LOCUS       NZ_CP050976            22105 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6836089
            Orig. end                         :: 6858194
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22105
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22105
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22105
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12105](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12105
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            443..1564
                     /locus_tag="HEP86_RS30515"
                     /old_locus_tag="HEP86_30515"
     CDS             443..1564
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088802.1"
                     /locus_tag="HEP86_RS30515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30515"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_248001366.1"
                     /transl_table=11
                     /translation="MDSKGFEVPRPPAWMRWLPVAYVAFVLLLETVTPTPWAVSFLLIA
                     LPVIAAYSLGPVLVAAATVFAVLLEGVLAGTPCCTGHNIHMLWENHHVAAYVATGLVGV
                     LGVALAAHRRRQEQYLVRARSVAEALMRTLLRPVPHRVGRLLAAGLYRSGEVGTMVGGD
                     LYDLRATPAGERAIIGDVRGKGLQAVRTVADILGSFREAVHEPGELPAVAARMERRMAR
                     EAEELPDDELFVTAALIEYDAAAQRVTIINHGHIEPVLISRGEVTPLIGPPALPLGLGA
                     LADEEPVAYTHPFTCGDVLLLCTDGVIEARDHNGAFYPLLDRLRDRFGDRPAPGPADVI
                     DFLNTDLPRHTRVFHDDVALLALAPDGGGGGGA"
     gene            complement(1599..2132)
                     /locus_tag="HEP86_RS30520"
                     /old_locus_tag="HEP86_30520"
     CDS             complement(1599..2132)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537019.1"
                     /locus_tag="HEP86_RS30520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30520"
                     /product="hypothetical protein"
                     /protein_id="WP_168481799.1"
                     /transl_table=11
                     /translation="MGDSTIWTLAIAAVTGGTAVLASWVTSRGSARAARIQAETAARSQ
                     RAERLRESRRTAYLDLIEQTHRMGELFWEISTVLRLPRSESRASTLGELQDREVAEYAR
                     IRRCARVVELEGPQSAAAAALALQKATRPFYAALSADLTGDPDGQDSFDAAYRPYWKAL
                     EEFVDAARDAHQTD"
     gene            complement(2175..3197)
                     /locus_tag="HEP86_RS30525"
                     /old_locus_tag="HEP86_30525"
     CDS             complement(2175..3197)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016910272.1"
                     /locus_tag="HEP86_RS30525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30525"
                     /product="hypothetical protein"
                     /protein_id="WP_248001367.1"
                     /transl_table=11
                     /translation="MVRYTSAHTTGGTAAGAGRTAAHPRRRTGRATALGAAALALALPL
                     TACSAGGGSDAPTGGSSSSAAGSAPSPTPSPTADPATYRHALTDALRPLDSALRAVDGA
                     HEGGPLDKALNTAAGKAETAADALEAVAAPDNALSGTSQLATALRALGQDLRSARGGVG
                     RCATSPRVELDTAHGPQSVKEAARALKALGYDTALRLPRTERAQHRRPANGTFVRDGSR
                     GGLGRLTVNNGTSSDAVVTLTRGTRTAFSLYVRKGAKATVRSVNSGAYTVYFTTGEDWN
                     GGKRSFTRGCSFEKFDDKANFRTVRVSGGTQYTVLTFTLNKVFGGNASTSTVPPGEFPS
                     "
     gene            3756..4837
                     /locus_tag="HEP86_RS30530"
                     /old_locus_tag="HEP86_30530"
                     /pseudo=""
     CDS             3756..4837
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602565.1"
                     /locus_tag="HEP86_RS30530"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30530"
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTDDERGRGRLTEPAAPDGPPHTPATPAPGAPGPHAPLPDAVTC
                     HALRYAFGETKAVDGVDLSVRTGEVFGLLGPNGAGKTTAIRCITTLLPVPAGMVRVFGH
                     DAAKERMAVRRLLGYVPQQLSADAGLTGRENVALFARVFDVSRRERAARVTQALAAVGL
                     TEAAGRLAKTYSGGMIRRLELAQALVSAPRLLMLDEPTIGLDPIARTSVWEHINAVRAA
                     TGMTVLVTTHYMDEADQYCDRLALMHQGRIRALGTPEELRSALRARRRAARTSAARQPA
                     PHTPSDAPDTATPTASAASPSTPAAPATSSSPSSAPRARPTPRRPWRTSSGTSPAAAST
                     SSQETSAMSEAPAAPPTGSA"
     gene            4797..5660
                     /locus_tag="HEP86_RS30535"
                     /old_locus_tag="HEP86_30535"
     CDS             4797..5660
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980847.1"
                     /locus_tag="HEP86_RS30535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30535"
                     /product="ABC transporter permease"
                     /protein_id="WP_168481800.1"
                     /transl_table=11
                     /translation="MSEAPAAPPTGSADTASGADRLDLLLVPPRARTGWRVLTARVVAM
                     CVVELQKLRHDRTELYTRAVQPALWLLVFGETFTRLKAIPTGGTPYIDYLAPGIIAQSA
                     MFIAIFYGIMIIWERDAGILTKLLVTPTPRSALIAGKAFAAGVKALIQAVVVIVIAALL
                     GVAMTWNPLRLLAVAVAVVLGSAFFSCLSMTIAGIVLTRDRLMGIGQAITMPLFFASNA
                     LYPVAIMPGWLQTVSLINPLSYQVDALRGLLLGTHAHLALDYAVLVGAAALGIAAASSL
                     LGRLAR"
     gene            complement(5691..6944)
                     /locus_tag="HEP86_RS30540"
                     /old_locus_tag="HEP86_30540"
     CDS             complement(5691..6944)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_28"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556326.1"
                     /locus_tag="HEP86_RS30540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30540"
                     /product="glycosyltransferase"
                     /protein_id="WP_168481801.1"
                     /sec_met_domain="Glyco_transf_28 (E-value: 9.6e-12,
                     bitscore: 43.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLIVATGTQGDISPFLGLATRLRAAGHPVALATYEAFAEQVRR
                     NNCEFRPLPGDPRALGVAEQGRLKKAGIGDSLRAGVWLKNIRRHLEALGDGLIAAAEKD
                     TDLLLCSGLTMFHSYHLAKALGIPSMGLGLQPLHPTGDFPPPIGVPSLGAWANRSLGQL
                     MFATGLTPWSSSPEFCRKIAVPPMNTAETFRRTTDERWPVHYGFSPTVVRRPADWRPGV
                     EVVGYWWPPEQPAWRPSQELLDFLDDGPAPVRIGLGSVGDPRDAERIGELAVDALRRAR
                     VRGVVQTGWAGLDARDDAVLTIGDAPHDWLFPRMAAVVHHMGAGTTGAGLRAGVPAVGL
                     PAFGDAPFWARRVVAMGAGPGFLPLGTLHAGRLAELIRTAVDRPQYARRSRLLAAKLAQ
                     EDGAGRTVEAVDRLLNSG"
     misc_feature    complement(6570..6572)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7179..8516
                     /locus_tag="HEP86_RS30545"
                     /old_locus_tag="HEP86_30545"
     CDS             7179..8516
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="HEP86_RS30545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30545"
                     /product="cytochrome P450"
                     /protein_id="WP_168481802.1"
                     /sec_met_domain="p450 (E-value: 5e-92, bitscore: 307.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRLSLRENLVGLAEMRRDQLAFLVRSVRTHGDIFHMRLGGLPTV
                     MVNHPDYLQHVLVDNHQNYDKDNFLYRATRTVLREGLIANKGGEPWRRHRRIMQPSFSR
                     SSVADFTTNISDLTGDLLRQWEEPAGRGAVVEVTTEVANLALRIVLRALFGVDADDRGR
                     RFERDFLEVNAIAGDFFRFPFPPLSWYSPSRNRLRQLIREMDGFIAYLIDARLARESEK
                     PDLFTLLLNAMDEETGTGLTHEQLANEILAMIIAGYETSSNSISWIFYQLAAYPDIQRR
                     VHDEVDGVLDGRVPTLDDLPRLTYTRMVIDETLRLFTPAWQTMRHAVDDDVIGGYRIPR
                     GTDVYLNLFTFHRHPEFWPDPDRFDPERFTPEEIARRPRHVYQPFGSGPRHCLGKHFAL
                     TELHIITAMLAQTFHITRPEGQAPVGFAPLITLHPKGGIHLRLHRR"
     gene            8538..9941
                     /locus_tag="HEP86_RS30550"
                     /old_locus_tag="HEP86_30550"
     CDS             8538..9941
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="HEP86_RS30550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30550"
                     /product="cytochrome P450"
                     /protein_id="WP_168481803.1"
                     /sec_met_domain="p450 (E-value: 4.9e-96, bitscore: 321.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLTPRTRAARRTPSLREIPTVTARDGIGGTLAFKRDQLAFLGDG
                     LARHGDIFRFRPLGLPMVMVNHPDHIRHILVDKGEQYDKDAAIFKVVRPVLRNGLIANA
                     DMALWRRQRRMMAPHFTPRTVSAFARNMTDETVQMLERWEPRTAAGDTLDITDEIGQLA
                     LRIVNRSLFSADVGTAAQAFERAFGEANSILGAFFRFPFPPLSVPTPSHRRLRRAINGM
                     DAFVSGFIKKRLNDEVATGEETDLLTLLLHSVDEEDGKGMDLEQLHHEVLNICIGAYET
                     TTNTLSWAFYLLARHPEIEERLHAEVDEVLGGRVPAFEDLPKLVYTRMVVEETLRIYSP
                     AYQFMRRAREEDEIDGYRMPAGANVLINSYFLHRHPDFWEEPERFVPERFTPEQVAQRP
                     KHVYIPFGSGHRICIGKHFALTELTLVLATVARHHRLVMPEGAAEVHPEALITLHPKGG
                     VHLRPEPRG"
     gene            10001..11014
                     /locus_tag="HEP86_RS30555"
                     /old_locus_tag="HEP86_30555"
     CDS             10001..11014
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524259.1"
                     /locus_tag="HEP86_RS30555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30555"
                     /product="terpene cyclase"
                     /protein_id="WP_168481804.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-83, bitscore: 280.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDIFHPFPYRISPHVAEAREHLTDWTRRIGLIEREAARKRFAKA
                     DFGWFAAMVYPTADATRLNLMADWFAWLFLVDDQLDDGSIGRSPERARDIVDGMRVVLE
                     SPDHGAAAAADRDGPVAVSALADLWLRTAPHATAHWRRRFVQHLDDCLTVAATWEAGNR
                     VTGTVPDEETYIEMRRHTGAIYVCMDFIDIVERIDIPDSLYTGAQFQAALDAACNVVCW
                     TNDVYSLAKERALGEVHNLVHIVEHHRGLDTPGALDHVCAATSTETTLFLEKERELLAA
                     RPEHHAVLVPTLAGMRTWMRGNLDWSRSTKRYRPVEGDEEIRPEEYLEASLMKVDQ"
     gene            11011..12105
                     /locus_tag="HEP86_RS30560"
                     /old_locus_tag="HEP86_30560"
     CDS             11011..12105
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145719.1"
                     /locus_tag="HEP86_RS30560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30560"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_168481805.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.3e-66, bitscore:
                     221.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTGERPALAQPGSAGPGNAAAPGNSAPDAWHLLKTARELTEPE
                     LRKAVDRLAEPVRSVAAYHFGWSDECGRPANGEGGKGVRAALVLAAAQALGTVAEEAVA
                     PAAAVELVHNFSVVHDDLMDGDLLRRGRSTAWSQFGSTQAILAGDALLAVAVDTLAHRC
                     PQGGPEAVRELSGSLLALVAGQGADLAFETRADVGLAECLEMAAGKTASLLAAACALGA
                     LAARAGAERVDALRQFGRHLGLAFQLVDDLLGIWGDTAVTGKPVGSDLRSRKKSLPVVA
                     ALSSGTPAGDRLAALYHRTEPLDDAELRTAARLIEEAGGRRWAQEEAERQRTAAVTRLA
                     TAGVTPGGTRALTALADLITRRDV"
     gene            complement(12358..13515)
                     /locus_tag="HEP86_RS30565"
                     /old_locus_tag="HEP86_30565"
     CDS             complement(12358..13515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088813.1"
                     /locus_tag="HEP86_RS30565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30565"
                     /product="magnesium and cobalt transport protein CorA"
                     /protein_id="WP_211117449.1"
                     /transl_table=11
                     /translation="MSSEPPGRRPRGLRGLRKPAKKRPAGPPPAETTDGSAAPEPPAET
                     PSSIITAALYRDGHRVSTHETLADAFRQQRATSGTLAWIGLHRPTSAELVTLASEFDLH
                     PLAIEDALEAHQRPKLERYGGTLFVVLRAARYLDDPEEVDFGELHVFVGRDFVITVRHG
                     GAPDLSAVRRRMEDTPELLKRGPEAVLYAILDAVVDGYAPVVDGVQTDIDEIETEVFGG
                     DPRVSRRIYELSREVVEFQRATRPLNGMLESLTAGFEKYAIDEELRRYLRDVADHVLHT
                     TERVDGFRQALQDILTVNATLVNQQQNAEMRALAEAGFEQNEEVKKISAWAAILFAPTL
                     VGTIYGMNFDEMPELHWVFGYPFALVLMAVVCTSLYLIFKRRRWL"
     gene            13736..14125
                     /locus_tag="HEP86_RS30570"
                     /old_locus_tag="HEP86_30570"
     CDS             13736..14125
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088814.1"
                     /locus_tag="HEP86_RS30570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30570"
                     /product="cell division protein SepF"
                     /protein_id="WP_168481806.1"
                     /transl_table=11
                     /translation="MNGPDATDEQWEGLAEVVPLRSSSGWPSWPDHRALPEEEPAEQLR
                     RFIVIRVQTFADAREVAEYLMAQIPVLLDLSSADADVAKRILDFSSGVVFGLGSGMHRV
                     DTNVFLLAPVGTEVAETALGGVPRS"
     gene            14181..>14804
                     /locus_tag="HEP86_RS41010"
                     /pseudo=""
     CDS             14181..>14804
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714505.1"
                     /locus_tag="HEP86_RS41010"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="biotin transporter BioY"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNTETVRPAVTELRLSAFKTHRGVTLPLTRLTLLSGESGSGKSSA
                     LQAYEILARLGSGESLARAVGEVAGSPAACVPAGARPDAQGRRGFRIGCTVDGPAGPVS
                     LDLAVQAEPELRIVGERLTGGGETLLTTALTDPDRPTVQAAWHTAGATPVTRAPLPDDR
                     LGTSLLPLRVAGKTAGQRLVLAAAEQVVVALRSAFVCDPRPEVMR"
     misc_feature    14217..14219
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14936..15634
                     /locus_tag="HEP86_RS41015"
     CDS             14936..15634
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004923939.1"
                     /locus_tag="HEP86_RS41015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_348772254.1"
                     /transl_table=11
                     /translation="MRGGAGKPGGAGGAAGAWGPRKRTGSGGEAGGWARDTEGARAEGR
                     LRSSCDNLPAVLERTSQECARRHAVLVAAVREACAGPVEGLRAVPWQAGGTGESPADAA
                     APAGPVGTAGPRAGVAGVRAVLDRGELGELPVEQLGDGELRFLALALVLLTGPEVLAMD
                     PVGEVPSAHQQMTVMADGMDRCMDARQARELVSLALRMTDRGHVRLLGTVRDPSVAEGL
                     PGVQVLHLGV"
     gene            15631..15990
                     /locus_tag="HEP86_RS30580"
                     /old_locus_tag="HEP86_30580"
     CDS             15631..15990
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088816.1"
                     /locus_tag="HEP86_RS30580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30580"
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="WP_168481807.1"
                     /transl_table=11
                     /translation="MSEDLHALQRRLAEFAAARDWQQYHTPKNLAAALSVEAAELVEIF
                     QWLTPEESAKVMTNPGKAGRVEDEVADVLAYLLQFCEALGIDALAALAAKIERNESRFP
                     AVRSARPDRPREGEE"
     gene            16374..16832
                     /locus_tag="HEP86_RS30585"
                     /old_locus_tag="HEP86_30585"
     CDS             16374..16832
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088817.1"
                     /locus_tag="HEP86_RS30585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30585"
                     /product="DUF6099 family protein"
                     /protein_id="WP_168481808.1"
                     /transl_table=11
                     /translation="MDAVRIIAASRRGLAEANTVQGVIVEAWQAQALAEAVGSHLAIFG
                     PYEVRSRARGLGDAGGRFSGGLLCPASVTGGGLRAAQLSEVRDAKAALTGLCLLLREVC
                     EALVAVVLLADEDGMYWTCVEAMDTVDESRDRVAGILEKLEVRDRNPA"
     misc_feature    16650..16652
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17018..17941
                     /locus_tag="HEP86_RS30590"
                     /old_locus_tag="HEP86_30590"
     CDS             17018..17941
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612064.1"
                     /locus_tag="HEP86_RS30590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30590"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_168481809.1"
                     /transl_table=11
                     /translation="MDLRIFTEPQQGASYETLLKVAKATEDLGFDAFFRSDHYLRMGNA
                     DGLPGPTDAWITLAGLARETRRIRLGTLMTAGTFRLPGALAIQVAQVDQMSGGRVELGL
                     GAGWFEEEHKAYGIPFPKEKFGRLEEQLAIITGLWGTATGEEFSYDGTYYQLENSPALP
                     KPAQGKVPVLVGGHGATRTPRLAAQYADEFNIPFASLEDSARQFGRVRAAAEAAGRKGE
                     ELVYSNALVACVGRDDAEVARRAAAIGREVDELKANGLAGSPAEVVDKIGRYAAIGASR
                     VYLQMLDLDDLDHLELISTQVQSQLN"
     gene            18012..19667
                     /locus_tag="HEP86_RS30595"
                     /old_locus_tag="HEP86_30595"
     CDS             18012..19667
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345878.1"
                     /locus_tag="HEP86_RS30595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_30595"
                     /product="3' terminal RNA ribose 2'-O-methyltransferase
                     Hen1"
                     /protein_id="WP_248001368.1"
                     /transl_table=11
                     /translation="MFLTITTTGSADRPATDLGFLLHKHPDKAQRFSTSQGTAHVLYPD
                     ADAQRCTAALLLEVDPIALVRKSRGKGRGGAPDSALGQYVNDRPYAASSLLAVALRTVF
                     ASAMKGQCTARPELVAQALPLRIEVPVLPARGGPELVDKLFRPLGWTVRAEPVPLDETF
                     PEWGDSRYVRLVLEGECRLSEALRHLYVLLPVLDDAKHYWVAPDEVDKLLRAGEGWLEG
                     HPEQRVIVGRYLARRWSLTRQAMERLELVRLAESDDVAAEELDNAVDEEADTEEKPVPL
                     AVRRREAILAVLRSAGAARVLDLGCGPGQLVGELLKEGQFTEIVGVDVSMRALHEARRR
                     LRLDRMSERQSARVRLVQGSLAYTDGRLKGYDAAVLSEVVEHVDPARLPALEYAVFGSA
                     RPGTVVVTTPNVEYNVRWESLPAGRVRHADHRFEWTREEFRQWAHGVAARHGYEVSFGP
                     VGPDDPEVGPPTQLAHFRRAGDDSSGPADSANSRQGRDPEGSGNGREGRGPEGGSREDR
                     QSEDSGSVRENRAPEGGSSAAGGSGSMRGKEVAA"
ORIGIN
        1 ggaacgagcc gacatcgtgg tcgaacacct tcgccagacg gccgagccgc tccagcgcga
       61 tatccgtctc gccccgctcc agaccggcca ggaaggacac cgacagccca cactcagcgg
      121 ccacttggcg aagcgacatc ccccgctgcg tacggagccg gtgcagcacc tcgccgggcg
      181 gcgggaagcc gagctccgga tcccgcgcgg gaggggtgga gggggccggg tctgccatgc
      241 ccgcatccta atgccggggc aggggacatg ccgctgacgg cctaatgagc gggctggtct
      301 gtttgggggc gtcaggctgt ggctcttggt cgcggtcgtg tggggagccc gtgtggacgg
      361 atcgggtgag tggatcgctg ggcggtccgg ccgtgaccgg cggcggggcc gtggacgtac
      421 ggcggggcgg cttgcggaga ccgtggacag caagggcttc gaggtgcccc gtccgcccgc
      481 gtggatgcgc tggctgcccg ttgcctatgt ggcgttcgtc ctgctgctcg aaaccgtcac
      541 ccccacgccg tgggcggtga gcttcctgct catcgccctg ccggtgatcg ccgcctactc
      601 cctcggcccg gtgctggtcg cggcggccac ggtcttcgcg gtgctgctgg agggcgtgtt
      661 ggcgggcacc ccgtgctgta ccggccacaa catccatatg ttgtgggaga accaccatgt
      721 cgccgcgtat gtcgccaccg gtctggtcgg tgtgctcggg gtggcgctgg cggcccaccg
      781 ccggcgccag gagcagtatc tggtgcgcgc ccgctcggtc gccgaggccc tgatgcggac
      841 cctgctgcgg ccggtgccgc accgggtcgg ccgccttctc gcggccgggc tgtaccggtc
      901 cggggaggtc ggcaccatgg tcggcggtga cctctacgac ctccgcgcca ccccggccgg
      961 tgagcgcgcc atcatcggcg acgtccgcgg caagggactc caggccgtcc gtacggtcgc
     1021 cgatatcctc ggcagcttcc gtgaggcggt ccatgagccg ggtgagctgc cggccgtcgc
     1081 ggcccgtatg gagcggcgca tggcccgtga ggccgaagag cttcccgatg acgagctgtt
     1141 cgtcaccgcc gcgctgatcg agtacgacgc cgccgcccag cgagtgacga tcatcaacca
     1201 tgggcacatc gagccggtcc tgatctcccg tggcgaggtg acgcccctca tcgggccgcc
     1261 tgcgctcccg ctcggcctgg gcgccctggc cgatgaggag cccgtcgcct acacccaccc
     1321 cttcacctgc ggtgatgtcc ttcttctgtg caccgacggg gtgatcgagg cccgcgacca
     1381 caacggcgcc ttctacccgc ttctcgaccg tctccgtgac cgcttcggcg atcggcccgc
     1441 gcccggcccc gccgatgtca tcgacttcct caacaccgat ctgccccgcc acacccgcgt
     1501 cttccacgac gatgtcgctc tgctcgccct ggcgcctgat ggcggcggcg gtggaggggc
     1561 gtaggcgagc ggttggcgtg gtgccgtggc ggttcgcgtc agtccgtctg gtgggcgtcc
     1621 cgtgccgcgt cgacgaactc ctccagggct ttccagtagg ggcggtaggc ggcgtcgaag
     1681 gagtcctggc cgtcggggtc gccggtcagg tccgcgctga gggcggcgta gaacgggcgg
     1741 gtcgccttct ggagggcgag ggccgcggcg gcggccgact gcgggccctc cagttcgacg
     1801 acccgggcgc agcggcggat cctcgcgtac tcggcgacct cccggtcctg gagttcgccg
     1861 agtgtggagg cacgggactc tgagcggggg agccgcagca cggtggagat ctcccagaac
     1921 aactcgccca tccggtgggt ctgttcgatc agatccagat aggcggtgcg gcggctctcc
     1981 cgcagccgct cggcacgctg cgagcgcgcg gcggtctcgg cctggatcct ggcggcccgc
     2041 gcgctgccgc ggctggtgac ccaactggcg agcaccgccg tgccgccggt caccgccgcg
     2101 attgccagag tccatatcgt gctgtcgccc acgtgacgtc accctatcga gccgctccgg
     2161 cgcaccgggc gccgctacga ggggaattcg cccggcggca ccgtgctcgt ggaagcgttg
     2221 ccgccgaaca ccttgttcag ggtgaaggtc agcaccgtgt actgcgtccc gccggacacc
     2281 cgcaccgtcc ggaagttcgc cttgtcgtcg aacttctcga agctgcagcc gcgggtgaag
     2341 gagcgcttcc cgccgttcca gtcctcgccg gtggtgaagt acaccgtgta cgcaccgctg
     2401 ttgacgctgc ggacggtcgc cttggcgccc ttgcggacgt acagggagaa cgccgtgcgg
     2461 gtgccgcggg tcagcgtcac caccgcatcg gagctggtgc cgttgttgac ggtcagccgg
     2521 cccagcccgc cccggctgcc gtcgcgcacg aaggtgccgt tcgccggccg ccggtgctgg
     2581 gcccgctccg tacgcggcag ccgcagcgcg gtgtcatagc cgagggcctt gagcgcgcgg
     2641 gcggcctcct tgacgctctg cgggccgtgc gccgtgtcga gttcgacgcg gggtgaggtg
     2701 gcgcagcggc cgacgccgcc gcgggcactg cgcagatcct gtcccaaggc gcgcagggcg
     2761 gtggcgagtt ggctggtgcc cgagagggcg ttgtccggtg cggcgaccgc ctccagggcg
     2821 tcggcggcgg tctcggcctt gcccgcagcg gtgttcagcg ccttgtccag gggaccgccc
     2881 tcgtgcgcac cgtcgaccgc gcgcagcgcg ctgtcgagcg ggcggagggc gtcggtcagc
     2941 gcatgacggt aggtggcggg gtcggcggtc ggcgatgggg tgggggacgg tgccgaaccg
     3001 gccgccgagc tgcttgatcc gcccgttgga gcgtcgcttc ctccgcctgc cgaacaggcc
     3061 gtcagcggca gcgccagtgc gagggccgcc gcgcccagtg cggtggcccg gcccgtacgg
     3121 cggcgtgggt gggccgctgt ccggcccgct cccgccgccg tcccgcccgt cgtgtgcgca
     3181 gacgtgtacc tcaccatgag tcccccgatt cccccggtat cccccgacat ccggcaactg
     3241 ccgaaagaga caggcttctc ccaccacaag tggctgtcaa gtgggttgtc cggtacggca
     3301 gttgggcggg gtttgggggc agggcggggg cgggccgggg gcggcgctgg gatccggggg
     3361 cgcgccggga cgccttcctg ccgggcgcgg tatccgcgca ggccggaccg gtcgcggcgg
     3421 tggtccgggg cccgcccaaa gatcgcgccg ccggaagagg cgcctccgcc tccacctccg
     3481 cctccggaag ggagctgatc tctcgcgtgc cgggctgctt cgcggcgggc ccggtggggc
     3541 ggcgaggcgg cggggccgtc gcagcggagg cgaccggcgg gaccgtcgtg gcggcggtga
     3601 ccgcccggcc tcccggtggg ccgttcgata ccccgccccg cgcgcgttcc ggtctccgcc
     3661 gcccctcgga cctaaaatcg gaacatgccc gcagggggtt cccgacccgc ccgacgcggg
     3721 acgggccggt gtcccgcggc tgatccggag ggcccatgac caccgacgac gagcgagggc
     3781 ggggacggct caccgaaccg gcggcgccgg acgggccacc gcacaccccg gccacgcccg
     3841 ctcccggcgc ccccggtccg cacgcgcccc tccccgacgc tgtgacctgc cacgcgctgc
     3901 gctacgcgtt cggcgagacc aaggccgtgg acggcgtcga cctctccgtc cgcaccggtg
     3961 aggtcttcgg gctgctcggc ccgaacggcg cggggaaaac caccgcgatc cgctgtatca
     4021 ccaccctcct gcccgtcccg gccggcatgg tgcgggtctt cgggcatgac gcggcgaagg
     4081 agcggatggc ggtgcgccgg ctgctggggt acgtcccgca gcagctgtcc gcggacgccg
     4141 ggctgaccgg ccgggagaac gtcgcgctgt tcgcccgggt cttcgacgtc tcccgccgcg
     4201 agcgcgccgc ccgcgtcacc caggcgctgg cggcggtcgg cctcaccgaa gcggccggcc
     4261 ggctcgccaa gacgtactcc ggcggcatga tccgccgcct cgaactcgcc caggccctgg
     4321 tcagcgcgcc ccggctgctg atgctcgacg agccgacgat cggcctcgac ccgatcgccc
     4381 gtaccagcgt ctgggaacac atcaacgccg tacgggccgc caccggtatg accgtcctgg
     4441 tgaccacgca ctacatggac gaggccgacc agtactgcga ccgtctcgcc ctgatgcacc
     4501 agggccggat ccgtgccctc ggcacccctg aggagctgcg ctccgccctg cgcgcccgcc
     4561 gccgcgccgc ccggacctcg gccgcccgtc agccggcgcc ccacaccccg tccgacgccc
     4621 cggacaccgc caccccgacg gcctcggcag cctcaccctc cacccctgcc gccccggcca
     4681 cctcctcctc tccgtcgtcg gcccctcgcg cccgtccgac accgcgccga ccctggagga
     4741 cgtcttccgg gacgtcgccg gcagcggcct cgacgagcag tcaggagact tccgcgatgt
     4801 ccgaagcacc cgccgcaccg ccaaccgggt cggctgacac cgcctccggc gccgaccggc
     4861 tggacctgct gctggtcccg ccgcgcgccc gcaccggctg gcgggtgctg accgcccgcg
     4921 tcgtcgcgat gtgcgtggtc gaactgcaaa agctgcgcca cgaccgcacc gagctctaca
     4981 cccgcgccgt ccagcccgcc ctgtggctcc tggtgttcgg cgagaccttc acccgcctca
     5041 aagccatccc gaccggtggc accccgtaca tcgactatct ggcgcccggc atcatcgccc
     5101 agtccgccat gttcatcgcg atcttctacg gcatcatgat catctgggag cgggacgccg
     5161 gcatcctcac caagctgctg gtcaccccga ccccgcggtc cgcgctgatc gccggcaagg
     5221 ccttcgccgc cggggtgaag gcgctcatcc aggccgtggt ggtgatcgtc atcgccgccc
     5281 tgctcggtgt ggccatgacc tggaaccccc tccggctgct cgccgttgcc gtcgccgtgg
     5341 tcctcggctc ggccttcttc tcctgtctgt ccatgacgat cgccgggatc gtgctcaccc
     5401 gggaccggct gatgggcatc ggccaggcca tcaccatgcc gctgttcttc gcctccaacg
     5461 ccctctaccc ggtggcgatc atgcccggct ggctccagac ggtgagcctg atcaaccccc
     5521 tgagctacca ggtcgacgcc ctccgcggcc tcctcctggg cacccacgcc cacctggccc
     5581 tcgactacgc cgtcctggtg ggcgcggccg cactcggcat cgccgccgcc tcgtcgctcc
     5641 tggggcggct ggcccggtga gcctggccct cccgctccct acggcctccc tcagccggag
     5701 ttgagcagtc ggtccaccgc ctcgacggtg cgtccggcgc cgtcttcctg ggcgagcttc
     5761 gccgccagca ggcggctgcg tcgcgcgtac tggggccggt cgacggccgt gcggatcagt
     5821 tcggcgaggc ggccggcgtg cagggtgccg agcgggagga aaccggggcc ggcgcccatc
     5881 gccacgacgc ggcgagccca gaagggggcg tccccgaagg ccggcaggcc caccgcgggc
     5941 actcctgcgc gcaggcccgc gccggttgtg ccggcaccca tgtggtgcac cacggcggcc
     6001 atccgcggga acagccagtc gtgcggcgcg tcgccgatcg tgaggacggc gtcgtccctg
     6061 gcgtccagtc cggcccagcc ggtctggacg acgccccgca cccgtgcccg gcgcagcgcg
     6121 tcgacggcca gctcgccgat ccgttccgcg tcgcgcgggt cgcccacgct gcccaggccg
     6181 atgcgtacgg gggcggggcc gtcgtcgagg aagtccagaa gttcctggga cggccgccag
     6241 gcgggctgct cgggcggcca ccagtagccg accacctcca ccccgggacg ccagtcggcg
     6301 gggcggcgga ccacggtcgg gctgaagccg tagtggacgg gccaacgctc gtcggtcgta
     6361 cggcggaagg tctccgcggt gttcatcggg ggcaccgcga ttttcctgca gaattccggc
     6421 gagctcgacc agggggtcag cccggtggcg aacatcagct gtcccaggga gcggttggcc
     6481 caggcgccca gggaaggcac gccgatcggt ggtgggaagt ccccggtggg gtgcagcggc
     6541 tgaagtccca gtcccatgct gggaatccct aatgccttcg ccaagtggta gctgtgaaac
     6601 atggtcaggc cgctgcacaa cagcaggtcg gtgtccttct cggcggcggc gatcaaaccg
     6661 tcaccgagcg cttccagatg gcggcgtatg ttcttcagcc atacacctgc gcggagtgaa
     6721 tcgccgattc cggccttttt cagccggccc tgttcggcga cgcccagggc gcgggggtcg
     6781 cccggcagcg gacggaattc gcagttgttc cggcggactt gttcggcgaa tgcctcgtag
     6841 gtggcgagag caacggggtg tccggctgcc ctcagccggg tggccaggcc gaggaagggt
     6901 gagatgtcgc cctgggtgcc ggtggcaaca atgaggactg tcatggcggc atcgtagggt
     6961 ctggtccggt gagccatgag cggtttcccg tcggcgactc ggacggtcgg agagtccgcc
     7021 gcggcctgcg gatttcggaa gccgatcgat aacgaaacaa aatcttgaac ggctagcctt
     7081 cagagagttc ggcaccagct cctgacttcc aaggatcttc cgtgtccact gtttctgccc
     7141 gattagactc gcccgaaggc aaaaacccgc cacagcccgt gccgcgactg agcctgcgcg
     7201 agaatctcgt gggccttgcg gaaatgcggc gcgaccaact ggcgttcctg gtgcgctcgg
     7261 tgcggactca tggcgatatc ttccatatgc gtctgggcgg tctgcccacg gtgatggtca
     7321 atcaccctga ctatctccag cacgtcctgg tcgacaacca ccagaattac gacaaggaca
     7381 acttcctcta tcgcgccacc cggacagtgc tgcgcgaggg gctcatcgcg aacaagggcg
     7441 gcgagccatg gcgtcggcac cgccggatca tgcagccctc cttcagccgc tccagtgtcg
     7501 ccgacttcac cacgaacatc agcgatctga ccggcgacct gctgcgccag tgggaagagc
     7561 cggccggccg gggcgcggtg gtcgaggtga cgaccgaagt cgccaacctc gcgctgcgga
     7621 tcgtgctgcg cgcgctgttc ggggtcgacg cggacgaccg cggccggcgc ttcgagcggg
     7681 acttcctgga agtgaacgcc atcgcggggg acttcttccg gttccccttc ccaccgctgt
     7741 cctggtactc gccgtcccgg aaccggctcc ggcagctgat ccgggagatg gacggcttca
     7801 tcgcgtatct catcgatgcg cgcctggccc gggagagcga gaagcccgac ctgttcacgc
     7861 tgctgctcaa tgcgatggat gaggagaccg gcaccgggct cacccatgag caattggcca
     7921 atgagatcct ggccatgatc attgccggat atgaaacctc cagcaattcc atctcctgga
     7981 tcttctacca gctcgccgcg tacccggata tccagcgccg ggtgcacgat gaggtggacg
     8041 gtgtgctgga cggacgcgta cccactctcg acgatctgcc ccgtctgacc tacacccgca
     8101 tggtgatcga cgagacgctg cgcctgttca ccccggcgtg gcagaccatg cggcacgccg
     8161 tcgacgacga tgtcatcggc gggtaccgga ttccccgggg aaccgatgtc tatctgaatc
     8221 tcttcacctt ccaccggcac cccgaattct ggccggaccc ggaccggttc gatcccgagc
     8281 ggttcacccc ggaagaaatc gcccgacggc cgcggcacgt ctatcagccg ttcggaagcg
     8341 ggccccgcca ctgcctcggc aagcatttcg cgctgaccga actgcacatc atcacggcca
     8401 tgctcgccca gaccttccac atcacccggc cggagggcca ggccccggtg ggtttcgcgc
     8461 cgctgatcac cttgcacccc aagggcggca tccatctccg gctgcaccgt cgctgacgca
     8521 tcgcaaagag gtcatgaatg cccctgactc cgcgtacccg tgccgcgcgc cggacgcctt
     8581 ccctcagaga gattcccacg gtcacggcgc gggacggtat cggcggaacg ctggccttca
     8641 aacgtgacca gctcgccttt ctcggcgacg ggctggcgcg gcacggcgac atcttccggt
     8701 tccgcccgct cggcctcccc atggtcatgg tcaaccaccc ggaccacatc cggcacatcc
     8761 tggtcgataa gggcgagcag tacgacaagg acgccgccat tttcaaggtg gtccgtccgg
     8821 tcctgcgcaa cggcctgatc gccaatgccg atatggcact gtggcgccgc cagcgccgca
     8881 tgatggcccc gcatttcacc ccgcgcacgg tcagcgcctt cgcccggaac atgacggacg
     8941 agaccgtgca gatgctggag cgctgggaac cccgtaccgc cgccggtgac accctcgaca
     9001 tcaccgacga aataggccag ttggcgctcc ggatcgtgaa ccggtcgctc ttcagtgccg
     9061 atgtggggac cgccgcccag gccttcgagc gggccttcgg cgaggcgaac agtatcctcg
     9121 gcgccttctt ccgcttcccg ttccctccgc tcagcgtccc gacgcccagc caccggcggc
     9181 tgcgccgggc gatcaacggt atggacgcat tcgtctccgg cttcatcaag aagcggctga
     9241 acgacgaggt cgccacgggc gaggaaaccg atctgctgac ccttctgctg cactccgtgg
     9301 acgaggagga cggcaaggga atggacctgg agcaactgca ccacgaggtc ctgaacatct
     9361 gcatcggcgc ctacgaaacg accaccaaca ccctctcatg ggcgttctat ctgctggccc
     9421 ggcatcccga gatcgaggag cggctgcatg ccgaggtcga cgaggtgctg ggcggccggg
     9481 tcccggcctt cgaggatctg ccgaagctgg tgtacacccg catggtcgtc gaagagacgc
     9541 tgcgcatcta ttccccggcg tatcagttca tgcgccgggc gcgggaagag gacgagatcg
     9601 acggctatcg gatgccggcc ggcgccaatg tcctcatcaa cagctatttc ctgcaccggc
     9661 atccggactt ctgggaagag cccgaacgtt tcgtgcccga gcgtttcacc cccgagcagg
     9721 tcgcccagcg ccccaagcac gtctacatac cgttcggcag cggccaccgc atctgtatcg
     9781 gcaagcactt cgcgctgacc gaactcaccc tcgtgctggc caccgtggcc cggcaccacc
     9841 ggctggtcat gcccgaaggc gccgccgagg tgcacccgga ggccctgatc accctgcacc
     9901 ccaagggcgg agtgcacttg cggccggagc cccgcggatg aaccggaaca ccagacgcgg
     9961 tgcgcggacc gcggcaccag cgaaaacagc ggaggcaccc gtgccggaca ttttccaccc
    10021 ctttccctac cggatcagcc cgcatgtcgc ggaggcccgt gagcatctga cggactggac
    10081 acggcgcata gggctgatag agcgggaagc cgccagaaag cgcttcgcga aagccgactt
    10141 cggctggttc gcggcaatgg tgtatcccac cgccgacgcc acccggctga atctcatggc
    10201 ggactggttc gcctggctct ttctcgtcga cgaccagttg gacgacggaa gcatcgggcg
    10261 cagccccgaa cgggcacggg acatcgtgga cggaatgcgg gtggtactgg agagcccgga
    10321 tcacggggcg gcggccgcgg ccgaccggga cggcccggtg gcggtctccg cactcgccga
    10381 tctgtggctg cgtacggcac cgcacgccac cgcgcattgg cgccgccggt tcgtccagca
    10441 cctggacgac tgcctcaccg tggccgccac ctgggaggcc gggaaccggg tcacgggaac
    10501 ggtgccggac gaggagacct atatcgaaat gcgccggcac accggtgcga tctatgtctg
    10561 catggacttc atcgacatcg tcgaacgcat cgacatcccc gattccctct ataccggtgc
    10621 gcagttccag gctgctctcg acgccgcgtg caacgtcgtg tgctggacca acgacgtcta
    10681 ctcgctcgca aaggagcgcg cactgggcga ggtccacaat ctcgtccata tcgtcgagca
    10741 ccaccgagga ctcgacaccc ccggggcgct ggaccacgtc tgcgccgcca cctcgaccga
    10801 gaccacgctg ttcctcgaaa aggagcggga actcctggcg gcccgccccg agcaccacgc
    10861 ggtgctcgtc cccaccctcg cgggcatgcg gacctggatg cgaggaaatc ttgactggtc
    10921 caggagcacc aagcgctatc gccccgtgga aggcgacgag gaaatacggc cggaagagta
    10981 cctggaggcg agtctcatga aggtggacca gtgaccacga caggggagag accggcactc
    11041 gcgcagcccg gctctgccgg ccccggaaat gccgccgccc ccgggaattc cgcccccgac
    11101 gcctggcacc tcctcaaaac ggcccgggag ctgaccgaac ccgaactccg caaagccgtg
    11161 gaccgtctcg ccgaaccggt ccgctcggtg gccgcctacc acttcggctg gtcggacgag
    11221 tgcggccggc cggcgaacgg ggagggcgga aagggcgtac gcgcggccct ggtgctggcc
    11281 gcggcccagg ccctcgggac ggtggccgaa gaagcggtgg cgcccgccgc tgcggtggaa
    11341 ctcgtccaca acttctcggt ggtgcacgac gacctcatgg acggcgatct gctgcgccgg
    11401 ggccgtagta cggcgtggtc gcagttcggc tccacacagg cgattctggc gggtgacgcc
    11461 ctcctggccg tcgctgtcga caccctcgcc caccgatgcc ctcagggagg ccccgaggcc
    11521 gtacgggaac tctcggggtc cctgctcgca ctggtcgccg gccagggcgc cgatctcgcc
    11581 ttcgagaccc gggcggacgt cggcctggcc gaatgcctgg agatggcggc cggcaagacg
    11641 gcgtccctgc tcgccgcggc ctgcgcgctc ggcgcactcg cggcgcgtgc cggggccgaa
    11701 cgggtcgacg ccctgcggca attcggacgg cacctcgggc tcgccttcca gctcgtcgac
    11761 gacctgttgg gcatctgggg cgacaccgcc gtcaccggca agcccgtcgg ctcggacctc
    11821 cgctcgcgga agaagagcct gcccgtcgtc gcggccctgt ccagcggcac cccggccggc
    11881 gaccggctcg ccgcgctcta ccaccgtacg gagcccctgg acgacgccga gctgcgcacg
    11941 gccgcccggc tgatcgagga ggccggcggc aggcgctggg cccaggagga ggccgagcga
    12001 cagcggaccg cggcggtcac ccggctggcc accgccggcg tcaccccggg cggcacccgc
    12061 gcgctcaccg cgctcgccga cctgatcacc cgcagggacg tctgatccct cgcgggggca
    12121 cggagtagcg gccgggccgc tgggcacccg gccgagaccg cgcgcaaggg tgtgagagac
    12181 cccatcgagg cggcggagac ggcgtctgcg tccgtggtac gcgcggcagc ccccgtactg
    12241 cgttcgtggc aggtcaagag tctgcgggcg cacgatgaca gcggtggaac cccgcgctga
    12301 cggccctgag ccccgctccg gggttcccgc ccggctgccg cccccgcaag tcgttggtca
    12361 gagccagcgg cgccgtttga agatgaggta caagctggtg cagacgaccg ccatcaggac
    12421 gagggcgaag gggtagccga agacccagtg cagctccggc atctcgtcga agttcatgcc
    12481 gtagatcgtc ccgaccaggg tcggcgcgaa gaggatcgcc gcccacgccg agatcttctt
    12541 gacctcctcg ttctgctcga aaccggcctc ggccagggcg cgcatctcgg cgttctgctg
    12601 ctggttcacc agggtcgcgt tgacggtgag gatgtcctga agggcctgcc ggaagccgtc
    12661 cacccgctcc gtggtgtgca ggacgtggtc ggccacatcg cgcagatagc ggcgcagttc
    12721 ctcgtcgatg gcgtacttct cgaagcccgc ggtcaggctc tccagcatgc cgttcagcgg
    12781 gcgggtggcg cgctggaact cgaccacctc acgggagagt tcatagatac ggcgggaaac
    12841 ccgggggtcg ccgccgaaga cctcggtctc gatctcgtcg atatcggtct ggacaccgtc
    12901 gacgactggt gcgtagccgt cgacgaccgc gtcgaggatc gcgtagagga cggcttcggg
    12961 gccgcgcttg aggagttcgg gggtgtcctc catgcgccgg cgtacggccg agaggtcggg
    13021 ggcgccgccg tgccgcacgg tgatcacgaa gtcccggccg acgaagacgt gcagctcgcc
    13081 gaagtcgacc tcctcggggt cgtcgaggta gcgcgcggcg cgcagaacga cgaagagggt
    13141 gccgccgtag cgctccagct tgggccgctg gtgcgcctcc agggcgtctt cgatggcgag
    13201 cggatggagg tcgaactccg acgccagggt gaccagttcg gcggaggtgg ggcggtgcag
    13261 gccgatccag gcgagggtgc cggaggtggc gcgctgctgc cggaaggcgt cggcgagcgt
    13321 ctcatgggtg ctgacccggt gtccgtcgcg atagagggcg gcggtgatga tgctgctggg
    13381 ggtttcggcc ggcggttccg gcgcggcgga gccgtccgtg gtctcggcgg gcggcggtcc
    13441 cgcgggccgc ttcttcgcgg gtttgcgcag gccgcgcagt ccacgcggcc gacggccggg
    13501 aggctcagag ctcacgacag aacggacctc cgtcacaagg gggatgaacg ggcacacaga
    13561 atctcgacgc aggatatctg ccgaggatgt cagcacaggt cagcggccat ggtgcaggat
    13621 ggaaccggac gcgacgcggc gtgtgtcgcg tccgccgggc tttgtacgtc tatccctaga
    13681 attgtgcgat gcagataccg cagacagcca gcgctcccct gggtgaggtg attcggtgaa
    13741 cggccccgat gccaccgacg agcagtggga agggctcgcc gaggtcgtcc cgctccgcag
    13801 cagcagcgga tggccttcct ggcccgacca ccgtgccctc cccgaggagg agccggcgga
    13861 gcagctgcgg cggttcatcg tcatccgcgt ccagaccttc gcggacgccc gtgaggtcgc
    13921 cgagtacttg atggcgcaga tccccgtcct gctggacctc agcagcgccg acgccgacgt
    13981 cgccaagcgc atcctggact tctccagcgg agtcgtcttc gggctgggca gcgggatgca
    14041 ccgcgtcgac accaatgtct tcctgctggc gcccgttggt accgaggtcg cggaaacggc
    14101 actcgggggc gtcccccgtt cgtaggaaga gctgttgggc gtaacggttc tccggtcggg
    14161 gtgctgcata gcgtcccggc atgaataccg agactgtgcg gccggcggtc accgaattac
    14221 ggctgtccgc cttcaaaacc catcgcggcg tcaccctgcc gctcacccgg ctgacgctgc
    14281 tgagcggtga gagcggaagc ggcaagtcca gtgcgctgca ggcgtacgag atcctcgccc
    14341 ggctcggcag tggtgagtcg ctggcccggg ccgtggggga ggtggcgggc agcccggcgg
    14401 cgtgtgtgcc ggccggggcg cgccccgacg cacaggggcg gcgggggttc cggatcggct
    14461 gcacggtcga cggtccggcc ggccccgtca gcctcgatct cgccgtccag gccgagcccg
    14521 aactccgcat cgtcggcgag cggttgaccg ggggcggcga gaccttgctg accaccgcgc
    14581 tcaccgaccc ggaccgcccc accgtccagg cggcctggca caccgcgggg gcgactccgg
    14641 tgacccgcgc cccgttgccc gacgaccggc tcggcacctc actcctgccg ttgcgtgtcg
    14701 cgggcaagac ggcggggcag cgcctggtcc tcgcggcggc cgaacaggtc gtggtcgcgc
    14761 tgcggtcggc gttcgtgtgc gacccgcggc cggaggtcat gcggggagcg gggacgggcg
    14821 ggacggggga gccgggccgg acggtgcgtg tggtgcggac ggcgccggtg gtgccagtgg
    14881 cgccagtggt gccggaggtg gcgtcggggt acggcggagt ggccgggaag cgggcttgcg
    14941 gggcggggcg gggaagccgg gcggggccgg tggggctgcc ggggcctggg ggccgcggaa
    15001 gcgtacgggc agtggtggtg aggcgggcgg ctgggcccgc gatacggagg gcgcgcgggc
    15061 cgaggggcgg ctgcggtcgt cctgcgacaa cctgcccgcg gtgctggagc ggaccagcca
    15121 ggagtgtgcg cgacggcatg cggtgctggt cgcggcggta cgggaggctt gcgccggtcc
    15181 cgtcgagggg ctgcgtgcgg tgccgtggca ggcgggcggt acgggggagt cgcccgccga
    15241 cgccgctgcg ccggccgggc cggtgggcac cgcggggccg cgggccgggg tggcgggcgt
    15301 gcgggcggtc ctcgaccggg gggagctggg tgagctgccc gtcgagcagc tcggcgacgg
    15361 tgagctgcgg tttctcgcgc tggcgctggt gctgctcacc gggccggagg tgctggccat
    15421 ggatccggtc ggggaggtgc cgtctgccca tcagcagatg acggtgatgg cggacgggat
    15481 ggaccgctgt atggacgcca ggcaggcgcg cgagctggtg tcgctggccc tgcggatgac
    15541 cgaccgcggg catgtgcggc tgctggggac ggtgcgggat ccctcggtcg ccgaggggct
    15601 gcccggcgta caggtgctac acctaggggt atgagcgagg atcttcatgc gttgcagcga
    15661 cggctggccg aattcgcggc cgcgcgggat tggcagcagt accacacgcc caagaacctg
    15721 gccgcggcgc tgagcgtcga ggccgcggaa ctcgtcgaga tcttccagtg gttgacgccg
    15781 gaggagtcgg cgaaggtgat gacgaacccg gggaaggccg gccgggtcga ggacgaggtc
    15841 gcggacgtgc tggcgtatct gctccagttc tgcgaggcgc tggggatcga cgccctggcg
    15901 gcgctcgccg cgaagatcga gcgcaatgag tcgcgcttcc cggcggtccg ctcggcgcgc
    15961 ccggaccggc cgcgggaggg cgaggagtag ggcggggacg gagctaaggg cgcgggggag
    16021 cgaagaacgc gggggtgcag gggcggggcc ggcggggtgt gaacgccggc cccgcccctg
    16081 gtgtgttgtc cgtggtgccg tgtgctgttc gcccggtggt ccggtccgtg ttcgcttcgg
    16141 cggtttcgcg tgacttgtgc cggtggtgtg aggggtgggg gtgctggggc ggaaggggag
    16201 ggagcggggg tacgacagcc gcttgtcact ctccggagtc atggatcttt ccgcatcgcc
    16261 tcgcttgtcc acagatctgc gaattcccct ggcttttttg ggtgttcgca ttcactctgg
    16321 gtagtggaaa gagtgcaggg cgcatgcgaa tgaagaggag aggaggggag cggatggacg
    16381 cggtgcggat catcgcggcc agtcgacgcg ggctggcaga ggcgaacacg gttcagggag
    16441 tgatcgtcga ggcatggcag gcgcaggcct tggcggaggc ggtcggcagc catctcgcga
    16501 tattcgggcc gtatgaagtg cggtccaggg cccggggatt gggcgacgca ggcgggcggt
    16561 tcagcggggg actgctgtgc ccggcgtcgg tcaccggcgg tgggctgcgg gcggctcagc
    16621 tgtccgaggt gcgtgatgcc aaggcggctt taaccggcct gtgcctcctg ctgcgagagg
    16681 tgtgcgaagc gctggtggcg gtggtgctgc tggcggacga ggacgggatg tactggacct
    16741 gcgtcgaggc gatggacacg gtcgatgaat cgagagaccg cgtcgccgga atactggaga
    16801 aattggaggt gcgcgaccgg aaccccgcct gagcaccaca ccaccgcacg accgtgccaa
    16861 ccctgcgctc gccccgtcgc atgtctcgcg ccattcatgg tcaggccccg cccaccgccg
    16921 gccgtgtcca tccccatgcc acccgtaccc agtccgcccc gctgcgccga agcgctctcc
    16981 gacggttggg gggtcgtgcg gcgtgcagga tggaggtatg gacctacgaa tcttcaccga
    17041 gccgcagcag ggtgcctcct acgagactct gctgaaggtc gccaaagcta ctgaggatct
    17101 tggtttcgac gcgttcttcc gctcggacca ctatctccgg atgggcaatg ccgacgggct
    17161 gcccggcccg accgatgcct ggatcacgct ggccggcctc gctcgtgaga cccggcgcat
    17221 ccgtctcggc acgctcatga cggccggcac cttccggctg ccgggtgcgc tcgccatcca
    17281 ggtcgcccag gtcgaccaga tgtcgggcgg ccgggtcgaa ctcggcctcg gggcgggctg
    17341 gttcgaggag gagcacaagg cgtacggcat tccgttcccc aaggagaagt tcggacggct
    17401 ggaagagcag ctggcgatca tcaccggcct gtggggcacc gcaacaggag aggagttcag
    17461 ctacgacggg acctactacc agctggagaa ttcgcccgcg ctgcccaagc ccgcccaggg
    17521 caaggtgccg gtgctggtcg gcggccacgg tgcgacgcgt acaccgcggc tggcggcgca
    17581 gtacgccgat gagttcaata tccccttcgc ctcgctcgaa gacagcgcgc gccagttcgg
    17641 acgggtgcgg gcggccgccg aggccgccgg gcggaagggc gaggagctgg tgtactccaa
    17701 cgccctcgtg gcctgcgtcg ggagggacga cgccgaggtg gcgcgacggg ccgcggccat
    17761 cgggcgcgag gtggacgaac tgaaggccaa cggcctggcg ggctcgcccg ccgaggtcgt
    17821 cgacaagatc ggccgttatg ccgcgatcgg cgcgtcccgg gtctacctgc agatgctgga
    17881 cctggacgat ctggaccacc tggagctgat ctcgacgcag gtgcagtcgc agctgaactg
    17941 acgccgggcg gggcggcgct gtcgtggaaa accggtgggg ccggggctgt cttgcggcaa
    18001 tactcggacg cgtgttcctg acgataacca ccaccggcag cgccgaccgt cccgcgaccg
    18061 acctcggctt tctgctgcac aagcatcccg acaaggcgca gcggttctcg acgtcgcagg
    18121 gcaccgcgca tgtcttgtat ccggacgccg acgcacaacg gtgcaccgcc gcactgctgc
    18181 tggaggtcga tcccatcgcc ctggtgcgca agagccgcgg caagggccgg ggcggtgcgc
    18241 cggattcggc gctcggccag tatgtgaacg accgcccgta cgcggcctcc tcgctgttgg
    18301 cggtggcgct gcggaccgtc ttcgccagcg cgatgaaggg gcagtgcacg gcacggcccg
    18361 agctggtggc gcaggcgctg ccgttgcgta tcgaggtgcc ggtgctgccc gcccggggtg
    18421 gcccggagct ggtggacaag ctgttccggc cgctgggctg gacggtgcgg gccgagccgg
    18481 taccgctgga cgagacgttc ccggagtggg gtgactcgcg ctatgtacgg ctcgtcctgg
    18541 aaggggagtg ccggctgtcc gaggcgctgc ggcatctgta tgtgctgctg ccggtgctgg
    18601 acgacgccaa gcactactgg gtcgcgcccg acgaggtcga caagctgctg cgggccggcg
    18661 agggctggct ggagggccat ccggagcagc gggtgatcgt cggccgctat ctcgcgcggc
    18721 gctggtcgct gacgcgccag gccatggagc gactggaact ggtgcggctg gccgagtcgg
    18781 acgacgtggc cgccgaggag ctcgacaacg ccgtggacga ggaggcggac accgaggaga
    18841 agccggtgcc gctcgctgtc cggcggcggg aggcgatcct cgcggttctg cgctcggccg
    18901 gggcggcgcg ggtgctcgac ctgggctgcg gtccgggcca gctggtcggt gagctgctca
    18961 aggagggcca gttcaccgag atcgtcggcg tggatgtgtc gatgcgggcg ctgcacgagg
    19021 cgcggcgccg gctgcggctg gaccggatgt cggagcggca gtcggcgcgc gtacggctcg
    19081 tacaggggtc gctggcgtac accgacggcc ggctgaaggg gtatgacgcg gcggtgctca
    19141 gcgaggtcgt cgagcatgtc gacccggcgc ggctgccggc gctggagtac gcggtgttcg
    19201 ggtcggccag gccgggcacg gtcgtggtga cgacgccgaa tgtcgagtac aacgtgcgct
    19261 gggagtcgct gccggccggc cgggtgcggc atgcggacca ccgcttcgag tggacccggg
    19321 aggagttccg gcagtgggcg cacggggtcg ccgcccggca cggctacgag gtgagcttcg
    19381 gcccggtggg cccggacgac cccgaggtcg gcccgcccac ccagctcgcg cacttccgca
    19441 gggccggtga cgacagcagc ggcccggcag acagtgcgaa cagccggcaa ggccgagacc
    19501 ctgaaggcag tgggaacggc agggaaggcc gcggccccga aggcggcagc cgggaggacc
    19561 ggcagtccga agacagcggg agcgtccggg aaaaccgggc gcctgaaggt ggcagcagcg
    19621 ctgcgggcgg cagcggctcg atgaggggga aggaggtcgc ggcatgacgg acgacgaccg
    19681 tagcgagtac ggcgagaaga acgagcaccc gcacgaggac cagcaggaga gcgggagcgc
    19741 gcaggacagc ggtccccgcc aggacagcgc ggagcagccg ccgcggcccc ggcccgagcg
    19801 ggcgccgcgt acgctcgccg tgcccgacct ctccctcgtg gtgctgatcg gagccaccgg
    19861 ctccggcaag tccaccttcg ccgcccggca cttccggccg accgaggtcc tctcctccga
    19921 cttctgccgg gggctggtca gcgacgacga gaacgaccag agcgccagcg gtgacgcctt
    19981 cgacgtcctg cacttcatcg cgggcaagcg gctggccgcc gggcggctga cggtcgtgga
    20041 cgccaccaat gtgcagtccg aggcgcgtac ccagctggtg cggctggccc gggagcatga
    20101 cgtcctcccg gtggcgatcg tgctggacat gcccgagcag gtctgcgccg cacgcaacgc
    20161 ggcgcgcgcc gaccgggccg ggctgccccg ccgggtcatc cagcgccacc agcgcgaact
    20221 ccgccgttcc ctgcgccact tggagcggga gggcttccgc aaggtgcaca tcctgcgcgg
    20281 cccggaggag gtggagtcgg ccgaggtcgt caccgagcgg cgattcaacg atctgcgcca
    20341 tctcgccggt ccgttcgaca tcatcggcga tatccacggc tgccgttccg agctggagac
    20401 cctgctcggc aggctgggct atgcgctggt gcgcgacacg ctcggccggc cggtggacgc
    20461 ggtgcacccc gagggccgta cggcggtctt cgtcggtgac ctcgtcgacc gcgggccgga
    20521 cagccccggc gtgctgcgac tggtgatggg catggtcggg gccgggcacg cgctgtgtgt
    20581 gccgggcaac cacgagaaca agctcggccg ctacctcaag ggcagcaagg tccagcacac
    20641 ccacgggctc gccgagacca tcgagcagct ggagaaggag gacgccgcct tccgtaccga
    20701 ggtcggggag ttcatccgcg gcctggtcag ccactacgtc ctggacgggg gcggcctcgt
    20761 ggtgtgccac gccgggctgc cggagaagta ccacggccgg acctcggggc gggtgcgctc
    20821 cttcgcgctg tacggggaca cgaccggcga gaccgacgag ttcggcctgc cggtgcgcta
    20881 cccgtgggcc gaggactacc gcggccgcgc cgccgtcgtc tacggccaca cccccacccc
    20941 gcgcgccacc tggctcaaca acaccctctg cctggacacc ggctgtgtct tcggcggggc
    21001 gatgaccgcg ctgcggtggc ccgagcgcga gctggtggac gtaccggccg agcgggtctg
    21061 gtacgagccc acgaagccgc tggcgtcgga ggcgcccggc ggggcggacg gccgtccgct
    21121 cgatctgaac gatgtggccg ggcggcggat cgtggagacc cggtacatgg gccgcctcgc
    21181 ggtcaaggag gagaacgccg cggccgcgct ggaggtgatg agccgcttcg cgatcgaccc
    21241 gcggctgctg ccgtacctcc cgcccacgat ggcgccctgc gcgacctcgt cggaggaggg
    21301 gtacctggag caccccgcgg aggcgttcgc cggctaccgg gccgacggcg tacgggaagt
    21361 ggtgtgcgag gagaagcaca tggggtcccg cgcggtggcg ctggtgtgcc gcgacgagac
    21421 cgtggccggt aaacgcttcg gcgtgcccaa gggcgtgccg ggcgcgctgt acacccgtac
    21481 cggccggccg ttcttcgacg acccggaggc gaccgaacgc ctgctgcggc gggtccggga
    21541 ctgcgccgag gaggccggtc tgtgggacga gctggagacc gactggcttc tcttggacgc
    21601 cgagctgatg ccctggtccc tgaaggcgac cggtctgctg cgcaagcagt acgcggcggt
    21661 gggcgcggcg tccggggcgg cgttcccggg cgtgctcggt gcgctggacg cggcggccgc
    21721 ccgcggagtc gaggtggcac cgttgcgcgg ccgtcagcag gaccgggcgg cggacgcggc
    21781 cgcgttcacc gaggcgtacc ggcgctactg ctggcgcgtc ggggcgacgg cggcggacgg
    21841 cgaggagccg ccggagccgc aggagccgga gcggcggcgc cgggctgggg agctggacgg
    21901 tgtgcggctc gcaccgttcc agatcctcgc ggtgcggggc cgcagcctcg ccgggctggc
    21961 gcacaccgag cagctcgccc tgctcgaccg gctgatcgcg gccgagggcg cggtggcggc
    22021 ccgggagggc gggacggccg gcggcgtcac ggaccggccg gggctgctcg ccacgacccg
    22081 gcggatcctg gtcgacaccg aggac
//
