LOCUS       NZ_CP040605            22051 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Saccharopolyspora sp. ASAGF58 chromosome, complete genome.
ACCESSION   NZ_CP040605
VERSION     NZ_CP040605.1
KEYWORDS    RefSeq.
SOURCE      Saccharopolyspora sp. ASAGF58
  ORGANISM  Saccharopolyspora sp. ASAGF58
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
REFERENCE   1  (bases 1 to 8045912)
  AUTHORS   Guo,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Grain Processing Research Group, Academy of
            National Food and Strategic Reserves Administration, Baiwanzhuang,
            Beijing 100037, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 76.15x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012277335.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:20:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,606
            CDSs (total)                      :: 7,535
            Genes (coding)                    :: 7,265
            CDSs (with protein)               :: 7,265
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 270
            CDSs (without protein)            :: 270
            Pseudo Genes (ambiguous residues) :: 0 of 270
            Pseudo Genes (frameshifted)       :: 80 of 270
            Pseudo Genes (incomplete)         :: 228 of 270
            Pseudo Genes (internal stop)      :: 14 of 270
            Pseudo Genes (multiple problems)  :: 48 of 270
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:54:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6835513
            Orig. end                         :: 6857564
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040605.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22051
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="26"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22051
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22051
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12051](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12051
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     misc_feature    1199..1208
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.35"
                     /tool="antismash"
     misc_feature    1201..1214
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.35"
                     /tool="antismash"
     misc_feature    complement(1202..1215)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.61"
                     /tool="antismash"
     misc_feature    complement(1203..1216)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.43"
                     /tool="antismash"
     misc_feature    complement(1207..1222)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.78"
                     /tool="antismash"
     misc_feature    1210..1225
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.15"
                     /tool="antismash"
     misc_feature    1212..1226
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(1213..1228)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.02"
                     /tool="antismash"
     misc_feature    1245..1263
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(1261..2094)
                     /locus_tag="FDZ84_RS32150"
                     /old_locus_tag="FDZ84_32265"
     CDS             complement(1261..2094)
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011875015.1"
                     /locus_tag="FDZ84_RS32150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32265"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_246868580.1"
                     /transl_table=11
                     /translation="MHPNIVSANFLTDNPVIYEQRFPDPGHLAARFVDDLVHRFGNGRD
                     LLDVGCGTGRDARYWSAHGYRVTGLDSSPQMVEHAQAHCPGADFVVADMRSFETARLLG
                     GHGNPKDPRPRFDVITCLDSAFLYCHSNDDIDAFLRRCHQHLRPGGLLIAEMRNGAFFL
                     GNTELLDEVREQVVVWDGVEYRSRTRLWIDHEDQLLRRERRWDWPGRVEPLTQHSAWRL
                     LFPQELRYFAVRHGFAVVAMFDEPGPRAETPWRRDAELSTRLSGDRLHVVLRRNE"
     gene            complement(2061..3350)
                     /locus_tag="FDZ84_RS32155"
                     /old_locus_tag="FDZ84_32270"
     CDS             complement(2061..3350)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011875016.1"
                     /locus_tag="FDZ84_RS32155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32270"
                     /product="MFS transporter"
                     /protein_id="WP_168588914.1"
                     /transl_table=11
                     /translation="MRTWRLIRSFPPAVQVLLVNQLGVNTGFYLLIPYLAGYLGHDLGM
                     SALLVGVVLGVRNLSQQGLFLLGGSAADRLGARGVIVAGCALRAVGFGVFAFGTSLPVL
                     LLASVLSGLAGALFNPAVRAYLTQEAGDRRAEAFSLFNIFASTGALLGPLLGSALLVAG
                     FRLSAVAAAVVFALLTVAQVAVLPIRRVEPPTTSVLTDWRGVLTDRRFLAFTGALTGMF
                     ALQNQLYLVLPMQAERLTGWSGAVAVIFLVSTAATLALQVRITELFQRRWGRGTSIAVG
                     LGLMGAGFVATAVAAAVVPATPAAGVGEISARLAPVLVTALLLAFGVMLAQPFVYELIP
                     SFGRPELSGTYFGVFYLVSGVTAAAGNALIGWLTDLSGDEWTWLPSTLCVLIGLCSALA
                     VLALDRRGGIGPVRRTGESLCTPTSSAPTS"
     gene            complement(3347..4366)
                     /locus_tag="FDZ84_RS32160"
                     /old_locus_tag="FDZ84_32275"
     CDS             complement(3347..4366)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946051.1"
                     /locus_tag="FDZ84_RS32160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32275"
                     /product="dipeptide epimerase"
                     /protein_id="WP_168588915.1"
                     /transl_table=11
                     /translation="MKLRWVVRSLALREPFRISRSVMSERDAVTVEVEHDGVIGHGEVV
                     TSEYYGLTVERIETELAAAREVLAGVDDPDQIQPLDCAPGVSAALDSALHDLVARLRGV
                     PVFEVLGEARWQPTPTAYTIGIMPTESAARTACELTARGFTVLKVKLGAGEQRRELARL
                     AAIREAAPDTRLLLDPNGAWEPEQAVRMLKAVEEFGIEAVEQPIKPGTPDVLAEVAARS
                     PVPVIADEDAATVDDVRVLGPRVHGVNVKLPKCGGIRAAREIIDLARSNGVDIMLGCLV
                     ASSLGIAPAVHLTGFARWVDLDGHLLLAHDPWTGIGGADGVLRLAGDLGLGVRPAELS"
     gene            complement(4363..5418)
                     /locus_tag="FDZ84_RS32165"
                     /old_locus_tag="FDZ84_32280"
     CDS             complement(4363..5418)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946050.1"
                     /locus_tag="FDZ84_RS32165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32280"
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_168588916.1"
                     /sec_met_domain="PALP (E-value: 8e-51, bitscore: 171.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWGNPDLLGLLRDTPLARVSAALPQPQPGFWAKLECLSAGGMKAR
                     AAVSMLTGACRRGELRPGAAVVESTSGTLGVGLAFAGQALGHPVVLVVDEELEPTMRAL
                     LKAHGARLEVVDRPHPVGGWQQARLDRVQQIRRELPESFWPDQYNNPDNPAGYEAMGEE
                     IARQIDQVDVLVCSVGTGGHSAGTVRAIRRRWPRVRLIGVDTVGSTIFGQPARPRLMRG
                     LGSSIHPRNVAYGQFDEVHWVGPGEAVQACRTLARQAFITGGWSTGAVALVSAWAARVE
                     PGANVVTVFPDGPHRYLSTIFDDDYCRARGLLNRPTANRPVEIAHPAVEATGWTRCRIV
                     SDPLLAMEVPA"
     gene            complement(5418..6218)
                     /locus_tag="FDZ84_RS32170"
                     /old_locus_tag="FDZ84_32285"
     CDS             complement(5418..6218)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946048.1"
                     /locus_tag="FDZ84_RS32170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32285"
                     /product="Rossmann-like domain-containing protein"
                     /protein_id="WP_168588917.1"
                     /transl_table=11
                     /translation="MTPHSVEELTAEVLSGRFGTAGVEVSVGFLTQQGVRHAARERSYR
                     NHVLSLRVEDAVGSCAVEPGEISDEAVLDYVGMPIRELLRSPLLPVRTAALDAYLQWVR
                     PHRSHAEEVVIGRGNSLQKSLHRAKSVVDLLPVGPGRRVLVIGVVNSLLQHLRERGNSY
                     VACDYKGGETEWGEPVTTDAVAALGDCAAVLASGMVVGNGTFQPLLDHARATGKPLVMF
                     AQSASGILPCFLGDGVTAVSAEPYPFFWLDGGPSTIYRYRQEAC"
     misc_feature    complement(5955..5957)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6215..7480)
                     /locus_tag="FDZ84_RS32175"
                     /old_locus_tag="FDZ84_32290"
     CDS             complement(6215..7480)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011875020.1"
                     /locus_tag="FDZ84_RS32175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32290"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_168588918.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 8.6e-14, bitscore:
                     50.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHLLLVESWVGAMSTLLPRSIREGGHRFSFVTRDLQHYLRAKPM
                     TGPHPLLSADNLFTVETNDVQHLLRHLESLQAVLGFDGVLTSCDYYLAAAARAAQRLGL
                     PGAPPEAIERACSKDLTRKALREAGVPGPAFALAETARGLEEAAEALGYPLVVKPVDLC
                     AGMFVRKVDGPAQLREAHAALQGFPVNARGQQRNPVVLLEELLTGPEVSVETVTFRGET
                     TVVGVTDKSVAGEPWFVETGHMFPAALDPDTEEAVAGTAVAAIEALGLDNVVGHTEIKI
                     TPAGPRVVEVNPRPAGNQITELIRRVTGIDLAAVYAQLALGEKPDLHRVDTGAGSAAIS
                     FLLPPREGTITEIGGLDALAADPAVVDWVVKEAGHRTGAAISNNNYLGHVMVTSGSRGE
                     ARRHADSFVAGLDVRYAAEAGE"
     misc_feature    7518..7533
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.81"
                     /tool="antismash"
     misc_feature    complement(7520..7533)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.41"
                     /tool="antismash"
     misc_feature    7520..7534
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 25.36"
                     /tool="antismash"
     misc_feature    7521..7534
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.05"
                     /tool="antismash"
     misc_feature    complement(7521..7536)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.36"
                     /tool="antismash"
     misc_feature    complement(7522..7533)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.23"
                     /tool="antismash"
     misc_feature    complement(7615..7629)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    7630..7645
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            7672..7923
                     /locus_tag="FDZ84_RS32180"
                     /old_locus_tag="FDZ84_32295"
     CDS             7672..7923
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS32180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FDZ84_32295"
                     /product="hypothetical protein"
                     /protein_id="WP_210435257.1"
                     /transl_table=11
                     /translation="MPSGIAVEARDGMAGAMSAAGRLADQAIVLAPAREAFTSGLHAVS
                     IVGATFVILFAVIGMVVPRKRSRPEPEPAACTPEVTAA"
     gene            complement(7930..8676)
                     /locus_tag="FDZ84_RS32185"
                     /old_locus_tag="FDZ84_32300"
     CDS             complement(7930..8676)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693141.1"
                     /locus_tag="FDZ84_RS32185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32300"
                     /product="lipoate--protein ligase family protein"
                     /protein_id="WP_168588919.1"
                     /transl_table=11
                     /translation="MELFRGALGVGADQALEVAVAHAMLRRVSRGESGPALRVYRPGAR
                     VVAFGRRDTLLPGFPGAVRAVRDAGFTPVLRAPGGRAVAYTERSLVVDHVGTDPGYLAG
                     MDERFEGYAELWAGVLRNHGVGARVGAVPGEYCPGAHSVNARGRVKLVGTAQRMVRGAW
                     LFSAVAIFDDAEVLRPLLTDVYRHLDLPFDDDSVGSVAAESPGVSLDDFEAEVVAAYDE
                     RFGLVPTRLADDLLAKAGELTDDHRI"
     gene            8856..9743
                     /locus_tag="FDZ84_RS32190"
                     /old_locus_tag="FDZ84_32305"
     CDS             8856..9743
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681413.1"
                     /locus_tag="FDZ84_RS32190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32305"
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="WP_246868581.1"
                     /transl_table=11
                     /translation="MSGARRDPGKIRGKGSAGARSGQSLRVSTHNALFQQWQALLSNRT
                     KRQRSGEFLIHGVRPITLAVERGWPLRNLLYPSGRKLSSWASRLIDECAVKTVEVHPDL
                     LRELGERESEPPELIAVAELRPDDLDRVPVEQDFLGVVFDRPTSPGNIGTLVRSADAFG
                     ADGLIVSGHAADVYDPKSVRASTGSLFSVPAVRVPSPRSVLDWVTEHRRREVPIAVVGT
                     DENGTSEITECDLTRPVLLVIGNETTGMSTTWQEMCDEVVRVPIGGAASSLNAASAGTV
                     LLYEAARQRGFPVA"
     gene            10001..10696
                     /gene="pqqC"
                     /locus_tag="FDZ84_RS32195"
                     /old_locus_tag="FDZ84_32310"
     CDS             10001..10696
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693144.1"
                     /locus_tag="FDZ84_RS32195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32310"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_168588920.1"
                     /sec_met_domain="TIGR02111 (E-value: 4.5e-83, bitscore:
                     277.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPLGETEFRESLQRLAKRYWARHPFHRRLHDGRCSQPEVRLWV
                     ANRWYYQRHLSQKNAAIAANCPLPEVRRIWVERIGFQDGSSDADGGLHDWLVLAEAVGL
                     QRSEVLDERHVLPGVRFAVDAYLDFCRRKPWIEGVAAALTEMFSPDHMSDRMAAWRRHY
                     HWIEPGGLAYFERRIPAARADSTLTLQVVLDHCETREQQDAAVRALAFKCDVLWAMLDA
                     IDYKGQSWT"
     gene            10687..12051
                     /gene="pqqE"
                     /locus_tag="FDZ84_RS32200"
                     /old_locus_tag="FDZ84_32315"
     CDS             10687..12051
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693145.1"
                     /locus_tag="FDZ84_RS32200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32315"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_168588921.1"
                     /sec_met_domain="PqqD_RRE (E-value: 2.5e-19, bitscore:
                     67.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-10, bitscore: 38.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1e-19, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.8e-05, bitscore: 23.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.1e-07, bitscore: 30.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.1e-08, bitscore:
                     33.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVTADGRPGLRRGVRFVHDRVRARHALLYPEGVLLLNDTAADIV
                     SRCDTKRTVTEIVSELTAAYQGVTAESVLEMLADLARRRMLGAEPAEVAESGPQQEEPR
                     SGLPLGLLAELTYRCPLQCTYCSNPLNLADYQDELDTEDWLRVIEQARSIGVLQLHLSG
                     GEPALRRDLVPLVAAARGLGIYTNLVTSGFSLPPKRLHELAEAGLDHIQLSVQDSAAMP
                     ADAIAGRRAHARKMIVARSIAETGLPMTVNAVLHRGNIARLLDIVELAADFGAERVELA
                     NTQFYGWALRNRAALMPRREQVQRGDADAALARERYGDRLEIVYVTADYFSPRPKPCNY
                     GWGSRQLTVAPNGDVLPCLAAGQLPGLDAPSVRDSTLEAVWFDSAAFNRFRGTEWMPDP
                     CRSCALKDVDFGGCRCQAYQLVGDAAVTDPACSLSEHHDLIRTEFQPQPAVPRRM"
     aSDomain        10693..10944
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FDZ84_RS32200_PqqD_RRE.1"
                     /evalue="9.40E-22"
                     /identifier="RREFam006.1"
                     /label="FDZ84_RS32200"
                     /locus_tag="FDZ84_RS32200"
                     /protein_end="86"
                     /protein_start="2"
                     /score="67.6"
                     /tool="antismash"
                     /translation="VTADGRPGLRRGVRFVHDRVRARHALLYPEGVLLLNDTAADIVSR
                     CDTKRTVTEIVSELTAAYQGVTAESVLEMLADLARRRML"
     gene            12051..12920
                     /gene="pqqB"
                     /locus_tag="FDZ84_RS32205"
                     /old_locus_tag="FDZ84_32320"
     CDS             12051..12920
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013229609.1"
                     /locus_tag="FDZ84_RS32205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32320"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_168588922.1"
                     /transl_table=11
                     /translation="MRVRVLGTAAGGGLPQWNCSCQSCCRAAELGVQLSQDCLAISGDG
                     NSWYLVNASPDLRTQLLATPELRPPPGTRRTPVEGVLLTSAELDHTLGLLTLRESSRLP
                     IYATAAVHQALQQAFPITEVVGSYTTVQPEIVSDRQVLAGGLAAEIAVVGDKRPRYAGD
                     LRGTDWVVAYRFTGSGRSLVYAPCLPAWNDAFEQVIDGADVVLLDGTFFTEDELTHASG
                     SDRPASSMGHLPIRAALPEIARHPRTRFLFTHLNNTNPLAHPDAPELAEVRAAGAEIAA
                     ERQLLVLE"
     gene            12966..14552
                     /locus_tag="FDZ84_RS32210"
                     /old_locus_tag="FDZ84_32325"
     CDS             12966..14552
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693150.1"
                     /locus_tag="FDZ84_RS32210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32325"
                     /product="DNA polymerase ligase N-terminal
                     domain-containing protein"
                     /protein_id="WP_168588923.1"
                     /transl_table=11
                     /translation="MNDERLAKYREMRDFTRTAEPSGDGEVRATGDRFVVQRHRARRRH
                     YDLRLEFDGVLLSWAVPKGPTLDPSARRMAVQVEDHPLEYADFEGTIPAGEYGGGDVIV
                     WDRGTWEAVEDDPAAAIEAGTLHFDLHGDKLVGRFVLVRRGEKQWLLLHKKDEHAEPGW
                     NPEDHPRSVKSGRTNEEVAAAPEAMWRSDLPPSEAEIPLGANKSRAKAHWDPPTGEELA
                     ALDELGSKGRWRLAGRNLALTNLDKVLFPARDDEAPVTKRDLIRYHALIAPVMLPYLAD
                     RPLNSHRFPNGVDEPGFWHKEVPSHAPDWLRRWRYEDADPDDTQWYLIPDSVPALAWLA
                     NYAALELHAWTSRASDVHHPTWALFDIDPGSRTTFEEVLVLARLHRTAMEHLGVEARPK
                     VTGQRGIQIWVPVEPRYTYAETRAWVEKVSKAVGGTVPELVSWAWTKTDRRGLARLDYT
                     QNVINKTLVAPYSARPRPGAPVSVPLEWDELDDPDLAPDRWTIRTVLDRIATVGDPFAA
                     LLDVEQQLPPV"
     gene            14711..15253
                     /locus_tag="FDZ84_RS32215"
                     /old_locus_tag="FDZ84_32330"
     CDS             14711..15253
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017985913.1"
                     /locus_tag="FDZ84_RS32215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32330"
                     /product="esterase-like activity of phytase family protein"
                     /protein_id="WP_168588924.1"
                     /transl_table=11
                     /translation="MQIRTRSAVLAAAALLFLAPAAFPAAAQESASSRLLGTYVVPHDL
                     RVDGTPVGGLSSVDYDRRSGDFIFVSDDWSDHAPARYYRADVSVTERGVEDVTFTGASL
                     FRRPDGTTYPAIDIWRGAVQKKLLVDLDEIGVPYTDNVEGISWGPLLPTGERVLLVVSD
                     NNFSPNQQTQLIAIAVR"
     gene            complement(15394..16605)
                     /locus_tag="FDZ84_RS32220"
                     /old_locus_tag="FDZ84_32335"
     CDS             complement(15394..16605)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693156.1"
                     /locus_tag="FDZ84_RS32220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32335"
                     /product="cytochrome P450"
                     /protein_id="WP_168588925.1"
                     /sec_met_domain="p450 (E-value: 2.3e-21, bitscore: 74.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAAERLQLPFERPNVLDLAPLYEVLRREAPVTPVTAPAGDPAW
                     LVTRFDEVRELLSDKRLGRSHPEPERASRITTAAVQDGPTGNYETEEADHARMRRLLTP
                     AFSAKRMRMLSGHMQDLVDDYIDQLVAEHDAAPDGIVDLHAGLAFPLPVAVICQLLGVP
                     ESDREHFRSLSDRMASYASGDDAHQARAEFGKYMARLAEGKRAEPGEDIISDIVRAQSA
                     DERFDYDEMVRLCVGLLFAGHETTVNRIGLGTLLLLTRPDQWQSLTADPTGRVNATIEE
                     IMRLGAPGDLGLLRYAHTDLDVAGTTIHRGDAVILSINAANRDQAAYSNAETFDPDREE
                     RAHLGFGHGSHFCIGASLARTELRIVFATLAQRLPGLRLAKDLDELEVRTTITGGVTEL
                     PVTW"
     misc_feature    complement(15838..15840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16738..17406
                     /locus_tag="FDZ84_RS32225"
                     /old_locus_tag="FDZ84_32340"
     CDS             16738..17406
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010225317.1"
                     /locus_tag="FDZ84_RS32225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32340"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_246868582.1"
                     /transl_table=11
                     /translation="MVERHDRRIRRGRPPVSDQQRQQQRLDISRHAVRLFREQGVAATS
                     GEQIARAAGVSERTLWRYFRSKESCVEPLLTKTIDAFQEVLRTWPPELELAEHLRAAYT
                     PVLDSSDSDVEAVLAVVRMTHDEPTLRAAYLVLRERDESAFADVLAERMGMPSDALEVR
                     MQAAATSAALRAATDHLVSIATEGISPETFSEHRERLADALRLVTSSGRLKPPDSNQQR
                     "
     gene            17768..18022
                     /locus_tag="FDZ84_RS32230"
                     /old_locus_tag="FDZ84_32350"
     CDS             17768..18022
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="FDZ84_RS32230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32350"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_246869263.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.5e-07, bitscore:
                     28.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3e-06, bitscore: 25.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPGRSRRWRDAPRVSKPSGPNTGPALVVVGEEDTLTPPENAREL
                     AGALSGSELVTLPGAGHLPSIESPDAFAEAVRPRLSRLG"
     gene            complement(18346..18828)
                     /locus_tag="FDZ84_RS32235"
                     /old_locus_tag="FDZ84_32355"
     CDS             complement(18346..18828)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693158.1"
                     /locus_tag="FDZ84_RS32235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32355"
                     /product="hypothetical protein"
                     /protein_id="WP_168588927.1"
                     /transl_table=11
                     /translation="MTIWGALAGGFIGTLVLTTALRAANELKLTRIDIPFLLGTCVTVN
                     RSRAKALGYLAHFVFGELFALGYYGLFVALGTSSWWLGALFGLVHGMFAGTALVNLLLP
                     VVHPRMGTNLTSAPQSALLEPPGFLLLNYGVVTPIVSLLGHVLYGALVGGFISYTS"
     gene            complement(18825..20660)
                     /locus_tag="FDZ84_RS32240"
                     /old_locus_tag="FDZ84_32360"
     CDS             complement(18825..20660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693159.1"
                     /locus_tag="FDZ84_RS32240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32360"
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="WP_168588928.1"
                     /transl_table=11
                     /translation="MIGSDLGNGPRVAAPRWEGYAPLREYAALGDGRTVALLARDGSVD
                     WLTMPDLDSPTVFGAVLDARRGGCFALQPELPYQVSRRYLPSTNVVETTFTTAAGAVRV
                     TDALTLPGGALTPTRELVRKVEGLSGAVPMRWSVQPRFGYGAASPCISRRAGLPVASAG
                     TDALAVCTWGAGEPLCAGDEIEGAFEIRLGSRADLALSFAHEEPLVVPARAECAARLEE
                     TGHRWRAWLRDRACAGRWQKAVTRSALALKLLVYAPSGAVAAAATSSLPEEIGGERNWD
                     YRFSWLRDSVFTLDALLTLGCPSEAQAYFWWLMHATQFNEPRLRPLYRLDGGVGASERV
                     LALEGYRGSAPVRVGNAAAEQLQLDTYGELLQTAWLYATASGQLDPDIARRLARVADFV
                     CASWRQPDEGIWEVRSPPQHFTQSKMMCWIALDRALRLAERGLLSRRHAPAWRREQAVI
                     EDFIETRCLSENLNSYVRSADAEEVDVSVLLGLLRGYASPQHPRMHGTIEAIRRDLAHG
                     PFVYRYGGDDGLQGTEGAFVACSFWLAEALARCGHLGEAAELMDQLVGLANDVGLYSEE
                     IDPNTGEFLGNMPQGLTHLALISAACAITEQGMTR"
     gene            complement(21041..21889)
                     /gene="purU"
                     /locus_tag="FDZ84_RS32245"
                     /old_locus_tag="FDZ84_32365"
     CDS             complement(21041..21889)
                     /EC_number="3.5.1.10"
                     /GO_function="GO:0008864 - formyltetrahydrofolate
                     deformylase activity [Evidence IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="purU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010693162.1"
                     /locus_tag="FDZ84_RS32245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_32365"
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="WP_168588929.1"
                     /transl_table=11
                     /translation="MSHTCTLTLSCPNRTGIVRAVSGYLFEHGCDIGEHQQFDDAVRDR
                     LFMRTQVTAPGGTDLEELSRGFATVAAEFEMTYDFNANRNARILVMASKLGHCLNDLIY
                     RWRAGSLGGDIVAVVSNHQDLRPMAEAAGLPFVHIPVTPATKEAAEARLLQLVDEYDAE
                     LVVLARYMQILSDETSKALYGRAINIHHSFLPGFKGAKPYHQAYQRGVKLVGATAHYVT
                     SDLDEGPIIEQEVIRIDHTYDPRALQTVGRDAEALALSRAVRWHCERRVLLNGHSTVVF
                     P"
     misc_feature    complement(21989..22009)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
ORIGIN
        1 gcctgcctgg cctggtcgct gatggccagc gccgcctcct tcagcccggt cgaggtgtcg
       61 gaggtgtcga ggtcgatcgt caggccctcg gcgcccgcct gcttgatcag ggcacgggcc
      121 ctgtcgaggt cctgggtgcg ctgcggcagc gcgtcggcgt agtaccggta gcccttgcca
      181 taaacgtcgt tgcagagttg cccggagccc tgcagcacgg acctgaccag ctcgtcccgg
      241 ttcaccaggt ggaacatcgc ctggcgcagc tcgggtcggt cgaacggcgg ccggtcggtc
      301 ttcatgacca ggccgtggaa gttgctcagc ggcagccggt gcacccgcac ccggccggtg
      361 ttctcgtgcg tgcgggcgct ggtcggggtc aggtcgtggg cgtactcgac ctggcctccc
      421 agcagcgcgt tgacccgggc cgcctcgtcg ttggtcacga cgatctccag ctcgtccagg
      481 tgcggtgttc cctcccagta gtcggggttg cgggccgcca cgaagttgcg gccgggcgcg
      541 aaggagacga accggaacgg gccggagccg accggccggt cgaagtcagt cgtgccctcc
      601 gggatgatgt aggcgcccag ggtggcgagc gcgttgggga actccgcgta cggccgcttg
      661 aggcggaact cgacggtgcg gtcgtcgatc gcgcggctgc ccggcaggtc gatcaccgca
      721 agactggcct tcgccctgcg gctgctgctc ggctccacga tccgcgcgta gctggccagc
      781 acgtcactgg cgcgcaccgg tcggccatcg tgaaaagccg cctgccgtaa cgtgatccgc
      841 caggcgagca ggtcctggct ggcctcccag cgctccgcca gccggggctg cggggacatg
      901 tccgagccgt agtcggcgag cttctcgtag agcgccttgg cgcgggcgat ctcgatgtag
      961 aggtcggttt cgtgcgggtc gagcacctct gccgcgccac cgccggagaa cgccgcacgc
     1021 aaccggccac cgggacgcgg tgggccgacc gctgcgactc cggctcggcc ggcgcagccg
     1081 acgagcaccg ctacggaacc cgccgccgtc aggcccagga agccgcgtcg gctcaggccg
     1141 cgagcaggtc cggattcgtg catgctgcgt ttctccattc gatgtcggcc cacgccgaga
     1201 atttttgata acgatattgg ttttcattta agtcgccaag ggactgcgct gaggcgcgcc
     1261 tcactcgttg cgccgcagca ccacgtgcag ccgatcgccg ctgagccggg tggacagctc
     1321 ggcgtcgcgc cgccacgggg tttcggcgcg cgggccgggc tcgtcgaaca tcgcgaccac
     1381 cgcgaacccg tgccgaaccg cgaagtacct tagttcttgg gggaacagca gccgccaggc
     1441 cgaatgctgg gtcaacggct cgacgcgtcc cggccagtcc cagcggcgtt cccgccgcag
     1501 gagctggtcc tcgtggtcga tccacaggcg cgtgcgcgac cggtactcca ccccgtccca
     1561 gacgaccacc tgttcccgga cctcgtcgag cagttcggtg ttgcccagga agaacgcgcc
     1621 gttgcgcatc tccgcgatca gcagcccacc cggccgcagg tgctggtgac atcgccgcag
     1681 gaaggcatcg atgtcgtcgt tggagtggca gtacaggaac gcgctgtcca agcaggtgat
     1741 gacgtcgaac cggggccgtg ggtccttcgg gttgccatga ccgcccaaaa gcctcgcggt
     1801 ctcgaacgac cgcatgtcgg ccaccacgaa atccgccccc gggcagtgcg cctgcgcgtg
     1861 ctccaccatc tgcggcgagg agtccaggcc cgtgacccgg tagccgtgcg cgctccagta
     1921 gcgggcgtcg cggccggtgc cgcagcccac gtccagcagg tctcgcccgt ttccgaagcg
     1981 gtgcacgagg tcgtcgacga accgcgccgc gaggtgtccg gggtccggga agcgctgctc
     2041 gtagatgact gggttgtcgg tcaggaagtt ggcgctgacg atgttggggt gcaaagggat
     2101 tctcccgttc tccggactgg cccgatacca ccgcgccgat ccagcgccag cacggccagc
     2161 gccgagcaca gtccgattag gacgcacagt gtcgagggca accacgtcca ctcgtcgccg
     2221 gagaggtcag tcagccagcc gatcagcgca ttgccagctg cggcagtcac cccggaaacc
     2281 aggtagaaga cgccgaagta ggtgccggac agctccggcc gcccgaacga cgggatcagc
     2341 tcgtagacga agggctgcgc gagcatcacg ccgaacgcca gcaacaacgc cgtgaccagc
     2401 acaggggcaa gtcgggcgga gatctcgccg acgcccgccg caggcgttgc ggggacgacg
     2461 gctgcggcca ccgcggtggc gacgaaaccc gcgcccatca gccccaagcc gacggcgatg
     2521 gatgtgccgc ggccccaccg gcgctggaac agttcggtga tccgcacctg caacgccagg
     2581 gtcgccgccg tggagaccag gaagatcacc gccacggcac cggaccagcc ggtgagccgc
     2641 tcggcctgca tcggcaacac cagatagagc tggttctgca gggcgaacat gccggtgagc
     2701 gccccggtga aggccaggaa ccggcgatcg gtgaggaccc cgcgccagtc ggtcagcacc
     2761 gaggtcgtgg ggggctcgac gcggcgaatc ggcagcaccg cgacctgcgc gacggtcagc
     2821 agcgcgaaga ccaccgcggc ggccactgcc gacagccgga acccggccac cagcaacgcg
     2881 ctccccagca acggccccaa caaggccccg gtgctcgcga agatgttgaa cagcgaaaac
     2941 gcctcggcac gccggtcacc cgcctcctgc gtgagatagg cgcgcacggc cgggttgaaa
     3001 agcgccccgg ccaacccgct cagcacagat gccagcaaca acaccggcaa cgacgtgccg
     3061 aacgcgaaca cgccgaaacc caccgcgcgc aacgcgcacc cggcgactat gacgccccgc
     3121 gcgcccaacc ggtccgctgc cgaaccgccg agcaggaaca gcccctgctg gctgaggttg
     3181 cgcacgccga gcaccacccc gaccagcaac gccgacatgc ccaggtcgtg gcccaggtac
     3241 ccggccaggt acgggatcag caggtagaag ccggtgttga cgccgagttg gttgaccagc
     3301 agcacctgca cggccggcgg gaagctccgg atcagccgcc aggtcctcac gacaactccg
     3361 ctggacgcac tcccagcccg agatcgccgg cgagccgcag caccccgtcg gcaccgccga
     3421 tcccggtcca cgggtcgtgc gccaacaaca ggtgcccgtc caggtcgacc cagcgggcga
     3481 acccggttag gtgcaccgcc ggagcgatac cgagcgaact cgccaccagg cacccgagca
     3541 tgatgtccac gccgttactc cgggcgaggt cgatgatttc ccgcgcggcc cggattccgc
     3601 cgcacttcgg cagtttcacg ttgacgccgt gcacccgcgg ccccaggacg cgcacatcat
     3661 cgacggtggc ggcgtcctcg tccgcgatga ccggcaccgg cgaccgagcg gccacctccg
     3721 cgagcacgtc cggcgtgccc ggcttgatcg gttgctcgac cgcttcgatc ccgaactcct
     3781 cgacggcctt gagcattcgc accgcctgct cgggttccca cgctccgttc gggtccagca
     3841 gcaggcgggt gtcgggggcg gcctcgcgga tcgccgccag acgggcgagt tcccgccgct
     3901 gctcccccgc gccgagcttg accttgagca cggtgaagcc ccgggcggtg agctcgcacg
     3961 cggtccgcgc ggcggactcc gtcggcatga tgccgatcgt gtaggccgtc ggcgtcggtt
     4021 gccagcgggc ctcacccagc acttcgaaga ccggcacgcc gcgaagcctg gcgacaaggt
     4081 cgtgcagcgc cgagtccagc gcggccgaca cgccaggcgc gcagtccagc ggctggatct
     4141 ggtccggatc atccacgcct gccagcactt cgcgggcggc ggccagctcc gtctcgatgc
     4201 gttcgaccgt cagcccgtag tactcgctgg tgacgacctc gccgtggccg atgacgccgt
     4261 cgtgctcgac ctccaccgtg accgcatctc gctcggacat caccgatcgg gagatgcgga
     4321 acggctcacg cagcgcgagg ctgcgcacca cccaccgcag cttcatgcgg gaacctccat
     4381 cgccagcaac ggatccgaga cgatccggca cctcgtccac cccgtcgcct ccaccgcggg
     4441 gtgcgcgatc tccaccggcc ggtttgccgt cggccggttc agcaggccac gcgcgcggca
     4501 gtagtcgtcg tcgaagatcg tgctcaggta gcggtgcgga ccgtcgggga acaccgtcac
     4561 cacgttcgcg cccggctcga cccgcgccgc ccaagccgaa accagcgcca ccgccccggt
     4621 gctccagccg ccggtgatga aggcctgcct ggcgagcgtg cgacaggcct gcaccgcctc
     4681 gccagggccg acccagtgca cctcgtcgaa ctgtccatat gcgacattgc gcgggtggat
     4741 actgctgccc agtccgcgca tcaagcgcgg ccgggcgggc tgaccgaaga tcgtcgagcc
     4801 gacggtgtcc accccgatca gccgcacccg cggccagcgg cgccggatcg cgcggaccgt
     4861 gcccgcgctg tgcccgccgg tgccaacgct gcacaccagc acgtccacct ggtcgatctg
     4921 ccgggcgatc tcctcgccca tcgcctcgta acccgccggg ttgtccgggt tgttgtactg
     4981 gtccggccag aacgactccg gcagctcgcg gcggatctgc tgcacccgat ccagccgggc
     5041 ctgctgccat ccgccgacgg ggtgcggcct gtcgaccact tcgaggcgcg cgccgtgcgc
     5101 cttgagcagg gcccgcatgg tcggctccag ctcctcgtcc acgaccagca ccaccggatg
     5161 tcccagcgcc tgcccggcga aggccaggcc gacgccgagc gtcccgctgg tcgactccac
     5221 cacggccgct cccggccgca gctcgccgcg gcggcaggcc ccggtgagca tcgacaccgc
     5281 cgcacgggcc ttcatcccgc ccgcgctcag gcactcgagc ttcgcccaga agcccggctg
     5341 cggttgcggc agcgcggcgc tcacccgcgc cagcggcgtg tcccggagca ggccgagcag
     5401 atccggatta ccccacatca gcacgcctcc tggcggtagc gatagatcgt gctggggccg
     5461 ccgtcgagcc agaagaacgg atagggctcc gccgagacag cggtgacccc gtcgcccagg
     5521 aagcacggca agatgccgct cgcggactgc gcgaacatga ccagcggctt gcccgtggcc
     5581 ctcgcgtggt cgagcagcgg ttggaaagtg ccgttgccga cgaccatgcc cgaagccagc
     5641 acggcggcgc agtcgccgag ggccgcgacg gcatcggtgg tgaccggctc gccccactcg
     5701 gtttcgccgc ccttgtagtc acacgcgacg tagctgttcc cgcgctcgcg gaggtgctgc
     5761 agcagcgagt tcacgacgcc gatgaccagc acccgccgac ctggcccgac tggcagcagg
     5821 tccaccaccg atttggcgcg gtgcaacgac ttctggagcg agttcccccg gccgatgacg
     5881 acttcctctg catggctgcg atgcgggcgc acccactgca ggtaggcgtc gagcgcggcg
     5941 gtgcgcaccg gcagtaacgg gctccgcaag agctcccgga tcggcatccc gacgtagtcg
     6001 aggacggctt cgtcggatat ctcgcccggt tccaccgcgc acgaccccac cgcgtcctcg
     6061 acccgcaggc tcagcacgtg gttgcggtac gagcgttccc tcgccgcgtg ccgcacgccc
     6121 tgttgcgtca ggaacccgac gctgacctct acccctgcgg ttccgaatcg tccgctgagg
     6181 acctctgcgg tcagttcctc taccgaatgc ggcgtcactc gccggcctcc gcggcgtagc
     6241 gcacgtccag accggcgacg aacgaatcgg cgtgacgccg cgcctcgccc cggctcccgc
     6301 tggtgaccat cacatgcccg aggtagttgt tgttgctgat agctgcgccc gtccggtgcc
     6361 cggcctcctt gacgacccag tccaccaccg cgggatcggc tgccagcgcg tcgagcccgc
     6421 cgatctcggt gatggttccc tccctgggcg ggagcaggaa cgagatcgcc gcacttcccg
     6481 caccggtgtc gacgcggtgc agatcgggct tctcccccaa cgcgagctgg gcgtagacgg
     6541 ccgccaggtc gatgccggtc acccgccgga tgagctcggt gatctggttt cccgccgggc
     6601 gcgggttcac ctcgacgacc cggggccccg ctggtgtgat cttgatctcg gtgtgtccga
     6661 cgacgttgtc cagcccgagc gcttcgatgg cggcgactgc cgttcccgcc actgcttcct
     6721 cggtgtcggg atcgagcgcg gccgggaaca tgtgcccggt ctcgacgaac cacggctcac
     6781 cggcgacgct cttgtccgtc acaccgacga ccgtcgtttc accccggaac gtgaccgtct
     6841 cgacgctcac ctccggaccg gtgagcagct cctccagcag cacgaccgga ttccgctgtt
     6901 gcccgcgggc gttcaccggg aagccctgta gggcggcgtg tgcctcgcgc agctgcgccg
     6961 gtccgtccac tttgcgcacg aacatgcccg cgcacaggtc gaccggtttg accacgaggg
     7021 ggtatcccag cgcttcggcg gcttcttcga gtccgcgggc ggtctcggcg agggcgaacg
     7081 ccgggcccgg cacaccggcc tcacgaaggg ccttgcgggt gaggtccttg gagcatgcgc
     7141 gctcaatcgc ttccggcggc gcccccggca gccccagccg ttgggcggcc cttgctgctg
     7201 cagccaggta gtagtcgcag gacgtcagca ccccgtcgaa tccgaggact gcttgcaggc
     7261 tctcgaggtg gcgcagcaag tgctggacgt cgttggtctc gaccgtgaac aggttgtcgg
     7321 cgctcagcaa cggatgcggg ccggtcatgg gttttgcacg caggtagtgc tggaggtcgc
     7381 gggtgacgaa gctgaatcgg tggccgccct ctctgatgct ccgcggcagc aacgtgctca
     7441 tcgcacctac ccagctttcc accaacaaca ggtggcccac gccaactccc tccgagcggt
     7501 tatgatcaac gatcggcgat gataatcgtt ttcactctgg tgcggcaact cgccctcgga
     7561 tgaataaccc gcgcccaccg acgaaaccga ccgtcaccag ggaggttggt cgggtggccg
     7621 aatccctcgt ccaatacgtg ttcggactgt ggcgtcgcga ttccggcgga agtgccctct
     7681 ggcatcgcgg tcgaggcccg agacgggatg gccggcgcga tgagcgcggc ggggcggctg
     7741 gccgaccagg cgatcgtgct cgccccggca cgagaggcgt tcaccagcgg tctccatgcg
     7801 gtttccatcg tcggcgccac cttcgtgatc ctcttcgcgg tcatcggcat ggtggtgccg
     7861 cgcaagcgct cccggcccga gccggaaccg gcggcctgca cacccgaggt gaccgccgcc
     7921 tgaacgcctt tagatgcggt ggtcgtcggt cagctcgccg gccttggcca gcaggtcgtc
     7981 ggccaaccgc gtcgggacca agccgaatcg ttcgtcgtag gccgcgacga cctctgcttc
     8041 gaagtcgtcg agtgatacgc cgggcgactc cgcggccacc gagcccaccg agtcgtcgtc
     8101 gaagggcaga tccaggtgcc ggtagacgtc ggtcagcagc gggcgcagca cttcggcgtc
     8161 gtcgaagatc gccaccgcgc tgaacagcca tgcgccccgc accatccgct gcgccgtgcc
     8221 gaccagcttc acgcggcccc tcgcgttcac gctgtgcgcg cccgggcagt actcccccgg
     8281 caccgcaccg acccgcgcgc cgacgccgtg gttgcgcagc accccggccc acagctcggc
     8341 gtagccctcg aaccgctcgt ccatgcccgc caggtaaccg gggtcggttc cgacgtgatc
     8401 gaccaccagc gaccgctcgg tgtaggccac cgcacgtccg cccggggcgc gcaggaccgg
     8461 cgtgaacccg gcgtcccgaa cggcgcggac cgcgccggga aagccgggca gcagcgtgtc
     8521 ccgccgtccg aaggcgacga cccgggcgcc cggccggtac acccgcaacg caggacccga
     8581 ctcgcctcgg ctgacgcggc gcaacatcgc atgcgctacc gcgacctcca gcgcctgatc
     8641 cgcgccaacc ccgagcgcac cgcgaaagag ctccacgggc cgattctact ggccggaaga
     8701 tcgccagctc accggccgaa gcccgggcga gctctggagc cttgaacccg gcggtccaca
     8761 ccacgttgtc ggcgccgagc tgtccgccgt cggccagcac caagccggcc gcgcgccgcg
     8821 aagtcgtctt ccgcagtgcc tgttagcctt gcacggtgtc aggcgcaaga cgtgatccgg
     8881 ggaaaatccg cggcaagggc agtgcaggcg cgcgttccgg ccaaagtctt cgcgtcagca
     8941 cccacaacgc acttttccag cagtggcaag cactgctgtc gaaccgcacc aagcgacagc
     9001 gttccggcga gttcctgatc cacggtgtgc gaccgattac gctcgcggtg gagcgcggtt
     9061 ggccactgcg caatctcttg tacccgtcgg gcaggaagct ctcctcctgg gccagccggc
     9121 tgatcgatga atgcgccgtc aagaccgttg aagtgcaccc ggatctgctc cgggaactcg
     9181 gcgagcgcga atccgaacca ccggaactca tcgccgtcgc cgagctgcgg cccgacgacc
     9241 tcgaccgggt gccggtggag caggacttcc tgggcgtggt cttcgaccgg cccaccagcc
     9301 cgggcaacat cggaaccctg gtgcgctccg cggacgcctt cggcgccgac ggcctgatcg
     9361 tgagcggtca tgccgcagac gtctacgacc cgaagtcggt gcgcgcgagc actgggtcgc
     9421 tgttctcggt gcctgcggtc cgggtgccgt caccgcgcag cgtcctcgac tgggtcaccg
     9481 aacaccggcg gcgcgaggtg ccgatcgcgg tcgtcggcac cgacgagaac ggcacctccg
     9541 agatcaccga atgcgatctc acccggcccg tcctgctggt tatcggcaac gagacaaccg
     9601 ggatgagcac cacctggcag gaaatgtgcg acgaggtcgt ccgggttccc atcgggggcg
     9661 ccgcgagttc gctgaatgcg gcctcagcgg gaaccgtgct gctttacgag gctgcccggc
     9721 agcgcggttt tcccgttgct tgagccgggc ggcgaaattc gcggctgatc ggcggtaccg
     9781 gttgcggcgg tcgtgttgtt cgcggttcgg aatcttgatt ccggtggttc ggcactagta
     9841 cggtccgatt tcgcttgtcc ttcttgctaa atggaggtct tgtgatggcc gctccttcgg
     9901 aatccgttcc cgcccccgct ccgccgagct ggaccccacc gctggtcgaa caatacgaaa
     9961 cccgtcccga ggtcaccgct tacgcgcacg acggcagtcg gtgagccagc cgctgggcga
    10021 gaccgagttc cgggaatcct tgcagcggtt ggcgaagcgt tactgggcgc gccacccgtt
    10081 ccaccggcgc ttgcacgacg gccgctgcag ccagccggag gttcggctgt gggtggccaa
    10141 ccggtggtac taccaacggc acctgtcgca gaagaacgcc gccatcgcgg cgaactgccc
    10201 gcttccggag gtgcggcgga tctgggtcga gcggatcggc ttccaggacg gatccagcga
    10261 cgccgacggc ggcctgcacg actggctggt gctcgccgaa gcggtcggcc tgcagcggtc
    10321 cgaggtcctc gacgagcgcc acgtgctgcc cggcgttcgg ttcgccgttg acgcgtatct
    10381 ggacttttgc cggcgcaagc cgtggatcga gggtgtggcc gcggcgttga ccgagatgtt
    10441 ctcgcccgat cacatgtccg accggatggc ggcctggcgg cgccactacc actggatcga
    10501 acccggcggg ctggcctact tcgagcggcg gatcccggcc gcccgcgcgg acagcaccct
    10561 gacgctgcag gtcgtgctcg accactgcga gacgcgcgag cagcaggacg ccgcggtgcg
    10621 ggcgttggcg ttcaaatgcg atgtgctttg ggcgatgctg gacgccatcg actacaaggg
    10681 acagtcatgg acgtgaccgc cgacggccgc cccgggctgc ggcgcggtgt ccggtttgtg
    10741 catgaccgcg tccgcgcgag gcacgccctg ctgtacccgg aaggtgtgtt gctgctcaac
    10801 gacaccgcag ccgacatcgt gagcaggtgc gacaccaagc gcacggtcac cgaaatcgtc
    10861 agcgagctaa cggccgcgta ccagggcgtg accgccgaat ccgtgctcga aatgctcgcg
    10921 gacctggcgc gtcgccgaat gctgggggcg gaaccggccg aggtggcgga atccggtcca
    10981 caacaggagg agccgcgatc cggactgccc ctgggcttgc ttgccgagct gacctatcgg
    11041 tgcccgttgc agtgcacgta ctgctcgaac cccttgaacc tcgccgacta ccaggacgaa
    11101 ctcgacaccg aagactggtt gcgcgtcatc gagcaggctc ggtcgatcgg cgtactgcaa
    11161 ctgcacctct ccggtggcga accggcactg cgccgggacc tcgttcccct cgtcgcggcg
    11221 gcccgcggac tcggcattta cacgaacctc gtcaccagtg ggttctccct gccgccgaag
    11281 cggttgcacg aactcgccga ggccggcctg gaccacatcc agctgtccgt gcaggactcg
    11341 gccgcgatgc cggccgacgc catcgccgga cgtcgcgcgc acgcccgcaa gatgatcgtc
    11401 gcgcgcagca tcgccgaaac cggcttgccc atgaccgtca acgcggtcct gcaccgcggg
    11461 aacatcgcgc ggctgctcga catcgtcgaa ctcgcagcgg atttcggggc ggaacgcgtc
    11521 gagctggcca acacccagtt ctacggctgg gccttgcgca atcgcgccgc cctgatgccc
    11581 cgccgggagc aggtgcagcg cggggacgcg gacgcggcgc tggcccgcga gcgctacggc
    11641 gaccggttgg agatcgtgta cgtgaccgcg gactacttca gcccgcgccc caaaccgtgc
    11701 aactacggct ggggcagccg gcaactgacg gtggccccga acggcgacgt gctcccctgc
    11761 ctggccgccg ggcagctgcc cggcctggac gctccctcgg tgcgcgactc gacgctggag
    11821 gcggtctggt tcgattccgc ggcgttcaac cgcttccggg gcaccgagtg gatgcctgat
    11881 ccctgccgca gctgcgcgtt gaaggacgtc gacttcggcg gctgccgatg ccaggcctac
    11941 cagctcgtgg gcgacgcggc cgtcaccgat ccggcctgct cgttgtccga acaccacgac
    12001 ctgatccgga ccgagttcca accgcagccc gcagttccga ggcggatgtg atgcgggtac
    12061 gcgtcctcgg caccgcagcc ggcggcggcc ttccgcagtg gaactgcagc tgtcagagct
    12121 gctgccgggc cgcggaactc ggcgtgcagc tcagccagga ctgcctggcg atcagcggcg
    12181 acggaaactc ctggtacctg gtgaacgcgt cgccggacct gcgaactcag ctgctggcca
    12241 cccccgaact ccgtccaccg ccgggcaccc ggcgtacccc cgtcgaaggc gtgctgctca
    12301 ccagcgccga gctggaccac accctcggcc tgctcaccct gcgggaatcc tcccggctgc
    12361 cgatctacgc gaccgccgcc gtccaccagg cgcttcagca ggcattcccg atcaccgagg
    12421 tcgtcggcag ctacaccacc gtgcagccgg agatcgtctc cgatcgccaa gtgctggcgg
    12481 gcgggctcgc cgccgagatc gccgtcgtcg gcgacaagcg cccccgctac gcgggcgatc
    12541 tgcgcggaac cgattgggtc gtggcctacc ggttcaccgg ctccggccga agcctggtgt
    12601 acgcgccgtg cctgcccgcc tggaacgacg cgttcgagca ggtcatcgac ggcgccgacg
    12661 tcgtgctcct ggacggcacc ttcttcaccg aggacgagct gacgcatgcc tccggcagtg
    12721 accgccccgc gagcagcatg gggcacctgc cgatccgggc ggccctgccg gagatcgccc
    12781 gccacccgag gacgcggttc ctgttcaccc acctgaacaa caccaatccg ctggcgcacc
    12841 ccgacgcgcc ggagctcgcc gaggtgcgcg cggccggtgc cgagatcgcc gccgaacgcc
    12901 agctgctggt gctggaatga cgtccccgat ttttgttcgc gcctgatatc gggtatttgg
    12961 gagacgtgaa cgacgagcgg ctggcgaagt accgggagat gcgcgacttc acccgcaccg
    13021 ccgaacccag cggcgacggc gaggtgcgcg cgaccggcga ccgcttcgtc gtgcagcggc
    13081 accgggcccg ccgccggcac tacgacctgc ggctggagtt cgacggcgtc ctcctgagct
    13141 gggccgtgcc caagggcccg acgctggacc cgtcggcgcg gcgcatggcg gttcaggtcg
    13201 aggaccaccc cctggagtac gccgatttcg agggcaccat cccggccggc gagtacggcg
    13261 gcggcgacgt catcgtgtgg gaccgcggca cctgggaagc tgtggaggac gatccggccg
    13321 ccgcgatcga ggccgggacg ctgcacttcg acctgcatgg cgacaagctg gtgggccggt
    13381 tcgtgctggt gcggcgcggc gagaagcagt ggctgctgct gcacaagaag gacgaacacg
    13441 ccgagccggg ctggaatccg gaggatcatc cgcggtcggt gaagagcggc cgcaccaacg
    13501 aggaggtcgc cgccgcgccg gaagcgatgt ggcgcagcga tctaccgccg tcggaagccg
    13561 aaattccctt gggtgccaac aagtcccgcg cgaaggcgca ctgggatccg cccaccggcg
    13621 aggagctggc ggcgctcgac gagctcggca gcaagggccg atggcggctg gccgggcgga
    13681 acctcgcgct gaccaacctc gacaaggtgc tgttcccggc ccgcgacgac gaggcgccgg
    13741 tgaccaagcg cgacctgatc cgctaccacg cgctgatcgc cccagtgatg ctgccctacc
    13801 tcgccgaccg accgctgaac tcgcaccgct tcccgaacgg ggtggacgaa cccggtttct
    13861 ggcacaagga agtcccgagc cacgcccccg actggctccg ccgctggcgc tacgaggacg
    13921 ccgacccgga cgacacccag tggtacctca tcccggacag cgtccccgcc ctcgcctggc
    13981 tggccaacta cgcggcgctg gaactgcacg cgtggacctc gcgcgcatcc gacgtccacc
    14041 acccgacctg ggcgctgttc gacatcgacc cgggcagcag gacgacgttc gaggaagtgc
    14101 tcgtcctcgc tcgcctccac cggaccgcaa tggagcacct cggcgtcgag gcccgcccga
    14161 aggtgaccgg gcagcgcggc atccagatct gggtgccggt cgaaccgcgc tacacctacg
    14221 cggaaacccg ggcctgggtc gagaaggtgt ccaaggccgt cggcggcacc gtccccgagc
    14281 tggtcagctg ggcgtggacg aagaccgacc gccgcggcct ggcgcggctg gactacaccc
    14341 agaacgtcat caacaagacc ctggtcgccc cctacagcgc ccgcccgcgg ccgggcgccc
    14401 cggtgtccgt gccgctggag tgggacgagc tcgacgaccc ggacctggcc cccgaccggt
    14461 ggacgatccg caccgtcctg gaccggatcg caacggtcgg ggaccccttc gcggccctcc
    14521 tcgacgtcga gcagcagcta ccaccggtct gagccgtcgg cgaaccgcca cggcggcttc
    14581 caaggcgctc gctttctgcg ctccggttgc gacgtcctgc tcaccaggca gaagcaacgg
    14641 gcacgcggcc gcctcctcgg aagagtgatc gagctggcgc ggccgaccgg gtaccggttg
    14701 gctgttgatc atgcaaatcc gaacccgatc ggcagtgctc gccgctgccg ccctgctgtt
    14761 cctcgccccg gccgcgttcc cggccgcggc gcaggaatcc gcctcttccc gactgctggg
    14821 gacctacgtg gtgccgcacg acctgcgggt ggacggcacc ccggtcggcg gtctgtcctc
    14881 ggtggactac gaccgccgaa gcggcgactt catcttcgtc agcgacgact ggtccgacca
    14941 cgcaccggcc cgctactacc gggccgacgt ctcggtgacc gagcgcggcg tcgaggacgt
    15001 gacgttcacc ggggcgtcgt tgttccgccg cccggacggc accacctatc cggcgatcga
    15061 catctggcgc ggcgccgtgc agaagaagct gctggtcgac ctggacgaga tcggcgtgcc
    15121 ctacaccgac aacgtcgagg gcatcagctg gggaccgctc ctgcccaccg gggaacgggt
    15181 gctcctggtg gtcagcgaca acaacttctc gcccaaccag cagacccagc tgatcgccat
    15241 cgccgtccgc tgaccggcgg gcgtcgagcg ctggaacccg cgtcttcggt tcgtttcgag
    15301 gacgtcgctg tgaccgccaa gttcgcgaag aacggccgcc ggacgcggtt gatcagccga
    15361 ccttcatcgg tccgcctcct cggtggtgtg cgactaccag gtcacgggca gttcagtgac
    15421 gccgccggtg atggtggtgc gcacctccag ctcgtcgagg tccttggcca ggcgtaggcc
    15481 agggaggcgc tgggcgaggg tggcgaagac gatccggagt tcggtgcggg cgaggctggc
    15541 gccgatacag aagtgcgagc cgtgcccgaa cccgaggtgg gcgcgttcct cgcggtcggg
    15601 gtcgaaggtc tcggcgttcg agtaggcggc ctggtcccgg ttggcggcgt tgatggacag
    15661 gatgacggca tcgccgcggt ggatggtggt gcctgcgacg tcgaggtcgg tgtgggcgta
    15721 gcgcagcagg ccgaggtcgc ccggtgctcc taggcgcatg atctcctcga tggtggcgtt
    15781 gacccggccg gtggggtcgg cggtcaacga ctgccactga tcggggcggg tgagcagtaa
    15841 cagggtgccc agtccgatgc ggttgaccgt ggtctcgtgc ccggcaaaga gcagtccgac
    15901 gcacaggcgg accatctcgt cgtagtcgaa ccgctcgtcg gcgctctggg cgcgcacgat
    15961 gtcggagatg atgtcctcgc ccggctcggc gcgtttgccc tccgccaacc gtgccatgta
    16021 cttgccgaac tcggcccgcg cctggtgggc gtcgtccccg ctggcgtagc tggccatgcg
    16081 atcggatagt gaccggaagt gctcgcggtc gctctcgggc actcccagca gctggcagat
    16141 gaccgcgacc ggcagcggga aggccagccc ggcgtgcagg tcgacgatcc cgtcgggcgc
    16201 ggcgtcgtgc tcggcgacca gctggtcgat gtagtcgtcg accaggtctt gcatgtgacc
    16261 ggaaagcatc cgcatccgct tggccgagaa cgccggggtc agcagtcggc gcatccgcgc
    16321 gtggtcggct tcttcggtct cgtagttgcc cgtgggaccg tcctgcaccg cggcggtcgt
    16381 gatgcgcgat gcccgctccg gctcggggtg cgaccgcccg agtcgcttgt cgctgagcag
    16441 ctcgcggacc tcgtcgaagc gcgtgaccag ccaggcgggg tcaccggccg gggcggtgac
    16501 cggcgtgacc ggcgcttctc ggcgcagcac ctcgtacagc ggtgcgagat caagcacgtt
    16561 cggcctctcg aagggcaact gcaggcgctc ggcggcagcg ctcatggctt cctcctgtgg
    16621 tgtctcgcag ccgtggacca ctcctaaccc taccgattat tggcagtcac tgccaataat
    16681 gttgagtcgg ttagggtgtg ccaacgcgca accctcgatc tgccggtgga ggtgtccttg
    16741 gttgagcgac acgaccgcag gatccgccgc gggcgcccac cggtgagcga ccagcaacgc
    16801 caacagcaac ggctcgacat ctcccgccac gcagtaaggc tgttccgcga gcagggcgtg
    16861 gccgcgacat caggcgagca gatcgcaagg gccgccgggg tgtccgagcg cacgctgtgg
    16921 cgttacttcc gcagcaagga aagctgcgtc gaaccgctgc tgacgaagac gatcgacgcg
    16981 ttccaggagg tcctgcgcac ctggccgccc gaactggagc tggccgagca cctgcgcgcg
    17041 gcctacacgc ccgtgctcga ctcctccgac tccgacgtcg aggcggtgct cgccgtggtc
    17101 cgcatgacgc acgacgagcc cacgctgcgc gccgcctacc tcgtgctgcg ggagcgcgac
    17161 gagtccgcct tcgccgacgt actcgccgag cgcatgggca tgccgtccga cgcgctcgaa
    17221 gtccgcatgc aggccgccgc cacgagcgcg gcgctgcgcg cggcgaccga ccacctcgtt
    17281 tccattgcca ccgagggaat ttccccggaa accttcagcg aacatcgcga acgcctcgcc
    17341 gatgctctcc gcctcgtgac gtcctccgga cggctaaagc cgccggattc caaccagcaa
    17401 cgctagtcag tctcccccat cactgagatt cctggttcgc agacccgccc aacggttgga
    17461 ggtctccaca ggctgtcacc gcttgaagca cgtcggcttc tttccgtcca gcggcgagaa
    17521 tgttgcgggc cgcgttgacg tccgcgtgct cggaatatcc gcgagtggtg caccggatgc
    17581 gggcagccgg tcgagcggtg tccacatcgg atggttcggt gtgcgcggtg caggcccaag
    17641 gcccgtgagc gtttttcggt gctatggcac ccaaaatcac tcacggccag gtggcgacct
    17701 tcgccgcggc ggcgcgtggg gtcggtagcg gaaagtccgg ccgcgagcgt ccgcgacggc
    17761 gcccggcctg tcgcctgggc gcagccggcg atggcgggac gccccgaggg tgtcgaaacc
    17821 ctccggtcct aataccggcc cggcgctggt ggtcgtcggc gaggaggaca ccctgacgcc
    17881 gccggagaac gcgcgcgaac tcgcgggcgc gctgtcagga agcgagctcg tgacgctgcc
    17941 cggtgccggg cacctgccgt cgatcgagtc gccggacgca ttcgccgaag ccgtccgccc
    18001 ccggctttcc cggctcggct gagcgctagt tctcgcccgg tggtcgggca tcccgctcga
    18061 tgctgcgatc agacgacttc ttggcgtccg cttcggatcg cttggactgc tcggccgttt
    18121 cgccgggccg cacgaagtac gcgccggacg agaaacctac tgttggcaag gtaaccgctg
    18181 agcacgtcaa cagcagattc gacgcgctca ccccacagct aaagcaaggg gtctgcgcgc
    18241 gctacgtttg tccgatcacg cgggtgccca ctcgccgcta acagccctgt accagcgcct
    18301 caaagacggg tgcaccagtg cccgctgcct tgtccgcatc gccggtcagc tggtgtagga
    18361 gatgaatcca ccgacgaggg caccgtagag gacatgcccc agaagactga cgatcggtgt
    18421 caccactccg tagttgagca agaggaaacc cggcggttcg agcagcgcgc tctggggagc
    18481 gctggtcagg ttggttccca tccgcgggtg caccaccggc agcaggaggt tcaccagtgc
    18541 ggtgccagcg aacatgccgt ggaccagacc gaacagcgcc cccaaccacc aactgctggt
    18601 ccccagggcg acgaacagcc cgtagtagcc caaggcgaac agctccccga acacgaagtg
    18661 cgccaggtag ccgagggctt tcgctcggga gcggttgacc gttacgcagg tgccgagcag
    18721 gaaagggatg tcgatgcggg tcagtttgag ctcattcgcc gcacgcaatg ccgtggtcag
    18781 caccaaggtg ccgatgaacc cgccagcgag cgctccccag atcgtcaccg cgtcatcccc
    18841 tgctcggtga tcgcacaagc cgcgctgatc aacgccagat gggtcaggcc ctgcggcatg
    18901 tttcccagga actcccccgt gttcgggtcg atttcctcgc tgtagaggcc cacgtcgttg
    18961 gccagtccga ccagttggtc catcagctct gcggcctccc cgaggtggcc gcagcgagcc
    19021 agggcctcag ccagccagaa cgagcaggcc acaaacgccc cctcagtccc ttgcagacca
    19081 tcgtcaccgc cgtagcggta cacgaacggc ccgtgcgcca ggtcacggcg gatggcctcg
    19141 atcgtgccat gcatccgagg atgctgcgga ctcgcgtagc cgcgcagcag gccgagcaag
    19201 acgctgacgt ctacctcctc ggcgtcggcg ctgcgcacgt agctgttcag gttctcgctc
    19261 agacagcgcg tttcgatgaa atcctcgatc acggcctgct cccgtcgcca cgcgggtgcg
    19321 tgccgacggg agagcagccc gcgttcggcc aggcgcagcg cgcggtcgag agcgatccag
    19381 cacatcatct tcgactgggt gaaatgttgg ggcggactgc ggacttccca gatcccctcg
    19441 tccggttgcc gccagctcgc gcacacgaaa tcggccaccc ttgccaaccg ccgagcgatg
    19501 tcgggatcga gctggccgct ggccgtcgca tacagccagg ccgtctgcag aagttcgccg
    19561 taggtgtcca gctgcagctg ctcggctgcc gcattgccca cccgcaccgg cgccgacccg
    19621 cggtacccct ccaatgcgag cacccgctcg gatgctccga cccctccgtc gagccggtac
    19681 agcgggcgca ggcgcggctc gttgaactga gtggcatgca tcagccacca gaagtaggcc
    19741 tgcgcctcgc tggggcaccc gagtgtgaga agggcgtcca gtgtgaagac ggaatcccgc
    19801 agccaggaga accggtaatc ccagttgcgt tcgccgccga tctcctctgg aagcgacgag
    19861 gtcgcagcgg cggccaccgc gcccgacggg gcgtacacca gcagtttcag cgccaacgca
    19921 ctgcgcgtca cggctttctg ccatcgcccg gcgcaggcgc gatcccgaag ccaggcccgc
    19981 caacggtggc cggtctcctc cagccgcgcc gcgcactccg cgcgtgcggg caccaccagc
    20041 ggctcctcgt gcgcgaagct cagcgcgaga tccgcccgtg aacccagccg gatctcgaag
    20101 gcgccttcga tctcgtcacc ggcgcacagc ggctcgcccg caccccaggt gcacacggcc
    20161 agcgcgtctg tacctgccga cgccaccggc aagcctgctc gccggctgat acatgggctt
    20221 gcggcgccgt agccgaaacg gggctgcacg ctccagcgca tgggtactgc cccggacagt
    20281 ccttcgacct tgcggaccag ttcccgggtg ggcgtcaacg cccctccggg cagtgtcaaa
    20341 gcgtcggtca cccggaccgc gcccgcggcc gtggtaaacg tcgtctccac gacgttcgtg
    20401 ctcgggagat accggcggct cacctggtag ggcagctccg gttgcagggc gaaacagcct
    20461 ccccgacgag cgtcgagcac tgcgccgaag accgtaggcg agtccaggtc cggcatcgtc
    20521 agccagtcga ccgagccgtc ccgggcgagg agggcaacgg tgcgaccatc gcccaatgcc
    20581 gcgtactccc gcagcggcgc gtacccctcc cagcgaggcg cagcgacccg tgggccgttc
    20641 ccgagatcgg aaccgatcat cgtatcctcc gagccgctac caggagatcc cctcagccac
    20701 accaccggcc accaagatcg ttcaggtgac gcaggcccga gccgaccttc agatgacgaa
    20761 gctggtcacg ccgttgcaca gcacccttat ttcgccagac tgccgcagca cagcagagcc
    20821 gaaccaaggc ctttctgccc caatcacgga gcagcaggct gcgcgtcaag tcgggtcacc
    20881 cggaggcgac ctcgcccagt ccactttgga tgcgagcaaa acccagcggc tgcatcacgg
    20941 atcgccctgt tgaacgctgc cagcagcgcg acccggtacg caccagactg ccccgactcg
    21001 gtcgaggcgt tcgtcggggc agtcccaata gacaccgtgg tcacgggaaa acgaccgtgc
    21061 tgtggccgtt gagcagcacc cggcgttcgc agtgccagcg caccgcgcgg gacaacgcga
    21121 gcgcctcggc atcgcgaccc acagtttgca gtgcacgggg gtcgtaggtg tggtcgatcc
    21181 ggatgacttc ctgctcgatg atcggcccct cgtccaggtc cgaggtgacg taatgtgcgg
    21241 tggcaccgac gagtttgacg ccgcgctggt acgcctggtg gtacggcttg gcgcccttga
    21301 acccgggcag gaacgagtgg tggatgttga ttgcgcggcc gtacagagcc ttgctggtct
    21361 cgtccgagag gatctgcatg taccgcgcca gcacgaccag ctcggcgtcg tactcatcca
    21421 cgagctgcaa caggcgcgcc tcggcagcct ccttcgtcgc cggggtgacc ggaatgtgca
    21481 cgaacggcaa gccggcggcc tcggccatcg ggcgcaggtc ctggtggttg gacaccactg
    21541 cgacgatgtc acccccgaga cttccggccc gccaccggta gatcaggtcg ttcaggcagt
    21601 ggccgagctt cgatgccatc accaggatcc gggcgttccg gttggcgttg aagtcgtagg
    21661 tcatctcgaa ctcagcggcc accgtcgcga atccgcgcga cagctcctcc agatcggtgc
    21721 cgccgggtgc cgtgacctgg gtgcgcatga acagccggtc acgtacggcg tcgtcgaact
    21781 gctggtgctc accgatgtcg catccgtgtt cgaacaggta tccgctcacc gcgcgcacga
    21841 tgcctgtccg gttggggcag ctcagggtga gggtgcaggt gtgactcacg cagatctcct
    21901 cagcactcca cgatgttgag agccggcccg ccgcgggcgg tctcctggta cttgtccttc
    21961 atgcccgcgc cggtttcgcg catggtcttg atcgtcttgg cgagcatgat gtcgctgatg
    22021 cgaagcacgg tctccctcgt cagcgcaagc a
//
