LOCUS       NZ_CP040605            20282 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Saccharopolyspora sp. ASAGF58 chromosome, complete genome.
ACCESSION   NZ_CP040605
VERSION     NZ_CP040605.1
KEYWORDS    RefSeq.
SOURCE      Saccharopolyspora sp. ASAGF58
  ORGANISM  Saccharopolyspora sp. ASAGF58
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
REFERENCE   1  (bases 1 to 8045912)
  AUTHORS   Guo,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Grain Processing Research Group, Academy of
            National Food and Strategic Reserves Administration, Baiwanzhuang,
            Beijing 100037, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 76.15x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012277335.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:20:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,606
            CDSs (total)                      :: 7,535
            Genes (coding)                    :: 7,265
            CDSs (with protein)               :: 7,265
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 270
            CDSs (without protein)            :: 270
            Pseudo Genes (ambiguous residues) :: 0 of 270
            Pseudo Genes (frameshifted)       :: 80 of 270
            Pseudo Genes (incomplete)         :: 228 of 270
            Pseudo Genes (internal stop)      :: 14 of 270
            Pseudo Genes (multiple problems)  :: 48 of 270
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:54:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6490307
            Orig. end                         :: 6510589
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040605.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20282
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="23"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20282
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20282
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10282](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10282)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            336..488
                     /locus_tag="FDZ84_RS39565"
     CDS             336..488
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS39565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="WP_246868547.1"
                     /transl_table=11
                     /translation="MAAVVLVLENRQTVEIRIFVPLVTMPMWTALAVMLVVGIVVGLLV
                     SRPRK"
     gene            complement(525..917)
                     /locus_tag="FDZ84_RS30445"
                     /old_locus_tag="FDZ84_30580"
     CDS             complement(525..917)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FDZ84_30580"
                     /product="hypothetical protein"
                     /protein_id="WP_168588674.1"
                     /transl_table=11
                     /translation="MPEHEHPLEALHRGRDAVAESVSLQARTPQPSLNELHAFGSAIVG
                     TLAELSQLSSVLAEQVGRFDEQDVERAKTSNHPGDKLRLAGTHLATLSAELAVAVTDAT
                     RYWTAIESVDLHTSGDLRPRRHPEAQ"
     gene            complement(1085..2020)
                     /locus_tag="FDZ84_RS30450"
                     /old_locus_tag="FDZ84_30585"
     CDS             complement(1085..2020)
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta9_cd03505"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692748.1"
                     /locus_tag="FDZ84_RS30450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30585"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_168588675.1"
                     /sec_met_domain="delta9_cd03505 (E-value: 5.1e-104,
                     bitscore: 348.3, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVASDVSKSNPQPLLAGRRPLAPHLSVYAFILVPFLALIAAVPLV
                     WGWGLRWWDALLAVGWYVFTILGVTVGYHRYFTHGAFRAKRWMRIALAVAGSMAVQGPI
                     LHWVADHRRHHAFADREGDPHSPWAFGTSPVALARGFWHAHMGWIFDRDLTNQQRFAPD
                     LLADPDIRLVHRLFGPLTVATFALPALCGGLITGTWWGAATSFFWAGLVRVAFLHHVTW
                     SVNSICHMFGERPFRSRDKAANFWPLALLSMGESWHNLHHADPTCARHGVRPGQIDISA
                     RLIRIFEKLGWVTHVRWPTARRLARLSVDD"
     gene            complement(2207..3688)
                     /locus_tag="FDZ84_RS30455"
                     /old_locus_tag="FDZ84_30590"
     CDS             complement(2207..3688)
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010316408.1"
                     /locus_tag="FDZ84_RS30455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30590"
                     /product="diguanylate cyclase"
                     /protein_id="WP_168588676.1"
                     /transl_table=11
                     /translation="MRENDPLMAGLVPEPDRHVRMLLESGRPNAAGLAFRRLVADGANH
                     VDGRWDSSVVLVHRAYLAWRLDRIPLALDLVAEGWTVLDVDRPQGGSAAQAMGMLGDLL
                     QAVGHHDAARELITQSVQVARRCGAPEILAHCLEREANCWQLRAMEANGAADECFRTAL
                     ELFDEALSLASPGQIRNRVQAGSARALAALGHVAEAESRAVQALTASEEAEDRYTSAIA
                     NWVLAEIRRHQHRLAEARTFASRAVETAEWIRDTRLRTRFSLALTTICRELDDPVGEAA
                     ALRSLVAASRTAMRVLQVGLGQALEQRRVAIQAQRQESAAQQDACRDPLTGLLNRRGVE
                     HRASAADQAAVRWLVVMDVDNFKKINDAAGHTAGDAVLQEVARLLRRECRSDDLVCRWA
                     GDEFLVLLADREQAPGPGGPELAERIRAAVETHDWTPQVGSRTRPPTVSVGVAIGPTHF
                     VPLFAAADRALYRAKHAGRNRVEVESDRAFPPAQT"
     gene            complement(3775..5121)
                     /locus_tag="FDZ84_RS30460"
                     /old_locus_tag="FDZ84_30595"
     CDS             complement(3775..5121)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022743.5"
                     /locus_tag="FDZ84_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30595"
                     /product="DUF3100 domain-containing protein"
                     /protein_id="WP_168588677.1"
                     /transl_table=11
                     /translation="MTISTAPAEAGTKQTLPIAALALVIALVVQFVGQVKIDLGIGSII
                     IFPMVWGLVLGLLVSVQRFKPLGLDLQKAASALVGVAVMLLVARLAFNIGPSLPTLVKA
                     GPALLLQEVGHLLGTIALALPLAVLLRMGKATVGATFSLDREPSFAMVSEKYGPDSDQY
                     RGVLAMYVFGTLFGAVFITLLTSLVANWRIFDPLALAMGAGVGSGSMMAASTASIVDAY
                     PAGEEAILGMAAVSNLITTILGVYVGIYIALPLADRFYRLLTGRRDTAAPGSGAPAASA
                     GAGSDEVADNRAFREQVAAVSTQVTLPLWLSLGVLTVLGIGTASIAAGALSWKVVGGYA
                     VLLALVLVGLLLAKVSRKISAIVWITTVGAYISSPWFPGAEVLNPLVKSVDFLSIATIM
                     LTLAGLSLGKDIPLLRRIGWKIIPVGLVAITASFLLSTVIAEFALGLWG"
     gene            complement(5208..6749)
                     /locus_tag="FDZ84_RS30465"
                     /old_locus_tag="FDZ84_30600"
     CDS             complement(5208..6749)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012398.5"
                     /locus_tag="FDZ84_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30600"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_168588678.1"
                     /sec_met_domain="Aldedh (E-value: 1.4e-154, bitscore:
                     513.9, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIPATSSAASARQALDAAFPQGLGAFIDGAIVTGGGERITLTS
                     AATGEDYADFNDPGREGADAILTSAVHGAAKWAATDAFERAAILRKVSGILSEHAEELA
                     VLESATTGKPLRDTRGEAAKVAEMFGYYAGWADKLMGRTIPVPGNWHTYTERVPWGVVV
                     AITPWNAPLFTAGWNSAAPLAAGNAVVVKPSEFTPASTVRLAQLAHQAGLPEGVFNVAV
                     GLGGTVGAALTSDPRVGKVSFVGSVATGRRVAVSAAQAGIPAVLELGGKSANIVFADAD
                     LDRAADGAIAAVFSGAGQSCVAGSRLLVQRSVHAEFVERVAERAARLRLGDPLDPDTEV
                     GPIITAPQFATVTSLIEAGLQDGGRRVTGAELPAALTGTALAAGHWVAPTLLDGVTPAN
                     RLETSEVFGPVVGADAFDTEAEAIDRANGTNFGLAGAVWTGDVSRAHHVARSVKAGTFW
                     INSYKTIHVAVPFGGFGDSGHGRSSGPGVLDEYTQTKAVWVPTRAAGAPFPSLSY"
     gene            complement(6746..7633)
                     /locus_tag="FDZ84_RS30470"
                     /old_locus_tag="FDZ84_30605"
     CDS             complement(6746..7633)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.5"
                     /locus_tag="FDZ84_RS30470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30605"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_168588679.1"
                     /transl_table=11
                     /translation="MDKQIAVVGLGSMGGAMASTLHRAGWQVSGFDPSPDARSAAGSGG
                     IRTVDDVGLLAGTPYVVLSLPSARVVEATVPQLLESAGTIAIVDTTTSEPATSAKLAVL
                     AAERGAAFVDAPVSGGRAGAATGRLTAFVGATPDGLDAARPVVEALTGGQYQHLGGPGS
                     GNVVKLLNNVLAAANLVSVGEALAVAKAYGVDPAIAAAGISGASGASLVSAAMYPDWVL
                     SGTHDSGFSLGLMARDAALAIEIAGQRGEQPGLLAAASQRWQDALARLGPSADFTEIAR
                     TVAPSLTREGSPKS"
     gene            complement(7669..8547)
                     /locus_tag="FDZ84_RS30475"
                     /old_locus_tag="FDZ84_30610"
     CDS             complement(7669..8547)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013539.5"
                     /locus_tag="FDZ84_RS30475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30610"
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="WP_210435217.1"
                     /transl_table=11
                     /translation="MSTAHNDEIFGNADAQWLGDVLPGVPLSKAQSRVVDVIVRNPQLA
                     SYADIAEIAQRADVNNSTVVRAAQTLGYRGWPDLQRELRARYLVLISSEDTLVEHGEHR
                     SPLHDALTHDIDNLRQALDTNTAADAEAAIAALAAARSILVVGVGSFAGPASVMAHLGS
                     TMGYPISLENRAGVHLATAINSLGPGDVLVVINMWRSMKQLIATTEAARAAGATIIAIT
                     DMRRGRLATTVADHLLIVPSEGISFFQSVTAATSVVYGLLAGMQAAQPERSRAAIRRTQ
                     QLWKDLDIYLD"
     gene            complement(8668..9879)
                     /locus_tag="FDZ84_RS30480"
                     /old_locus_tag="FDZ84_30615"
     CDS             complement(8668..9879)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692749.1"
                     /locus_tag="FDZ84_RS30480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30615"
                     /product="MFS transporter"
                     /protein_id="WP_168588681.1"
                     /transl_table=11
                     /translation="MPAAEPGRITVRELLARPVYRRWWAAAVISRAGDILAGVTLLLLV
                     LDRTGSGLGVAGVVIADVVPVLLFAPVAGVVVDRLPRRRIMIAADLVRMALAALLPLVG
                     THLGAVYAIAFALSAAAVFFNPAANSLLPALVGERELVAANSGIWTTAIVAQIALAPLA
                     GALAAVAGYAAAFWLNAASFAISAMLLTGLAVPGHRAATSQGWARDALDGVRLLVADRL
                     LRSLATAQLLAALSAGATSALLVVLVRERLGLGPQGFGWLLATIAVGALAGPALLTRIV
                     RGPVRPGIVFGAYGVRGLVDVLLALTTWPLLAAAALLFYGLSTSTGTITFTSLVQTHTG
                     EAARGRVFAGFDALFQTGRLVSLLLGGVLADWLGITAVYFLGAALLLTAAASGFGPRRS
                     AQST"
     gene            complement(10001..10282)
                     /gene="pqqD"
                     /locus_tag="FDZ84_RS30485"
                     /old_locus_tag="FDZ84_30620"
     CDS             complement(10001..10282)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874340.1"
                     /locus_tag="FDZ84_RS30485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30620"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_168588682.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.5e-21, bitscore:
                     73.5, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.7e-12, bitscore: 45.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTALQPSSQPRLASHVRLGFDRARKQYMLQVPESATVLNLTGAT
                     TLHLCDGRRTVAEIVEKLRDRYDHVADDDVANFLARLVAKRWVELGGD"
     aSDomain        complement(10013..10273)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FDZ84_RS30485_PqqD_RRE.1"
                     /evalue="1.30E-23"
                     /identifier="RREFam006.1"
                     /label="FDZ84_RS30485"
                     /locus_tag="FDZ84_RS30485"
                     /protein_end="90"
                     /protein_start="3"
                     /score="73.5"
                     /tool="antismash"
                     /translation="ALQPSSQPRLASHVRLGFDRARKQYMLQVPESATVLNLTGATTLH
                     LCDGRRTVAEIVEKLRDRYDHVADDDVANFLARLVAKRWVEL"
     gene            complement(10395..10532)
                     /gene="pqqA"
                     /locus_tag="FDZ84_RS30490"
                     /old_locus_tag="FDZ84_30625"
     CDS             complement(10395..10532)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692751.1"
                     /locus_tag="FDZ84_RS30490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30625"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_168588683.1"
                     /transl_table=11
                     /translation="MQSDTARTALEWEPPKFEEVDWEAPDFEELACASEVTMYVSRMED
                     "
     gene            complement(10678..10833)
                     /locus_tag="FDZ84_RS30495"
     CDS             complement(10678..10833)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS30495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_168588684.1"
                     /transl_table=11
                     /translation="MKISTIFSSRGGGWGGRGGGWGGRGGGWGGWGRGGWGGWGWGGWG
                     WGGWGC"
     misc_feature    10812..10826
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    complement(10886..10902)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.03"
                     /tool="antismash"
     gene            11241..11537
                     /locus_tag="FDZ84_RS30500"
                     /old_locus_tag="FDZ84_30630"
     CDS             11241..11537
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS30500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FDZ84_30630"
                     /product="hypothetical protein"
                     /protein_id="WP_168588685.1"
                     /transl_table=11
                     /translation="MRENSRVLFGILGSAGGAGLAALNGDGERAALLLGIAKTLVGRTS
                     TAHRELVSDFGAALERGAALAYDQAIALLTGESGNSPRARSRSRPSGSRARSP"
     gene            complement(11461..11679)
                     /locus_tag="FDZ84_RS30505"
                     /old_locus_tag="FDZ84_30635"
     CDS             complement(11461..11679)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS30505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FDZ84_30635"
                     /product="hypothetical protein"
                     /protein_id="WP_210435218.1"
                     /transl_table=11
                     /translation="MLGDAGYGATLGGLGSGQALVAAYVLAGELAAADGDHRTAFVRYE
                     HQIKDFARGCQKAANAIWLADYSRFLR"
     gene            11797..12606
                     /locus_tag="FDZ84_RS30510"
                     /old_locus_tag="FDZ84_30640"
     CDS             11797..12606
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692753.1"
                     /locus_tag="FDZ84_RS30510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30640"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_168588686.1"
                     /transl_table=11
                     /translation="MTASTMPICATCGTQYARPRPDCPVCEDERQYVPQGGQQWTDLAS
                     VRSDERKALIREQDDVLGIGCEPRFAIGQRALLLRTDAGNVLWDCVSYLDDEIISTIND
                     LGGLIGIAISHPHYYTTMVEWAHAFDVPVHLHANDQQWIGRPDPSIRLWEGTTNELAPG
                     LTLINLGVHFAGGTVLHWDSGEGALFTGDIVQVIPDRTHVAFMYSYPNLIPERPSVVRR
                     AAQLLEPYRFDALYGAWWDTVIPTDARGIVQRSAARYLRYALDDVEN"
     gene            complement(12612..13019)
                     /locus_tag="FDZ84_RS30515"
                     /old_locus_tag="FDZ84_30645"
     CDS             complement(12612..13019)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014058.5"
                     /locus_tag="FDZ84_RS30515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30645"
                     /product="archease"
                     /protein_id="WP_168588687.1"
                     /transl_table=11
                     /translation="MNGFRFLPHTADIRFEAWGSTREECLAAAARALVAAFAEVAVDGP
                     ESTRTVEFDGTDEQLLLAVLDEIIYLLDAEGTVPLDIRVQPLATGIALELANVAVARAE
                     IIGAAPKAVSLNELQIEHDSRGWHCAATIDV"
     gene            complement(13324..14736)
                     /locus_tag="FDZ84_RS30520"
                     /old_locus_tag="FDZ84_30650"
     CDS             complement(13324..14736)
                     /EC_number="6.5.1.8"
                     /GO_function="GO:0008452 - RNA ligase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692757.1"
                     /locus_tag="FDZ84_RS30520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30650"
                     /product="RtcB family protein"
                     /protein_id="WP_168588688.1"
                     /transl_table=11
                     /translation="MELVEETPYRFRIEQHGAMRVPGVVFASRRLLPSKGDGALDQVVN
                     VAALPGIVGASYAMPDMHWGYGFPIGGVAATDVRAGGVVSPGGVGFDISCGVRLLAAEL
                     DRPDFRRVAERIMDGLSRATPRGAGRGAVWELPREGLDRLLEEGCHYAVARGRGTPRDL
                     ERCEDGGAVADAQPGRVSARARDRGLGQVGSLGSGNHFLEVQAVAEIYDEGVAGAFGLR
                     LDQLCVMIHCGSRGLGHQICTDHVRSMDESMADYGLTVPDRQLACTPVDSPAGRAYLGA
                     MAAAANYARANRQVLGVAAGEVLRKVTGRGLDLVYDISHNLAKIETHEVEGQRRTLCVH
                     RKGATRALPPGHPELPPSLREAGQPVLIPGSMGTASYVLTGVPTGDAFFSTCHGAGRTQ
                     SRHQAIRTTDPRRLRRDLEHDGIVVRGSSARGLAEEAPTAYKDVDAVVAAAEGAGLCRR
                     IARLVPLGVVKG"
     misc_feature    complement(14305..14307)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14885..16222)
                     /gene="dctA"
                     /locus_tag="FDZ84_RS30525"
                     /old_locus_tag="FDZ84_30655"
     CDS             complement(14885..16222)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006835 - dicarboxylic acid transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dctA"
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010692759.1"
                     /locus_tag="FDZ84_RS30525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30655"
                     /product="C4-dicarboxylate transporter DctA"
                     /protein_id="WP_168588689.1"
                     /transl_table=11
                     /translation="MAQPTSPVQRGRVSRVLSSLFVQVLIAAVLGIAVGHFWPDFGGAL
                     KPIGDGFIRLIKMVIAPLIFCVVVVGIAKAGDMRSVGRIGLKALIYFEVVTTAALALGL
                     IAGNVIQPGAGLNVDPATLDASGVTAKTHGEQMPGPAQFVLHMIPESAVAAFADNELLQ
                     VLLLAVLFAAGLLHIGIGRAPQVFAFIEQTGEIIFKIIGFVMRLAPIAVFGSMAYLIGQ
                     YGLSSLSTYATLIGACYGAALLFCVVLGVLLKAFTGLHLLRFLRYTREEFALAVGTASS
                     EVVMPRIMEKLERAGCRREAVGLVIPTGYSFNLDGASIYLSLATLFMAQAVGVDLTIGQ
                     QITVVLVLVLTSKGMAGIPGSAFIALSATAGAVGVIPVAAVALMLGADRIMDTMRVVTN
                     LLGNCVATFIVSKWDGALDCDRARATLADPASAPPLPREEDEPAKA"
     misc_feature    complement(16233..16247)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.67"
                     /tool="antismash"
     gene            16625..17113
                     /locus_tag="FDZ84_RS30530"
                     /old_locus_tag="FDZ84_30660"
     CDS             16625..17113
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016060.5"
                     /locus_tag="FDZ84_RS30530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30660"
                     /product="GtrA family protein"
                     /protein_id="WP_168588690.1"
                     /transl_table=11
                     /translation="MRVLAAREPGALAPVAADPPRTAPRDNVLGQAVLFTVVGVLATAA
                     NAVLYVLLREIFPTGASNSCSLLITTAASSMAHRHFAFAGRDEHPIRMHLQTLAVFLFY
                     CVSNSIALDLLGLAVEDPSSVVEAAAVAAMSIIGGTTRFVVMRLWVFSRSRAHRSSRE"
     gene            complement(17084..18112)
                     /locus_tag="FDZ84_RS30535"
                     /old_locus_tag="FDZ84_30665"
     CDS             complement(17084..18112)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS30535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FDZ84_30665"
                     /product="hypothetical protein"
                     /protein_id="WP_168588691.1"
                     /transl_table=11
                     /translation="MTPADVLIRLATNVPATDTEADDWRARNMAELLLAARTSRDPLLV
                     SAVDDFVLTSPPVYSRFADRLRRMRGFLADAPADYVEDRKQDPEAPWPRPAVRARAAQL
                     ARFVDSCTPEGWDEEHTEPADAADVSAELDRNARTRVLGRTGHHCVDTDLPAELVWREW
                     LVDNNRPTLVVVAKQRTAATRVVRWGLHLHMASHMDHLAELTEHSGPAAATQLQFGEGL
                     LIAEAVAMACEFIALADADRTSALYRESLRRLAVNRLRRLPRIAEWGAAALPGSPTMAE
                     VVHSVAVDEFTVLPTLAEAYVAGPFDLADQGFDHPLIPPRLRTALVEKFRIALLPAGAM
                     RP"
     gene            complement(18109..18849)
                     /locus_tag="FDZ84_RS30540"
                     /old_locus_tag="FDZ84_30670"
     CDS             complement(18109..18849)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (21-147). E-value: 2.4e-11. Score:
                     35.8. Matches aSDomain:
                     nrpspksdomains_FDZ84_RS30540_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.5"
                     /locus_tag="FDZ84_RS30540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30670"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_371812708.1"
                     /sec_met_domain="TauD (E-value: 3e-09, bitscore: 35.8,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHCGPYCPAGTIAPRRKDHGKATMTSVLETLTNQGWALIDGAGF
                     TDGSDVDYRAVERIASRYGTASDRDGGQAIWPVTPRKSGSTDTFSVRAGEARFHTDAAY
                     RAEPEQRFALFCVRPAEDGGASRLLQARKALSGLPGEMSALLRKPVWRWIPPATFGGEP
                     DISRSVSREDGRIRWRVDNLDVDSALRSVATDFDEHLDSHPDAAEFVLGTDSVLICDNE
                     RVLHGRTWFSDPRRLILRVRLVIR"
     aSDomain        complement(18409..18786)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FDZ84_RS30540_TauD.1"
                     /evalue="2.40E-11"
                     /label="FDZ84_RS30540_TauD.1"
                     /locus_tag="FDZ84_RS30540"
                     /protein_end="147"
                     /protein_start="21"
                     /score="35.8"
                     /tool="antismash"
                     /translation="KATMTSVLETLTNQGWALIDGAGFTDGSDVDYRAVERIASRYGTA
                     SDRDGGQAIWPVTPRKSGSTDTFSVRAGEARFHTDAAYRAEPEQRFALFCVRPAEDGGA
                     SRLLQARKALSGLPGEMSALLR"
     misc_feature    19010..19024
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.23"
                     /tool="antismash"
     gene            19041..20195
                     /locus_tag="FDZ84_RS30545"
                     /old_locus_tag="FDZ84_30675"
     CDS             19041..20195
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098711.1"
                     /locus_tag="FDZ84_RS30545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_30675"
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="WP_168588693.1"
                     /transl_table=11
                     /translation="MTGFAEYQREIVQLGEDGVSLPFTTDLAALEDAVRAKVPAGPYWY
                     VAGGAGTGATVRANRAAFERWRIVPRMLRNADRRDLSTTVLGMHLPAPVLLAPVGVQSI
                     LHPESELASTRAAAELGLPSVLSSSSSRTLEEVASAGCDAPRWMQLYWSSDREICASIL
                     DRGKRAGFSALVVTVDTWARGWRPHEMDRRYYPAEQGIGMAIPFSDPVFRSRLAKPPEE
                     DLAAALQLWQRMPTDAGKSWQQFSFLRDHWSGPIVVKGILHPDDARHAVARGADGIVVS
                     NHGGRQVDGAVGALEMLPEVVDAVGAEVDVLFDSGIRTGADVIKALALGAKAVLVGRPY
                     AYGLAQAGEAGVRHVLRSLLADIDITLGLVGYRSPAELDRDALR"
ORIGIN
        1 tgcacgcgat cgtcgctgcg ggcgttccgg cgcggggatg ggcggtcgcg tccgggctgc
       61 tcagcgtgct cgccggtatc gccttgctgg cctaccccgg cctcgggctg gtgaccctga
      121 cctacatcct cggcatctgg ctggtggtgt acggggttgt cgccgctgtc cgagcagttc
      181 gagtgcggcc gcatgcagca gcggcacccg cagcgcatgc gggcccagca ccggcgtagc
      241 cggagttcgc catgagcagt cagcggagcc agcgttcacc ggacaggacg catcgttggg
      301 cgtccccccg cgccattacg agcttggtgc ttgtcgtggc ggcagtggtg ctcgtgctcg
      361 agaaccggca aaccgtcgag atcaggatct tcgtgccgtt ggtcacgatg ccgatgtgga
      421 cggcgctggc cgtgatgctg gtcgtcggga tcgtcgtcgg gctcttggtg tcccgtcccc
      481 ggaaatgagg gggagctggc gggcccggcg tcgcggtgct tcgatcactg cgcctcggga
      541 tggcgtcgtg gtctgaggtc gcccgaggtg tgcaggtcca cgctttcaat cgcggtccag
      601 taccgggtgg cgtccgtgac ggccacggcc aactcggcgc tgagcgtggc caggtgggtt
      661 ccggcgagcc tcagcttgtc tccggggtga ttgctggtct tggcccgctc cacatcctgt
      721 tcgtcgaagc gcccaacctg ttcggccagc acggagctca gttggctgag ctcggcgagc
      781 gtgcccacga tcgccgagcc gaaggcgtgg agttcgttca aggacggctg cggggtcctg
      841 gcctgcaggc tcacggactc tgccacagca tcccgcccgc ggtgcagcgc ttccagggga
      901 tgttcgtgct cgggcatggg agatgcctcc tcggctgagt ggcgactcca gcggctgcgg
      961 agcggggaag ccctgttcgg aggcttcgct gcccggtggc gcaagaaggc gcggtaacgc
     1021 tgaagtaccc gatttcgctg accgactccc gtgctcagga ctccggcggt cggtggacgt
     1081 tgtctcagtc gtcgacggac aaccgggcga ggcgccgggc cgttggccaa cgcacgtggg
     1141 tgacccaacc gagcttctcg aagatccgga tcagccgcgc ggagatgtcg atctggccag
     1201 gccggacgcc atgccgagcg caggtcgggt cggcgtggtg caggttgtgc cacgactcgc
     1261 ccatgctcag cagggcgagc ggccagaagt tggccgcctt gtcgcggctg cggaacgggc
     1321 gctccccgaa catgtggcag atcgagttca ccgaccaggt cacgtggtgc aggaaggcga
     1381 cgcggaccaa cccggcccag aagaaggacg tcgcggcacc ccaccaggtg ccggtgatca
     1441 agccgccgca caacgcaggc agcgcgaacg tggccacggt cagcggcccg aacaaccggt
     1501 gcactagccg gatgtcgggg tcggccagca gatcgggcgc gaaccgctgc tgattcgtca
     1561 gatcccggtc gaagatccag cccatgtgcg cgtgccagaa cccccgcgcc aacgcgacgg
     1621 gggacgtgcc gaacgcccac ggcgagtgtg gatcgccctc ccggtcggcg aacgcgtggt
     1681 gcctgcgatg atctgcgacc cagtgcagga tcggtccctg gaccgccatg ctgcccgcga
     1741 ccgcgagtgc gatgcgcatc cagcgcttgg cgcggaacgc gccgtgcgtg aagtagcggt
     1801 ggtagccgac cgtcacgccg aggatggtga acacgtacca gccgacggcg agcagcgcat
     1861 cccaccagcg caagccccac ccccacacca gcggcacagc cgcgatcaag gccaggaacg
     1921 gcacgaggat gaacgcgtag accgacaggt gcggggccag tggcctgcgc ccggccagca
     1981 gcggttgggg attcgacttg gacacgtcgc tggcgaccat cgcagcagaa acctcgaatc
     2041 cgcctagtcg gaagctctgc caccaccgac cgggaggcag ccgttcaccc accacacaac
     2101 cggcaagggg cacgaagagc aacgaaccgc ccggcaagca ttggtgaacg cgggtgaagg
     2161 gcttggtgtc gagacactgc tgccggatcc cctcatgaac gtgcggtcag gtctgtgctg
     2221 gaggaaaagc ccggtcgctt tcgacctcga cccggttgcg gccggcgtgc ttcgcccggt
     2281 agagggctcg gtcggcggcg gcgaataggg ggacgaaatg ggtggggccg atggcgacgc
     2341 cgacgctgac ggtcggcggt cgggttctcg agcccacctg cggcgtccag tcgtgggtct
     2401 ccacagcggc gcggatgcgc tcggccagct ccgggccgcc ggggcctgga gcctgttccc
     2461 ggtcggcgag cagtaccagg aactcgtcgc ccgcccatcg gcagacgagg tcgtcggagc
     2521 ggcactcgcg ccgcagcagc cgggccacct cctgcaagac ggcgtcgcct gcggtgtggc
     2581 ccgcggcgtc gttgatcttc ttgaagttgt cgacgtccat cacgaccagc caccgcaccg
     2641 cggcttgatc ggcagccgag gcccggtgct ccacgccgcg ccggttgagc aggccggtca
     2701 gcgggtcccg gcacgcgtcc tgctgcgcgg cggactcctg gcgctgcgcc tggatggcga
     2761 cgcggcgttg ctccagggcc tgaccgagcc cgacctgcag cacgcgcatc gccgttctgc
     2821 tggcggccac caggctgcgc agcgcggcgg cctcgccgac ggggtcgtcc agctctcggc
     2881 agatcgtggt cagggccagc gagaaccgcg tccgcagcct ggtgtcccgg atccattccg
     2941 ctgtttcgac ggctcggctg gcgaaagtcc gggcttcggc caggcggtgc tggtgccgac
     3001 ggatctcggc gagcacccag ttcgcgatcg ccgaggtgta gcggtcctcc gcttcctcgc
     3061 tcgccgtcag ggcctgcacc gcgcggctct ccgcttcggc gacgtgcccg agggcggcca
     3121 gcgcccgggc gctgccggcc tgaacgcggt tgcggatctg tcctggggag gccagcgaca
     3181 gcgcttcgtc gaagagctcc agcgccgtgc ggaagcactc gtccgcggcg ccgttggcct
     3241 ccatggcccg cagttgccag cagttggcct cccgctccag gcagtgcgcg aggatctccg
     3301 gcgcaccgca gcgccgggcg acctgaaccg actgggtgat gagctcgcgc gcggcgtcgt
     3361 ggtgcccgac tgcctgcagc agatccccga gcatgcccat cgcctgggcg gcggagccac
     3421 cctgcggccg gtcgacgtcg agcacggtcc acccctcggc gacgaggtcg agggcgagcg
     3481 gaatccgatc gagccgccac gccaggtagg cccggtgcac gagcacgacg ctggagtccc
     3541 accggccatc gacgtggttg gccccgtcgg cgaccagccg cctgaaggcg aggccggcgg
     3601 cgttcgggcg gccggactcc agcaacatcc ggacgtgccg gtccggctcg gggaccagcc
     3661 ccgccatcaa cggatcgttc tcccgcactg cctcatcctc gcagccacgc aacccggtga
     3721 cctgctgttc tgagccaccg cgctgcgttc agagtaccga tcccagcgga ttgctcagcc
     3781 ccaaaggccg agggcgaact cggcgatcac ggtcgacagg aggaacgacg ccgtgatcgc
     3841 gaccaggccg accgggatga tcttccagcc gatccgccgc agcagcggga tgtccttgcc
     3901 cagcgacagc cccgccaggg tcagcatgat ggtggcgatc gagaggaagt ccaccgactt
     3961 caccagcggg ttcagcacct ctgcgccggg gaaccagggg ctcgagatgt aggcgcccac
     4021 cgtggtgatc caaacgatcg ccgagatctt ccgggacacc ttcgctagga ggagcccgac
     4081 caggaccagg gccaggagca ccgcgtaacc gccgacgacc ttccagctca aggcaccggc
     4141 cgcgatcgag gcggtgccga tgcccagcac cgtcagcacc ccaagcgaca gccacagcgg
     4201 cagcgtgacc tgggtggaga ccgcggcgac ctgctcccgg aacgcgcggt tgtccgcgac
     4261 ctcgtccgac ccggcaccgg cggaagccgc tggcgcgccc gatcccggag cggcggtgtc
     4321 ccggcgtccc gtgagcagcc ggtagaaccg gtcggccagc ggcagcgcga tgtagatccc
     4381 gacgtacacg cccaggatcg tggtgatcag gttcgacacg gcggccatgc ccaggatggc
     4441 ctcttcaccg gccggatacg cgtccacgat gctcgccgtg gacgccgcca tcatcgagcc
     4501 ggacccgact cccgcgccca tggccagcgc cagcggatcg aagatccgcc agttggccac
     4561 gagggacgtc aggagcgtga tgaacaccgc gccgaagagc gtgccgaata cgtacatcgc
     4621 cagcacgccg cggtactggt ccgagtccgg cccgtacttc tccgagacca tcgcgaacga
     4681 cggctcgcgg tcgagggaga acgtggcgcc gaccgtggcc ttgcccatgc gcagcagcac
     4741 ggccagcggc agggcgaggg cgatcgtccc gagcaggtgg ccgacctcct gcagcagcag
     4801 ggcgggcccc gctttgacca gggtcggcag gctcgggccg atgttgaagg cgagccgggc
     4861 caccagcagc atcaccgcca cgccgaccaa ggccgaggcc gccttctgca ggtccaagcc
     4921 gagcggcttg aaccgctgca ccgacaccag caggccgagg accagccccc acaccatcgg
     4981 gaagatgatg atggacccga tgcccagatc gatcttgact tggccgacga actggacgac
     5041 cagcgcgatg accagcgcca gggcggcgat cggcagcgtt tgcttcgttc cggcctcggc
     5101 cggggcggtg gaaatggtca tcgggctgct gcttcctgcg aggggttccg gcggtgggcc
     5161 gccgcggtga accggtcttt ctgctgattc ggtcccatga cgccgcccta gtagctcagc
     5221 gatgggaacg gtgcgcctgc ggcgcgggtg ggcacccaga cggccttggt ctgggtgtac
     5281 tcatcgagca cacccgggcc ggaggagcgg ccgtggccgg agtcgccgaa gccgccgaag
     5341 gggacggcga cgtggatcgt cttgtaggag ttgatccaga aagtgccggc cttgaccgag
     5401 cgtgccacgt ggtgggcgcg ggacacgtcg ccggtccaca ccgcgcccgc caggccgaag
     5461 ttcgtgccgt tggcccggtc gatcgcttcc gcctcggtgt cgaatgcgtc ggcgccgaca
     5521 acgggaccga acacctcgct ggtctccaac cggttggcgg gtgtgacccc gtcgagcagg
     5581 gtaggcgcga cccagtgacc ggccgccagc gcggtgccgg tcagcgcggc gggcagctcc
     5641 gcgccggtga cccggcggcc gccgtcctgc agccccgcct cgatcaggga ggtcacggtg
     5701 gcgaactgcg gtgcggtgat gatcgggccg acctcggtgt cggggtcgag cggatcgccg
     5761 aggcgcaatc gcgccgcccg ctccgcaacg cgttcgacga actcggcgtg gacgctgcgc
     5821 tgcaccagca gccgcgaacc ggccacgcag gactgcccgg cgccggagaa cacggccgcg
     5881 atggcaccgt cggccgcgcg gtccaggtcc gcgtcggcga agacgatatt ggcgctcttg
     5941 ccgccgagtt cgaggacggc cgggataccg gcctgggccg ccgataccgc cacccggcgg
     6001 ccggtggcca ccgagccgac gaacgagacc ttcccgacgc gcgggtcgct ggtgagcgcg
     6061 gcgccgacgg tgcccccgag gccgacggcg acgttgaaga cgccttccgg cagaccggcc
     6121 tggtgcgcca gctgggccag cctgacggtg gaagccgggg tgaactcgct gggtttgacg
     6181 acgacggcgt tgccggcggc cagcggggcg gccgagttcc aaccggccgt gaacagcggc
     6241 gcgttccacg gcgtgatggc cacgacgacg ccccagggga cgcgttcggt gtaggtgtgc
     6301 cagttgccgg ggacggggat ggtccggccc atcagcttgt cggcccaccc cgcgtagtag
     6361 ccgaacattt cggcgacctt ggccgcctcg ccccgggtgt cccggagcgg ctttccggtg
     6421 gtggcggact ccagcacggc cagttcctcg gcgtgctcgg agagtatgcc ggagaccttg
     6481 cgcaggatcg ccgcccgttc gaaggcgtcc gtcgcggccc acttcgcggc cccgtggacc
     6541 gcgctggtca ggatggcgtc ggcgccttcc cggccgggat cgttgaagtc ggcgtagtcc
     6601 tcgccggtgg cggcggaggt gagggtgatg cgctcgcccc cgccggtgac gatggcgccg
     6661 tcgatgaagg ctccaaggcc ttgcgggaag gcggcgtcca aggcctggcg tgcagatgcg
     6721 gccgaagaag tggccgggat ggtgctcatg atttggggga tccttcgcgg gtgagggagg
     6781 gggcgacggt tcgcgcgatc tcggtgaagt cggcgctggg gccgaggcgg gcgagggcgt
     6841 cctgccagcg ctggctcgcg gcggccagca ggccgggctg ctcgccgcgc tggccggcga
     6901 tctcgatggc cagggcggcg tcccgggcca tcagcccgag ggagaaaccg gagtcgtggg
     6961 tgccggagag cacccagtcc gggtacatcg cggcggagac caagctggcg ccggaagctc
     7021 cgctgatccc cgccgcggcg atggcgggat ccacgccgta ggccttcgcg acggctaggg
     7081 cctcaccgac ggacaccaga ttggccgcgg ccaggacgtt gttgagcagc ttgaccacgt
     7141 tgccggagcc ggggccgccc aggtgctggt actggccgcc ggtcagggcc tccaccacgg
     7201 gccgggccgc gtcgaggcca tctggcgtgg ccccgacgaa cgcggtcaac cgccccgtcg
     7261 cggccccggc tcgcccgccc gagacgggtg cgtccacgaa ggccgcgccc cgttcggcgg
     7321 cgaggacggc gagcttggcg ctggtggccg gctccgacgt cgtcgtgtcg acgatcgcga
     7381 tggtgcccgc gctctccagc agttggggga ccgtcgcctc gaccacgcgg gccgagggca
     7441 gcgagaggac tacgtagggc gttccggcca gcaagccgac gtcgtccacg gtgcggatgc
     7501 cgccacttcc tgcggcggaa cgcgcatcgg gggaggggtc gaacccggac acctgccagc
     7561 cggcccggtg cagggtggag gccatggcac cgcccatcga ccccaggccg acgacggcga
     7621 tttgcttgtc catcagagct cctgttcgtg gggacgttct ggttcgtcct agtcgaggta
     7681 gatgtccagg tccttccaca gctgctgggt gcggcggatg gcggcgcggc tgcgttccgg
     7741 ctgcgccgct tgcatcccgg cgagcagccc gtagacgacc gaggtggccg cggtgacgga
     7801 ctggaagaag gaaatgcctt ccgacggcac gatcagcagg tggtcggcca cggtggtggc
     7861 cagtcggcct cggcgcatgt cggtgatcgc gatgatcgtc gcgcctgcgg cgcgggctgc
     7921 ctcggtggtg gcgatgagct gcttcatgga tcgccacatg ttgatgacca ccaggacgtc
     7981 gcccggtccc aggctgttga tggcggtggc caggtgcacc ccggcccggt tctccaggga
     8041 gatcgggtag cccatggtgg aaccgaggtg ggccatgacg ctggccgggc cggcgaagga
     8101 gccgacgccg accacgagga tcgacctggc cgccgccagt gccgcgatgg cggcctccgc
     8161 gtcggcggcg gtgttggtgt ccagcgcctg gcgcaggttg tcgatgtcgt gcgtcagggc
     8221 gtcgtgcagc gggctccggt gctcgccgtg ctcgacgagc gtgtcctcgg aggagatcag
     8281 caccaggtag cgggcgcgca gctcgcgctg caggtccggc cagccccggt agcccagcgt
     8341 ctgggcggcg cggaccacgg tggagttgtt gacgtcggcc cgctgcgcga tctcggcgat
     8401 gtccgcgtag gacgcaagtt gcggattgcg gacgatcacg tcgaccacgc gcgactgcgc
     8461 cttggagagc ggcacgccgg gcaagacgtc acccagccac tgggcgtcgg cgttgccgaa
     8521 gatctcgtcg ttgtgtgctg tggacacgaa ccctgctccc ggatacgagg cggagcgccc
     8581 tgcaagcgcg attgcgacaa tgtacatcgc aattttgatt gcagaaagac cctgttgcgc
     8641 gccggatggc gaagcgccgg cgtgggatca agtcgactgc gcggaccgtc tggggccgaa
     8701 cccgctcgca gctgccgtga gcagcagcgc ggccccgagg aagtagacgg cggtgatgcc
     8761 gagccagtcg gcgagcacgc cgcccagaag gaggctgacc aacctgccgg tctggaacag
     8821 cgcgtcgaat ccggcgaaga cgcgacctcg cgctgcctcg ccggtgtggg tttgcaccag
     8881 gctggtgaag gttatggtgc cggtcgaggt gctcaggccg tagaacagca gcgccgcagc
     8941 cgccaacagg ggccacgtcg tcagggccag cagcacgtcg accaagccgc gaacgccgta
     9001 tgcaccgaag acgatgcccg gccggaccgg gccgcgcacg atccgggtca gcagggcggg
     9061 gccggcgagg gcgccgacgg cgatggtggc caagagccag ccgaaaccct gcgggcccag
     9121 accgagccgt tcccggacga ggacgacgag caaagcgctg gtggctccgg ccgacaacgc
     9181 ggcaagcaac tgcgccgtgg ccagtgagcg cagcagccgg tcggccacga gcagccggac
     9241 gccgtcgagg gcgtcgcgcg cccaaccctg cgaggtcgcg gcgcgatgac cgggaaccgc
     9301 caagccggtg agcagcatgg cgctgatggc gaacgatgcg gcgttgagcc agaacgcggc
     9361 ggcgtaaccg gccacggcgg cgagcgcgcc ggccagcggt gcgagcgcga tttgggcgac
     9421 gatcgcggtg gtccagatgc cggagttggc ggcgacgagt tcgcgttcgc cgaccagtgc
     9481 cggtagcagg ctgttggctg cggggttgaa gaacaccgcg gcagccgaga gcgcgaacgc
     9541 gatcgcatag accgctccca ggtgggtacc gaccagaggc agcaacgcgg cgagggccat
     9601 gcggacgagg tcggctgcga tcatgatgcg gcgtcgaggc aggcgatcga ccacgacgcc
     9661 ggccacggga gcgaacagca gcaccggcac gacgtcggcg atcaccactc cggccacacc
     9721 cagacccgag cccgtgcggt ccaggaccag caggagcagc gtcaccccgg ccaggatgtc
     9781 cccggcgcgc gagatcaccg cagcggccca ccacctccgg tagacgggcc gcgcgagcaa
     9841 ctcccgcacc gtgatccggc ccggttctgc cgctggcaca gatgtcctcc cgcagcttcc
     9901 cgacggtgtg agggcaggac ctgttattca ggaggccggg ttgagcgggt tggggcagca
     9961 cgggcagcgt gcacgcgcct gggcccgcag cccggaccgg tcagtcaccg ccgagttcca
    10021 cccaccgctt ggcgacgagg cgggcgagga agttcgccac gtcgtcgtcg gccacgtggt
    10081 cgtagcggtc gcgcagcttc tccacgatct cggcgaccgt gcgccgtccg tcgcacaggt
    10141 gcagggtggt cgcgccggtc aggttcagca ccgtcgcaga ttcgggcacc tgcaacatgt
    10201 actgcttccg tgcccggtcg aagcccaagc gcacgtgcga ggccaatctg ggctggctcg
    10261 atggctgtag tgctgtgctc atcgccgtct cagttcactc ggtccggaaa gctcggtctg
    10321 cgggcctgcg tcggcgagca ggtttctcgc ggtggtctgc tcgtcgacgc aggggccact
    10381 gctggtgttc ggtgctagtc ctccatccgc gagacgtaca tcgtcacttc ggacgcgcac
    10441 gcgagttctt cgaagtccgg ggcctcccag tcgacttcct cgaacttcgg gggctcccat
    10501 tcaagagccg tccgagcggt atcggattgc atggtcggca cctccgctct gcggatttca
    10561 ccgtcttgca ggggagctcc cgcctgcggg caggcgggag ctctgcggtt gacaagagcc
    10621 ggtttacggg ctgaaagccc gggctagtcg gatgagattg gtggggtcag ggcgcgatca
    10681 gcagccccag ccgccccaac cccagccgcc ccagccccag ccgccccagc cgccgcggcc
    10741 ccagccgccc cagccgccgc cacggccgcc ccagcctccg ccgcggccgc cccagccgcc
    10801 gccgcgggag ctgaaaatcg tgctgatctt catcgtgatc cctcatcttt tcaaaagggt
    10861 tcaacgactt tcgttggacc ttcggatgtt gctttgcaac caacaacgcc gacgtcgttc
    10921 cggaaagcgt cagcccggga tggtcgggaa tgtgaacgat cgctctgcgt ggtgttgcac
    10981 ttgcaaccat agagttaaag ggtggtgtca acaggggact ttcgtcctca gcactatctg
    11041 tagccccttt ggttgcgcta cgtattcggg tgtcgcgctg cggccaacgc gccggtcgcg
    11101 aaatcgcgtg cccggagcat ccactgtgga attatctttc gcgggatctg cgcgcgattt
    11161 ccagctgtca gagacggttg tgcgggcggc tggaccgcct acgtggtcca tggccgcatg
    11221 tgtggctgcc gtggttcggc gtgcgcgaga attccagggt gctgttcggg attctgggtt
    11281 cggctggagg tgctgggctc gccgcgctca acggcgacgg cgagcgcgcc gcgctgctgc
    11341 tggggatcgc gaagaccctc gtcggccgga cgtcgaccgc ccaccgcgag ctggtgagcg
    11401 acttcggcgc ggctctcgag cgcggcgcgg cactcgccta cgaccaggcg atcgcactgc
    11461 tcaccggaga aagcgggaat agtccgcgag ccagatcgcg ttcgcggcct tctggcagcc
    11521 gcgcgcgaag tccttgatct ggtgctcgta gcggacgaac gcggtccggt ggtcgccgtc
    11581 ggccgcggcc agctctccgg ccagcacgta ggcggcgacc agcgcctgac cgctgcccag
    11641 cccgccgagg gtggcgccgt aaccggcgtc gccgagcaaa cggcgctgat cgctcgctga
    11701 cgggccgctg acgggtggtt ttcccgagtc gagcggcggg acggcgcgta aggtggacgc
    11761 cgcgctgcac gggggacgaa gggaccgcag acgaccatga ccgcctcgac gatgccgatc
    11821 tgcgccacct gcggcacgca gtacgcccga ccacgcccgg actgcccggt ttgcgaagac
    11881 gagcgccagt acgtgccgca gggcggtcag cagtggacgg atctcgcgag cgtgcgctcc
    11941 gacgagcgca aggcgctgat ccgcgaacag gacgatgtgc tcgggatcgg ctgcgagccg
    12001 cggttcgcca tcggccagcg cgcgctgctg ctgcgcaccg acgcgggcaa cgtgctgtgg
    12061 gactgcgtgt cctatttgga cgatgaaatc atcagcacga tcaatgatct cggcggattg
    12121 atcggcatcg cgatcagcca cccgcactac tacaccacga tggtcgagtg ggcccacgcc
    12181 ttcgacgtgc cggtgcacct gcacgccaac gaccagcagt ggataggccg cccggacccg
    12241 tcgatccggc tgtgggaggg cacaaccaac gagctcgcgc ccgggctaac cctgatcaac
    12301 ctcggcgtgc acttcgccgg cggcacggtg ctgcactggg acagcggcga gggagcgctg
    12361 ttcaccggcg acatcgtgca ggtcatcccg gaccgcacgc acgtggcctt catgtacagc
    12421 tacccgaacc tgatcccgga acgtcccagc gtcgtccgcc gcgccgcgca gctgctggag
    12481 ccctaccggt tcgacgcgct ctacggggcc tggtgggaca cggtgattcc taccgacgcg
    12541 cgcggcatcg tgcagcgctc cgccgcccgc tatctccgct acgccctgga tgacgtggag
    12601 aactgagcgg ctcacacgtc gatggtcgcg gcgcagtgcc agccgcgaga gtcgtgctcg
    12661 atctgaagtt cgttcagcga aacggctttg ggcgcggcac cgatgatctc ggcgcgtgcc
    12721 accgcgacgt tggccagttc cagcgcgatg ccggttgcga gcggctggac gcggatgtcc
    12781 agcgggaccg tgccttccgc gtccagcagg tagatgatct cgtcgagcac cgcgagcagg
    12841 agttgctcgt cggtgccgtc gaattcgacg gttctggtgc tttccggccc atccaccgcg
    12901 acctcggcga aagcggccac caacgcgcgg gccgcggctg ccaggcattc ctcgcgcgtc
    12961 gaaccccacg cttcgaaccg gatgtcggcg gtgtgcggca ggaagcggaa cccgttcatc
    13021 tcgactccat acggcggatg ccccggccgt caggccaggg aggagacgat cccgcgtgtc
    13081 cggctgcgca acggccactg taagatcggt tccggcaagc gaaccttgcc gccccagcac
    13141 accaagctgg aaccacaagc aacaccatgg gtaccggtgg tctatcggga gcccgcccac
    13201 ggagtgggcg aatgcctgcg gagctggcgt aagacatatc aggccgagcc tggcgcggct
    13261 ggctgtgaaa caggaaaccc agtccgcgag gactgaatct ccctgcacca accgggagag
    13321 aagtcaaccc ttcaccacgc ccagcggcac gagcctggcg atgcggcggc acagcccggc
    13381 tccttcggcg gcggcgacga cggcgtcgac gtccttgtag gcggtcggcg cctcctcggc
    13441 gagcccgcga gcggaactgc cgcggacgac gatgccgtcg tgctccaggt cccggcgcag
    13501 gcggcgggga tcggtcgtgc ggatcgcctg gtgccggctc tgcgtgcgtc cggcgccgtg
    13561 gcacgtcgag aagaacgcat caccggtcgg cacgccggtg agcacatagg acgccgtgcc
    13621 catcgaaccg gggatcagga ccggctgccc ggcttcccgc aggctcggcg gcagttccgg
    13681 gtgcccgggc ggcagcgcgc gcgtggctcc cttgcggtgc acgcacagcg ttcgccgctg
    13741 gccctccacc tcgtgcgtct cgatcttggc gagattgtgc gagatgtcgt agacgaggtc
    13801 gagcccgcgg ccggtcacct tccgcagcac ctcgccggcg gcgacgccga gcacctggcg
    13861 gttcgcgcgg gcgtagttcg ccgctgcggc catcgcgccg agataagcgc gacccgccgg
    13921 cgaatcgacc ggcgtgcacg ccaactggcg atccgggacg gtcaggccgt aatcggccat
    13981 gctctcgtcc atgctgcgca cgtggtcggt gcagatctgg tggccgagcc cgcgggaacc
    14041 gcagtggatc atcacgcaca gctggtcgag gcggagcccg aaggccccgg cgacgccctc
    14101 gtcgtagatc tcggcgaccg cctggacctc caggaagtgg ttgccggacc cgaggctgcc
    14161 gacctgcccg aggccccggt cccgcgcgcg ggcgctgacc cgacccggct gcgcgtcggc
    14221 caccgcgccg ccgtcctcgc agcgctccag gtcgcgcggc gtgccgcgcc cgcgcgcgac
    14281 ggcgtagtgg cacccctctt ccagtaaccg gtcgaggccc tcgcggggca actcccacac
    14341 cgcgccccgg cctgccccgc gcggcgtggc ccggctgagc ccgtccatga tccgctcggc
    14401 gactcggcgg aagtccggcc ggtccagctc ggcggccagc agccgcaccc cgcaggagat
    14461 gtcgaaaccg acgccacccg gtgagacgac accgccggcg cggacgtcgg tcgccgcgac
    14521 gccgccgatc gggaatccgt agccccagtg catgtccggc atggcgtacg acgcgccgac
    14581 gatgccgggc agggcggcta cgttgacgac ctggtcgagc gcgccgtcgc cctttgacgg
    14641 cagcagtcgc cgcgacgcga acaccacccc cggcacacgc atcgcgccgt gctgttcgat
    14701 ccggaaccgg tacggcgttt cctcgacgag ctccacccgg gcctcccgcg ttcctccgcc
    14761 cccggcagta cccaccgggg cccggcccga cacgcgcccg atggcagcag cgaactcggc
    14821 cccgtcggtc aggccccgtc ggtcaggccc cgtcggtcag gccttggcgg tcaggccccg
    14881 tcggtcaggc cttggcgggc tcgtcctcct cgcgggggag cggcggcgcg gacgccgggt
    14941 cggcgagggt ggctcgggcc cggtcgcagt ccagcgctcc gtcccatttg gacacgatga
    15001 acgtcgccac gcagttgccc agcaggttgg tgacgacccg catggtgtcc atgatccggt
    15061 ccgcgccgag catcagcgcg accgcggcga ccgggatgac gccgaccgcg ccggccgtcg
    15121 ccgagagggc gatgaacgcc gagccgggga tcccggccat gccctttgag gtgaggacca
    15181 gcaccagcac cacggtgatc tgctgcccga tggtgaggtc cacgccgacg gcctgggcca
    15241 tgaacagcgt cgccagcgac aggtagatgg acgcgccgtc gaggttgaac gagtagccgg
    15301 tcgggatgac cagcccgacc gcctccctgc ggcagcccgc gcgttcgagc ttctccatga
    15361 tccgcggcat cacgacctcg ctggacgcgg tgcccacggc cagggcgaac tcttcccgcg
    15421 tgtagcgcag gaaccgcagg aggtgcagcc cggtgaacgc cttgagcagc acgccgagca
    15481 cgacgcagaa cagcagcgcc gctccgtagc aggcgccgat gagggtggcg taggtgctca
    15541 gcgaggacag cccgtactgg ccgatgaggt acgccatcga accgaacacc gcgatcgggg
    15601 ccagccgcat cacgaagccg atgatcttga agatgatctc gccggtctgc tcgatgaagg
    15661 cgaagacctg tggcgcgcgc ccgatgccga tatgcagcag cccggccgcg aacagcaccg
    15721 ccagcagcag cacctgcagc agttcgttgt cggcgaaggc cgccaccgcg ctttccggga
    15781 tcatgtgcag cacgaactga gccgggccgg gcatctgctc gccgtgggtc ttggcggtca
    15841 cgccggaggc gtccagcgtc gccggatcga cattgagccc tgcgccgggc tggatgacgt
    15901 tcccggcgat gaggccgagc gcgagggcgg cggttgtgac gacctcgaag tagatcagcg
    15961 ccttgagccc gatccgcccg accgaccgca tgtcgccggc cttggcgatg ccgaccacga
    16021 ccacgcagaa gatcagcggc gcgatcacca tcttgatcag ccggatgaac ccgtcgccga
    16081 tcggcttgag ggcaccgccg aagtcgggcc agaagtgccc gacggcgatg ccgaggacgg
    16141 ccgcgatgag gacctggacg aacagcgagg acagcaccct tgacacgcgg ccgcgctgga
    16201 ccggcgacgt cggctgagcc atgtcggtct ccgattttct taatgtggaa gtatactttt
    16261 gaagttgtct cctggggctg gtccgggagt ttgcgtgctg tcgggatccg cgtcaaggga
    16321 ccgaatgtga gcgcgattca gaatttccgg cgaggcggcc ttgaactgcg gtttcggcgt
    16381 tgtcgccaag cctgactgga gtgaatccgg attgggtaca gcacggttcg aggtagctga
    16441 acccactggt atcgagggtg cgctcgggag ccggcgtcag tcgcagcgtc gcgcaccggt
    16501 ggaccgggag gatgacggct ggcaccggcg ttttccagcg tcttcccagg tagttcacgc
    16561 ggccttcccg cacggccgga ctagcttgac cgcagatctg aaccgttgcg ttggagtggg
    16621 gtccatgaga gtgctggctg cacgggagcc gggggcgctc gccccggtcg cagccgatcc
    16681 gccccgcacg gccccgcgcg acaacgtcct tggccaggcc gtgctgttca cggtcgtggg
    16741 cgtgctcgcg accgcggcga acgccgtgct ctacgtgctg ctgcgggaga tcttcccgac
    16801 gggtgcctcg aactcgtgct cgctgctgat cacgaccgcg gccagcagca tggcgcaccg
    16861 gcacttcgcg ttcgccggcc gggacgagca cccgatccgc atgcacctgc agaccctcgc
    16921 ggtgttcctc ttctactgcg tctcgaacag catcgcgctg gacttgctcg gcctggccgt
    16981 cgaagacccc tccagcgtcg tggaggccgc cgcggtcgcg gcgatgagca tcatcggcgg
    17041 caccacgcgc ttcgtggtga tgcggctctg ggtgttcagc cgctcaaggg cgcatcgctc
    17101 cagcagggag tagtgcgatc cggaacttct ccacgagcgc tgtgcgcaac ctcggcggga
    17161 taagcgggtg gtcgaagccc tggtcggcga ggtcgaacgg gccggcgacg taggcctcgg
    17221 cgagcgtggg tagcaccgtg aattcgtcga cggcgacgga gtgcacgacc tccgccatag
    17281 tgggggagcc cggcagggca gccgcacccc actccgcgat ccgcggcagt ctccgcagcc
    17341 ggttgaccgc gagtcgccgg agggattccc ggtacagggc gctcgtgcgg tcggcgtcgg
    17401 ccagagcgat gaactcgcaa gccatggcga cggcctccgc gatgagcagg ccttctccga
    17461 attgcagttg ggtcgctgcg gccggaccac tgtgctcggt gagttcagcc aggtggtcca
    17521 tgtgcgaggc catgtgcagg tgcaggcccc agcgcacgac gcgagttgcg gcggtgcgtt
    17581 gcttcgcgac gacgaccagg gttggtcgat tgttgtccac cagccattcc cgccatacga
    17641 gttctgctgg cagatcggtg tcgacgcagt ggtggccggt gcgtcccagc actcgtgtgc
    17701 gggcgttgcg gtccagctcg gcggagacgt ccgctgcgtc ggccggctcg gtgtgctcct
    17761 cgtcccatcc ttctggcgtg cagctgtcga cgaagcgtgc cagctgcgcc gcgcgggcgc
    17821 ggacggcggg gcggggccac ggggcttcgg gatcttgctt gcggtcctcc acgtagtcgg
    17881 caggcgcatc tgcaaggaag ccgcgcatcc gacggagccg gtcggcgaac cgtgagtaca
    17941 cggggggtga cgtcaggaca aaatcgtcca ctgcggacac caggagtggg tctctcgatg
    18001 tccgggccgc cagcagcagc tctgccatgt tgcgggcgcg ccagtcatcc gcctcggtgt
    18061 ccgtggcggg aacgttcgtg gcgagccgga tgagcacgtc ggcgggtgtc atctaatgac
    18121 cagcctgacg cgcaagatga gccgtcgggg gtcggagaac cacgtccgcc cgtgcaggac
    18181 gcgttcgttg tcgcagatga gcacgctgtc ggtgccaagc acgaactcag ctgcgtcggg
    18241 gtgcgagtcc aggtgttcgt cgaagtcggt cgccaccgag cgcagcgcgg aatccacgtc
    18301 gaggttgtcg acccgccacc ggatccttcc gtcctctctg gacaccgagc gtgatatgtc
    18361 gggttcaccg ccgaatgtgg ctggcggaat ccatcgccag acgggttttc gcagcagagc
    18421 ggacatctcc cccgggaggc cggaaagtgc tttccgggct tgcagcaaac ggcttgctcc
    18481 gccgtcttcg gcggggcgca cgcagaacag tgcgaatcgc tgctcgggct ccgctcggta
    18541 ggcggcgtcg gtgtggaagc gtgcctcgcc ggcgcgcacg ctgaacgtat cggttgaccc
    18601 ggacttccgc ggtgtcaccg gccagatggc ctgccctccg tcgcgatccg aggccgttcc
    18661 gtaacggctc gcgattcgtt cgaccgcccg gtaatccacg tcggatccat cggtgaaacc
    18721 ggcgccgtcg atcaatgccc aaccttgatt tgttagcgtt tcgagcacgg aggtcatggt
    18781 tgcctttcca tggtccttac gcctgggggc aatcgtgcct gccggacagt acggcccaca
    18841 atggtccatg tgggtggcgc ttcgcttgcg ccacagtccg ttcggccgaa gagagcggtc
    18901 tgacaggcca ggcgtaaaat tccgttcgcg accaagcggc tgacggttct gggatgtaga
    18961 tctgacgatt gttgcgccag atgagtgatg ttgggatcgg gtggtgcggt acttgctgga
    19021 aattgggcag actcgccgac atgacgggat tcgctgagta tcagcgcgaa atcgtccaac
    19081 tcggcgaaga tggagtatcg cttcctttta cgacggatct ggccgcgctg gaggacgccg
    19141 ttcgagccaa ggtgccggcc ggaccgtact ggtacgtggc aggcggtgcc gggacgggtg
    19201 ccactgttcg cgccaaccgc gcggcgttcg agcgttggcg gatcgtgcca aggatgctcc
    19261 gaaacgccga ccgcagagac ctgagcacca cggtgctcgg catgcacctg cctgccccgg
    19321 tgctgctggc acccgtcggc gttcaatcca tactgcaccc ggagtcggaa ctcgcgagca
    19381 cacgtgcggc cgcagaactg ggtcttccat cggtgctttc ctcgtcatcg tcgcggactc
    19441 tcgaagaggt cgcttccgcc ggttgtgacg cgccgaggtg gatgcagttg tactggtcga
    19501 gcgaccgcga gatctgcgcc agcatcctcg accgcggcaa gcgcgccggc ttctccgccc
    19561 tggtggtcac cgtggacacc tgggcccggg gctggcgacc gcacgaaatg gacaggcgct
    19621 actacccggc tgagcaagga atcggcatgg cgatcccgtt ttccgatcct gttttccgat
    19681 ccaggctcgc caagccgccc gaagaggatc tcgccgcggc actccagttg tggcagcgca
    19741 tgcccactga tgccggcaag agctggcagc agttctcctt cctgcgcgat cactggtccg
    19801 gcccgatcgt ggtgaaagga atcctgcatc ccgacgacgc gcgccatgct gtcgcgcgcg
    19861 gggccgacgg gatcgtcgtc tccaaccacg gaggacgcca ggtcgacggt gccgtaggtg
    19921 cgttggagat gctccccgag gtcgtcgacg cggtcggcgc ggaggtagac gtattgttcg
    19981 attccggaat ccggaccggt gcggatgtca tcaaagccct tgccctggga gcgaaagccg
    20041 tgctcgtcgg ccgaccctac gcgtacgggc tcgctcaagc gggcgaggcg ggcgtgcgcc
    20101 acgtgttgcg cagcctgctc gcggacatcg acatcacgct cgggcttgtc gggtaccgca
    20161 gcccggctga gctcgaccga gatgcgctcc gctgaatcac ccggctcccc ggccatacac
    20221 agggttggag aagacacctt gaactttccc gtcagcctcg tcgactgcac gttgcgtgaa
    20281 gt
//
