LOCUS       NZ_CP040605            20972 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Saccharopolyspora sp. ASAGF58 chromosome, complete genome.
ACCESSION   NZ_CP040605
VERSION     NZ_CP040605.1
KEYWORDS    RefSeq.
SOURCE      Saccharopolyspora sp. ASAGF58
  ORGANISM  Saccharopolyspora sp. ASAGF58
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
REFERENCE   1  (bases 1 to 8045912)
  AUTHORS   Guo,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Grain Processing Research Group, Academy of
            National Food and Strategic Reserves Administration, Baiwanzhuang,
            Beijing 100037, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 76.15x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012277335.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:20:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,606
            CDSs (total)                      :: 7,535
            Genes (coding)                    :: 7,265
            CDSs (with protein)               :: 7,265
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 270
            CDSs (without protein)            :: 270
            Pseudo Genes (ambiguous residues) :: 0 of 270
            Pseudo Genes (frameshifted)       :: 80 of 270
            Pseudo Genes (incomplete)         :: 228 of 270
            Pseudo Genes (internal stop)      :: 14 of 270
            Pseudo Genes (multiple problems)  :: 48 of 270
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:54:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6529777
            Orig. end                         :: 6550749
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040605.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20972
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20972
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20972
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10972](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10972)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(215..700)
                     /locus_tag="FDZ84_RS30630"
                     /old_locus_tag="FDZ84_30765"
     CDS             complement(215..700)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223560.1"
                     /locus_tag="FDZ84_RS30630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30765"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_246868549.1"
                     /transl_table=11
                     /translation="MSVPAALSTRSGKYLLRRATADDLGPIVELLAADQLGATRESAAE
                     LEPYRRAFEAIDADPAHLLLVAATPGGQVVATMQLTFIPGLARRGALRAQIEAVRVHEQ
                     HRSHGLGREIFEWAIAESSGRGCTLVQLTTDKKRSDAHRFYDRLGFEASHEGYKLRL"
     misc_feature    complement(760..774)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     gene            834..1994
                     /locus_tag="FDZ84_RS30635"
                     /old_locus_tag="FDZ84_30770"
     CDS             834..1994
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692795.1"
                     /locus_tag="FDZ84_RS30635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30770"
                     /product="MFS transporter"
                     /protein_id="WP_246868550.1"
                     /transl_table=11
                     /translation="MPEVATDRRPVAARLAVATLFLVNGASFASVVPRYPELKDALSLS
                     NAALGTAIAALALGSLVAGLLAGPILVRWRSASVAVGCSVLLAADLVLIALAAQWWQLA
                     AALFFAGAMDAVVDVAMNAHGLRVQRRYRRSIVNSFHGMWSVGAIIGGLAGSLAAGAAL
                     PLPVHLGGAAVVLSAVAIISTRFLLPGHDDAERERRSRARPRFTLLLALLALGLLCAAA
                     ALVEDTAASWGAVYMRDSLGAAPVLAGLAFVALQAAQTVGRLSGDRLVDRFGNRAVARI
                     GGIMVLVGVGAALGWPSIPMTLVGFAVAGWGVATIIPAGFHAADELPGLSSGAGIAVVS
                     WVYRLGVLAVPPVVGLLADAVNLRVGLVIVPVAGGLIVLLASRLPR"
     gene            complement(2045..2212)
                     /locus_tag="FDZ84_RS30640"
     CDS             complement(2045..2212)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942195.1"
                     /locus_tag="FDZ84_RS30640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_168588710.1"
                     /transl_table=11
                     /translation="MRRGRRGHPCEPDTGRIGLWRCDECGQQWEIHGVADNPRIRKVSR
                     VGWFFAKLLG"
     gene            2360..2530
                     /locus_tag="FDZ84_RS30645"
     CDS             2360..2530
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692797.1"
                     /locus_tag="FDZ84_RS30645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_168584133.1"
                     /transl_table=11
                     /translation="MTVRELVEQMERRWEELMTLRASPDMYGSESLDGQLSELELWLLR
                     MHRLTAGTSAA"
     gene            complement(2597..4066)
                     /locus_tag="FDZ84_RS30650"
                     /old_locus_tag="FDZ84_30775"
     CDS             complement(2597..4066)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692798.1"
                     /locus_tag="FDZ84_RS30650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30775"
                     /product="MFS transporter"
                     /protein_id="WP_168588711.1"
                     /transl_table=11
                     /translation="MTTAVALRSQPGRWILVATILGSGVAFLDGSVVNVALPAIGRDIG
                     GDLSVLQWVLDAYLLTLSALLLLGGALGDRYGRRRVYVLGLVLFTLASLGCGLAPGGTA
                     LIVARLVQGVGGALLVPGSLALINSAIRHDDRGEAVGRWAGLTGMSSAIGPFAGGWLVD
                     AASWRWVFFINVPIAAAALLALRHVPESRNPAAAGRLDVYGAIAVTVGLAGAVYALIEI
                     PTKGLDAVSAGAAVVGVVALAAFPLIEMRHPDPLLPLSLFRSAQFTGANLTTFTVYAAL
                     SGALFLLSLQLQQSMGYPALAAGIATLPITIIMLLMSGRVGALAQRTGPRVPMTIGPLS
                     CAVGLALMTWAVPGSTYLSGVLPGVLVFGVGLSITVAPLTSAVLASVSPDNAGVASGVN
                     NAISRLAGLLAIAVLPVIAGLSHTGTGAPLGPGFGQAMLISAAMCAAGGVLAWLTIDRG
                     RKVDTYPLPGVNHACQDPCTCQLGKNRGQAT"
     gene            complement(4106..5368)
                     /locus_tag="FDZ84_RS30655"
                     /old_locus_tag="FDZ84_30780"
     CDS             complement(4106..5368)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692799.1"
                     /locus_tag="FDZ84_RS30655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30780"
                     /product="cytochrome P450"
                     /protein_id="WP_168588712.1"
                     /sec_met_domain="p450 (E-value: 6.2e-23, bitscore: 80.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAPAHVPDIFDPRRYADGVPHEDFAWLRRHAPVSWQEEHEIGDW
                     PAGPGFWAVTRYTDVVAVLKSAEVYSSWLGATQIRDPDPADLPFIRSMMLNLDPPEHGR
                     LRRLVSRAFTPRRIDRFRHEVAERARQLVDEVIERGECDLPVEVTDDYPLRNLADLLGV
                     PEPDQRMLLEWTNRVIGYQDPEHSEVTRGPDGKPVNPRSPTMLADMFSFAQDLAAFKRR
                     NPADDVMTALATAELDGRGLAGAELEMFFFLLSVAGNDTVRSALPGGMLAFAENPGQLR
                     LLRDDPGLLDSAVEEALRFHPPVLSFRRTATTDTELGGQRIAAGDKVVVFHCSAHFDEQ
                     QFPDPHCFDIRRTPNDHVAFGNGPHVCLGAHFARVQLRAFYHEALWRMRDLRVTGPVEH
                     LVSNFINGIKHLPVAFTPGSR"
     misc_feature    5439..5454
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.42"
                     /tool="antismash"
     misc_feature    complement(5440..5453)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.51"
                     /tool="antismash"
     misc_feature    5440..5454
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(5540..5554)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.4"
                     /tool="antismash"
     gene            5600..6361
                     /locus_tag="FDZ84_RS30660"
                     /old_locus_tag="FDZ84_30785"
     CDS             5600..6361
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942173.1"
                     /locus_tag="FDZ84_RS30660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30785"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_168588713.1"
                     /transl_table=11
                     /translation="MARAVPAVERAFDVLELFLDAHELSAPEITARLGLPRTTVHELVG
                     TLSERGYLMPAGSGSNRFRLGVRGFQLGAAYAERLDLAREGQLVAEDIAERCQETVHVG
                     VRDGADVLYVAKVDSSHPVRMVSAVGRRLPAHCTALGKALLAALPRAEVDELYGNRRLD
                     AMTEHSITTRKALRQEFDAIAKNGVAREYCESNESVACVAAPVRDQCGEVVAAMSIAVP
                     ILRWNDQTEVALRKLVHEGAAALSERLGHTG"
     misc_feature    complement(5622..5637)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.56"
                     /tool="antismash"
     gene            complement(6377..6811)
                     /locus_tag="FDZ84_RS30665"
                     /old_locus_tag="FDZ84_30790"
     CDS             complement(6377..6811)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692801.1"
                     /locus_tag="FDZ84_RS30665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30790"
                     /product="universal stress protein"
                     /protein_id="WP_168588714.1"
                     /transl_table=11
                     /translation="MNSGTQHKIVVGVDGSESSKCALRWALKQAALSGAAVHAVTSWEF
                     PAFYSWEGGPMPPDDFEESARKSLHDTVDEIEHEMSPPVPVERELAHGHAAQTLLDASE
                     GADLLVVGSRGHGSFYGALLGSVSQRCVQHAKCPVVIVRH"
     gene            complement(6850..7683)
                     /locus_tag="FDZ84_RS30670"
                     /old_locus_tag="FDZ84_30795"
     CDS             complement(6850..7683)
                     /NRPS_PKS="Domain: PKS_KR (8-95). E-value: 2.6e-08. Score:
                     25.9. Matches aSDomain:
                     nrpspksdomains_FDZ84_RS30670_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692802.1"
                     /locus_tag="FDZ84_RS30670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30795"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_168588715.1"
                     /transl_table=11
                     /translation="MRTPSQRCILVTGATSGLGRALAHQLAKTGSRVLIHGRSAELAEQ
                     TRAEIAAATGSDRLDVVLADLAELRQVERLANDVQLRCDQLDVLVNNAGIGSGPPGGGR
                     EESPDGIELRFAVNYLAGYHLTHLLQPLLLASAPARVVNVASAGQHPIDFDDPMMTENY
                     IGARAYAQSKLAQIMFTFDLAEQLRGHGVTVNALHPATYMNTAMVREAGVSPLGTIAEG
                     VEATMRLVADPGLDEVTGEYFHGTRACRALEQAYDEQDRTRLRELSGKLVERARG"
     aSDomain        complement(7399..7659)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FDZ84_RS30670_PKS_KR.1"
                     /evalue="2.60E-08"
                     /label="FDZ84_RS30670_PKS_KR.1"
                     /locus_tag="FDZ84_RS30670"
                     /protein_end="95"
                     /protein_start="8"
                     /score="25.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ILVTGATSGLGRALAHQLAKTGSRVLIHGRSAELAEQTRAEIAAA
                     TGSDRLDVVLADLAELRQVERLANDVQLRCDQLDVLVNNAGI"
     CDS_motif       complement(7579..7659)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FDZ84_RS30670_0001"
                     /evalue="5.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="FDZ84_RS30670"
                     /protein_end="35"
                     /protein_start="8"
                     /score="22.2"
                     /tool="antismash"
                     /translation="ILVTGATSGLGRALAHQLAKTGSRVLI"
     gene            7952..9118
                     /locus_tag="FDZ84_RS30675"
                     /old_locus_tag="FDZ84_30800"
     CDS             7952..9118
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942169.1"
                     /locus_tag="FDZ84_RS30675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30800"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_168588716.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.8e-44, bitscore:
                     151.0, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSEESSTGRYLVLLEDNSTIIGTRELTRLTGIRCANTADAAGA
                     APEELFRGAGGIVLHQLGIALISADPDQAAALERASRETSPIAAFEQERRVFAIGAEAQ
                     VEDGESTWGLQAVRADHAQPTGKGVRVAVLDTGLDLKHPDFADRDIVAGSFVEGQDVQD
                     GHGHGTHVIGTSCGPRTLQGGPGYGIASEASIYAGKVLGDDGSGTDGGILSGIEWAISN
                     GAAVVSMSLGAPTQPGEPFSAAFERVAQRAMERGTLVIAAAGNESQRSAGVVAPVGHPA
                     NCPSILAVGAIDPQLQIADFSCGTVDEIGQVDLVGPGVDVYSSWPGAERYRKLSGTSMA
                     TPHVAGVAALYAQQYPERAWGLWARLSQTARRLPLASTDVGAGVVQAP"
     gene            complement(9139..9459)
                     /locus_tag="FDZ84_RS30680"
                     /old_locus_tag="FDZ84_30805"
     CDS             complement(9139..9459)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692804.1"
                     /locus_tag="FDZ84_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30805"
                     /product="hypothetical protein"
                     /protein_id="WP_168588717.1"
                     /transl_table=11
                     /translation="MESGTPSRWQDVNATAEAIAQASGKLEWSARQARTPAEIAVAREA
                     LLAVTAAGARLARQLDLLASSYETPNAAEPSAVHVALDQAAAAAEDLGNCAKVAAQAID
                     DD"
     gene            complement(9598..9933)
                     /locus_tag="FDZ84_RS30685"
                     /old_locus_tag="FDZ84_30810"
     CDS             complement(9598..9933)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659576.1"
                     /locus_tag="FDZ84_RS30685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30810"
                     /product="plasmid stabilization protein"
                     /protein_id="WP_168588718.1"
                     /transl_table=11
                     /translation="MPQQSWTEKEERQYEHIKNQAMERGSSEDRAEEIAARTVNKNRAQ
                     AGESQQRSRTATQDIPPQRRGGLRSGSGSGPGGRTKQQLYADAQRADIKGRSRMTKAEL
                     ERALQRS"
     gene            complement(10001..10972)
                     /locus_tag="FDZ84_RS30690"
                     /old_locus_tag="FDZ84_30815"
     CDS             complement(10001..10972)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692806.1"
                     /locus_tag="FDZ84_RS30690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30815"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_168588719.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.9e-119,
                     bitscore: 395.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.5e-61,
                     bitscore: 206.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTGTWPRAAARRELDAAGVQPQLRPAYQRCRVLNAAHGRTYFLA
                     TRLLTPAQRPAVHALYGFARWVDDIVDDTDESRTVRDRQQAVDQLDDKLRAGLRAGNSE
                     HPILAALVDTAARHRIDPALFTDFMASMRMDLTVRSYATRAALDAYIHGSAAVIGLQLL
                     PVLGTVCPAGEAEPYAAVLGGAFQLTNFLRDVGEDLDRGRVYLPLEELAVFGVDRERLV
                     WCRKAGRPDLPVRRALADQVARTRSKYRAAEPGIALLASWSRPCVRTAFTLYGEILDRI
                     VESGYDVFGRRLAVSGPRRLAVAAGALGAVVAARLRSRRANV"
     gene            complement(11064..11696)
                     /locus_tag="FDZ84_RS30695"
                     /old_locus_tag="FDZ84_30820"
     CDS             complement(11064..11696)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692807.1"
                     /locus_tag="FDZ84_RS30695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30820"
                     /product="hypothetical protein"
                     /protein_id="WP_168588720.1"
                     /transl_table=11
                     /translation="MSRLESLARAFLRYLYEDDRFRPEVAGFFDSPAAEAAALQPSWAE
                     LAEVVRTLREQELIATSGTGQQGAPARAGLTGSGLICAGRHGGDIGSWARAQSVAVLDE
                     PPAPVVPAQPSPAPAPRPDFTGLTRVAKVVLLTLPTVHARYGDTAGIELIARRLREAAR
                     QDRPDPRRVRLLAYRLRSELATGSVSNTLGVVLLDGLDEALAESGLG"
     misc_feature    complement(11917..11931)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.64"
                     /tool="antismash"
     gene            complement(12071..12718)
                     /locus_tag="FDZ84_RS30700"
                     /old_locus_tag="FDZ84_30825"
     CDS             complement(12071..12718)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692808.1"
                     /locus_tag="FDZ84_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30825"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_168588721.1"
                     /transl_table=11
                     /translation="MSGNAGRANRRGRPGYDLGRLLDVSVRVFNERGYEGTSMEDLSRR
                     LGITKSAIYYHVSSKDELMRLSVNRALDALFAVTEEEGSTTGKAIDRLEHVVRRSIEVL
                     VDELPFVTLLLRVRGNTKVERQALTRRREFDQVVSDLVKQAEAEGSIRPDVDPALTSRL
                     LFGMVNSVIEWYKPSRGLRAAQLADAVTKIAFEGLRASADEHAPGASGSRAR"
     gene            complement(12732..14075)
                     /gene="paaK"
                     /locus_tag="FDZ84_RS30705"
                     /old_locus_tag="FDZ84_30830"
     CDS             complement(12732..14075)
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (84-347). E-value: 6.9e-22.
                     Score: 69.5. Matches aSDomain:
                     nrpspksdomains_FDZ84_RS30705_AMP-binding.1"
                     /codon_start=1
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692809.1"
                     /locus_tag="FDZ84_RS30705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30830"
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_168588722.1"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-25, bitscore:
                     86.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTGAPRRLGTAPDPADLDPAERYSADELAAVQLERLQRTLHH
                     AYENVPLYRSKFDAAGVRPEDCQSLADLAKFPHTTKQDLRDNYPFGLLAVPMEQVRRLH
                     ASSGTTGKPTVVGYTEQDLDAWADVVARSIRAAGGRPGHKVHISYGYGLFTGGLGAHYG
                     AERLGCTVIPASGGMTARQVQIIQDFRPEIIMVTPSYMLTLIDEFERQGIDPRSTSLEI
                     GIFGAEPWTEQMRQEIEERLDIDAVDIYGLSEVMGPGVANECVETKDGLHIWEDHFYPE
                     VIDPFTEEVLPDGTEGELVFTSLTKQAMPVIRYRTRDLTRLLPGTARPMRRMTKITGRS
                     DDMIILRGVNVYPTQIEELVLRIYGLSPHFQLVLTREGRMDRMTVRVEARTDCPGDRRD
                     PAGAELVRAIKDGVGISTEVTVVDPDTLERSVGKLRRLVDRRESGSTG"
     CDS_motif       complement(13005..13067)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FDZ84_RS30705_0001"
                     /evalue="7.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="FDZ84_RS30705"
                     /protein_end="357"
                     /protein_start="336"
                     /score="18.5"
                     /tool="antismash"
                     /translation="TGRSDDMIILRGVNVYPTQIE"
     aSDomain        complement(13035..13823)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FDZ84_RS30705_AMP-binding.1"
                     /evalue="6.90E-22"
                     /label="FDZ84_RS30705_AMP-binding.1"
                     /locus_tag="FDZ84_RS30705"
                     /protein_end="347"
                     /protein_start="84"
                     /score="69.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RDNYPFGLLAVPMEQVRRLHASSGTTGKPTVVGYTEQDLDAWADV
                     VARSIRAAGGRPGHKVHISYGYGLFTGGLGAHYGAERLGCTVIPASGGMTARQVQIIQD
                     FRPEIIMVTPSYMLTLIDEFERQGIDPRSTSLEIGIFGAEPWTEQMRQEIEERLDIDAV
                     DIYGLSEVMGPGVANECVETKDGLHIWEDHFYPEVIDPFTEEVLPDGTEGELVFTSLTK
                     QAMPVIRYRTRDLTRLLPGTARPMRRMTKITGRSDDMIILR"
     misc_feature    14175..14190
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(14251..14266)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            14376..16418
                     /gene="paaZ"
                     /locus_tag="FDZ84_RS30710"
                     /old_locus_tag="FDZ84_30840"
     CDS             14376..16418
                     /codon_start=1
                     /gene="paaZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR02278"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692811.1"
                     /locus_tag="FDZ84_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30840"
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="WP_168588723.1"
                     /sec_met_domain="TIGR02278 (E-value: 9.1e-304, bitscore:
                     1007.6, seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Aldedh (E-value: 4.3e-64, bitscore: 215.5,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALRSYVKGDWHAPSDNGVPLHDAVTGEEVARVSSAGIDMAAVL
                     AHGRSRGGPALAELTFHQRAALLKSLASHLREHREELYALSARTGATLGDSKFDIDGGI
                     GVLFGYSSKGRRELPNSTVYVDGAVEPLSKGGTFVGQHICTPLQGVAVQINAFNFPVWG
                     PLEKFAPAFLAGVPSLIKPASQTAYLTHRLVELMADSGLLPDGSLQLVCGSVGDLFEHL
                     TDQDLVSFTGSASTGQRLRAHPVVAANSVRFNVEADSLNCSILGPDAAPGTDEFDLFVK
                     QLVTEMTVKAGQKCTAIRRALVPANLIDEVVAAAKERLAKVVVGNPASPEVRMGALASL
                     EQREEVRRSLKALLEAGTLVHGDPGRVDVVDAEAERGAFLPPLLVRCDDPDQPQPHEVE
                     AFGPVSTVMPYETAAQAVELARRGKGSLAGSVVTADAEFAREVVLGAASRHGRMLVLNR
                     ENAKENTGHGSPLPALVHGGPGRAGGGEELGGVRGVLHHMQRTAVQADPATLTAITGQW
                     VGGTPRNITEKHPFRKHLGELRIGDTVVAGPRTVTLDDVEHFAEFTGDTFYAHTDEEAA
                     RANPFFDGRVAHGYLVVSFAAGLFVDPDPGPVLANYGLENLRFLTPTYPGDEITVTMTA
                     KQITPRVGAEYGEVRWDVDVTNQDGASVAKYDVLTLVAKRPGEQG"
     gene            16435..17388
                     /gene="paaA"
                     /locus_tag="FDZ84_RS30715"
                     /old_locus_tag="FDZ84_30845"
     CDS             16435..17388
                     /GO_function="GO:0097266 - phenylacetyl-CoA 1,2-epoxidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692812.1"
                     /locus_tag="FDZ84_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30845"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaA"
                     /protein_id="WP_168590461.1"
                     /transl_table=11
                     /translation="MDRLDDAELQQHFDERIVHDQRIEPRDWMPEGYRKTLVRQIAQHA
                     HSEIIGMQPEGNWLTRAPSLRRKAILLAKVQDEAGHGLYLYSAAETLGVDRSELTEKLI
                     ERRQKYSSIFNYPTLTFADIGVIGWLVDGAAICNQVPLCRSSFGPYARAMVRICKEESF
                     HQRQGYELLMTMMRGTTEQREMVQDATNRWWWPSLMMFGPPDGDSPNTQQSMAWRIKRH
                     TNDELRQKFVDMTVPQAEALGVTLPDPELRWNDERGHHDFGEPDWSEFKRVIAGNGPCN
                     EERLARRRAAHEQGQWVRDAAAAHAAKKAVREEVAR"
     gene            17385..17696
                     /gene="paaB"
                     /locus_tag="FDZ84_RS30720"
                     /old_locus_tag="FDZ84_30850"
     CDS             17385..17696
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692813.1"
                     /locus_tag="FDZ84_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30850"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaB"
                     /protein_id="WP_168588724.1"
                     /transl_table=11
                     /translation="MSPDAETGAPRSSWPLFEVFVRGKRGLNHVHVGSLHAADEQMALH
                     NARNLYTRRNEGVSIWVVRADAITASSPDEKDPFFAPSGDKVYRHPTFYRIPDNVPHI"
     gene            17707..18597
                     /gene="paaC"
                     /locus_tag="FDZ84_RS30725"
                     /old_locus_tag="FDZ84_30855"
     CDS             17707..18597
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332043.1"
                     /locus_tag="FDZ84_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30855"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="WP_168588725.1"
                     /transl_table=11
                     /translation="MSFDNAYQALTAAEPDGESRWAFGTGFDDPLSGVDTALPDGVDGV
                     AFARYCLMLGDDALIASQRLTEWVTYAPELEDELALANIALDLLGQARLLLARAGQADG
                     SGRGEDELAYFRDEREFRNVRLVEPPNGDFAHTIARLLVFSTWRLALFARLAESRDPVL
                     AAIAAKGVKELAYHREYTAQWMVRLGDGTEVSHVRMQQGLDAVWPRVDELFVPNATDQE
                     MVAVGVGTDPAQARAEFDDVLEQVVAAATLQRPEASALAGVAEQTGRDGIHTEHLGYLL
                     AEMQSLARAHPEAAW"
     gene            18591..19109
                     /gene="paaD"
                     /locus_tag="FDZ84_RS30730"
                     /old_locus_tag="FDZ84_30860"
     CDS             18591..19109
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439904.1"
                     /locus_tag="FDZ84_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30860"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaD"
                     /protein_id="WP_168588726.1"
                     /transl_table=11
                     /translation="MVTSTKPDLRHARAVAESVTDPELPVLTLADLGVLRGVELAGDGK
                     VIVSITPTYSGCPAMPEMRADLSNRLSEAGFTDVEVRTVLDPPWTTDWISTAGRQKLAE
                     YGIAPPGAAPQRAAGPVPLTLTSPRTRVRCPQCGSPDTEQVSRFGATACKALRRCRSCH
                     EPFEHIKEI"
     gene            19111..20229
                     /gene="paaE"
                     /locus_tag="FDZ84_RS30735"
                     /old_locus_tag="FDZ84_30865"
     CDS             19111..20229
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaE"
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009942153.1"
                     /locus_tag="FDZ84_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30865"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaE"
                     /protein_id="WP_168588727.1"
                     /transl_table=11
                     /translation="MVRPAPVDPPAAPAPARTGRRRTSFHPLRVSHVERLCEDAVAVSF
                     DVPPELAEDFAFKPGQSLTLRRRVDGREERRSYSICAPHGATPRIGVRHVPGGLFSSWL
                     VQEVRPGDEIEVLPPTGSFTPDLTTPERHVCIAAGSGITPVLSIAASVLRETDATVTLL
                     YGNRRSDTVMFADELADLKDRYPTRLELVHVLSREPRESELFTGRLDATKIRAMLSTVV
                     DADSVDQWWLCGPFGMVSDAQDVLRESGVVNGRIHQELFYVEDVPPEPARHEEPTVQGP
                     TSEVTVVLDGRSTPMSLPRDVPVLDAAQRVRPDLPFACKGGVCGTCRAKVTCGEVRMRR
                     NFALEESEVADGFVLTCQSLPTTDTVTVDFDA"
ORIGIN
        1 ccgagcgggc cgtcgacgcc gacgatccgg ccctcgcgga gcatggcgtc gatgcgttcc
       61 ggggcgagct taggtatccg gtcgacgagg tggtcccgga cggtggccca gtggccgtcg
      121 gcgggcagtc gcaaccggac ggggtccagg ccgtgccgct ggggcagcgg agacttgagc
      181 ttgcgtcgca tcgccccgcc agcgtaaccg gtgatcagag ccggagtttg tagccctcgt
      241 gcgaggcctc gaagccgagc cggtcgtaga agcggtgcgc gtcggagcgc ttcttgtcgg
      301 ttgtcagctg gaccagcgtg cagccgcgcc cgctagactc agcgatggcc cactcgaaaa
      361 tctcgcgccc gaggccgtgg ctgcggtgct gctcgtggac gcggaccgct tcgatctgcg
      421 cccgcaacgc gccccgccgg gccagcccgg ggatgaacgt cagctgcatc gtcgccacga
      481 cctggccgcc cggcgtcgcg gcgaccagca ggagatgcgc gggatcggcg tcgatcgcct
      541 cgaacgcccg ccggtagggc tccagctcgg ccgcggattc ccgggtcgcg ccgagctggt
      601 cggctgccag cagctcgacg atcggcccga ggtcgtcggc ggtcgcccgg cgcagcaagt
      661 atttcccgga ccgggtggac agcgcggccg gcacgctcac gaaacctcca ctgtggactc
      721 tagttcgaga tctgccgttg ccgaccctag cgtggcacat gaacacgaag acccggagcg
      781 cgagccggct ggcctttggc atgatcgtcg gggactccgg agaagggagg ggtatgcccg
      841 aagtcgcgac cgatcggcgg ccggtggcgg cgcggttggc ggtggccacg ctgttcctgg
      901 tcaacggcgc gagcttcgcc agcgtcgtgc cccgctaccc ggagctcaag gacgccctgt
      961 cgctgtccaa tgccgcgctg ggcaccgcga tcgccgcgct ggccctgggt tcgctggtcg
     1021 cgggactgct tgccgggccg atcctggtcc gatggcgctc ggcgagcgtc gcggtcggct
     1081 gttcggtgct gctggccgcc gatctcgtgc tgatcgcgtt ggcggcgcag tggtggcagc
     1141 tggctgcggc cctgttcttc gcgggcgcga tggacgcggt cgtggacgtg gcgatgaacg
     1201 cgcacgggct tcgggtgcag cggcgctacc ggcgatcgat cgtgaactcc ttccacggca
     1261 tgtggagcgt cggcgcgatc atcggcggcc tggcaggctc gttggcagcg ggagcggccc
     1321 taccgctgcc ggtgcatctc ggcggcgccg ccgtcgtgct gtccgccgtc gcgatcatct
     1381 ccacgcggtt cctgctgccc ggacatgacg acgccgagcg ggaaaggaga tcgcgagccc
     1441 ggccacgctt cacactgctg ctcgccctgc tggcgctggg cctgttgtgc gctgcggcgg
     1501 cgctggtcga ggacacggcg gcttcgtggg gcgcggtgta catgcgcgat tcgctgggcg
     1561 cggccccggt gttggcgggg ctggcgttcg tcgcgttgca ggccgcgcag acggtcggca
     1621 ggctctccgg cgaccggttg gtggaccgct tcggcaaccg ggcggtggcc cgcatcggcg
     1681 ggatcatggt gctcgtgggc gtcggtgcgg cgctcggctg gccgtccatc cccatgacgc
     1741 tggtcggatt cgcggtggcg ggctgggggg tcgccacgat catcccggcc gggttccacg
     1801 ccgcggacga actccccggc ctgtcctccg gtgccgggat cgcggtcgtc agctgggtct
     1861 accggctcgg ggtgctggcc gtgccgcccg tcgtcgggct gctcgccgat gcggtcaacc
     1921 tgcgcgtggg gctggtgatc gttccggtcg caggcgggct gatcgtgctg ctggcctcgc
     1981 gcctgccccg ctgacccgtc agggcagccg tccgccgccc tcgaccggcg agggcctctg
     2041 ccggtcagcc gagcagcttg gcgaagaacc agccgacccg gctgaccttg cggatcctcg
     2101 ggttgtcggc cacgccgtgg atctcccact gctgcccgca ctcgtcgcag cgccacaagc
     2161 cgatccggcc ggtgtcgggt tcgcaggggt ggcctcggcg ccctcgtctc atgcaccgat
     2221 gacaccacac gcggtgcccg cggtgacccg aatcggttcc ggaagatcgg gtgaaaccgt
     2281 gactttcggc cttaccgcgc gtgcccggca gccccgtacc gtcatcggcg gtgttgcacg
     2341 tcggggagag gggcgccagg tgacggtgcg ggagttggtc gagcagatgg aacggcgctg
     2401 ggaagagctg atgactctgc gcgcgagccc ggacatgtac ggcagcgaga gcctggacgg
     2461 ccagctctcc gagctggagc tgtggctgct gcggatgcac cgcctgaccg cggggacctc
     2521 cgccgcatga caggacttcc ggcggtgcgc ggggtccgga tcagctgagt ccattgagga
     2581 cagatcggtt gccgggtcag gtggcctggc cgcgattctt gccgagctgg caggtgcagg
     2641 ggtcctggca ggcgtggttg acacccggca gcggataggt gtcgaccttc cgcccgcggt
     2701 cgatcgtcag ccacgcaagc acaccgccgg cggcgcacat ggccgccgag atcagcatgg
     2761 cctggccgaa accggggccg agcggggcac ccgttccggt gtgcgacaac ccggcgatca
     2821 ccgggagcac cgcgattgcg agcagcccgg ccagacggga tatggcattg ttcacgcccg
     2881 aggcgacgcc ggcgttgtcc gggctgaccg aggcgagcac cgccgaggtc agcggcgcca
     2941 ccgtgatgga caggccgacc ccgaagacca ggacgcccgg caacacgccg ctcaggtacg
     3001 tgctgccggg caccgcccac gtcatcagcg ccaggccgac cgcgcagctg agcgggccga
     3061 tggtcatcgg cacgcgcggg ccggtgcgct gcgcgagagc acccacgcgg ccggacatca
     3121 gcagcatgat gatcgtgatc ggcaacgtcg cgatcccggc ggccagcgcg gggtagccca
     3181 tcgactgctg caactgcagg gacagcagga acaacgcacc gctcagtgcc gcatagacgg
     3241 tgaaggtcgt gaggttcgct ccggtgaact gcgcggagcg gaacaacgac agcggcagca
     3301 gcggatccgg gtggcgcatc tcgatcagcg ggaaggccgc cagtgcgacc acgcccacca
     3361 cggccgctcc cgcggagacc gcgtcaagcc ccttcgtcgg gatctcgatc agggcgtaca
     3421 cggcgccggc caggccgacg gtcacggcga tcgcgccgta gacgtccagg cgaccggccg
     3481 cagccgggtt tcggctctcc ggcacgtgcc gcagcgcgag cagcgccgct gccgcgatgg
     3541 ggacgttgat gaagaacacc caccgccagg acgccgcgtc caccagccag ccacccgcga
     3601 acggcccgat cgccgacgac atgccggtca acccggccca gcggccgacc gcctcgccgc
     3661 ggtcgtcgtg ccggatggcg gagttgatca gcgcgaggct accgggcacc agcaacgccc
     3721 caccgacgcc ttgcaccagg cgtgcgacga tcaatgccgt gccgccgggt gccaggccgc
     3781 agcccagcga cgccagggtg aacagcacca acccgagcac gtacacccgg cggcggccgt
     3841 agcggtcgcc gagcgccccg ccgagcagca acaacgcgct gagcgtgagc agataggcgt
     3901 ccagcaccca ctgcaggacg ctgaggtcac cgccgatgtc ccggccgatc gccggcaacg
     3961 cgacgttgac gaccgaaccg tcgagaaacg ccacaccgga accgaggatc gtggcgacga
     4021 ggatccagcg tcccggctgg gagcgcaggg caacagcggt ggtcaccgca cgaccataag
     4081 gcgcgtgcct agggcccgcc ctcgatcacc tgctacccgg cgtgaacgcc accggcaggt
     4141 gcttgatccc gttgatgaag ttcgatacca ggtgctcgac cggccccgtc acccgcagat
     4201 cgcgcatccg ccacagcgcc tcgtggtaga acgcccgcag ctgcacccgg gcgaaatgcg
     4261 cacccaggca cacgtgcggg ccgttgccga aggcgacgtg gtcgttgggc gtgcgccgga
     4321 tgtcgaagca gtgcgggtcg gggaactgct gctcgtcgaa atgtgccgag cagtggaaca
     4381 ccacgacctt gtccccggcg gcgattcgct gaccgcccag ctcggtgtcg gtggtcgcgg
     4441 tgcggcggaa gctgagcacc ggtgggtgga agcgcagcgc ctcctccacg gcggagtcca
     4501 gcaaccctgg atcgtcgcgc agcagccgca actggccggg gttctccgcg aaggcgagca
     4561 tcccgcccgg cagcgcgctg cgcacggtgt cgttgccggc caccgagagc aggaagaaga
     4621 acatctccag ctcggcgccg gccagcccgc gcccgtccag ctcggcggta gccagcgcgg
     4681 tcatcacgtc atcggcaggg ttgcggcgct tgaacgccgc gaggtcctgg gcgaaggaga
     4741 acatgtcggc cagcatcgtc ggcgagcgcg ggttgaccgg cttgccgtcc gggccgcggg
     4801 tcacctcgga gtgctccggg tcctggtagc cgatcacccg gttggtccac tccagcagca
     4861 tccgctggtc cggctccggc acaccgagca ggtcggcgag gttgcgcagc gggtagtcgt
     4921 cggtgacctc caccggcaga tcgcactcgc cgcgctcgat cacctcgtcg accagctggc
     4981 gggcccgctc ggcgacctcg tgccggaacc ggtcgatccg ccgcggtgtg aacgcgcggc
     5041 tgacgaggcg gcgcaaccgc ccgtgctccg gcgggtcgag gttgagcatc atgctgcgga
     5101 tgaacggcag gtccgccggg tcgggatcgc ggatctgcgt ggcgcccagc caggacgaat
     5161 agacctcggc ggacttcagc acggcgacga cgtcggtgta ccgggtgacc gcccagaacc
     5221 cgggcccggc cggccagtcg ccgatctcgt gctcctcctg ccagctcacc ggcgcgtgcc
     5281 ggcgcagcca agcgaagtcc tcgtgcggca cgccgtcggc gtacctgcgc ggatcgaaga
     5341 tgtccgggac gtgggcgggc gctgccatgg cgactccttc aacgtcttac ggccctggag
     5401 cctatagccg gatccgtttc gcgcggcagt gcaagcggtg gaacttccgt tcgatattcc
     5461 gcacaacgtt cgctggatcg tatggttggc cgggttgggt ggtcaagcgc ctgagctggt
     5521 gttggccgat accgggtacg atgttcggaa tatcggtcaa acagttggcc ggttgagatg
     5581 tgacaggggg agagaacgcg tggcacgagc ggtacctgcc gtggaacggg cattcgatgt
     5641 cctggagctg ttcctggacg cccacgagct gagcgccccg gagatcaccg cgcggctggg
     5701 cctgccgcgc accacggtgc acgagctggt cggcacgctc agcgagcgcg gctacctgat
     5761 gcccgcaggt agcggcagca accggttccg gctgggagta cgcggcttcc agctgggcgc
     5821 ggcctacgcc gagcggctgg acctagcccg tgagggccag ctcgtcgccg aggacatcgc
     5881 cgagcgctgc caggaaacgg tgcacgtcgg ggtgcgagac ggggcggacg tgctgtacgt
     5941 ggccaaggtc gacagcagcc acccggtgcg gatggtctcg gccgtgggcc ggcggctgcc
     6001 cgcgcactgc accgcgctcg gcaaggcgct gctggcggcg ctgccgcgcg cagaagtcga
     6061 cgagctctac ggcaaccgcc gcctggatgc gatgaccgag cacagcatca ccacccgcaa
     6121 ggcgctgcgc caagagttcg acgccatcgc caagaacggc gtggcacgcg agtactgcga
     6181 gtccaacgag tcggtggcct gcgttgcggc gccggtgcgc gaccagtgcg gcgaggtcgt
     6241 cgccgcgatg agcatcgcgg tgccgatcct gcgctggaac gaccagaccg aagtggcgct
     6301 gcgcaaactc gtccacgaag gcgcggccgc cctgtccgaa cgcctgggcc acaccggcta
     6361 ggccgccgcg ctacccctag tgccggacga tcaccaccgg gcatttcgcg tgttggacgc
     6421 agcgctggct caccgagccg agcagcgcgc cgtagaagct gccgtggccg cggctgccga
     6481 ccaccagcag gtcggcgccc tcggaggcgt ccagcagcgt ctgagccgcg tgcccatggg
     6541 cgagctcgcg ctccaccggc accggcgggc tcatctcgtg ctcgatctcg tcgacggtgt
     6601 cgtggaggct cttgcgcgcg gactcctcga agtcatccgg cggcatcggg ccaccctccc
     6661 agctgtagaa ggcggggaac tcccaggagg tgaccgcgtg caccgcggcc ccggaaagcg
     6721 ctgcctgctt cagcgcccac cgcagggcgc acttggacga ctccgagccg tccacgccga
     6781 cgacgatctt gtgctgggtt ccgctgttca tgacgccagc ctccagttcg acgatccgct
     6841 gtggcgggtt cagccgcggg cccgctcgac gagcttgccg gagagctctc gcagccgcgt
     6901 cctgtcctgc tcgtcgtagg cctgctcgag cgcgcggcac gcgcgggtcc catggaagta
     6961 ctccccggtg acctcgtcca gtcccggatc cgcgaccagc cgcatcgtcg cctcgacgcc
     7021 ttcggcgatc gtgcccagcg gactcacgcc ggcctcgcgg accatcgcgg tgttcatgta
     7081 ggtcgccggg tgcaacgcgt tgaccgtcac gccgtggccg cgaagctgtt cggccaggtc
     7141 gaaggtgaac atgatctgcg cgagcttgct ctgcgcgtac gcccgggcgc cgatgtagtt
     7201 ctcggtcatc atcgggtcgt cgaagtcgat cgggtgctga ccggccgagg cgacgttgac
     7261 cacccgggcc ggtgccgagg caagcagcag cggctgcagc aagtgcgtca ggtggtagcc
     7321 ggccaggtag ttcaccgcga accgcagttc gatgccgtcc gggctctcct cgcgcccgcc
     7381 gcccggcggc ccggaaccga tgcccgcgtt gttcaccagc acgtccagct ggtcgcagcg
     7441 cagctgcacg tcgttggcca gccgttcgac ctggcgcagc tcagcgaggt cggcgagcac
     7501 cacgtcgagg cggtcggagc cggtggccgc cgcgatctcc gcgcgcgttt gctcagctag
     7561 ctccgcgctg cgcccgtgta tcagtacccg ggacccggtc ttggcgagct ggtgggcaag
     7621 tgcccgtccg agcccgctgg tcgcgccggt gaccaggatg cagcgctggc tgggagtgcg
     7681 cacggtcgct ccgaactgtc gggaggtgat taccaccagt gtgcggatga gcttccgctg
     7741 ttgtcatcag cgcatgcgtg tcgtacctga tagcccccga cctgagtacc ccgaaagcgt
     7801 tgtgtcgcag gtatttcact gaggacatcg agaccggcgg cacagatcgt gcagtcctta
     7861 cccgagtggg cgcttgtaac tgtgggtaac gcgcgataca cctggggacg gtgtggcgcc
     7921 gctacacccg aaacctgccg agggagcgac catgaccacc agcgaggaga gctccaccgg
     7981 acgttatctg gtgctgctgg aagacaattc gacgatcatc ggaacccgcg agctgacgcg
     8041 gctgacgggc atccgctgcg ccaacaccgc cgacgcggcc ggcgcggcac cggaggagct
     8101 gttccgcggc gcgggcggga tcgtgctgca tcagctcggc atcgcgttga tcagcgccga
     8161 tccggaccag gccgcggcgc tcgaacgcgc gtcccgggag accagcccga tcgctgcgtt
     8221 cgagcaggag cgcagggtgt tcgccatcgg cgcggaggcg caggtggagg acggcgagtc
     8281 cacgtggggc ctgcaggcgg tgcgcgccga ccacgcgcag cccaccggca agggcgtccg
     8341 ggtcgcggtg ctcgacaccg gcctggacct caagcacccc gacttcgccg accgggacat
     8401 cgtcgccggg tccttcgtgg agggccagga cgtgcaggac ggccacgggc acggtacgca
     8461 cgtgatcggc acctcctgcg gtccgcggac cttgcagggc ggccccggct acggcatcgc
     8521 ttcggaggcc agtatctacg cgggcaaggt gctcggcgac gacggctccg gaaccgacgg
     8581 cggcatcctc tccggcatcg agtgggcaat ctccaacgga gccgccgtgg tgtcgatgtc
     8641 gctcggcgcg ccgacgcagc ccggcgaacc gttctccgcg gccttcgagc gggtcgccca
     8701 acgcgctatg gagcgcggca cgctggtcat cgccgcggcc ggcaacgaga gccagcgttc
     8761 cgccggggtg gtcgcgccgg tcggccaccc ggcgaactgc ccgtcgatcc tggcggtcgg
     8821 cgcgatcgac ccgcagctgc agatcgcgga cttctcctgc ggcaccgtcg acgagatcgg
     8881 ccaggtggat ctggtcggcc ccggcgtcga cgtctactcc agctggccgg gggcggagcg
     8941 ctaccgcaag ctcagcggca ccagcatggc caccccacac gtcgccggtg tcgcggcgct
     9001 gtacgcgcag cagtatccgg agcgagcgtg gggcctgtgg gcgcggctgt cgcagaccgc
     9061 acgccgactg ccgctcgcat cgaccgacgt cggtgcgggc gtggtccagg cgccgtagct
     9121 gccggggtcg ccgcgcggtc agtcatcatc gatggcctgc gcggcgacct tcgcgcagtt
     9181 gccgaggtct tcggcggcgg cggcggcctg atcgagcgcg acgtgcaccg ccgacggctc
     9241 ggcggcgttc ggcgtctcgt agctggaggc cagcaagtcg agctgccggg caagccgggc
     9301 cccggccgcg gtgacggcca gcaacgcttc ccgcgccacg gcgatttcgg ccggtgtcct
     9361 ggcttggcgg gcgctccatt ccaacttgcc gctggcctgc gcgatcgctt cggcggtcgc
     9421 gttgacgtcc tgccagcgcg acggcgttcc gctctccatc tggtcgcccc ccacaagcac
     9481 cggtattggc gcactatcag cagtttccgt ccctggtggg gcggttgaac cgggcccgcc
     9541 gccgcattca cccacccgaa cggcgggaac ccgcgttcgg cagctcggca ttcgcgctca
     9601 gctccgctgc agggcccgct ccagctccgc cttggtcatc ctcgaacggc ccttgatatc
     9661 ggcgcgctgc gcgtccgcgt agagctgttg cttggttcga ccgcccggcc cggagccgga
     9721 tccggagcgt agtccaccgc ggcgttgcgg ggggatgtcc tgcgtggcgg tcctgctccg
     9781 ctgctgggac tcaccggcct gcgcgcggtt cttgttgacc gtccgcgccg cgatctcttc
     9841 ggcgcggtcc tcgctgctgc cgcgctccat cgcctggttc ttgatgtgct cgtactgccg
     9901 ttcctctttc tcggtccagc tctgctgcgg cattcccacc cacctcgcct ccgcggtacg
     9961 tcggttgcga cgtgcttcgc gtacccggtg cgagcggcgg tcacacgttg gcgcgacggg
    10021 agcggaggcg cgccgcgacg accgcgccga gagcacctgc ggcgaccgcc aggcgccgcg
    10081 ggccggaaac agcgagccgt cgcccgaaca cgtcgtaccc ggactccacg atgcggtcga
    10141 ggatctcgcc gtacaacgtg aacgcggtgc gcacgcacgg ccgcgaccag gaggcgagca
    10201 gcgcgatgcc aggttccgcg gcccggtact tcgagcgggt gcgggcgacc tggtcggcga
    10261 gcgcccggcg caccgggagg tcgggccggc cggccttccg gcaccagacg agccgctccc
    10321 ggtcgacgcc gaacaccgcc agttcctcca gcggcaggta gacccggccg cggtcgaggt
    10381 cctcgccgac atcgcgcagg aagttggtga gctggaaagc gccgcccagc accgcggcgt
    10441 agggctcggc ctcgccggcc gggcataccg tgccgagcac cgggagcaac tggaggccga
    10501 tcaccgccgc cgagccgtgg atgtaggcgt ccagtgcagc ccgcgtcgcg tacgagcgga
    10561 cggtcaggtc catccgcatc gaggccatga agtcggtgaa cagcgccggg tcgatgcggt
    10621 gccgggcggc ggtgtcgacg agcgcggcaa ggatcgggtg ttcgctgtta ccggcgcgca
    10681 gaccggcgcg cagcttgtcg tccagctggt ccaccgcctg ctgccggtcc cggaccgttc
    10741 gcgactcgtc ggtgtcgtcg acgatgtcgt ccacccaccg cgcgaagccg tacagcgcgt
    10801 gcaccgcggg ccgctgcgcc ggggtcagca gccgggtcgc gaggaagtag gtgcggccgt
    10861 gcgcggcgtt gagcacccgg caccgctggt aggcgggacg cagctgcggc tggacgcccg
    10921 cggcgtcgag ctcgcggcgc gccgccgccc gcggccaggt gcccgtgtcc ataccgggaa
    10981 tctcagcaca cggagtgcgc gagcgtgcgc acggtgggca tccgcggtga acccggtcac
    11041 taccacagtc cgattaggac gtttcagccg agcccgctct cggcgagggc ctcgtcgagc
    11101 ccgtcgagca ggaccacgcc gagggtgttc gagaccgagc cggtcgccag ctcgctgcgg
    11161 agccggtagg cgagcaatcg cacccggcgc gggtccggcc ggtcctgccg cgcggcctcg
    11221 cgcagccgcc gtgcgatcaa ttcgatcccg gcggtgtcgc cgtagcgggc gtgcaccgtc
    11281 ggcagcgtga ggagcacgac cttggccacc cgggtcagcc cggtgaagtc gggtctgggc
    11341 gcgggtgccg gcgacggctg ggcgggcacc accggtgccg ggggctcgtc gagcaccgcg
    11401 accgactgcg ccctcgccca cgaaccgatg tccccgccgt gccggccggc gcagatcagc
    11461 ccggagccgg tcaggccggc gcgggcgggt gcgccctgct gcccggtccc gctggtggcg
    11521 atcagctcct gctcccgcag cgtccgcacg acttcggcga gctcggccca cgacggctgc
    11581 agcgccgcgg cctcggccgc cgggctgtcg aagaaacccg cgacctcggg ccggaatcgg
    11641 tcgtcctcgt agaggtagcg gaggaaggcg cgagcgagcg actcaagcct tgacacggtt
    11701 ggcctccaga ttgctcgtcc agggtgcagg gcgagaggga gggcggaccc gggtcctgcc
    11761 gaagaccgca gaacgcaccg gcgcgcagcc ggtttcggaa tcatggttgc cgctgtcccc
    11821 agtttcagcg gatccgccat gcgaccgccg ggtcgcggtc ggtcacatcg aaggagcgta
    11881 agcggacccc ggccgtgatc gcagtggtct tttgtcaccc acaagttggg gattgcgatg
    11941 ccggggcgta actgtccatt gtgctcaatg tcggcacaat ccgcaccact gcgcagaaag
    12001 gggctggagt gacgcgtggg accgccagcc gtcccgcatg gatgatcgtc atgacgggag
    12061 ttccggagat ttatcgcgcg cgagatccgg aagcgccggg cgcgtgctcg tcggcgctgg
    12121 cccgcagacc ctcgaaggcg atcttggtga ccgcgtcggc gagctgcgcg gcccgcaggc
    12181 cgcggctggg cttgtaccac tcgatgaccg agttgaccat gccgaacagc agccggctgg
    12241 tcagcgccgg gtcgacgtcc ggccggatgc tgccctccgc ctcggcctgc ttgacgaggt
    12301 cactgaccac ctggtcgaac tcgcggcgcc gggtcagcgc ctgccgctcg accttggtgt
    12361 tgccccgcac ccgcagcagc agcgtgacaa acggcagttc gtcgacgagc acctcgatgc
    12421 tgcgccggac cacatgctcc agccggtcga tggccttacc ggtggtcgac ccctcttcct
    12481 cggtgaccgc gaacagcgca tccagcgccc ggttgacgct cagccgcatc agctcgtcct
    12541 tgctggacac gtggtagtag atcgccgact tggtgatgcc cagccggcgg gagaggtcct
    12601 ccatgctggt gccctcgtag ccgcgctcgt tgaacacccg gacggagacg tccagcagcc
    12661 gaccgaggtc gtaacccggc cgaccccggc gattcgcgcg cccagcgttc cccgacatgg
    12721 ctcgcagtat ttcagccggt ggatccggat tcgcggcggt ccacgaggcg gcgcagcttg
    12781 ccaaccgaac gctccagcgt gtccggatcc accacggtga cctcggtgct gatgccgacg
    12841 ccgtccttga tcgcgcggac cagctcggcg ccggccggat cccggcggtc gcccgggcag
    12901 tcggtgcggg cctccacccg aaccgtcatc cggtccatcc ggccctcgcg ggtgagcacc
    12961 agctggaaat gcggcgacag gccgtagatg cgcagcacca gctcctcgat ctgggtgggg
    13021 tagacgttga cgccccgcag gatgatcatg tcgtcgctgc ggccggtgat cttggtcatc
    13081 cgccgcatcg gccgggccgt gccgggcagc agacgggtca ggtcccgggt gcggtagcgg
    13141 atgaccggca tggcctgctt ggtcagcgag gtgaacacga gttcgccctc ggtgccgtcg
    13201 ggcagcactt cctcggtgaa cgggtcgatc acctcggggt agaagtggtc ctcccagatg
    13261 tgcagcccgt ccttggtctc cacgcattcg ttggccacgc cggggcccat cacctcggac
    13321 aggccgtaga tgtcgaccgc gtcgatgtcc agccgttcct cgatctcctg ccgcatctgc
    13381 tcggtccacg gctcggcccc gaagatgccg atctcgagcg aggtgctgcg cgggtcgatg
    13441 ccctgccgtt cgaactcgtc gatgagggtg agcatgtagg acggggtgac catgatgatc
    13501 tcgggccgga agtcctggat gatctgcacc tgccgggcgg tcatcccccc ggaggccggg
    13561 atgacggtgc acccgagccg ctcggccccg tagtgcgcgc cgagcccgcc ggtgaacaag
    13621 ccgtacccgt aggagatgtg caccttgtgg cccggccgcc cgcctgcggc gcggatggag
    13681 cgcgccacca catcggccca ggcgtccagg tcctgctcgg tgtagccgac gacggtcggc
    13741 ttgcccgtgg tgccactgga ggcgtgcagc cgccggacct gctccatcgg cacggcgagc
    13801 aggccgaacg ggtagttgtc ccgcaggtcc tgcttggtgg tgtgcgggaa cttcgccagg
    13861 tcggccaagc tctggcagtc ctccggccgg acgcccgccg cgtcgaactt gctgcggtac
    13921 agcggcacgt tctcgtaggc gtggtgcagg gtccgctgca ggcgttccag ctgcaccgcg
    13981 gcgagttcgt cggcggagta ccgctcggcg gggtcgaggt cggccggatc cggcgcggtt
    14041 ccgagccggc gcggcgcgcc cgtcgtcgct gtcatgcttt aactccttcg ggctcccagc
    14101 gcctgcgagg ctcggtcgtc gtcgaacatg gcctgggccg ggttgcgcgt cgccgcgccg
    14161 ggctcctgca ctgggtcacc gcctcgtcac cgagcgaaca gtcggtaatt aatcctgcgc
    14221 cgcaggatcc tgtcaagggt tcccggcgaa gccggtccag acctggctcg gtaaagcaga
    14281 atttagctgc atcgggtggt gcgcgacagt cttgacgagt gctacttttt cgaacgaacg
    14341 gtcagttaaa gaaccagccg gaggaggtcg ggcgaatggc tgccctgcgg agctacgtca
    14401 agggcgactg gcacgcgccg tcggacaacg gggtgccgtt gcacgatgcg gtgaccggtg
    14461 aggaggtcgc gcgggtctcc tcggcgggga tcgacatggc cgcggtgctg gcgcacgggc
    14521 gcagccgggg cggcccggcg ctggcggagc tgacgttcca ccagcgtgcc gcgctgctga
    14581 agagcctcgc ctcgcacctg cgcgagcacc gcgaggagct gtacgcgctg tcggcccgca
    14641 ccggtgccac gctcggcgac tccaagttcg acatcgacgg cggcatcggg gtgctgttcg
    14701 gctactccag caagggccgc cgggaactgc ccaacagcac ggtctacgtc gacggcgcgg
    14761 tcgagccgct gagcaagggc ggcacgttcg tcgggcagca catctgcacg ccgctgcagg
    14821 gcgtcgcggt gcagatcaac gcgttcaact tcccggtgtg gggaccgctg gagaagttcg
    14881 cgcccgcctt cctggccggg gttcccagct tgatcaaacc ggccagccag accgcgtacc
    14941 tcacgcaccg gctggtggag ctgatggccg actccgggct actgccggac ggctcgctgc
    15001 agctggtctg cggcagcgtc ggcgacctgt tcgagcacct gaccgaccag gacctggtgt
    15061 cgttcaccgg ctcggcctcg accggccagc ggttgcgcgc ccacccggtg gtggcggcga
    15121 actcggtgcg gttcaacgtc gaggccgact cgctgaactg ctcgatcctg ggcccggacg
    15181 ccgcgccggg caccgacgag ttcgacctct tcgtcaagca gctggtcacc gagatgacgg
    15241 tcaaggccgg gcagaagtgc accgcgatcc ggcgggcgct ggtgccggcg aacctgatcg
    15301 acgaagtggt cgcggccgcc aaggagcggt tggcgaaggt agtcgtcggc aaccccgcct
    15361 cgccggaggt ccggatgggg gcgctggcca gcctggagca gcgcgaggag gtgcggcggt
    15421 cgctgaaggc gctgctggag gccggaacgc tggtgcacgg agaccccggg cgggtcgacg
    15481 tcgtggacgc cgaggcggag cgcggcgcgt tcctgccgcc gctgctggtc cgctgcgacg
    15541 acccagacca gccgcagccg cacgaggtcg aggccttcgg cccggtcagc acggtgatgc
    15601 cgtacgagac cgcggcgcag gccgtggagc tggcgcgccg cggcaagggc agcctcgccg
    15661 gttccgtggt gaccgccgac gcggaattcg cgcgcgaggt ggtgctgggc gcggcatcgc
    15721 ggcacggccg gatgctggtg ctcaaccgcg agaacgcgaa ggagaacacc gggcacggtt
    15781 cgccgctgcc cgcactggtc cacggcgggc cgggccgggc cggtggcggc gaggagctgg
    15841 gcggcgtccg cggcgtgctg caccacatgc agcggaccgc ggtgcaggcc gacccggcga
    15901 cgctgaccgc gatcaccggg cagtgggtgg gcggaactcc gcgcaacatc accgaaaagc
    15961 acccgttccg caagcatctc ggcgaactgc gcatcggtga cacggtggtc gccgggccgc
    16021 gcaccgtgac gctggacgac gtcgagcact tcgccgagtt caccggcgac accttttacg
    16081 cgcacaccga cgaggaagcg gcgcgggcca atccgttctt cgacggccgc gtggcgcacg
    16141 gctacctggt ggtgtccttc gccgccgggc tgttcgtgga tcccgacccg ggaccggtgc
    16201 tggccaacta cggcctggag aacctccggt tcctcacgcc gacctacccc ggtgacgaga
    16261 tcaccgtgac catgaccgct aagcagatca ctccgcgggt cggcgccgag tacggcgagg
    16321 tccgctggga cgtggacgtg accaaccagg acggcgcctc ggtggcgaag tacgacgtgc
    16381 tgacgctggt ggccaagcgg ccgggggagc aggggtgacc aggtgacgac cacggtggac
    16441 cggctcgacg acgccgagct gcagcagcac ttcgacgagc ggatcgtgca cgaccagcgc
    16501 atcgagccgc gggactggat gcccgagggc taccgcaaga ccctcgtgcg gcagatcgcc
    16561 cagcacgcgc actccgagat catcggcatg cagccggagg gcaactggct gacccgcgcc
    16621 ccgagcctgc ggcgcaaggc gatcctgctc gcgaaggtgc aggacgaggc ggggcacggg
    16681 ctctacctgt actccgcggc cgaaactctc ggagtggacc gttcggagct gaccgagaag
    16741 ctcatcgagc ggcggcagaa gtactcatcg atcttcaact acccgacgct gaccttcgcc
    16801 gacatcggcg tcatcgggtg gctggtcgac ggggcggcga tctgcaacca ggtgccgctg
    16861 tgccgcagct ccttcggtcc ttacgcgcgg gccatggtgc ggatctgcaa ggaggaatcg
    16921 ttccaccagc ggcagggcta cgagctgctg atgacgatga tgcgcggcac cacggagcag
    16981 cgggagatgg tgcaggacgc gacgaaccgc tggtggtggc cgtcgctgat gatgttcggc
    17041 ccaccggacg gcgactcgcc caacacccag cagtccatgg cgtggcggat caagcggcac
    17101 accaacgacg agctccggca gaagttcgtc gacatgaccg tgccgcaggc cgaggcgctc
    17161 ggcgtcacgc tgcccgaccc ggagctgcgc tggaacgacg agcgcgggca ccacgacttc
    17221 ggcgagccgg actggtccga gttcaagcgg gtcatcgccg gcaacgggcc ctgcaacgag
    17281 gagcggctgg cccggcgccg ggccgcgcac gagcaagggc agtgggtgcg cgacgcggca
    17341 gcggcccacg ctgccaaaaa ggccgtacgg gaggaggtcg cgcgatgagt ccggacgccg
    17401 agaccggcgc accgcggtcc tcgtggccgc tgttcgaggt tttcgtccgc ggcaagcggg
    17461 gtctgaacca cgtgcacgtg ggctcgctgc acgccgcgga cgagcagatg gcgctgcaca
    17521 acgcccgcaa cctctacacc cgccgcaacg agggcgtgag catctgggtg gtccgagcgg
    17581 acgcgatcac cgcgtccagc ccggacgaga aggacccgtt cttcgcaccc agcggcgaca
    17641 aggtgtacag gcacccgacg ttctaccgga tccccgacaa cgttccgcac atttgaggtc
    17701 atcccgatgt cgttcgacaa cgcctaccag gcgctgaccg ccgcggagcc cgacggcgag
    17761 tcccgctggg ccttcggcac cggcttcgac gatccgctgt ccggagtgga caccgcgctg
    17821 ccggacggcg tggacggcgt cgcgttcgcc cggtactgcc tgatgctcgg cgacgacgca
    17881 ctgatcgcct cgcaacggct gaccgagtgg gtcacctacg cgccggagct ggaggacgag
    17941 ctggcgctgg ccaacatcgc gctcgacctg ctgggccagg cacggctgct gctggcccgc
    18001 gccgggcagg ccgacggcag cgggcgcggc gaggacgagc tggcgtactt ccgcgacgaa
    18061 cgggagttcc gcaacgtgcg gctggtcgag ccgcccaacg gcgacttcgc gcacaccatc
    18121 gcccggctgc tggttttctc gacgtggcgc ctcgcgctgt tcgcccggct cgccgaatcg
    18181 cgcgacccgg tgctggcggc gatcgcggcc aagggggtca aggagttggc ttaccaccgc
    18241 gagtacacgg cacagtggat ggtccggctc ggtgacggca ccgaggtgtc ccatgtgcgg
    18301 atgcagcagg ggctcgacgc ggtgtggccg cgggtcgacg aactgttcgt gccgaacgcg
    18361 accgaccagg agatggtcgc ggtcggcgtc ggcaccgacc cggcacaggc gcgtgccgag
    18421 ttcgacgacg tcctggagca ggtcgtcgcg gcggccacct tgcagcggcc cgaggcttcg
    18481 gcgctggccg gggtggccga gcagaccggc cgggacggca tccacaccga gcacctgggc
    18541 tacctgctcg cggagatgca gagcctggcc cgagcgcacc cggaggcggc atggtgacga
    18601 gcacgaagcc ggacctccgg cacgcccggg cggttgccga gtcggtcacc gacccggagc
    18661 tgccggtgct gacgctggcc gacctcgggg tcctgcgcgg cgtcgagctc gccggagacg
    18721 ggaaggtcat cgtgtcgatc acgcccacct actcgggctg cccggcgatg cccgagatgc
    18781 gcgcggacct cagcaatcgg ctgagcgagg ccggtttcac cgacgtcgag gtgcgcaccg
    18841 tgctggaccc gccgtggacc accgactgga tcagcacggc agggcggcag aagctcgccg
    18901 agtacggcat cgccccgccg ggggccgctc cgcagcgcgc cgccggcccg gtgccgctga
    18961 cgctgacctc gccgcggacc cgggtccgct gcccgcagtg cggttcgcca gacaccgagc
    19021 aggtctcgcg gttcggcgcg accgcgtgta aggcgctgcg ccgatgccgc tcgtgccacg
    19081 aaccgttcga gcacatcaag gagatctgac gtggtccgtc ccgcccccgt cgacccaccc
    19141 gcggcccccg caccggcgcg gaccggccgt cgccgcacgt cgttccaccc gctgcgggtc
    19201 agccacgtgg agcggctgtg cgaggacgcg gtcgccgtca gcttcgacgt cccaccggag
    19261 ctcgccgagg atttcgcctt caagccgggc caatcgctga cgctgcgccg ccgggtcgac
    19321 ggccgcgagg agcgccggtc gtactcgatc tgcgccccac acggcgcaac accccggatc
    19381 ggcgtgcgcc acgtgccggg cgggttgttc tccagctggc tggtgcagga ggtgcggccc
    19441 ggcgacgaga tcgaagtgct gccgccgacg ggcagcttca ccccagacct gaccacaccc
    19501 gagcggcacg tgtgcatcgc cgccggatcg gggatcacgc ccgtgctgtc catcgcggca
    19561 tcggtgctgc gcgagacgga cgcgaccgtc acgttgctct acggcaaccg gcgcagcgac
    19621 acagtgatgt tcgccgacga gctcgccgac ctgaaggacc gctacccgac gcggctggag
    19681 ctggtgcacg tgctttcgcg ggaaccgcgc gagtcggagc tgttcaccgg ccggttggac
    19741 gcgacgaaga tccgggcgat gctatccacg gtggtcgacg ccgactcggt ggaccagtgg
    19801 tggttgtgcg ggccgttcgg catggtcagc gacgcgcagg acgtgctgcg cgaaagcggc
    19861 gtcgtcaacg gacgaatcca ccaggagctg ttctacgtcg aggacgtgcc gccggaaccg
    19921 gcgcgccacg aggagccgac ggtgcagggg ccgacgagcg aggtcacggt ggtgctcgac
    19981 ggccgttcga cgccgatgtc gctgccccgc gacgtcccgg tcctggacgc ggcccaacgg
    20041 gtccgccccg acctgccgtt cgcctgcaag ggcggcgtct gcggcacctg ccgggcgaag
    20101 gtcacctgcg gcgaagtccg catgcgccgc aacttcgccc tggaggaatc ggaagtggcg
    20161 gacgggttcg tcctcacctg ccaatcgctc ccgaccaccg acacggtcac ggtcgacttc
    20221 gacgcctgat caatcaggag gccttgcggg agcgggagcg gcggccttcg gtgccggtgg
    20281 gcttctccgt cgcctcggcg accgccttct cgagttcggc ccgcttcaac ctggtgcggc
    20341 ccttgatgcc cagccgcttg gcccggtcgt cgagctcggc cttgctcagc tcggacaggt
    20401 cctcctcgga tcgcgcgggc ttgcggccct tgcgcgcctc gtcgacgctg cgccgcagcg
    20461 cctcggtcag gtcggtgacg tccgtcggct tcggcggttc ctccgccgcc accacctcgc
    20521 cgccgcgcgc cttctccgcc agcagctcct cgaccttcgc ggtgtaggtg tcctcgtatt
    20581 gctccggttc ccacggcccg ctcatcgact cgatgatcgt ggtcgccatc tgcagttcct
    20641 tctccgacgg cttcgcctgc tcgccgtcct ctccgaccag ttcgctcgga tcgcggactt
    20701 cgtcggcgaa gaacagggtg ttcagcgcaa gcacgttgtc gtcggcgcgc accgccgtga
    20761 ggtactgctt gccccgcagc acgaaggtcg cgattcccgc ttggctggtt tcgtgcatcg
    20821 cccggcgcag caggttgtag ggccggaagt gctccttgct gttgggagcc agccagtagg
    20881 tcttctggaa gtgcacgggg tcgatctcgg tgatgtcgac gaaggtggtg atgtcgatgg
    20941 tgcgggaacg gccgggggcg atctcgtcga gt
//
