LOCUS       NZ_JAAVIO010000001     23507 bp    DNA     linear   CON 03-AUG-2024
DEFINITION  Bacillus toyonensis strain M5 contig1, whole genome shotgun
            sequence.
ACCESSION   NZ_JAAVIO010000001
VERSION     NZ_JAAVIO010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus toyonensis
  ORGANISM  Bacillus toyonensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 1452061)
  AUTHORS   Huang,Y., Palmer,J.S., Ding,Y. and Yu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAR-2020) School of Food and Advanced Technology,
            Massey University, Private Bag 11222, Palmerston North,
            Manawatu-Wanganui 4442, New Zealand
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012395365.1-RS_2024_08_03
            Annotation Date                   :: 08/03/2024 02:52:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,219
            CDSs (total)                      :: 6,078
            Genes (coding)                    :: 5,835
            CDSs (with protein)               :: 5,835
            Genes (RNA)                       :: 141
            rRNAs                             :: 17, 6, 13 (5S, 16S, 23S)
            complete rRNAs                    :: 10 (5S)
            partial rRNAs                     :: 7, 6, 13 (5S, 16S, 23S)
            tRNAs                             :: 100
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 243
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 243
            Pseudo Genes (frameshifted)       :: 103 of 243
            Pseudo Genes (incomplete)         :: 148 of 243
            Pseudo Genes (internal stop)      :: 73 of 243
            Pseudo Genes (multiple problems)  :: 69 of 243
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:32:18
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1166316
            Orig. end                         :: 1189823
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAAVIO010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23507
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="3"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23507
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13507](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13507
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    493..509
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            complement(523..1068)
                     /locus_tag="HB668_RS05910"
                     /old_locus_tag="HB668_05905"
     CDS             complement(523..1068)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="HB668_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05905"
                     /product="hypothetical protein"
                     /protein_id="WP_001267648.1"
                     /transl_table=11
                     /translation="MRWRAGTFEKIETNHASIEQIINTYKKQNLNGGAVISCFKVHNEN
                     FFKEIPHGEDGHEHFFRRICNSLDIINNLEELKIHTSDKYKFRFKEHQAVMLDGSIAAQ
                     ILWGGAYEAFQERPVAAKQLAINVCQYMFQDRYEDIKVFESDHPWTDWFYDVVWDATWM
                     VLDSKEHKMWLICATDTD"
     gene            complement(1149..1418)
                     /locus_tag="HB668_RS05915"
                     /old_locus_tag="HB668_05910"
     CDS             complement(1149..1418)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195087.1"
                     /locus_tag="HB668_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05910"
                     /product="hypothetical protein"
                     /protein_id="WP_001193096.1"
                     /transl_table=11
                     /translation="MQTIASYPWSLRKIFVFFLCFILPPIGFIYILMNREALQKRDFIL
                     YVLFAAINISLWLSLMIFDRSMWMVAGHDVLSVIVIIVSNMNKG"
     gene            complement(1436..1798)
                     /locus_tag="HB668_RS05920"
                     /old_locus_tag="HB668_05915"
     CDS             complement(1436..1798)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034134.1"
                     /locus_tag="HB668_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05915"
                     /product="hypothetical protein"
                     /protein_id="WP_001034135.1"
                     /transl_table=11
                     /translation="MNKKAIFFLLTSLLLVASITYIICNTREQVPPILVWEDQEYYVTD
                     EPAQAEEVGQRLGEVTKKIEASKAPTKNSESNTLQEKTEVFTMIEEKKDDQSPLIIKEP
                     YGDEYRIVRPMLKQVL"
     gene            complement(1934..2116)
                     /locus_tag="HB668_RS05925"
                     /old_locus_tag="HB668_05920"
     CDS             complement(1934..2116)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="HB668_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05920"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178305.1"
                     /transl_table=11
                     /translation="MQMMYAFGMGIVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLITQSL"
     gene            complement(2145..2522)
                     /locus_tag="HB668_RS05930"
                     /old_locus_tag="HB668_05925"
     CDS             complement(2145..2522)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="HB668_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05925"
                     /product="hypothetical protein"
                     /protein_id="WP_001000064.1"
                     /transl_table=11
                     /translation="MNDSQKYFVIMGIIFLIMSGFMILAGIMTHSAPPSPTYTLLAMMI
                     MCFCLSYLHPQFKEKDERMKLIRYKGMFFSFFALTAYYLLFSIGLNLKVMTLSAVELLH
                     ILMALTMSTVFISFVVLAKRY"
     gene            complement(2519..2734)
                     /locus_tag="HB668_RS05935"
                     /old_locus_tag="HB668_05930"
     CDS             complement(2519..2734)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428504.1"
                     /locus_tag="HB668_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05930"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428507.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGEKG"
     gene            3702..6569
                     /gene="odhA"
                     /locus_tag="HB668_RS05940"
                     /old_locus_tag="HB668_05935"
     CDS             3702..6569
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="HB668_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05935"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_000197130.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPILDEIVLEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYTHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTSKSFVVLVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFIQEQLKSDYA
                     QVPPADTSDATIHVKVPDVVAKGIQPIDTGVELDSLRAMNEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGM
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIMKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDTVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVYSN"
     gene            6700..7959
                     /gene="odhB"
                     /locus_tag="HB668_RS05945"
                     /old_locus_tag="HB668_05940"
     CDS             6700..7959
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="HB668_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05940"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_000569924.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAPVAEQPKQETAEAPKA
                     AAPTAEQATALQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     aSDomain        8085..8384
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HB668_RS05950_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="4.20E-57"
                     /identifier="RREFam011.1"
                     /label="HB668_RS05950"
                     /locus_tag="HB668_RS05950"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.1"
                     /tool="antismash"
                     /translation="MNNLPAHAKLKANKDTFFLPDSNGGVYFRNNASSFRMDGDGIYNW
                     IEKLMPMFNGDHSLAEITDGLPLPYQHRVFEIGEILYENGFVRDVSQDAPHELNS"
     gene            8085..10004
                     /locus_tag="HB668_RS05950"
                     /old_locus_tag="HB668_05945"
     CDS             8085..10004
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="HB668_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05945"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_001061534.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1233.9,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     2.2e-55, bitscore: 181.1, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.6e-11,
                     bitscore: 39.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPAHAKLKANKDTFFLPDSNGGVYFRNNASSFRMDGDGIYNW
                     IEKLMPMFNGDHSLAEITDGLPLPYQHRVFEIGEILYENGFVRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFQTYRAANVLILGSGDMLTSLVSSLLESGLPTFHYLVTDY
                     METNYDRIHELVERAYEVDDNVLVQEIDTTIDRPLHEVFEPFDWILYVSQNGDIEGLRT
                     VHTICKEVGKNFIPAICLSTFGLAGPVVTADREECWESAWHRLHETTLQNENASAPFSP
                     ITGAMLANIIVFELFKHVADDSYREKEPQFFLLNCETLEGTWHPFIKHPLATDESFTID
                     TIENLTEKLAQRSNQHTSTELFRFFDSLTSKEAGIFHVWDEQNSYQLPLSQCNIQVATP
                     LSDGPASLLPLMTCAGLTHNEARREAGLTGIETYVAEIIHRLIPEHNDIGIGAGETMTE
                     GVYRALQQHLNNKLYERQSHMLEEITTIDLAEIHDTHCKFYYDALSTIHEAPKIAMSEE
                     ILSFPVVWVGVNDRWYGASSINMTLALRNALQLSLLHIQNEETPYRATVLPESSIILYD
                     TDSFRIEIQADEEIPDVQSLQLALQHLGEHNFYPFVFDLAIESFLKENLDGVYGVLIAK
                     EDGL"
     aSDomain        8115..8351
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HB668_RS05950_Thiopeptide_F_RRE.1"
                     /evalue="6.80E-13"
                     /identifier="RREFam004.1"
                     /label="HB668_RS05950"
                     /locus_tag="HB668_RS05950"
                     /protein_end="89"
                     /protein_start="10"
                     /score="39.4"
                     /tool="antismash"
                     /translation="KANKDTFFLPDSNGGVYFRNNASSFRMDGDGIYNWIEKLMPMFNG
                     DHSLAEITDGLPLPYQHRVFEIGEILYENGFVRD"
     gene            10001..11950
                     /locus_tag="HB668_RS05955"
                     /old_locus_tag="HB668_05950"
     CDS             10001..11950
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="HB668_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05950"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_000191878.1"
                     /sec_met_domain="YcaO (E-value: 3.5e-85, bitscore: 283.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1e-143, bitscore:
                     475.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQHILLIGDGLLADYVHDQLRKQYSIIRQHTITDELPENINLAL
                     VLHDGSPSTIHHDAELVFRSNHIPWLRAFTSFGEGVIGPYIHPLATGCTHCADGRRFIA
                     GFDQQEMWELQRKYALKSEHVTRRDVRATQNGILQMCQLIHAETEKILAHGHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPICSNLPTDTADAAQISLQPSLKTSAETYRCRSIHELN
                     TFLTRDYLDYRVGMLNGKMQHSLLPFADVIINMPLMFGNEGVAGRTHSFALSEATAILE
                     GLERYCGMSPRGKKTNVHGSFHDLEDHALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLSQNKPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLRTITGYELHVFNATMEHGIPSLWVIAK
                     NTRANGMNVVCAGGSHLDPIRAIKSAIHEIAGMLLIADDELEQKREYYEKCLQDPYLVN
                     KMEDHSMLYGLKETEERLHFLLRDDAPVQSFQEMNALQSFDMDLTSDLHQLLNRLHQSG
                     LEVIVVDQTVPLIEQNGLHCVKVMIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYRAEP
                     LTNEQLNPHPHPFP"
     gene            11966..13507
                     /locus_tag="HB668_RS05960"
                     /old_locus_tag="HB668_05955"
     CDS             11966..13507
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108035.1"
                     /locus_tag="HB668_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05955"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_168387441.1"
                     /sec_met_domain="PF00881 (E-value: 1.9e-09, bitscore: 34.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLDTFLHHLHFTIDEIMPNHEVDWEDAPLPYKLYRNVPVIPLSS
                     EIPISLPNSSTTPTLDEIGAYLLYSFGITQLCQLNSERNLFRRSIPSGGALYPNELYIY
                     LKLNHYPDGIYHYDAAHHRLILLREGNFDSYLIDTLGNRCNIHSCFGAAFVSTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLECAKQFGYKNGIYFQFLDRAINHLLGLTEGEESVYA
                     VIPLSTEPNIDWFHDDYRKNKTVTSHDLLQQIPPLAHEHFIRSKHVEGYPMITKINEAS
                     MIESTEHFQTLAHEEYYQHHAHTVQLPKVERLSYNFLQLCKERYSPNDDFTLTKWDAAE
                     LATLLQEASLSLPYYNDLDGKYINENARVSLYGCFYNVKTIENGAYAYNSKTHSIHPIR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTRALGYRGYRIHQMEAGILVHKLV
                     FAATAMGMGGHPLLSFDTNSCDQLYGIDGGNETSLIQIPVGAYRVRNWLKGSLHN"
     gene            13599..14189
                     /locus_tag="HB668_RS05965"
                     /old_locus_tag="HB668_05960"
     CDS             13599..14189
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-149). E-value: 3.9e-08. Score:
                     23.7. Matches aSDomain: nrpspksdomains_HB668_RS05965_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158829.1"
                     /locus_tag="HB668_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05960"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_000025730.1"
                     /transl_table=11
                     /translation="MSILQQLIQQAKNPRGTIGSSMLCIMNAAHTKLTKWALQKVHIKT
                     EAVILDIGCGGGKTIHTLSKRTTFGKIYGIDYSDQAVENSKKANMKDVKTGKVIIHQAN
                     VSSIPYNTNFFDLITAFQTHYFWPDVEHDIKEVLRVLQPNGSFLLVAETFKIQYHMKKF
                     KTTEELINLFYKTGFKSVKCYEERGCICVIGNK"
     aSDomain        13743..14045
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HB668_RS05965_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.90E-08"
                     /label="HB668_RS05965_oMT.1"
                     /locus_tag="HB668_RS05965"
                     /protein_end="149"
                     /protein_start="48"
                     /score="23.7"
                     /tool="antismash"
                     /translation="ILDIGCGGGKTIHTLSKRTTFGKIYGIDYSDQAVENSKKANMKDV
                     KTGKVIIHQANVSSIPYNTNFFDLITAFQTHYFWPDVEHDIKEVLRVLQPNGSFLL"
     gene            complement(14221..14631)
                     /locus_tag="HB668_RS05970"
                     /old_locus_tag="HB668_05965"
     CDS             complement(14221..14631)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="HB668_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05965"
                     /product="DUF3908 family protein"
                     /protein_id="WP_000996796.1"
                     /transl_table=11
                     /translation="MAINMKTIEEWIAESNARQEEDFGHVVEEMKEVCVGLDNATLIYT
                     KNVFCFGKKVEVLFFFQDHVVIGQEKDEYVEIEKLKYDAITNSNLKTNDKNTTLELKFA
                     NGQTINLDSLNDNYGTKNWLFARQIKSIFKVI"
     misc_feature    complement(14759..14773)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            complement(14882..15371)
                     /locus_tag="HB668_RS05975"
                     /old_locus_tag="HB668_05970"
                     /pseudo=""
     CDS             complement(14882..15371)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135035.1"
                     /locus_tag="HB668_RS05975"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05970"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVVALQRVQESEKEILRNLYALYLHDLSKFTTNITIGVNGFFGI"
     gene            complement(15448..16782)
                     /locus_tag="HB668_RS05980"
                     /old_locus_tag="HB668_05975"
     CDS             complement(15448..16782)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="HB668_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05975"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_001110250.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.2e-63, bitscore:
                     209.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDETANVVTLEKGEIYSYAQCGLP
                     YVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAKHTETKDVFEFT
                     YDRLLIATGVRPVMPEWEGRELQGIHLLKTIPDTERILKTLETNKVEDVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHHIEIVTNENVKAFRGKER
                     VEEIETDKGTYKADLVLVSVGVKPNTDFLEGTNIRTNYKGAIEVNAYMQTNVQDVYAAG
                     DCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMVDKRRSFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            16982..17404
                     /locus_tag="HB668_RS05985"
                     /old_locus_tag="HB668_05980"
     CDS             16982..17404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336278.1"
                     /locus_tag="HB668_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05980"
                     /product="hypothetical protein"
                     /protein_id="WP_000336278.1"
                     /transl_table=11
                     /translation="MCPGLLAQTPDEPQEPKAATPLDQEFSINATIYSARAWLSDNDTY
                     AQDIWKGTRFASASHAGKSIFPSGTIKVINLSADTITVTTSGDSDHNLKTVVAPYSEVA
                     LSPSSLSAVQASTSGKASKVTFLFHIFFSRDPGPAK"
     gene            complement(17451..18686)
                     /locus_tag="HB668_RS05990"
                     /old_locus_tag="HB668_05985"
     CDS             complement(17451..18686)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="HB668_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05985"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_001099924.1"
                     /transl_table=11
                     /translation="MNVCTKCGTQFVDGVQFCQNCGTKREIPVVKKKMGSGTKIGITFL
                     ALLVIAIVGLYLYGSSYYTQVAQVDRMITILQERDGEKLAEIITTDDPSVIVTRESFKP
                     LFSYIKENPSYVNELKQYLKQGEKQGDGIERADFSLTKDGKHYFIFDRYKLKARTYYTT
                     LLSNEKGASLKMNGKEIDKTEDKNFQKQYGPFLPGAQVFQVEYKNDYVKLSREEKVVLM
                     KQSQNNVTIDLTLQGQYITVQTNAPGATLYVNQKPVTALTGEEITWGPVATDGSATIYL
                     ERNGESGRETTKVETVTALSAYNLPFEKKSVEKTVVYNVTPPPTTGYVYNGFIFPDSDI
                     RKLTNADLTYVTKEQLKIARNEIYARHGNIFQTKDMQAYFSKQSWYRENPYFTGKLTDI
                     EAYNVELIKSRE"
     gene            complement(18706..19491)
                     /locus_tag="HB668_RS05995"
                     /old_locus_tag="HB668_05990"
     CDS             complement(18706..19491)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650096.1"
                     /locus_tag="HB668_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05990"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_000650065.1"
                     /transl_table=11
                     /translation="MKCPACHTENAVEAKFCGNCGHSLTEEVVASGVQEENQQSSHAEQ
                     AKETRPNETVEQAKRFTSGYFRFFKQAFQAPTAIMQSGNVEVRNGIVSLVLICFLGACI
                     FYRMMSAGAAVTRTLVPEVYTPTFFGESVTVFFFLLILTLFVGFIIFISGKMMKSSFSF
                     LEVFGIWGTIATPVIAILVLTFLFSFLLIFFLPILLSLATTYIGISIIVAILKLDNGGL
                     DLVYTLLIANVFIGIVTFIVLWSYISTVIQAFTQGLTGF"
     gene            19693..20526
                     /locus_tag="HB668_RS06000"
                     /old_locus_tag="HB668_05995"
     CDS             19693..20526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397498.1"
                     /locus_tag="HB668_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_05995"
                     /product="hypothetical protein"
                     /protein_id="WP_168387442.1"
                     /transl_table=11
                     /translation="MEFVNSIFQILLTSVIQLFSLIGVIIVIGFLLGYLESLTRMYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCVLFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     VYQRIGNFFIGIGPIISGITALILFMRYFVPESYFVFNTTLEKTIASTSITLEMVQNML
                     LSTFVLLKSLFTINNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAELFQYDSNQLIGKVMKYNMYLIAFSSVALLFSCISTLVSFGFYKIRGGRSL"
     gene            complement(20553..20678)
                     /locus_tag="HB668_RS31670"
                     /old_locus_tag="HB668_06000"
     CDS             complement(20553..20678)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024729.4"
                     /locus_tag="HB668_RS31670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_06000"
                     /product="IS3 family transposase"
                     /protein_id="WP_353763590.1"
                     /transl_table=11
                     /translation="MINRFDEVKVAVRKYMHLYNYQRFQKKLNNLSPYKYRTQVA"
     gene            complement(20730..22367)
                     /locus_tag="HB668_RS06010"
                     /old_locus_tag="HB668_06005"
     CDS             complement(20730..22367)
                     /GO_function="GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472903.1"
                     /locus_tag="HB668_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_06005"
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="WP_000472905.1"
                     /transl_table=11
                     /translation="MFKKAAAIVLTSSIISIPITGLAETVTTSNTATVNVNAVKQSGWV
                     QQNGKWYYFNPDGTIKKGWLLDNNKWYYLNSSGIMQTGWLFDQGVWYYLNASGAMQTGW
                     LLDQGVWYYLNSNGSMKTGWLLDQGVWYYLNASGAMQTGWLLNQGVWYYLNSNGSMKTG
                     WLLDNNKWYYLNSSGGMKIGWLQDGNNRYYLQNDGSMKIGWLQVNNTWYYLNASGAMQT
                     SWSFIDGSWYYLQNNGAMKTDWLQDGDTWYYLQSNGMMQTGTASINGTTYHFDKSGAWT
                     PENNITATTYLDLDLTYASNVTGAEIDANIKKYHPDSPLIGHGNDFVEAQAKHGVNALY
                     LAAHAILESGYGKSEIAYRKHNLFGLRAYDADPFKYAKYLPTFGDSISYNANYVREKYL
                     EANGSYFNGPTLKGMNVMYSTDQEWSAKIVKIMERIKPFQKKDYVYAKKLPKNPNSLNV
                     DALSSDIPYKTYSQGTTKTVKLATSYYVVPYPFDGTIKSQSVTKNDQGTLATGTPVFIY
                     REDPNGWIEFSLTMNGNKYWVLKAGLNM"
     gene            complement(22859..23278)
                     /locus_tag="HB668_RS06015"
                     /old_locus_tag="HB668_06010"
     CDS             complement(22859..23278)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084723.1"
                     /locus_tag="HB668_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HB668_06010"
                     /product="hypothetical protein"
                     /protein_id="WP_001084723.1"
                     /transl_table=11
                     /translation="MNSINIQSILDDLWGATILETHIDLLNDNIKFTLQVIDNGVIKDY
                     KLVLIEVSSFYYVKDDEKRRFAFYDREKVDYLELTTIYYEDPNLSEVKLSLQNEKEWSS
                     KYSTGVNIIIEIWDSILLVEAKQFSLNGKVINLKM"
ORIGIN
        1 tggcataact tctcccattg ctttcgttac ggcaacagat agatcagcag atgtaatttt
       61 cactttcact tctgctttat catctgtttt tgatacttct tctagttttt caaatttaaa
      121 gtttttcgta attgcgctta gcatttcttt tgcttcagca tcatctgttt tttcatttag
      181 tttattaaat tccttgtcac tttcaacgaa tgtacgagcc ttctctacat cccctttttg
      241 tattgctgtt aaaaattctt cagcagtatc tttcgggttt gcacatcctg ctagaacacc
      301 aactgttaac cctattacca tcattagtag caataatttc tttacctttt tcacgttcat
      361 tctcctctta ccttaccttt tcttttctag taagccatca ctatacaaca gtataaaact
      421 tacattacaa acatttttta gtataacatt tatacgattt attttctatt ctttcccaaa
      481 agataaagag ccttgtagca tttctacaag actctttatc ttttaatccg tatccgtagc
      541 acaaattaac cacattttat gctccttact atctaatacc atccaagtag catcccatac
      601 aacatcgtaa aaccaatctg tccaagggtg gtcactttca aacactttaa tatcttcgta
      661 tcgatcttgg aacatatatt ggcatacatt aatcgctaat tgcttcgcag caaccggccg
      721 ttcttgaaat gcttcatacg ctccgcccca caaaatttga gcggcaatgc taccatcaag
      781 catgactgcc tgatgctctt taaaacgaaa cttatattta tctgatgtat gtatttttaa
      841 ttcttctaag ttattgatta tatctaaaga gttgcagatt cttctgaaaa agtgctcgtg
      901 tccatcttct ccatgtggta tttctttgaa aaagttttcg ttatgtactt taaaacagct
      961 tataaccgct ccaccattta agttttgttt cttatatgta tttataattt gttcaataga
     1021 tgcatggttt gtttctattt tttcaaacgt tcctgctctc catctcataa tgccactact
     1081 ctctattaaa gatttgttat ttcattataa atatcaaaat aaaacccagc aactttaaaa
     1141 ttgctgggtt atcccttatt catattcgaa acaataataa caattacgct aagcacatca
     1201 tgccccgcta ccatccacat actcctatca aaaatcatca atgataacca aagcgatata
     1261 ttaatagcag caaataatac atataaaatg aaatctctct tttgtagtgc ttctctattc
     1321 atcaaaatat aaatgaaacc gataggaggc agaataaagc aaaggaaaaa gacaaatatt
     1381 tttcttaacg accacggata tgaagctatt gtctgcatat gagtctcctt ttctattata
     1441 gtacttgctt taacatcggc cttactattc tatattcatc accataaggt tcctttatga
     1501 ttaaaggcga ttgatcatct tttttttctt caatcattgt gaatacttct gttttttctt
     1561 gtaatgtatt agattcacta tttttagtag gtgctttact tgcttcaatt ttctttgtca
     1621 cttctccgag cctttgcccg acttcttctg cttgagcagg ttcatccgta acgtagtatt
     1681 cttggtcctc ccatactaat ataggtggta cttgttctcg tgtgttacat attatataag
     1741 taatactagc tacaagtagt agacttgtta ataaaaagaa gatagctttt ttattcatat
     1801 actattctcc ttttctatta ttttattgga ttatacaata tagcttccat gtagtaaatg
     1861 gtttttgtgg taatttttag gtttttatac aaaaagaaaa accttacaaa aagtaaggtt
     1921 tcatttttaa aatttataat gattgagtaa ttaatacaat cattacgatg atcgctataa
     1981 acataacaac taaacagcca atcattttat aaaatcctcg tttcgttaac gtcccgcctt
     2041 gaacgtcttt acgaatgaat aggaacaccg ctaaaaataa aacgatcccc ataccaaaag
     2101 catacatcat ttgcatatgt taatcttcct ttctctcttc catcttaata tctttttgcc
     2161 aaaacaacaa atgagataaa gacggtactc attgtaagtg ccataagtat atgtaatagt
     2221 tcaaccgcag atagtgtcat tacttttaaa tttaagccga tagagaaaag gagataatac
     2281 gctgttaatg caaaaaaact gaagaacatc cctttataac gaatgagttt cattcgctca
     2341 tctttttctt taaattgcgg gtgtaagtaa cttaagcaga aacacataat catcattgct
     2401 agtaacgtat aagtaggact tggtggtgct gaatgtgtca ttatacctgc tagtatcata
     2461 aatccactca taattaaaaa gataattccc ataataacaa aatacttttg tgaatcattc
     2521 atcctttctc cccctcttct tttccttcat aaataaatac atgttctatc gttgtttgaa
     2581 atgttttcgc tatttcaaat gctaatggaa gtgatggatc atatttccct ttttcaattg
     2641 aaatgatggt ttgtctggaa actccaagtt tctcagccaa tttttcttga gatagtccaa
     2701 atttttttcg atattcgacc attttatttt ccaaggaaat ttctccctcc tcccttatat
     2761 cgagtatata tgtaaagtaa actttacgtc aagtttcctt tacatatatt tcagtttgtt
     2821 tcacgctatt tatcccgcat taacaggcag taagactccc acctcaaaat tcagtgaata
     2881 cgaggaattt aggtgggaaa taactgcccg attggtgaag gctaataatc agtggtggat
     2941 ggacaaaccc cacactgatt aaagtttcac tttattatag aagaaacttt ttcaatttca
     3001 gcacgtctat tttgtaatgc aacatggaac aatgtatata tccgttacta tatcccttct
     3061 ccatttttat aaaaatttaa tatctccata tttgttttat ccttttaaaa tatttcattt
     3121 gccgctttat tagatgaaat gcgttatttg ttttacggta tttttcggca tattaataga
     3181 aactaacggt ttatgaagca ttttttatgt ttagccactt tttttgtaga aatccttcgt
     3241 tttcctttca atatttaaca ctaccgaaat aaagtttact ctaaattcat aatcttttat
     3301 tttttatact atattccgtt atattgttgt ataatatcaa tgaaagcgct tattatttca
     3361 atatacataa ttcgaacttt attttatcga aacattctaa ctattatacc tatatgtaaa
     3421 tgcaacaatt atagttgtta gtgtaggtat accaaatata tccactccat ttttctgtaa
     3481 aattacttta taacatgaaa gattaacttg ggtgataagt tattgtgaat gtttttttac
     3541 aaaacagata agtaatagtg tttggtatta tgtaaattat tgtaataaca taagagtaaa
     3601 gacaacattt acattaatta ttagttcatc aattattgaa aaagagcaaa atgcaccttt
     3661 tgtataggaa aaggattata tgcattggga ggtttaaaca aatgacgagg aagaatacaa
     3721 cgacaaaccc ttgggccaag ttccatggtc cgaaccttgg ttatgttatt gaacagtatg
     3781 atctttacgt aactggagca ggttctgttg atccggaatt acaagagctt tttgaaattt
     3841 ttggagctcc ttcgtttcaa gatgatgtcg taacagggga caacacagca acacattttt
     3901 ctcctcaaaa cacaggtaac attgaaaaaa ttcttaaagt cgttcaactc gttgaacaga
     3961 ttcgttcttt cgggcatacg ttggctcaca tcaacccgat ggaagatgct gcaaacggac
     4021 aatctcttct tgagaaagca atgaacgaat tgagcgatgc tgacttgaaa gcgattccag
     4081 ctaaaacagt atggcaagat gcaccagagg gtattcacac tgcacttgat gtaattcata
     4141 gattaaaaga cgtttataca aaatctttag cttatgaatt ctcacatata caagatagtg
     4201 aagaacgcgc gtggttgcat caaatggtgg aatcaaattc attgcgtcaa ccattatcaa
     4261 ataaaaaacg aactgctctt ttaaaacgtt taacagctgt tgaaggtttc gagcaattct
     4321 tgcataaaac attcgttggg caaaagcgtt tctctatcga gggcgttgat atgcttgtac
     4381 caattctaga tgaaattgtg ctagaaggtg ctaaaggcgg cgttgaagat gtcatgattg
     4441 gtatggctca ccgcggtcgt ctaagcgtac ttgctcacgt attagaaaaa ccatatactc
     4501 acatgtttgc tgaattcaaa catgcaaaaa tagaaggcgc agtggcaaat gctggctgga
     4561 ctggcgacgt gaaataccat ttaggtagag aacaagtcgt tgggaatgaa gaagttagca
     4621 ctcgcgttac attagcaaat aacccgagtc accttgagtt cgttaatcct gttgtggaag
     4681 gtttcgcacg tgcggctcaa gaaaatcgta aaaagtctgg tcttccagaa caagatactt
     4741 ctaaatcatt cgtagtttta gttcatggtg acgctgcatt ccctggtcaa ggtattgtat
     4801 ctgagacact aaacttaagc agattgaacg cgtatcaaac gggcggaaca attcatgtta
     4861 tcgcaaacaa tgcagttggt tttacgactg atagctatga ttctcgttct acgaaatatt
     4921 caagcgacct tgcaaaaggt tttgatattc cgattgttca cgtgaacgct gatgatccag
     4981 aagcttgcct tgctgctgct aacctggcga ttcaatatcg tacgttgttc aaaaaagact
     5041 tcttaatcga tttaattggt taccgtcgct acggtcataa cgaaatggat gacccagcag
     5101 ttacgcaacc acaagtgtac aaaaaaatta aaaatcaccc aactgtaaga gcaatttatg
     5161 cagatcaatt acaagctgct ggtgttctaa atgcagatga ggttgaaaca attactcaat
     5221 ttatacaaga acaattaaaa tctgattatg cacaagtacc accagctgat acgagcgatg
     5281 caacaattca cgttaaagta ccagatgttg ttgcaaaagg cattcagcca attgatactg
     5341 gtgttgaact tgactcactt cgtgcaatga atgaaggtct attatcttgg ccagaaggct
     5401 ttaacgtata tccgaaggtg aagaaaattc ttgaacgccg taaagatgct cttgaagaga
     5461 acggtaaaat tgaatgggca cttgctgagt cattagcatt cgcttctatt ttacaagaag
     5521 gtacaccaat tcgtttaact ggtcaagatt cacagcgtgg tacattcgcg catcgtcaca
     5581 tcgtattaca cgatactgat acaaatgaaa catattcacc attacatcgc ttaccaaaca
     5641 ttaacgcttc attctctgtt cataacagtc cgttatcaga agctgctgtt gttggttacg
     5701 agtatggtta taacgtattt gctccagaaa ctcttgttat gtgggaagcg caatatggtg
     5761 acttctcaaa tactgcgcaa gcattatttg atcaatacgt ttcagctgga agagcaaaat
     5821 ggggtcaaaa atctggttta gttcttctat taccacacgg ttatgaaggt caaggaccag
     5881 agcattctag tgcacgtcca gagcgtttct tacagttagc tgctgaaaac aactggacag
     5941 ttgcaaactt aacgagcgca gcacagtact tccatatctt gcgtcgtcaa gcatctattt
     6001 taggaacaga agctgttcga cctttagtac ttatgacgcc gaagagttta ttacgtcacc
     6061 cacttacgct ttcaactgct agtcagttaa gcgaaggacg tttccaacct gctttagaac
     6121 aagaaaacct tggcatgaaa ccaaataaag ttaaacgtct tgttttaagt acaggtaaaa
     6181 tggcgattga cttagcagcg gaaatcgagt ctggtaaaca tgaatacaac ttagatgaag
     6241 ttcatgtcgt tcgcattgaa cagttgtatc cattccctgc tgaaaaagtt caatctatta
     6301 tgaaacgctt taaaaactta gaagaaatta tttgggttca agaagaacct cgtaatatgg
     6361 gtgcatggca ttacatggct ccaattctgt tcgaactagc tggagataca gtgaaaacag
     6421 gttacattgg acgcccagat cgttctagcc catctggtgg cgatccgttc gctcacaaag
     6481 ctgagcaaga actaattgtg gcgcacgctt tagatgtgaa gtataacttc cgtcaagata
     6541 aacaagaaat tgaagtttat agcaactaaa agtaacaatg aatttttccc ggctcgactt
     6601 gggcagatat tctgcccaag tcgagctaac aaatggagat taccgaagat taaagaagac
     6661 aaaacacacc gttaggcaaa taaggggagg acatttaaaa tgatcgaaat taaagtacct
     6721 gagcttgcag aatctattac agaaggaact atttcacaat ggcttatcaa cgtaggtgac
     6781 aaagttgaga aaggtggcag cgttgttgag cttgaaactg ataaagtcaa tgtagaaatc
     6841 attgcagaag attcaggtat tgtatcaaag ttactaggcg agcctgggga tacagttgaa
     6901 gttggcgcaa ctatcgcaat tttagatgca aatggcgcac cagtggcagt aagtacacct
     6961 gcaccagtgg ctgagcaacc aaaacaagaa acagctgaag caccgaaagc tgctgctcca
     7021 actgctgaac aagctacggc tctacaaggt ttaccaaata cgaaccgtcc tatcgcatca
     7081 ccagctgcta gaaaaatggc tcgtgaatta ggaatcgact taaacgacgt acgtagcaca
     7141 gatccacttg gacgtgtgag accacatgat gtacaagctc atgctgcagc accaaaagaa
     7201 gcaccagctg ctccaaaaag tccagctcct gctccagttg caaaaacgga atttgaaaaa
     7261 ccagttgagc gcgtaaaaat gtcccgccgc cgtcaaacaa ttgcaaaacg tcttgtagaa
     7321 gtacaacaaa catctgcaat gttaacaaca tttaacgaag ttgatatgag tgcaatcatg
     7381 gaattacgta aagagcgtaa agatgctttc gagaaaaaac atgatgtacg tcttggcttt
     7441 atgtcattct tcacaaaagc agttgttgca gcattaaaac aattcccatt attaaatgct
     7501 gaaattcaag gcgacgagct tatcattaaa aaattctatg atatcggtat tgcagtagca
     7561 gctccagatg gattagttgt tccagttgta cgcgatgcta accaattaaa cttcgctgaa
     7621 atcgaaagcg aaattcgtaa tttaggtatg aaagcacgtg ataataaact ttcattaaaa
     7681 gagctacaag gtggtacatt tacaattaca aacggtggtg tattcggttc tctaatgtca
     7741 acaccaatcc taaacagccc acaagtaggt attttaggaa tgcacaaaat ccaagtaaga
     7801 cccgttgcaa ttgatgcaga acgtatggaa aatcgtccga tgatgtacct tgcactatct
     7861 tacgatcacc gtattgttga tggtaaagaa gcagttagct tccttgttgc tgttaaagat
     7921 atgcttgaag atccaaaatc attattatta gaaggttgat agactaatag tctattagag
     7981 gctgtagaat aaatcattct acagcctttt tttattgcgt tcatacggga caaatttcat
     8041 gacataagct aataatgtat gcttaaaacg taaggaggat taaaatgaat aaccttccag
     8101 ctcatgcaaa gcttaaagca aataaggata ctttcttcct tcccgactca aacgggggtg
     8161 tctattttcg aaataacgcc agttcattcc gcatggacgg tgatggaatt tataactgga
     8221 ttgaaaaatt aatgcctatg tttaatggtg atcattcttt agcagaaata accgatggtc
     8281 ttcctctccc ctatcaacat cgtgtatttg aaattggaga gattttatat gaaaatggtt
     8341 ttgttcgtga tgtaagtcaa gatgcacctc atgaattaaa cagtgcatta ctcgataggt
     8401 atgcttcgca aattgaattt ctagaagctg attctcattc aggtgcttta aaattccaga
     8461 cgtaccgcgc agcaaatgtc cttatacttg gttctgggga tatgcttact tccttagttt
     8521 cttctttact agaatccgga ttacctacat ttcattacct tgtcacagat tatatggaaa
     8581 caaattacga ccgaattcat gaactagtag aacgtgcata tgaagttgat gacaatgtac
     8641 ttgttcaaga aatagatact acaattgacc gccccctgca tgaagtgttc gaaccctttg
     8701 actggatttt atacgtttct caaaatggag acattgaagg cttaagaaca gttcacacga
     8761 tttgcaagga agtaggaaag aacttcatac ccgccatttg tttatcaaca ttcggtttgg
     8821 ctggtcctgt cgtaacagct gatcgtgaag aatgctggga atcagcttgg catcggctac
     8881 atgaaactac tttgcaaaat gaaaatgcat cagctccttt ttcaccaatt actggcgcaa
     8941 tgttagcaaa tataattgtt tttgaattat ttaaacacgt cgctgatgat tcatatcgag
     9001 aaaaagagcc acaattcttt ttattaaact gtgaaacact cgaagggaca tggcatcctt
     9061 ttataaaaca tcctctcgca actgatgaaa gttttacaat tgatacaata gaaaatctta
     9121 ccgaaaaact tgcgcagcgg tccaaccaac atacttcaac tgaattgttc cgttttttcg
     9181 actcattaac ttctaaagaa gctggtatat tccatgtgtg ggatgaacaa aattcatatc
     9241 aactaccgtt atcacaatgc aatattcaag tagctacacc actatccgat ggtcccgctt
     9301 ccctcctgcc tcttatgact tgcgctggtt tgactcataa tgaagctcgc cgtgaagctg
     9361 gtttaacagg aattgaaaca tatgtagctg aaatcattca tcgccttatt cctgaacata
     9421 acgatatcgg tattggtgct ggggaaacga tgacagaagg tgtataccgg gcactacaac
     9481 aacatttaaa caataaacta tatgagcggc aatcacatat gctagaagaa attacaacga
     9541 tcgacctagc tgaaattcat gatacacatt gtaagtttta ttacgatgct ctctctacaa
     9601 ttcatgaagc acctaaaata gcaatgagtg aagagattct tagttttcca gtcgtttggg
     9661 tcggtgtaaa tgatagatgg tatggcgcat ccagtattaa tatgacgtta gcgttacgta
     9721 acgcactaca actatctctt cttcacattc aaaatgaaga aactccatac agagctactg
     9781 ttttgcctga atcatctatt attttatatg acactgattc ttttcgaata gaaatacaag
     9841 cggacgaaga aattccagat gtgcaatctt tacagcttgc cttgcagcat ttaggagaac
     9901 ataattttta tccattcgtg tttgatttag cgattgaatc atttttgaaa gaaaatttag
     9961 atggtgtgta cggggtatta attgcaaagg aggacggtct atgactcaac atatattgct
    10021 tataggagat ggcctacttg cagactatgt acatgatcaa ttacgcaaac aatattccat
    10081 cattcgccaa catacaatta cagacgaact ccctgaaaat atcaacctcg ctctcgtatt
    10141 acatgacggc tctccttcta ctattcatca tgatgctgag cttgtttttc gttccaatca
    10201 tattccgtgg ctacgtgcgt ttacttcatt tggtgaaggt gttatcggac cttatattca
    10261 tcctcttgca acgggatgca cccattgtgc cgatggacga cgctttatcg ccggatttga
    10321 tcaacaagaa atgtgggaat tacagcggaa atatgcattg aaatcagagc acgtaacgag
    10381 gcgtgatgta cgcgccaccc aaaatggcat tctgcaaatg tgccagctca ttcatgctga
    10441 aacggagaaa atattagctc acggacattc ttctttagaa aatgaactca ttttactaaa
    10501 cttacaaaca ctgcaatgta cgcggcattc ttttcttcca gatcctctct gtcctatatg
    10561 tagtaattta cctactgata ctgcggatgc ggcacagatt tctttacaac cgagcttaaa
    10621 aacaagtgct gaaacgtatc gctgtcgttc tattcatgaa ctaaatacat ttttaacgag
    10681 agactattta gattaccggg ttggtatgtt gaatggaaaa atgcagcatt ctttattacc
    10741 attcgctgac gtcattataa acatgccgtt aatgtttggg aatgaaggtg ttgcaggtcg
    10801 aacccattca tttgcactga gtgaagcaac tgctatttta gaaggtttag aacgatattg
    10861 tggtatgtca cctcgaggaa aaaagacaaa tgtgcatggt agttttcatg atttagagga
    10921 tcatgcactg aatcccctca cactcggtgt acatacaaat gaacattata atcgtgatag
    10981 ttttccgttt aagccgtttg atcctgacta tgaacaaaac tgggtatggg gctattcttt
    11041 atcacaaaac aagccacttt tagttccaga atcaatcgct tattatagcc tcggtcatcg
    11101 ggatgctttc gtgtatgaaa catccaatgg ttgtgcaatt ggtggtagtt tagaagaagc
    11161 aatttttcac ggcattttag aaattgtaga gcgtgatgcc ttcttgctca cttggtatgc
    11221 tgaattacct cttccccgcc ttgatcttag ctcagcaaac gatacggaat tacaattaat
    11281 gattcagcgg ttacgcacga ttaccgggta tgaattacac gtttttaacg cgacgatgga
    11341 acatggcatc ccgagtttat gggtaattgc gaaaaatacg cgtgcaaatg gaatgaacgt
    11401 tgtttgtgca gggggctctc atttagatcc tattcgagct ataaaaagtg caattcacga
    11461 aatagcaggc atgttactaa tagcagatga tgagctcgag caaaaaagag agtactacga
    11521 aaaatgctta caagatcctt atctcgttaa taaaatggaa gaccatagta tgctgtacgg
    11581 attaaaagaa acggaagaac gtcttcattt ccttttacgt gacgatgctc cggtgcaatc
    11641 gttccaagaa atgaatgcat tacaatcgtt tgatatggat ttgacatctg atcttcatca
    11701 acttttaaat cgtttgcatc aatctgggct cgaagtaatc gttgtagatc aaaccgtccc
    11761 ccttatagag cagaacggat tacattgtgt aaaagtcatg atcccaggca tgctaccgat
    11821 gacgttcggt caccatctca ctcgtgttac cggactggat agagtgtaca ccgtaccgat
    11881 gacacttgga tatagggctg agcctttaac aaacgaacaa ttaaatccac atcctcatcc
    11941 atttccatag taaagggggg atttcatgca gctagatact tttttacatc atctccattt
    12001 cactattgat gaaattatgc cgaatcatga ggtggactgg gaagacgcac cgcttcctta
    12061 taagttatat cgaaatgtac ctgtcatccc tctctcttca gaaatcccaa tatctttgcc
    12121 gaactcttct actacaccta ctttggatga gattggtgct taccttttgt attcatttgg
    12181 tataacccaa ttatgtcagc tcaatagcga aagaaattta ttccggaggt ctatcccttc
    12241 aggtggtgct ttatatccga atgaattgta tatatattta aaattgaatc attatccaga
    12301 cggcatttac cattatgacg ctgcgcatca ccgacttatc ttacttcgcg aaggaaattt
    12361 tgattcttat cttatagaca cactcggcaa tcgctgtaac atacattctt gctttggtgc
    12421 tgcatttgta tccactatgt tttggaaaaa cttttttaaa tacaataact tttcgtatcg
    12481 tctgcaagga ttagatagcg gcgttctcat cggtcaatta ctcgaatgtg cgaaacagtt
    12541 cggttacaaa aatggcatat actttcaatt tctagaccgt gcaatcaatc atttactcgg
    12601 actgaccgaa ggagaagaaa gtgtgtatgc tgttattcct ttaagtacag aaccgaatat
    12661 agattggttc cacgatgatt atcgtaaaaa taaaaccgtt acttctcatg acttattgca
    12721 gcaaattcca cctttagcac atgagcattt cattcgttcc aaacatgtgg aaggatatcc
    12781 aatgataaca aaaataaatg aagcatctat gattgaatcg acagaacact tccaaacact
    12841 agctcatgaa gagtactatc aacatcatgc gcacactgta cagctaccga aagtagagcg
    12901 tttatcgtat aatttcttac aactttgtaa agaacggtac tcccctaacg atgactttac
    12961 tttaacgaaa tgggatgcag ctgagctcgc tactttacta caagaagcga gtctctccct
    13021 cccctattac aacgaccttg atggcaagta tataaatgaa aatgcacgcg tctccttata
    13081 tggatgtttt tataacgtaa aaactattga aaacggggct tatgcttata acagtaaaac
    13141 acattccata cacccaattc ggtatggaga ccttcgttac ccccttcagt ctagtatgac
    13201 gatggataac gtaaaccttt ttcaagtacc actttgctta catgtagttg gaaagaagga
    13261 ttactacaca cgtgcattag gctatagagg atatcgcatt caccaaatgg aagctggtat
    13321 actcgttcat aaactcgttt tcgctgcgac cgctatgggg atgggtggtc atccgttact
    13381 aagttttgat acaaattctt gtgatcaatt gtacgggatt gatggtggaa atgaaacatc
    13441 acttattcaa attcctgttg gggcgtatcg agtgcggaat tggttaaaag gttctttgca
    13501 taattaaaag cacgccgtcc accggcgtgc ttttttaaag gacttaattt ataaaaagcg
    13561 aaataagtat atattcttac ataaaaggag agtctgattt gagcatttta caacaattaa
    13621 ttcagcaagc aaaaaatcct cgtggaacaa ttggttcttc catgctttgt attatgaacg
    13681 ctgcacatac gaaattaaca aagtgggcgt tgcaaaaagt gcatataaag acagaggcag
    13741 ttatattaga tatcggctgt ggcggaggca aaacaataca cactctttca aaaagaacta
    13801 catttgggaa aatatacggg attgattact ccgatcaagc tgttgaaaac tcaaaaaaag
    13861 caaatatgaa agatgtaaaa acagggaaag taatcattca tcaagctaac gtctcctcta
    13921 ttccttacaa tacgaacttc ttcgatctca ttaccgcctt tcaaactcat tatttttggc
    13981 ccgatgttga acacgatata aaagaagtgc ttcgcgtctt acaaccgaac ggatcctttt
    14041 tattagtggc tgaaactttc aaaattcaat atcatatgaa gaaatttaaa acgacggaag
    14101 aattaataaa ccttttttat aagacgggat ttaaaagtgt gaaatgttat gaagaaagag
    14161 gttgtatctg tgtaatcgga aataagtaaa aaagcagacc cttaagagtc tgctttttta
    14221 ctagattact ttaaagatac tcttaatttg tcttgcaaat aaccaatttt tcgtaccata
    14281 gttatcattt aaactatcta aattgatagt ttgtccgtta gcaaacttta attctaacgt
    14341 tgtatttttg tcatttgttt ttaaattact atttgtaatg gcatcatact ttaatttttc
    14401 aatctcaaca tattcgtctt tttcttgtcc gataacgaca tggtcttgga agaaaaacaa
    14461 tacttctact ttcttaccga agcaaaatac atttttcgta taaattaatg tcgcattatc
    14521 aagtccgaca catacttctt tcatctcttc aacaacgtgt ccaaaatctt cttcctgtct
    14581 tgcgtttgat tccgcaatcc attcctcgat tgttttcatg ttaattgcca tactgcgccc
    14641 cctggttcgt tcattgcttt gttaaaaaac aaatactata tgacaatata agcgatacat
    14701 actttgtttt caagggtgaa ccttatattc aaaataaagt gaaactttaa tcagtaggag
    14761 ggctgttcat cccccactga ttatcagccc tcaccaatcg ggcgtttacg agcaacccga
    14821 ctcccacaaa tagcgggata aagctaaatt tcaaagtaat atacgaggaa cacttatttc
    14881 attatatttt aaacgtttga acgaggcatt cttcatcatc aatcatttgt tttcgttcat
    14941 caaattcaat gtttaactct ctatatactt tcttccaaaa cgaaactgcc ggtacatttt
    15001 ttagaagttc gataacgaaa tactgtcctc gtttctcttc tagtaaattt tcaataactt
    15061 gtttaccgat tccttttccc ctatattgat tcaatatgaa aatgtcattc atacaaaaat
    15121 cgttttcttt cttcaaaaat ggacgttcta ataataataa aaatcctaca atactattat
    15181 caatttttat aaaatatgga gtgattccgt catttttcca aaacaagtgt aaatctttat
    15241 attccaaaaa aaccatttac tccaatcgtt atattagtgg tgaatttgga aaggtcatga
    15301 agatataatg cgtacaaatt acgtaatatt tctttttctg attcttgaac tctttgaagt
    15361 gctacaacca tttttataaa tcgccctctt tattattcaa taaaaaagat tacttccctt
    15421 tacaaaaaaa gtagcacttt aaaagtgcta ctccgctctc cttgctgctt gctgaattgg
    15481 atcccaaacg ctgttatatg gtggtgcgta acttaagtcg acgtcttcta aatcgtgaat
    15541 gctcatttta ttgaaaagcg ccattgcaat cacatcaata cgcttatcta caccttcttc
    15601 cccaattact tgtccaccca acaattgctt cgtatcggag cgatatagca attttaagta
    15661 aagtggtttc gcatttggat aatagcccgc catatttgtt gaatctactt taactgtttt
    15721 atacgggata ttgagccctt tcgcttcttt ttcatttaag cctgttctcg cgagtgtcaa
    15781 atccataaat ttaataatgc ctgtacctaa cgtaccttta aatgatcttc gtttatcaac
    15841 catattgagt ccagcaagtc gtccttgttt attggcagtc gttccaattg gaatatgatc
    15901 atgaatttct tttataacgt gataatgtgt cgcgcaatca ccagcagcat atacgtcttg
    15961 cacattcgtt tgcatatatg catttacttc aattgcccct ttataatttg tacgtatatt
    16021 ggttccttca agaaaatcag tatttggctt tactccgaca gatactaaaa caagatctgc
    16081 tttatacgta cctttatccg tttcaatctc ctctactcgc tcttttcctc taaacgcttt
    16141 tacattttca ttcgttacaa tttcaatatg atgtttatcc gcttctttat gtatatattc
    16201 cgccatatct gcatcataaa tcgtaccgat atgatcattt cgctcaatca tcctcacttt
    16261 tttaccgagt tcaacgaatg tttctgccat ctccagtcca atcgcaccgc cgccaataat
    16321 tgttacgtct tcaactttgt tcgtttctag cgtttttaat atacgctcag tatctggaat
    16381 tgtttttaaa agatgaatgc cttgtaactc tcgtccttcc cattctggca taacaggacg
    16441 cactcccgtc gcaattaata aacggtcata cgtaaattca aaaacatctt tcgtctccgt
    16501 atgctttgcg tacacaattt tcttttccgt atctactttc gttacttcat gtcgcacttt
    16561 cgcatcaatt ccgtacttat cacgaaacgt cttcacgtta cgcgcaatta atttttccgt
    16621 cgaagcaata gcaccactaa tgacatacgg taatccgcac tgagcgtatg aatagatttc
    16681 acctttttct aacgtcacaa cgtttgcagt ttcatcgttt cttacaattt gcatagctgc
    16741 actcatccca gcagcatctc cgccaataat gacatagttc actttaccac tccttctttt
    16801 ttacctactc tttacaattt ccatatttta cagaaataac acctattccc attgtaaaga
    16861 aataatattt catctacaaa tttagtgcac aaacctatgc ctgaataggt aactgtcgtg
    16921 tcttataacc aacatggtta atatgctata acagtaacta ttgaaagtag gtgaaacata
    16981 catgtgccct ggccttctcg ctcaaactcc agatgaaccg caagaaccga aagccgccac
    17041 gccacttgac caagaatttt ccattaacgc aaccatatac agcgctcgtg cttggttatc
    17101 tgacaacgat acctacgcac aagatatttg gaaaggcact cgcttcgctt cagcatcaca
    17161 tgctggtaaa tctatatttc caagtggtac tattaaagtt attaacttat ctgcagatac
    17221 aataacggtt actacatcag gagattcaga tcataatctc aaaacagtcg tagcacccta
    17281 ttctgaagta gctttatcac ctagttcttt atccgccgta caggctagta catcaggaaa
    17341 agcaagtaaa gtcacatttc tctttcacat ctttttctca agagatcctg gtccagctaa
    17401 ataatcatag aaaaggtaca gtaatacaca ctgtaccttt ttcacgaacg ctattctctt
    17461 gatttaatca attcaacatt ataagcttca atatccgtta gctttcctgt aaaatacgga
    17521 ttttctctgt accaagactg ttttgaaaaa tacgcttgca tatctttcgt ttgaaatata
    17581 tttccatgtc ttgcgtatat ttcgtttcta gcaattttca actgttcttt cgttacatac
    17641 gttaaatctg cattcgttaa ttttcgaata tcactatcag ggaagataaa accattgtat
    17701 acatacccag tcgtaggtgg cggagtaaca ttgtaaacga ctgttttttc tacgcttttc
    17761 ttttcgaatg gaaggttata agccgaaagt gctgttaccg tttctacttt tgttgtttcc
    17821 cttccgcttt ctccattgcg ttctaaataa atcgtcgcac ttccatcagt tgctacggga
    17881 ccccacgtaa tttcttctcc ggtcaatgcg gtaactggct tttgattcac atataatgtc
    17941 gcaccaggcg cgttcgtttg aactgtaata tattgccctt gcaacgttaa atctatcgtt
    18001 acattatttt gactttgttt cataagtaca actttttcct cgcgtgatag ttttacatag
    18061 tcatttttat attccacttg aaacacttga gctcctggaa gaaatggtcc atattgcttc
    18121 tgaaaatttt tgtcttctgt cttatcgatt tcttttccgt tcatttttaa agatgcacct
    18181 ttttcatttg aaagcaaagt cgtataatac gtccttgcct tcaatttata tcgatcaaat
    18241 ataaagtaat gtttcccgtc tttcgttaaa gaaaaatccg ctctttcaat tccgtcccct
    18301 tgcttttcac cttgctttaa atattgtttc aattcattca cgtaagacgg attttctttt
    18361 atatatgaaa atagaggctt gaaactctct ctcgttacaa taaccgatgg gtcatctgtt
    18421 gtaataatct cagctaattt ttctccatct ctctcttgta aaatcgtaat catccggtct
    18481 acttgtgcca cctgcgtata atacgatgat ccatacaaat acaatccaac aatcgctata
    18541 acaagtagtg ctaaaaatgt aatgccaatt tttgtaccgc tccccatttt cttcttcact
    18601 actggaattt ctctcttggt accgcagttt tgacaaaatt gcacaccatc tacaaactgc
    18661 gttccacact ttgtacatac attcatccat tcaaccacct ttgcattaga agccagttaa
    18721 tccctgtgta aaggcttgaa ttacagtgct aatgtaagac caaagtacaa taaatgttac
    18781 gattccaatg aaaacatttg cgataagaag tgtgtaaaca agatctaatc cgccattatc
    18841 taattttaat atggctacaa ttatactaat ccctatataa gttgtagcta acgataataa
    18901 tatcggtaag aaaaagatta ataagaaact aaaaagaaaa gtaagaacta atatagcaat
    18961 aaccggcgtt gctatcgttc cccatatgcc gaatacttca agaaacgaaa aagaggattt
    19021 catcatctta ccacttataa aaataatgaa tccaacaaac aaagttaaaa ttaataaaaa
    19081 gaaaaatacc gttacagatt ctccaaaaaa tgtaggagta tatacttctg gcactagcgt
    19141 tctcgtaaca gctgcaccag cactcatcat tctataaaaa atacatgctc ctaaaaaaca
    19201 aataagaaca agactgacaa ttccatttcg cacttcgaca ttgccacttt gcataatcgc
    19261 tgtcggtgct tgaaatgcct gtttaaaaaa ccgaaaatag ccactcgtaa accgctttgc
    19321 ttgctctacc gtttcatttg gacgagtttc cttcgcttgc tctgcatgcg atgattgctg
    19381 attttcttct tggacaccac ttgctactac ttcttcggtt aacgaatgtc cacaattccc
    19441 gcaaaacttt gcttctactg cattttctgt atgacatgct ggacatttca cgctctcatc
    19501 cctccttaag catatatctt ataagatgtt acaagttcaa tatatgactt tggacataaa
    19561 acatgactac aagaaacaga ttatgaaatc ctgcttttga aagaaaatat atagactagt
    19621 aatctagaaa aataatgcta ttatgaaaca gagcaactaa agtgaaactt taaacagatt
    19681 ggatgaaagg caatggaatt tgtaaactca atttttcaaa tactccttac aagcgtgatc
    19741 cagttatttt ctttaattgg agtcatcatt gtaatcggat ttctattagg ttatttagaa
    19801 tctctcacac gaatgtattg gtcgagggct ttcggaagaa aaggatttct tttgactgcg
    19861 tggattggtg ttcctattca tgaacttgga catgccatta tgtgcgtact atttcgtcat
    19921 aaaattgtag caacgcagtt cttcccaaca gatacgagcc aaggtgcgtt aggttacgta
    19981 caacatcaat acaatcaaaa aagtgtatat caacgaattg ggaatttctt cattggaatt
    20041 ggccctatta tttctggtat tactgcatta atccttttca tgcgctattt cgtaccagag
    20101 tcatattttg tatttaatac aactctcgaa aagacgattg catctacttc tattacttta
    20161 gaaatggttc aaaacatgct cttgtcgacg ttcgtattat tgaaaagctt atttacaata
    20221 aacaatttat tgaacccttc cttttggtta tttttattta tcgctatttg tatttctgca
    20281 catatcgctt taagtaaacc agacattaaa ggatccattg acggtgtcat cgtcatgttt
    20341 atcgtattgt ttttatttaa tataatagca gaactttttc agtacgacag taaccaactc
    20401 attgggaaag taatgaaata taatatgtat ctcattgcat tttctagtgt ggcactgctg
    20461 ttctcttgta tttctacact tgttagtttt gggttttata aaataagagg agggcgttca
    20521 ttgtgaaatg cccccgtatt aaaaaagcgc aactaagcaa cctgagttct atatttatat
    20581 ggactcaggt tatttaattt cttttgaaat ctttgatagt tatacaggtg catatatttg
    20641 cgcacagcaa ctttaacctc atcaaaccta ttaataattt aaaacatata aaatacccct
    20701 tttagctttt tctaaaaggg gtattttatt tacatattta atccagcttt taatacccaa
    20761 tatttatttc cattcattgt gagtgagaat tcaatccatc cgtttggatc ttcacgataa
    20821 ataaatacag gtgtacccgt tgctaatgta ccttgatcat ttttcgtaac tgactgactt
    20881 ttaattgtac catcaaatgg atatggtaca acgtaatagg aagtagctag tttaacagtt
    20941 tttgtcgttc cttgtgaata tgttttatat ggaatatcac ttgatagggc gtcgacattt
    21001 aaagagtttg gatttttagg taattttttc gcatatacat aatctttttt ctggaaaggt
    21061 ttaatacgtt ccattatttt tacgatttta gcagaccact cttgatctgt tgaatacatg
    21121 acattcatgc cttttaatgt tggtccgtta aagtatgatc cgtttgcttc taagtacttt
    21181 tctcttacgt agtttgcgtt ataagaaata ctatcaccga aagttggtaa atatttcgca
    21241 tacttaaatg gatcagcatc gtaagcacgt aacccaaata ggttatgttt acgatatgca
    21301 atttcagatt taccatatcc cgattctaaa atagcgtgtg cagctaaata aagagcattg
    21361 acaccatgtt tagcttgagc ttcaacaaag tcattcccat gtccaattaa tgggctgtct
    21421 ggatgatatt ttttaatatt agcatcaatt tctgcaccag tcacatttga agcgtacgtt
    21481 aaatcaagat ctaaatatgt ggtagcagtg atgttatttt caggagtcca agcaccgctc
    21541 ttgtcgaaat ggtacgtcgt tccattgatt gaagcagttc cagtttgcat cataccgttg
    21601 gattgcaaat aataccatgt atcgccatct tgtagccagt ccgtcttcat tgcaccatta
    21661 ttttgtaaat agtaccaact tccatctata aatgaccaac tcgtttgcat tgctccacta
    21721 gcgtttaaat aataccacgt attattcact tgcagccatc cgattttcat tgatccatca
    21781 ttttggaggt aataacggtt gtttccatct tgtagccaac caattttcat tccgccactt
    21841 gaatttaagt aataccactt attattatca agaagccagc cagttttcat agaaccatta
    21901 gaatttaaat aataccaaac tccttgattt aatagccaac ccgtttgcat tgctccgcta
    21961 gcgtttaaat aataccaaac tccttgatct aataaccaac ccgttttcat agaaccatta
    22021 gaatttaaat aataccaaac tccttgatct aatagccagc cagtttgcat tgctccacta
    22081 gcgtttaaat aataccaaac cccttgatca aacagccagc cagtttgcat aatgccgctt
    22141 gaatttaagt aataccattt attattatca agaagccatc ctttttttat agtgccatct
    22201 ggattgaagt aataccattt cccattttgt tgaacccatc cagattgttt tacagcattt
    22261 acatttacag ttgctgtatt agaagttgtt acagtttcag ctaaacctgt tataggaata
    22321 gaaattatac tagatgttaa gacaattgct gcagcttttt taaacatttc ttcctagtac
    22381 tccttttatt aattttttag tttaatagtt atctaactac tattgtaaca aggaagacga
    22441 aaaaaacaac tataacattg tagatattta atagtataat attcgaatta ttaatattga
    22501 gtttttaggg ggaatttata aaggaacatg ttcatagaag gattggaaaa agttgacttg
    22561 taaagtcagc tcgttagttt ttattgtaca tcttcttctt ttttaataag agggtgctgc
    22621 aaaaccctct tattattaat aaatttgatg cttactctcc attataaatt tatatactac
    22681 actctaatta ctcaaagaaa atgttaaatc acattgtttt taattctagt tttgttccag
    22741 ctttttgcat tccctgtttt aagtgctttt tattggacgg aggtgtgttg gcaagcttgt
    22801 aattttttgc ccctaaacga tacccagctc cgaacgaaat aactatacta aaaaacaact
    22861 acattttaag attaatcact ttaccattaa gagaaaattg ttttgcttca actaacaaaa
    22921 tagaatccca aatctctatt ataatattta ctcctgtgga atatttgcta ctccattctt
    22981 tctcattttg taaactcaat ttaacttcac tcagatttgg atcttcataa taaatcgttg
    23041 ttaattctaa ataatctact ttttctctat cataaaatgc aaatctacgc ttttcatcat
    23101 ctttaacata ataaaacgat gacacttcta tcaatactaa tttataatct tttatcactc
    23161 cgttatcaat tacctgcaat gtaaatttaa tattatcatt taacaaatct atatgtgtct
    23221 ctaaaatggt agcgccccat aaatcatcta atatagactg tatattaata ctattcatgt
    23281 agcttttcat ccttttctaa cgttttttat ttaatgtatg acgtatttgc ttataagact
    23341 ttcttaatca attaacacgt gatttgcctt tgtatccttt ataagcacta tagccactta
    23401 tcgctacagg aataagccaa ggtgcctgtc catctggatt tgtcagcatc actggattat
    23461 tatcaccata cgtataccca ttctgcgtta cagaggcatc ctcttca
//
