LOCUS       NZ_CP050976            21047 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5672207
            Orig. end                         :: 5693254
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21047
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="20"
                     /rules="atropopeptide_p450"
                     /tool="antismash"
     cand_cluster    1..21047
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21047
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11047](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11047)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            213..1139
                     /locus_tag="HEP86_RS25415"
                     /old_locus_tag="HEP86_25415"
     CDS             213..1139
                     /GO_process="GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089174.1"
                     /locus_tag="HEP86_RS25415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25415"
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="WP_168481087.1"
                     /transl_table=11
                     /translation="MSTNSRLRNLGNREAGPGRPVYVTGEIGINHNGDLENAFALIDAA
                     ADAGCDAVKFQKRTPEVCTPRDQWEIERDTPWGRMTYIDYRHRVEFDEDGYRAIDEYCK
                     KRGIAWFASPWDVESVAFLEKFDVPCYKVASASLTDDELLRAMRATGRTVILSTGMSTP
                     KQIRHAVEVLGSENILLCHATSTYPAKAEELNLRMINTLQDEYPNVPIGYSGHETGLQT
                     TLAAVALGATFVERHITLDRAMWGSDQAASVEPGGLTRLVRDIRTIEESLGDGVKKVYE
                     SELGPMKKLRRVTGVVAEAEAAEPAAV"
     gene            1360..2379
                     /locus_tag="HEP86_RS25420"
                     /old_locus_tag="HEP86_25420"
     CDS             1360..2379
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089175.1"
                     /locus_tag="HEP86_RS25420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25420"
                     /product="hypothetical protein"
                     /protein_id="WP_168483961.1"
                     /transl_table=11
                     /translation="MQLLNVLEWAHTAQATGLTVVVLSPHDPMTRGQLRRMAELARDEG
                     HTVRWEEARGGPTAPMRTIGGLTPLLRRARRVVIGDPFSRYVQLLLSLARARDLVVVDD
                     GTATMEFISQLARGEKLVRWHRSGSGRGARDLIFAPFSATARRRLTPAPEGGRRTVGLF
                     SSMPVEAPPGVEVTTNEFAWTRGRFGPPRLTRAADIVGTSLVETGVVDTERYLAAVGSL
                     ARTHGATRYFAHRKESTEKLRRLVVETGLEIVRPDLPLELIARRGPIGRLIVSFPSTVV
                     HTLPLALRGTEVKVAVCDIDPEWLTANASPRAQGFLDGVTGTARDVQRLPFTQPMAAG"
     misc_feature    2399..2415
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     gene            2518..3789
                     /locus_tag="HEP86_RS25425"
                     /old_locus_tag="HEP86_25425"
     CDS             2518..3789
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089176.1"
                     /locus_tag="HEP86_RS25425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25425"
                     /product="amidohydrolase"
                     /protein_id="WP_168481088.1"
                     /transl_table=11
                     /translation="MNHVKSREVSAARTPAGDQLPGALPEALRAELSAFRRDLHRHPEL
                     GNQEFRTTAAIKERLERAGLRPRVLATGTGLICDIGTRDAMADGQAAATAPDRPLLALR
                     ADIDALPIPDTKNVDYASTVAGRAHACGHDVHTVVVLGAGLVLAELARTGALPRPVRLL
                     FQPAEEVLPGGAPDAIESGALEGVGRILAVHCDPRVDAGRIGLRTGAITSACDRLEVEL
                     DGPGGHTARPHLTTDMVTAASRVAVDVPALLARRVDARAGLAVTWGRLASGHACNVIPE
                     HAELSGTVRCLDLDAWRQAPDLVHAAIDEVAALHGAKSQITYVRGVPPVVNEPVTVQLL
                     HSAMAARRGEGAIEDTEQSLGGEDFSWYLEHVPGAMARLGVHPPADPTYRDLHRGDFDV
                     DEQAIKVGVELFTGAALLDGDLAD"
     gene            4037..5068
                     /locus_tag="HEP86_RS25430"
                     /old_locus_tag="HEP86_25430"
     CDS             4037..5068
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986626.1"
                     /locus_tag="HEP86_RS25430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25430"
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_168481089.1"
                     /transl_table=11
                     /translation="MRRVIRIAAAATATAGLALTATACGQSFAEANRAKHAGVGVAFDI
                     GGRDDHSFNEAAARGADNATKKLGVNAKMLTAKNGETEADREQRLTSFAEAGYNPVIGV
                     GFAYSQAVQNVAKDFPATTFGVVDAVPEGKNVDAMVFAEHEGSYLAGVAAALKSKNHKV
                     GFIGGVNNALIQKFQAGFEQGVRDTDPKTKVTSQYLYPNNDKGFNDPAAAKAKAGGMLD
                     SGIDVIYTAAGQSGAGTIEAISKVKGAWAIGVDSDQYQQPGLARYKNRILTSVVKNVDV
                     AVFDLIKSAEDGKPLTGIHSYDLKHSGVSLATSGGFIKDIQPQIDAARKKIIEGKVKVK
                     ETP"
     gene            5287..6843
                     /locus_tag="HEP86_RS25435"
                     /old_locus_tag="HEP86_25435"
     CDS             5287..6843
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089184.1"
                     /locus_tag="HEP86_RS25435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25435"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_211117412.1"
                     /transl_table=11
                     /translation="MANHDIHLTVRRGTVHALCGENGAGKSTLMKILYGMQKPDEGTIA
                     LGGEQVTLHTPGDAIARGIGMVHQHFMLADNLTVLENTVLGAEKLHGIGAGARAKIKEL
                     SDAYGLNIRPDVLVEDLGVADRQRVEILKVLYRGARTLILDEPTAVLVPQEVDALFDNL
                     RELKSEGLTVIFISHKLGEVLSVADDITVIRRGTTVASVEPSGTTPKQLAELMVGSELP
                     SPETRESTVTDEEMLRVSDVHLSATDSDGVVRTVLDGISFTIHKGEVLGVAGVEGNGQA
                     ELVEAVMGTRRPDHGTITLDGTDLSGASTRARREGGIGYIPEDRHRHGLLLEAPLWENR
                     ILGHVTERPNSKGKLLDIPGARKDTERIVEQYDVRTPGIEVTASSLSGGNQQKLIVGRE
                     MSHHPKLLIAAHPTRGVDVGAQAQIWEQIREARREGLAVLLISADLDELIGLSDTLRVM
                     YRGRLVADADPAVITPEELGSAMTGAARGHLSASEDGAPDDGAPADGASQDAGEQEGDE
                     Q"
     gene            6867..8009
                     /locus_tag="HEP86_RS25440"
                     /old_locus_tag="HEP86_25440"
     CDS             6867..8009
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574956.1"
                     /locus_tag="HEP86_RS25440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25440"
                     /product="ABC transporter permease"
                     /protein_id="WP_168483963.1"
                     /transl_table=11
                     /translation="MDAIAKSATRDKVILAIAAPVLAIVAAIVISSLVFLASGENPFRA
                     YGIMADYGHYSDSQVWIINKAVPYYLSALAVAIGFRMNLFNIGVDGQYRLAAFAAAAVG
                     GAIALPGALQIILLIVIAMLVGALWSGIAGLLKTTRGVSEVITTIMLNAIAASIIGYFL
                     QDGRLAIKDGNLLHTKFLPESSHFFTFPTHPKPVLGFVVIAILAGALYWFGINRTRFGF
                     DLRAVGASEPAAEASGVSVKRMVLCSMLLSGAAAGLVGMPTLLGESFQYGTDFPAGIGF
                     TGIAIALLGRNHPVGMAFGALLWAFLDRTGSRLEFEGYAQEIVGVMQGVIVLCVVIAYE
                     IVRRYGLSLQQRKVGEELAALSRTNNTDKSDKSDNPEVSA"
     gene            8006..9286
                     /locus_tag="HEP86_RS25445"
                     /old_locus_tag="HEP86_25445"
     CDS             8006..9286
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089186.1"
                     /locus_tag="HEP86_RS25445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25445"
                     /product="ABC transporter permease"
                     /protein_id="WP_168481090.1"
                     /transl_table=11
                     /translation="MSTDLKTATKLAVPGKGGRRKLTYPWILLIIAVGLVAVSVLRAFT
                     GAGDLTSTGQFGAALSAAVPIGLAGLGGLWSERAGVVNIGLEGMMMLGSFAAGWVGWQH
                     GPWAAAAAGILGGALGGLIHAIATVTFGVDHIVSGVAVNILALGATQYLATLWFGQEGS
                     AAMLAGGNDKQSPPMPDMPTFTVPGLSDALNTLEGHHWFLVSDVAGILGAAVTNVSWLT
                     LLTIGLFIGTFFVLWRSSFGLRLRSCGEAPISAETLGVNVYSYKYAAVLVSGALAGLGG
                     AFLSIGVHFFQDGQTGGRGYIGLATMIFGNWRPGGVAMGAGLFGFMDAMQLRSGGPTVH
                     ALLLGLAALLAVLALLRLRAAKRTQGVVAGIAAAVLVIWYFLADTVPLELVEASPYIAT
                     LLVLALFSQRLRPPKANGKPYRRGQGT"
     gene            9283..9702
                     /locus_tag="HEP86_RS25450"
                     /old_locus_tag="HEP86_25450"
     CDS             9283..9702
                     /EC_number="3.5.4.5"
                     /GO_function="GO:0004126 - cytidine deaminase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397723.1"
                     /locus_tag="HEP86_RS25450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25450"
                     /product="cytidine deaminase"
                     /protein_id="WP_168481091.1"
                     /transl_table=11
                     /translation="MTPPVPVDWTALRAQARDAMSRAYAPYSGYPVGAAALVDDGRTIT
                     GCNVENASYGLALCAECGLISELFAGRPDNDGPTPRLTAFTCVDGTGALLVPCGRCRQL
                     LWEHGGPDLLVDTMAGIRPLSELLPDAFGAGHLRG"
     gene            complement(<9786..>9962)
                     /locus_tag="HEP86_RS40840"
                     /old_locus_tag="HEP86_25455"
                     /pseudo=""
     CDS             complement(<9786..9962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104988.1"
                     /locus_tag="HEP86_RS40840"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HEP86_25455"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLYARGLGRARELGAEVIETVVLSSNEDGLRFARKHGFVETERYL
                     LPGDSIPWIDLRLA"
     gene            complement(10001..11047)
                     /locus_tag="HEP86_RS25460"
                     /old_locus_tag="HEP86_25460"
     CDS             complement(10001..11047)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000173: Biaryl bond formation (60% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089189.1"
                     /locus_tag="HEP86_RS25460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25460"
                     /product="cytochrome P450"
                     /protein_id="WP_168481092.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 8e-185,
                     bitscore: 612.6, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 1.1e-12, bitscore: 46.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPMHRVGESGRVIEFAPRIDELLSRYRGASLFRLEPDTIGVSGAE
                     LMDRLLRSRPANAEERPTFKPVQGRLVSRTDASTFMQAVGSDVRNALQRPLDEAVDLTG
                     RWPHVAHVYLRNLVFGNERLRFRVLVDRRLELTPKLTWSAVASGAALLGRPGQDVPLSK
                     LAALVLDSTTYGDRRYAMYLYRRVAAPVCFTVSALVTNALWLGAPFSDDVSNRNILLEA
                     LRLLPPSWNILRMASPEFSDVDARIGPKDDVLLLPLLSHRDPELWDEPDAFHPSRWEEL
                     DGDNHPGYLPFGHVSERCWGRHMVLPLAERLLDIVRRDGLVVNPGQTRGKVELDGLLEV
                     SEVQMTRP"
     misc_feature    complement(10898..10900)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10979..10981)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11185..11203
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.76"
                     /tool="antismash"
     misc_feature    complement(11187..11201)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            11530..11850
                     /gene="cutA"
                     /locus_tag="HEP86_RS25465"
                     /old_locus_tag="HEP86_25465"
     CDS             11530..11850
                     /GO_process="GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522485.1"
                     /locus_tag="HEP86_RS25465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25465"
                     /product="divalent-cation tolerance protein CutA"
                     /protein_id="WP_168483964.1"
                     /transl_table=11
                     /translation="MLRRGGSPARKSGEAAVKLAQSVVSARLAAGAQIVGPVGSVFWHQ
                     GEFGSGEEWQLVLKIRADRYDEVEAHLLKHHPWQNPEVSAVPIVAGANGYLRWLETTTA
                     PD"
     gene            complement(11931..12398)
                     /locus_tag="HEP86_RS25470"
                     /old_locus_tag="HEP86_25470"
     CDS             complement(11931..12398)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603586.1"
                     /locus_tag="HEP86_RS25470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25470"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_168481093.1"
                     /transl_table=11
                     /translation="MSRRDYENDPHAPAANSLVPAASAVVIDDSGRVLLQRRRDNGMWA
                     LPGGVMNIGESLPDCAVRETREETGFHVEVVGIVGTYTNPHHVFAYDDGEVRQEFSICF
                     LARPLGGQLAVSGESTDVRWFEPGEIDALPMVPSIRKRLNDWRDGNMPATR"
     misc_feature    12430..12445
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            12650..13879
                     /locus_tag="HEP86_RS25475"
                     /old_locus_tag="HEP86_25475"
     CDS             12650..13879
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089193.1"
                     /locus_tag="HEP86_RS25475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25475"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_168481094.1"
                     /transl_table=11
                     /translation="MDLSDELGTGERIRVLRESRGMTRGALAHLCGRGTDWLKKIETGE
                     RELRSHTLLLRLGAALQVSDLSVLTGDSDGPAQLVPLGRLNHPAMPEIWTAVMNRSLTT
                     AATGPLEPAVLQGRVDQTWRLWHTTDRNRTEVGALLPGLIRDGEAAVRALDGDQRRAAL
                     VALSDVYRLTGQATAYVAPAELAWVVADRALSAAQDADQPAAIAAAAWNMGNILRETSY
                     PEEALRIVAEAADLIRPHLDDAPDDWRGIYGALQLHAAVTVAREGREGDAWRYWDKGDQ
                     VAKSLPASYVHPSTVFGRANVDFHAVSVATDLRKAQKALGLADDLDPDVMPSRERRARL
                     WVEVARGHRQRGDRTAALHVMQMAHRIGAETVTYTPSARVVAADLWRSAPRAMRKDAGR
                     LAEAVGVATA"
     gene            14002..14220
                     /locus_tag="HEP86_RS25480"
                     /old_locus_tag="HEP86_25480"
     CDS             14002..14220
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS25480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_25480"
                     /product="hypothetical protein"
                     /protein_id="WP_168481095.1"
                     /transl_table=11
                     /translation="MHASTRRGEPPSADGVTGEIRVPLALYAVDEHRGSVDLVLSRADT
                     ASLLASLVEALGAPTHASRPQRPEDAR"
     gene            14217..14657
                     /locus_tag="HEP86_RS25485"
                     /old_locus_tag="HEP86_25485"
     CDS             14217..14657
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089195.1"
                     /locus_tag="HEP86_RS25485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25485"
                     /product="hypothetical protein"
                     /protein_id="WP_168481096.1"
                     /transl_table=11
                     /translation="MINQSGLGKARTPQALSDNKDPRDVAASGGVAINPWEVDDMAKTI
                     ARIFESLLRLLLPARGRHRSFGCMPTVTCEDAPTLVFARVPGGREGLLRGEDAALIRPY
                     ALTPEERQKRRLEYGRRRVQLFAAYGTDAAPRWLNGLEAAGR"
     misc_feature    14382..14384
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14654..15019
                     /locus_tag="HEP86_RS25490"
                     /old_locus_tag="HEP86_25490"
     CDS             14654..15019
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089196.1"
                     /locus_tag="HEP86_RS25490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25490"
                     /product="hypothetical protein"
                     /protein_id="WP_168481097.1"
                     /transl_table=11
                     /translation="MSPTDTPRLLPWSSTDGKPCFLVGSGTGYVSRLADEMEEAQLDSA
                     AELGEEAHRILAGRAWTPGEIHLLALELAASLADVRRVAESRGARLPVPDDDGSDGDDA
                     PDDEGGDRPRLPAEAFG"
     gene            15330..16607
                     /locus_tag="HEP86_RS25495"
                     /old_locus_tag="HEP86_25495"
     CDS             15330..16607
                     /EC_number="2.4.2.4"
                     /GO_process="GO:0006206 - pyrimidine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578471.1"
                     /locus_tag="HEP86_RS25495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25495"
                     /product="thymidine phosphorylase"
                     /protein_id="WP_168481098.1"
                     /transl_table=11
                     /translation="MDAISVIRTKRDRGELTPDQIDWVIDAYTRGEVAHEQMSSLAMAI
                     FLNGMNRTEIARWTAAMINSGERMDFSSLPRPTADKHSTGGVGDKITLPLAPLVAACGA
                     AVPQLSGRGLGHTGGTLDKLEAIPGWRASLSNAEMLDVLRDVGSVICAAGDGLAPADKK
                     LYALRDVTGTVESIPLIASSIMSKKIAEGTGSLVLDVKVGSGAFMKDLDNARELASTMV
                     ELGADHGVRTVALLTDMATPLGLTAGNALEVRESVEVLAGGGPQDVVELTLALAREMLD
                     AAGLKDADPAKALADGSAMDHWRRMIAAQGGDPDAALPVAREQHVVTAASSGTLTTLDA
                     YAVGLAAWRLGAGRARREDPVQAGAGVELHAKPGDTVAAGQPLLTLHTDTPEKFAYALE
                     ALDGGVLIGPEDAAFATTPVVLERIA"
     gene            16735..17328
                     /locus_tag="HEP86_RS25500"
                     /old_locus_tag="HEP86_25500"
     CDS             16735..17328
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458896.1"
                     /locus_tag="HEP86_RS25500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25500"
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_211117414.1"
                     /transl_table=11
                     /translation="MIALTAEHFPEEGRVWDALVRIWEDTEAPEACMVEIVDGIVTVAP
                     PRDVRQNVIVAELSRALYQQALPENRGAYQKLALAVPARKGLYVPNLVVAPDSVVRGPG
                     RFIPAAAAELVVEITSMTSAVHDRLHKPAGYASAGVPLYLLIDLWSPDGPTATLHGEPD
                     HTRYRNQRSARLGERLHLPEPFDMTIDTSLFRVS"
     gene            complement(17395..18711)
                     /locus_tag="HEP86_RS25505"
                     /old_locus_tag="HEP86_25505"
     CDS             complement(17395..18711)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603575.1"
                     /locus_tag="HEP86_RS25505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25505"
                     /product="MFS transporter"
                     /protein_id="WP_168481099.1"
                     /transl_table=11
                     /translation="MPPADTGASVIDRAAASPQSSPDSSPAAAPDPEAGKLRPGGPGYR
                     RMSFALFAAGVATFALLYSTQALLPAISADLGVSPDQASWTVSAATFGLALGVIPLSAV
                     SERFGRRTLMMWSLAVAALLAMLVPFAPSLGALIALRGLQGVALAGLPASAMAFLAEEV
                     RAKALVAAIGLFVAGNSIGGMSGRIVTGWVAQAWGWRAALAAVGVLAVVCAVAFRLLVP
                     KARHFVSRSVGPRALARTLGSHLADPLLRRLYAIGGLFMTVFGAVYTVIGYRLVSEPFN
                     LPQGIVGSIFVVYLVGTVSSAAAGKLVARVGRRGALYLAVGTTSTGLLLTLSDSVGAVL
                     AGLILITAGFFAGHAVASSSVSRTAKTARAQASALYQCAYYVGSSLGGALGAAAFHAVG
                     WEGTVLLGLAAMLGAASITLYATRKAVAERRLLHLEKAA"
     gene            18807..19790
                     /locus_tag="HEP86_RS25510"
                     /old_locus_tag="HEP86_25510"
     CDS             18807..19790
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603574.1"
                     /locus_tag="HEP86_RS25510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25510"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_248001299.1"
                     /transl_table=11
                     /translation="MQGRNRKDIADSGRAGADAGEVAELGADSWAVTLAPRLAQFTAVA
                     RHEHVTRAAQELGMPQPTLSRAIVRLEEDLGVALFARHGRTLSLTPAGRAFLAATERAL
                     TDLERATESVRADVDPAAGKVAFGFLHTLGPETVPGLIRSFRADHPRVRFQLVQTYGEA
                     MIERLRAGDLDLCLTSPVPDYPDLVARRLDEQKLRLVVPDDHPLAARKRIRLAEAAGEL
                     FVTLEPGYGLRRITDALCAEAGFTPRVAFEGEEAETLRGLVAAGLGVALLPPPPVPRPG
                     VAELTVTAPRAVREIGVAWLDGHPDTPPVAEFKKFLLSRRGRLLPR"
     gene            complement(19903..20718)
                     /locus_tag="HEP86_RS25515"
                     /old_locus_tag="HEP86_25515"
     CDS             complement(19903..20718)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004984118.1"
                     /locus_tag="HEP86_RS25515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_25515"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_168481100.1"
                     /transl_table=11
                     /translation="MAQQALPVREARLGKPLGTAGKEGAREALRWKGGRRGTGREVSGV
                     ALLLPGGGPTGVRRPSPVAALAVRPLAVRLAKAGRPEGLTAHVVRYRCHGWNGAAAHPA
                     RDAQWALEEVVRRYGDVPVCLVGTGMGARAALHAAGHPAVNSVLAIAPWLPDPHRDSEH
                     PDPVKQLIGRQVLLVHGTNDERTDPDLSYRYAERAKKVNRDICRFEVHSDGHSLHQHRA
                     EVLALATDFVLGSLFARGYARPVKDALAAPPPLGLRMPLAAGFGASLRQ"
     misc_feature    complement(20575..20577)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tcaacgacct cccgtgcttc gacctcgtcg gctggcccgt ggcggtcgcg aacgcacacg
       61 acgtggtgcg cggcgcggcc cgcgctgtca ccgcgacgcc cggaggcagc ggcgcgatcc
      121 gagagatcgc ggcctggctc ctgggcccgt ccctgtaacc cacccagacc ccacctccac
      181 acaccccctt atcaacgcga aggaacctcc ccatgagcac caactcccgc ctccgcaacc
      241 tcggcaaccg cgaggccggc cccggccgcc ccgtctacgt caccggtgag atcggcatca
      301 accacaacgg cgacctggag aacgcgttcg cgctgatcga cgccgccgcc gacgccggct
      361 gtgacgcggt gaagttccag aagcggaccc ccgaggtctg caccccgcgt gaccagtggg
      421 agatcgagcg cgacaccccc tggggccgga tgacctacat cgactaccgc caccgcgtgg
      481 agttcgacga ggacggctac cgcgccatcg acgagtactg caagaagcgc ggcatcgcct
      541 ggttcgcctc cccgtgggac gtcgagtccg tcgccttcct ggagaagttc gacgtgccct
      601 gctacaaggt cgcctccgcc tcgctcaccg acgacgagct gctgcgcgcc atgcgcgcca
      661 ccggccgcac cgtcatcctc tcgacgggca tgtccacccc caagcagatc cggcacgccg
      721 tcgaggtcct gggcagcgag aacatcctgc tctgccacgc cacgagcacc tacccggcca
      781 aggccgagga gctcaacctc cgcatgatca acaccctcca ggacgagtac ccgaacgtcc
      841 cgatcggcta cagcggccac gagaccggtc tccagaccac cctcgccgcg gtcgccctcg
      901 gcgccacctt cgtcgagcgc cacatcaccc tcgaccgcgc catgtggggc tccgaccagg
      961 ccgcctccgt cgagcccggc ggcctgaccc gcctggtccg cgacatccgc accatcgagg
     1021 agtccctcgg tgacggcgtc aagaaggtct acgagagcga gctcggcccg atgaagaagc
     1081 tgcgccgcgt caccggcgtg gtcgccgagg ccgaggccgc cgagccggcc gccgtctgac
     1141 cgcccggccg acgaaccgac gggagccaag gtgaccacac ccgaagggac ccgcgccgtg
     1201 cccggcacgc ccggcgccga ggttccgccc ccggagacga cggatcctcc cgcccgtcgt
     1261 ctccgggggg tgccgcggca gcgtcaccgg accgcacgct ccggtgagcc gcgtacgggc
     1321 gcccgggaca ccggcaccct cgcgttcgtc gagagcccgg tgcagctgct gaacgtcctg
     1381 gagtgggcgc acacggcaca ggccaccggg ctcaccgtcg tcgtgctctc cccgcacgac
     1441 cccatgaccc gcggccagct gcggcgcatg gccgaactcg cccgcgacga aggccatacg
     1501 gtgcgctggg aggaggcccg cggcggcccg accgcgccga tgcgcaccat cggcggcctc
     1561 accccgctgc tgcgccgcgc ccgccgcgtc gtcatcggcg acccgttctc ccgctacgtc
     1621 cagctgctgc tctccctcgc cagggcgcgc gatctggtcg tggtcgacga cggcaccgcc
     1681 accatggagt tcatctccca actcgcccgc ggggaaaagc tggtgcgctg gcaccgcagc
     1741 ggcagcggcc gcggcgcgcg ggacctgatc ttcgccccgt tctccgccac cgcccggcgc
     1801 cggctcaccc cggctcccga gggcgggcgg cgcaccgtcg gcctgttcag ctcgatgccc
     1861 gtcgaggcgc ccccgggcgt cgaggtcacc accaacgagt tcgcctggac ccggggccgc
     1921 ttcggcccgc cccggctcac ccgcgccgcc gacatcgtcg gcacctcgct ggtggagacc
     1981 ggggtcgtgg acaccgagcg ctatctggcg gcggtcggca gcctggcccg tacgcacggc
     2041 gccacccgct acttcgcgca ccgcaaggag agcaccgaga agctgcgccg gctcgtggtc
     2101 gagaccgggc tggagatcgt ccggcccgat ctgccgctcg aactgatcgc ccggcgcggg
     2161 cccatcggac ggctgatcgt cagcttcccc tccaccgtgg tgcacaccct gccgctggcg
     2221 ctgcggggga cggaggtcaa ggtcgcggtc tgcgacatcg atccggagtg gctgacggcc
     2281 aacgcctcac cgcgggccca ggggttcctc gacggggtca ccggcaccgc ccgcgacgtg
     2341 cagcgactgc ccttcaccca gccgatggcc gccggatgaa ggagcgcggg aagccttact
     2401 gcatacccgt cgcataaacc atccatgcgc cgagcggcct gattttcttc ccctaacggg
     2461 ctgaactttt gttgatcgaa ggacagttgc ccccttaggg cccgtaacct tccacgggtg
     2521 aaccacgtga agtcccgaga ggtcagcgcc gcccgtaccc ccgccggtga tcagctcccc
     2581 ggcgcccttc ccgaggcact gcgtgccgaa ctcagcgcct tccggcgcga cttgcaccgg
     2641 cacccggaac tcggcaacca ggagttccgg accaccgcgg cgatcaagga acggctggag
     2701 cgggccggtc tgcggccccg ggtactggcc accggcaccg gcctgatctg cgacatcggc
     2761 acccgggacg ccatggccga cgggcaggcg gccgcgaccg cccccgaccg ccccctgctg
     2821 gcgctgcggg cggacatcga cgcgctgccc atcccggaca ccaagaacgt cgactacgcc
     2881 tcgacggtcg caggccgcgc ccatgcctgc ggccatgacg tgcacaccgt cgtcgtcctc
     2941 ggcgccggtc tggtcctggc cgagctggcc cgcaccggcg ccctgccgcg ccccgtgcgc
     3001 ctgctcttcc agcccgccga ggaggtgctg cccggcggcg cccccgacgc gatcgagtcc
     3061 ggcgccctgg agggcgtcgg ccggatcctc gccgtccact gcgacccgcg cgtcgacgcc
     3121 ggccggatcg ggctccgtac gggagcgatc acctcggcct gcgaccggct ggaggtcgag
     3181 ctggacggac ccggcggcca caccgcccgc ccgcacctga ccaccgacat ggtcaccgcc
     3241 gcctcccggg tcgccgtgga cgtaccggcg ctgctggccc gccgggtcga cgcccgcgcc
     3301 ggtctggccg tcacctgggg gcggctggcg tccgggcacg cctgcaacgt catcccggag
     3361 cacgccgaac tctccggcac cgtccgctgt cttgatctcg acgcctggcg gcaggccccg
     3421 gacctggtcc atgcggcgat cgacgaggtc gccgcgctgc acggtgcgaa gtcccagatc
     3481 acctacgtcc gcggggtgcc gccggtggtc aacgagccgg tcaccgtcca gctgctgcac
     3541 tccgcgatgg ccgcccgccg aggcgagggc gccatcgagg acaccgagca gtccctcggc
     3601 ggtgaggact tctcctggta cctcgaacac gtccccggtg ccatggcccg cctcggcgtc
     3661 cacccgcccg ccgaccccac gtaccgggac ctgcaccgcg gcgatttcga tgtggacgag
     3721 caggcgatca aggttggcgt cgaactcttc accggcgcgg ccctcctcga cggggacctc
     3781 gcggactgag cgcgcgcacc cgccgtaccg gccgggcccc tatagcggga cactgcccga
     3841 aatgactcca taacggcccg ttccggcagc ttgccgggac gggccgcgcg gcatgcccgc
     3901 ctgtgttgcg tttcgggtgc cctacgcctc gaatcgataa cgtccacgca gtggagggtt
     3961 ttgcgccagg tctacgcgcg ttaatctccc gacaagccag cgccaatggg ggcgcttaga
     4021 gcgaagggaa ggccccgtgc gtcgggtcat caggattgcc gccgcggcca ccgccaccgc
     4081 gggcctcgcg ctcaccgcca ccgcgtgcgg tcagagcttt gccgaggcca accgcgccaa
     4141 acacgcgggg gtcggggtgg ccttcgacat cggcggccgg gacgaccact cgttcaatga
     4201 agcggccgcc cgcggtgcgg acaacgcgac caagaagctg ggcgtcaacg ccaagatgct
     4261 caccgccaag aacggcgaga ccgaggcgga ccgcgagcag cggctcacct ccttcgccga
     4321 ggccggctac aacccggtca tcggcgtcgg cttcgcctac agccaggccg tgcagaacgt
     4381 ggccaaggac ttccccgcca ccaccttcgg tgtcgtggac gccgtgcccg agggcaagaa
     4441 cgtcgatgcg atggtcttcg ccgagcacga gggctcgtat ctggccgggg tcgcggccgc
     4501 gctgaagagc aagaaccaca aggtgggctt catcggcggc gtgaacaacg cgctgatcca
     4561 gaagttccag gccggcttcg agcagggggt ccgcgacacc gacccgaaga ccaaggtcac
     4621 ctcgcagtac ctgtacccca acaacgacaa ggggttcaac gacccggcgg ccgccaaggc
     4681 caaggccggc ggcatgctcg acagcgggat cgacgtgatc tacacggcgg ccgggcagtc
     4741 gggcgccggg accatcgagg cgatcagcaa ggtcaagggc gcctgggcga tcggcgtgga
     4801 ctcggaccag taccagcagc cgggtctggc ccgctacaag aaccggatcc tcacctcggt
     4861 cgtgaagaac gtcgatgtgg ccgtgttcga cctgatcaag agcgccgagg acggtaagcc
     4921 gctgaccggc atccactcct acgacctcaa gcacagcggg gtgtcgctcg ccacctcggg
     4981 cgggttcatc aaggacatcc agccgcagat cgatgcggcc cggaagaaga tcatcgaggg
     5041 caaggtgaag gtcaaggaga cgccgtagcc cgggaccacc gccgccccgg gtcgccgcag
     5101 cgccggaccc cgggggcgag ccaccgtccc ccttgtgacc ttccggtccc tgactttccg
     5161 tcctttccgc tccttcatcc ctgaggggag tgcgccatca acgcagcatc cacgagcagc
     5221 ggccccgccg tcccggacgc ccccgctgta gaactccgcg gaatcaccaa aaggttcccc
     5281 ggcgtcgtgg ccaaccacga catccatctc accgtgcgcc gcggcaccgt ccacgccctg
     5341 tgcggcgaga acggtgccgg caagtccacc ctgatgaaga tcctctacgg catgcagaag
     5401 ccggacgagg gcaccatcgc gctgggcggc gagcaggtca ccctgcacac cccgggcgac
     5461 gccatcgcac gcggcatcgg catggtgcac cagcacttca tgctcgccga caacctcacc
     5521 gtcctggaga acaccgttct cggcgcggaa aagctgcacg gcatcggcgc cggcgcccgc
     5581 gcgaagataa aggaactctc cgacgcgtac gggctgaaca tccgccccga cgtgctggtc
     5641 gaggacctcg gtgtcgccga ccgccagcgg gtggagatcc tcaaggtcct ctaccgcggc
     5701 gcccgcacgc tgatcctcga cgagccgacc gccgtcctgg tcccgcagga ggtcgacgcg
     5761 ctcttcgaca acctgcgcga gctcaagtcc gagggcctga ccgtcatctt catctcgcac
     5821 aagctgggtg aggtgctctc ggtcgccgac gacatcaccg tcatacgccg cggcaccacc
     5881 gtggcctcgg tcgagccgtc cgggaccacc cccaagcagc tcgccgagct gatggtcggc
     5941 agcgaactgc cgtcgccgga gacccgcgag tcgaccgtca cggacgagga gatgctccgc
     6001 gtcagcgacg tgcacctgtc cgcgaccgac tccgacggcg tggtccgcac cgttctggac
     6061 ggcatctcct tcaccatcca caagggcgag gtgctgggcg tcgccggtgt cgagggcaac
     6121 ggccaggccg agctggtcga ggccgtcatg ggcacccgcc gccccgacca cggcacgatc
     6181 accctggacg gcacggacct gtccggcgcc tccacccgcg cccggcgcga gggcggcatc
     6241 ggctacatcc ccgaggaccg ccaccgccac ggcctgctgc tggaagcccc gctgtgggag
     6301 aaccgcatcc tgggccatgt caccgagcgc cccaacagca agggcaagct cctcgacatc
     6361 cccggcgccc gtaaggacac cgagcgcatc gtcgagcagt acgacgtgcg cacccccggc
     6421 atcgaggtca ccgcgtcctc gctctccggc ggcaaccagc agaagctgat cgtcggccgc
     6481 gagatgagcc accaccccaa gctgctgatc gccgcccacc ccacccgcgg ggtcgacgtc
     6541 ggcgcgcagg cgcagatctg ggaacagatc cgcgaggcgc gccgcgaggg cctggcggta
     6601 ctgctgatct ctgccgacct ggacgagctg atcgggctgt ccgacaccct gcgggtgatg
     6661 taccggggcc ggctggtcgc ggacgcggac cccgccgtca tcaccccgga ggagttgggc
     6721 tccgccatga ccggtgccgc cagaggccac ctcagcgcgt cggaggacgg tgcgccggac
     6781 gacggcgcac cggcagacgg tgcgtcgcag gacgccggtg agcaggaggg cgacgagcag
     6841 tgagcacctc caccaagaac cccgccgtgg acgccatcgc caagagcgcc acccgcgaca
     6901 aggtgatcct cgcgatcgcc gcgcccgtcc tggccatcgt cgccgcgata gtgatctcgt
     6961 ccctggtgtt cctcgcctcc ggtgagaacc ccttccgggc ctacgggatc atggccgact
     7021 acggccacta cagcgacagc caggtctgga tcatcaacaa ggcggtgccg tactaccttt
     7081 cggcgctggc ggtcgccatc ggcttccgca tgaacctctt caacatcggc gtcgacggcc
     7141 agtaccgact ggcggccttc gcggccgccg ccgtcggcgg ggccatcgcc ctccccggcg
     7201 cgctccagat catcctgctc atcgtcatcg cgatgctggt gggtgccctc tggtcgggca
     7261 tcgcgggtct gctgaagacc acccgcggcg tcagcgaggt gatcaccacg atcatgctga
     7321 acgccatcgc cgcgtcgatt atcggctact tcctccagga cggccgcctc gccatcaagg
     7381 acggcaacct cctgcacacg aagttcctgc cggaatcgag ccacttcttc accttcccga
     7441 cccaccccaa gccggtcctc ggcttcgtgg tgatcgcgat cctggccggt gcgctgtact
     7501 ggttcgggat caaccgcacc cgcttcggct tcgacctgcg cgccgtgggc gcctccgagc
     7561 cggccgccga ggccagcggg gtcagcgtca agcggatggt cctgtgcagc atgctgctgt
     7621 cgggcgccgc agccggtctg gtcggtatgc ccaccctgct cggcgagtcc ttccagtacg
     7681 gcacggactt cccggccggt atcggcttca ccggtatcgc catcgcgctg ctcggccgca
     7741 accaccccgt cggcatggcc ttcggtgccc tgctgtgggc gttcctcgac cgcaccggct
     7801 cccggctgga gttcgagggc tacgcccagg agatcgtcgg cgtcatgcag ggcgtcatcg
     7861 tcctctgcgt ggtcatcgcc tacgagatcg tgcgccgcta cgggctgagc cttcagcagc
     7921 gcaaggtcgg cgaggagctg gccgccctgt cccgtacgaa caacaccgac aagtctgaca
     7981 agagcgacaa cccggaggtg tcggcgtgag tacggacctc aagaccgcga cgaagctcgc
     8041 ggtccccggg aagggtggcc ggcgcaagct gacctacccg tggatcctgc tgatcatcgc
     8101 cgtcgggctg gtcgctgtct ccgtcctccg ggccttcacc ggcgccggtg acctcacctc
     8161 caccggccag ttcggcgccg cactgagcgc cgccgtgccg atcggcctgg cgggtctggg
     8221 cggactgtgg tccgagcggg ccggcgtggt caacatcggc ctcgaaggca tgatgatgct
     8281 cggctcgttc gcggccggct gggtcggctg gcagcacggt ccctgggcgg cggccgcggc
     8341 cggcatcctc ggcggcgcgc tcggcggcct catccacgcc atcgccaccg tcactttcgg
     8401 cgtcgaccac atcgtctccg gtgtcgcggt caacatcctg gcgctcggtg ccacccagta
     8461 cctggccacg ctgtggttcg gccaggaggg cagcgcggcc atgctggccg gcggcaacga
     8521 caagcagtcg ccgccgatgc ccgacatgcc gacgttcacc gtgcccggtc tgtcggacgc
     8581 gctgaacacc ctggagggcc accactggtt cctggtctcc gacgtcgccg gcatcctcgg
     8641 cgccgcggtc accaacgtct cctggctgac cctgctcacc atcggcctgt tcatcggcac
     8701 cttcttcgtg ctgtggcgct cctcgttcgg gctccggctg cgctcctgcg gcgaggcccc
     8761 gatctcggcc gagaccctgg gtgtcaacgt ctactcgtac aagtacgcgg cggtgctggt
     8821 ctccggcgcc ctggccggcc tcggcggtgc cttcctctcc atcggggtgc acttcttcca
     8881 ggacggccag accggcggcc gtggctacat cggtctcgcc acgatgatct tcggcaactg
     8941 gcggccgggc ggcgtcgcga tgggcgcggg cctgttcggc ttcatggacg ccatgcagct
     9001 gcgcagcggc ggcccgaccg tccacgccct gctgctgggc ctggccgcgc tcctcgcggt
     9061 gctcgccctg ctccggctgc gtgccgccaa gcgcacccag ggcgtggtcg ccggcatagc
     9121 cgccgccgtc ctggtcatct ggtacttcct ggccgacacc gttccgctcg aactggtcga
     9181 ggcgagcccg tacatcgcca ccctgctggt actcgccctc ttctcccagc ggcttcggcc
     9241 gccgaaggcg aacggcaagc cctaccgccg aggacaaggc acatgacacc accggtgccg
     9301 gtcgactgga ccgcactgcg cgcgcaggcc cgggacgcca tgtcccgggc ctacgccccg
     9361 tattccggct accccgtagg cgccgccgcc ctagtggacg acggccgcac catcaccggc
     9421 tgcaacgtcg aaaacgcctc atacggcctc gccctgtgcg ccgaatgcgg cctgatctca
     9481 gagctgttcg cgggtcgccc cgacaacgac gggcccaccc cgcggctgac cgccttcacc
     9541 tgcgtcgatg gcactggcgc cctcctcgtc ccctgcggac gctgccgcca actcctgtgg
     9601 gaacacggcg ggcccgacct cctggtggac acgatggcgg gcatccgccc cctgtcggag
     9661 ctgcttccgg acgcgttcgg ggcggggcat ttgagggggt gacggggagc ggtgggtggc
     9721 agtgactcca tacccgccac ccaccgcgcc cggcaccacc tgctcaccgg gcaagacgca
     9781 ggtcgagcaa gacgcaggtc gatccaggga atgctgtccc ccggcagcag atagcgctcg
     9841 gtctcgacaa acccgtgctt ccgcgcgaac cgcagcccgt cctcgttgga ggacaacacc
     9901 acggtctcga tcacttcggc acccaactcc cgcgcccgcc cgagcccgcg cgcatagagc
     9961 tcccgtcgcg gccattcagg cggggcggat ggtcagcccg tcacggtcga gtcatctgca
    10021 cttcggacac ttcgagcaat ccgtcgagtt cgaccttccc cctggtctgg cccgggttca
    10081 ccaccaggcc gtcccgtcgc acgatgtcca ggagccgttc ggccaggggc aggaccatat
    10141 gccggcccca gcatcgttcg cttacgtggc cgaaggggag atatccgggg tggttgtctc
    10201 cgtccagctc ttcccagcgg ctgggatgaa acgcgtcggg ttcgtcccag agctcggggt
    10261 cgcggtggct cagcagggga agcaacagga catcgtcttt cgggccgatc cgtgcgtcca
    10321 cgtccgagaa ctccggagaa gccatgcgca agatgttcca cgagggggga agtagtcgga
    10381 gtgcctcaag gaggatgttc cgattcgata cgtcgtcgct gaacggagcc ccgagccaca
    10441 gggcattggt gaccagcgcg gatacggtga agcacaccgg tgctgccacc cgccgataca
    10501 ggtacatggc atagcgccgg tcaccgtagg tcgtggaatc gagcacgaga gcggcaagtt
    10561 tcgacagcgg cacgtcctgt ccgggcctgc ccagcaaagc ggctccggag gcgacggccg
    10621 accaggtcag tttcggtgtc aactccagcc tgcggtcgac cagaacccgg aatcgcagac
    10681 gttcgtttcc gaaaacgaga ttccgcaggt aaacatgcgc cacatgcggc caccggccgg
    10741 tcaggtcgac cgcctcatcc aggggacgct gcagcgcgtt ccgcacgtcc gagcccacgg
    10801 cttgcataaa ggtggacgca tccgtacggc taacgagccg cccctggacg ggtttgaagg
    10861 tgggcctctc ctccgcgttg gccggcctgc tgcggagtaa gcggtccatc agctcggcgc
    10921 cggatacccc gatcgtgtcc ggctccagac gaaaaagcga cgcaccacga taacgactta
    10981 acagctcgtc gattctcggc gcgaactcga taacccgacc gctctcgccg acgcggtgca
    11041 taggcatggc tgaactccgt gggtaggcag ctcgcgccgg ccagaactcc tgaccgacgc
    11101 gagcccggca gggaagctgt ctaattaaat ccagccgtac caggcgtacg ccttgaggct
    11161 cttttccgga cggaacttct tgacgatgcg aacgagtttc atgagcacct ccatttgtgc
    11221 ggtgaacgag acacttattc gacggcagaa gatgtcgata ccggtcagaa ttcccggcat
    11281 tcatttcaac tgctgcggaa agtgaagacc taaccggtga atgtgtcaag tgatccacat
    11341 cactacctga attgcctcat tcacgtttcg aattcatccg tattcacatc tcggcaaatc
    11401 atcgctaatc cactcattga aacccaatgt gggcatcaaa agggagcgga tggcgtcgga
    11461 tggggtggtt tagccccata tgtatgacat gaacatgttc cataggggcg ggtcgaaggt
    11521 ctccggtccc tgctccggcg cggcggctct ccagcacgga aatcgggcga agcggcggtg
    11581 aagctggcgc agtcggtcgt ctcggcgcgg ctcgcagccg gggcgcagat cgtcggcccc
    11641 gtcggctcgg tgttctggca ccagggcgag ttcggctcgg gcgaggaatg gcaactcgtc
    11701 ctcaagatcc gagccgaccg ttacgacgag gtcgaggcgc atctgctcaa gcaccacccc
    11761 tggcagaacc ccgaagtctc cgcagtgccg atcgttgccg gggcgaacgg ctatctgcgc
    11821 tggctggaga cgaccacggc accggactga cgtcaggctc gtgccagttc cagtacctcg
    11881 gctatttcgg gtggttcgcc ggtgagagct gagtcggtgc agggtcgatt tcagcgtgtg
    11941 gcgggcatat tgccatcgcg ccaatcgttc aggcgctttc ggatgctggg caccatcgga
    12001 agcgcatcaa tctctccggg ctcaaaccac cggacgtccg tggattctcc ggacaccgcc
    12061 agctgcccgc ccaacggtct cgccaggaag cagatggaga attcctgccg cacttcgcca
    12121 tcgtcgtaag cgaagacgtg atgggggttg gtgtaggtgc ccacgatgcc tacgacttcg
    12181 acatggaacc cggtctcttc gcgggtctcc cgaactgcgc agtccggcag tgactcgcca
    12241 atattcatga cgccaccggg aagtgcccac atgccgttgt cgcgccgacg ctgaagcagg
    12301 acgcgcccgg agtcgtcgat cacgaccgca gatgccgccg gaaccaagct gttcgcggca
    12361 ggggcatgag ggtcgttctc gtagtcgcgc ctactcatcg ccgccgcctt cccacaccgg
    12421 agagcccctt tcacagttct tctacgcact cgggattgcg cacccgcgcc tttagctctg
    12481 ccccgatcaa gacacgatcc acggctcaga cggtacgggc tccggttctc atcatggagg
    12541 cgaacttcgc ccgttggcgg catcagtacc gggccccggg tatctgccca cgaaccccgt
    12601 acgggccgta cgctggctgg gacggctacg ccacccagag ggggcacgca tggatctgtc
    12661 ggacgagctc ggcaccggcg agcggatcag ggttctgcgg gagtcgcgcg gcatgacccg
    12721 tggcgccctc gcccacctct gcgggcgtgg cacggactgg ctgaagaaga tcgagaccgg
    12781 cgaacgtgaa ctccgctccc ataccctcct gttgcgcctc ggtgccgcgc ttcaggtgtc
    12841 cgacctctcc gttctcaccg gggacagtga cggcccggcc cagctggtgc cgctcggcag
    12901 gctgaatcat ccggccatgc ctgagatctg gaccgcggtg atgaaccggt ccctgaccac
    12961 cgcggccacg ggccccctcg aaccggctgt gctgcaaggg cgcgtcgacc agacatggcg
    13021 cctgtggcac accaccgatc gcaaccgcac cgaggtgggg gctttgctcc ccggcctcat
    13081 ccgcgacggg gaagccgccg tgcgggcgct cgacggtgac cagcgccgtg ctgccctggt
    13141 ggcgctgtcc gacgtgtacc ggctcacggg ccaggccacc gcctacgtcg ctcccgccga
    13201 gctggcgtgg gtcgtcgccg accgtgccct gtccgctgcg caggacgccg atcagcctgc
    13261 cgccatagct gccgccgcat ggaacatggg caacatcctg cgcgaaacgt cgtatccgga
    13321 ggaggcgttg cgcatcgtcg ctgaggccgc cgacctcatc cggccgcacc tcgatgacgc
    13381 tcccgacgac tggcgcggca tctacggtgc gcttcagctg cacgccgcgg tcacggtggc
    13441 gcgagagggc cgcgagggcg acgcgtggcg gtactgggac aagggcgacc aggtggcgaa
    13501 gtccttgccc gcctcgtacg tccacccctc caccgtgttc ggccgggcca acgtcgattt
    13561 ccacgccgtc agcgtcgcga ccgatctgcg caaggcacaa aaggcgcttg ggctcgctga
    13621 cgaccttgat ccggatgtga tgccctcccg cgagcggcgt gcccgactgt gggtggaagt
    13681 cgcccggggg caccgacagc gcggtgaccg gaccgccgcc ctgcatgtga tgcagatggc
    13741 ccaccggatc ggcgccgaga ccgtcaccta caccccgtcc gcccgtgtcg tagccgcaga
    13801 cctgtggcgc tccgcgccgc gcgcgatgcg taaggacgcc ggccggctgg ccgaggccgt
    13861 cggggtcgcg accgcctgac cagagggaca tacagggaca gggggacaat ctgtccccct
    13921 tttcccttgc acgggcccct acggtggcgc acctgcctcc gcgccgaccg aacggggtga
    13981 cacatgaatc cgggcgcccg attgcacgca tcgacccgcc ggggcgaacc gccctccgcc
    14041 gacggcgtca cgggggagat ccgcgtaccg ctggccctgt acgccgtcga tgagcaccgc
    14101 ggcagtgttg acctcgtgct gtcgcgcgcg gacacggcat cgctgcttgc ctcgctcgtg
    14161 gaggccctcg gcgcccccac gcacgcatcg cggcctcagc gcccggagga cgcgcggtga
    14221 tcaaccaatc cggcttggga aaggcgcgaa cgccccaagc cctgtccgac aacaaagacc
    14281 cccgcgacgt tgctgcgtcc gggggcgtgg ccatcaaccc ctgggaggtt gacgacatgg
    14341 cgaagactat cgccaggatc ttcgaatcgc tgctgcggct gttactgcct gcccgagggc
    14401 ggcaccggtc cttcggctgt atgcccaccg tgacgtgtga ggacgcgccg accctcgtgt
    14461 ttgcccgtgt gcccggcgga agggaggggc tgttgcgggg cgaggacgcg gcgcttatcc
    14521 ggccgtacgc cctcaccccg gaggagcggc agaaacgacg gttggagtac gggcggcgac
    14581 gggttcagtt gtttgcggca tatggcactg acgctgcccc gcgctggctg aacggcctgg
    14641 aggcggcagg ccgatgagtc caaccgacac ccctcgcctc ctgccctggt cgagcaccga
    14701 cgggaagccg tgctttctcg taggtagcgg gaccggctac gtgtcccggc tcgccgacga
    14761 gatggaggag gcgcagctcg actccgccgc tgaactcggc gaagaggcgc accgcatcct
    14821 ggcgggccgg gcatggactc ccggcgaaat tcatctgctg gcgctggaat tggccgcttc
    14881 cctcgccgac gtacgccggg tcgcggagag caggggcgcg cgcctgcccg tgccggacga
    14941 tgacggttcc gacggggacg atgcaccgga cgacgagggc ggcgacaggc cacggcttcc
    15001 ggcggaggcg ttcggatgag ccgggcacgg tgtgcggacg agtggtcgcg gctgcgctgc
    15061 tgaacggagg aggcgtcggc gaggcggcgt gagccggcgg tagaggtacc tcccgctctc
    15121 tccgcacccc tgcggccgct ccgggcgatg gtgctcgttc acacacctgg cccggagcgg
    15181 ctttcgtcgg cgcccccagc gaccgcccac cccgccccgc ccccgggcac cgccctgccg
    15241 ctccctatgc acccacccca cccgcagccc ctggccaccc cgccgtctat gcgtgtagaa
    15301 cggacctacc cgttcgaaag gaactgtcca tggacgccat ctccgtcatc cgcaccaagc
    15361 gcgaccgcgg tgagctgacc cccgatcaga tcgactgggt catcgacgcc tacacccgcg
    15421 gtgaggtcgc tcacgagcag atgtcgtcgc tggcgatggc catcttcctc aacgggatga
    15481 accgtacgga gatcgcccgc tggaccgccg caatgatcaa ctccggcgag cgcatggact
    15541 tctcctccct gccccgcccc accgccgaca agcactccac cggcggcgtc ggcgacaaga
    15601 tcaccctccc gctcgccccg ctggtcgccg cctgcggtgc cgccgtcccg cagctctccg
    15661 gccggggcct cggccacacc ggcggcaccc tcgacaagct cgaagccatc cccggctggc
    15721 gcgcgagcct ctccaacgcc gagatgctgg acgtgctgcg cgacgtcggc tccgtcatct
    15781 gtgccgcggg tgacgggctc gcgcccgccg acaagaagct ctacgcgctg cgcgatgtca
    15841 ccggcaccgt cgagtccatc ccgctcatcg cctcctcgat catgtccaag aagatcgccg
    15901 agggcaccgg ctccctcgtc ctggacgtca aggtcggctc cggcgccttt atgaaggacc
    15961 tcgacaacgc ccgcgaactg gcctccacca tggtcgagtt gggtgccgac cacggggtgc
    16021 ggacggtcgc cctgctcacc gacatggcca ccccgctcgg tctcaccgcc ggcaacgccc
    16081 tggaagtccg cgaatccgtc gaggtgctgg ccggcggcgg cccccaggac gtcgtcgagc
    16141 tgaccctggc gctcgcccgc gaaatgctgg acgcggccgg gctcaaggac gccgacccgg
    16201 ccaaggcgct ggccgacggc tccgccatgg accactggcg ccgcatgatc gcggcccagg
    16261 gtggcgaccc cgacgcggcc ctccccgtgg cccgcgaaca gcatgtcgtc accgccgcct
    16321 cctccggcac cctcaccacc ctcgacgcct acgccgtcgg cctcgccgcc tggcgcctgg
    16381 gcgccggccg cgcccgcagg gaggacccgg tccaggccgg cgcgggcgtc gaactccacg
    16441 ccaagcccgg cgacacggtc gctgcgggcc agcccctgct gaccctgcac accgacaccc
    16501 cggaaaagtt cgcctacgcc ctggaggccc tcgacggcgg cgtgctcatc ggccccgagg
    16561 acgcggcctt cgccaccact ccggtggtgc tggagcgtat tgcctgacct gcggttttcc
    16621 ggccggaggc ggttgttgac ggggctcgta cgagtgaacg ggatctgcgg acagccgcgg
    16681 gtcccgttcg gcgtggtgga gtcggctgta cgtgtcgaag ccgaggagcc cgcagtgatc
    16741 gcactcaccg ccgagcattt cccagaggag ggccgcgtct gggacgccct ggtccgcatc
    16801 tgggaggaca ccgaggcgcc tgaggcctgc atggtggaga tcgtggacgg catcgtcacc
    16861 gtcgccccgc cgcgcgatgt ccggcagaac gtgatcgtcg ccgagctcag ccgcgccctg
    16921 taccagcagg cgctccctga gaaccgaggc gcctaccaga aactcgccct ggccgttccc
    16981 gcccgcaagg gcctctacgt ccccaacctc gttgtggccc ccgattccgt ggttcggggc
    17041 ccagggcgct tcatccctgc cgcggctgcc gaactggtcg tcgagatcac ctcaatgacc
    17101 tctgcggtcc acgaccggct ccataaaccc gccggatacg cctccgcagg cgtaccgctc
    17161 tacctgctca tcgacctctg gtcgcccgac ggcccgaccg ccactctcca tggcgagccg
    17221 gatcacacgc gctaccgcaa ccagcgctcc gcacgcctcg gtgagcggct ccacctcccc
    17281 gagccgttcg acatgaccat cgacacgtcg ctctttcgcg tcagttgacg acgaagagcc
    17341 cgccccacca ggacaggtgg agggacgggc ccttcggact gcggggcgtg ggcgttacgc
    17401 ggccttctcc aggtggagga ggcggcgttc ggcgacggcc ttgcgggtgg cgtagagggt
    17461 gatcgaggcg gcgccgagca tcgcggcgag gccgaggagg acggtgccct cccagccgac
    17521 ggcgtggaag gcggcggcgc cgagcgcgcc gcccaggctg ctgccgacgt agtacgcgca
    17581 ctggtacagc gccgaggcct gggcgcgcgc cgtcttggcg gtgcggctga ccgaggacga
    17641 ggccaccgca tggcccgcga agaagccggc ggtgatcagg atcaggcccg ccagcaccgc
    17701 gcccaccgag tcggagagcg tcagcagcag acccgtcgag gtcgtaccga cggccaggta
    17761 cagggcgccc cggcggccca cccgggcgac cagcttgccg gccgcggccg aggagaccgt
    17821 accgaccaga tagaccacga agatcgaacc gacgatgccc tgcgggaggt tgaacggttc
    17881 ggagaccagg cggtagccga tgaccgtgta gaccgcgccg aagaccgtca tgaacagccc
    17941 gccgatggcg tagagacggc gcagcagcgg gtcggcgagg tggctgccga gcgtacgggc
    18001 cagcgcccgc gggcccaccg aacgggacac gaagtgccgg gccttgggca ccagcagccg
    18061 gaaggccacc gcgcacacca cggccagcac acccaccgcg gcgagcgccg cccgccagcc
    18121 ccacgcctgg gcgacccagc cggtcacgat ccggccggac atcccgccga tgctgttgcc
    18181 cgccacgaac agtccgatgg ccgccaccag cgccttcgcg cgtacctcct ccgccaggaa
    18241 cgccatcgcc gaggccggca gtccggccag ggcgacgccc tgaaggccgc gcagcgcgat
    18301 cagcgcaccg agcgacgggg cgaacggcac cagcatcgcg agcagcgcgg ccaccgcgag
    18361 ggaccacatc atcagcgtgc gccggccgaa gcgctcggag accgcgctca gcgggatcac
    18421 accgagcgcc aggccgaagg tcgccgcgga cacggtccag ctcgcctggt ccgggctcac
    18481 cccgaggtcg gcggagatcg cgggcagcag cgcctgcgtg gagtagagga gggcgaaggt
    18541 cgccactccg gcggcgaaga gggcgaagct catccggcga tagccggggc cgcccggccg
    18601 cagcttgccc gcttcggggt cgggcgcggc ggcgggagag gagtcagggg aggactgggg
    18661 agaggcggcc gcacggtcga tgacggacgc cccggtatca gcgggaggca tgtttcgaaa
    18721 gtaggcctct gtgtttcatg cgtccaatgc atggaaacgg cataatcgat gctgtggcac
    18781 atgatcccag gtcgcaaggg cctctgttgc aaggtcgcaa cagaaaagac atcgctgatt
    18841 cgggtcgcgc cggggcggac gcgggcgagg tggccgagct gggcgccgac tcgtgggcgg
    18901 tgacgctcgc cccgcggctc gcccaattca ccgccgtcgc ccggcacgag cacgtcaccc
    18961 gcgccgcgca ggagctcggc atgccgcagc cgacgctcag ccgggccatc gtccggctgg
    19021 aggaggacct cggcgtcgcc ctcttcgccc ggcacggccg caccctctcc ctcactccgg
    19081 ccggccgcgc ctttctcgcc gccaccgagc gggcgttgac ggacctggag cgggcgacgg
    19141 agtccgtacg ggccgatgtc gatccggcgg ccgggaaggt ggcgttcggc tttctgcaca
    19201 ccctcgggcc ggagaccgtg cccggcctga tccgcagctt ccgcgccgac catccgcgcg
    19261 tccgcttcca gctcgtccag acgtacggcg aggccatgat cgagcggctg cgcgccggcg
    19321 acctcgacct gtgtctgacc tcgccggtgc ccgactaccc ggacctggtc gcccgccggc
    19381 tcgacgagca gaagctgcgc ctggtcgtgc cggacgacca tccgctggcc gcccgtaagc
    19441 ggatccggct cgcggaggcc gccggcgagc tgttcgtgac cctcgaaccg ggctacgggc
    19501 tgcgccggat caccgacgcg ctctgcgccg aggcgggctt cacgccgcgg gtcgcgttcg
    19561 agggggagga ggccgagacg ctgcgcggcc tggtcgcggc cgggctgggc gtggccctgc
    19621 tcccgccgcc gcccgtcccc cgccccggcg tcgccgagct gaccgtgacg gcaccgcgcg
    19681 cggtccgcga gatcggcgtc gcctggctcg acggccaccc ggacacccca ccggtggccg
    19741 agttcaagaa gttcctgctg agccgacggg ggcggttgct gcccaggtga ggggcgtggc
    19801 cgccagttgc ctccgcagac ccggcggcgg cccgaccagc ccaccgccgg gtgccgggcg
    19861 acgggtgccg gatgccgggt gcaccggccg ggctcccggc cctcactgcc gcaacgacgc
    19921 cccgaacccc gccgccagcg gcatccgcag acccagtggc ggcggcgcgg ccagcgcgtc
    19981 cttcaccggg cgggcgtagc cccgggcgaa cagcgagccg agcacgaagt ccgttgccag
    20041 ggccaggact tcggcacggt gctgatgcag cgagtggccg tcggagtgca cctcgaagcg
    20101 gcagatgtcg cggttgacct tcttggcgcg ctcggcgtag cggtaggaga gatcggggtc
    20161 ggtgcgttcg tcgttggtgc cgtggacgag caggacctgg cggccgatga gctgtttcac
    20221 cggatcgggg tgctcgctgt cccggtgcgg gtcgggcagc caaggggcga tcgccagtac
    20281 ggagttgacg gccggatggc ccgcggcgtg cagggcggcg cgggcgccca tgcccgtacc
    20341 gacgaggcag accgggacat cgccgtagcg gcggaccacc tcctccagcg cccattgcgc
    20401 gtcccgcgcc ggatgggccg cggccccgtt ccagccgtga cagcgatagc gcacgacatg
    20461 ggccgtcagg ccctcagggc gtcccgcctt cgccagccgg accgccagcg ggcgcaccgc
    20521 cagcgccgcc accggcgacg ggcgccgtac cccggtcggt ccgccgccgg gcagtaaaag
    20581 cgcgacaccg ctcacctccc ggccggtgcc ccgcctgccg cccttccacc ggagcgcttc
    20641 gcgcgccccc tccttgccgg ccgttcccag cggttttccc agccgggcct cacgcaccgg
    20701 aagtgcttgc tgagccatga gcagaacgat ggcagaagga ggcctgcagg ccaccccgcg
    20761 gacgggtcac tgttatgtat cgttcgatga gatctacgcg cgtaggggct agagtgccga
    20821 aatgacgagc gagaccacca ccctgccgac cagtgaacag atccgccgcg cccccaaggt
    20881 gctgctccac gatcacctcg acggcggcct gcgcccggcc accatcgtcg agctggcccg
    20941 cgagaacggc tacgagggac tgcccgagac cgacccggag aagctcgggg tctggttccg
    21001 cgaggcgtcg gactccggct cgctggagcg ctacctggag accttcg
//
