LOCUS       NZ_CP040605            24808 bp    DNA     circular CON 25-AUG-2024
DEFINITION  Saccharopolyspora sp. ASAGF58 chromosome, complete genome.
ACCESSION   NZ_CP040605
VERSION     NZ_CP040605.1
KEYWORDS    RefSeq.
SOURCE      Saccharopolyspora sp. ASAGF58
  ORGANISM  Saccharopolyspora sp. ASAGF58
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Saccharopolyspora.
REFERENCE   1  (bases 1 to 8045912)
  AUTHORS   Guo,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-APR-2019) Grain Processing Research Group, Academy of
            National Food and Strategic Reserves Administration, Baiwanzhuang,
            Beijing 100037, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 76.15x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012277335.1-RS_2024_08_25
            Annotation Date                   :: 08/25/2024 04:20:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,606
            CDSs (total)                      :: 7,535
            Genes (coding)                    :: 7,265
            CDSs (with protein)               :: 7,265
            Genes (RNA)                       :: 71
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 270
            CDSs (without protein)            :: 270
            Pseudo Genes (ambiguous residues) :: 0 of 270
            Pseudo Genes (frameshifted)       :: 80 of 270
            Pseudo Genes (incomplete)         :: 228 of 270
            Pseudo Genes (internal stop)      :: 14 of 270
            Pseudo Genes (multiple problems)  :: 48 of 270
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:54:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4169860
            Orig. end                         :: 4194668
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040605.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24808
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24808
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24808
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14808](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14808)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            122..646
                     /locus_tag="FDZ84_RS39030"
     CDS             122..646
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015440 - ABC-type peptide transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01727.1"
                     /locus_tag="FDZ84_RS39030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oligopeptide/dipeptide ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_256413763.1"
                     /transl_table=11
                     /translation="MRRYPQQFSGGQRQRIGIARALVMNPKLVIADEAVSALDVSVQAQ
                     VLNLMSDLQRDLGLAYLFISHDLAVVEHVSNRVGVMYLGKLVELAETGALYANPRMPYT
                     EALLSAIPAGEAGGRERIVLSGSLPSPLDPPSGCRFRTRCWKARDVCAVEEPALREVRP
                     GHWAACHFADA"
     gene            725..1282
                     /locus_tag="FDZ84_RS20020"
                     /old_locus_tag="FDZ84_20025"
     CDS             725..1282
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013224.5"
                     /locus_tag="FDZ84_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20025"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_168587158.1"
                     /transl_table=11
                     /translation="MANRDSAAGDRERNDMTEFVLGDSRKADLDAIDLRLLNLLADDAR
                     ASQRKIARELRISAPTVGERIARLEREGVIRGYRAEVDWGALGFPMQVFASIIAASNQA
                     TVLKALHEIREVEQVSVVTGSMDLLARLRVRDPTHLRKVLLEAIWQIPGVVRVETLVSL
                     AETTHKDYLQGMIGVLQGDQES"
     gene            complement(1362..2156)
                     /locus_tag="FDZ84_RS20025"
                     /old_locus_tag="FDZ84_20030"
     CDS             complement(1362..2156)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="FDZ84_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20030"
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_210435009.1"
                     /transl_table=11
                     /translation="MSYVYPNGHPAVEGVSLSVERGESVAVIGQNGAGKTTLVKMMNGL
                     LRPSTGSIEVDGVHTRGRSTADVSRQVGYVFQNPDDQIFHDDVASEIAFGPRRLGFDRE
                     KVIAQVLRAAKLCRIDDQLTENPYNIPFGLRKFVTIASVIAMDPDVIILDEPTAGQDAA
                     ATALLSDLLRTLTNDGKSVVTITHDREFVAENFARTVGMADRRVLADTKTAEAFAEPDL
                     LLAAGLAAPAARKLADRIGLGGSALSMPELVSQLMGRSTAGV"
     gene            2273..2512
                     /locus_tag="FDZ84_RS20030"
                     /old_locus_tag="FDZ84_20035"
     CDS             2273..2512
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FDZ84_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FDZ84_20035"
                     /product="hypothetical protein"
                     /protein_id="WP_168587159.1"
                     /transl_table=11
                     /translation="MSEPRVAGRRDPEGAQVRIRKDLRYGSRGDHATTVQDRYGIGDLG
                     DQIDLVLHEDDSLPGSLQFPDDVEDQDAARGVQL"
     gene            complement(3557..5074)
                     /locus_tag="FDZ84_RS20035"
                     /old_locus_tag="FDZ84_20040"
     CDS             complement(3557..5074)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00924.1"
                     /locus_tag="FDZ84_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20040"
                     /product="peptide MFS transporter"
                     /protein_id="WP_210435010.1"
                     /transl_table=11
                     /translation="MSTTPHQNTTAAGGNPDKASPETSGQSGHSPRRGLWSMAFTELWE
                     RYSFYGLQGILSFYLLYALAAGGLAVAPAVAAGIVGAYGGAVYLSQIFGAWLGDRLVSP
                     QHMVLSGAIVITAGHVVLAFAPGFAGLGIGLVCIVVGTGALKTNITSIVGFVLDQNPDG
                     RYRDAGFSYFYMAINIGAVVGPLTTGLAQNELGFHYGFGLAAIGMVVALVQYLVSMKHL
                     PERARIVNNPLPPNRRPLVVIVGLVFVAAVGSALATGLLRAENLSTVVTVAALLAATAY
                     FLTMTTSSAVTSDERRRILGYLPLFLASGVYFGFLFQKFTAISILITERIDLHIGGWTF
                     PVAWITTVSPLAAVLITPLIARMWNTMGQRQPGPVTKFAIGLTQIGCAYLFLLIISEAT
                     GDAEIPLALILLFMIAAGSSEVFVGPIGLSLATKIGPKKFRSQMVGLNFLTLALGSSLA
                     GLLGQLFTAINNASYFTITAVCGIGIGLALLAGRGPLGRLLGAGLER"
     gene            complement(5071..6510)
                     /locus_tag="FDZ84_RS20040"
                     /old_locus_tag="FDZ84_20045"
     CDS             complement(5071..6510)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013434.5"
                     /locus_tag="FDZ84_RS20040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20045"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_168587160.1"
                     /sec_met_domain="DAO (E-value: 1.2e-53, bitscore: 181.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPYRNGEISHWMATGRTADASAGPARAQADLPDEEQNLVVVGGG
                     LTGLWAAYHAAVENPGMTVTVLEAEEVGYGASGRNGGWLSPLIPGNRAVYAKAARKRGR
                     NGAAAVAAFQQEMDGAVDEILRILDREGIQADQQRGGHLRVATTPAAMKRLEQTYAADL
                     ANGYRAEDLELLDADAVKKRITIRPALGGVLTRTTARVDPAKLVHGLAQAAESKGVRIV
                     EGTRATRIAPGVVTTSRGTVRARTILACLEAYSGQVDGAIRGLGKREVIPVNSSMVVTN
                     QLPTHVWDRIGWQARECLGDAAHTFVYAQRTADDRIAIGGRGTPYAFNSGTPGRGEVDA
                     RTVRTLRERLQLFFPDVQFSIEHAWRGAIGVTRDWCAGITFDPTTRIGVARGFAGHGVT
                     ATHLAAKTLLDRAAGRDTELTRLPWNDHDSGRWEPEPIRWIGVHAMYRLFGVADWWEER
                     RHSQDTSLIARFGSRLAGLSE"
     gene            complement(6554..7126)
                     /locus_tag="FDZ84_RS20045"
                     /old_locus_tag="FDZ84_20050"
     CDS             complement(6554..7126)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF019498.5"
                     /locus_tag="FDZ84_RS20045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20050"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_168587161.1"
                     /transl_table=11
                     /translation="MSKAYPDVRAGTGARLRRRRRALQLTLRDVANQSGLTEGYLSQVE
                     RDQVNASVRTLQRLCGVLKLTVGDLFEQGESTASPVLRFRDTHGMSFGDGATKVKLTPG
                     SFDHLEVLLGHFCPGGSTGVEPYTHGSSEELLLVLSGEVEVWVREQRHQLSALDSIHYH
                     SSDPHRVVEATGSQEARILWALAPPTY"
     gene            complement(7434..9806)
                     /locus_tag="FDZ84_RS20050"
                     /old_locus_tag="FDZ84_20055"
     CDS             complement(7434..9806)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874442.1"
                     /locus_tag="FDZ84_RS20050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20055"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_168587162.1"
                     /transl_table=11
                     /translation="MSTVLQTRVGQLPTELTSFVGRQRLSAEVKKRLSGSRLVTLTGPA
                     GVGKTRLALHVARELQRAFPDGVRLVELAQLQDPGILVNAMTAALELPDQSAREPLTVL
                     VEFLADKRLLILLDNCEHVLAAAAAVLSAVLRSAPGVQVLATSRERVGVAGEQVLSVPP
                     LTVPRLEPSNGGRPLQDDGVGQHEAVTLFEQRAAAVQPAFTVDPDNEAEVAQLCQRLDG
                     LPLAIELAAVRLGAMSVGQILQHLEDRFRFLTTGHRMAPARQQTLRAAVEWSFGLCSPA
                     EQVLWARLSLFAGEFDLEAAEQVCAGAGLAEEDILDAVSGLVEKSVVSPVQGGTATRYR
                     MLETIRQYGREQLAARGEETLLRRRHRDYYLAVAKQADAEWFGPQQRKWWQRFQSQNPN
                     LWAALDFCCTEPGQARTGLLLTGALWFHWIGSGFVRDGRYWLDRLLALSREPSQERARA
                     LWVRGWIAIVQGDLPNAERASQEGIEVADHVGDRAAKAHATHFLGWHAWFCDDTARASE
                     LAEQALAGYRATGQLSTSAPALLSFNLLASVHFARGDFERAGEACAEGRSICERAGEEW
                     MLAWMRWYLGHARRLAGDVQAAEEEALAALRIKRNFNDPLGLALCIEQLGLVAMDRGDA
                     GRAARLFGAVEPLWKLLGSSPLLNASYWLRWHRDGERHARKVLGDQAYEKAYRQGTQLG
                     NDQAVSYALGEQAPATPTLAQVPAADSALPVLTRREQEVAMLVTQGLSNKEIAQALVIS
                     QRTAETHVEHILCKLGVTSRVQIVTWVRDCLTKRSST"
     misc_feature    complement(9159..9161)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11002)
                     /locus_tag="FDZ84_RS20055"
                     /old_locus_tag="FDZ84_20060"
     CDS             complement(10001..11002)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695517.1"
                     /locus_tag="FDZ84_RS20055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20060"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_168587163.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.7e-63, bitscore:
                     213.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASDLLSWRRQILDDELRAAVDRLPGMLRRIAGYHFGWWDADGT
                     PVDGNTGKAVRPALVLLSAEAVGGSGVDALSAAVAVELVHNFSLLHDDVMDADQLRRHR
                     PTAWSVFGIPQAILAGDAMVALANKVLSDRDFPWTATALRWLNESVIELCAGQLADVAF
                     EHRAQVDLAECISMVEGKTASLLGTSCALGALTAGVDADRVELLRRFGIHLGIAFQLVD
                     DLLGIWGDPQVTGKPVGSDLARRKKSLPVIAALASGTAAGAELAAVYAAEDPIRVDRAC
                     ELVELAGGRDWARTRADEEMTAAVACLDAADCVPAARAGLTGLASLVLHRNH"
     misc_feature    complement(10736..10738)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11139..11157
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            complement(11293..12138)
                     /locus_tag="FDZ84_RS20060"
     CDS             complement(11293..12138)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.4"
                     /locus_tag="FDZ84_RS20060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_168587164.1"
                     /sec_met_domain="T1TS (E-value: 5.8e-18, bitscore: 64.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPGERNLKSMLQHIESATNWLQQLDDERSAARKLFMLFYYLVDG
                     HSVRKIDDRLVVNVDLVRNIADSMHRAVEFKTPASSQGSPAKVFADFWERLTSLTPPNE
                     WPVLAGSFRRMADSTVIKYEAIDDGVTMPLDRFIQVRRHVPVMTFLSVERALRGIPVST
                     SGEDAVLAGLVADYIGWTNDLFSAKREIEENFNLVLVGREAWQLPMDKAADRVVGMLEE
                     RRREYARRTGDLGRFSELTASGVVPFYDELIHAATQIYRSSEWYRAAKEIPDAIVRPPR
                     "
     gene            complement(12211..13446)
                     /locus_tag="FDZ84_RS20065"
                     /old_locus_tag="FDZ84_20070"
     CDS             complement(12211..13446)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="FDZ84_RS20065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20070"
                     /product="cytochrome P450"
                     /protein_id="WP_168587165.1"
                     /sec_met_domain="p450 (E-value: 1.3e-19, bitscore: 69.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKSVDFDPFSTHREDPYPYLLSAQETRPVFYSDRLEAWCVTRHS
                     DIERALRDSALFSCRDHNPRPPKTLSPDLLHALETWRGNAPPMGSIDGPEHARIRAVAG
                     RGFTARILNSYEPQIIRVADSLIERMSSRSTFSFISEFAYPFPLSVILSVLGVPEEYHD
                     SCREWTELRISVLLPRETPPAEVQQRCLKGLRDFVAMSRSIVADRLKHPREDLISYMLH
                     SDIRGNRMTADEVVAQIPTFISAGHESTAQALASITYRLLTTPAGWRELAEGSVKSPAL
                     VEEGLRFDGPISGFFRTAKADCEIAGTPIPKGSRIFLAFGAGSRDKEVFPEANKFLTER
                     SNARSHLAFGGGPHHCVGAALARLELSIALDRLAHNFPNLRLVSGQSTHHLPRFPLRAL
                     SDFLVSTDAELP"
     misc_feature    complement(13069..13071)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13513..14808)
                     /locus_tag="FDZ84_RS20070"
                     /old_locus_tag="FDZ84_20075"
     CDS             complement(13513..14808)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="FDZ84_RS20070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20075"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_168587166.1"
                     /sec_met_domain="T2TS (E-value: 1.6e-35, bitscore: 121.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAVPQCHDPVVTELEEWLRVLALGAEKKPAPNLSNTSRTWSGRV
                     LLVESISVIENCPYSDAAHLLDIVGALRGKRVKQWQRTLLAAAEIIADARLGNSISRNA
                     VTDLVAEQRTDGGFCLMPAISAVACIALLAANEQEAARNCLTNLLENQCTDGTWRYLPF
                     DIWDTALMVRALRGCRLFDEKSLAAALSFVERTQSDDGGWACKRGLESDNDTTGAALLA
                     LAGSAAGRRVTSRAVDYLRRVQRDDGLWMTWQSADDVPSPDVTAHVVSAATTHSMTSLD
                     TSRAVRWLVKQYEEAGWSAHWYPTKSYAVREISVAIGIDHKTSRRAAQDLITRQRADGG
                     WPAFDHDSSSSAAATGLALSVLARSKETPDQVLRNAASFLIGNQSDQGTWVGSPFMAGP
                     RPLLNHYPSHTHAFASTGLHDFLKFALGNGKR"
     misc_feature    complement(13531..13533)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(13543..13545)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14089..14091)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14365..14367)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15048..15275)
                     /locus_tag="FDZ84_RS20075"
                     /old_locus_tag="FDZ84_20080"
     CDS             complement(15048..15275)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013628.5"
                     /locus_tag="FDZ84_RS20075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20080"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_246868292.1"
                     /transl_table=11
                     /translation="MTNSELLASWRDAPEAHQPESPDRAALNNVLARLAAAPALVTPSA
                     CDYLRSRLAAVAIGPRMTRLQIFTTTPAEK"
     misc_feature    complement(15258..15260)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15316..15331
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: strong, score: 23.86"
                     /tool="antismash"
     gene            15436..>15528
                     /locus_tag="FDZ84_RS40765"
                     /pseudo=""
     CDS             15436..>15528
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012345.5"
                     /locus_tag="FDZ84_RS40765"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVVAEPFPAELVCTARSIDDGYLVGLRHRNL"
     gene            complement(15610..16995)
                     /locus_tag="FDZ84_RS20085"
                     /old_locus_tag="FDZ84_20090"
     CDS             complement(15610..16995)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (137-422). E-value:
                     4.7e-10. Score: 31.0. Matches aSDomain:
                     nrpspksdomains_FDZ84_RS20085_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695510.1"
                     /locus_tag="FDZ84_RS20085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20090"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_168587167.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.9e-08, bitscore:
                     31.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPIAIDRKSPLSLTVQIRSVIRERIWDGTLHPGVRLPSSRDLAA
                     DLGVSRSVVVQAYEQLIAEGYLRATQGSGTRVATHLPHLGRVAVEQPTGTADARFDLRV
                     DATSTEFFPAREWLKAYQGVVRSIGGPGPWRRPLGVPELRSELAAYLGRSRGVQATAAE
                     VVVTANFDHTFGVLCHILRELGVDHIAVENPGAPWQVRIAQRAGLWVTGVPVDDEGVDV
                     EALARTKARAVLVTPVAQVPTGAVLSPSRREALLRWAVDVDGWVIEHDRDSDLWFGASS
                     GPLALQRGGAERVIYAGSTRGLLGPSLQLGWSVAPEVVTRRLGRAQLGAPDPLTQLAFT
                     HFVSSGLLDQHIRQVRRTYRARRSVLQDAVAEHLPRARLAGVPAGTHAYVRLPAGVDDV
                     RLATVARTRSVLVHPGRHFHFDGRPSAPGVMLGYGAVRRGLLAEAVGVLAAVMAQVTGL
                     LAS"
     aSDomain        complement(15730..16584)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FDZ84_RS20085_Aminotran_1_2.1"
                     /evalue="4.70E-10"
                     /label="FDZ84_RS20085_Aminotran_1_2.1"
                     /locus_tag="FDZ84_RS20085"
                     /protein_end="422"
                     /protein_start="137"
                     /score="31.0"
                     /tool="antismash"
                     /translation="LGVPELRSELAAYLGRSRGVQATAAEVVVTANFDHTFGVLCHILR
                     ELGVDHIAVENPGAPWQVRIAQRAGLWVTGVPVDDEGVDVEALARTKARAVLVTPVAQV
                     PTGAVLSPSRREALLRWAVDVDGWVIEHDRDSDLWFGASSGPLALQRGGAERVIYAGST
                     RGLLGPSLQLGWSVAPEVVTRRLGRAQLGAPDPLTQLAFTHFVSSGLLDQHIRQVRRTY
                     RARRSVLQDAVAEHLPRARLAGVPAGTHAYVRLPAGVDDVRLATVARTRSVLVHPGRHF
                     HFDG"
     misc_feature    complement(16990..16992)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17234..17524
                     /locus_tag="FDZ84_RS20090"
                     /old_locus_tag="FDZ84_20095"
     CDS             17234..17524
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014884.5"
                     /locus_tag="FDZ84_RS20090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20095"
                     /product="hypothetical protein"
                     /protein_id="WP_210435011.1"
                     /transl_table=11
                     /translation="MAEAGDARLAGLLIGLRSKGETVAELDGLVRAMDAHAVKIGVDEP
                     FLDIVGTGGDQAGTVNISTMSAIVAAAAGARISPQRGDHAAVPRGRTRSGP"
     gene            complement(<17792..17938)
                     /locus_tag="FDZ84_RS40770"
                     /old_locus_tag="FDZ84_20100"
                     /pseudo=""
     CDS             complement(<17792..17938)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.5"
                     /locus_tag="FDZ84_RS40770"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20100"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRRSRGRALVDRELYLPASWTGDRQRLAEAGIDDDVEFATKPQLA
                     QRML"
     gene            complement(<17946..18098)
                     /locus_tag="FDZ84_RS40775"
                     /pseudo=""
     CDS             complement(<17946..18098)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024935.5"
                     /locus_tag="FDZ84_RS40775"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEYVLGNLGDRGGIMLADETGFLQKGTKSVGVQRQYSGTAGRIEN
                     CQPGVF"
     gene            19317..19631
                     /locus_tag="FDZ84_RS20100"
                     /old_locus_tag="FDZ84_20110"
     CDS             19317..19631
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011873839.1"
                     /locus_tag="FDZ84_RS20100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20110"
                     /product="hypothetical protein"
                     /protein_id="WP_210435012.1"
                     /transl_table=11
                     /translation="MDVGQRDELVGVAESLERLAAVSTRGDWQVEGLLATRPEVVAHFE
                     GGATEHVAEARAGSARWIAALSPALVEPLAAWLRAAAGQEEIDAAALSFARALRQRLPQ
                     "
     gene            19681..20412
                     /locus_tag="FDZ84_RS20105"
                     /old_locus_tag="FDZ84_20115"
     CDS             19681..20412
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695494.1"
                     /locus_tag="FDZ84_RS20105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20115"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_168587169.1"
                     /transl_table=11
                     /translation="MADSVEFSGQVRLDDLIQSIKKAHGDALDQLTDAVIAAEHLGEVA
                     DHLIGHFVDQARRSGASWTEIGKSMGVSKQAAQKRFVPKGDAAGFDPSQGFGRFTPRAR
                     NVVVLAQNAARDAGNVEILPEHLVLGLLGEPDGIAAQVIVAQGVTLEAVREAVTAALPP
                     AADEAPQILPFDGSARKALELTFREALRLGHNYIGTEHILLALLENEDGNGVLSGLGID
                     KAAAEASITAALAAVVAQMKK"
     misc_feature    19707..19725
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.32"
                     /tool="antismash"
     gene            20511..20969
                     /locus_tag="FDZ84_RS20110"
                     /old_locus_tag="FDZ84_20120"
     CDS             20511..20969
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949547.1"
                     /locus_tag="FDZ84_RS20110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20120"
                     /product="GreA/GreB family elongation factor"
                     /protein_id="WP_168587170.1"
                     /transl_table=11
                     /translation="MGGEESAVGRARLTEEIRTLRARRQQLVDELRQTDDPGDRGDAAQ
                     ELQGGDELVAIDDRIAGLEGLLAGGQPDVGGLAPGTEVSLRLPDGTTQDFRVVAIPEEI
                     PSGAEDTSLTSDSPLGLALAGSHPGETVDFPTPEGRNRVEVISIRPPS"
     misc_feature    complement(20548..20562)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            complement(21100..24699)
                     /locus_tag="FDZ84_RS20115"
                     /old_locus_tag="FDZ84_20125"
     CDS             complement(21100..24699)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010695492.1"
                     /locus_tag="FDZ84_RS20115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FDZ84_20125"
                     /product="indolepyruvate ferredoxin oxidoreductase family
                     protein"
                     /protein_id="WP_256413548.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.1e-05, bitscore:
                     21.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSDGTQNSGAQKPLNRRCLRVDHRFGSRCCAPHPPSVEVASITT
                     RGSATKEFDMAAYTLDDRYLQESGTVYVTGVQALVRLLFDRIRHDRRAGHSTAAFVSGY
                     EGSPLAGFDLELARRSKLLADHDVVHRPGLNEELAATSVMGSQLTEGLGTQRPDGVVGV
                     WYGKAPGLDRASDALRHANLAGANPRGGAVALVGDDPNAKSSTVPAASEAALADLAMPV
                     FFPADSQDLLDFGLHAVELSRASGLWTSLKVVANVADAAGTAVVAPTWNAPAIPAELKP
                     YSHRPSARLLGAELAGLEHSLHNLRLPLAVEYLRRSGVNHVVRSGPADRIGIVAAGKSY
                     LDIRQALRALGLDDADLARYGIRLLKLGAIYPLDPQLVRDFATGLSEIVVVEEKRSFLE
                     TAIKEILYGRPDAPAVHGKKGPDGGTLFTELGELDPDRIAKGLAGRLTAHGEVEPINAW
                     RQRRRRERIAVPLLARTPYFCSGCPHNSSTKVPEGTVVGAGIGCHTMALFMDADQVGDV
                     VGITQMGGEGTQWIGMSPFVGTEHFVQNIGDGTFTHSGSLAVRATVAAGVNITYKLLHN
                     SAVAMTGGQDAVGALPLARLAETLLLEGVAKVIVTSDAPKRLSGKLPRGVEIRHRDDLL
                     RVQEELAAVPGVTVLIHDQECAAEKRRKRRRGKQPTPAQKVLINERVCEGCGDCGAKSN
                     CLSVQPVATEFGRKTQIHQSSCNVDYSCLAGDCPSFLTVVSSGRTARRKISEVSAGELP
                     EPEHGAGDFTVRITGIGGTGVVTVTQILATAAVIDGRQVRTLDQIGLAQKGGAVVSDLK
                     ITAEPVAQAPKLAAGECDLYLGCDLLVAADPVHLAAADAGRTTAVVSTTEVPTGRMVVD
                     TAVSFPVQSGIRSALDDATARAFYLDARGLAEKLFDDDQFANILQLGAAYQAGSLQLPA
                     ESIERAIELNGTAVAANIQAFRRGRQAIADPDALQAEITPPPAKPREPSAAAHRVRALV
                     RAAAGSELARLLDIRIPDLVDYHDEDYARTYAEFVEEVRGRGVDAVTEAVARNLYKLMA
                     YKDEYEVARLSLDEKLLADVEAQFGAGSRFAFRLHPPVLRALGMNRKISLGPWFRHVLR
                     LLRAARKVRGTRLDPFGYAKVRRVERELIDEYRKMIAEALATPDHPALLELAELPDMVR
                     GYEEIKLANVAAYRERQSELRKSLEARPVGAAT"
     misc_feature    complement(24667..24683)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.23"
                     /tool="antismash"
     misc_feature    24765..24779
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
ORIGIN
        1 acccccggat gcgcatggag cggatcgtcg gcgagggcct tgccgtccag gggttggccg
       61 ccgggagcgg gccgcgagcg tggccgaggc gctggaacgc gtcggtctac gccgtgacca
      121 gatgcggcgt tatccgcagc agttcagcgg cggtcagcgg cagcggatcg ggatcgcccg
      181 cgcgctggtg atgaacccga agctggtgat cgccgacgag gcagtctccg cgctggacgt
      241 gtcggtccag gcgcaggtgc tcaatctcat gagtgacctg caacgggatc tgggtctggc
      301 gtatctgttc atctcgcacg acctcgccgt tgtcgagcat gtgagcaacc gcgtcggggt
      361 gatgtatctc gggaaactgg tggagttggc cgagacgggg gcgctctacg cgaacccgcg
      421 catgccctac acggaggcgt tgctctccgc gatcccggca ggcgaggccg gcggccggga
      481 gcggatcgtg ctctcgggaa gtctgcccag cccgcttgac ccgccgagcg gttgccgttt
      541 ccgtactcgc tgttggaagg ctcgggatgt gtgtgctgtc gaagagcccg cgctgcgcga
      601 ggttcggcca ggccattggg ccgcgtgtca cttcgccgat gcatgatcga cgagatcaag
      661 tgcatactcg gcggacgatc gcagctgcga gccgcatgcc gcgcgacatg agggagaggt
      721 tggtatggcg aaccgggatt ccgctgctgg tgaccgggag cgaaacgaca tgaccgagtt
      781 cgtgctgggt gactcccgga aagccgatct cgatgcgatc gatctccggc tgctgaacct
      841 gctcgccgat gacgcccggg ccagccagcg caagatcgcc cgggagttgc gtatctctgc
      901 tccaaccgtc ggtgagcgca ttgcgcggct cgaacgcgaa ggcgtgatcc gcggttaccg
      961 ggcggaggtg gactggggtg cgctgggctt cccgatgcag gtgttcgcct ccatcatcgc
     1021 tgcctccaac caggcgaccg tgctgaaggc gctgcacgag atccgggagg tcgagcaggt
     1081 gtccgtggtc accggctcga tggatctgct ggcgcgactg cgggtgcgag acccaacgca
     1141 cctgcgcaag gttctgctgg aggcgatctg gcagattccc ggtgtggttc gggtcgaaac
     1201 cctggtgagc cttgccgaga cgacccataa ggactacctg caggggatga tcggcgtgct
     1261 gcaaggggat caggagtcct gagcccgggg tgtgcgcggt gcaggaccaa ggcccgtgag
     1321 cgtttttcgg tgctatggca cccaaaatca ctcacggcca ttcagactcc ggccgtcgac
     1381 cgccccatta gctgggaaac cagttcgggc atggacaggg cggagccgcc caggccgata
     1441 cggtcagcga gtttgcgggc ggcgggggcg gccaggcccg cggcgaggag aaggtcgggc
     1501 tcggcgaatg cctccgcggt cttggtgtcc gcgagcaccc gccgatccgc catcccgaca
     1561 gtccgggcga aattctccgc gacgaactcc ctgtcgtggg tgatcgtgac gaccgattta
     1621 ccgtcgttcg tcagggtgcg cagcaggtcc gacagcaggg cagtcgccgc ggcatcctgg
     1681 cctgcggtgg gctcgtcgag gatgatgacg tcagggtcca tcgcaatgac cgaggcaatc
     1741 gtgacgaact tccgcaggcc gaaagggatg ttgtacgggt tctcggtcag ttggtcgtcg
     1801 atccggcaga gcttggcggc ccgcagcacc tgcgcgatca ccttctcgcg gtcgaagccg
     1861 aggcgcctgg gcccgaacgc gatctcgctc gcgacgtcat cgtggaagat ctggtcgtcc
     1921 ggattctgga agacgtaccc cacctgccgg gagacgtcgg ccgtggaacg tccccgggtg
     1981 tgcacgccgt cgacctcaat gctcccggtc gacggccgga gcaggccgtt catcatcttg
     2041 accaacgtgg tcttgccggc gccgttctgg ccgatcacgg ccacggactc gccgcgctcg
     2101 acggagagcg agaccccttc gacggccgga tggccattcg ggtagacgta ggacacgccg
     2161 gtgacggtaa gcaggctaat cggacggtct ccagccagtc gtgcagcgcg tctgccgcag
     2221 cttcgagggt ggtcggtacg gtggaaagcg gcccgccggc ctccgccatc aggtgtccga
     2281 accgcgcgta gctgggcggc gcgaccccga aggtgctcag gtcaggatcc gcaaggacct
     2341 ccgctacggc tccagaggcg accacgcgac caccgtccag gaccgatacg gcatcggcga
     2401 tctcggcgat cagatcgatc ttgtgctcca cgaggacgac agtcttcccg gcagccttca
     2461 gttcccggac gatgtcgaag atcaggacgc tgcccgcggg gtccagctgt gaggtcggct
     2521 cgttgcgcgt ggtcgacccg gattcgcaga gtgcggggcc agtgcggcca gccgagactg
     2581 cctcgatgac ttatcggaac acgccgagcc cgaaccgtgg tccccgccgc cgtggtggac
     2641 ggtgtgacag cgggcgggac ggtctcggcg attcgggcct tcgccgccgt ctgcggcgat
     2701 catggcgttc gaaggtcaat gtgccgggtt agctccagtt acgatagtgc cttaacggac
     2761 gcattcttcg cgacgctcaa acgcgaacta ctccacaatg gacgatctgg cgtggagtag
     2821 tgaagccgag gccagacagc aggtctttcg ctggatcgcc ttctgcaacc accgacgccg
     2881 acgggggctg cgatccccac cggagccccc gatgaggacc gcgtgggctt gaacagcgtt
     2941 gtgctgcgtt gaacggtacc gagctacacg gacttgacct tccttttggc tcttctgctt
     3001 cttccgtggg ctaggcgagt ccggggattg acacgtctac cgggacatgg caccggtaag
     3061 aaccggcatt gtcactcacg acgggccggg tatcggtcgt gagtggtggt tccggtaaga
     3121 gccggcattg tcactcacga cgggccgggt atcggtcgtg agtggtggtt ccggtaagag
     3181 ccggcattgt cactcacgac cggacggatg ctcgtcgtga gtgactgttc cgttccaaaa
     3241 acacccgggt ggtcccgaga tccagcgccc gccaccgagg acgcccacca cggcacgcca
     3301 ttggccttcg gcacgccgtt ctacgtccct tcggttcctg actctggaca agccagaaac
     3361 ccagaccaag caacggcgtg cccccgtctc tgggcccaaa aacccagctc acaccaccca
     3421 cggaaacgtc acaagagccc ttcttttctg gtgttcttgc agctcactgt ctcttgtgga
     3481 catgacttgc gtataaaagg tcgcagcagg gtgttgcgtc atccaagtgc gttctgctgt
     3541 cacttcttgg accgggtcag cgttccagcc ctgcgcccag gagacgtccc agcggtccgc
     3601 gcccggcgag gagtgctagg ccgattccga tgccgcacac ggcggtgatg gtgaagtagg
     3661 aggcgttgtt gatcgcggtg aacagctggc cgagcaggcc tgccagggac gagcccaacg
     3721 cgagcgtgag gaagttaagg ccgaccattt gtgaccggaa cttcttgggg ccgatcttcg
     3781 tggccaggga cagcccgatc gggccgacga agacttctga ggaaccggcc gcgatcatga
     3841 acaggagaat gagggccagt gggatctcgg cgtctccggt tgcctcggag atgatgagca
     3901 ggaacaggta ggcgcagccg atctgggtca gcccgatggc gaacttggtc accggcccgg
     3961 gttgccgctg tcccatggtg ttccacatcc gggcgatgag cggggtgatg aggacggccg
     4021 ccagcgggct gacggtcgtg atccaggcga ccgggaacgt ccatccgccg atgtgcaggt
     4081 cgatgcgttc ggtgatgagg atcgatatcg cggtgaactt ctggaacagg aaaccgaagt
     4141 acacgccgga ggccaggaag aggggaagat agccgaggat gcgccggcgc tcgtcgctgg
     4201 tgacggccga cgaggtggtc atagtgagga agtacgcggt cgcagccagc agcgcggcga
     4261 cggtcaccac ggtggacagg ttctccgccc ggagcagtcc ggtggcgagc gccgagccca
     4321 cggcggcgac gaagacgagg cccacgatga cgacgagcgg gcggcggttc gggggcaggg
     4381 ggttgttgac gatccgggca cgctcgggca ggtgcttcat cgaaacgagg tactggacca
     4441 gcgccaccac catgccgata gctgccagcc cgaatccgta gtggaaaccc agttcgttct
     4501 gggcgaggcc ggtggtgagc ggaccgacca ccgcaccgat gttgatggcc atgtagaagt
     4561 aggagaaacc ggcatcccga taacgcccgt cggggttctg atccagcacg aagccgacga
     4621 tcgaggtgat gttcgtcttc agcgccccgg tgccgacaac gatgcacacc agaccgattc
     4681 ccagcccggc gaagccgggc gcgaaggcga gcaccacgtg cccggcggtg atgacgatgg
     4741 cgccggacag caccatgtgc tgcgggctga cgagccgatc gcccagccag gccccgaaga
     4801 tctgggacag gtacacggcg ccgccgtagg caccgacgat gcccgccgcg acggccgggg
     4861 ccacggcaag accgccggct gccagcgcgt aaagcaggta gaacgaaagg atgccctgga
     4921 ggccgtaaaa ggagtagcgc tcccacaact cagtgaaggc catactccac aggccgcgcc
     4981 ggggcgaatg ccctgactgc cctgacgttt cgggcgatgc cttgtcggga ttgccgcctg
     5041 cagccgtcgt gttctggtgc ggtgtggtgc tcattcgcta agtcctgcca gtcgcgagcc
     5101 gaaacgagca atgagagaag tgtcctggga gtgcctgcgt tcttcccacc agtcggcgac
     5161 gccgaagagc cggtacatgg cgtgaacccc gatccagcgg atgggttcag gctcccagcg
     5221 cccggagtcg tgatcgttcc acggtagccg agtcagctca gtatcacgcc cggccgcccg
     5281 gtccaagagg gtcttggccg cgagatgggt ggcggtgacg ccgtgcccgg cgaaaccgcg
     5341 cgcgacgccg attctggtgg ttggatcgaa cgtgatcccg gcgcaccagt cgcgggtcac
     5401 gccgatggcg ccccgccagg cgtgttcaat gctgaactgc acatctggga agaagagttg
     5461 gagccgttca cgcagggttc ttacggtgcg ggcgtccacc tcgcctcggc cgggagtgcc
     5521 ggagttgaag gcgtaaggcg taccgcggcc gccgatggcg atgcggtcgt cggcggtgcg
     5581 ctgcgcatag acgaaggtgt gcgcggcatc gcccagacat tcccgtgcct gccagccgat
     5641 cctgtcccac acatgagttg ggagctggtt ggtgacgacc atggaggagt tgacggggat
     5701 gacctcgcgc ttgccgagac cgcggatggc accgtcaacc tgcccggaat aggcttccag
     5761 gcaagcaaga atggtcctgg cccgcacggt cccgcgtgac gtggtcacaa caccgggcgc
     5821 gatacgggtg gcgcgtgtgc cctccacgat gcgtacgccc ttgctttccg ctgcctgtgc
     5881 aaggccgtga acgagcttgg ctggatcgac gcgcgccgtg gtgcgggtca acacgccgcc
     5941 tagcgccggc cggatggtga tccgcttttt cacggcgtca gcatcaagta gttcgaggtc
     6001 ctcggcacgg tagccgttcg cgagatccgc ggcgtaggtc tgttcgaggc gtttcatcgc
     6061 agccggggtc gtggccacgc gcaggtgccc accccgctgc tggtccgcct ggatgccttc
     6121 ccgatccagg atgcggagta tttcgtcgac ggcgccgtcc atctcttgct ggaaggcggc
     6181 gacggcagcg gcgccattgc gcccccgctt gcgcgcagcc ttggcataca cggcgcgatt
     6241 gcccgggatg agcggcgaga gccagccgcc attacggccg gaggcaccgt atccgacctc
     6301 ctccgcctcg agaacggtca cggtcatccc ggggttctcc accgccgcgt gatacgcggc
     6361 ccagagccca gtcaagccac cgcccacaac gacgaggttc tgctcctcgt cgggcaggtc
     6421 ggcttgagcc cgcgccgggc ccgccgacgc atccgcggtg cgaccggtcg ccatccagtg
     6481 cgaaatctct ccgttgcgat acggggacat cagtaactcc aacaagggca cgccagtgac
     6541 taggtaggga ggttcaatag gtggggggtg ccaaagccca caggattcga gcctcttgtg
     6601 agccggtggc ctcgacaacc cggtgcgggt cgctgctgtg atagtgaatc gagtccaggg
     6661 cggaaagctg gtggcgctgc tcgcggaccc acacctccac ctcaccggac aggaccagca
     6721 gcagttcttc ggagctgccg tgggtgtagg gctccacgcc ggtggaacca ccaggacaga
     6781 agtgcccgag cagtacctcc aggtgatcga aggatcctgg ggtgagcttg accttcgtgg
     6841 cgccgtcacc gaatgacatg ccgtgggtgt cgcggaaccg cagcaccggg ctggccgtgg
     6901 actcgccctg ctcgaagaga tcaccgaccg tgagtttcag gaccccgcac agccgctgaa
     6961 gggtgcgtac gctcgcgttg acctggtcgc gctcgacctg agacaggtag ccctcggtga
     7021 gaccggactg gttggccacg tctctcagcg tcagctgaag agctcgtcta cgccgacgca
     7081 ggcgagcacc ggtacccgct cggacgtcgg gatatgcctt cgacatggcg ggaaacctaa
     7141 caggacattg atatgatcac aatgcctttt ggcctcatca aatttttctt tgatccaccg
     7201 ggctggtgca ggcgggttgt gagtgggttg agacgccggc tgtcactgaa ggggctctgt
     7261 agagctctgc cgctctccgc acgccaggat gggctccccc ggctgtcgcc agggctgcca
     7321 tgaaggtccg ccgctcgccg ttccccaagg acaacagtga gtgcttcgcg gagctgcgtg
     7381 ttctctctgc aacagggcga cggtcgggtc ggtggcggtg atcgtggcgc cgatcaggtt
     7441 gatgatcgtt tcgtcagaca atccctgacc caggtgacga tctgcacccg agaggtgact
     7501 ccgagcttgc agagaatgtg ctcgacatgc gtttcggcgg tgcgctgcga gatcaccaac
     7561 gcttgggcaa tctccttgtt cgacagccct tgcgtgacca gcatggcgac ctcctgctcc
     7621 cgccgggtca gtactggcaa agcggaatcc gcggcaggaa cctgggctag cgtcggagtc
     7681 gccggagcct gttcaccgag cgcgtaggac accgcctggt cattgcctag ctgcgtgccc
     7741 tgccgataag ccttttcgta cgcctgatca cccaggactt tcctggcgtg gcgctcaccg
     7801 tcgcggtgcc accgcaacca ataactcgcg ttgagcaggg ggctgctgcc caggagcttc
     7861 cacagcggct cgacggcacc gaacagtcga gcggcccgcc ccgcgtcacc gcgatccatc
     7921 gccaccagac ccagctgctc gatgcacagc gccaggccca gcgggtcatt gaagttgcgc
     7981 tttatgcgaa gggcggccag tgcctcctct tctgctgcct gaacgtcgcc ggcgagccgc
     8041 cgagcatgcc ccaggtacca gcgcatccag gccagcatcc actcctcgcc ggcccgctca
     8101 cagatcgacc ggccttccgc acaggcctcg ccggcacgtt cgaagtcgcc acgtgcgaaa
     8161 tgcacgctgg ccagaaggtt gaaggagagc agggcggggg cggaagtgct gagctgcccc
     8221 gttgcgcgat acccggccag cgcctgctcc gccagctcgg acgcccgcgc cgtatcatcg
     8281 caaaaccatg catgccatcc caggaaatgg gtagcgtggg ccttggccgc ccgatcgccc
     8341 acgtggtcgg ccacctcgat gccctcctgc gatgcacgct ctgcattagg gaggtctccc
     8401 tggacaatgg cgatccaacc gcgcacccac agggccctcg cccgttcctg gctcggttcc
     8461 cgcgacagcg ccagcagccg gtccagccag taccggccgt cccgaacgaa accgctgccg
     8521 atccagtgga accacaatgc accggtgagc agcagtcctg tcctggcctg accgggctcg
     8581 gtgcagcaga agtccagcgc cgcccacagg ttcgggttct ggctctggaa ccgctgccac
     8641 catttccgct gctgcggccc gaaccattcc gcgtcggcct gcttggccac cgctaggtag
     8701 tagtcccggt gccgacgccg cagcagcgtc tcctcgccac gggcggccag ctgctctcgc
     8761 ccatactggc ggatggtctc cagcatccgg taccgcgtcg cggtaccgcc ctgcaccggg
     8821 gacaccactg acttttccac cagtccggac acggcgtcga ggatgtcctc ctcggccagt
     8881 ccggcaccgg cacacacctg ctcggccgcc tcgagatcga actcacccgc gaacaacgac
     8941 agccgagccc acaacacctg ctcggccggc gagcacaggc cgaaactcca ttccaccgct
     9001 gcccgcaacg tctgctgtcg ggcgggcgcc atccggtgcc cggtggtgag aaaccggaac
     9061 cggtcctcca aatgttgcag gatctggcca accgacatgg cccccagccg caccgcggcg
     9121 agttcaatcg ccaacgggag cccgtccagc cgttggcata actgcgccac ctcggcctcg
     9181 ttgtccgggt ccaccgtgaa cgccggctgc acggccgccg cccgctgctc gaacagcgtc
     9241 actgcctcat gctgaccgac gccgtcgtcc tgcaacggtc gcccaccgtt cgacggctcc
     9301 agccggggta ccgtcagcgg gggcaccgaa agcacctgct ccccagcaac gcccactcgt
     9361 tcccgactcg tagccagcac ctgaaccccc ggcgccgacc gcaacaccgc actcagcacc
     9421 gccgcagctg ccgccagcac gtgctcacag ttgtccagca ggatcagcaa tcgcttgtcc
     9481 gccaggaact ccaccaggac ggtcagcggc tcccgcgccg actgatccgg caactccagg
     9541 gccgccgtca tcgcgttcac cagtatcccg gggtcctgca gctgggccag ctccaccagc
     9601 cgcacgccat ccgggaacgc ccgttgcagc tcccgggcca cgtgcagtgc cagccgggtc
     9661 ttgcccaccc cggccggacc ggtcaacgtc accaaccgtg accccgacag ccgcttcttc
     9721 acctcagcag acagccgctg ccgacctaca aagctcgtca gttcggtggg aagctgcccg
     9781 acacgggtct ggagcacagt actcatcgca gtcctcgata ccgagcttac gagggctacg
     9841 cagtcacggc cagcgccgtg accgcctgcg cgcgccctgt tgatcatggt ccgacaggct
     9901 ggagcggtat gtggctgagc gggcgcgagc gcgtgagctg gatgccgatg aggcaaccgg
     9961 ctgttgcaca gagccgccgg tgttccggta catgatctac tcagtggttg cggtgcagga
    10021 caaggctggc aaggccggtc agaccagcgc gggcggcggg tacgcagtcc gcggcgtcca
    10081 gacaagcaac ggccgccgtc atttcctcgt ccgcacgggt acgcgcccag tcacggcccc
    10141 cggccaattc caccagctca caagctcgat cgacccggat cgggtcctcg gccgcataaa
    10201 ctgcggccag ctccgcgccc gcagctgtgc cggaggccag tgccgcaatg accggcagcg
    10261 acttctttcg ccgcgccaaa tccgatccca ccggcttgcc ggtcacctgt ggatcgcccc
    10321 agatccccaa caggtcgtcc accagctgga acgcgatccc gaggtggatg ccgaatcggc
    10381 gaagcagctc cacccgatcg gcgtcaacac cggcggtgag tgcgcccagg gcgcacgacg
    10441 tgcctagcag ggacgcggtc ttaccttcga ccatgctgat gcactcggcc agatctacct
    10501 gagcacggtg ttcgaaggcc acgtcggcga gctgtccggc acacagctcg atcacggatt
    10561 cgttgagcca gcgcagcgcc gtcgccgtcc acggaaagtc ccgatcggac aacactttat
    10621 tggccagcgc gaccattgcg tccccagcca ggatcgcctg cgggatgccg aacaccgacc
    10681 aggcagtcgg tcgatgcctg cgcagctggt cggcatccat cacatcgtcg tgcagtaagg
    10741 agaagttgtg caccaactcc accgccaccg cagctgacag cgcgtcgacg cccgatccgc
    10801 ccaccgcctc ggccgacagg agtaccagcg caggacgcac ggccttgcct gtattgccat
    10861 cgaccggcgt tccgtcggcg tcccaccacc cgaagtggta tccggcgatc cggcgaagca
    10921 tgccaggcag gcggtcgacg gctgcacgca actcgtcgtc caagatctgc cgtcgccacg
    10981 acaataggtc agatgccgtc atcgcgtccc tacctctcag gtgtggatgt gatctggtca
    11041 ttcgtgggac cggagggacc aggtgctccg ggtgtggctg tcagttcggt gccgttggat
    11101 ggctgaagga aatcgggtca gccggctgcg ggcccaattg ctggatatct tccccgcgct
    11161 ggacctgacc gaccgggccc ggtcttgctg ctgaccggct accagacacc ggccgcgatc
    11221 cgccgcgccg gcgtcaaacg tgtcgaggac tgcctcatcc gcgaccgcag tgccaccaag
    11281 ccacgccacc cgtcaccgcg gcggcctgac aatcgcatca ggtatctcct tcgctgcgcg
    11341 ataccattcg gaggagcgat atatctgcgt ggctgcgtgg atgagttcat cgtagaacgg
    11401 cactacaccc gaagctgtca actcagaaaa tcgaccgaga tccccggttc tcctcgcata
    11461 ttcacgccgt cgctcctcga gcataccaac gacacggtct gccgctttgt ccatcggaag
    11521 ctgccacgct tcacggccga ccagtacgag gttgaaattt tcctcgatct ctcttttcgc
    11581 ggagaaaagg tcattggtcc atccgatgta atcggctacc aggccggcaa gaaccgcgtc
    11641 ttctccggac gtcgaaactg gaattccgcg caacgcgcgc tcgacgctaa gaaaggtcat
    11701 taccggaaca tggcggcgta cctggataaa tctatcaagt ggcatcgtga cgccgtcgtc
    11761 gatagcttcg tatttgatca ccgtggaatc agccatgcgt cgaaaggaac cggcaagaac
    11821 aggccactcg tttggcgggg tcagagatgt caaacgttcc caaaaatcag caaaaacctt
    11881 ggcgggtgat ccttgtgatg aggctggggt tttgaactca acggcacgat gcatgctgtc
    11941 tgcaatgttg cgcaccagat cgacgttgac caccagtctg tcgtcaattt ttctgacgga
    12001 atggccgtct acgaggtaat aaaatagcat gaagagcttt cgtgccgccg accgttcgtc
    12061 atcaagctgc tgcagccagt ttgtagcaga ttcgatgtgc tgcagcattg atttcagatt
    12121 ccgttcgccc ggagccattt ctctcccttg gctgctatat tgtcattttt ggaggcgtga
    12181 acccgaacga atgtcatgcc ggctagtggc ttacggcaat tcggcatcgg tagataccag
    12241 aaaatcactc aaagcccgca acggaaacct aggcagatga tgagtgcttt gtccggagac
    12301 caagcggaga ttcggaaaat tatgtgcaag cctgtcgagt gcgatggaaa gttccagtcg
    12361 agcgagtgcg gcacccacgc agtggtgcgg gccaccaccg aaggctaggt gggaccgagc
    12421 gttcgaccgc tcggtcagga atttattggc ctcggggaaa acctctttgt cgcggcttcc
    12481 tgcgccgaac gccaagaata ttctagaccc cttagggata ggagttccgg ctatttcgca
    12541 atcagctttc gcggtccgaa aaaaaccgct gatcgggcca tcgaaccgga gaccttcctc
    12601 aaccaaggct ggcgacttca cggaaccctc agccaactca cgccagccgg ctggcgtggt
    12661 aagcagccta tatgtgatag atgcgagagc ctgtgcggtt gactcatgcc ccgcggaaat
    12721 aaacgtcgga atctgcgcca ccacttcatc agccgtcatc ctgttcccgc ggatatcgct
    12781 gtgcagcatg tagctgatga gatcttcgcg cggatgcttc aaacggtccg ccactatact
    12841 acggctcata gcgacaaagt cgcgcaaccc cttgagacat ctctgttgca cctcggcggg
    12901 gggagtctcc cgagggagta gtaccgaaat acgcagttcc gtccattctc ggcacgaatc
    12961 atggtattct tccggaacgc cgagaacgga caagatcaca gacaacggaa agggatacgc
    13021 aaattctgaa ataaagctga aagtcgacct gctgctcatg cgctcaatta aggagtcggc
    13081 gacccggatg atctggggct cgtaggagtt gagtatacgc gcggtgaagc cgcggcccgc
    13141 cacggcgcgg attctggcat gttcgggacc atcgatggac cccataggag gcgcgttgcc
    13201 acgccaggtc tccaaggcgt gaagcaaatc aggagacagt gttttcggcg ggcgagggtt
    13261 gtgatcacga cacgagaaga gagcgctatc ccgaagtgcc cgctcaatgt ccgaatgcct
    13321 ggtgacacac cacgcttcaa ggcgatcgga atagaacacc gggcgcgtct cttgagcgga
    13381 caagagataa ggataaggat cctcccggtg agtagaaaag ggatcgaaat cgacagattt
    13441 aggcacccgt agccccttat tggtcaaatc gctactagta tcgcattcta tcgtcagagt
    13501 tgcctcaacg catcatctct tgccgttccc taatgcgaac tttaagaaat cgtggagtcc
    13561 ggtggaggcg aacgcgtgag tgtgtgacgg ataatggttc agaagtggcc gagggcctgc
    13621 cataaacgga gagccaaccc aggtgccttg atcgctctga ttgcctatga gaaaacttgc
    13681 cgcgttgcgc agcacttggt ctggtgtttc tttcgatctg gcaagtaccg agagggcaag
    13741 gccagtcgcg gccgcagacg aactggagtc gtgatcaaag gcaggccatc ccccgtcggc
    13801 acgctgtcgg gtgatcagat cttgggccgc gcgacggctg gtcttgtggt cgatgccgat
    13861 agcaacgcta atctcccgca ccgcatagct ttttgtcgga taccaatgag cggaccaccc
    13921 ggcttcttcg tactgcttaa ccagccatcg cacagcccgc gaagtatcga gggaggtcat
    13981 ggagtgggtg gtcgccgcag aaacgacgtg agccgtcacg tcaggagacg ggacatcgtc
    14041 cgcggactgc caggtcatcc acaatccatc atcacgttga acgcgacgta agtagtccac
    14101 agcgcggctt gttactcgac gccccgctgc gcttcccgct agcgccagga gcgcggcgcc
    14161 agttgtatcg ttatctgatt caagacccct tttgcatgcc cagccgccat catcggattg
    14221 agttcgttca acgaagctca acgcggcggc caaggatttt tcatcgaata gtcggcaccc
    14281 gcgcagggcg cgaaccatga gcgcggtatc ccagatatca aatggaagat aacgccatgt
    14341 tccgtcagtg cattggtttt caagtaaatt tgtaaggcaa ttccgggccg cctcctgctc
    14401 gttcgcagcg agcagcgcta tgcatgcaac cgcggatatc gcgggcatga ggcaaaatcc
    14461 accatcagtc cgttgttcag cgacaagatc ggtcactgca ttcctggaga tcgagtttcc
    14521 caggcgggcg tcagcaataa tctccgccgc tgccagcagg gtcctctgcc attgcttgac
    14581 cctttttccg cgaagggctc cgacgatgtc gaggaggtgc gccgcatccg aatatgggca
    14641 attttcgatt acggagatcg attcgaccaa cagaacccgt cccgaccatg ttcggctagt
    14701 gttcgacagg ttgggagctg gcttcttttc ggcgccaagc gccagcacgc gcagccattc
    14761 ctctagctct gtcacaacgg ggtcgtggca ctgcggcacc gcgttcatga gccatttccg
    14821 tgcgcgctcg accgctatgg acgctccgct ccctgccttt gccaggcaga gagaaacgat
    14881 agcggtgtcg aatattctgg gatcagacgg agtctcccaa tacccgtctc ggtgctgagt
    14941 gctgcaggca aaccgcacag cagcctgaag tgaccgtttc gtttcttcct tcaagtcagg
    15001 agcgaaccgg tttgcttctc ggaatgaacc gttcggcact gtagtcctca tttttcagca
    15061 ggagtggtag taaaaatctg caaacgagtc attcgcgggc cgattgccac cgcggcaagt
    15121 ctggaccgca gatagtcgca tgcgcttggg gtgaccaatg ccggcgcggc ggccagcctg
    15181 gcgagcacgt tgttcagggc agcgcggtcc ggcgactccg gttggtgcgc ttcgggcgcg
    15241 tcacgccacg aggcgagtaa ctcggaattc gtcatgatcg cagaccacca caaactccgc
    15301 ctggcgtgca atgaattgac cgagtggtcc ggttggcagg gcatcgattg gtctggctaa
    15361 ccgcgactcg ggcttggcgg cctcggcgta tacgccgacc tacccgaccg gtgcacggtc
    15421 acccggtatc actcgatcgt cgtcgccgag ccgtttccgg cggaactcgt ctgcacggca
    15481 cggtcgatcg acgacggtta tctggtgggt ttgcgtcacc ggaatctgcc tgtcgagggt
    15541 gcgcagttcc acccggagag catcgccacc ccgatggcac gacgatggtc gcgaacttcc
    15601 tggccggcgt cacgacgcaa gcagcccggt gacctgagcc atcacggcgg cgagcacacc
    15661 gacggcctcc gcgagcaggc cacgccgcac cgcgccgtaa ccgagcatca ccccgggcgc
    15721 ggacggccgg ccgtcgaaat ggaagtgcct gccaggatgt acgagaaccg acctcgtccg
    15781 cgcgacggtt gccagccgga cgtcgtcgac tccggcaggc aaccggacgt aggcgtgcgt
    15841 gccggcgggt acgccggcca gccgggccct cggcaggtgt tctgcgacgg cgtcctgcag
    15901 cactgaacgc cgcgcccggt aggtgcgccg gacctgccgg atgtgctggt ccagcaagcc
    15961 ggacgagacg aagtgggtga acgccagctg ggtgagcggg tccggagcgc ccaactgcgc
    16021 ccggcccagc cgacgcgtca ctacctcggg cgccactgac cagccgagct gcaagctcgg
    16081 accgagcagg ccacgggtcg accccgcgta gatcacccgt tccgccccac cccgctgcag
    16141 ggcgagcggg ccactgctgg cgccgaacca gaggtcactg tcgcggtcgt gttctatcac
    16201 ccagccgtcc acgtcaacgg cccagcgcaa cagcgcctcc cgccggctag gcgaaagcac
    16261 ggcccccgtc ggtacctgcg ccaccggcgt gaccaggaca gcgcgcgcct tggtccgcgc
    16321 gagcgcttcg acgtcgacgc cctcatcgtc cacgggcact ccggtgaccc acaggcccgc
    16381 ccgctgggcg atcctgacct gccagggtgc accgggattc tccacggcga tgtggtcgac
    16441 accgagctcg cgaaggatgt ggcacaacac gccgaaggtg tggtcgaaat tcgcggtgac
    16501 gacgacctcg gcggcggtcg cctggacccc ccgcgaacgg ccgaggtacg ccgcgagctc
    16561 ggaacggagc tccggaacac cgagtgggcg ccgccagggg ccgggcccac cgatcgatcg
    16621 aaccacaccc tggtatgcct tcagccattc acgcgcgggg aagaactccg tgctggtcgc
    16681 gtcgacacgc aggtcgaagc gggcgtccgc ggtcccggtc ggctgctcga ccgcaacccg
    16741 gccgaggtgg ggcagatgtg tcgccaccct ggttcccgac ccctgagtgg ccctgaggta
    16801 gccctcggcg atcaactgtt cgtaggcttg gaccacgacg ctgcgcgaaa ccccgaggtc
    16861 tgcagcgaga tcgcggctcg atggcaaccg gacacccggg tgcagggtgc cgtcccatat
    16921 tcgttcgcgg atgactgacc gaatctgaac ggtcaaggac aacggcgact tccggtcgat
    16981 ggcgatcggt aacattcttc ccctcttcag cgcggaaatg gcccggccgg cagcggcatc
    17041 taatggtctt ggtcagcgcc tccgcagact ggaacgctga acacgaaata acagcggagg
    17101 agcagcgatg accggccagg cacccgtact cgacacgatt cggaaaaaag ttgggcggag
    17161 attctttcgg cgctcacgga cggccaggac ctcaccgaga gcgatacgga gtgggccatg
    17221 ggcgaggtca tgcgtggcgg aggccggcga tgccaggctg gccggtctgc tgattggcct
    17281 gcggtccaag ggagagaccg tcgctgagct cgacgggctg gttcgcgcca tggacgcgca
    17341 cgcggtcaag atcggtgtcg acgaaccgtt cctggacatc gtcggtaccg gcggagacca
    17401 agccggcacg gtgaacatct ccaccatgtc ggcgatcgtc gccgcggcag cgggtgcgcg
    17461 gatcagccca caacgcggag atcacgctgc ggttcctcga gggcgaacgc ggtccggtcc
    17521 gtgaggccgt cctgctgtcc gccgcagcgg gacttgccgc ggcctcgctc gacgccgcgc
    17581 ccatcacgga gcggttgggt ggtgcggtcc gtgcgagttc gtcgggtcga atccgtccgg
    17641 gcggggtgtc gaaacgctga tcgcaggaga tggccatgac gtacaggtcg cgggattggc
    17701 ggccacgtcc gcaatccagg attgtcgccg taggcctcat ccgtggtgaa ccagccgatg
    17761 ccggcacccg catcggagtc cagcaggtgt ccagcatgcg ctgcgccagt tggggtttgg
    17821 tcgcgaactc gacgtcatcg tcgatccccg cctcggccag gcgttgacgg tcgcccgtcc
    17881 acgacgccgg caaatacagt tcccggtcga ccaacgcccg accccttgac cgacgcattg
    17941 gtcaagaaca cgcccggctg acagttctcg atccgcccgg ccgtacccga gtactggcgc
    18001 tggacaccga cggatttggt gcctttctgc agaaaacccg tctcatcagc gagcatgatc
    18061 ccgccgcgat caccaaggtt gccgagtacg tactccaggg atcatcacgc atctcaccgg
    18121 cgttccagcg gtagaagtcc ggcaaccgct gcaggccgtc ggaggtaacg cccccggctt
    18181 gctcggccag cccccacgag ttcttccgct gcaacccgaa gccaaccccg gcacatactc
    18241 acctggcacg gcgacgcgag tccgcctgcg cgaaatccgc tgccatcgag aacggcccct
    18301 cagcccggcc tgtcaccgag cgagccgatc accggcccgc acttcgatgc cgagatcagt
    18361 tccgtgctca ccaaaggtga cagccaccgg cccgccgaag tgatgccagt agcgctcact
    18421 tcttgcgggc gcgcatccaa aatcctgtga cgttgtgtgc cacaggattt cgtggacctg
    18481 cttccccagt tgacactatg ggtcagacag ccggagtcgg cactgggtcg acgctcatgc
    18541 gtgggccgag aatccgtatg tgatgatgtt tccgccgcgg cttggacgga aattgccgct
    18601 ctggatccag aacgtggacg ggctgcgggt gccgaagtcg ttgatcggct cggcggcggt
    18661 gccggaccca aaaccagtga acttctggca ctgaccactg ttcactgctg actggtggcg
    18721 tctgaggcgg gcgtcgtagc agccagcacg gcggcagatg ctgggatacc gacagcgatg
    18781 gcggaagaat ttggtcgctt gagtgcgttc gcgaagggca tgttttctcc gtttcagcgt
    18841 ctctgcgtcg aaccactatt gctgcgggca cacgagaatt gcgttgtgaa actatgccgg
    18901 agagattcgg ccctgcaaca gggcgcgaac ggatctgccc gtgcgggcac gaaactattc
    18961 ccttccgggt ccgccgtcag gcatcctcta atcggccgat tcgggaacgg acgagatcgc
    19021 cgggaagccc gctgcggcgc gtcgccgcta cgtgcttcta ccgcgcggac tgagcatttc
    19081 tctttgtcgt tttcgtggtg ggaagcgctg accacgtcat tggttgccgg cgtagttctg
    19141 ggggcctgct gctgttgagg cttctcggga tgctgcattg agcccgggtt tcaccgattc
    19201 gtcgttcgag tggctgaccg ccgttgtccc ttccgctcgg ttcggacgac gaggtctgaa
    19261 cgcgggaccg cgagtgcggc tgccgcggcc cggggcgttg gccggatgat gtagtcgtgg
    19321 atgtgggtca gcgggatgaa ctggtggggg tggccgagtc gcttgagcgg cttgccgccg
    19381 tttcgacgcg tggcgattgg caggtcgagg ggttgctcgc cactcggccg gaggtcgtcg
    19441 ctcacttcga gggtggggct accgagcacg ttgccgaggc tcgggccggt agtgctcggt
    19501 ggatcgccgc tctttcgccc gctctcgtgg agccgctcgc cgcgtggctc cgggcggccg
    19561 ccgggcagga ggagatcgat gcggcggccc tgtcgttcgc tcgggctctt cgtcagcgac
    19621 taccccaatg atcgtcaact cgaggttgac gatccggcgt cgtcaactta tggttgacgc
    19681 atggctgatt cagttgagtt ctccggtcag gttcggctcg acgacctgat ccagtccatc
    19741 aagaaggcgc acggcgacgc cctcgaccag ctcaccgacg ccgtcatcgc ggccgagcac
    19801 ctcggggagg tcgccgatca cctgatcggg cacttcgtcg accaggcccg gcgttcgggc
    19861 gcttcctgga ccgagatcgg gaagagcatg ggcgtctcga agcaggccgc gcagaagcgg
    19921 ttcgtgccga agggcgacgc agcgggtttc gaccccagcc agggattcgg ccggttcacc
    19981 cctcgggccc gcaacgtcgt ggtgctggcg cagaacgcgg cgcgcgacgc gggcaacgtc
    20041 gagatcctgc ccgagcacct ggtgctgggg ctgctcggcg agcccgatgg gatcgccgcg
    20101 caggtgatcg tcgcgcaagg ggtaacgctg gaggccgtcc gggaggccgt gaccgccgcg
    20161 ctgccgccgg cggccgacga ggcgccgcag atcctcccgt tcgacgggtc ggcgcggaag
    20221 gcgctggagc tcaccttccg cgaggccctg cggctcgggc acaactacat cggcaccgag
    20281 cacatcctgc tcgcgctgct ggaaaacgag gacggcaacg gcgttctctc cgggctcggc
    20341 atcgacaagg ccgccgctga ggccagcatc accgccgcgc tcgccgccgt cgttgcccag
    20401 atgaagaaat gatccaccgg cccagccgcc ggtttcgtgt cgccccggct cgggcatccg
    20461 ctgaagatgg cagtcggtag gcggtcgtct ccgggcggaa ggatcgggtc atgggtggcg
    20521 aggaatcggc ggtgggtcgg gctcggttga ccgaggagat ccgcacgttg cgcgcgcggc
    20581 ggcagcagct ggtcgacgag ttgaggcaga ccgacgaccc cggggaccgc ggcgacgccg
    20641 cgcaggagct gcagggcggc gatgagctcg tcgcgatcga cgaccgcatc gccggactgg
    20701 aggggctgct ggccggtggg cagcccgacg tcggaggact ggcgcccggt accgaagtga
    20761 gcctgcggct gcccgacggc acgacgcagg acttccgggt cgtggccatc ccggaggaga
    20821 tcccatcggg cgcggaggat acctcgctga cctccgacag tccgctgggg ctggcgctgg
    20881 ccggcagcca cccgggggag acggtcgatt tcccgacccc ggaaggccga aaccgggtcg
    20941 aggtgatcag tatccggccg ccgagctgac ctgctccgcg actcgccatt gtggacagtc
    21001 gtgggtggac ttccgtcacc gcagcggcgc gcccgatgcg ctgggcagcg ccactgcgga
    21061 gatcggggga gtcgcctgcc gggcaggaga ctccccttct cacgttgcgg cgcctaccgg
    21121 cctggcctcc agggacttcc gcagttccga ctggcgttcg cggtaggccg cgacgttcgc
    21181 gagcttgatc tcctcgtagc cgcggaccat gtccgggagc tccgcgagtt ccagcagcgc
    21241 cgggtggtcc ggcgttgcca gcgcctccgc gatcatcttc cggtactcgt cgatcagttc
    21301 tcgttcgacg cggcggacct tggcgtagcc gaacgggtcc aagcgggtgc cgcggacctt
    21361 ccgcgccgcg cgcagcaggc gcagcacgtg gcggaaccag gggccgaggc tgatcttccg
    21421 gttcatgccg agcgcgcgca gcaccggcgg gtgcagccgg aaggcgaacc gggagcccgc
    21481 gccgaactgg gcttcgacgt cggccagcag cttctcgtcg agcgagagcc gggcgacctc
    21541 gtactcgtcc ttgtaggcca tcagcttgta gaggttgcgg gccaccgctt cggtcaccgc
    21601 atcgactccg cgcccgcgca cctcctcgac gaactccgcg tacgtccgcg cgtagtcctc
    21661 gtcgtggtag tcgacgaggt ccgggatccg gatgtccagc agccgcgcca gttccgagcc
    21721 cgccgcggcc ctgacgagtg cccgcacccg gtgcgccgcg gcgctgggct cgcggggctt
    21781 cgccggcggc ggggtgatct cggcctgcag cgcgtcgggg tccgcgatcg cctggcggcc
    21841 gcggcggaac gcctggatgt tggccgccac cgccgtcccg ttcagctcga tcgcccgctc
    21901 gatgctctcc gccggcagct gcagcgaacc ggcctggtac gccgcgccga gctgcaggat
    21961 gttggcgaac tggtcgtcgt cgaacagctt ctcggcaagg ccgcgcgcat ccaggtagaa
    22021 cgcccgcgcg gtcgcgtcgt cgagggcgga ccggatgccc gactgcaccg ggaacgagac
    22081 ggcggtgtcc acgaccatcc ggccggtcgg gacctcggtg gtggacacca ccgccgtcgt
    22141 ccggccggcg tcggccgcgg cgaggtgcac cgggtcggcc gccaccagca ggtcgcaacc
    22201 caggtagagg tcgcattcgc cggcggccag tttcggtgcc tgcgcaacgg gttccgcggt
    22261 gatcttgagg tcggagacga ccgcgccgcc cttctgcgcg aggccgatct ggtcgagggt
    22321 gcggacctgc cggccgtcga tcaccgccgc cgtcgcgagg atctgcgtga cggtgacgac
    22381 gccggtgccg ccgatgccgg tgatgcggac ggtgaagtcg cccgcgccgt gctccggctc
    22441 gggcagttcg ccggcgctga cctcgctgat cttgcggcgg gccgtgcggc cgctggatac
    22501 cacggtcagg aacgacgggc agtcgccggc caggcaggag tagtcgacgt tgcacgagga
    22561 ctggtggatc tgggtcttgc ggccgaactc ggtggcgacg ggctgcacgg aaaggcagtt
    22621 ggacttggcg ccgcaatccc cgcagccctc gcacacccgc tcgttgatca gcaccttctg
    22681 cgccggcgtg ggctgcttgc cccggcggcg cttgcggcgc ttctcggccg cgcattcctg
    22741 gtcgtggatg agcaccgtga cgccggggac agcggccagt tcttcctgca cgcgcagcag
    22801 atcatcgcgg tgccggatct cgacgccccg gggaagcttg ccgctcaacc gcttgggcgc
    22861 gtcgctggtg acgatgacct tggcgacgcc ttccagcagc agcgtttccg ccagccgcgc
    22921 cagcggaagc gccccgaccg cgtcctggcc gccggtcatc gccaccgccg agttgtgcaa
    22981 cagcttgtag gtgatgttga ccccggcggc gacggtcgcg cggacggcaa ggctgccgga
    23041 gtgcgtgaag gtgccgtcgc cgatgttctg cacgaagtgc tcggtgccga cgaacggcga
    23101 catgccgatc cactgggtgc cctcgccgcc catctgcgtg atgccaacga cgtcgccgac
    23161 ctggtcggcg tccatgaaca gcgccatcgt gtggcagccg atcccggcgc ctaccacggt
    23221 cccttccggc accttcgtcg acgagttgtg cgggcagccc gagcaaaagt acggcgtgcg
    23281 cgccagcagc ggcacggcga tgcgctcgcg gcggcggcgc tgccgccagg cgttgatcgg
    23341 ctccacctcg ccgtgcgcgg tcaggcgccc ggccagaccc ttggcgatgc ggtccgggtc
    23401 gagctcgccg agctcggtga acagggtgcc gccgtccggc cccttcttgc cgtggacggc
    23461 cggggcgtct gggcggccgt agaggatctc cttgatcgcc gtttcgagga acgagcgctt
    23521 ctcctcgacc accacgatct cgctcaaacc ggtcgcgaag tcccggacca gctgcgggtc
    23581 gagcgggtag atcgcgccga gcttgagcag ccggatgccg taccgggcca ggtccgcgtc
    23641 gtcgaggccg agcgcgcgca gcgcctgccg gatgtccaaa taggacttcc cagccgccac
    23701 gatgccgatc cggtctgccg ggcccgagcg caccacgtgg ttgacgccgc tgcgccggag
    23761 gtactcgacc gccagcggca ggcggaggtt gtgcaggctg tgctccaacc ccgcgagctc
    23821 ggcaccgagc aggcgggcgc tggggcggtg cgagtacggc ttcaactcgg ccgggatcgc
    23881 gggtgcgttc caggtcggcg ccacaaccgc tgttccggcc gcatccgcca cgttggcgac
    23941 gaccttcagc gacgtccaca atccgctggc ccgcgacagc tccaccgcgt gcagcccgaa
    24001 atcgagcagg tcctgcgagt ccgccgggaa gaacaccggc atcgccaggt ccgcgagcgc
    24061 cgcctccgag gccgccggaa ccgtcgagga cttcgcgttc gggtcgtcgc cgacgagcgc
    24121 gaccgcgccg ccgcgcgggt tcgcgcccgc gaggttggcg tggcgcaggg cgtcgctggc
    24181 ccggtccagg cccggtgcct tgccgtacca gacgcccacc accccgtccg ggcgctgcgt
    24241 accgaggcct tcggtgagct ggctgcccat caccgacgtc gcggccagct cctcgttcag
    24301 gcccggccgg tggaccacgt cgtgatcggc gagcagcttc gagcggcggg ccagctccag
    24361 gtcgaacccg gccagcggcg agccctcgta gccggagacg aacgccgcgg tgctgtgccc
    24421 ggcgcggcgg tcgtggcgga tccggtcgaa caacagccgc accagggcct gcaccccggt
    24481 cacgtagacg gtgcccgatt cctggaggta gcggtcgtcc agggtgtagg cggccatgtc
    24541 gaactccttt gtcgcggacc cgcgggtcgt gatcgacgcc acttcaaccg aaggtgggtg
    24601 tggcgcacaa caccgcgacc cgaaacgatg gtccacacgc aaacatcggc ggttcagggg
    24661 cttttgcgcg cccgaatttt gcgtaccatc gctgtccatg gccgaagcga cgctcgatgc
    24721 gacagatcac gaaatcctgg ccctgctgcg cgaggacgcg cggcggacgc tgtcggacat
    24781 cgcgacccgg gtgacgctgt ccacggcg
//
