LOCUS       NZ_CP050976            49132 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7905113
            Orig. end                         :: 7954245
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..49132
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="NRPS"
                     /region_number="31"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..49132
                     /SMILES="NC(CCC(=O)O)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..41824
                     /SMILES="NC(CCC(=O)O)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41824
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:21824](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21824
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     misc_feature    complement(388..402)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     gene            405..869
                     /locus_tag="HEP86_RS35045"
                     /old_locus_tag="HEP86_35045"
     CDS             405..869
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS35045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_35045"
                     /product="hypothetical protein"
                     /protein_id="WP_168482634.1"
                     /transl_table=11
                     /translation="MRATRITFILAGLLLPLVGPLSAAEAAPSNPGTPPAQRTSALVDR
                     HQAVMKVADRACVTSGGYGGARFKRLTGPVTKLKVTLWAYDGVSDGQHVRVRLVTKNSK
                     GQRHYWKWHKTSSEKTWHTTARDVYGIFEVGAQVAQFKGDKRLDMCTAWK"
     misc_feature    441..443
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1221..2861
                     /locus_tag="HEP86_RS35050"
                     /old_locus_tag="HEP86_35050"
     CDS             1221..2861
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091924.1"
                     /locus_tag="HEP86_RS35050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35050"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_168482635.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.5e-14, bitscore:
                     50.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRAPRPPSRSGAPQLDAVIVGAGFSGLYQLYRLRALGLRTRVLE
                     ACEDIGGTWYRNRYPGARCDVESTAYSFSFSPELDQEWEWSERYATQPELLRYLHHVAD
                     RFDLRKDITLRTRVTGAVYDEGGHTWQVTTDTGETVTTRFVVLATGCMSAVKEPDIPGA
                     GTFAGRSLHTADWPHEDVDLTGRRVAVIGTGCSGIQAIPILAEQAAELTVFQRTPVYAL
                     PARNRPLSAAETAELKANYPEFRAAQRRSKGGTLFEPPTRSALEVDEEERRATYEEGWD
                     SGVLSGLLRTYTDILVDRDANETVAEFVRSKIRSIVTDPETAETLSPSTFPFGTKRPCL
                     DTGYYATYNKPHVRVVDLTRTPIVEITPRGIRISDREHAVDVIAFATGFDALTGSQVAM
                     DIVGKGGTTLREKWADGPRNHLGLLSAGFPNLFTVIGPLSPSVLSNAVVAIEQHVEWIS
                     DCIAHLRRNGITEIDATPRAEADWRTHVADLAAQTLYPSVDSWYMGANVPGKPRVFLAY
                     TGGLERYRAECAAAAEDGYRAFALSGGAD"
     cand_cluster    3061..49132
                     /SMILES="NC(CCC(=O)O)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3061..49132
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[23060:29132](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      23061..29132
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     gene            3581..4861
                     /locus_tag="HEP86_RS35055"
                     /old_locus_tag="HEP86_35055"
     CDS             3581..4861
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049698.1"
                     /locus_tag="HEP86_RS35055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35055"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_168484196.1"
                     /transl_table=11
                     /translation="MLSSPPPGPTRSGFWRSPLRGPWLTSVFGLILLVGITVLFVTGLL
                     SYASYNPNLAPGNDKTPEKGWLGFYLFSWPTSPYWLYRLTQGIHVTLGVVLIPVLLAKL
                     WSVVPKLFTWPPVRSLSHALERLSLLLLVGGVLFEFVTGVLNIQLHYIFPGSFYTLHFY
                     GAWVFIGAFAVHVAFRIPTMARALRSRRFRSALRTPAARTTPEAADDTGLVTPHPAPPT
                     MSRRGALGLVGAGSLALLVVTAGQSIGGALRKTALLAPHGKEPGKGPNGFQINKTAAEV
                     GIRARDIGPGWRLVVRGPGRERIFTRAQVLALPQHTAALPIACVEGWSTDDLDWSGVRL
                     ADLAALVGLRQSPPGVFVESAQRGGAFSSTHLRDNQVRDPRSLLALRVNGADLSLDHGY
                     PARIIVPANPGVHNTKWVTRLTFGAAQ"
     gene            4858..5376
                     /locus_tag="HEP86_RS35060"
                     /old_locus_tag="HEP86_35060"
     CDS             4858..5376
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049697.1"
                     /locus_tag="HEP86_RS35060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35060"
                     /product="hypothetical protein"
                     /protein_id="WP_248001450.1"
                     /transl_table=11
                     /translation="MKGFRTRYGASPLHLLLVLCSFALAVYAGLRLLKGDTLGVVLWFV
                     GAALLHDLVFLPLYTVTDRVVQRVFRRRRDATDRSHSLTGRINYLRVPAFVALLLLLVW
                     YPLILNRVPGFTSYTGLQAEVFWGRWLLITAALFAASAVCLLVAMWRGHSPRPRAHEAP
                     PKAPGRHQA"
     gene            5414..6127
                     /locus_tag="HEP86_RS35065"
                     /old_locus_tag="HEP86_35065"
     CDS             5414..6127
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538085.1"
                     /locus_tag="HEP86_RS35065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35065"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_248001451.1"
                     /transl_table=11
                     /translation="MSTEEHAPEQPLGPGQRHEDPYAHALQDGRGPLYMRRMDGGVLSS
                     EVDRWCAAPDPADMSVLRRCKGAVLDIGCGPGRLVSALRALGHLVLGIDINHAAVARTA
                     DTGGAALCRSVFERLPGEGLWNTALLMDGNIGIGGDPAALLVRIGSLVSPRGSLLLVEA
                     AAHDVHERLHVQFDDGRGRLGMPFPWARVGVAALRRTAAATGWQPGEHWSVGDRHFLEL
                     KRSAGSRAAHTRRQG"
     gene            complement(6198..7565)
                     /locus_tag="HEP86_RS35070"
                     /old_locus_tag="HEP86_35070"
     CDS             complement(6198..7565)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602326.1"
                     /locus_tag="HEP86_RS35070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35070"
                     /product="hypothetical protein"
                     /protein_id="WP_168484198.1"
                     /transl_table=11
                     /translation="MSARKRECRRDVWAVVAAVVLLALAVVIGRLLNRTVYGAEGVLRL
                     GWPPLSAWWLPHIGPGTPAALAVAALVVVYGPPTARRLSWRVLVPAVWGAAMAWTWSLA
                     LVDGWGRGIAERLTTSLEYLQSVKDVHDVPAFLRDFTNHILVGSPHIWPAHVAGHPPGA
                     LLTFVGLDRIGLSGGAWAAAWCITVGSSFAAAVAVAVRALCGEQLARQAAPFLVLAPAA
                     VWIGVSADGYFAGVSAWAVALLALAAGRTTRMPGLAALGAGLLLGLAWYLSYGLTVLVV
                     LGAAVLLLARSARPLPLVLLGVLPWVAAFTAAGFWWLDGYTTLVERYYQGAAKVRPYGY
                     FIWANLAAQVLTVGLATVAGLCRAAGPLRPAVRGMRRRSPAGRGALSVLVAAALCMMLL
                     ADLSGMSKAETERIWLTFAVWLLPACALLPRRAHARWLATQAVLALLVNHLLLTGW"
     gene            complement(7919..8074)
                     /locus_tag="HEP86_RS35075"
                     /old_locus_tag="HEP86_35075"
     CDS             complement(7919..8074)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS35075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_35075"
                     /product="hypothetical protein"
                     /protein_id="WP_168482636.1"
                     /transl_table=11
                     /translation="MTRLADNDQETRGSWLVEAWSAFAGHCAAHRYLLQTPVTGAPPRD
                     RPATAP"
     gene            8279..9331
                     /locus_tag="HEP86_RS35080"
                     /old_locus_tag="HEP86_35080"
     CDS             8279..9331
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (58-256). E-value:
                     5.4e-09. Score: 27.5. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35080_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998923.1"
                     /locus_tag="HEP86_RS35080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35080"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_168482637.1"
                     /transl_table=11
                     /translation="MLILVTGGAGFIGSHVVTALTGAGHGVRVLDALLPAAHRTSPPIP
                     DGVDRRHADVRDAAAVAEALQGVDAVCHQAAMVGLGKDFADAPAYVGCNDLGTAVLLAG
                     MAEAGVRRLVLASSMVVYGEGRYECPGHGVVRPEPRKVADLEVGRFEPSCPRCGEPLAP
                     GLVAEDAPLDPRNVYAATKLAQEHLAFAWARAVGGRVAALRYHNVYGPGMPRDTPYAGV
                     AALLRSALERGEAPRVFEDGGQRRDFVHVRDVSRANLAALDGLPGLLEGSTRAYNVGSG
                     EPHTVGEMAAVLAEAHGGRMPVVTGEYRLGDVRHITASSRRLRDELGWKPEVAFAEGMA
                     EFAAASLRAG"
     misc_feature    complement(8282..8295)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     aSDomain        8453..9046
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35080_NAD_binding_4.1"
                     /evalue="5.40E-09"
                     /label="HEP86_RS35080_NAD_binding_4.1"
                     /locus_tag="HEP86_RS35080"
                     /protein_end="256"
                     /protein_start="58"
                     /score="27.5"
                     /tool="antismash"
                     /translation="AAVAEALQGVDAVCHQAAMVGLGKDFADAPAYVGCNDLGTAVLLA
                     GMAEAGVRRLVLASSMVVYGEGRYECPGHGVVRPEPRKVADLEVGRFEPSCPRCGEPLA
                     PGLVAEDAPLDPRNVYAATKLAQEHLAFAWARAVGGRVAALRYHNVYGPGMPRDTPYAG
                     VAALLRSALERGEAPRVFEDGGQRRDFVHVRDVSR"
     gene            complement(<9361..>9531)
                     /locus_tag="HEP86_RS41170"
                     /pseudo=""
     CDS             complement(<9361..9531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018841399.1"
                     /locus_tag="HEP86_RS41170"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHSAELSLTVREFDLLAYLLRNPGRATSR"
     misc_feature    complement(9732..9747)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.59"
                     /tool="antismash"
     misc_feature    complement(9788..9803)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            9834..10562
                     /locus_tag="HEP86_RS35085"
                     /old_locus_tag="HEP86_35085"
     CDS             9834..10562
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055551.1"
                     /locus_tag="HEP86_RS35085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35085"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_168482638.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.9e-18,
                     bitscore: 65.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIETSPSSAAPVDVVLPCLDEAEALPWVLGRIPSGWRAIVVDNGS
                     VDGSRDIARALGAHVVHEPRRGFGAACHAGLTAATADIVCFCDCDASLDPALLPAVGGP
                     VLDGSADLVLGRRRPVTRRAWPLHARLANLELARLIRRRTGLRLHDLGPMRAARRQSLL
                     ALDLTDRRSGYPLQMVVRAADAGWRVAETDVPYRPRTGRSKVTGTWRGTWQAVRDMRAV
                     LAERPVTDPVSAATTPGTGR"
     gene            10559..11203
                     /locus_tag="HEP86_RS35090"
                     /old_locus_tag="HEP86_35090"
     CDS             10559..11203
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557634.1"
                     /locus_tag="HEP86_RS35090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35090"
                     /product="DUF2064 domain-containing protein"
                     /protein_id="WP_168482639.1"
                     /transl_table=11
                     /translation="MSARLPATLLVIAKEPVPGRVKTRLTPPYAPQEAAALAEAALADT
                     LHTVLKVPVRRRVLVLDGVPGPWLPPGFDIVPQGAGGLDERIAAAFGHCDRGPAVLIGM
                     DTPQLTADLLAGVGRDSADAWFGPAADGGFWALGLADPAHAAALVRGVPMSTDRTGAIQ
                     RRRLAEAGLSVSELPVLRDVDTAADAAAVAACCPPGSRFTTTLNSLAEAGR"
     gene            <11306..>11523
                     /locus_tag="HEP86_RS41175"
                     /old_locus_tag="HEP86_35095"
                     /pseudo=""
     CDS             11306..>11523
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099808.1"
                     /locus_tag="HEP86_RS41175"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="HEP86_35095"
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGELLPLDVERCCAAPDAADTSVLHRCTGPVLGIGCGPERLMAAL
                     AAQGVRALGVDVSPA"
     gene            <11524..11631
                     /locus_tag="HEP86_RS42000"
                     /old_locus_tag="HEP86_35100"
                     /pseudo=""
     CDS             <11524..11631
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151528.1"
                     /locus_tag="HEP86_RS42000"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35100"
                     /product="TetR/AcrR family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="IVAAGLALNAAMQLRHDRSAADRAPRAIERALDQS"
     gene            complement(11838..12563)
                     /locus_tag="HEP86_RS35105"
                     /old_locus_tag="HEP86_35105"
     CDS             complement(11838..12563)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124296.1"
                     /locus_tag="HEP86_RS35105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35105"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_168482640.1"
                     /transl_table=11
                     /translation="MTTITTRTVEYPADNLTMIGYLALPAGAGRRPAVLIGPEGIGLSD
                     VERRRAEALAELGYVALAFDLHGGRYLEDPEEMLARCMPLLADPDRMRDIGHAALDVLR
                     AEPRADPDRIAAVGYGTGGAVALELGRDGVDLRAIATVNALTTGRPGEAARIRCPVWVG
                     VGSEDPIMPPAQRDAFTAEMQAAGVDWRLVVYGGALHAFHHPPVDHTVRPGVGYHPRHA
                     ERAWHDIVALLAECLPVTD"
     gene            12828..13253
                     /locus_tag="HEP86_RS41180"
     CDS             12828..13253
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS41180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_248001452.1"
                     /transl_table=11
                     /translation="MANLVCKRVSTDQQSTARHPRTGELLSTVKFMVQTLAAAGELQRD
                     LQRELTYDGLRAAEAKGNKGGRRPAVAAAKTDAIRTVYLEGRSVAALAREHGVSLPDGD
                     RTARTHPRPAVRWAAAYGSVPGGPGGDGADRKRGWAE"
     gene            complement(13263..14255)
                     /locus_tag="HEP86_RS35115"
                     /old_locus_tag="HEP86_35115"
     CDS             complement(13263..14255)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019357530.1"
                     /locus_tag="HEP86_RS35115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35115"
                     /product="phospholipase"
                     /protein_id="WP_168482641.1"
                     /transl_table=11
                     /translation="MASPRRLRAVLLPLALVVSAATLGTGAAMAVPEDKPSKAAPGATD
                     QRPTWAIAHRVLTTGGVTRALENGANALEMDATAWRKGWWADHDGTLTSYGDPMSAMFD
                     QVAKEHEQGRQASFVWLDMKNPDWCDSNDPKWRHCSVAGLRDMARKKLESKGIRVLYGF
                     YGKEGGSGWKTALADLNSKEAVSFSGDYAQVRDGFAEHGPNVPGNQRVMDNGLFNMALK
                     FGSIRKELEAGRKARDTGELGLTVGWTVGKGDGDRAATLLDASGGSAAVDSLIYGNRMS
                     CYPDGVSGPKGCGTDDSAVRESLSYLTDYVKAHPDTRRMATPRDIPFGS"
     misc_feature    14377..14394
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.0"
                     /tool="antismash"
     gene            14702..15994
                     /locus_tag="HEP86_RS35120"
                     /old_locus_tag="HEP86_35120"
     CDS             14702..15994
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (2-294). E-value:
                     1.8e-80. Score: 262.4. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35120_Condensation_Starter.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537330.1"
                     /locus_tag="HEP86_RS35120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35120"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_248001453.1"
                     /sec_met_domain="Condensation (E-value: 2.1e-31, bitscore:
                     108.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSPLTAGQLEIWISQVLEPGSPVYNVGDYYEITGAVDAKLLEAA
                     ARTAVDEAGSLGARFLVATDGTPYQELGPAEWSFEVLDMSERPDPDAEAVAWMRAEMAR
                     PVDLTRGSLLAGALIKVSRDRHFWYRRFHHIITDGHGTAAVARRTAALYHSMHTGSPCE
                     PNPFAPVTAAVEHDRAYRAGRMYAADREFWEKVALDWPATGRLRADAPPAPATLQYSHH
                     LPRQVVDAVRAQSERLEVSTARFLITAAALYLWQVTGADEVTFGCSATSRPTRLLRNVV
                     APMANLLPFRVLVEPERSVTDTFRRTDRQIGQALRHHRYRYEEFRRTLAAGPEQHGVGP
                     VVNIVNFDRDLRFGPATGVVRTLVTGPIPDLGLYFDVHSEHAGTSVCVEANPANYTAEE
                     AARHAEGLGGLVRELAGVDPGLPVRALGRPR"
     aSDomain        14708..15583
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35120_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.80E-80"
                     /label="HEP86_RS35120_Condensation_Starter.1"
                     /locus_tag="HEP86_RS35120"
                     /protein_end="294"
                     /protein_start="2"
                     /score="262.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIITDG"
                     /tool="antismash"
                     /translation="SPLTAGQLEIWISQVLEPGSPVYNVGDYYEITGAVDAKLLEAAAR
                     TAVDEAGSLGARFLVATDGTPYQELGPAEWSFEVLDMSERPDPDAEAVAWMRAEMARPV
                     DLTRGSLLAGALIKVSRDRHFWYRRFHHIITDGHGTAAVARRTAALYHSMHTGSPCEPN
                     PFAPVTAAVEHDRAYRAGRMYAADREFWEKVALDWPATGRLRADAPPAPATLQYSHHLP
                     RQVVDAVRAQSERLEVSTARFLITAAALYLWQVTGADEVTFGCSATSRPTRLLRNVVAP
                     MANLLPFRVLV"
     CDS_motif       14768..14881
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35120_0001"
                     /evalue="2.60E-13"
                     /label="C2_starter_024-063"
                     /locus_tag="HEP86_RS35120"
                     /protein_end="60"
                     /protein_start="22"
                     /score="42.5"
                     /tool="antismash"
                     /translation="PVYNVGDYYEITGAVDAKLLEAAARTAVDEAGSLGARF"
     CDS_motif       15095..15160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35120_0002"
                     /evalue="1.90E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="HEP86_RS35120"
                     /protein_end="153"
                     /protein_start="131"
                     /score="27.1"
                     /tool="antismash"
                     /translation="FHHIITDGHGTAAVARRTAALY"
     CDS_motif       15509..15574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35120_0003"
                     /evalue="1.10E-03"
                     /label="C5_starter_265-294"
                     /locus_tag="HEP86_RS35120"
                     /protein_end="291"
                     /protein_start="269"
                     /score="11.6"
                     /tool="antismash"
                     /translation="TSRPTRLLRNVVAPMANLLPFR"
     CDS_motif       15626..15733
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35120_0004"
                     /evalue="2.10E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="HEP86_RS35120"
                     /protein_end="344"
                     /protein_start="308"
                     /score="29.9"
                     /tool="antismash"
                     /translation="RQIGQALRHHRYRYEEFRRTLAAGPEQHGVGPVVNI"
     gene            complement(16014..17033)
                     /locus_tag="HEP86_RS35125"
                     /old_locus_tag="HEP86_35125"
     CDS             complement(16014..17033)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537331.1"
                     /locus_tag="HEP86_RS35125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35125"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_168482642.1"
                     /transl_table=11
                     /translation="MMNTSEPPGRIELSEEASLVFGYATQRAVWGIEELTTVVGLDSAD
                     VERAVKELVEMRLLCRAEGEAGRLTVVPPRTAADRLLRPLERHVRERYEEIERLRETFA
                     SLLPAYESGRARRSDAEPIELLTDLRTVQETIDELTIGARQEVLTAQPGGARSARALQE
                     ADERDRQMLTRGVRMRTLYQHPARYDQPTVDHVRRVMHLGAQVRTRTDGLCRLLVFDHR
                     VALLGLRDDPEAALLVREPHVVHYIRVFFDCLWRDASLFPVSFDSAAAVRISGEIQESI
                     VAMLSEGLEDKSIARRLGMSVRSCQRHASEIMKAVGAKSRFQAGYVLGRLHAAARDRE"
     misc_feature    17082..17100
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.07"
                     /tool="antismash"
     misc_feature    complement(17089..17106)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.63"
                     /tool="antismash"
     gene            17146..18435
                     /locus_tag="HEP86_RS35130"
                     /old_locus_tag="HEP86_35130"
     CDS             17146..18435
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087828.1"
                     /locus_tag="HEP86_RS35130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35130"
                     /product="MFS transporter"
                     /protein_id="WP_248001454.1"
                     /transl_table=11
                     /translation="MPVKTGHRAARSAGGGLLRRHRDFRQLWYGETAGKFGVSVTGVLL
                     PLAAVSVLHAGTFAVSLLNVATWLPWLVIGLPAGVWVDRLRRRTVMLVCDAVSCALFLS
                     VPVAAWCGVLGIGQLLLVALLVGSAAVFFQTAYTAYLPTLLSPPDQAEGNAKLHGSAAA
                     AQIAGVGSGGLIAQAAGAVDGMLTNAATFLISFLCIGRIRHREPPAAGSRSGQRAPLLG
                     DLREGVRLVARDPYLRSLTLFGGASNLALGGCQALLVVFLARDIGLSSGAVGALVGLGG
                     AGGVLGALLVRRGAARLGTARALLLFELGVPALAPLMALTRDGAGLAFFVVGYGAAALG
                     VVAGNIIKAGFIQGYCPSGVLGRVTACSAFVNYGTLPLGALLAGGLGTLLGVRPTMWLL
                     TAAMPLAALILLWSPIRSRRDLPAREADLS"
     misc_feature    17197..17199
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    17815..17817
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18590..18823
                     /locus_tag="HEP86_RS35135"
                     /old_locus_tag="HEP86_35135"
     CDS             18590..18823
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS35135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_35135"
                     /product="hypothetical protein"
                     /protein_id="WP_168482643.1"
                     /transl_table=11
                     /translation="MLLVHAFPDGNVNRVGTAGKSDWHPRPEQFRSAFRQNVLRAVRGT
                     DRAESGADSMYRADSTYRADSCRGTVRTFPMT"
     gene            18970..20004
                     /locus_tag="HEP86_RS35140"
                     /old_locus_tag="HEP86_35140"
     CDS             18970..20004
                     /EC_number="1.14.11.-"
                     /GO_function="GO:0051213 - dioxygenase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: TauD (40-319). E-value: 2e-48. Score:
                     157.4. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35140_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578686.1"
                     /locus_tag="HEP86_RS35140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35140"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_168482644.1"
                     /sec_met_domain="TauD (E-value: 2.6e-46, bitscore: 157.4,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSRSATAEPPAWTLEPGKPAMAHVPRFADAAEAAEWLGSVHAE
                     LRTALHRHGAVYLRGLPVRDVEDFAKVRDVLVPRRTPYREKATPRSSYGNDVYSSTDLP
                     PNQPIRMHNENSYTLTFPGLLLFSCLTAPEEGGATPVADCREVLRRIPSALVERMRSAG
                     WLLTRNYSEHISLDWRTAFAADTREQTEKYCADNLISCEWDASGALRTRQLRPGIIRHP
                     QTGEEVWFNHMAFWNSWSLDEEIREALLDEFGPDGLPFETGLGDGAPLTRDELDAINAA
                     YEGATVRETWQPGDVLLVDNVLATHGRDPFRGDRRIVVAMGEPVALADCRPTVPPAPGE
                     ERAA"
     aSDomain        19090..19926
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35140_TauD.1"
                     /evalue="2.00E-48"
                     /label="HEP86_RS35140_TauD.1"
                     /locus_tag="HEP86_RS35140"
                     /protein_end="319"
                     /protein_start="40"
                     /score="157.4"
                     /tool="antismash"
                     /translation="SVHAELRTALHRHGAVYLRGLPVRDVEDFAKVRDVLVPRRTPYRE
                     KATPRSSYGNDVYSSTDLPPNQPIRMHNENSYTLTFPGLLLFSCLTAPEEGGATPVADC
                     REVLRRIPSALVERMRSAGWLLTRNYSEHISLDWRTAFAADTREQTEKYCADNLISCEW
                     DASGALRTRQLRPGIIRHPQTGEEVWFNHMAFWNSWSLDEEIREALLDEFGPDGLPFET
                     GLGDGAPLTRDELDAINAAYEGATVRETWQPGDVLLVDNVLATHGRDPFRGDRRIVV"
     gene            20001..21824
                     /locus_tag="HEP86_RS35145"
                     /old_locus_tag="HEP86_35145"
     CDS             20001..21824
                     /NRPS_PKS="Domain: AMP-binding (22-419). E-value: 2.9e-96.
                     Score: 314.5. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35145_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (534-602). E-value: 2.3e-23. Score:
                     74.2. Matches aSDomain: nrpspksdomains_HEP86_RS35145_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523876.1"
                     /locus_tag="HEP86_RS35145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35145"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_168482645.1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-102, bitscore:
                     341.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-16, bitscore:
                     57.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELLEDRRHAAPDHAVDLLTRFQQAVAATPDRIAVSHHGALTFA
                     ELDRHTARLAGVLAGHGAAPGRRIGISLPRGTDLVVALLAVWRTGAAYVPLDPAYPQER
                     LHAMVRDAGIDVVLTGGSDGPVWPEGVRTLPVAPPPEAPAPEHAPAPPVPVSARTPAYV
                     IYTSGSTGVPKGVETTRGAVAALVTGLEEAGFYDHGHRVVAWNASVSFDASVQQWARVC
                     RGDTVVVLGEAERTDPALLGAVLDEHGVHDLDLTPSHWPLLRDDLLVRAAEGRRLRLFM
                     GGEAVPEGTWRELAAAHDARRLEAVNLYGPTECTVDATAAWIEDFAPHIGRPLPGVRCH
                     VLDAALRPVPFGEEGELYLAGRQLAVGYVNRPALTATRFVADPFAADGTRMYRTGDLVR
                     RRPDNSLEYRGRSDRQVKLRGHRVELGDIEAALTTHPGVAAAVVTLHSDTAVGEQLVAY
                     YVAATGAAGDTPATGTPTPDTLRAHLAAALPQFMRPTAYLALDAMPLTVNGKVDLTALP
                     APEPATADPDSAPESEAETLIATVWSEVLGREHIRADDDFFAMGGHSLIALRVVARLKK
                     QLGVVMSAREVYQHPRLRDLARHVESLRADR"
     aSDomain        20067..21257
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35145_AMP-binding.1"
                     /evalue="2.90E-96"
                     /label="HEP86_RS35145_AMP-binding.1"
                     /locus_tag="HEP86_RS35145"
                     /protein_end="419"
                     /protein_start="22"
                     /score="314.5"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FQQAVAATPDRIAVSHHGALTFAELDRHTARLAGVLAGHGAAPGR
                     RIGISLPRGTDLVVALLAVWRTGAAYVPLDPAYPQERLHAMVRDAGIDVVLTGGSDGPV
                     WPEGVRTLPVAPPPEAPAPEHAPAPPVPVSARTPAYVIYTSGSTGVPKGVETTRGAVAA
                     LVTGLEEAGFYDHGHRVVAWNASVSFDASVQQWARVCRGDTVVVLGEAERTDPALLGAV
                     LDEHGVHDLDLTPSHWPLLRDDLLVRAAEGRRLRLFMGGEAVPEGTWRELAAAHDARRL
                     EAVNLYGPTECTVDATAAWIEDFAPHIGRPLPGVRCHVLDAALRPVPFGEEGELYLAGR
                     QLAVGYVNRPALTATRFVADPFAADGTRMYRTGDLVRRRPDNSLEYRGRSDRQVKLR"
     aSModule        20067..21806
                     /complete
                     /domains="nrpspksdomains_HEP86_RS35145_AMP-binding.1"
                     /domains="nrpspksdomains_HEP86_RS35145_PCP.1"
                     /locus_tags="HEP86_RS35145"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20250..20291
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35145_0001"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="HEP86_RS35145"
                     /protein_end="97"
                     /protein_start="83"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LAVWRTGAAYVPLD"
     CDS_motif       20481..20531
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35145_0002"
                     /evalue="9.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="HEP86_RS35145"
                     /protein_end="177"
                     /protein_start="160"
                     /score="27.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGVPKGVE"
     CDS_motif       21048..21137
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35145_0003"
                     /evalue="2.00E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="HEP86_RS35145"
                     /protein_end="379"
                     /protein_start="349"
                     /score="42.4"
                     /tool="antismash"
                     /translation="PFGEEGELYLAGRQLAVGYVNRPALTATRF"
     CDS_motif       21222..21287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35145_0004"
                     /evalue="8.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="HEP86_RS35145"
                     /protein_end="429"
                     /protein_start="407"
                     /score="33.9"
                     /tool="antismash"
                     /translation="YRGRSDRQVKLRGHRVELGDIE"
     aSDomain        21603..21806
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35145_PCP.1"
                     /evalue="2.30E-23"
                     /label="HEP86_RS35145_PCP.1"
                     /locus_tag="HEP86_RS35145"
                     /protein_end="602"
                     /protein_start="534"
                     /score="74.2"
                     /tool="antismash"
                     /translation="ETLIATVWSEVLGREHIRADDDFFAMGGHSLIALRVVARLKKQLG
                     VVMSAREVYQHPRLRDLARHVES"
     gene            21987..22763
                     /locus_tag="HEP86_RS35150"
                     /old_locus_tag="HEP86_35150"
     CDS             21987..22763
                     /NRPS_PKS="Domain: Thioesterase (20-237). E-value: 2.5e-40.
                     Score: 131.3. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35150_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537335.1"
                     /locus_tag="HEP86_RS35150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35150"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_168482646.1"
                     /sec_met_domain="Thioesterase (E-value: 8.2e-39, bitscore:
                     133.0, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.7e-09, bitscore:
                     36.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGPQDTTVIPIKPPDRHTVRTLLCLGFCGGGTGPYHSWSDSLPA
                     EVALSAICYPGREGRFLEPYAADWEELAADATAAVLSAADGPYVLFGHSMGGWMAFDVA
                     ARIEDAAGPAPEALVVSSCNAPDRGLTPRDMFPARQDTDAELLDWMRTNGLMPEHVLAD
                     PGLQEMAVELMRADIRVRDTFRCRPGTTVGVPVQMLSATDDDVIEPDAGNQWRRVARGA
                     YRHDVLPGGHFYTPEIWRQLPAHIAPLTTPASHAAV"
     aSDomain        22047..22697
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35150_Thioesterase.1"
                     /evalue="2.50E-40"
                     /label="HEP86_RS35150_Thioesterase.1"
                     /locus_tag="HEP86_RS35150"
                     /protein_end="237"
                     /protein_start="20"
                     /score="131.3"
                     /tool="antismash"
                     /translation="RTLLCLGFCGGGTGPYHSWSDSLPAEVALSAICYPGREGRFLEPY
                     AADWEELAADATAAVLSAADGPYVLFGHSMGGWMAFDVAARIEDAAGPAPEALVVSSCN
                     APDRGLTPRDMFPARQDTDAELLDWMRTNGLMPEHVLADPGLQEMAVELMRADIRVRDT
                     FRCRPGTTVGVPVQMLSATDDDVIEPDAGNQWRRVARGAYRHDVLPGGHFYTPE"
     CDS_motif       22239..22304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35150_0001"
                     /evalue="2.50E-11"
                     /label="NRPS-te1"
                     /locus_tag="HEP86_RS35150"
                     /protein_end="106"
                     /protein_start="84"
                     /score="35.9"
                     /tool="antismash"
                     /translation="DGPYVLFGHSMGGWMAFDVAAR"
     gene            22825..23031
                     /locus_tag="HEP86_RS41185"
     CDS             22825..23031
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009: mbtH-like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537336.1"
                     /locus_tag="HEP86_RS41185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MbtH family protein"
                     /protein_id="WP_248001455.1"
                     /transl_table=11
                     /translation="MTHTHPFEDVDATYLVLVNQHNQHSLWPSHLAPPQGWTVTRGADG
                     YQACLDHIEEHWRDLSPQPATGN"
     gene            23061..29132
                     /locus_tag="HEP86_RS35160"
                     /old_locus_tag="HEP86_35160"
     CDS             23061..29132
                     /NRPS_PKS="Domain: PCP (36-105). E-value: 2.3e-27. Score:
                     87.0. Matches aSDomain: nrpspksdomains_HEP86_RS35160_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (119-412). E-value:
                     2.7e-111. Score: 363.3. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35160_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (609-678). E-value: 2.3e-27. Score:
                     87.0. Matches aSDomain: nrpspksdomains_HEP86_RS35160_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (692-985). E-value:
                     1.3e-111. Score: 364.3. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35160_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1156-1569). E-value:
                     2.6e-106. Score: 347.6. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35160_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1676-1745). E-value: 3.1e-28.
                     Score: 89.8. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35160_PCP.3"
                     /NRPS_PKS="Domain: Thioesterase (1776-2010). E-value:
                     2.4e-40. Score: 131.3. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35160_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="HEP86_RS35160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35160"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_168482648.1"
                     /sec_met_domain="PP-binding (E-value: 1.7e-13, bitscore:
                     49.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.2e-70, bitscore:
                     234.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-110, bitscore:
                     366.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.3e-05, bitscore: 21.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 4.1e-33, bitscore:
                     114.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAQSPAVGEQADATAPSGDGPGRAGRGRGPRSVREEVLCRLFA
                     QVLGVPTVGVADNFFALGGHSLRAAQLLSRIRSVLGVELGVRELFGSPTVAGLADLLAE
                     GAVARPAVTARARPAVVPLSFAQQRLWFLDRLEQSPTYNAPFAFRVRGPVDADALQSAV
                     NDVVGRHEALRTVFPVRDDEPFQDILAPEHATVKVTVVPCAAEELNSLFHDVAFAPFDL
                     AVELPLRVSLFTTAPDEHVLLLTLHHIASDGWSEAPLLRDLSTAYRARLTDSVPVWEAL
                     PVQYADYTLWQRELLAEVGGQQSDFWVEALEGLPQELALPTDRPRPSRPTHSGGLVHFR
                     LPADLHGRLESLAREQGATLFMVLQAGLAALLTRLGAGTDIPLGTATAGRTDQALDDIV
                     GFFVNTLVLRTDTAGDPSFGELLARTREGDLAAFAHQDLPFEQLVERLNPDRSTSRHPL
                     FQTMLVLQNNAEGTLDLPGTTLTPQPLDTAPSKFDLGWSFTEERDADERPLGMSGILQY
                     ATDLFDRTTADTLTGLLVRALDAAADAPDTAIGSLEIFASRTAERAFLDRTDEHRLPAR
                     RASGPGGAADAGPTSGDGPDRGGRGERGPRSAREEVLCQLFAQVLGVPTVGVADNFFAL
                     GGHSLLATRLLSRIRSVLGVELGVREFFGSPTAAGLADLLAEGAVARPAVTARARPAVV
                     PLSFAQQRLWFLDRLEQSPTYNAPFAFRVRGPVDADALQSAVNDVVGRHEALRTVFPAH
                     EGEPQQQLLAPDEAAVEVTVVPCPADEISARFHAAAFTPFDLAEELPLRVTLFTVGAED
                     HLLLLTLHHIASDGWSLVPLLRDLSMAYRARLTGSVPVWEALAVQYADYALWQRELLAE
                     VGGQQSDFWVEALEGLPQELALPTDRPRPPQPTHSGGLVHFRLPADLHGRLELLAREQG
                     ATLFMVLQAGLAALLTRLGAGTDIPLGTATAGRTDQALDDIVGFFVNTLVLRTDTSGDP
                     SFGELLARTREGDLAAFAHQDLPFEQLVERLNPDRSTSRHPLFQTMLVLQNNAEGTLDL
                     PGTTLTPQPLDTAPTKFDLDFTFTERHGADGSPDGVDGLLHYSADLFERATAEALPQRL
                     LSLLTTAGAAPETPIGAMELLSPQERVRILSGWNDTALPLPDDRLVHEIFEEHVRNSPD
                     ATAVVDADGTLTFRELNARANRLAWLLISQGIRPEQRVATLLPRAGEHIVALLAALKAG
                     CCYVPMDPEDPEDRIALMLADAAPSFLLTDRENLARLRPGADPSIQVLVLDDPAVRQSL
                     SRYAPVDPHSADRPVPLRPDHLAYVIYTSGSTGRPKGVAVEHRNLSNLFHAHFAVFAPQ
                     VAAAGDHRFRALVTGPLTFDSSWEPVLWLLGGHELHLVHDEVRRDPEAMAEYIGAAGID
                     YMEISPTYCRQLMTAGMLSAGQPSQPRIVELGGEAVDQALWSELRAISGTEGFNSYGPT
                     ECTVYVSYGAAAEHERPLIGRPISNNRMYVLDAGLRPLPAGVVGELYLAGAGTARGYLG
                     RPGLTAQRFVACPFGEPGERMYRTGDLARWSADGVLEYMGRTDEQVKVRGFRIEPGEVE
                     SVLAGHDAVRQVTVIVREDRPGERKLVAYVVPTEQGRADARELRRLATASLPRHMVPSS
                     FVFLDALPLTSRGKLDRRMLPAPGDGTVERRRGPRTVREELLCGLFAEVLGVPEVGIDD
                     DFFALGGHSMLATRLIARTRSVLGAELGIRTLFDAPTVAGLADRLSQDTPDDSLAVLLP
                     LRSVRRAATPSRTRGATPPEPLFCVHPAAGTSWVYSGLLRHLALDQPVYGLQAHGLTEP
                     DAAPESMTEMVEAYLAQIRSVQPDGPYSLLGWSFGGVVAHEMAVRLQEAGQKVNSLVLM
                     DSYPSRVTADGHDTGRTEKSGSGTDRGDAPDAEELRQALFDSLGHQADATDGPLALLGE
                     QGLAAMVRVFARNSRLQSGFVPRSFRGDVLFFEATEGWVPGMQRPQAWRPHVTGRLAIT
                     PVRGAHGELTRPEQLAQIGPVLADWCAEYRK"
     aSDomain        23169..23375
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_PCP.1"
                     /evalue="2.30E-27"
                     /label="HEP86_RS35160_PCP.1"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="105"
                     /protein_start="36"
                     /score="87.0"
                     /tool="antismash"
                     /translation="EEVLCRLFAQVLGVPTVGVADNFFALGGHSLRAAQLLSRIRSVLG
                     VELGVRELFGSPTVAGLADLLAEG"
     aSDomain        23418..24296
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.70E-111"
                     /label="HEP86_RS35160_Condensation_LCL.1"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="412"
                     /protein_start="119"
                     /score="363.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIASDG"
                     /tool="antismash"
                     /translation="VVPLSFAQQRLWFLDRLEQSPTYNAPFAFRVRGPVDADALQSAVN
                     DVVGRHEALRTVFPVRDDEPFQDILAPEHATVKVTVVPCAAEELNSLFHDVAFAPFDLA
                     VELPLRVSLFTTAPDEHVLLLTLHHIASDGWSEAPLLRDLSTAYRARLTDSVPVWEALP
                     VQYADYTLWQRELLAEVGGQQSDFWVEALEGLPQELALPTDRPRPSRPTHSGGLVHFRL
                     PADLHGRLESLAREQGATLFMVLQAGLAALLTRLGAGTDIPLGTATAGRTDQALDDIVG
                     FFVNTLVLRTDT"
     aSModule        23418..25094
                     /domains="nrpspksdomains_HEP86_RS35160_Condensation_LCL.1"
                     /domains="nrpspksdomains_HEP86_RS35160_PCP.2"
                     /incomplete
                     /locus_tags="HEP86_RS35160"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23430..23462
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0001"
                     /evalue="3.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="134"
                     /protein_start="123"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SFAQQRLWFLD"
     CDS_motif       23478..23594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0002"
                     /evalue="8.20E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="178"
                     /protein_start="139"
                     /score="56.8"
                     /tool="antismash"
                     /translation="PTYNAPFAFRVRGPVDADALQSAVNDVVGRHEALRTVFP"
     misc_feature    23742..23744
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       23796..23861
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0003"
                     /evalue="1.50E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="267"
                     /protein_start="245"
                     /score="30.3"
                     /tool="antismash"
                     /translation="LHHIASDGWSEAPLLRDLSTAY"
     CDS_motif       23910..23948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0004"
                     /evalue="2.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="296"
                     /protein_start="283"
                     /score="16.8"
                     /tool="antismash"
                     /translation="QYADYTLWQRELL"
     CDS_motif       24198..24287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0005"
                     /evalue="1.20E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="409"
                     /protein_start="379"
                     /score="40.2"
                     /tool="antismash"
                     /translation="DIPLGTATAGRTDQALDDIVGFFVNTLVLR"
     CDS_motif       24339..24455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0006"
                     /evalue="2.00E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="465"
                     /protein_start="426"
                     /score="71.6"
                     /tool="antismash"
                     /translation="EGDLAAFAHQDLPFEQLVERLNPDRSTSRHPLFQTMLVL"
     aSDomain        24888..25094
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_PCP.2"
                     /evalue="2.30E-27"
                     /label="HEP86_RS35160_PCP.2"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="678"
                     /protein_start="609"
                     /score="87.0"
                     /tool="antismash"
                     /translation="EEVLCQLFAQVLGVPTVGVADNFFALGGHSLLATRLLSRIRSVLG
                     VELGVREFFGSPTAAGLADLLAEG"
     aSDomain        25137..26015
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.30E-111"
                     /label="HEP86_RS35160_Condensation_LCL.2"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="985"
                     /protein_start="692"
                     /score="364.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIASDG"
                     /tool="antismash"
                     /translation="VVPLSFAQQRLWFLDRLEQSPTYNAPFAFRVRGPVDADALQSAVN
                     DVVGRHEALRTVFPAHEGEPQQQLLAPDEAAVEVTVVPCPADEISARFHAAAFTPFDLA
                     EELPLRVTLFTVGAEDHLLLLTLHHIASDGWSLVPLLRDLSMAYRARLTGSVPVWEALA
                     VQYADYALWQRELLAEVGGQQSDFWVEALEGLPQELALPTDRPRPPQPTHSGGLVHFRL
                     PADLHGRLELLAREQGATLFMVLQAGLAALLTRLGAGTDIPLGTATAGRTDQALDDIVG
                     FFVNTLVLRTDT"
     aSModule        25137..29090
                     /complete
                     /domains="nrpspksdomains_HEP86_RS35160_Condensation_LCL.2"
                     /domains="nrpspksdomains_HEP86_RS35160_AMP-binding.1"
                     /domains="nrpspksdomains_HEP86_RS35160_PCP.3"
                     /domains="nrpspksdomains_HEP86_RS35160_Thioesterase.1"
                     /final_module
                     /locus_tags="HEP86_RS35160"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25149..25181
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0007"
                     /evalue="3.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="707"
                     /protein_start="696"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SFAQQRLWFLD"
     CDS_motif       25197..25313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0008"
                     /evalue="8.20E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="751"
                     /protein_start="712"
                     /score="56.8"
                     /tool="antismash"
                     /translation="PTYNAPFAFRVRGPVDADALQSAVNDVVGRHEALRTVFP"
     CDS_motif       25515..25580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0009"
                     /evalue="8.30E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="840"
                     /protein_start="818"
                     /score="31.1"
                     /tool="antismash"
                     /translation="LHHIASDGWSLVPLLRDLSMAY"
     CDS_motif       25629..25667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0010"
                     /evalue="3.80E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="869"
                     /protein_start="856"
                     /score="19.3"
                     /tool="antismash"
                     /translation="QYADYALWQRELL"
     CDS_motif       25917..26006
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0011"
                     /evalue="1.20E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="982"
                     /protein_start="952"
                     /score="40.2"
                     /tool="antismash"
                     /translation="DIPLGTATAGRTDQALDDIVGFFVNTLVLR"
     CDS_motif       26058..26174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0012"
                     /evalue="2.00E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1038"
                     /protein_start="999"
                     /score="71.6"
                     /tool="antismash"
                     /translation="EGDLAAFAHQDLPFEQLVERLNPDRSTSRHPLFQTMLVL"
     aSDomain        26529..27767
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_AMP-binding.1"
                     /evalue="2.60E-106"
                     /label="HEP86_RS35160_AMP-binding.1"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1569"
                     /protein_start="1156"
                     /score="347.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEHVRNSPDATAVVDADGTLTFRELNARANRLAWLLISQGIRPE
                     QRVATLLPRAGEHIVALLAALKAGCCYVPMDPEDPEDRIALMLADAAPSFLLTDRENLA
                     RLRPGADPSIQVLVLDDPAVRQSLSRYAPVDPHSADRPVPLRPDHLAYVIYTSGSTGRP
                     KGVAVEHRNLSNLFHAHFAVFAPQVAAAGDHRFRALVTGPLTFDSSWEPVLWLLGGHEL
                     HLVHDEVRRDPEAMAEYIGAAGIDYMEISPTYCRQLMTAGMLSAGQPSQPRIVELGGEA
                     VDQALWSELRAISGTEGFNSYGPTECTVYVSYGAAAEHERPLIGRPISNNRMYVLDAGL
                     RPLPAGVVGELYLAGAGTARGYLGRPGLTAQRFVACPFGEPGERMYRTGDLARWSADGV
                     LEYMGRTDEQVKVR"
     CDS_motif       26715..26756
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0013"
                     /evalue="2.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1232"
                     /protein_start="1218"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LAALKAGCCYVPMD"
     CDS_motif       26979..27038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0014"
                     /evalue="7.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1326"
                     /protein_start="1306"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVAVEH"
     CDS_motif       27558..27647
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0015"
                     /evalue="2.40E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1529"
                     /protein_start="1499"
                     /score="48.6"
                     /tool="antismash"
                     /translation="PAGVVGELYLAGAGTARGYLGRPGLTAQRF"
     CDS_motif       27732..27797
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0016"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1579"
                     /protein_start="1557"
                     /score="35.8"
                     /tool="antismash"
                     /translation="YMGRTDEQVKVRGFRIEPGEVE"
     aSDomain        28089..28295
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_PCP.3"
                     /evalue="3.10E-28"
                     /label="HEP86_RS35160_PCP.3"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1745"
                     /protein_start="1676"
                     /score="89.8"
                     /tool="antismash"
                     /translation="EELLCGLFAEVLGVPEVGIDDDFFALGGHSMLATRLIARTRSVLG
                     AELGIRTLFDAPTVAGLADRLSQD"
     CDS_motif       28389..28418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0017"
                     /evalue="3.90E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1786"
                     /protein_start="1776"
                     /score="10.3"
                     /tool="antismash"
                     /translation="PLFCVHPAAG"
     aSDomain        28389..29090
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35160_Thioesterase.1"
                     /evalue="2.40E-40"
                     /label="HEP86_RS35160_Thioesterase.1"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="2010"
                     /protein_start="1776"
                     /score="131.3"
                     /tool="antismash"
                     /translation="PLFCVHPAAGTSWVYSGLLRHLALDQPVYGLQAHGLTEPDAAPES
                     MTEMVEAYLAQIRSVQPDGPYSLLGWSFGGVVAHEMAVRLQEAGQKVNSLVLMDSYPSR
                     VTADGHDTGRTEKSGSGTDRGDAPDAEELRQALFDSLGHQADATDGPLALLGEQGLAAM
                     VRVFARNSRLQSGFVPRSFRGDVLFFEATEGWVPGMQRPQAWRPHVTGRLAITPVRGAH
                     GELTRPEQLAQI"
     CDS_motif       28569..28643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS35160_0018"
                     /evalue="1.50E-15"
                     /label="NRPS-te1"
                     /locus_tag="HEP86_RS35160"
                     /protein_end="1861"
                     /protein_start="1836"
                     /score="49.4"
                     /tool="antismash"
                     /translation="QPDGPYSLLGWSFGGVVAHEMAVRL"
     gene            complement(29194..32079)
                     /locus_tag="HEP86_RS35165"
                     /old_locus_tag="HEP86_35165"
     CDS             complement(29194..32079)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537338.1"
                     /locus_tag="HEP86_RS35165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35165"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_248001456.1"
                     /transl_table=11
                     /translation="MTIDQLVDGLYHDDPPASARRVIVNYVHRLRTYLDRAHTAGREGG
                     AASGRDGGATVIGTMADGYVLRLPAERVDALLFGQLTLRARRAAAQGDPAYAASVLKGA
                     LGMWQGPALAGLPGPYAQEQRRALAEQRASATEHHLELSLACGRHEEVVPEILCALEAY
                     PYRERLHGALMLALYRSERSADALLAYDHARQVLADEMGIDTGPVLDGLHAAVLAGDRT
                     LLAVPATARTAAVPAEVQVWSAVPAPRAPAQLPAVPCDFTGRHDEVCTLVAALSGHASH
                     PVAVITGMGGVGKTALALRTGHAVMGSFPDGQLYAELRTPCGAPGDPADVLAGFLTSLG
                     VPHERLPASVSDRAALFRTLLSDRAVLVVLDNAATVAQVEPLLPGADQCAVLVTARALA
                     ALPAAVKVSLKGLDPHDSVELIGKVAGIRRIEEEPDAVAALAAASGHLPLALRAIGARL
                     ALRPAWPVATLLSRMSDEARLLGELRVGELTVEAVFEQSYAQLSPQRARAFLELSLPHC
                     VEFGVKGAAAVLELPEREVEDVLEALVDAVLLETRAPGRYRYHDLVGAYARATARVELT
                     DEELRQVVRRAADFMCASVAGAVLATQPLGVRLTSELRPRRSAGEDVGTGQEAVQWMRR
                     ALPTVAAVAEQAADSGDAEAVALAVDGLMLAPCFEESVPLGMLAPAATALVRSAVAYCD
                     EDVVGTAHYAAGVILKKHSSLDCLDRSRAHLLKALEIFGESPAPADGLRPFLAVLFTHA
                     MLAHLDAMCADFSSARAHAERSVEMAMITGDQGLVTRRRTLLLQIRAQDPGSRGDLARI
                     REQCRELADLLTCGNDVKWLIRVMTTEADTLLYGGRPAEAAALYRQVLPRARTTGHARN
                     ETECLYRLAEALLLTGDAHAAVDHARQALQGAQLTQEHLLMARSHQALGRALQAVRAEY
                     VDGEAAGHLEKAAELYRVLGLHTGSGAAVGQ"
     misc_feature    complement(32223..32233)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(32467..33036)
                     /locus_tag="HEP86_RS35170"
                     /old_locus_tag="HEP86_35170"
     CDS             complement(32467..33036)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009719777.1"
                     /locus_tag="HEP86_RS35170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35170"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_168482650.1"
                     /transl_table=11
                     /translation="MHARFPDFRLGKVLATSFTATLTERRGDAVERIPTPHRLVDWLAV
                     NGLAVESCTTAQLELARELRESIHAALTAAAIRDPLPASAVHVINDCSTQGRAAAILTP
                     ESNRQWRLSSASCVEDALGVIAADAISIIAGERDGKLALCASPTCQAAFFDTSQSRTRR
                     WCDMNTCGNRQKKARFHANQRKNAAG"
     gene            33140..34303
                     /locus_tag="HEP86_RS35175"
                     /old_locus_tag="HEP86_35175"
     CDS             33140..34303
                     /NRPS_PKS="Domain: Abhydrolase_1 (102-211). E-value:
                     6.7e-20. Score: 63.7. Matches aSDomain:
                     nrpspksdomains_HEP86_RS35175_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009480348.1"
                     /locus_tag="HEP86_RS35175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35175"
                     /product="epoxide hydrolase"
                     /protein_id="WP_168482651.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-15, bitscore: 56.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.6e-08, bitscore:
                     31.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSDVQAFEAHATDADLDDLRARLAAARLPEAETVYRAAPGPRRW
                     GQGVPLADLVDVVHYWRTGYNWRSFEERLNRIGQFRTTIDDLGIHFLHRRSARADATPL
                     IVTHGWPGSIAEFIDVVDELADPKDADAPAFHVVVPSLPGFGYSDKPATTGWGTEKIAA
                     AWVELMGRLGYSKFVAHGGDWGGNITTVLGGRFPAHVLGIHTTFAEAPPGLTTDGLTAA
                     ERKWTEDTRDFWRHRAAYAKQQATRPQTIGYSLVDSPVGLLAWILDKFAEWTDTEDSPF
                     EAISRDRVLDDITLYWLTRTGASSARIYYESHNSLDPELRVDVPSAITMYPRDIEKCPR
                     GWAQERYRQIVRWRSPETGGHFPSLEVPEYFVKDLQEGLAAVLAARR"
     aSDomain        33446..33772
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS35175_Abhydrolase_1.1"
                     /evalue="6.70E-20"
                     /label="HEP86_RS35175_Abhydrolase_1.1"
                     /locus_tag="HEP86_RS35175"
                     /protein_end="211"
                     /protein_start="102"
                     /score="63.7"
                     /tool="antismash"
                     /translation="PLIVTHGWPGSIAEFIDVVDELADPKDADAPAFHVVVPSLPGFGY
                     SDKPATTGWGTEKIAAAWVELMGRLGYSKFVAHGGDWGGNITTVLGGRFPAHVLGIHTT
                     FAEAP"
     misc_feature    34473..34487
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(35185..35200)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.58"
                     /tool="antismash"
     gene            35301..39215
                     /locus_tag="HEP86_RS35180"
                     /old_locus_tag="HEP86_35180"
     CDS             35301..39215
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042646.2"
                     /locus_tag="HEP86_RS35180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35180"
                     /product="DUF6603 domain-containing protein"
                     /protein_id="WP_168482652.1"
                     /transl_table=11
                     /translation="MLIENAYNVKGSELRNALVDFADTWATKLESLDYKEQEKLNFPRI
                     REFVKDLKDPESVYDPDGGVSPDGLDDIHSVLTWLPGNLFVGPDNKNRTDDPGPKVEAG
                     SARIIGSGILTKRTATFESLSRYSKKPMGAGMTRDGLTGVQGLIEAFTPDRLWPLKNAD
                     WEKKGAKYGIRPVGAASGALVGPSSSPARGMPHGVAFIVIGGVRLELTTWSDDGGYVLR
                     GVSAANIRMADLLDWLGETWDIAEEIPESLRSFRLQYLTIEVLTVPGVLEEWEVTAATE
                     VTFAGVTMDLLVCFRHSTPAGGASAFSLSADAGFTASVNGEDLRLWFSGAIARTVSGAW
                     ELSASLEEQSGVLSLAHLAAAFGVDVPADLEPLVPSFSSASFTYRLPAGSSAAGSLVLS
                     AVVGRVGVVVASEPEGAGSTVARLVAIRGDVTARLSELPLVGASIPWERDVLFTGVHFA
                     YSSGRWSREQVERLNTIVDGLDGGPEQRLPRLLGQALPPGALAWVNVTVGGKPRGPLIL
                     KLPDGGRAAAPGRGEGAWGGAGSAQSLVLGRERAEDGEDTAKGLELGGFAMGPVRFHHA
                     GLGYAQGRLFVSLDATMAVGPLTVELQGLGLGVDKDWNIAPVLRGAGVALERPGPPKVV
                     IAGAFTRLDLGPEFELAFAAAGRIEIQDLVSLQLMGSWARNRAGWDSVFAYAELVAGKN
                     RVNGLFTVGPVTFTGIALGFGINSTVRIPTASEISRFPLVNRLGARPSTPGGEVEKLTP
                     SQALNELVGPGGWVTPAHGQYWVAGGMEFTVYRFIQAKAIALVEWGEAGWKAMLAGRTT
                     LSLPPTTVPAESAASVPGAGINLSLGGPLGKVIVDFVFAYDSALGRFSMDTVIADGSYI
                     LDPQARLTGGISFYVWGKALPAQGVRKGFVLTAGGYHPQFRAPAYFPKPPRIGWVWERG
                     PVSIRAQAYAALTDGAFMVGGELAAVYDSGHGINLRAWFTAYVHALVQWKPFYADLALG
                     LSIGVAATVKVLFVRVRISLEVGVDLQLWLPPVGGRARVKVWFITFTLGFGSDRKGAPP
                     ADWQDFHVQLPAPSRTALKQGSELPDVSQDESAARAAADEPQLVRIEGFTAAVESALPA
                     SKITLNGKLFAGSDSARIDIRPMRLTGVVSEQIVQILDQRGNRYDWEKARWTVTATRES
                     LPQALWGKPLAHPNQALNQPGLVDDCLTGLTIQVPEPTRRRGVGPVPVEALDVDGLPPG
                     RMPLRDETVAGRSPVTDPHSIALIGDTLAEAGTAARRTRAHDALAALGLAPGSDGPLTG
                     TARLTGTSLTDAPLLTEAAR"
     misc_feature    37155..37157
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            39221..41413
                     /locus_tag="HEP86_RS35185"
                     /old_locus_tag="HEP86_35185"
     CDS             39221..41413
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS35185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_35185"
                     /product="hypothetical protein"
                     /protein_id="WP_168482653.1"
                     /transl_table=11
                     /translation="MPARPDLDVTFYDHLAPATTAGIYTITVEHCLTKDGRRLDATAEL
                     PKAEDRYEIRAARFHLDPSSVHATYPAAGAAGRYPHVLPHITLHRAILPWERQLLGRAV
                     PAPWLALLVLAEGETVDDPDAKGEFTTRTIGRLRNPAEAGTAGPELSGDINDDLPCRTI
                     DVPVDVFHAVVPREDELSHLTHMREVRTAPQLRDNGEVLSEGEYAVVAANRFPRTPGTY
                     AVHLVSLEGHLGRLASGALADSERVRLCSLWSWSFTNAPDGTLDPGTLLRGLVAPGAED
                     PENLALRHAPAAGSASTAEERYARTRLHHGYSAVAHRTLAGEDTYAWYRGPLTPLTAPD
                     LPGEAFQGPHTTADHALIYDREYGVFDVSYAAAWTLGRTIALADPDYSAEAVEARRALS
                     DRAATLAALGSDPHRARHDPDAPPAATALDELASAGFGRRLVQALRADLHPEPAPAPAA
                     RTARAEPATLLADPRARQSLSAVINARTPTMSEWLDRLALLRSVPFHHLVPDPRMLPPE
                     SLRAFRVDGAWIQALVAGATDVGVHTSVDRDLDPLLRERLARAHRRPIPAAGLLINSEL
                     VRAWPVFDLFATRGGEQVGELRRDHLAPDILLVLWDAVPDSVTLREPGQGIHFGINSER
                     RVSLRYLSGDDVGYPTGTEFPDPVSGRTVFDHLRPGRSGGLPDVLDLHGADGFVAALSE
                     ACGADDELSPGQFALELVNAPLEQLLLPAPTAEETA"
     misc_feature    39240..39254
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.1"
                     /tool="antismash"
     gene            41410..45849
                     /locus_tag="HEP86_RS35190"
                     /old_locus_tag="HEP86_35190"
     CDS             41410..45849
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012956.4"
                     /locus_tag="HEP86_RS35190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35190"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_168482654.1"
                     /transl_table=11
                     /translation="MSDTDLIVPVQVHALLANRKVRTLHPFHRYQPSFDRMLGTYPDTE
                     GRGAAEPEAFSGAKEVGGDETFEGVHVQWELPEALTDGLMAEDDGRTHFPLVPNRWLVV
                     RYSWVRGERKAVGWVVHSDYLYSDDDGALWNGYDTINSFVNPRKKDAPEVDWLGRAHRL
                     ADGPWQEPPGDRKLFLTAAGAGLPSFAAFEPYHENVFSFHDDLQDLKDPAHGDSYPPDA
                     TLSYLVVGWYSDTDEDILNVAAGIPGLLPPGPDGSSAADVIAALGWTVAGRTALVQGGM
                     GTATGHDVTNVLDHQEDTYYLSEKAPVRSDRITVDLGSVQQVSSLHVLVGDPDGQHSLP
                     AVRVQTSVDNVNWPSAHYQDFDAGTPVIEYTPERPVTARYVQLWMLESGSGPAAVRRLE
                     ATAAPQATRSLYHGTALGLEWEREGEAPDDARPDATHTKIAFGHSTGEAATMLIGHQTR
                     SPRTAQLFSALYHGTLDTFDGAAGDRDLAEVTHRSWFSGSDGGHTWQIVPRDDREPDSG
                     RSGTVDDDPFPLDELNAAQAEYDHLLRQLTEHQWRVWALYWLRNLPDVERPGDLPSDFD
                     TTCDELLAPDGDGPANQAKEAQARLRELRDHIPQAAAGQDLQDAIDAWATARGLADRLQ
                     LKRLPQDSFYKPADPVVLIEGTGGGTVPLTRDRDNPLPCRVPSHLLSEVKIGANWTAPP
                     ASPPDPGITGLPDACTDLLKEFALLDEAARTADNGHTALHTITQNPATHARGPLAEYCA
                     PWRQPWLPMLLMWKLNYFPTPYHTADGYHWTFTAPPPGSELDTYSYLWNGTGTLKADFE
                     SEGDVLNRLFRSRAYLAPTTVYVLREQLSRYRAGYPSVNTAGLAALRRELEPLDVLSQT
                     LDGFNDWLLQLDGGAQVPTEPEIAALAGEQNHVPDPAGGPHQKRFQPVRAGQFFLTDLR
                     IVDHFGRCADLVTSGASGNWYDQYPLKTPSVTPSHDLYTEPRLINPERFVQLPPRILQD
                     TRLAIAQEPSGQADGLAGLLLVNYLDRTLGVYGTTGQALGELRTVTTSGDTRVAVYTPL
                     PHSPYTGHTDPRFATDHPQLAAFLTGLLDRDDSAGAFGALLATIDKSLRALVAPAAEDS
                     RLPGLLIGRPVALVHATLDLELHHPLPADPSWDTVLHPLGASADDDTWAIRLGDPHALD
                     DGLIGYFSADPGQPVDYGLLRALDPALDHDYLQATTNGSDLALPVRPATRPCTRHVTLL
                     AHPHLPVHATTDILPVHSLRLDAERVHQALAAVRASFRLNPLLATTRDRRSLGTTMTED
                     PDHPLSNISGSGEPAAEFRSLDVPAVGSTITLDLGAVQQLTGYSLRTGTAGGGSWPGTP
                     VLESSVTGDDDGWEPRAFNARQPVNEHTLAAPVPARYLRLRLTTDADGIFGMRTFRATC
                     TPDDAALVVPPLSARHGTWSWAQPQATGTEQLDWDERLLIPADHLAHPDDAMPTARAGY
                     LQLHPSTRQADPEPTSQS"
     gene            45875..46384
                     /locus_tag="HEP86_RS35195"
                     /old_locus_tag="HEP86_35195"
     CDS             45875..46384
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS35195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_35195"
                     /product="hypothetical protein"
                     /protein_id="WP_168482655.1"
                     /transl_table=11
                     /translation="MTESAATAPLRYTLTTFPPVLTQAAPDRPSQGRLEIKVFRDPQAV
                     QTTAGCRSITVEVPTGDRPDALTDRPDRIDATYGAPHGRTWHIRKSISHSDRTVFVCTP
                     ENPRHEAVFNDTATFTLILDRIPLTGSPSTVGLRITDESATGSETHTRRSTDLRLTVQR
                     APDGGS"
     gene            46514..47860
                     /locus_tag="HEP86_RS35200"
                     /old_locus_tag="HEP86_35200"
     CDS             46514..47860
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012956.4"
                     /locus_tag="HEP86_RS35200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_35200"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_168482656.1"
                     /transl_table=11
                     /translation="MYPTTSDAPLSVTSQTTPPTHFTVSTAEEVKRGTVFLTFAKPAAA
                     PDVTCAEISVSLPRGDAATDLVNDEARANYTLIDDYPRDSTGAAWSIHRLPAAPVTTAP
                     EWGEAPGHEFTNIFDPRDDFYYRTTGLVPKDSALVVDYGVDQDITTLDIATGFTNGRNK
                     VQMLLLQSSMDGLHWNNVDEHPVQDTLRIERTFDPPLHARYLRIFTIVEPSNEGYAVVR
                     RFLANQGTRTRSADDPVTFVCTPDDGAAVFDASRDFTLILSNIPINQTLGTAALEITQT
                     VIAGGGEVRHTTSLDGFEKADNAFVFENFSSKQPRVDNGDHVTLHWTGSPANSDYHLSW
                     DDRTERISVPAGRDCSFGTADLPRFAGLSRTTTFVLDAQTINSSGQTVHHYQSTTVTVA
                     DPDIEAGSLTATDRLAVRAGGTDTFLARSDEAGTHALTAHAEGDVTIIA"
     misc_feature    complement(48089..48101)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     misc_feature    48218..48232
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.94"
                     /tool="antismash"
ORIGIN
        1 cgccgtccat ggttgccgcg gtacatcaca tctccctcag ctctctgcac cgcctcttcc
       61 agggcgaaga cttgcccgtc gccgcctgga ttcgccacca acgcctcgaa cgtgcccgtc
      121 gcgacctcac cgatccggca ctgcgtcacg aaacgatcca cgaaattgcc gctcgttggg
      181 gcttcagccg cgccgctgac ttcacccgtg ccttccgtac ccactacggc atgccgccca
      241 gggactgccg gcaccgagca ttcggtctcc aggtcgagac gcattgctaa gccctcagca
      301 ccccttgctg atgacctccc cggcagctac ctgcattgtg gaatcgcggc gccggcctgc
      361 tggtcggctg acgcgcatac acctagtcgg aaaggacgtt caccatgcgc gcgacgcgca
      421 tcacattcat cctggcgggg ttactgctgc cgctcgtcgg tccgttgagc gccgctgaag
      481 ctgccccctc caacccgggc acacccccgg cgcaacgcac gtccgccctc gtcgatcgcc
      541 accaggcagt aatgaaagtc gccgataggg cgtgtgtcac ttcgggaggg tacggcggcg
      601 cccggttcaa gcggctcacc gggcccgtga cgaagctcaa ggtcacgctg tgggcgtatg
      661 acggagtctc tgacggtcaa cacgtgcgtg tccggctcgt cacgaagaac agcaagggcc
      721 agaggcacta ttggaagtgg cacaagactt cttccgagaa gacgtggcat acgactgccc
      781 gcgacgtgta cggcattttt gaagtgggtg cccaggtggc acagttcaag ggcgacaaac
      841 gcctggatat gtgcaccgcc tggaagtagt ccgcgcccgg caagtaactc agtgtcggcc
      901 gcgccaggtt cccagaccac ggagaacggg agatcattca gctgatcctc ctcgtgacgc
      961 ctgtcccgca gccgcccctg gtgccgcccg ttcggatacg gagcggcgcc gtccaagagg
     1021 cgcaggcgcg caaagcgtgg gtcttctcag cgggccaggg cgtgacccaa gatgtcctcc
     1081 tgcggaaagc gcgcgaagga gccggtcacc ggccccgggc ggctcgccgg acgggctgcg
     1141 cacgccggtg ccggaggccg tccggcaccg gcgtgcgcag cccgtaccag ccggcgtgag
     1201 acacctgtca ggagaacagc atgcaccgcg cccccagacc cccttcccgc tccggcgccc
     1261 cgcagctcga cgccgtcatc gtcggggcgg gcttctccgg cctctaccag ttgtaccggc
     1321 tgcgcgcatt gggcctgcgc acccgcgtcc tcgaagcgtg cgaagacatc ggcggaacgt
     1381 ggtaccggaa ccggtacccc ggtgcccgct gcgacgtcga gagcacggcc tactcctttt
     1441 ccttctcgcc cgaactggac caggagtggg agtggagcga gcggtacgcg acgcagccgg
     1501 agctcctgcg ctacctccat cacgtcgccg accgcttcga cctgcgcaag gacatcaccc
     1561 tgcggacccg ggtgacgggg gcggtgtacg acgagggcgg gcacacctgg caggtcacca
     1621 ccgacaccgg agagacggtc accacccggt tcgtcgtgct ggccacgggc tgcatgtcgg
     1681 ccgtcaagga accggacata cccggggccg gcaccttcgc cggccgatcc ctgcacaccg
     1741 ccgactggcc gcatgaggac gtcgacctca ccgggagacg ggtcgccgtg atcggcaccg
     1801 gatgctccgg catccaggcc atcccgatcc tcgccgagca ggccgccgaa ctcacggtct
     1861 tccagcggac accggtctat gcgctgccgg cccgcaaccg gccgctgtcc gccgcggaga
     1921 ccgccgaact caaggccaac tacccggagt tccgcgccgc ccagcggcgt tccaaggggg
     1981 gcaccctctt cgagccgccc acccggtcgg ccttggaggt ggacgaggag gagcgcaggg
     2041 ccacctatga ggagggctgg gactcgggcg tactcagcgg cctcctgcgc acgtacaccg
     2101 acatcctcgt cgaccgggac gccaacgaga ccgtcgccga gttcgtccgg tccaagatcc
     2161 ggtcgatcgt caccgacccg gagacggccg agacgctctc gccgagcacc ttcccgttcg
     2221 gtaccaagcg tccctgcctg gacactggct attacgccac ctacaacaag ccgcatgtga
     2281 gggtcgtgga cctcaccagg accccgatcg tggagatcac accgaggggg atcaggatct
     2341 cggaccggga acacgccgtc gatgtcatcg ccttcgccac cggcttcgac gcgctgaccg
     2401 ggtcccaggt cgccatggac atcgtcggca agggcggcac caccctcagg gagaagtggg
     2461 ccgacggccc ccgaaaccat ctgggcctgc tctcggccgg cttcccgaat ctcttcaccg
     2521 tcatcgggcc cctcagtccg tcggtgctca gcaatgcggt cgtggccatc gaacagcatg
     2581 tggagtggat cagcgactgc atcgcccacc tgcggcggaa cgggatcacc gagatcgacg
     2641 ccaccccgcg tgccgaggcg gactggcgca cccatgtcgc cgacctcgca gcccagaccc
     2701 tctacccgtc cgtcgactcc tggtacatgg gggcgaacgt gccgggcaaa ccgcgggtct
     2761 tcctggccta cacgggaggc ctggagcggt accgggcgga gtgcgccgcc gccgctgagg
     2821 acggctaccg cgccttcgcc ctgtccggcg gcgctgactg agagcccgtc cccggccggc
     2881 gaacgggtca ccgatcgccg gccttccgca cccgccatcc tcacgccttc tcgtgcgtgg
     2941 gccaattgct gggtggcggc accggggagg cgagccaccc gcgctcattc caggcgttgg
     3001 cctacacgga cagacgtccg gcccgtcgca gccaggaatg gcagcgctgg aagaactccc
     3061 ggtatcgggc gacgcgcggg gtgcgccaca tggttgcagc gccagcagac cggtcagcac
     3121 cgccgaggtg accacctatg tccggtcggt gaaccgtccg gtgcggcccg ttgggggcat
     3181 cgtcggtgag ccgtggggcc tggcaggagg ccgagaccag tcgctgatca cagtcgggcg
     3241 cctctgcgcg taaggagtcc gtcgtggacc ggggtgcggt cggcgtgggg ccgaatgagt
     3301 tccgtaatgt gcggcaaagg atgaattgcg cgtcgagctg catacggtga gtcctgggcg
     3361 gcgatcatgc cgcaccggcc accgtgaggg gatcgatgtg gagggtagtg accgtgatgg
     3421 tgagcctcgt cgtgacaggc cgcagcgaca gcctgacaag gcggccgaca gcagcccgcc
     3481 accccgaggg agctccgcac aacgacgggc cgccggcgcc gccccaccca ccgaaagggc
     3541 tgccgagccc catccaggtc gtcgccggcg cctcgccgca ctgctgagca gtccgccgcc
     3601 gggccccacg cggtcgggct tctggcgcag tccgctgcgg gggccgtggc tgacgtcggt
     3661 tttcgggctg attctcctgg tcggcatcac cgtgctgttc gtgaccgggc tgctgtccta
     3721 cgcttcgtac aacccgaatc tggcgccggg caacgacaag acgccggaaa agggctggct
     3781 cggcttctat ctgttctcct ggccgaccag cccgtactgg ctctaccgcc tcacccaggg
     3841 aatccacgtg acgctgggcg tggtgctgat cccggttctg ctggcaaagc tctggtcagt
     3901 cgtccccaag ctgttcacct ggccgccggt gcgttcactg agtcatgcgc tggagcggct
     3961 ctcgttgctg cttctcgtgg gcggggtgct gttcgaattc gtcaccggcg tgctcaacat
     4021 ccagctccac tacatcttcc ccgggtcctt ctacaccctg cacttctacg gcgcctgggt
     4081 cttcatcggc gccttcgccg tccatgtcgc cttccggatt cccaccatgg caagggcgct
     4141 gcgcagccgt cgcttccgca gcgccctgcg tacccccgct gcacgcacga cacccgaagc
     4201 ggcggatgac accggcctgg tgacccccca ccccgcgccg cccacgatgt cgcggcgtgg
     4261 cgcgctcggc ctggtgggcg ccggctcgct ggcactgctc gtcgtgacgg ccgggcagag
     4321 catcggcggg gccctgcgca agaccgcgtt gctggcaccg cacgggaagg agccaggaaa
     4381 gggccccaat ggctttcaga tcaacaagac cgcggcggag gtaggtatcc gcgcccgcga
     4441 catcgggcct ggctggcgcc tggtcgtacg cggccccggc cgggagcgga tcttcacccg
     4501 tgcgcaggta ctggcgctgc cgcagcacac ggcagccctg ccgatcgcct gcgtggaggg
     4561 ctggtccacc gacgacctgg actggagcgg tgttcggttg gccgacctgg cagccctggt
     4621 cggactgcgg cagagcccgc cgggcgtgtt cgtcgagtct gcccagcgcg gaggagcctt
     4681 cagctccacg cacctgcgtg acaaccaggt gcgtgacccc aggtcactgc ttgcccttcg
     4741 ggtcaatggc gcggacctct ccttggatca cggctatccg gcgcggatca tcgtcccggc
     4801 caaccccggt gtgcacaaca ccaaatgggt cactcgcctc accttcggag cagcacaatg
     4861 aagggcttcc gcacacgcta cggcgcatcc cccctgcacc tcttgctcgt cctgtgctcc
     4921 ttcgccctgg ccgtctatgc gggactccgg ttgctgaagg gagacacgct cggagtcgtt
     4981 ctctggttcg tgggcgccgc gctcctgcac gacttggtct ttctccccct ctacaccgtc
     5041 accgaccgag tggtgcaacg cgtcttccgg cgcagaaggg acgcgacgga ccgttcgcac
     5101 tcgctgacag gccggatcaa ctacctccgc gtgcccgctt tcgtggctct cctgctgctc
     5161 ctcgtctggt atccgctcat cctgaaccgg gtcccgggct tcacctcgta caccggccta
     5221 caggccgaag tgttctgggg ccgctggctg ctgatcacgg ctgccctctt cgcagcctcc
     5281 gcagtgtgtt tgctggtcgc catgtggcgt gggcattcgc cccggccgag agcgcacgaa
     5341 gcccctccca aggcgcccgg ccgacaccag gcgtaaccga ggccgccagt tccgagaaag
     5401 ggccgcctgt tccgtgagca ccgaagagca tgcgccagag cagccgctgg gccccggtca
     5461 gcggcacgag gacccgtatg cgcacgcatt gcaagacggc cgcggtcccc tctacatgcg
     5521 ccgtatggac ggtggagttc tgtcgtcaga ggtggaccgc tggtgtgccg ctccggaccc
     5581 cgccgacatg agcgttctgc ggcggtgcaa gggggccgtc ctcgacatcg gttgtggacc
     5641 ggggcggctg gtcagcgccc tccgggcgct cggccacctc gtgctcggca tcgacatcaa
     5701 ccatgccgcc gtcgcgcgga ccgccgacac cggaggcgcg gcgctgtgcc ggtctgtctt
     5761 cgaacggctt cctggtgaag ggctctggaa tacggcgttg ctcatggacg gcaacatcgg
     5821 gatcggcggc gacccggctg ccttgctggt gcggatcggg agcctggtgt cgccccgtgg
     5881 aagcctgttg ctggtggagg cggccgctca tgacgtccac gaacggttgc atgtgcagtt
     5941 cgacgacggc cgtggccgcc ttggcatgcc cttcccctgg gcccgtgtcg gtgttgccgc
     6001 gttgcgtcgc acggcagcgg ccaccgggtg gcagccgggc gaacactggt cggtcggcga
     6061 ccgccacttc ctcgaactga agcggtccgc cggctctcgc gcggcacaca cgcgacgtca
     6121 aggctgaggg aagccgcagc agcgggcgct gcgttcctgg atggcggctc ccggacccga
     6181 cccaggccgt gcggtggtca ccagccggtc agcaacagat ggttgacgag gagggcgagg
     6241 acggcctgtg tggccagcca ccgagcatga gcccggcgtg ggagcagcgc gcaggcgggg
     6301 agcagccaga ccgcgaaggt cagccagatc cgttcggtct ctgccttgct cattccggac
     6361 agatccgcga gcagcatcat gcacaacgcc gcggcgacca gcaccgacag cgcaccacgc
     6421 ccggccggtg acctgcgccg catcccccgc acggccggcc gcagaggtcc ggcggctcgg
     6481 cacagacccg cgaccgtggc caggcccact gtcagcacct gggcggcgag gttggcccag
     6541 atgaagtagc cgtacgggcg taccttggcg gcgccctggt agtagcgctc gacgagggtc
     6601 gtgtagccgt caagccacca gaacccggcg gcggtgaagg ccgccaccca gggcagtact
     6661 cccaggagca ccagcggaag ggggcgggct gaccgggcga ggaggaggac ggcggcaccg
     6721 agcacgacga ggacggtcag gccgtaggag aggtaccagg caagccccaa gagcagaccg
     6781 gcgcccagag ccgcgaggcc gggcatgcgt gtggtgcggc cggccgccag cgcgagcagc
     6841 gcaactgccc aggcggagac accggcgaag tagccgtcgg cactgacacc gatccacacc
     6901 gccgccgggg ccagcaccag gaacggggcc gcttgccggg ccagttgctc accacacagc
     6961 gcccgcacgg ccaccgcgac cgcggctgcg aacgacgacc cgacggtgat gcaccaggct
     7021 gccgcccagg cgccgccgct caacccgata cggtccaggc cgacgaacgt cagcagtgcg
     7081 ccgggcgggt gaccggccac atgcgccggc cagatgtgag gcgagcccac caggatgtgg
     7141 ttcgtgaagt cccgcaggaa agcgggcaca tcgtgcacgt ccttcaccga ctgcaggtac
     7201 tccagactgg tggtcagccg ctcggcgatc ccacgccccc aaccgtccac gagcgccagc
     7261 gaccacgtcc atgccattgc cgcgccccag acggccggca ccagcacccg ccacgacagg
     7321 cgccgcgcag tcggcgggcc gtagaccacc accagcgcgg cgacggcgag agccgccggc
     7381 gtccccgggc cgatatgcgg cagccaccac gcagacagcg gcggccaccc cagccgcaga
     7441 accccctccg caccgtaaac ggtcctgttg aggagtcttc cgatgaccac cgccagcgcg
     7501 agcagcacga ccgcggccac cactgcccac acatcgcgtc ggcactcccg cttccgcgca
     7561 ctcatcgtca ccgcgtcacc gtgggcgggg acggctgacc gttcgctgac cttacggttc
     7621 gacacagcgg atcacatcgt tcgcagtatg ggcggctcgg cccggccagc ggtgttcggg
     7681 gtcttcgtag tcgtggcggc agccttcgtc ccaggtggtg cgctgcttgc cgtaggcggg
     7741 gaggccgccc cgggagtcct gccaccgtgc cgtccacggt gacgcaacgc tgcccatcgt
     7801 gatggcccgg cgcccgagcc ggccgcagcg gcacgaccgg tcgccgacga ccaccccgac
     7861 agccgaacag accggtgggg gagagccggt gggatcggcg gattgcggcc cgcgcggttc
     7921 atggagccgt ggcgggccgg tcgcgcggcg gggcgccggt caccggggtc tggagcaggt
     7981 agcgatgtgc agcgcagtgg ccggcgaaag cgctccaggc ttccaccagc caactgcccc
     8041 tggtttcctg gtcgttgtct gcgagtcgcg tcacgtcgcc ggacggcagc gcgctgagcc
     8101 tcggcagcag ctgcgctgtg agcagggtgg agagcgctgc gcgtactcgg agtgtcggct
     8161 gttgacggtg ctgcctcaca gcccggcgag gcacggcctg cggcgggcgg cttacgaatt
     8221 cctgatgctc cggcgtcgtt cggtcgccgg gcgggccggt ggccgtacgg tcggtggcat
     8281 gttgatcctg gtcaccggag gcgcgggctt catcggctcg cacgtcgtca ccgccctcac
     8341 cggcgccggg cacggtgtgc gcgtgctcga cgcgctgttg cctgccgcgc accgcacgtc
     8401 cccgccgatt cccgacgggg tggaccggag acatgcggac gtccgcgacg cagcggccgt
     8461 ggccgaggcc ctgcagggtg tggacgccgt ctgccatcag gcggcgatgg tcgggctcgg
     8521 caaggacttc gccgacgccc ccgcctacgt gggctgcaac gacctgggca ccgcggtgtt
     8581 gctggccggc atggccgagg ccggggtgcg gcgtctggtg ctggcgagtt cgatggtggt
     8641 ctacggagaa gggcgctacg agtgcccggg gcacggtgtc gtacggccgg agccgcgcaa
     8701 ggtggccgac ttggaggtgg gacgcttcga accgtcctgc ccgaggtgcg gtgagccgct
     8761 cgcccccggc ctggtggccg aggacgcccc gcttgatccg cgcaacgtct acgccgccac
     8821 caagctcgcg caagagcacc tggccttcgc gtgggcgcgc gccgtcggcg ggcgggtggc
     8881 cgcgttgcgc tatcacaacg tgtacgggcc cgggatgccg cgtgacaccc cgtacgccgg
     8941 agtcgctgcg ctgttgcggt ccgcgctgga gcgcggtgag gcaccgcgtg tgttcgagga
     9001 cggaggccag cggcgggact tcgtccatgt cagggacgtg tcccgggcca acctcgcggc
     9061 cctggacggt ctgcccggtc tgctggaggg gagcacgcgg gcgtacaacg tcggcagcgg
     9121 cgagccgcac acggtggggg agatggccgc cgtcctggcc gaggcgcacg gcgggcggat
     9181 gccggtcgtg acgggggagt accggctcgg ggacgtccgc cacatcaccg cctcctcgcg
     9241 caggctgcgc gacgaactgg gctggaagcc ggaggtcgcg ttcgcggagg gaatggcgga
     9301 gttcgcggcg gcctcgctgc gagccggctg atcaggcggg ggctgcccgg tcctccccga
     9361 tctctcgcgc agccgccgca cgtgggcggt gacggtggac aggccgccga actcccagcc
     9421 ccacactcgg cgcgtcagct cctagcggct cgtggcccgg cctggatttc gcagtagata
     9481 ggccagaagg tcgaactctc ggacagtcag ggagagttcg gcgctatgtc gggggcgggc
     9541 gatgggggct aaggcgaggg atccggccgg tgtggtctgt gcggcggcag agcggcggcg
     9601 tgggacacgg tggcgggacc gtcggcagcc acgtcgacgg cgaagcccgc ccggtgcaga
     9661 cagctggcga cgaccctcgg agacggtggg gtcgtcgtcc acgacgaggg cggattcacc
     9721 gccaccgagt ctcccaccgg cattcgaccg tcggcggaag cgtcggagga tgtcagcgat
     9781 ccatgaggct tctaattccc atttgcctct tttgtctccg tagggtgggt ggcatgatcg
     9841 aaacatcccc ttcttcggct gcgcctgtgg acgtggtgct gccctgcctc gacgaggccg
     9901 aggctctgcc gtgggtgctg ggccgaatcc cctcgggctg gcgcgcgatc gtcgtcgaca
     9961 acggctccgt cgacggctcg cgggacatcg ctcgcgctct cggggcgcat gtcgtacacg
    10021 agccgcggcg cggcttcggc gccgcctgcc acgcgggcct gaccgccgcc accgccgaca
    10081 tcgtctgctt ctgcgactgc gacgcctccc tcgaccccgc acttctgccc gctgtcggcg
    10141 ggcccgtcct cgacggttcc gccgacctcg tactgggccg ccgcaggccc gttacgcgcc
    10201 gcgcctggcc actgcacgcc cgcctggcca acctggagct ggcccgtctg atccgccggc
    10261 gtaccggact acggctgcac gacctgggcc cgatgcgcgc cgcccgccgt cagtccctgc
    10321 tcgctctgga cctgaccgac cggcgctccg gctacccatt gcagatggtg gtccgtgccg
    10381 ccgacgcagg ctggcgggtg gcggagacgg atgtgccgta tcgcccgcgc acgggccgct
    10441 caaaggtcac cggtacctgg cggggcacct ggcaggcggt acgggacatg cgcgctgtcc
    10501 tcgccgagcg gcccgtcacc gacccggtgt ccgcggcaac caccccagga accggacgat
    10561 gagcgcccgg ctccctgcca cgctgctggt catcgccaag gaacccgtgc cggggcgcgt
    10621 caagacgcgg ctcaccccgc cctacgcgcc ccaggaggcg gccgctctgg ccgaggcagc
    10681 cctcgccgac accctgcaca cggtgctcaa ggtccccgtc cggcgccgag tccttgttct
    10741 cgacggtgtt cccggcccct ggctgccacc cggcttcgat atcgtgcccc agggcgccgg
    10801 cggcctggac gagcggatcg cggccgcctt cggccactgt gaccgcggac cggccgtcct
    10861 gatcgggatg gatacccccc aactgaccgc ggacctcctt gcgggggtcg gccgagacag
    10921 cgccgatgcc tggttcgggc cggccgcgga cggcggattc tgggcgctgg gtttggccga
    10981 cccggcgcac gccgcggccc tcgtgcgagg tgtgccgatg tccaccgacc gcaccggggc
    11041 gatccagcgg cgccgccttg ccgaggcggg gctgagcgtg agcgaactgc cggtgctgcg
    11101 cgatgtggac accgccgccg acgccgccgc ggtcgctgcc tgctgccctc ctggctcgcg
    11161 cttcaccacc accctgaact cgctcgcgga agccgggcgg tgagcggcac ggcaagcggg
    11221 agagacccag gccctcgccg agtgggcaac gcagactgcg gcccgacggc atcccccacc
    11281 ggcccatccg gacggcgccg gtagggaagg ggaacttctg ccgctggacg tcgagcgctg
    11341 ttgcgccgcc cccgacgccg ccgacaccag cgttctgcac cgttgcaccg gccctgttct
    11401 cggcatcggc tgcggaccgg aacgtctgat ggcagccctg gccgcccagg gcgtgcgggc
    11461 gctcggcgtg gacgtcagcc cggcgtagtg gcccggaccg ggcagcgcgg gggtgctgcc
    11521 atgatcgtcg ccgccgggct ggcactgaac gcggccatgc agctccggca cgaccggtcg
    11581 gccgcggacc gggccccccg cgcgatcgaa cgggccctgg accagtcctg accgcacgcc
    11641 ggaccgggca ctggccgagc aggacatcgc ccggctctcc ccgctcaagc accgcaacct
    11701 gaacctgctc ggccgctaca gcttcaccgc ctccaccccg gccgccggcg ccctgcgccc
    11761 gctgcgcgac ccggacgcgc ccgacctgga cgaggacgac gacggcgggc aggagtgagt
    11821 gtcaggagtt gatcggatca atccgtgacg ggcaggcact cggcgagcag ggcgacgatg
    11881 tcatgccagg ctcgttctgc gtgccgtggg tggtagccga cgccgggacg cacggtgtgg
    11941 tcgaccggtg gatggtggaa ggcgtgaagg gctcccccgt aaaccacgag gcgccagtcg
    12001 acgcccgcgg cctgcatctc cgcggtgaac gcgtcccgtt gcgcgggcgg catgatcggg
    12061 tcttccgacc cgaccccgac ccataccggg cagcgaatgc gcgccgcctc gcccggtcgg
    12121 cccgtggtca gtgcgttgac cgtcgcaatc gcgcgcaggt cgacgccatc gcgaccgagt
    12181 tccagtgcga ctgcgccccc ggtgccgtag ccgacggcgg cgatccggtc ggggtcggcc
    12241 cgtggttcgg cacgcaacac gtcgagcgcc gcatgaccga tgtcccgcat ccggtcgggg
    12301 tcggcgagca gcggcatgca acgggccaac atttcctctg ggtcttccaa atagcgtccg
    12361 ccgtggaggt cgaaggccag cgccacgtaa cccagctcgg ccagagcctc ggcccggcgg
    12421 cgctcgacat cgctgagccc tatcccctcg ggtccgatca ggactgcggg ccggcgcccg
    12481 gcaccggccg ggagggcgag gtatccgatc atcgtcaggt tgtcggccgg gtattcgacc
    12541 gtacgggtgg tgatcgtcgt catacgactg gacggtaatg actgttgcgc ccgctcgggg
    12601 tggtgttcac cgatggcaga cagcggtctg tcccgactgc acatcacccg gatgcatcgg
    12661 cccgcctgtc gtcaaacgat cgaatgacga caggcgtggc gggcgtccaa tgaacccgtg
    12721 caatccgggg gttcgcggcg gcgcgaatcc aatcagaccc gatggtgatt gctgacaggg
    12781 tttgacgaca gatagggccc actcctccgt acggaagggg cccttcagtg gcgaacctgg
    12841 tctgcaagcg ggtctcgacc gaccagcagt cgaccgcccg gcacccgcgc accggcgagc
    12901 tgctgtccac cgtgaagttc atggtgcaga ccctcgccgc cgccggcgaa ctccaacgcg
    12961 acctccagcg cgaactgacc tacgacggcc tgcgcgccgc cgaggccaag ggcaacaagg
    13021 gcggacgccg ccccgccgtg gcggccgcga agaccgacgc catacgcacc gtgtacctgg
    13081 aaggccgctc ggtcgccgcc cttgcccgcg agcacggcgt cagcctcccg gacggtgacc
    13141 ggacagcgag aactcacccg cgcccagccg tgaggtgggc cgccgcgtac ggctcggtcc
    13201 ccggcggccc gggtggcgac ggcgctgaca ggaagcgggg ctgggcggag tagctcgggg
    13261 tgtcagctgc cgaaggggat gtcccgaggg gtggccatcc ggcgcgtgtc cgggtgggcc
    13321 ttcacgtagt ccgtgaggta cgagagcgac tcccgcaccg cgctgtcgtc cgtgccgcag
    13381 cccttcgggc cgctgacgcc gtccgggtag cacgacatcc ggttgccgta gatcaggctg
    13441 tccacggcgg cgctcccgcc ggaggcgtcc agcagggtgg cggcacggtc cccgtccccc
    13501 ttgcccaccg tccagccgac ggtcaggccg agctctccgg tgtcccgggc cttcctgccg
    13561 gcttccagct ccttccggat gctgccgaac ttcaaggcca tgttgaacag gccgttgtcc
    13621 atcacgcgct ggttgccggg gacgttcggc ccgtgctcgg cgaagccgtc ccggacctgc
    13681 gcgtagtcgc cgctgaagct gaccgcttcc ttggagttca ggtcagcgag ggcggtcttc
    13741 cagccgctgc cgccctcctt gccgtagaag ccgtagagca cccgaatgcc cttgctctcc
    13801 agcttcttgc gcgccatgtc ccgcagcccg gccacggagc agtggcgcca cttggggtcg
    13861 ttgctgtcgc accagtcggg gttcttcatg tcaagccaga cgaaggaggc ctgacgccct
    13921 tgctcatgct ccttcgccac ctggtcgaac atggccgaca tggggtcgcc gtagctggtg
    13981 agagtgccgt cgtggtcggc ccaccagccc ttgcgccagg ccgtcgcgtc catctccagc
    14041 gcgttggccc cgttctcgag cgccctggtc acaccgcccg tggtcagcac ccggtgggcg
    14101 atggcccagg tgggacgctg atcggtggca ccgggcgcgg ccttggaggg cttgtcctcc
    14161 ggtacggcca ttgcggctcc ggtgcccagg gtggctgcgg agacgaccag ggccagcggc
    14221 agcagtacgg cgcgaagccg gcgtggggag gccatgagga cggtcctttc cggttgcacg
    14281 ggctacgcgt ggtggcagcc cgtgcggcgt gtggtggctg tctgcgctac aggcagacgg
    14341 cgggccaact gcccgccggt gcagcactgt acggctaagt tacccatcag taaataggct
    14401 gccgtccgta cgcagtcgcc ccccgtccga ggtaagggag cggaaacctg tcggcggtgc
    14461 ccgggagtgt ttgattggcc aggcgagcgc cacctcgttc ggtgtcagtg ctgtctcagg
    14521 cgctccgcgc tgggcccata ccccgtcgcc gttctgcgtc agcccttgcg cttccaacca
    14581 gcgccgcgcc ccctcgggtc cacgactggc gcagacacca cccccggcac ggcctgtgcg
    14641 aggcccggtg cggctgccag gctgggcgga caacggttcc ctagacctct ggagcggaaa
    14701 cgtgcaatcc cctttgaccg cggggcaact ggagatctgg atatcgcagg tgctcgaacc
    14761 gggcagcccg gtctacaacg tgggtgacta ctacgagatc accggcgccg tcgacgcgaa
    14821 gctcctcgaa gcggccgccc gcaccgccgt ggacgaagca ggatcgctcg gcgcacggtt
    14881 cctcgtcgcc accgacggta cgccctacca ggaactgggg cccgcggaat ggtccttcga
    14941 ggtcctcgac atgagtgagc ggcccgaccc cgacgcggag gcggtggcct ggatgcgtgc
    15001 cgagatggcc cgcccggtcg acctgacccg cggttctctg ctggccggtg cgctgatcaa
    15061 ggtatcgagg gaccgccact tctggtatcg ccgtttccac cacatcatca cggacggcca
    15121 tggaactgcc gccgttgccc gcaggaccgc ggccctctac cactcgatgc acaccggttc
    15181 cccttgcgaa cccaacccct tcgcgccggt cacggccgcg gtcgagcacg accgcgccta
    15241 ccgggccggc cggatgtatg cggccgaccg ggagttctgg gagaaggtcg cgctcgactg
    15301 gccggccacc ggccggctcc gggcggacgc tccgcccgca cctgccacct tgcagtacag
    15361 ccaccatctg ccacggcagg tggtcgacgc cgtccgagcc cagagcgagc ggctggaggt
    15421 gtccaccgcg cgcttcctga tcaccgccgc cgccctctat ctgtggcagg tcaccggcgc
    15481 cgacgaggtg accttcggct gttccgcgac gagccggccc acccgcctgc tgcgcaatgt
    15541 cgtcgccccg atggcgaacc tcctgccgtt ccgggtgctt gtggagccgg agcggtcggt
    15601 gaccgacacc ttccggcgga cggaccgcca gatcgggcag gcgctgcgcc accaccggta
    15661 ccgctacgag gagttccggc gcacgctcgc cgcgggcccg gagcagcacg gcgtcggacc
    15721 ggtggtcaat atcgtcaact tcgaccgcga tctgcgcttc ggaccggcca ccggcgtggt
    15781 gcgcaccctg gtcaccgggc ccatcccgga cctcggcctg tacttcgacg tgcactccga
    15841 gcacgccggc accagcgtgt gcgtggaagc gaaccccgcc aactacacgg cggaggaggc
    15901 agcccggcac gccgagggcc tcggcgggct ggtacgcgaa ctggccgggg tggatccggg
    15961 cctccccgta cgagccctgg gccggccccg gtgacgtgcg ggcggccccc ggctcactcc
    16021 cggtcccgcg cggcggcgtg cagccgcccc agcacatacc cggcctggaa ccggctcttc
    16081 gcgccgaccg ccttcatgat ttccgaggcg tggcgctgac agctgcgcac ggacatcccc
    16141 aggcgccgcg cgatcgactt gtcctccagc ccctccgaca gcatggcgac gatcgattcc
    16201 tggatctcgc cggagatccg gacggccgcg gccgagtcga agctgaccgg gaagagtgag
    16261 gcatcgcgcc acaagcagtc gaagaacacc cgtatgtagt ggacgacatg cggctcgcgc
    16321 accagcaggg ccgcctccgg gtcgtcccgc agccccagca gggccacgcg gtggtcgaag
    16381 accagcagcc ggcacaggcc gtcggtccgc gtccgcacct gcgccccgag gtgcatcacg
    16441 cgccggacat ggtcgaccgt cggctggtcg tagcgggcgg gatgctggta gagggtgcgc
    16501 atccggacgc cgcgcgtgag catctgccgg tcccgctcat ccgcctcctg gagtgcgcgg
    16561 gcggaacggg cgccacccgg ctgggcggtg agtacctcct gccgggcacc gatcgtcaac
    16621 tcgtcgatgg tctcctggac ggtccgcagg tcggtgagca gctcgatcgg ctcggcgtcc
    16681 gaacgacgcg cccgccccga ctcgtaggca gggagcagcg aggcgaacgt ctcccggagc
    16741 cgctcgatct cctcgtagcg ctcccgcaca tggcgctcca agggacgcag caaccggtct
    16801 gcggcggtcc ggggcggcac cacggtcaac cggccggcct ctccttcggc gcggcagagc
    16861 agtcgcattt ccacgagctc tttcaccgct cgttccacgt ccgcgctgtc cagtcccacg
    16921 acggtggtga gttcctcgat gccccatacg gcgcgctgtg tggcgtagcc gaatacgagc
    16981 gaagcttcct cgctgagctc aattcgtccc ggtggttctg acgtattcat catccctcag
    17041 ccccatcaga gatatccccc gatcggaagg cacgctagac atgcttgatc aacagccagt
    17101 caacatggag cagacgggcg cctcggagca gacgggcacc tccccgtgcc ggtgaagacc
    17161 gggcaccggg cggcacgcag cgcgggcggc ggactgttac gccgccaccg ggatttccgg
    17221 cagctgtggt acggggagac cgcgggcaag ttcggcgtgt ccgtcacggg tgtactgctg
    17281 ccgctggccg ccgtctccgt gctgcatgcc ggaaccttcg cggtgagcct gctcaacgtc
    17341 gcgacgtggc tgccctggct cgtcatcggg ctgcccgccg gagtctgggt ggaccggctg
    17401 cgccgccgca cggtcatgct ggtctgcgac gccgtctcgt gcgccctgtt cctgagcgtg
    17461 ccggtcgccg catggtgcgg tgtactcggc atcggtcagc tgctgctggt cgcgctgctg
    17521 gtgggctcgg cggccgtttt cttccagacc gcgtacaccg cctacctccc caccctgctc
    17581 agccccccgg accaggccga gggcaacgcg aagctgcacg gaagcgccgc cgcggcgcag
    17641 atcgccggtg tgggatccgg cggcctgatc gcacaggccg ccggtgcggt cgacggcatg
    17701 ctgaccaacg cggcgacctt cctcatctcc ttcctgtgca taggccgcat ccgccaccgc
    17761 gagccgccgg cagcgggctc ccggtcgggg cagcgcgcgc cgctgctcgg ggacttacgg
    17821 gagggggtgc ggctggttgc ccgtgatccg tacctgcgca gcctcactct cttcggaggc
    17881 gcctccaatc tcgccctggg aggctgccag gccctgctcg tcgtcttcct ggcgcgggac
    17941 atcggcctgt cctccggcgc ggtgggggcg ctggtgggcc tcggcggcgc agggggagtc
    18001 ctgggcgcgt tgctggtgcg ccggggcgcg gcccggctcg gtaccgctcg ggccctgctg
    18061 ctgttcgagc tgggcgtgcc cgccctcgcc ccgctgatgg cgctcacccg agacggcgcc
    18121 ggactggcgt tcttcgtcgt cggctacggc gctgccgcgc tcggcgtggt ggcgggaaac
    18181 atcatcaagg caggcttcat ccaagggtat tgcccctccg gtgtgctcgg ccgggtgact
    18241 gcctgctcgg cgttcgtcaa ctacggaaca ctgccgctgg gcgcgctcct cgcaggtggc
    18301 ctcggcacgt tgttgggggt gcggccgacg atgtggctgc tgaccgcggc catgccgctg
    18361 gcggcgttga tcctgttgtg gtccccgatc cgctcccgcc gcgacctgcc cgcgcgcgag
    18421 gccgacctga gctgagcgga tgacggccgt gcccctcgtc cgcgcccgtc cgcgcccgcc
    18481 cgggcccctc cgcgccgtac cgacgggcgt cggccgccct ggccccgaaa ccacgggtgt
    18541 cccttttgtc ccctctcctt tatgcgacag gcatgaacac catccccgga tgctcttggt
    18601 gcacgccttt cccgatggca acgtgaatcg cgtcggcacg gccggaaaga gcgactggca
    18661 cccgcggccg gagcaattcc gcagcgcatt ccggcagaac gtcctgcgcg cggtacgcgg
    18721 gacggaccga gccgagagcg gtgccgattc gatgtaccgc gccgattcga cgtaccgcgc
    18781 cgattcctgc cgcggaaccg tccgcacctt ccccatgacg tgaaaggaat tccatgttcc
    18841 cgctctccgg ccccgcgctg aacatgcgtc acccgtccga gatccgcaac gacaccggat
    18901 gggggtgacc tcccccgagc agcgtccgag gacatccgtc agcaacgaca tgagaggcag
    18961 cgcacaacca tgagctcttc ccggtccgcc accgcggaac cccccgcctg gaccctcgaa
    19021 cccggtaagc cggcgatggc acacgtcccc cgcttcgccg acgccgccga agcagctgag
    19081 tggctcggat cggtccacgc ggagctgcgc accgcactgc accggcacgg tgcggtgtac
    19141 ctgcggggcc tcccggtccg cgacgtcgag gacttcgcga aggtacgcga cgtcctggtg
    19201 ccccgccgca ctccctaccg tgagaaggcc accccccgca gcagctacgg gaacgacgtc
    19261 tactcctcca ccgacctccc gcccaaccag ccgatccgga tgcacaacga gaacagctac
    19321 acactgacct tccccggtct gctgctgttc tcttgcctga cggcaccgga ggagggcggc
    19381 gcgacaccgg tcgccgactg ccgcgaagtg ctccgccgga taccctccgc gctcgtcgag
    19441 cggatgcgct cggccggctg gttgctgacc cgcaactact ccgagcacat ctccctggac
    19501 tggcgcaccg cgttcgccgc cgacacccgg gagcagaccg agaagtactg cgcggacaac
    19561 ctcatctcct gcgaatggga cgcctcgggc gcactgcgta cccggcaact gcggcccggc
    19621 atcatccggc acccgcagac gggggaggag gtctggttca accacatggc tttctggaac
    19681 tcctggtcgc tggacgagga gatccgggag gcgctgctcg acgaattcgg gccggacggc
    19741 ctgcccttcg agaccggcct cggcgacggc gcgccgctga cgcgcgacga actcgacgcc
    19801 atcaacgccg catacgaggg tgcgacggtg cgcgagacct ggcagccggg cgatgtgctg
    19861 ctcgtcgaca acgtgctggc cacccatggc cgcgacccct tccgcggcga ccgccgcatc
    19921 gtcgtcgcga tgggcgaacc cgtcgccctc gcggactgcc ggcccaccgt gccgcccgcc
    19981 ccgggagagg agcgggcagc atgaccgagc tcctcgaaga ccgccggcac gccgcaccgg
    20041 accacgccgt cgatctgctg acccgtttcc agcaggccgt cgcggcgacc ccggaccgca
    20101 tcgcggtcag ccaccatggt gcgctcacct tcgccgaact cgaccggcac accgcccgtt
    20161 tggcgggagt gctggccggc cacggcgccg cgcccggccg gcggatcggc atcagcctgc
    20221 cccggggcac cgacctcgtc gtcgcgctgc tcgccgtctg gcggaccggc gccgcctacg
    20281 taccgctcga ccccgcctat ccgcaggaac gcctgcatgc gatggtgcgt gacgcgggca
    20341 tcgacgtggt gctgaccggg ggaagtgacg gcccggtgtg gccggaaggt gtccgcaccc
    20401 ttccggtcgc accccctccg gaggccccgg ccccggagca cgctccggct ccgcccgtac
    20461 cggtctccgc tcggaccccg gcgtacgtca tctacacctc cggctcgacg ggcgtaccga
    20521 agggcgtcga aaccacccgg ggcgcggtgg cggcactggt caccgggctg gaggaggcgg
    20581 gcttctacga ccatgggcac cgggtcgtcg catggaacgc cagcgtttcc ttcgacgcct
    20641 cggtccagca atgggcacgg gtgtgccggg gcgacaccgt ggtcgtcctg ggggaggcgg
    20701 agcgcaccga tccggccctg ctgggggcag tcctggacga gcacggggtg cacgacctcg
    20761 acctgacccc ctcgcactgg ccgctgctcc gcgacgacct gctcgtacgc gccgccgagg
    20821 ggcgacggct ccggctgttc atgggcggcg aggcggtacc ggagggcacc tggcgggagc
    20881 tggcggccgc acacgacgcc cggcgcctcg aagcggtcaa cctctacggc cccaccgagt
    20941 gcacggtgga cgccaccgct gcctggatcg aggacttcgc tccgcacatc ggacgccccc
    21001 tgccaggagt ccgctgccac gtcctcgacg ccgcgctgcg gccggtgccg ttcggcgagg
    21061 agggcgagct ctacctcgcc ggacggcagc tggccgtcgg ctatgtgaac cggcccgcgc
    21121 tcaccgccac gcggttcgtc gccgacccgt tcgccgccga cggcacgcgg atgtaccgca
    21181 ccggagacct ggtgcgccgg cgccccgaca actccctgga ataccgggga cgcagtgacc
    21241 gtcaggtcaa actccgcggc caccgcgtgg agttgggcga tatcgaggcc gcgctgacca
    21301 cccatccggg cgtggcggcc gccgtggtca ccctgcacag cgacacggcc gtcggcgaac
    21361 agctcgtcgc gtactacgtg gcggcgacag gtgccgcggg cgacacacct gccaccggca
    21421 cccccactcc tgacacgctc cgcgcccatc tggccgccgc tctgccgcag ttcatgcgtc
    21481 cgaccgccta cctcgcactc gacgcgatgc cgctgaccgt gaacggcaag gtcgacctca
    21541 ccgccctgcc cgcgcccgaa ccggccacgg cggacccgga cagcgctccg gagagcgagg
    21601 ccgagacgct gatagcgacc gtgtggtccg aggtgctcgg ccgtgagcac atcagggccg
    21661 acgacgactt cttcgccatg ggcggccatt cgctgatcgc cctgcgtgtc gtggcccggc
    21721 tgaagaagca gctgggggtc gtgatgtcgg cccgtgaggt ctaccagcat ccacggctca
    21781 gggacctggc gcggcacgtc gagagcctgc gcgccgaccg ctgacgggcc ggcatccgcc
    21841 tccctcgatc accgcgcacc ttctgcacca ccgtcactgc gccgcctgcg cggacaccgc
    21901 gctccgtcac cgcggagacg gagcagagac accaagagac gccgaagaga cagaagaccc
    21961 cccacacaga cagggagagg gccacgatgg ccggacctca ggacaccacc gtcatcccga
    22021 tcaaaccacc ggaccgtcac accgtgcgca cgctcctctg cctgggcttc tgcggcggcg
    22081 gcaccgggcc gtatcactcc tggagcgaca gcctgcccgc cgaggtggcc ctctccgcca
    22141 tctgttaccc cggccgggag gggcgctttc tggagccgta cgcggccgac tgggaggaac
    22201 tcgccgcgga cgccaccgcc gccgtgctct ccgcggccga cgggccatac gtcctgttcg
    22261 ggcacagcat gggcggctgg atggctttcg acgtcgcggc ccggatcgag gacgcggccg
    22321 gcccggcccc ggaggcactg gtcgtctcct cgtgcaacgc gccggaccgc ggtctgactc
    22381 cacgggacat gttccccgcg cgccaggaca ccgacgccga gttgctggac tggatgcgca
    22441 ccaacggcct gatgcccgaa cacgtcctgg cggacccggg actccaggag atggccgtgg
    22501 agctgatgcg tgcggacatc cgggtccgtg acacctttcg ctgccggccg gggaccacgg
    22561 tgggcgtccc cgtccagatg ctctccgcga cggatgacga tgtcatcgag ccggacgccg
    22621 gaaaccagtg gcgccgggtc gcccgcggcg cctaccgcca cgatgtgctg cccggcgggc
    22681 acttctacac cccggagatc tggcggcagc tgccggccca catcgcaccg ctcaccacac
    22741 cggcatccca cgccgcggtc tgagcccgca gaacgggaac gttccgcccc acaccgctcc
    22801 ctgccacctg aaaggacatc ccccgtgacg catacgcacc ccttcgaaga cgtcgacgcc
    22861 acctatctcg tcctggtcaa ccagcacaac cagcactccc tctggccgtc gcacctggca
    22921 cctccgcagg gctggacggt gacccggggc gccgacggat atcaggcctg cctcgaccac
    22981 atcgaggagc actggcgcga tctgtcgccg cagcccgcca ccggcaactg acccatctcc
    23041 gtctccaagg gaggagcacc atgacgcaag cgcagagccc cgcggtcggg gagcaggccg
    23101 atgccacagc cccgtccggg gacggccccg gccgtgccgg gagggggcgt ggtccgcggt
    23161 cagtgcggga ggaggtgttg tgccggctgt tcgcccaggt gttgggtgtg ccgacggtcg
    23221 gggtggcgga caacttcttc gccctgggcg gccattcgct gagggctgcc cagctcctga
    23281 gccggatccg ttcggtgctg ggcgtggagc tgggcgtccg cgaactgttc ggttcgccga
    23341 ccgtggcggg gctggcggat ctgctggccg agggtgccgt ggcccggccg gcggtgacgg
    23401 cgcgggcgcg gcctgcggtg gtgccgctgt cgttcgcgca gcagcggctg tggttcctgg
    23461 accgtctgga gcagagtccg acctataacg cgccgttcgc cttccgggtg cggggcccgg
    23521 tggatgcgga cgccctccag tccgccgtca atgatgtcgt cgggcgacat gaggcgctgc
    23581 gcacggtctt cccggtccgc gacgacgagc ccttccagga catcctggca cccgagcacg
    23641 cgacggtgaa ggtgacggtg gtgccgtgtg ccgccgagga gctgaactcc ctctttcatg
    23701 acgtggcgtt cgcccccttc gacctggcgg tcgaacttcc cttacgtgtc tcgctgttca
    23761 ccaccgcccc cgatgaacac gtactgctgc tgacgttgca tcacatcgcc agcgacggct
    23821 ggtcggaagc tccgttgctg cgcgatctgt ccacggccta tcgcgcccgc ctcaccgaca
    23881 gtgttcctgt gtgggaggca ctcccggtcc agtacgcgga ttacacgctg tggcagcgtg
    23941 agcttctcgc ggaggtgggt gggcagcagt cggacttctg ggtggaggcg ctggagggtc
    24001 ttccgcagga gctggcgctt cccaccgacc ggccgcgccc gtcccggccc acccattccg
    24061 gtggtcttgt ccatttccgg ctgcccgccg acttgcatgg gcgtcttgag tcgttggcgc
    24121 gtgagcaggg tgcgacgttg ttcatggtgc ttcaggcggg tctggcggcg ctgctgacgc
    24181 ggttgggggc cgggacggac atcccgttgg gtaccgcgac ggcgggacgg acggatcagg
    24241 cgttggacga catcgtcggg ttcttcgtca atacgctggt gttgcggacg gacacggcgg
    24301 gcgatccgtc gttcggcgag ttgctcgccc ggacacggga gggcgatctg gcggcgttcg
    24361 cccaccagga tctgcctttc gagcagctgg tggagaggct gaacccggac cggagcacct
    24421 cgcgccatcc gctcttccag accatgctcg tcctccagaa caacgccgaa ggcaccctcg
    24481 atctccccgg caccaccctc acaccccaac ccctcgacac cgcaccctcc aaattcgacc
    24541 tcggttggag cttcaccgaa gagcgggacg ccgacgaacg ccccctgggc atgtccggca
    24601 tcctgcagta cgccaccgat ctgttcgacc gcaccaccgc ggacaccctg accggcctcc
    24661 tcgtccgcgc tctcgacgcc gccgcggacg caccggacac cgccatcggt tcgctggaga
    24721 tcttcgcgtc gcggacagcg gagcgggcat tcctggaccg cacggacgag catcggctcc
    24781 ccgcccgtcg cgcgtccggc cctggcggtg ccgcagatgc cggtccgacc tccggggacg
    24841 gccccgaccg tggcgggagg ggcgagcgtg gtccgcggtc tgcgcgggag gaggtgctgt
    24901 gtcagctgtt cgcccaggtg ttgggtgtgc cgacggtcgg ggtggcggac aacttcttcg
    24961 ccctgggcgg tcactcgctg ctggccactc ggctgctgag ccggatccgt tcggtgctgg
    25021 gcgtggagct gggcgtcagg gagttcttcg gatccccgac ggccgcgggg ctggcggatc
    25081 tgctggccga gggtgccgtg gcccggccgg cggtgacggc gcgggcgcgg cctgcggtgg
    25141 tgccgttgtc gttcgcgcag cagcggctgt ggttcctgga ccgtctggag cagagtccga
    25201 cctataacgc gccgttcgcc ttccgggtgc ggggcccggt ggatgcggac gccctccagt
    25261 ccgccgtgaa cgatgtggtc gggcgccatg aggcgctgcg cacggtcttc cccgcccacg
    25321 agggcgagcc gcagcagcag ctgctcgccc ccgacgaggc cgccgtcgag gtcaccgtgg
    25381 tgccgtgccc cgccgacgag atctccgccc gcttccacgc cgcggccttc acgcccttcg
    25441 acctcgccga ggaactgccc ctgcgggtca cgctgttcac cgtcggcgcc gaagaccacc
    25501 tgcttctgct gacgctgcat cacatcgcca gcgacggctg gtcgctggtg cccctgctac
    25561 gcgatctgtc catggcctat cgcgcccgcc tcaccggcag tgttcctgtg tgggaggcgc
    25621 tggcggtcca gtacgcggat tacgcgctgt ggcagcgtga gcttctggcg gaggtgggtg
    25681 ggcagcagtc ggacttctgg gtggaggcgc tggagggtct tccgcaggag ctggcgcttc
    25741 ccaccgaccg gccgcgtccg cctcagccca cccattccgg tggtctcgtt catttccggc
    25801 tgccggccga cttgcatggg cgtcttgagt tgttggcgcg tgagcagggt gcgacgttgt
    25861 tcatggtgct tcaggcgggt ctggcggcgt tgctgacgcg gttgggggcc gggacggaca
    25921 tcccgttggg taccgcgacg gcgggacgga cggatcaggc gttggacgac attgtcgggt
    25981 tcttcgtcaa tacgctggtg ttgcggacgg acacgtcggg cgatccgtcg ttcggcgagt
    26041 tgctcgcccg gacacgggag ggggatctgg cggcgttcgc ccaccaggat ctgcctttcg
    26101 agcagctggt ggagaggctg aacccggacc ggagcacctc gcgccatccg ctcttccaga
    26161 ccatgctcgt cctccagaac aacgccgaag gcaccctcga tctccccggc accaccctca
    26221 caccccaacc cctcgacacc gcccccacca aattcgacct cgacttcacc ttcaccgaac
    26281 ggcacggcgc cgacggcagc cccgacggcg tcgacggcct gttgcactac tcggccgacc
    26341 tgttcgaacg tgccaccgcc gaggccctgc cccagcgcct gctgagcctc ctcaccaccg
    26401 ccggcgccgc cccggaaact cccatcggag cgatggaact gctctccccg caggagcgcg
    26461 tccgcatcct ctccgggtgg aacgacaccg cccttccgct gccggacgac cggctggtgc
    26521 acgagatctt cgaggagcac gtacggaaca gcccggatgc caccgcggtg gtcgacgccg
    26581 acggcacgct gaccttccgt gagctgaacg cccgcgcgaa ccggctggcc tggctgttga
    26641 tcagccaggg catccggccg gaacagcggg tggccacctt gctcccacgg gccggtgagc
    26701 acatcgtcgc gctgctggcc gcgctcaagg cgggctgctg ctacgtgccg atggacccgg
    26761 aggaccccga ggaccggatc gccctgatgc tggcggacgc cgcgccctcc ttcctgctga
    26821 ccgaccggga gaacctggcc cggctccgtc cgggggccga tccctcgatc caggtgctgg
    26881 tcctcgacga ccccgccgtg cgtcagtccc tcagccggta cgcgccggtc gatccgcact
    26941 ctgcggaccg gcccgtaccg ctgcgcccgg accatctcgc ctacgtcatc tacacctcgg
    27001 gttcgacggg ccggccgaag ggggtggccg tggagcaccg caatctcagc aacctgttcc
    27061 acgcccactt cgcggtgttc gcgcctcagg tggcggccgc cggggaccac cggttccgtg
    27121 ccctggtgac cggaccgctg accttcgact cctcctggga accggtcctg tggctgctgg
    27181 gcggccatga actgcacctc gtgcacgacg aggtccgccg cgacccggag gcgatggccg
    27241 agtacatcgg cgccgcgggc atcgactaca tggagatctc gccgacgtac tgccggcagc
    27301 tgatgacggc gggcatgctg tccgcagggc agccctcgca accgcgcatc gtcgagctcg
    27361 gcggcgaggc cgtcgaccag gcgctgtgga gcgaactccg cgccatttcc gggaccgagg
    27421 gcttcaactc ctacggcccg acggagtgca ccgtgtacgt gtcgtacggc gcggcagcgg
    27481 aacacgagcg cccgctgatc ggccggccga tcagcaacaa ccggatgtac gtcctcgacg
    27541 cgggcctgcg tcccctgccc gccggggtgg tcggcgaact gtatctggcc ggagcgggga
    27601 cggcccgcgg ctacctgggc cggccggggc tgacggcaca gcggttcgtg gcctgcccat
    27661 tcggagagcc gggggagcgc atgtaccgga ccggggacct ggcgcgctgg agcgccgacg
    27721 gtgtcctgga atacatgggc cgcaccgacg aacaggtgaa ggtccgcggc ttccggatcg
    27781 aacccggcga ggtggagtcg gtgctcgccg gacacgacgc ggtccgccag gtgaccgtga
    27841 tcgtccggga ggacaggccg ggggagcgca agctggtcgc ctatgtggtt ccgacggagc
    27901 agggccgggc ggatgcccgc gagctgcgcc gtctcgccac ggcgtcactg ccccgccaca
    27961 tggtgccgtc gtcgttcgtg ttcctggacg ccctgccgct gacctcgcgc ggaaagctcg
    28021 accggcggat gctgccggca ccgggtgacg ggacggtgga gcgccgccga ggcccgcgaa
    28081 cggtgcgcga ggagctgttg tgcgggctgt tcgccgaggt cctcggggtg cccgaagtgg
    28141 gcatcgacga cgacttcttc gccctgggcg gccactcgat gctcgccacc cggctgatcg
    28201 ccaggacgcg ttcggtgctc ggcgccgagc tgggcatcag gaccctgttc gatgccccca
    28261 ccgtcgccgg actcgccgac cggctctcgc aggacacacc cgacgactcc ctcgcggtcc
    28321 tgctcccgct gcgctccgta cgccgggcgg ccacgccgtc ccgcacacgg ggcgccacac
    28381 cccccgagcc gctcttctgc gtccacccgg cggccggaac cagctgggtg tactccgggc
    28441 tgctccgcca cctggcgctc gaccagcccg tgtacggcct tcaggcacac gggctcaccg
    28501 agcccgatgc ggctccggaa agcatgacgg agatggtgga ggcctacctc gcgcagatca
    28561 ggtcggtgca gccggacggc ccctactcac tcctcggctg gtccttcggc ggggtggtgg
    28621 cccacgagat ggcagtacgg ctccaggagg ccggacagaa ggtgaactcg cttgtgctga
    28681 tggacagtta cccgtcgcgc gtgaccgccg acggccacga cacaggaagg acggaaaaga
    28741 gcggatcagg gacggaccgg ggcgacgcac cggatgcgga agaactgcgg caggccctgt
    28801 tcgactccct cgggcaccag gcggacgcca cggacggccc gctcgccctg ctcggggaac
    28861 agggcctggc ggccatggtc cgggtattcg cccgcaacag tcgcctccag agcggattcg
    28921 tcccgcgctc gttccggggt gatgtgctgt tcttcgaggc caccgagggc tgggttccgg
    28981 gcatgcagcg cccgcaggcc tggcggcccc atgtgacggg ccggctcgcc atcactcccg
    29041 tacgtggcgc gcacggcgaa ctgacccgcc cggagcagct cgcgcagatc ggtccggtgc
    29101 tggccgactg gtgtgccgaa tacaggaagt gacgccacag tgcagcggat cgcgtcccgc
    29161 ccggaccccc agcggtgtcc gggcgggacg tggtcactga ccgacggcag ccccggaacc
    29221 cgtatggagc ccgagaaccc ggtacagttc cgcggctttc tccaagtggc ccgccgcctc
    29281 cccgtccacg tactcggccc gcactgcctg aagggccctg ccgagagcct ggtggctgcg
    29341 cgccatcagc aggtgctcct gggtgagttg agctccttga agggcctgcc gcgcatgatc
    29401 gacggcggca tgggcgtccc cggtcagcag gagtgcctcg gcgagccggt acaggcactc
    29461 ggtctcgttt cgggcatgac cggtggtccg ggcacgcggc aacacctggc ggtagagcgc
    29521 ggccgcctcc gcgggacgcc cgccgtacaa cagggtgtcc gcctccgtcg tcatcacccg
    29581 gatcagccac ttcacgtcat tgccgcaggt cagcaggtcg gccagctccc ggcactgctc
    29641 acggatccgg gccaggtccc ccctgctgcc gggatcctgg gcccggatct ggagcaggag
    29701 ggtgcgccgc cgtgtgacca gcccctgatc gccggtgatc atcgccatct ccaccgaccg
    29761 ctccgcatgg gcgcgggcag agctgaagtc ggcgcacatg gcgtcgaggt gggccagcat
    29821 cgcatgggtg aagagaactg ccaggaaggg ccggaggcca tcggcgggtg cgggagactc
    29881 accgaagatc tccagtgcct tcagcagatg cgcccgtgag cggtcgaggc agtccagcga
    29941 ggagtgcttc ttgaggatca ccccggccgc gtaatgagcc gtgcccacca cgtcctcgtc
    30001 gcagtacgcc accgcggacc gcaccagagc ggtggccgcc ggcgccagca tgccgagggg
    30061 cacgctctcc tcgaagcagg gagccagcat cagcccgtcg acggcgagtg ccaccgcctc
    30121 cgcgtctccg ctgtcggccg cctgctccgc cacggcggcc acggtgggca gcgctctccg
    30181 catccactgc accgcctcct ggccggtccc cacgtcctcg cccgccgacc gccgcggtcg
    30241 cagctcagag gtcagccgaa cgcccagcgg ctgggtcgcc aggaccgctc cggcgacact
    30301 ggcgcacatg aagtcggccg cgcggcggac gacttggcgg agttcctcgt cggtcagctc
    30361 cactcgagcc gtcgctcgcg cataggcccc gaccagatcg tggtagcggt agcggcccgg
    30421 tgcgcgggtc tccaggagta ccgcgtcgac cagggcctcc aggacgtcct ccacctcccg
    30481 ctccggaagt tcgagaaccg cggcggcgcc cttcacaccg aactcgacgc agtgcgggag
    30541 ggacaattcc agaaacgccc gggcccgctg cggggagagc tgcgcgtacg actgctcgaa
    30601 caccgcctcg accgtcagct caccgacccg cagttccccg agcagcctgg cctcgtcgga
    30661 catccgggac agcagcgtgg cgaccggcca ggccggccgg agcgcgaggc gagcgccgat
    30721 cgcccgcagc gccaacggca gatggccgct ggcggcggcg agcgccgcga cggcgtccgg
    30781 ctcctcctcg atccgccgga taccggcgac cttgccgatc agctccacgg aatcgtgggg
    30841 gtcgaggccc ttcagcgaca ccttgacggc ggccggcagc gccgccagcg cacgggcggt
    30901 gaccaggacc gcgcactggt cggcgccggg cagcaacggc tcgacctggg cgacggtggc
    30961 ggcattgtcc agcaccacca gcacggcgcg gtccgacagc agggtgcgga acagtgccgc
    31021 gcggtcgctc accgaagccg gcaggcgctc gtgcggcacg cccagtgagg tcaggaaacc
    31081 ggccagaacg tcggccgggt caccaggagc gccgcacggt gtgcgcagtt cggcgtacaa
    31141 ctggccgtcg gggaaggagc ccatgaccgc atgcccggtg cgcagggcca gcgcggtctt
    31201 gcctacgccg cccatccctg tgatgaccgc gacggggtgc gaggcgtgcc cgctgagcgc
    31261 ggcgaccagg gtgcagacct cgtcgtgccg accggtgaag tcgcacggta cggccggcaa
    31321 ctgggcgggc gccctcggcg cggggacggc cgaccacacc tgcacctcgg ccgggacggc
    31381 agcggtcctc gccgtagcag gaaccgccag cagagtccgg tcacccgcca gcaccgcggc
    31441 gtgcagcccg tcgaggacgg ggcccgtatc gatgcccatc tcgtccgcga gtacctggcg
    31501 ggcgtgatcg taggccagca gcgcatcggc gctccgctcc gaccggtaca gggccagcat
    31561 cagcgcaccg tgcagccgct cccggtacgg ataggcctcc agagcgcaca ggatctccgg
    31621 caccacctcc tcatgccggc cgcacgccag cgacagctcc aggtggtgct ccgtcgccga
    31681 ggcccgctgt tcggccagcg cccgtcgctg ttcctgcgcg tagggcccgg ggagccctgc
    31741 cagcgccggg ccctgccaca taccgagcgc ccccttcagg acggatgcgg catacgcggg
    31801 atcgccctgc gcggccgcac gccgggcccg cagtgtgagc tggccgaaca gcagagcgtc
    31861 gacacgctcg gccggcagtc gcaggacata gccgtccgcc atggtcccga tgaccgtggc
    31921 cccaccgtct cgaccggatg cggcgccacc ctccctgccc gcggtgtgcg cgcggtcgag
    31981 gtatgtccgc agccgatgga cgtagttgac gatcactcgg cgggcggagg cgggcggatc
    32041 gtcgtggtac agaccgtcca ccagttgatc gatcgtcacc agggtccccg cacggagtgc
    32101 cagagccgcc agtacggcct gtggccccgg cgctccgggc cgcccggctg ttccgtcagc
    32161 cgaaacgtat tcgacgggac cgagcagccg gaggtgggcc actccgtgta gtgcggataa
    32221 gtgtgacatt gctcctgtat accaactaaa ctacacagaa ccagagttga cgcgtcggcg
    32281 ggcgcgagta gggccccagt gcggcggtgg tgccaggggc cggacacacc ctggcgacgg
    32341 cgacgccaga aggactacag acggtcttac gcgtgctcgg ccagggcact catgagcccc
    32401 aggcttccca gcgagattct cggcagcgtg ccccacagtt gcctaagttg ctaacggcag
    32461 gccttgttag ccggctgcat ttttgcgctg gttggcatgg aagcgcgcct tcttctgacg
    32521 attcccgcat gtgttcatgt cgcaccatct gcgggtgcga ctctggctgg tgtcgaagaa
    32581 ggcggcttgg caggttggcg atgcgcacaa ggccagtttt ccgtctcgtt cgcccgcgat
    32641 gatgctgatc gcgtcggcgg cgatcacgcc tagggcatct tctacgcagg aagccgagct
    32701 gagtcgccat tgccgattgc tctcgggcgt caggatggcc gcggcccgac cctgagtgct
    32761 gcagtcattg atgacgtgga cagcagacgc ggggagagga tcccggatcg ccgccgctgt
    32821 caaggcggcg tgaatcgatt ccctcagttc ccgcgcgagt tcgagctggg cggtggtgca
    32881 ggactccacg gcgaggccgt tcaccgccag ccagtcgacg agtcggtgcg gcgtggggat
    32941 gcgttccaca gcgtcgccac gccgctccgt cagggtcgcc gtgaagctgg tcgccagcac
    33001 cttaccgaga cggaagtcag ggaaccgagc atgcatggaa ccaccttagc gggttgcgcg
    33061 ccggcatcga ggcacgctag aaccgtctta ggtggttcat gacaggtcca agccggttcc
    33121 acgatgacca ggaggtctca tgcccagcga cgtgcaagca tttgaagccc acgcaactga
    33181 cgccgacctc gacgatctgc gcgcgcgatt ggccgcggcg cggctaccgg aggccgagac
    33241 ggtctatcgc gccgcgcccg gccctcgccg ctggggacag ggcgttcctc tcgccgacct
    33301 cgtcgatgtc gtgcactact ggcgcaccgg gtacaactgg cgctcgttcg aggagcgcct
    33361 gaaccgcatc ggccagttcc gcacgaccat tgatgatctg ggcatccact tcctgcaccg
    33421 ccgatccgcg cgcgcagatg ccacacctct gatcgtgacg cacggctggc caggcagcat
    33481 tgccgagttc atcgatgtgg tggacgagct ggccgatccg aaagacgcgg acgcgccggc
    33541 gttccacgta gtagtcccgt cgttgccggg ctttggctac agcgacaagc cggccaccac
    33601 cgggtgggga accgaaaaga tcgcggccgc atgggtggaa ctgatgggaa ggcttggcta
    33661 cagcaagttc gtagcccacg gcggcgactg gggagggaac atcaccacgg ttctgggtgg
    33721 caggttcccg gcgcacgttc tcggcatcca caccacgttc gcggaggcac cgcccgggtt
    33781 gacaacggac gggctgacgg cggccgagcg taaatggacc gaggacaccc gcgatttctg
    33841 gcgccaccgc gcggcgtatg cgaagcagca ggcgacccga ccgcagacca tcggctactc
    33901 gctcgtcgac tcaccggtcg ggcttctcgc ctggatcctt gacaagttcg ctgagtggac
    33961 agataccgaa gacagcccgt tcgaggcgat ttccagagac cgggttcttg acgacatcac
    34021 cctgtattgg ctcacacgga ccggcgcatc gtcggcccgc atctactacg aaagccacaa
    34081 ctcgctcgac cccgaacttc gggtggacgt cccgtcagcg atcactatgt atccccgcga
    34141 catcgagaag tgtccgcgcg gctgggcaca ggagcggtac cgacagatcg tccgatggag
    34201 gtcgcccgaa accggggggc atttcccgtc gctggaggtt cccgagtatt tcgtcaagga
    34261 tctgcaagaa ggcctcgcgg cagtactggc cgctcgtcgg tgaacgcggc tgggtctgag
    34321 cccgaatcca ccggctgatg atctgatgcc gtgagctgac ggtgagtgag gtaacccgac
    34381 gaggccgccg gttccggggg cagggatcag ccgccggccg gggccggacc cttgggtgtt
    34441 gtgggtttgc gcttcagttt caccgtcgtg cgtgggtgtc atgtgcacga caccccctcc
    34501 aggcatcgaa ttattcggca gctcattcga atctcaccgg gtgggtgggg ccagggatgt
    34561 tacccaggcc gctatcgaat tctgggggtg atagccgcga acacttcgcc tgcgacgaac
    34621 acggccgccc cctggcttcc tggtcaccgt cggcacccgc aacgattgca tccaggtcga
    34681 agccgttatc agtcacatcc atgtgctgcg gtcgggcccg ggccgccaac gaccccgacg
    34741 ctctttgtgc caccaagtcg tctgtaaggc cgtcggcgcg gaagttatga ccgcggtcgc
    34801 gggagaagga gggcgaggtg ctgctggcct gataccgacg ccatggccaa tggtcattgt
    34861 tccagcgggt gttgacgatg actagcttgt actccgtcct cccaaagggg tggagtgcgg
    34921 acggatgcac atcggggaag cgcacactcg gattcctgag tgctgttccg tgccggatgc
    34981 ggtgttgttc cgggggaaac ggcgcctgag ggcgggggag cgtgtgaccg agaagtcccg
    35041 gcgggcgtcc ggtcgtaggt ctatggccct tcagcgcacc ggagcggcca cgcctggact
    35101 gagcggtcac cacaagccga ggaggccaga cagtggctga gcgtatgaag ttgttgttga
    35161 caggtcgcgg ccgttatccg tttgctgatc agttggtcaa ccgcaatccg gataacctcg
    35221 atcaggacca gccgaccggg ggaatcccgc tggcgcgtca tcatgtgatt ccttttgaaa
    35281 cgctcgtgaa gagttggaac gtgttgatcg agaacgcgta caacgtgaag gggtccgaac
    35341 tcaggaacgc gctggtggac ttcgccgaca cctgggccac gaagctcgag agcctggact
    35401 acaaggagca ggagaagctc aacttcccgc gtatcaggga gttcgtgaag gacctcaaag
    35461 acccggagtc cgtctacgac cccgacggcg gagtcagtcc ggacgggttg gacgacatcc
    35521 acagcgttct gacctggctg ccgggaaatc ttttcgtggg cccggacaac aagaaccgga
    35581 ccgatgatcc gggcccgaaa gttgaagcag gcagcgcgag gatcatcggg tcgggcatcc
    35641 tcaccaagcg gactgcgacc ttcgagagtc tgtcccggta cagcaagaag cctatgggcg
    35701 cagggatgac gcgtgacggc ctgacgggcg tccagggcct cattgaggct ttcaccccgg
    35761 accggttgtg gccgctgaag aatgcggact gggagaaaaa gggcgccaag tatggcatcc
    35821 ggcccgtggg tgccgcctcc ggtgcgctgg tgggaccgtc ctcctcgccg gcacggggca
    35881 tgccgcacgg cgtcgctttc atcgtcatcg gcggtgtcag gctggagttg accacttggt
    35941 cagacgacgg aggctacgtg cttcgcgggg tgagtgccgc gaacatccgg atggctgacc
    36001 tcctcgactg gctcggcgaa acctgggaca tcgccgagga gatcccagag agcttgcgga
    36061 gtttccgcct gcagtacctg accatcgagg tgctgacggt cccgggtgtc ttggaggagt
    36121 gggaggtcac cgcggcgacg gaagtcacct tcgccggcgt gacgatggac ctgctcgtct
    36181 gcttccgcca ctcgacaccg gcaggtgggg cctcggcgtt ctcgctgtcc gcggacgccg
    36241 gtttcaccgc ttccgtcaac ggcgaagacc tccggctgtg gttcagcgga gcgatcgccc
    36301 ggacggtctc gggggcctgg gaactgagcg cgtccctgga ggagcagagc ggggtcctga
    36361 gcctggctca cctggccgcc gccttcggcg tcgacgtccc ggcggacctg gaacctctcg
    36421 tcccttcctt cagctcggcg tcgttcacct accgcctccc ggccggaagt tccgcggcag
    36481 ggtcactggt gctgtcggcg gtcgtcggcc gggtgggggt ggtggtggcg tcggagcctg
    36541 aaggcgccgg atcgacggtt gcccggttgg tggcgatccg aggagatgtg acggcccggc
    36601 tgtccgagct gccgctggtc ggcgcgtcca tcccctggga acgggatgtg ctcttcaccg
    36661 gtgtccattt tgcctactcc tcgggacgct ggtcgcggga gcaggtggag cggctcaaca
    36721 cgatcgtcga cggactcgac ggcgggccgg agcagcggct accgcgtctg ctgggccagg
    36781 cgctgccgcc tggtgcactg gcctgggtga acgtgacggt gggcggcaag cctcgcgggc
    36841 cgctgattct gaagctgccc gacggtggca gggcggcggc accgggccgc ggtgagggag
    36901 cgtggggcgg cgccggatcg gcgcagtccc tggtgctggg ccgcgaacgt gccgaggacg
    36961 gcgaggacac ggccaagggt ctggagctgg gcgggttcgc gatgggcccg gtccgcttcc
    37021 accacgccgg cctcggctac gcgcagggac gtctgttcgt cagcctggat gccacgatgg
    37081 cggtcgggcc gctgaccgtg gagctgcagg gccttggcct gggcgtggac aaggactgga
    37141 acatcgcgcc ggttttacgc ggtgccggtg tcgcgctgga gcgcccgggg ccgcccaagg
    37201 tggtcatcgc cggggcgttc acccggctcg acctggggcc ggagttcgag ctggcgttcg
    37261 ctgccgcggg ccggatcgag atccaggatc tcgtcagcct tcaactgatg ggcagttggg
    37321 cacgcaacag ggcgggatgg gattcggtct tcgcctacgc cgaactcgtg gcgggcaaga
    37381 accgggtcaa cggcctgttc accgtgggcc cggtcacctt caccgggatc gccctcggct
    37441 tcggcatcaa cagcaccgta cgcatcccca cggccagtga gatcagccgc ttcccgctgg
    37501 tcaaccggct gggcgcgcgc ccgtccacgc ccggcggcga ggtcgagaag ctcactccgt
    37561 cccaggcact gaacgaactg gtcggcccgg gcggctgggt gaccccggcc cacggccaat
    37621 actgggtggc gggcggtatg gagttcaccg tctaccgctt catccaggcc aaggcgatcg
    37681 ccctggtgga gtggggtgag gccggctgga aggccatgct ggcaggccgt accactctgt
    37741 cactgccgcc caccaccgtc cccgccgaga gtgcggcgtc agtgccgggc gcggggatca
    37801 acctgtccct gggcggcccg ctcggcaagg tgatcgtcga cttcgtcttc gcctacgact
    37861 ccgcgctcgg ccgcttctcc atggatacgg tgatcgcgga cggctcgtac atcctggacc
    37921 cgcaggcaag gctcaccggc gggatctcct tctacgtgtg gggcaaggcg ctgcccgccc
    37981 agggcgtgcg caagggcttc gtgctcaccg ccggcggcta ccacccccag ttccgggccc
    38041 ccgcctactt ccccaaaccg ccccggatcg gctgggtatg ggagcgcggc ccggtgtcca
    38101 tccgggccca ggcgtacgcg gcgctgaccg acggggcgtt catggtgggc ggtgagctgg
    38161 ccgccgtcta cgacagcggg cacggcatca acctgcgggc ctggttcacc gcctacgtgc
    38221 acgcgctggt gcagtggaag ccgttctacg ccgacctggc gctgggtctg agcatcggcg
    38281 tcgccgccac cgtcaaggtg ctgttcgtgc gggtgcgtat ctccctggag gtcggggtcg
    38341 acctccagct gtggctgccg ccggtcggcg gcagggcccg ggtgaaggtc tggttcatca
    38401 ccttcaccct cggcttcggc tccgaccgca agggcgcgcc ccctgcggac tggcaggact
    38461 tccacgtcca gctgcccgcg ccctcccgca ccgccctgaa gcagggcagt gagctgccgg
    38521 acgtcagcca ggacgagtcc gcggcccgtg cggcggccga cgagccgcag ctggtacgta
    38581 tcgaggggtt caccgcggcc gtcgaatccg cgctgcccgc ctcgaagatc accctcaacg
    38641 gaaagctctt cgcgggcagc gacagcgccc ggatcgacat ccgcccgatg aggctgaccg
    38701 gagtcgtttc cgagcagatc gtccagatcc tggaccagcg cggcaaccgg tacgactggg
    38761 aaaaggcccg ctggacggtg accgccaccc gcgagagcct gccgcaggcg ctgtggggca
    38821 agccgctcgc ccacccgaac caggcgctca accagcccgg cctggtcgac gactgtctga
    38881 ccgggctgac catccaggtg cccgaaccga cccgtcggcg cggcgtcgga ccggtacccg
    38941 tcgaggccct ggacgtcgac ggcctgccgc ccggccggat gccgctgcgt gacgagacgg
    39001 tggccggccg ctccccggtc accgaccccc acagcatcgc gctgatcggc gacacgctcg
    39061 ccgaggccgg gaccgcggcc cggcgcaccc gggcgcacga cgcgctcgcc gcactcggcc
    39121 tggcccccgg cagcgacggc ccgctgaccg gcaccgcccg gctgaccggc acctccctga
    39181 ccgacgcccc gctcctgacc gaagccgcga ggtgaccgcc gtgcctgccc gccccgacct
    39241 ggacgtcacg ttctacgacc acctcgcacc agcgaccacc gccggcatct acaccatcac
    39301 ggtggaacac tgcctgacca aggacggccg acggctggac gccacggccg aactgcccaa
    39361 ggccgaggac cgctacgaga tccgcgcggc tcggttccac ctcgacccca gctccgtcca
    39421 cgccacctac cccgcagccg gagcagcggg ccgttacccc cacgtcctgc cgcacatcac
    39481 gctccaccgg gcgatccttc cctgggagcg ccaactgctg ggacgggcgg tccccgcgcc
    39541 ctggctggcg ctgctggtcc tcgccgaggg cgagaccgtg gacgaccccg atgccaaggg
    39601 cgagttcacc acccgcacca tcggccgtct ccgcaacccc gccgaagccg gcacggccgg
    39661 gccggaactg tccggagaca tcaacgacga cctgccctgc cgcacgatcg atgtgccggt
    39721 ggacgtcttc cacgcggtcg tcccgcgcga ggacgagctc tctcacctca cgcacatgcg
    39781 cgaggtgcgc accgcacccc aactccgcga caacggcgag gtgttgtccg aaggcgagta
    39841 cgccgtcgtc gccgccaacc gcttcccccg cacccccggc acctacgccg tacacctggt
    39901 ctccctggaa ggccacctgg gccgcctcgc ctccggcgcc cttgccgaca gcgagcgagt
    39961 gcggctgtgc agcctgtggt cctggtcgtt caccaacgcc cccgacggca ccctcgaccc
    40021 cggcacgctg ctgcgcggcc tcgtcgcccc cggcgccgag gacccggaga acctcgcgct
    40081 gcgccacgct cccgcggccg gctcggcgtc cacagccgag gagcggtacg cacgcacccg
    40141 gctgcaccac ggctacagcg ccgtcgccca ccgcaccctg gcgggggagg acacctacgc
    40201 gtggtaccgg ggcccgctca ccccgctcac cgctccggac ctgccaggtg aagccttcca
    40261 gggaccgcac accaccgccg accacgccct gatctatgac cgcgagtacg gcgtcttcga
    40321 cgtcagctat gcggcggcgt ggacgctcgg ccgcaccatc gcgctcgccg atcccgacta
    40381 cagcgccgag gccgtcgagg cgcggcgcgc actgtccgac cgcgccgcca ccctggccgc
    40441 gctcggcagt gacccccacc gcgcccggca cgaccccgac gccccgcccg ccgccacggc
    40501 gctggacgaa ctcgcctcgg ccggcttcgg gcgccgcctg gtccaggccc tgcgagccga
    40561 cctgcacccc gaaccggctc ccgcaccggc tgcgcgcacc gcccgtgccg aaccggccac
    40621 gctgctcgcc gacccccgcg cccggcagtc gctcagcgcg gtgatcaacg cccgcacacc
    40681 caccatgtcc gagtggctgg accgcctcgc cctgctgcgc agtgtgcctt tccaccacct
    40741 ggtacccgac ccccggatgc tgccgcccga gagcctgcgg gccttccgcg tcgacggggc
    40801 ctggatccag gccctggtgg ccggcgcgac ggacgtcggc gtccacacct ccgtcgaccg
    40861 tgacctcgat ccgctgctgc gcgaacggct ggcccgagct caccgccgcc cgatcccggc
    40921 ggccgggctg ctgatcaact ccgagctggt ccgcgcctgg cccgtcttcg acctgttcgc
    40981 cacccggggc ggcgaacagg tcggcgagct gcgccgcgac cacctggcgc ccgacatcct
    41041 gctggtgttg tgggacgccg tcccggacag cgtcaccctt cgcgagccgg ggcagggcat
    41101 ccacttcggc atcaactccg aacggcgcgt cagcctgcgt tacttgtccg gtgacgacgt
    41161 cggctacccg accggcaccg agttccccga cccggtgagc ggacgcaccg tcttcgacca
    41221 cctgcgcccc ggccgttccg gtggcctgcc ggacgtcctc gacctccatg gcgcggacgg
    41281 cttcgtcgcg gcgctgtccg aagcctgcgg cgcggacgac gagctgtcgc ccggacagtt
    41341 cgccctggaa ctcgtcaacg cccccctgga gcagctcctg ctgcccgcgc ccaccgccga
    41401 ggagaccgcg tgagcgatac cgacctgatc gtgcccgtcc aggtccacgc cctgctggcc
    41461 aaccggaagg tgcgcaccct gcacccgttc caccgctacc agccgagctt cgaccgcatg
    41521 ctcggcacct atccggacac cgagggccgg ggcgccgccg aaccggaggc cttcagcggg
    41581 gccaaagagg tcggcgggga cgagaccttc gagggcgtgc acgtccagtg ggagctgccg
    41641 gaagcgctca ccgacggcct catggccgag gacgacggcc ggacgcactt ccccttggtg
    41701 cccaaccgct ggctggtcgt ccgctactcc tgggtgcgcg gtgagcgcaa ggccgttggc
    41761 tgggtcgtgc acagcgacta cctgtactcc gatgacgacg gcgcgctgtg gaacggctac
    41821 gacaccatca acagcttcgt caacccgcgc aagaaggacg cccccgaggt cgactggctc
    41881 ggccgtgccc accggctcgc cgacggcccc tggcaggaac cgccggggga ccggaagctg
    41941 ttcctgaccg ccgcgggcgc tggcctgccc agcttcgcgg ccttcgagcc ctaccacgag
    42001 aacgtcttct ccttccacga cgacctccag gacctcaagg acccggccca cggcgacagt
    42061 tacccgcccg acgccaccct gagctatctg gtcgtcggct ggtacagcga caccgacgag
    42121 gacatcctca acgtcgcggc cggcatcccc gggctgctgc ccccgggccc cgacggatcc
    42181 tcggccgccg acgtcatcgc cgccctcggc tggaccgtgg ccggacgcac cgccctcgtc
    42241 cagggaggca tgggcaccgc gaccgggcac gacgtgacga acgtcctcga ccaccaggag
    42301 gacacctact acctgagcga gaaggcgccg gtccgctcgg accgcatcac cgtcgacctc
    42361 ggcagcgtcc agcaggtcag ctcgctgcac gtgctggtgg gcgacccgga cgggcagcac
    42421 tccctgcccg ccgtacgcgt ccagacgtcc gtggacaacg tcaactggcc ttccgcccac
    42481 taccaggact tcgacgccgg cacccccgtc atcgagtaca cccccgagcg gccggtcacc
    42541 gcccgctacg tgcaactgtg gatgctggag tccgggtccg ggcccgccgc cgtgcggcgc
    42601 ctcgaggcca ccgccgcccc ccaggcgacg cgaagcctgt accacggcac cgcgctcggc
    42661 ctggagtggg agcgcgaagg cgaagccccc gacgacgccc gccccgacgc cacccatacc
    42721 aagatcgcgt tcgggcacag caccggcgag gccgccacca tgctgatcgg ccaccagact
    42781 cgctcgccgc gcaccgccca gctcttcagc gcgctctacc acggcacact ggacaccttc
    42841 gacggcgccg ccggggaccg cgacctggcc gaagtcaccc accgcagctg gttctccggc
    42901 agcgacggcg gtcacacctg gcagatcgtc ccccgcgacg accgggagcc tgactccgga
    42961 cgctccggga cggtggacga cgatccgttc ccgctggacg aactcaacgc ggcgcaggcc
    43021 gagtacgacc acctcctgcg gcagctgacg gaacaccagt ggcgggtctg ggcgctgtac
    43081 tggctacgga acctgcccga cgtggaacgc ccgggtgacc tgccctccga cttcgacacc
    43141 acatgcgacg agctgctcgc ccccgacggc gacggcccgg cgaatcaggc caaagaggct
    43201 caggcgcggc tccgcgaact ccgggaccac attccgcagg cggcggccgg gcaggacctc
    43261 caggacgcca tcgacgcctg ggccaccgcg aggggcctgg ccgaccgtct ccagctcaaa
    43321 cgactgcccc aggacagctt ctacaagccc gccgaccccg tcgtcctcat cgaaggcacc
    43381 ggcggcggca ccgtcccgct cacccgtgac cgcgacaacc cgctgccctg ccgggtgcct
    43441 tcccacctgc tctccgaggt caagatcggc gcgaactgga cggcgccgcc tgccagtccg
    43501 cccgaccccg gcatcaccgg actgcccgat gcctgcacgg acctgctcaa ggagttcgcc
    43561 ctcctggacg aggccgcacg caccgccgac aacggccaca cggccctgca caccatcacc
    43621 cagaaccccg cgacccacgc caggggccca ctggccgagt actgcgcacc gtggcgccag
    43681 ccgtggctgc cgatgctgct gatgtggaag ctgaattact tccccacccc gtaccacacc
    43741 gccgacggct accactggac cttcaccgcg cccccgcccg gcagcgaact ggacacctac
    43801 agctacctct ggaacggcac cggcaccctg aaagccgact tcgagagcga gggcgacgtc
    43861 ctcaaccggc tcttccgctc ccgcgcctac ctcgccccca ccaccgtcta cgtgctgcgc
    43921 gaacaactgt cccgctaccg ggccggttac ccgagcgtca acaccgcggg cctggccgcg
    43981 ctgcgcaggg agctcgaacc cctggacgtc ctctcccaga ccctcgacgg cttcaacgac
    44041 tggctgctgc aactcgacgg cggcgctcaa gtgcccaccg agcccgagat cgccgcgctc
    44101 gccggggagc agaaccacgt tcccgacccg gccggcgggc cccaccagaa gcgcttccag
    44161 cccgtacgcg cggggcagtt cttcctcacc gacctgcgta tcgtcgacca cttcggccgc
    44221 tgcgccgacc tggtcacctc cggcgcgagc ggcaactggt acgaccagta ccccctgaaa
    44281 accccctcgg tcaccccgag ccacgacctc tacaccgagc cccggctgat caaccccgag
    44341 cggttcgtcc agctcccgcc ccgcatcctc caggacaccc ggctggcgat cgcccaggaa
    44401 ccatccggcc aggccgacgg cctcgcgggc ctgctcctgg tcaactacct cgaccggacc
    44461 ctgggcgtgt acggcacgac cgggcaggcc ctgggagaac tgcgcaccgt caccacgagc
    44521 ggcgataccc gggtcgcggt ctacaccccg ctgccgcact ccccgtacac cggtcacacc
    44581 gatccccggt tcgccaccga tcacccgcag ttggccgcct tcctgaccgg cctgctcgac
    44641 cgcgacgact ccgccggcgc cttcggagcc ctgctcgcca ccatcgacaa gagcttgcgc
    44701 gccctcgtcg cccccgcggc cgaggacagc cggctgcccg gcctgctcat cggacggccc
    44761 gtcgcgctcg tccacgccac cctggacctc gaactgcacc acccgctgcc ggccgatccg
    44821 tcctgggaca ccgtcctcca cccgctcggc gcctccgcgg acgacgacac ctgggcgatc
    44881 cggctgggcg acccgcacgc cctggacgac gggctcatcg gctacttcag cgccgatccc
    44941 ggccaaccgg tcgactacgg actgctgcga gccctcgatc ccgccctcga ccacgactac
    45001 ctccaggcga ccaccaacgg cagcgacctc gccctgcccg tccgacccgc cacccgcccg
    45061 tgcacgcgtc acgtcaccct gctcgcccac ccccacctgc ccgtccacgc caccactgac
    45121 atcctcccgg tccactccct gcggctcgat gcggagcgcg tccaccaggc actcgccgcc
    45181 gtccgtgcct ccttccgcct caacccgctc ctcgccacca cccgcgaccg gcgaagcctc
    45241 ggcacgacca tgaccgaaga cccggaccac ccgctgagca acatctcggg cagcggggag
    45301 cccgcggcag agttccgcag tctggacgtt cctgcggtcg gcagcaccat caccctggac
    45361 ctgggcgctg tccagcagct caccggctac tccctccgga caggaaccgc cgggggcgga
    45421 agctggccgg gtaccccggt cctggagtcg tccgtcaccg gcgacgacga cggatgggag
    45481 ccgcgggcct tcaacgcccg acagccggtg aacgagcaca ccctcgccgc cccggtcccc
    45541 gcccgttatc tgcgtctgcg gctcaccacc gacgccgacg gcattttcgg catgcggacc
    45601 ttccgggcca cctgtacccc cgacgatgcg gccctggtcg tcccgccgct gtcggcacgt
    45661 cacggcacct ggagctgggc ccagccgcag gccaccggga ccgagcaact cgactgggac
    45721 gagcgcctgc tgatccctgc cgaccatctc gcccaccccg acgacgcgat gcccaccgcg
    45781 cgcgccggct acctccagct ccaccccagc acccggcagg ccgaccccga accgacgtcc
    45841 cagtcctgac gaaacaccag gagaccgcca ccgcatgacc gagtccgccg ccacggcacc
    45901 cctgcgctac acgctgacca cgttcccgcc cgtgctgacc caggccgccc ccgaccgtcc
    45961 cagccagggc cggctggaga tcaaggtctt ccgcgacccc caagcggtgc agacgaccgc
    46021 cggctgccgc agcatcaccg tcgaggtccc gaccggcgac cggcccgatg ccctcaccga
    46081 ccggcccgac cgcatcgacg ccacctacgg cgctccacac ggccgtacct ggcacatccg
    46141 taagagcatc tcccacagcg accgcaccgt cttcgtctgc accccggaaa acccgcgcca
    46201 cgaagccgtc ttcaacgaca ccgcgacgtt caccctcatc ctcgaccgca tcccgctgac
    46261 cggctcgccc agcaccgtcg gtctgcgcat caccgacgaa tcggccaccg gatccgagac
    46321 acacacccgc cgcagcaccg acctgcggct caccgttcag cgggcacccg acggcgggtc
    46381 ctgacccgtt cggatccgac cacccgcgcg agttcgtacc cgcccatcca cgttcctgcc
    46441 gccgaccgac cccgaccgcc ctgaccgccc cgactccccg agtccgcggg tgtccgccct
    46501 gggaggccct gccgtgtatc ccaccacctc cgacgccccg ctgtcggtca cctcacagac
    46561 cactccgcct acgcacttca ccgtctccac ggccgaggag gtcaagcgcg gcaccgtctt
    46621 cctgaccttc gccaaacctg ccgcagcccc ggacgtgaca tgtgcggaga tcagcgtctc
    46681 gctgccgcgt ggggacgcgg ccacggacct ggtcaacgac gaagcgcgcg ccaactacac
    46741 gctcatcgac gactacccac gcgacagcac cggcgcggca tggtccatcc accggctgcc
    46801 tgccgccccc gtgacgaccg ctcccgaatg gggcgaggca cccggccacg agttcaccaa
    46861 catcttcgac ccccgagacg acttctacta ccggaccacc ggactcgtcc cgaaggactc
    46921 cgccctggtc gtcgactacg gggtcgacca ggacatcacc accctggaca tcgcgaccgg
    46981 cttcaccaac ggccgcaaca aggtccagat gctgcttctc cagtcctcga tggacgggct
    47041 gcactggaac aacgtcgacg agcaccccgt ccaggacacc ttgcgcatcg agcgcacctt
    47101 cgatccaccg ctgcacgccc gctatctgag gatcttcacc atcgtcgaac cgtcgaacga
    47161 gggctacgcc gtcgtccggc gcttcctggc caaccaaggc actcggactc gctcagccga
    47221 cgaccccgtg accttcgtgt gcaccccgga cgacggagcg gcggtcttcg acgcctcccg
    47281 cgacttcacc ctgatcctgt ccaacatccc gatcaaccag acactcggca ccgccgccct
    47341 ggagatcacg cagacggtga tcgccggcgg cggcgaagtc cgccacacca caagcctgga
    47401 cgggttcgag aaggccgata acgccttcgt cttcgagaac ttctccagca agcagccccg
    47461 cgtcgacaac ggcgaccatg tcaccctgca ctggacgggc agcccggcga actccgacta
    47521 ccacctctcc tgggacgacc ggaccgaacg gatcagcgtt cccgccggcc gggactgcag
    47581 cttcggtacg gctgacctgc ccaggttcgc cgggctcagc cgcacgacca cgttcgtcct
    47641 ggacgcacag acgatcaact cgtcgggtca gacagtccac cactaccagt ccaccacggt
    47701 gaccgtcgcc gaccccgaca tcgaggccgg aagcctcacc gccaccgacc ggctcgcggt
    47761 ccgggcaggc ggtaccgaca cgttcctcgc ccgaagcgac gaggccggca cgcatgcgct
    47821 caccgcccac gccgaaggag acgtcacgat catcgcctga cccagcgccg gcaggtttcc
    47881 gctccacgcc gactcgcctc aggagtcccc atgagctccc gcagcatgac cgtcgaccgg
    47941 ctgctgacag ccgtgcccga cgaccccgca cccctcgcgg tctccaccgc cagcaagacc
    48001 aaactcggtg tcatccggct caggttcagc aaggccgcgg gcgtcccgaa cgtcgagtgc
    48061 acccggatcg ccgtcacgat ccccgtgggt gacaccgaca ccgacctcac cagcaacccc
    48121 gggaacatcg actacaagta ctccagcaac gggaactggc gcatcgccgc cagcagcgac
    48181 cggaccacct acgtgtgcac gccgtccggc ccgggcggga aattcgtctt caccgacgcc
    48241 gcccacttca cgctcaccct cgacgccatc ccggtgagcc gcctgcccgg cgaagcacag
    48301 ttgacgctca cggccaacgc cacgacgaat caaaccgacg gggaggactg gaccgtgccg
    48361 atcaccaagt ccgtggacga tttcttcttc ttccgtgctt tctcctgtga acagccacag
    48421 atccccaaca acggtgcggt gaccctgcgc tgggaaggca gcgagaacga gaccgagtac
    48481 tggctgtcct acgacggccg agagccccag caggtgtccg gtcagagcac gcggatcgaa
    48541 gggatcacgg acaccaccac gttcgtcctc gacgcgcgaa cgccgaaccc ggacaccaag
    48601 gaattcgacc agcaccacta cctgtccagc acggtcaccg tcaaagaacc caccatcgtg
    48661 gccaaggaac tcacggccaa gaaggtcaac gttcccgaca ccttcaccgc ggacagcaac
    48721 gacaagacca ccacgctcca cggccgtacg accttcgagg aggacgtcac cgtcatggcc
    48781 cggctcatcg tgcacgacgc catcaccaac gaagcaggca ccgtccggat cgacgccggc
    48841 tccgggaaca tcaccaccac cggaaccgtc cagggggccg gcttgaaggc cggcaccagc
    48901 tatgggatcg cgagcaatgg ggcgatcacc gggtccggcc tcaatgccgg cagcggcgac
    48961 atcaccacca ccggagtcgt caagggcgcc agtctgaagg cgggcaccag ctatgggatc
    49021 gcgagcaatg gggcggtcac cgggtccggc ctcaatgcag gcagcggcga catcaccacc
    49081 accggagtcg tcaagggcgc cagcttgaag gcgggcacca gctatgggat cg
//
