ttggaagata aattatcggt cattgccaaa aatagttctc caaatgcttc gcccgtacag
     1741 ttgtcagtgg taattaaaga gataaatgat aaaatcacca attagagaac accagcattg
     1801 gacataatcg tcaattcttg aattactgct tcttgtggta ataagacagt gtgcagaatt
     1861 gttgttgcca caatttctgg agttaacatt tgggaacggt caaagttagc ttggactgtc
     1921 ggtgtatccc aaatttccgt attcacagaa ccaggacaaa tggcaatgac gcgaatgcca
     1981 ttagcacgtt cttcttgtgc gagggtttgg gataggaaaa gaagtcctgc tttgctgacg
     2041 cagtaagcgc cccaacccgg aaaagcttgt ttgccagcta tagaggcaat attaataatt
     2101 gtgccttggc cttgttggcg cattcctggc aaaattccca tcatgcactg aaagacactg
     2161 gtgagattta aattaattac ctgttgccag tcttctaaag gtgtttcact caggttgccc
     2221 gtatatccaa tcccagcgtt attgatgaga atatttatgt tgccaaattc gtcagctatt
     2281 ccttgaattt tggatttaac ctgggtaact tcagctaagt ctacacaaaa ggctttggct
     2341 tctactccta actcctgtgc agctttagct acggactcta gtttatcctg agaacggctg
     2401 accaatgcta catctatccc agccttggca aatgccaaag ctgttgcttt gccaattccg
     2461 ctactagcac cagtaattaa ggcgcgtctt ttttgctcaa aattcatgat attttccaac
     2521 tttttggcaa tgctgtcagc caacagatgc tcataaaccc aagtaagtcc taatgcctat
     2581 agctcttgaa gattgttaaa aatctttaag cagccatagg caattatagc attgctgtga
     2641 ttctatgcca ttttcttgag tatttttagt gagcaagttc tgtgaaaacg ccgatattac
     2701 ggaatttatc ataacggagt tggcgacgtt cagcaggtgt cagacggttc agttcgtcta
     2761 agttttctag caaggcttgt ttcaagtttg tcgctgctgt taaagggtct gagtgtgcgc
     2821 cacccaaggg ttcagggaga atttggtcaa taatgcccaa gtttttgagg tcgtgggaga
     2881 taatttttaa ggctacggcg gccaggtgag atttactggc atctttccac aaaattgcag
     2941 cgcaggcttc cggggtagcg acggtataaa ctgagtgttc aaacatcaat aggcgatcgc
     3001 ctacaccaat acctaacgcc ccaccagaac caccttcacc aataactgtg caaatgatgg
     3061 gtacgtcaaa actgaacatt tcccgcaggt tataggcgat cgcttctcct tgtccttggt
     3121 gttcggcttc tatgcctgcc caagccccag gagtatcaat aaaggtcaaa attggcatac
     3181 taaacttatt ggcgtgttcc atgaggcgca gagccttacg atagccacca ggagcagcca
     3241 tgccaaagtt acgagccacg ttatctttag tatcccggcc tttttgatgt cctaacatca
     3301 tcacaggttg tccagctatg cgcccgacac cacccactaa agccggatca tctccgccac
     3361 agcgatcgcc atgcaactcc atccattcat cactaataga ttgaatataa tctaaagtgc
     3421 tagggcggcg gggatgacgg gctacctgca atcgttgaga tggtgtcaga ctgctaaaaa
     3481 tctcttcccg taattgcgtc gcccttgtct ctagttggcg aatttgtcca gaaacatcaa
     3541 caccattttc ttcagccagt tggcgaattt ggtcaatgcg agtggccagt tctgctaaag
     3601 gcttttcaaa atctaacagt agcggtttgc gctcagtggt tgccatagtt atgttagttg
     3661 tcagttgtta gttgttggtt gtcagttgtc agtcgtccgt tgtcagttgt tagttgtctt
     3721 ttctttgcca ctgaccactg accactgact aatgactaaa ctagcaatgg tctaaaaccg
     3781 tgtttaatgg acacacgacc aatttgctcc attttgtcta cggtaatctg attacgcccc
     3841 caagaaaagt ttgtatataa cttctcaaat tccaatagca ttgattctgc aaaacaagca
     3901 aataattgcc gacctggcac atccatattg acaattttca taattttcca gtcaatatct
     3961 agggaatgct ccacaatgcc accatttaac acatacaccc ctgggtgctg aatttttgtg
     4021 cctaagtttt taggatagcc accatcaatc aatagacagg gttgttttaa tgttctcggg
     4081 tcaatttcta cgcctttggg catactcgcc acccaaacga caatatccgc ttggggtaat
     4141 gcttcctgta atcccatgat tttaccgcgt cctagttctg cttgcagttc ttggagacgt
     4201 tcttgatttc tagcaattaa tagtaattct tggacatctg tttttttatc tagccagcgg
     4261 gtgactgcgc taccaatatc ccccgttgca ccgcacacag ctacagttgc tttggacaat
     4321 tcaatcccta gttgtttaga ggcttcttct acttgccgac aaataatgta agctgtatga
     4381 gtattgcctg tggtgaagcg ttcaaaatct aggttaatat tgcggacttg tttgaactgc
     4441 tctaaattaa agttctcaaa aataattgag gaaaatcctc ccaaagctgt aatatcaatg
     4501 ccatgctttt gagcatgagc catagcgttg agaattttcc gcgtggcagc tttaatacga
     4561 cgattggcca gcatttctgg caaaaagcaa gattctacat actttccttc tattttctgc
     4621 ccggtgatac tggtgacagt gatatgatca actatttgcg gcggggcgct acaccaaaag
     4681 tctagccctt gatcggcata ttctggatat cccaattctt gagctactga ttgagcgtgt
     4741 tctaaactag tcagatgtcc aattaaacca aacatggagt gatatattag gcgtgtgctg
     4801 tcgtgcaaaa ctgtggaatt agtgggcaat accaactttg gatttgagat tttggatttt
     4861 ggagaaatcg caaactatag tatctaacta ttaaaaatac tacataaggg gtcaatgttc
     4921 acagttgacg gttgactaca gaactattac tcccctacct cccctacttc ccctacctcc
     4981 cctacttccc ctacctcccc tacttcccct acctccccta cttccctggg gtaacaaagt
     5041 cgtcacccct gtgggcagtt attaaacggt tgccagtccg taggcagaaa gacgcatgat
     5101 gtcacgggtg gtaaagccaa tgttacttag tgcttcaccg tattgaatca taaagtcttc
     5161 tactaaagca tctttttcca ttgctaagac tttggcatcg tctgctactt cgttcagcat
     5221 tttccagaca atgggcagat tttggcggtt tgctgcttct aattcggctt gagattctgt
     5281 aaagttttct tgcaaccaca cttcaccaaa gttaagatgg ctgtattctt cttttacaac
     5341 tccttctgtg attttacgag cgaaatcatc agctacggga atgtagatat tataggcagc
     5401 gatcgcaaaa cattcgataa ttaatgattg aatcaaaagg caagtaacga ctttaccttc
     5461 ttcggctgcg gtttgaaaat tgtcgtgtag tcccaagaaa aactttttag cgaatactaa
     5521 atctggagtc acttttaaat tccgtccaca ggcttcaaaa ccttttttgt ggcgactttc
     5581 cattttcgag agacgaatta attcctcttc ctgtgctggc agcagtttcg ctaatgtaat
     5641 gtaattttcg tgggcctctt gttccccctc aatgacaatg gcattgatgc ggctataagc
     5701 atctttatat atttcgcttt ggaaatcaat tttttcaatt tggtctacaa gctgctgcat
     5761 attcggtgtt actccgttgt ccatgaatta tttaatacaa aaacttaaat tacccgatca
     5821 atttggggta attatcactg tgatttaatt taacttaaca agaaactata gttattaaat
     5881 tagtttttac tgatggttgt actaccagaa aaacaaatgt atggagtcat agccaatgtc
     5941 caagctaaac tggaatctaa aaaaatgcca atttgttgag cctgttagta gcgctaacaa
     6001 gtgcatttat agggttactg ccgctaattg tggtttttct gacctctttg ggggggtgag
     6061 aaacagcagg gggtggccac aataattgga ctttagccaa ttaccggggg gtagggacaa
     6121 gggaagtttt tactggcctt tgctaattct accttagtag cgatcgcagt tacggctttt
     6181 ccaattttca cttcggcttg atcttaattg gtgagtggaa tgattgattt aaacctttag
     6241 tatttacaac caggttggaa ttaagcaaag tatagttggc tttattggag ttataagagc
     6301 agtttaccaa tagttgttcg ttagtgatag cagcagtgac aattgctacg atagccgttt
     6361 aaaatcatag tatataatcc agatcaggag gtaatcatac aatggctaac atagaacatt
     6421 atcgtcagtg tattcaaacc atcctcaaag aacatggtaa atttaagccc aaatatgacg
     6481 aaatagataa tgaactaatt tttgatacta ctcatgatca ttatcaactt atgcgtgttg
     6541 gttgggatga tttaagaagg gtttatcata gtgtcattca tttcgatatt aaagataaca
     6601 aaatctggat tcaacaaaat atgacagaat cagatttagc tcaagaactt gtaaatatgg
     6661 gaatacaaaa agaagatatt gtttttggtt tacaaccacc ctacaaacgc ccttatactg
     6721 gttatggtgt agcttgattt ttgaatgctt cagttgtcag aatcaggatt tctttccttt
     6781 gaatgaaaca aaaaaaccta caatgtaagt taaaccactc cagctaaaca tacaaaaata
     6841 ctaaactcag attccgtcat cattagaaaa tatgcaaaag tttggtttag tgttaattat
     6901 catctcattt ttaccgtggc tgatcattgc tgtgatagtg ccatttttgc caatttctct
     6961 cgcccaaaaa gctatattag ttccagcgtt attagttttg gctgaagttc tattttggcc
     7021 aggtactctg ttggtgggga aagaagtagt gcaaaagtat cgccgttatt taaatttccg
     7081 ttatctaaat atactcgtca aaagatggaa gcggaaaaat agaaaaagat gataattagg
     7141 tagaatcagt atttataaat ctctatgtag gttaggaaaa tggcagcaca aaaattgagc
     7201 gaagcagaac taacattagc cctcaatagt ttaccaggat ggcaaattaa agaaggtaaa
     7261 ttatacaaag aatataaatt tagctccttt gcaactgcgt taggttggat ggttagtgtg
     7321 ggtgttcatg cggaaaaaat gggacatcac cccgaatggt ttaatgttta caacacagtt
     7381 aaggtaaatc ttgttactca tgacatcggt aatgctatca gtgatttgga tgtagaactg
     7441 gcgaagaaaa tggaggaaat ttatcatccg taattctaaa agcccgcctg ggaatgaatt
     7501 cccagtctca tagcaaaagt catctaaaga tgactaaaaa tacttagttt acttgagtaa
     7561 actttggcta ttagccctga tagcgtagcg tggcgtaagc cataattcat ttcagggcgg
     7621 gtgtgtaaat ccctacaaat gattaactcg tttcctgaat ctgtaatcta attgtgtgtt
     7681 ctgttgtacc gcttaattgc agttccatga tttcgccacc gaggggttct atgcaggtga
     7741 ggagcgatcg caaattaggc gtacttgcac cagtatctac atataacctg tccgataaac
     7801 tactaatttt tttccaggtc atatacaatt tgccaatggt ttgttcaatt tgcgatgctt
     7861 gatttaccaa gtcagcagca atgcttaaac aaccgactcg ttgagcttct tctaatgcag
     7921 tttcaatatc tacgtcttcc gctattaacg cttgcacttg agccgcagat ttgagatatt
     7981 tggctaattg tcgggcttct gaggtagctt gtttgacagt atcaacatca ggattggcgg
     8041 ctatatccct ttgtaatgcc ttttggtgca attcgggcag tttttccatt tccttgacca
     8101 gaggggcaat gtagcgcggt ggcagactgt tatctgcggc tttttcccta acttcttctg
     8161 gtaataaatc ggaggacatg gctgtccatt cgtcactgag ttgacggact tctctgcggg
     8221 taatgcgatc gcctttctcc gcagcttcac tgaccatctg ttgtacttct ggagacgctt
     8281 tggcggtttc tacaaatgcc cgtttactaa agttattaac cgtatctggg ttcagtttgc
     8341 catctgatat caaggtatca gcactattgg ctaattgaat ccaactatag gcttgagtct
     8401 tactgatttc gcgttctttg agccatttaa gaaaacccgc accgcgtcca tctccgccct
     8461 ttttctctcg gtcacggata gcgcgtaaaa tgcgaccacg ccaaatttct gtttgtaaat
     8521 caaagcgatc gcatacctgc catgctacat caagttgttg taaaaagtcg gactcaggaa
     8581 tttgttcatc ttctggatca ggtaatgcaa agtctaaatc tgctggctgt tggagtgcag
     8641 cagcaatgtc attcatagag tcggtatctt gcacgatgga tagctggttg gggtatgcga
     8701 tttagcttat attcacgcaa tttactattt tgacaattgg tgaatcaagc aagtaagtat
     8761 tttactttaa aaattaaatt ttaggggact gggaaaatga gaaaatgaag ggacgaaagt
     8821 gcagaacaga caaaaataac aggacttacg gaaaatatct ctgaaaccct catttctccg
     8881 tgtcctctgt gactctgtgg tatggctaac gccacgcttc gctatcgtta ttccgtgatt
     8941 tgtgcgtaag cactaaataa gaaacaattc tctgtcacct gtcacctatt cccttatgaa
     9001 acaaactgcg aaaatccttg atggtaaagc attagccgat aaaattcagc aagaacttag
     9061 tgagactatt gccaaattac aaagtaaaat tgggcgatcg cctggattag cggtattaat
     9121 ggtgggagat aaccccgcat cagccgctta tgttcgcaac aaagaaaaat cctgtgccaa
     9181 agtcggaatt acctcttttg gtaaacactt tcctcccgaa accagccaaa ccgaactaga
     9241 ggaagtaatt gcccaactca acgcagatga tcaagtagat gggattttag tccagctacc
     9301 ccttcccaat catttagatg ctgtcagtct actacatcaa attgccccgg ataaagacgc
     9361 tgacggactc caccctgtga acttaggaag actggtacga ggtgaaaccg gtttacggag
     9421 ttgtactcct gccggtgtga tgcgattgtt agcagaatat agaattcctt tacagggcaa
     9481 aaaagccgta gtcgtaggac ggagtatttt agtagggaaa ccgatggctt tgatgttatt
     9541 agcagctaat gccacagtca caattgccca ttccaaaacc caggatttac aagatattac
     9601 caaagatgcg gatattctca ttgctgccac cgggattccg ggaatgatta atgcccagat
     9661 ggtaaaaccg ggcgcagttg tggtagatgt gggaataaat cgggttacag atagcaatgg
     9721 taaaagtcgg ttagttggtg atgttcagtt tgaagcgatc gctaatgtgg cagaatatat
     9781 tactcctgtt cctggtggta tcggtccaat gacagtagcc atgttattgc aaaatactgt
     9841 ttctagctat ttacaaacca caggcaactg agaaataatt tttgtgaata ttcatgatta
     9901 ctcaccaaaa ccgtgagtgt ttccgcccca aagccccgta aaattggtaa acagatcaca
     9961 aacagcccaa tattttgaac agtcaagagg aatacaaagc atggtagcaa cggataaaag
    10021 attggaaacc ccaaaaaaat cagagtcggc tagttttaac ctcgctacct atctcaaaca
    10081 acgacaacag ctttgcgaac aggctttgga taattccatt accgtcgttt atccagaaaa
    10141 gatttatgaa gccatgcgct attctctctt agctggaggg aaacgagttc gtcctattct
    10201 ctgtcttgcg actgctgaca tgattggtgg cacaatagaa atggctatgg ctacagcctg
    10261 tgcagtagaa atgatccaca ccatgtcatt gattcatgat gatttacccg ccatggataa
    10321 tgatgattat cgtcgcggta aactcacaaa tcataaagtt tatggtgaag atgtggctat
    10381 tttggcagga gatggtttat tggctttagc ttttgaacac gtagccgccc aaactcctac
    10441 aaatgtacct agggatagag ttttacaagt catcattcgc ctgggtaaag ccttgggtgc
    10501 ggctggctta gtcggtggtc aagtggtaga tttggaatcg gaaggtaagt cagatatttc
    10561 cttagaaacc ctgaatttta ttcataatca taaaaccgca gctttgttag aagcttgtgt
    10621 agtttgtggg ggaattattg ctggtgcatc tgccgaagat gtgcaaaaat taactcgtta
    10681 ttctcaaaat atcggtctgg ctttccaaat cattgatgat attctggata tcactgctac
    10741 ccaagagcag ttaggtaaaa ccgctggtaa ggatctcaca gcccagaaag tcacctatcc
    10801 tagtctgtgg ggaattgaag aatctcgcgc taaagctcaa catttagttg ctgaagcttg
    10861 tgctgaatta gcatcctatg gtgaaaaagc cattcctttg caagcgctcg ctcactttat
    10921 catcagccgc aataactaag cccaattgtg gattttaact aaattttggc ttctactgcc
    10981 gtttttcctc catacaatca ctgcttacac ttactaactt caccaaaata ccatgcagga
    11041 cataggcgaa attgttaaca accgggtgct gctggttgcg cttgtagctt gttttgtagc
    11101 tcaaggatta aagcttatcg ttgagttagt caaacatcgt aaattaaacg tgcgtgtttt
    11161 agtaactact ggaggtatgc ccagcgccca ttcagcccta gtaacagccc tagcagacgg
    11221 tgttggccaa actttaggtt gggcatctcc agaatttgct ctagctacag tttttgctat
    11281 catcgttatg tatgatgccg ctggagtgcg tcaagctgct ggtaagcaag caaaaatcct
    11341 caatcaaatg attgatgaat tattccatga aaaaccggac ttttttcaag accgtctcaa
    11401 ggaattatta ggacatacac cagttcaagt tatcgctggt tcagttttag gtgtagctat
    11461 ttcttggtta gcacgggctg tttattagtt attggtcatt ggtgaacaaa caacgaacaa
    11521 ctgacaactg acaactgaca actgacaact cttaacggac ggttgagcgc agtaacacta
    11581 ctttgcgacc atctgctaat atggctacaa atccgctttc gctgagtttt tgtaatgtgt
    11641 tatatgcttc cttttgattg gtagtataaa ctgccaacag gtaagggcgt tgtccatagg
    11701 agacaaaacc cacattacct tctacggatt tttgcaggct actaaccatt tctggacggt
    11761 taaaataatc aaccagaatt gcataacctt cccctaatat tttggggtta taggtgattt
    11821 ttgaagttgg taattttggt gttgtttgag gtgcttgttg aggtgcttgt tgtgtagcgc
    11881 gagtggtaat aatggcagat aaaccaacta tattctgaat ataccttgcc cagcgattgg
    11941 catcatcaat atttttaaac ccaccaattc gcgttactgt ttgattatta tatttgcaag
    12001 taactgtttt taattcagtc ggtaatgcac tacgcaactg cttttgattt tcagttgtgg
    12061 gacttactac taataataaa tattctcccg catttggtgg ttgacaatta gtaagatttt
    12121 gttgagcaat aacaggattg atattgctaa ttaagggagt aactgctagt aataaggcac
    12181 ttggtaagat tgttaatatt tgcataaatt ggtaattggt aattggtaat tggtaattgg
    12241 taattggtaa ttggtaattg gtaattgggg aagaggtgaa attcttatat attccccgtt
    12301 ccccgttccc cgttctctgt tccctattaa gaaaccctaa taagggatgc taatggattt
    12361 ggtatagtgt cgctaggggc ggagaattct ccagtaatca catactctaa ccgcagtttt
    12421 agccaagtta taaattgcga attggtggaa ataatggctg ccgcaggttg gggacatttc
    12481 tttttaatac ctgccatttt tggtgtttct aaaaaagcgg gttgcttaac taaccaaaaa
    12541 tcaatttctt tttcttgttc atgatagtta cgagtccgtt ctttgagaac ttcgtctatc
    12601 ggttcttgtt ccataagaaa gtgttgactg gccaaaacgt aatagtatgt ttgcattttc
    12661 tttgcttgct gactaatcta tagttttagg ttactgtggt aatatgcccg acttctagta
    12721 ttaattcatc atttattaac atcatgaaaa cagaagtcgg ggatctgcta taattttagg
    12781 gcgcagtgtt gaatctgtac cctgagcgat taacttttct tcaatccctg aaaccaagaa
    12841 ccaaaaggac aaccaccgct cttattttca ctattttcta gtttgccacc tgctgtcagg
    12901 ctttctaaaa atagggcatt atcaaaatag tgttctaagg aaacaatttt taaatcttcg
    12961 gtgacatgag caacactcat accgataatt tcaactgttt tccctgtggg tgcataatct
    13021 ttatacttac cctgaaaatg tccccagtgt cgccatttaa atgtaacatt gggaggacta
    13081 gaataaactg ccaatacttc ccagggaaat ccttgaggaa aggtactatg aaagatatca
    13141 tgggatgatt caaaactttc ctctgaagct ttgtaatgtt cagaatcagc cataaataaa
    13201 ttataagtac ctgatttacc taattcggca gcggtgtatt cttgaccacc attgcttgtt
    13261 acccggaatt tgtcattgac gatagataac cactgtgcgg ggttagtttt ccatgacact
    13321 tccatttcaa aggttctcac cagattttca actatagctt ctagtgtacc ttcgagatga
    13381 tggtggatac tctcttttgc taggttttgc tgagaacggc tatagtcagg gggtttttga
    13441 ttgcgccatt gagcatcagt gctggctgca attaccttgt ttctatcttg tacccatagg
    13501 ggcaggttgt tagactgttg agaagtcata gtaggttgaa gtttccaaat gtgactctaa
    13561 ttttctggaa ttacgcagct acaacccctc tggaagaaat tcaaaattga gaattaaaaa
    13621 ttaaaaaaga agaaaccctt tttaattttt aatttattaa tttttaattg gaacgaagtg
    13681 acattgcttc tttcatttcc cggactgctc tttctatacc tactaaagct gcccgactga
    13741 tgatagtatg accaatattg agttcctcca tgcctggaag ggcggcaatg gggtaaacat
    13801 tccagtatgt gagtccatga ccggcattca cccgcaaccc agctttaatg gcttgttcac
    13861 agccttgggc taataaagtt agttcttttt gccgagttgt ttcgtctttg gcttccgcat
    13921 attgccctgt atgtagttca ataaatttgg cttttacctt gacagatgcc tcaatttgtg
    13981 gtggttcggc atcaataaac aaactaacgg gaatgccggc gttttgtagt ttatcaacta
    14041 tctctcctat tctagcaatt tgtccgacaa tatttaaacc accttctgtt gttacttctt
    14101 cccgcttttc tggtactagg gtaacataat cgggtttgat atctagggcg atcgctaaca
    14161 tttccggggt tgctgccatt tctaagttta aatgggttct cactgtttgt cgcaatagcc
    14221 gtacgtctcg atcttgaata tgtcttctat cttcgcgcaa atgggcggta atgccatcag
    14281 cacctgctaa ttctgctaat actgctgctg ctatagggtc tggttctact gtccgccgtg
    14341 cttgacgaat ggtagcgata tggtcaatat taacaccgag tgtaggcacg cctggtttct
    14401 cctgtttaac ggttctcaga tgttaatttt acaggaaata ccaattctag gggtgaatgg
    14461 tcatattata aagaaagata attcttaaaa acttggataa tctttgaggc gatatgcttt
    14521 tagaactgca acaaattatt gtcaatcctg gtcaacaaat gttactcaag gatattagtt
    14581 ggcagaagtt ggaaaatatt ttagaagaaa tgggagaaag gcgtgcagcg cgtatttctt
    14641 atagtgatgg ttggttagaa attatggttc ctttacctga acatgaaaaa gataaagaga
    14701 tatttggtga attagtcaga attttattag ataaattaga aattgatttt gagccttttg
    14761 gttcgacaac acttaaaaat gaaagaatga gacaagctgt agaaccagat accagttttt
    14821 atattcaaaa tcaagctgct gtaattggca aaaatcgcat tgatttaaat atagatccac
    14881 caccagattt ggctattgaa attgatatta cttctcggac tcgatttgat aattatgaga
    14941 ttttgggagt tcctgaactt tggcgatatc aacaacaagt tttggagatt ttcttgttac
    15001 gggaagggaa atatataaaa tctcaatcta gtcctaattt tcctaatatt cctattattg
    15061 aattagttaa tgagtatgta cggcagtgtt taactattgg gagaagtcag gctatgcgga
    15121 attttaggaa ttgggttaag gataatttgt atactcaaaa cggcttgatt gtttgattct
    15181 aaacgtaggg gtttagcagt gctaaacccc tacacatctg ggttctttgt catttggcaa
    15241 aagtttaaat ctcacccgtg tttagtataa tcgctattta gtaaagttgt aaaattaagg
    15301 aattggcaca aactcgtatt tatcagttcc aggtttttgt tgaactttga tcaggaaact
    15361 aggatcatat ccaggggaaa cgcatctaat tttttttgac aaaatgtaac ttctatgaat
    15421 agataaaaag ggcagtatta ccatgttaat atcaagccaa taaatgagta tgaagaaaat
    15481 ttgatggtaa attcgtttct ataagaatca ataaaatgag ttgaagtggt attctcaata
    15541 aaactaaaga gacaaaattc acaaaatgaa gctaccacca aaaatcacaa tagtagatca
    15601 ctttaaagat ttagaagata aaagagttga gagaacaaaa aggcataaat taatagatat
    15661 agtaaccatt gcgatttgtg cagtgatctg tggagtagat agttgggtat tgatggaggc
    15721 ttatggaaaa aagaaagaaa aatggctaaa acaattttta gaacttccaa acgggattcc
    15781 atctcatgat acattcgcca gagtatttgc gagaatagat ccgcaacaat ttcagaattg
    15841 ttttttgagt tggataaaat ctatcaataa aattacagaa ggagaagtca tagcaataga
    15901 tgggaaaaca ttaaggcatt catatgataa aggaaaggat aaaggtgcga ttcacatggt
    15961 aagtgcatgg gcaactagta ataaattagt attaggacaa tgtaaagtag aagaaaagtc
    16021 aaatgaaata acagccatac cggaattaat taaagtatta gatatagccg gatgtttagt
    16081 aacgattgat gcgatggggt gtcaaaaaga gatagtaaaa tcaattgcag aaaaatcagg
    16141 cgaatatatt atcgcactca aaaagaatca aggtaattta tataagaatg tagaagaaat
    16201 cttcaaagaa gctatatcta aagggtttga gggattcaaa tatagtgaat ttcatacaaa
    16261 agaagacaaa catggaagag aagagattcg tcattatctc atgttatcag acatagaaga
    16321 aagaatagat actgataaga aatgggtaaa tcttcaaagt gtaggaatgg tagaatatat
    16381 acgaaaagtt aatggaaaaa cgaaggttga gacaggctat tatataagta gtttgacaaa
    16441 taatgcgaaa ttactaggag aatcagtccg cactcattgg ggtatagaga attcattaca
    16501 ctgggtttta gatgtagctt ttagagaaga tgattgtcgg ataagaaagg ataatgcacc
    16561 acaaaacttt gcagttattc gtcatatagc agttaatctt ttaggaaaag aaaaaagcca
    16621 aaaactagga actaaaagta agcagttttg tgcaggatgg gatgatgaat atttagagaa
    16681 gattttagaa tgtatctgat aaaaatcaga aaatatagac aaatataaat ataaccaatt
    16741 tatttttctg ttgattctac aatagaatct atatttttga tgccaaaaaa tatagatatt
    16801 aatatataga actgaacaaa ataaatccat cattaaaaat aaataattac tctaaattta
    16861 tgaaattttt ataattttaa taaaggaatt tatcagattt tgaatgaagt tagatatttt
    16921 cccatattga tgcactaata tagtattctg tcaagataat ttagatgcgt ttcccctgta
    16981 tgttgaggcg ttgccaagtt aaaaccgatg aaaaaacagg gagattttta aagaatgggc
    17041 aatctagaaa aaaaggatta aaccgttcta tttctgatgc aagttggagt gatttaattt
    17101 taaaaattga gtatctcgct gtaaagcaag gaaaagttgt aattaagatt aatcctaaat
    17161 actccagtca agaatgtagg aattgtgggc atactgataa gtcaaaccgt gatggtgaga
    17221 aattcatttg tacggaatgc ggatatcacg aacacgccga tattggtgct gcaaagacta
    17281 tcagagatag aggtttcaaa atagtacgtg gggactccgc gaaacttgct gtttaacagc
    17341 taaacgccca gaagatgagc cagtgcggtc ttggggtctc cccaagtaga gcaactggcg
    17401 gtatcagcac gcacttttgt gcaaacgtac tgagtctggg aacctgtgtg aacaggatat
    17461 taggattgta aaatcttaag aatccccgcg tctttagacc ggggagtgtc aatatagaag
    17521 tttaggcttg atgaaaaagg cgataatcac tcatgactac cgaaaagaat ctagccattg
    17581 tggacaggga agtccatgac tcatccactt attatgtgtt tgacgatggt gaaacccatg
    17641 acccaccaac agacttaata tttgatgatg gtgaaccctt ggaatcatat agacatcgga
    17701 ctggaatgaa tgtccttatc cgatcattgc agcagctttg gtgcgatcgc aatgattatt
    17761 ttactggggg caatatgttt atttattaca gcagcaccca ggttcgtaat cgtgattttc
    17821 gcggtcccga tttctttgct gttctcaata ttgatggtac taacactcga caaggttggg
    17881 tggtttggga cgagaatggt cgctatcctg atgtaattgt ggaattaatg tcaccttcta
    17941 cggcagcaat agataaaggc attaaaaaag acctttatga acagactttt cgtacctcgg
    18001 attattttgt ctatgatcca tttaatcctc gttctttaca aggatggcat ttagatgata
    18061 atcaaaagta ccagccgtta attcctaatg aacatggttg gctatggagt agacgtttag
    18121 gtttatggtt gggaacttgg gaaggaacgg tagaaaggga aactacaatt tgggcgcggt
    18181 tttatgatgt tgctggtaat ctagttttat taccagagga agcagctaaa tcgcaagcaa
    18241 aagcggctaa ggcacgagag gaggaggcta aggcaaaagc agataggttg gctgccagat
    18301 tacgagaatt gggtgaagat ccagatatct tgtaatcgtc aggtttccca aatccccgac
    18361 ttctgctgtc atcatctcta gaaattgcga tttgtcgtta gaagtcgggg atcttaattt
    18421 ttgcctgctc actcctgctg tataatcaac tggaagcact ggtataaaaa cggagagcaa
    18481 accgccaaaa ctgagtagaa ataaagaata agacaattgc taaaaatccc gcacctagcc
    18541 accaggtaaa ctgaatttga cctaacagag actgggctgg aactgtagtt aaaaaagtta
    18601 ctggaactat aaaggtaaag aagaagcgat aagccgccgg ataggctgta attggatatc
    18661 ttccagcatc tagaaaccct cttaatactt ctgtgacgtt gtatatttta acaaaccaaa
    18721 tacttgttgc gctgaggata aaccacaggc tgtaaagaat gactaaaccg caagccaagg
    18781 gaaaaatagt cagtaagtat ttgtcaattc ctaagttaag ttttctacca gcgtagccaa
    18841 tgatgagcaa acctaagatt aaatctggta ttccccagag ggaaagggta tgaatagata
    18901 accaaaactg actacgaata ggttttaata atacaaagtc taaggtccct tcttggacat
    18961 gacgcacaat ccgatttaag ttgggagcaa ggaaggtaga cgaaaagcct tgtaataggg
    19021 tgaaaattcc taagactact aaagctgcgt cccatgacca ccccgtaaaa gtgtagcctg
    19081 tgcggtaaaa taggaacaaa ccaaagatac tacctactaa attacctaag ctactgaaag
    19141 cagaaatgat aaaattaata cgatattcca tttctgccgc aatggcagca ttccaaaata
    19201 atctcaacac ttttaaatat cttgccattt ctcgccttta ccccaatatc tcttgaatat
    19261 aaaataattt tatctaaact taatcttatt tggtattttt ataatttatg aacgttaaaa
    19321 tgttgaatgc aacttcttaa gcaaatcgga ttttatgcac tttaatttac cggaattaat
    19381 taaatcgctg ggttattttg gagtatgggg aattatcttt gctgaatctg gtttattgat
    19441 tgggtttttt ctccctggtg atagtttact atttacggct ggatttgttg cttctcaaaa
    19501 cttgctaaat atttgggtac tgatttttgg tgcgtttttt tgtgctgtat taggtgataa
    19561 tgtcgggtat tttacagggc ataaatttgg cagaaaatta tttgagaagg atgattcttg
    19621 gttatttcgt aaaaaacata ttgtgaaaac tcaagatttt tatgaaaagc atgggaaaaa
    19681 aacaattgtc ttagctagat ttatgccaat tgtgaggact tttgcgccga ttgtagcagg
    19741 tattggggct atgcactatc ggtcttttat gtcttataac ttaattggtg gttttgtttg
    19801 gacatttggg attactttgt taggattttt cctgggaaaa actttgccag cggaacagtt
    19861 agataagtat cttttaccaa taattggctt aattgttgtt gtttctttat tcccatctgt
    19921 tattcatata attaaagaaa atagagctaa taaatgatca aatgctttgt tttgatgaca
    19981 gtttacccat ccctattccc aaatatgacc aaaagctggt agcgtcaaac aaaggaaaat
    20041 attttttgtg gatgtgacaa cttgaaaaca cgttctaatt attggcaact gttaccatat
    20101 atccgcaccc agtggcaacc tattgctaag ggttttgtag ggattttggg atatgtactg
    20161 gcaactttaa ccctgattaa tgtcgcgggt aagttggctg ttcccttcgg gaatggtaat
    20221 gtattagcga tcgctcaatt agccggaatc agtgctgcta tatttcttgt gcgcggcttt
    20281 tttcagtctg tacaagattt atacatggct aaggcagcgt taagaatcgc tttttatctc
    20341 cggcaacagg tttatactca tttacaaaaa ctcaatctca gctattttga aactgctaaa
    20401 gctggagatt tatcttatcg tctcacggaa gatgttgaca gggtgggaga agttattaat
    20461 aaactttttc atgattttac tccctgtgct ttacaattaa ttgctattcc catttacatg
    20521 atttatttga attggcaact taccttagca acggtaattg ttgccccaat tatgggaatt
    20581 ttaattggtt ggtttgggga acgtttacgg aaatattctc tcaaaagtca aagtcgtatt
    20641 tctgatttat cagctatttt aacggaagtt tttagcggga ttcgcttaat tcaagctttt
    20701 gctgcggaaa aatacgaaat tgatagattt agtcatgaag cagaacgcag ttttaaagct
    20761 aaatattcag tcgaaagatt aaaagcgatt caaattccca ttgtgggatt tttagaagct
    20821 gtgagtgcgt tatctttgtt aatggtagga acttggcaaa tatctcaacg taatttaact
    20881 gtcggtgaat tttttagtta tttaacagca gcagctttgt taattgatcc tattggtca
//
