LOCUS       NZ_CP050976            21062 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3403880
            Orig. end                         :: 3424942
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21062
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21062
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21062
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11062](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11062
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(322..1479)
                     /locus_tag="HEP86_RS15300"
                     /old_locus_tag="HEP86_15300"
     CDS             complement(322..1479)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969014.1"
                     /locus_tag="HEP86_RS15300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15300"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_168479217.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.8e-31, bitscore:
                     106.3, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.5e-24, bitscore:
                     83.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-43, bitscore:
                     147.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTVFNEDHEAFRETIRAFIEAEVVPVHDEWFAAGQVPREFYYK
                     LAELGVFGIRVPEEFGGAGIDSHKFEAVMYEETSRAGVTFGGSGVHVLLGLPYIQMLAT
                     DEQKKRFLPKFVSGEEMWALAMTEPGTGSDLAGMKSTAKLSEDGTHYVLNGAKTFITGG
                     VHADRVIVCARTAAPREDDRRFGISLFAVDAKSAGYSVGRKLDKLGLKISDTAELAFVD
                     VKVPVEDLLGEENKGFAYLGLNLASERWGIAFGAYAQAKAAVRFAKEYVQERTIFGKTV
                     SSFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRC
                     LQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEVMKSIIAKSMGL"
     gene            complement(1609..2250)
                     /locus_tag="HEP86_RS15305"
                     /old_locus_tag="HEP86_15305"
     CDS             complement(1609..2250)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093080.1"
                     /locus_tag="HEP86_RS15305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15305"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_168479218.1"
                     /transl_table=11
                     /translation="MSNAQPATPTSRREQILKEAARLFAERGFHGVGVDEIGAAVGISG
                     PGLYRHFAGKDAMLAELLVGISERLLAGGRMRVTEGGGSPEAVLDALIDGHIDFALDDR
                     PLITLHDRELDRLREADRKRVRQLQRQYVELWVEVVRRVHPGPSESRARAAVHAVFGLL
                     NSTPHLGRPGALPGRTEMAELLHRLALGAFGAVAGEPESGEPMAASVPGA"
     gene            2385..4016
                     /locus_tag="HEP86_RS15310"
                     /old_locus_tag="HEP86_15310"
     CDS             2385..4016
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062850.1"
                     /locus_tag="HEP86_RS15310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15310"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_168479219.1"
                     /transl_table=11
                     /translation="MEQAPVLGSTADPASDSWRANEAAHRELAAQLREKLAAARLGGGE
                     KARARHTARGKLLPRDRVDALLDPGSPFLELAPLAADGMYGGAAPAAGVIAGIGRVSGR
                     ETVIVANDATVKGGTYYPMTVKKHLRAQEIALENRLPCLYLVDSGGAFLPMQDEVFPDR
                     EHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLV
                     KAATGEVVTAEELGGGEVHAKTSGVTDHLAEDDAHALRLVRTIVGTLGERAPLPWTVRT
                     VEEPKADPAGLYGAVPADSRTPYDVREVIARLVDGSRFAEFKAEYGTTLVTGFAHIHGH
                     PVGIVANNGILFSESAQKGAHFIELCDQRGIPLLFLQNISGFMVGRSYEAGGIAKHGAK
                     MVTAVACTRVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLA
                     TVKRDQLEAHGEEWSAEDEAAFKAPVREQYETQGSAYYASARLWDDGVIDPLETRQVLG
                     LALTACANAPLPEKDSTAPGYGVFRM"
     gene            4034..6043
                     /locus_tag="HEP86_RS15315"
                     /old_locus_tag="HEP86_15315"
     CDS             4034..6043
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605451.1"
                     /locus_tag="HEP86_RS15315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15315"
                     /product="acetyl/propionyl/methylcrotonyl-CoA carboxylase
                     subunit alpha"
                     /protein_id="WP_168483747.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6e-09, bitscore:
                     34.5, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTNFDTVLIANRGEIAVRVIRTLRALGIRSVAVYSDADADARHV
                     READTAVRIGPAPAAESYLSVERLLEAAARTGAQAVHPGYGFLAENAAFARAVTDAGLV
                     FIGPSADAIELMGDKIRAKETVREAGVPVVPGSSGSGLDDGQLAAAAREIGMPVLLKPS
                     AGGGGKGMRLVRDETLLADEIASARREARSSFGDDTLLVERWIDRPRHIEIQVLADGHG
                     NVIHLGERECSLQRRHQKVIEEAPSVLLDEATRAAMGEAAVQAARSCGYRGAGTVEFIV
                     PGKDPASYYFMEMNTRLQVEHPVTELITGLDLVEWQLRVAAGEVLPYAQEDITLTGHAI
                     EARICAEDPARDFLPTGGTVLALHEPQGGGTRTDSGLLEGGEVGSRYDPMLSKVIAYGP
                     DRASALRRLRAALAETVTLGVTTNAGFLRRLLAHPDVVSGELDTGLVEREAAGLVDGTV
                     PEEVYAAAAAVRQAALEPAVADGGWRDPFAAPNGFRLGGEPAPVRHWLRIPGHDPVPHD
                     VRPGAPAGQLEPGRVRVTVDGVLHTFHHSGDWLGRDGDSWQVTSHDPVAAALRGAAGAH
                     GADTLAAPMPGTVTVVKVAVGDEVTAGQGLLVVEAMKMEHVISAPHAGTVTELDVTAGS
                     TVAMDQILAVVAPHESPDEAAASPAAPENGQESA"
     gene            6043..6984
                     /locus_tag="HEP86_RS15320"
                     /old_locus_tag="HEP86_15320"
     CDS             6043..6984
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093083.1"
                     /locus_tag="HEP86_RS15320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15320"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_168479220.1"
                     /sec_met_domain="HMGL-like (E-value: 4.2e-46, bitscore:
                     156.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPGLPMEVPAEGLPTRVRIHEVGARDGLQNERTVVPTEVKAEF
                     IHRLAAAGLPTVEATSFVHPKWVPQLADAEQLFPLLDDLDPQRLPVLVPNERGLDRALA
                     LGARRIAVFGSATESFAKANLNRTVDEALAMFAPVIARAKGARVEVRGYLSMCFGDPWE
                     GPVPVAQTVRVCRALLDLGCDELSLGDTIGVATPGHVQTLLAALNEAGVPTSRIGVHFH
                     DTYGQALANTFAALQHGITTIDASAGGLGGCPYAKSATGNLATEDLVWMLHGLGIETGV
                     DLDRLTATSVWMAEALGRPSPSRTLRALSHKE"
     gene            6990..8138
                     /locus_tag="HEP86_RS15325"
                     /old_locus_tag="HEP86_15325"
     CDS             6990..8138
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093084.1"
                     /locus_tag="HEP86_RS15325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15325"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_211117352.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.9e-37, bitscore:
                     126.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.8e-19, bitscore:
                     67.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.1e-48, bitscore:
                     164.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLDHRLPDELEELRRTVEAFAHDVVAPKIGEYYEQHAFPYEIVQ
                     EMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPVYHFG
                     TEEQKRAWLPKLCSGEMLGAFGLTEPDGGSDAGTTAVRDGGDWVINGSKCFITNSGTDI
                     TGLVTVTAVTGRKDDGSPLISSIIVPSGTPGFTVGAPYSKVGWNASDTRELSFSDVRVP
                     AANLLGEEGRGYAQFLRILDEGRIAIAALATGLAQGCVDESVRYAKERHAFGRAIGTNQ
                     AIQFKLADMEMRAHTSRLSWRHAASKLVHGEPFKKEAALAKLYSSEIAVDNAREATQIH
                     GGYGFMNEYPVARMWRDAKILEIGEGTSEVQRMLIARELGVV"
     gene            8539..9981
                     /locus_tag="HEP86_RS15330"
                     /old_locus_tag="HEP86_15330"
     CDS             8539..9981
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576907.1"
                     /locus_tag="HEP86_RS15330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15330"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_168479221.1"
                     /transl_table=11
                     /translation="MSVPDGVTGSTTEEPALAPPADSAPTSLGTQAARQLATTTKSEPQ
                     MQAITSRWLLKTLPWVDVKGGAYRVNRRLQLRVGRGRVQFEQNGADDIRVIPQTLTELP
                     ALRGYPDTEVLKELAGRFRVREVRAGQVLFEAGQPTTEAYLVVHGRFARYTAGKYGDEE
                     VIGVVTDGDQMGDEAIGRPDPRWLSSVRAETAGVLMVLPWDVVREFTDRVPSLAAHLTA
                     YAEQQQRPMNRKGEAEVPVRAGHVGEPTLSSGFVDYDLAPREYELSLTQTVLRVHSRVA
                     DLYNDPMDQTQQQLRLTVEEIRERQEWEMVNNREFGLLHNADYGQRISTYTGPPTPDDM
                     DELLSMRRKTRLFLAHPKAIAAFFRQCNKRGLVPGTANVDGHEVPAWRGVPIFPCGKIP
                     ISDSHTSSILALRTGEADQGVVGLHQTGIPEEYQPGLNVRFMGIDPSAVINYLVTAYYS
                     LAILVPDAVGVLENVQIGRSAD"
     gene            10001..11062
                     /locus_tag="HEP86_RS15335"
                     /old_locus_tag="HEP86_15335"
     CDS             10001..11062
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093087.1"
                     /locus_tag="HEP86_RS15335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15335"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_168479222.1"
                     /sec_met_domain="T1TS (E-value: 4e-50, bitscore: 170.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPPNTAATWSMPGPPNLARTLRTRRPGGAVPGLRYRPAAPADP
                     EKAAEIDRRLEAWARRLDLFPAQWTGDFTEFQFGRAVVLQHPGAADLERLTAAGKLLLA
                     ENIVDNCYCEEDEGKGGAHRGLGGRLIMAQSALDPLHATPELEEEWRHGVQADGPLRSY
                     HWALKDYAALATPSQTDRFVQDIARLHLGYLAEAAWAETRHAPRVWEYLVMRQFNNFRP
                     CLSIVDAVDGYELPEALYARPEVQRVTALACNATTIVNDLYSFTRELASDPHHLNLPQV
                     VAANDQRGLKDAYLKSVEIHNQVMAAFETESAPLSATSPLLERYVRSLADWVSGNHEWH
                     ATNTDRYQLPNYW"
     gene            11095..11970
                     /locus_tag="HEP86_RS15340"
                     /old_locus_tag="HEP86_15340"
     CDS             11095..11970
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574303.1"
                     /locus_tag="HEP86_RS15340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15340"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_168479223.1"
                     /transl_table=11
                     /translation="MTIAHADTARTPVPTQSTYQSRVADYWNAEENPVNLELGKIDDLY
                     HHHYGIGDADRSVLNEPDPGRRRDRVTGELHRLEHAQAELLASHLGDVSPTDRVFDAGC
                     GRGGGSVVANLRYGCHTDGATISAKQADFANAQARKRGVDDKVRYHHRNMLDTGFTTGA
                     YAASWNNESSMYVELDLLFAEHARLLRRGGRYVVITGCYNDAYGRASREVSLINAHYIC
                     DIHPRSAYFRAMARNRLVPVHVEDLTAAALPYWELRREADHLVTGIEDTFLTAYRNGSF
                     QYLMIAADRV"
     gene            complement(12020..13624)
                     /locus_tag="HEP86_RS15345"
                     /old_locus_tag="HEP86_15345"
     CDS             complement(12020..13624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093090.1"
                     /locus_tag="HEP86_RS15345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15345"
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="WP_168479224.1"
                     /transl_table=11
                     /translation="MRRRRLLFSLLLVAAAGLGTAAVPPQGAAGAAPRAATPLDRVIPA
                     PASVRGGGEAYTLGDRTRIRVPGGSGEAKRIAGYLAGLLRPATGLALPVTTKDGRDGIV
                     LRLGGSGTGGLGAEGYRLTSDGRAVTLSAARPAGLFHGVQTLRQLLPADLEQQRARRGP
                     WRIAGGTIADSPRYGYRGAMLDVSRHFFTVAQVKRYIDQLAMYKINKLHLHLSDDQGWR
                     IAIKSWPRLATYGGSTQVGGGRGGYYTKDDYREIVRYAAARYLTVVPEIDMPGHTNAAL
                     ASYAPLNCNGQAPPLYTGTQVGFSSLCVPKQETYDFVDDVIRELAALTPGRSLHIGGDE
                     AHSTSHADYVAFMDKVQPVVAKYGKTVVGWHQLTGAHPAKGAVAQYWGYDKTGAAERQQ
                     VADAARNGTRLILSPADRAYLDMKYDKDTPLGLSWAGYVDVRRSYDWDPGRYLDGAPAG
                     SVLGVEAPLWSETLSTSAHIEYMAFPRLPGIAELGWSPASTHDWDDYKVRLAAQGPRWD
                     ALGINYYRAPEVPWPAR"
     gene            13814..14104
                     /locus_tag="HEP86_RS15350"
                     /old_locus_tag="HEP86_15350"
     CDS             13814..14104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605447.1"
                     /locus_tag="HEP86_RS15350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15350"
                     /product="hypothetical protein"
                     /protein_id="WP_168479225.1"
                     /transl_table=11
                     /translation="MLERRHRSAEAPHEDLVDHLVRSTPLQRGEAARVVLDVLAYFDET
                     TEEFVRRRHRELQSQGLRNEAIFERIGHEMPHRAVAPPELSPRQLRRIVYG"
     gene            14171..16000
                     /gene="glmS"
                     /locus_tag="HEP86_RS15355"
                     /old_locus_tag="HEP86_15355"
     CDS             14171..16000
                     /EC_number="2.6.1.16"
                     /GO_function="GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA]"
                     /GO_process="GO:0006040 - amino sugar metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="glmS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980526.1"
                     /locus_tag="HEP86_RS15355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15355"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="WP_168479226.1"
                     /sec_met_domain="GATase_7 (E-value: 3.3e-15, bitscore:
                     54.9, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIVGYIGKRDVAPLLLEGLQRLEYRGYDSAGIAIHAKGTGKAT
                     GGLKTAKAKGRVRELESRLPKRFAGSTGIAHTRWATHGAPTDENAHPHRDTEGKVAVVH
                     NGIIDNASDLRARLTADGVVFASETDTEVLAHLIGRSTAEKLEERVREALRHIEGTYGI
                     AVLHADFPDRIVVARNGSPVVLGIGEHEMFVSSDVAALVSHTRQVVTLDDGEMATLKAD
                     DYRTYTTEGSRTTSAPETVEYAAESYDLGGHDTYMHKEISEQADAVDRALRGRIDDRFS
                     TVHLGGLNLDAREARGVRRVKILGCGTSYHAGQIGAQMIEELARIPSDAEPASEFRYRN
                     PVVDPDTLYVAVSQSGETYDVLAAVQELKRKGARVLGLVNVVGSAIARETDGGIYVHAG
                     PEVCVVSTKCFTNMVVSFALLALHLGRIRDLSVADGKRIIEGLRKLPAQIDEILKGEED
                     IKKLSAAYADAKSMMFIGRVRGYPVAREASLKLKEVSYIHAEAYPASELKHGPLALIEP
                     AMPTVAIVPDDDLLEKNRAALEEIKARSGRILAVAHQEQEKADHTIVVPKNEPELDPIL
                     MGIPLQLLAYHTALALGRDIDKPRNLAKSVTVE"
     misc_feature    complement(14192..14206)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(16357..16878)
                     /locus_tag="HEP86_RS15360"
                     /old_locus_tag="HEP86_15360"
     CDS             complement(16357..16878)
                     /GO_function="GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105726.1"
                     /locus_tag="HEP86_RS15360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15360"
                     /product="universal stress protein"
                     /protein_id="WP_093646379.1"
                     /transl_table=11
                     /translation="MAGHEIPEPADRKQVADPLADLEAAEKTRHSCDPAFRHGVVVGFD
                     GSMSSERALAYAIGMARRLGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLGLE
                     LACADHLTEVPWILVERGGDICHELEEVGREYEADAIVVGSTHGIVGRIFGSVAGRLAR
                     RAQRPVIVIP"
     misc_feature    17005..17020
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.6"
                     /tool="antismash"
     misc_feature    17007..17021
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.57"
                     /tool="antismash"
     gene            17244..17528
                     /locus_tag="HEP86_RS15365"
                     /old_locus_tag="HEP86_15365"
     CDS             17244..17528
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983274.1"
                     /locus_tag="HEP86_RS15365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15365"
                     /product="hypothetical protein"
                     /protein_id="WP_248001145.1"
                     /transl_table=11
                     /translation="MPLPSDRSPDPVTDVVRWGAFSCALVPFVLIFSGASWAGAAGAAA
                     GLAAVTCACRALLRHSERTAARVRVREVGRHRDRNGRSGTTVHGGGRHS"
     misc_feature    17574..17588
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.26"
                     /tool="antismash"
     misc_feature    17728..17741
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.23"
                     /tool="antismash"
     gene            17899..19173
                     /locus_tag="HEP86_RS15370"
                     /old_locus_tag="HEP86_15370"
     CDS             17899..19173
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046155.1"
                     /locus_tag="HEP86_RS15370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15370"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_248001146.1"
                     /transl_table=11
                     /translation="MSQDSAAVPDAARKLAARRRREIVAVLLFSGGPIFESSIPLSVFG
                     IDRQDAGVPRYRLLVCAGEDAPLRTTGGLELSAPYGLEAISRAGTVVVPAWRSITQAPP
                     PAALDALRRAHEEGARIVGLCTGAFVLAAAGLLDGRPATTHWMYAPTLAKRYPSVHVDP
                     RELFVDDGDVLTSAGTAAGIDLCLHIVRTDHGADAANALARRLVVPPRRTASDMGHQRY
                     LDRSLPEEIGADPLAEVVAWALEHLHEQFDVETLAARAYMSRRTFDRRFRSLTGSAPLQ
                     WLITQRVLQAQRLLETSDYSVDEVAGRCGFRSPVALRGHFRRQLGASPAAYRAAYRARR
                     PQNGDPSPRSDRSVPSGRSGSGRCSARAAGSGTPPPRWPATGWRPRKRPKRANRSRTST
                     PPGCRNPRSAGVRAAPCCPDSGSAP"
     misc_feature    18577..18579
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19184..19801
                     /gene="orn"
                     /locus_tag="HEP86_RS15375"
                     /old_locus_tag="HEP86_15375"
     CDS             19184..19801
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="orn"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542190.1"
                     /locus_tag="HEP86_RS15375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_15375"
                     /product="oligoribonuclease"
                     /protein_id="WP_085928481.1"
                     /transl_table=11
                     /translation="MNDRMVWIDCEMTGLSLANDALIEVAALVTDSELNVLGDGVDVVI
                     RPPAEALGTMPEVVRQMHTASGLLEELDSGTTLEAAEAQVLAYIKQHVPDPGKAPLCGN
                     SVGTDRGFLLRDMPTLESYLHYRIVDVSSVKELARRWFPRAYFNSPDKNGNHRALADIR
                     ESIAELRYYREAVFVPQPGPDSDTAKAIAAKHVLPAEPQSTP"
     tRNA            19964..20039
                     /anticodon=(pos:3423877..3423879,aa:His,seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="HEP86_RS15380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="HEP86_15380"
                     /product="tRNA-His"
     gene            19964..20039
                     /locus_tag="HEP86_RS15380"
                     /old_locus_tag="HEP86_15380"
     misc_feature    20407..20425
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.89"
                     /tool="antismash"
     misc_feature    20572..20585
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(20821..20836)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.91"
                     /tool="antismash"
ORIGIN
        1 tcggctggcc gtgctggacg gcgacgaccc ggcgggtggt gaaggagcgg ccgtcgcgga
       61 tgcggtcgac ggtgtagacg atgggcgcgc cggggtcccc ggggcgcagg aagtacgcgt
      121 gcagggagtg cggcggccgg tcggcgggga ccgtgcgccc ggccgcgacc agggcctggg
      181 cggcgacctg gccgccgaag acccggggta cgaccgaggc gcggctctcg ccccggaaga
      241 tgtcctgctc gatccgctcc agtgcgagca gatcgagcag ggaccggagt gcgtcgttca
      301 cgtgcgcggg gcccttacgg cctagaggcc catggacttg gcgatgatgg acttcatgac
      361 ctcgctggtg ccgccgtaga tgcggttgac gcggttgtcc gcgtagaggc gggcgatggg
      421 gtactcgttc atgaagccgt agccgccgtg cagctggagg cagcggtcaa tgacgcggtg
      481 cgcgacctcg gtgcagaaca gcttggcgga ggcggcctcg gccggggtca gctcgccggc
      541 gtccagcgct tcgagggcgc ggtcggcgac ggcctcggcg gcgtccacct cggcctggca
      601 ggcggccagt tcgaacttgg tgttctggaa ggaggagacc gtcttgccga agatcgtgcg
      661 ctcctgcacg tactccttgg cgaaccggac ggcggccttg gcctgggcgt acgcaccgaa
      721 ggcgatgccc cagcgctcgg aggcgaggtt caggcccagg taggcgaagc ccttgttctc
      781 ctcgcccagc aggtcctcga ccgggacctt gacgtcgacg aaggccagct cggcggtgtc
      841 ggagatcttc aggccgagct tgtccagctt gcggccgacg gagtagccgg cggacttggc
      901 gtccacggcg aagagcgaga tgccgaagcg gcggtcgtcc tcgcgggggg ccgcggtgcg
      961 ggcgcagacg atcacgcggt cggcgtgcac accgccggtg atgaaggtct tggcgccgtt
     1021 gaggacgtag tgcgtgccgt cctccgacag cttcgcggtg gacttcatgc cggcgaggtc
     1081 ggagccggtg cccggctcgg tcatcgccag cgcccacatc tcctcgccgc tgacgaactt
     1141 cggcaggaag cgcttcttct gctcgtcggt ggcgagcatc tggatgtacg ggaggccgag
     1201 cagcacatgc acgccggagc cgccgaaggt gacgcccgcg cgggaggtct cctcgtacat
     1261 cacggcctcg aacttgtgcg agtcgatgcc ggcgccgccg aactcctcgg gcacgcggat
     1321 accgaagacg cccagctcgg cgagcttgta gtagaactcg cgcgggacct ggccggcggc
     1381 gaaccactcg tcgtgcacgg gcacgacctc ggcctcgatg aaggcgcgta tggtctcgcg
     1441 gaacgcctca tgatcctcgt tgaacaccgt acggcgcatt gctacgtcgc ctcctccagg
     1501 tcgccggtcc aagcgcatgg ctaagcgctt gctcagcgaa agctaccggc cagttaccta
     1561 agctgtccag aggtcaacga aaatccgtgc gagcaggcag gcctgcgcct aggcgcccgg
     1621 caccgacgcc gccatcggct cccccgactc cggctccccc gccaccgcgc cgaacgcgcc
     1681 cagcgcgagc cggtgcagca gctccgccat ctccgtacgg cccgggaggg cgcccgggcg
     1741 gccgaggtgc ggggtggagt tgagcaggcc gaagacggcg tgcacggcgg cgcgggcccg
     1801 ggactcggag gggcccgggt ggacccggcg gacgacctcc acccacagct ccacgtactg
     1861 ccgctggagc tggcggaccc gcttgcggtc ggcctcccgc agccggtcca gctcccggtc
     1921 gtgcagggtg atcagcggcc ggtcgtccag cgcgaagtcg atatggccgt cgatcagcgc
     1981 gtccagcacc gcctcggggc tgccgccgcc ctccgtgacc cgcatccggc cgcccgcgag
     2041 cagccgctca ctgatcccga ccagcagctc ggcgagcatc gcgtccttgc cggcgaagtg
     2101 ccggtagagg cccggaccgg agatgcccac ggccgcccct atctcgtcca cgccgacgcc
     2161 gtggaagccg cgctccgcga agagccgggc ggcctccttg aggatctgct cgcggcggct
     2221 ggtcggggtg gcgggctgcg cattactcat gccgtcgatt gtagacagcc gggttagtgc
     2281 tcgttaacct gaaggcagtg acgttaacgc ccattaaccc ggatggaccg gccgccgcgg
     2341 accgcggcac cgggacaggt gatcgagcaa gggggctcgt aacgatggag caggcaccgg
     2401 tgctggggag taccgccgat ccggcgtccg actcctggcg ggccaatgag gccgcgcacc
     2461 gcgagttggc cgcacagctg cgcgagaagc tcgcggcggc ccggctgggc ggcggcgaga
     2521 aggccagggc gcggcacacc gcacgcggca agctgctgcc ccgcgaccgg gtggacgcgc
     2581 tgctggaccc cggctcgccg ttcctggagc tggcgccgct ggccgcggac gggatgtacg
     2641 gcggggccgc cccggccgcg ggcgtgatcg ccgggatcgg ccgggtctcc ggccgggaga
     2701 cggtgatcgt cgccaatgac gccacggtca agggcggcac gtactacccg atgacggtca
     2761 agaagcatct ccgggcgcag gagatcgccc tggagaaccg tctcccctgt ctttacctcg
     2821 tcgactccgg cggcgccttc ctgccgatgc aggacgaggt cttccccgac cgggagcact
     2881 tcgggcggat cttctacaac caggcgcgga tgtcgggtgc ggggattccg cagatcgccg
     2941 cggtgctggg ctcgtgcacg gccggtggcg cctacgtccc ggccatgagc gacgaggccg
     3001 tgatcgtccg caaccagggc acgatcttcc tgggcgggcc gccgctggtg aaggccgcca
     3061 ccggtgaggt ggtcaccgcc gaggagctgg gcggcggcga ggtgcacgcg aagacctccg
     3121 gcgtcaccga ccatctcgcc gaggacgacg cccatgcgct gcgcctggtg cgcaccatcg
     3181 tcggcaccct cggcgagcgc gcgccgctcc cgtggaccgt gcggaccgtc gaggagccca
     3241 aggcggaccc ggccgggctg tacggggcgg tgcccgcgga ctcccgtacg ccctatgacg
     3301 tccgggaggt gatcgcccgc ctcgtggacg gctcgcgctt cgcggagttc aaggcggagt
     3361 acgggacgac gctggtcacc ggcttcgccc atatccacgg ccacccggtc ggcatcgtcg
     3421 ccaacaacgg catcctgttc tccgaatccg cccagaaggg cgcccacttc atcgagctgt
     3481 gcgaccagcg cggtatcccg ctgctgttcc tgcagaacat ctccggcttc atggtggggc
     3541 gctcgtacga ggccggcggg atcgccaagc acggcgcgaa gatggtgacg gcggtggcct
     3601 gcacccgcgt gcccaagctg acggtcgtca tcggcggctc ctacggggcg ggcaactact
     3661 ccatgtgcgg ccgggcctat tcgccgcgct tcctgtggat gtggccgaac gccaagatct
     3721 cggtgatggg cggcgaacag gccgcctccg tcctcgccac cgtcaagcgc gaccagctgg
     3781 aggcgcacgg cgaggagtgg agcgccgagg acgaggccgc cttcaaggcg ccggtccgcg
     3841 agcagtacga gacccagggc agcgcctact acgcgagcgc gcgactgtgg gacgacggtg
     3901 tgatcgaccc gctggagacc cggcaggtgc tggggctggc gctgacggcc tgtgccaacg
     3961 cgccgctccc cgagaaggac agcaccgcgc ccggctacgg cgtcttccgg atgtgagagg
     4021 gatgtcccca gcaatggtca ccaacttcga caccgtgctc atcgccaacc gcggcgagat
     4081 cgcggtccgt gtcatccgca cgctgcgcgc cctcggcatc cgctcggtcg ccgtctacag
     4141 cgacgcggac gccgacgccc gccatgtccg ggaggccgac acggccgtac ggatcggtcc
     4201 ggcgccggcc gccgagagct atctgtccgt ggagcggctg ctggaggcgg ccgcccgtac
     4261 gggcgcccag gcggtccacc cgggctacgg cttcctcgcc gagaacgccg ccttcgcccg
     4321 tgccgtcacg gacgccgggc tggtcttcat cgggccgtcc gccgacgcca tcgagctgat
     4381 gggcgacaag atccgcgcca aggagacggt gcgggaggcc ggggtcccgg tcgtccccgg
     4441 ctcctcgggc agcgggctgg acgacggtca actggccgcc gcggcccgcg agatcggcat
     4501 gccggtgctg ctcaagccgt ccgcgggcgg cggtggcaag ggcatgcggc tggtccgcga
     4561 cgagacgctg ctggccgacg agatcgcgtc cgcccgccgg gaggcccgct cctccttcgg
     4621 cgatgacacc ctgctcgtcg agcgctggat cgaccggccc cggcacatcg agatccaggt
     4681 gctggcggac ggccacggca acgtcatcca tctcggcgag cgcgagtgct ccctccagcg
     4741 ccgccaccag aaggtcatcg aggaggcccc ctcggtcctg ctggacgagg ccacccgcgc
     4801 cgcgatgggc gaggcggccg tgcaggcggc ccgctcctgc ggctaccgcg gcgccggcac
     4861 cgtcgagttc atcgtcccgg gcaaggaccc ggcctcctac tacttcatgg agatgaacac
     4921 ccgcctccag gtggagcacc cggtcaccga gctgatcacg gggctcgacc tggtggagtg
     4981 gcagctgcgg gtcgcggccg gcgaggtgct cccgtacgcc caggaggaca tcaccctcac
     5041 cgggcacgcc atcgaggcgc ggatctgcgc cgaggacccg gcccgcgact tcctgccgac
     5101 cggcggcacg gtgctggcgc tgcacgagcc gcagggcggc gggacccgca ccgactccgg
     5161 gctcctggag ggcggggagg tcggcagccg ctacgacccg atgctgtcca aggtgatcgc
     5221 ctacggtccg gaccgggcga gcgccctgcg ccggctccgg gccgcgctgg ccgagaccgt
     5281 caccctcggc gtcaccacca acgccgggtt cctgcggcgg ctgctggccc acccggacgt
     5341 ggtctccggc gagctggaca ccggcctggt ggagcgggag gcggccggtc tggtcgacgg
     5401 cacggtgccc gaggaggtgt acgcggcggc cgcggcggtg cggcaggccg ccctggagcc
     5461 ggcggtggcc gacggcggct ggcgcgaccc gttcgccgca ccgaacggct tccggctcgg
     5521 cggcgagccc gcaccggtcc gccactggct gcggatcccg ggacacgacc cggtgccgca
     5581 cgacgtacgc cccggcgccc cggccggaca gctggagccg ggccgcgtac gggtcaccgt
     5641 cgacggggtg ctgcacacct tccaccacag cggcgactgg ctcggccggg acggcgactc
     5701 ctggcaggtg accagccacg acccggtggc cgcggcgctg cgcggggccg ccggggcgca
     5761 cggcgcggac accctcgccg ccccgatgcc cggcaccgtc accgtcgtca aggtcgccgt
     5821 cggcgacgaa gtgaccgcgg gccagggcct gctggtggtg gaggcgatga agatggagca
     5881 cgtcatctcc gcgccgcacg ccgggaccgt caccgaactc gacgtcaccg cgggctcgac
     5941 cgtcgccatg gaccagatcc tggccgtggt cgccccgcac gagagccccg acgaggccgc
     6001 cgcgtccccg gccgcacccg agaacgggca ggagagcgcc tgatgaccgc acccggactg
     6061 ccgatggagg tccccgcgga ggggctgccc acccgcgtac ggatccatga ggtcggcgcg
     6121 cgcgacggcc tgcagaacga gcggaccgtc gtccccacgg aggtcaaggc ggagttcatc
     6181 caccggctcg ccgccgcggg cctgccgacc gtggaggcca ccagcttcgt ccaccccaag
     6241 tgggtgcccc aactcgccga cgccgagcag ctgttcccgc tgctggacga tctcgatccg
     6301 cagcggctgc cggtgctggt ccccaacgag cgtgggctgg accgggcgct ggcgctgggc
     6361 gcccgccgga tcgcggtgtt cggcagcgcc accgagtcgt tcgccaaggc caacctcaac
     6421 cgcacggtcg acgaggcgct ggcgatgttc gcgccggtca tcgcgcgggc caagggcgcc
     6481 cgggtggagg tccgcggcta tctctcgatg tgcttcggcg acccctggga ggggccggtg
     6541 ccggtcgcgc agaccgtccg ggtctgccgg gcgctgctcg acctgggctg cgacgaactg
     6601 agcctgggcg acaccatcgg ggtggccacc cccggccatg tgcagaccct gctggccgcc
     6661 ctcaacgagg ccggggtgcc cacctcccgt atcggcgtgc acttccacga cacctacggg
     6721 caggccctcg ccaacacctt cgccgcgctc cagcacggca tcaccaccat cgacgcctcg
     6781 gcgggcggcc tcggcggctg cccgtatgcc aagagcgcca ccggaaacct cgccaccgaa
     6841 gacctcgtgt ggatgctgca cggcctcggc atcgagaccg gggtcgacct ggaccgtctg
     6901 accgccacca gcgtgtggat ggccgaggcc ctgggccggc cgagcccctc gcgtaccctc
     6961 cgtgccctct cccacaagga gtgaccctca tgtccctgga ccaccgcctg cccgacgagc
     7021 tggaagaact ccggcgcacg gtcgaggcgt tcgcacacga cgtcgtcgcc cccaagatcg
     7081 gcgagtacta cgagcagcac gcgttcccgt acgagatcgt gcaggaaatg ggccggatgg
     7141 gcctgttcgg cctgccgttc cccgaggagt acggcgggat gggcggcgac tacctcgccc
     7201 tcggcatcgc cctggaggag ctggcccggg tcgactcctc ggtggccatc accctggagg
     7261 cgggcgtctc cctgggcgcc atgcccgtct accacttcgg tacggaggag cagaagcgcg
     7321 cgtggctgcc caagctgtgc agcggtgaga tgctcggcgc cttcggcctc accgaaccgg
     7381 acggcggctc ggacgccggc accaccgccg tgcgcgacgg cggggactgg gtgatcaacg
     7441 gcagcaagtg cttcatcacc aactccggta cggacatcac cggcctggtc acggtcaccg
     7501 ccgtcaccgg ccgcaaggac gacggctccc cgctgatctc ctcgatcatc gtgccctccg
     7561 gcaccccggg cttcaccgtc ggcgcgccgt actccaaggt cggctggaac gcctccgaca
     7621 cccgcgagct gtcgttctcc gacgtccggg tcccggccgc caacctgctg ggcgaggagg
     7681 gccgcggcta cgcccagttc ctgcggatcc tcgacgaggg ccggatcgcc atcgcggcgc
     7741 tggccaccgg cctggcgcag ggctgtgtgg acgagtcggt gcgctacgcc aaggagcggc
     7801 acgccttcgg ccgcgccatc ggcaccaacc aggcgatcca gttcaagctc gccgacatgg
     7861 agatgcgcgc gcacacctcc cggctgtcct ggcgccatgc cgcgtccaag ctggtgcacg
     7921 gcgagccctt caagaaggag gccgcgctcg ccaagctcta ctcgtccgag atcgccgtgg
     7981 acaacgcccg cgaggccacc cagatccacg gcggctacgg cttcatgaac gagtacccgg
     8041 tcgcccggat gtggcgggac gccaagatcc tggagatcgg cgagggcacc agcgaggtcc
     8101 agcggatgct gatcgcccgg gagttgggcg tggtctagag cgtccttccg ggcatggccc
     8161 ggtgacgtga gaggtgggcg gtccggtcgc atcaggcgac cgggccgccg tttttctgcg
     8221 ccgggtgttc ccgcccgccc cggcgcccgc cggcgctgcc cccgtccgac cgctcgtccg
     8281 cccggcgctc ggccgccgct gtgcgcggcc gcgcctgtac cccggtgcgt ccggagcatg
     8341 cggcggcggg agggcgtgcg ggcgcacaac catgatccgt ctgcaacgcc tggaggttta
     8401 tgcctcttgg atgcgaggtc gccccctttc acgccgtacc gccacagccg tccctcctgt
     8461 ttggcttgct cctgcacgcg gccgctttgc tcaccaccgg ccgctttgct cacgtctgtt
     8521 catgtcccgg gagggaaagt gtccgtaccg gacggcgtca ccggttccac caccgaagag
     8581 cccgctctcg caccacccgc cgacagcgcg cccaccagcc tcggcaccca ggccgcgcgc
     8641 caactggcga ccaccaccaa gtccgagccc cagatgcagg ccatcacctc gcggtggctg
     8701 ctgaagacgc tgccctgggt ggacgtcaag ggcggcgcct accgggtcaa ccggcgcctc
     8761 cagctccgcg tcggccgggg ccgggtccag ttcgagcaga acggcgcgga cgacatcaga
     8821 gtcatcccgc agaccctcac cgaactgccc gccctgcgcg gctaccccga caccgaggtc
     8881 ctcaaggagc tggccggccg cttccgggtc cgcgaggtcc gggccggcca ggtgctcttc
     8941 gaggccgggc agcccaccac cgaggcgtat ctcgtcgtcc acggccgttt cgcccgctac
     9001 acggccggca aatacggcga cgaggaggtc atcggcgtcg tcacggacgg cgaccagatg
     9061 ggggacgagg cgatcggccg gcccgacccg cggtggctga gctcggtccg ggccgagacg
     9121 gcgggcgtgc tgatggtgct gccctgggac gtggtccggg agttcaccga ccgggtgccg
     9181 tccctggccg cccacctgac ggcgtacgcg gagcagcagc agcgccccat gaaccgcaag
     9241 ggcgaggcgg aggtgccggt gcgggcgggg cacgtcggcg agccgacgct gtcgtccggc
     9301 ttcgtcgact acgacctcgc cccgcgcgag tacgagctct ccctgaccca gaccgtgctg
     9361 cgggtccaca gccgggtcgc cgatctctac aacgacccca tggaccagac gcagcagcaa
     9421 ctccggctca ccgtggagga gatccgcgag cgccaggagt gggagatggt caacaaccgg
     9481 gagttcggcc tgctgcacaa cgccgactac ggccagcgga tcagcaccta caccggcccg
     9541 cccacccccg acgacatgga cgagctgttg tccatgcgcc gcaagacccg gctgttcctg
     9601 gcccatccga aggcgatcgc cgccttcttc cggcagtgca acaagcgcgg tctggtgccg
     9661 ggcacggcga acgtcgacgg gcacgaggtg cccgcctggc gcggggtccc gatcttcccc
     9721 tgcggcaaga tcccgatcag cgacagccac accagcagca tcctcgcgct gcgtaccggc
     9781 gaggcggacc agggagtcgt cggcctgcac cagaccggca tccccgagga gtaccagccc
     9841 ggtctgaacg tccggttcat gggcatcgac ccgtccgcgg tcatcaacta cctcgtcacc
     9901 gcctactact cgctggccat cctcgtgccc gacgccgtcg gagtcctgga gaacgtccag
     9961 atcggccgga gtgccgactg accaggtgga gtccctcacc atgagcaccc ccccgaacac
    10021 cgccgccacg tggtcgatgc ccggcccgcc gaacctcgcc cgcactctgc ggacccgccg
    10081 ccccggaggc gccgtccccg ggctgcggta ccggcccgcc gcccccgccg acccggagaa
    10141 ggccgcggag atcgaccgca ggctggaggc ctgggcccgc cggctggacc tgttccccgc
    10201 gcagtggacc ggggacttca cggagttcca gttcggccgg gcggtcgtcc tccagcatcc
    10261 cggcgccgcc gacctcgaac gcctcaccgc cgcgggcaag ctgctgctgg ccgagaacat
    10321 cgtcgacaac tgctactgcg aggaggacga gggcaagggc ggcgcgcacc gcggcctggg
    10381 cggccgcctg atcatggccc agtcggccct cgatccgctg cacgccaccc ccgagctgga
    10441 ggaggagtgg cgccacggtg tgcaggccga cgggccgctg cgctcgtacc actgggcgct
    10501 gaaggactac gcggcgctcg ccacccccag ccagaccgac cggttcgtcc aggacatcgc
    10561 ccggctgcac ctcggctatc tcgccgaggc cgcctgggcg gagacccggc atgcgccgcg
    10621 ggtctgggag tacctcgtca tgcggcagtt caacaacttc cgcccctgtc tgtccatcgt
    10681 cgacgcggtg gacggctacg aactgcccga ggcgctctac gcccgccccg aggtccagcg
    10741 ggtcaccgct ctggcgtgca acgccacgac catcgtcaac gacctgtact ccttcaccag
    10801 ggagctggcg agtgacccgc accatctgaa cctgccgcaa gtggtggccg ccaacgacca
    10861 acgcggcctg aaggacgcct acttgaagag cgtcgagatc cacaaccagg tcatggcggc
    10921 gttcgagacg gagtcggccc cgctgtcggc cacctcgccc ctcctcgaac gctacgtccg
    10981 gagcctcgcc gactgggtgt ccggcaacca cgagtggcac gccaccaaca ccgaccgcta
    11041 ccagctgccc aactactggt agaccgatcc gcgcaccaga gcaaggagcc accgttgacc
    11101 atcgctcacg ccgacaccgc ccgcaccccg gtgccgaccc agtccacgta ccagtcccgg
    11161 gtcgcggact actggaacgc cgaggaaaac ccggtcaacc tcgaactcgg caagatcgac
    11221 gacctgtacc accatcacta cggcatcggg gacgccgacc ggtcggtgct gaacgagccg
    11281 gaccccggcc ggcgccggga ccgggtcacc ggtgaactgc accgcctgga acacgcccag
    11341 gccgagctgc tcgcctccca cctgggcgac gtctccccca ccgaccgcgt cttcgacgcc
    11401 gggtgcggcc gcggcggcgg cagcgtggtc gcgaatctgc gctacggctg ccacaccgac
    11461 ggcgccacca tctccgccaa gcaggccgat ttcgccaacg cgcaggcccg caagcgcggt
    11521 gtcgacgaca aggtgcgcta ccaccaccgc aatatgctcg acaccggctt caccaccggc
    11581 gcgtacgcgg cgtcctggaa caacgagtcg agcatgtacg tcgagctgga cctgctgttc
    11641 gccgagcacg cccggctgct gcggcgcggt ggccgctatg tggtgatcac cggctgctac
    11701 aacgacgcct acgggcgcgc ctcccgcgag gtgtccctca tcaacgccca ctacatctgc
    11761 gatatccacc cgcggtcggc gtacttccgc gccatggccc gcaaccggct ggtccccgtg
    11821 cacgtcgagg acctgacggc ggccgcgctc ccgtactggg aactgcgccg ggaggccgac
    11881 cacctggtca cggggatcga ggacaccttc ctgaccgcgt accgcaacgg cagcttccag
    11941 tacctgatga tcgccgccga ccgggtatga gaactccgcg gtccgtgccg ggcgtcccac
    12001 gacgcccggc acggccgtgt cagcgcgccg gccagggcac ctccggcgcg cggtagtagt
    12061 tgatgcccag cgcgtcccag cgcggcccct gggcggccag ccggaccttg tagtcgtccc
    12121 agtcatgggt gctcgccggg gaccagccca gctcggcgat gccgggcagc cgcgggaagg
    12181 ccatgtactc gatgtgcgcg gaggtggaga gcgtctcgga ccacaggggc gcctccacgc
    12241 cgaggacgga gcccgcgggc gcgccgtcga ggtagcggcc cgggtcccag tcgtaggagc
    12301 gcctgacgtc cacatagccc gcccaggaca ggcccagcgg tgtgtccttg tcgtacttca
    12361 tgtcgaggta ggcacggtcg gcgggcgaga ggatcagccg ggtgccgttc cgggcggcgt
    12421 cggcgacctg ctgccgctcc gccgcgccgg tcttgtcgta gccccagtac tgcgcgacgg
    12481 cgcccttggc cgggtgcgcc ccggtcagct ggtgccagcc gaccacggtc ttgccgtatt
    12541 tggcgaccac cggctgcacc ttgtccatga aggccacata gtccgcatgg ctggtggagt
    12601 gcgcctcgtc gcccccgatg tgcagggagc ggccgggtgt cagggccgcg agctcgcgga
    12661 tgacgtcgtc cacgaagtcg taggtctcct gcttgggcac gcacagggag ctgaagccga
    12721 cctgggtgcc ggtatagagc ggcggtgcct ggccgttgca gttgagcggg gcgtaggagg
    12781 ccagcgcggc gttggtgtgg cccggcatgt cgatctccgg gacgacggtc agatagcggg
    12841 ccgcggcgta gcggacgatc tcgcggtagt cgtccttggt gtagtagccg ccgcgtccgc
    12901 cgccgacctg ggtggagccg ccgtaggtcg ccaggcgcgg ccaggacttg atggcgatcc
    12961 gccagccctg gtcgtccgag agatgcagat gcagcttgtt gatcttgtac atggcgagct
    13021 ggtcgatgta ccgcttgacc tgcgccacgg tgaagaagtg ccgggagaca tcgagcatcg
    13081 cgccccggta gccgtagcgc ggggagtcgg cgatggtgcc cccggcgatc cgccagggcc
    13141 cgcgccgggc ccgctgctgc tccaggtcgg cgggcagcag ctggcgcagg gtctgcacgc
    13201 cgtggaagag cccggcgggg cgggcggcgc tgagggtgac cgcacggccg tcggaggtca
    13261 gccggtagcc ctcggcgccc agcccgccgg tgccgctgcc gccgagccgc aggacgatgc
    13321 cgtcccggcc gtccttggtc gtgacgggga gggcgaggcc ggtggcgggc cgcagcagcc
    13381 ccgccagata gccggcgatc cgcttggcct ccccggagcc gccgggcacc cggatccggg
    13441 tgcggtcacc gagggtgtac gcctccccgc cgccgcgtac ggacgcgggc gccgggatca
    13501 cccggtccag cggggtggcg gcccggggag cggccccggc ggcgccctgc ggcggtacgg
    13561 cggcggtccc cagccccgcc gccgcgacca gcagcagcga gaacagcagt ctgcgtcgtc
    13621 tcatcgacgg tcccttcggc gaacctcgtg catggcgtgg tgcatggcat ggagcgaccg
    13681 aacggtgacc atgcgtaccg tgagcctcga ttccggtcaa ggttcagacc actttcgagc
    13741 ccccaaatcg gggtcgtgcc cgatagcggg cagatttctt gccattcccc gcgccgcccc
    13801 gcagtatcta cgggtgctcg aacgccgtca ccgcagcgct gaagcgccgc acgaagacct
    13861 ggtcgaccac ctggtgcgca gcacaccgct tcagcgcggt gaggccgccc gggtggtgct
    13921 ggacgtgctc gcgtacttcg acgagaccac ggaggaattc gtccgccgcc gccatcggga
    13981 gctccagtcc cagggactgc gcaacgaggc gatcttcgaa cggatcggcc acgagatgcc
    14041 gcaccgcgcc gtggccccgc cggagctctc gccccgccag ctgcgccgca tcgtctacgg
    14101 ctgacggcca cgcccgggac gccgggcagc acgcaccatt gccacaacgc tttactggga
    14161 gggtcactgt atgtgcggga tcgttggata catcggcaaa cgtgatgtcg ccccgctgct
    14221 cctcgagggc cttcagcgcc tggagtaccg gggttacgac tccgcgggca tcgccatcca
    14281 cgccaagggc accggcaagg ccacgggcgg cctgaagacc gccaaggcca agggccgggt
    14341 ccgtgagctg gagtcccggc tgcccaagcg cttcgcgggc tccaccggca tcgcgcacac
    14401 ccgctgggcc acccacggcg cgccgaccga cgagaacgcc cacccgcacc gggacaccga
    14461 gggcaaggtc gcggtcgtcc acaacggcat catcgacaac gcctccgacc tgcgcgcccg
    14521 gctgaccgcc gacggcgtcg tcttcgcttc cgagaccgac accgaggtgc tggcccacct
    14581 catcggccgc tccacggccg agaagctgga ggagcgggtc cgcgaggcgc tgcggcacat
    14641 cgagggcacc tacggcatcg ccgtgctgca cgccgacttc cccgaccgca tcgtggtggc
    14701 ccgcaacggc tccccggtcg tcctcggcat cggcgagcac gagatgttcg tctcctccga
    14761 cgtcgccgcg ctggtctcgc acacccgcca ggtcgtcacc ctcgacgacg gcgagatggc
    14821 caccctcaag gccgacgact accgcacgta caccaccgag ggctcgcgga ccacgtccgc
    14881 tccggagacc gtcgagtacg cggccgagtc gtacgacctg ggcggccacg acacgtacat
    14941 gcacaaggag atctccgagc aggcggacgc ggtggaccgc gcgctgcgcg gccggatcga
    15001 cgaccgtttc tccacggtgc acctcggcgg cctgaacctc gacgcccgtg aggcgcgcgg
    15061 ggtgcgccgg gtgaagatcc tgggctgcgg cacctcgtac cacgcgggcc agatcggcgc
    15121 gcagatgatc gaggagctgg cccgtatccc ctcggatgcc gagccggcct ccgagttccg
    15181 ctaccgcaac ccggtcgtgg accccgacac gctgtacgtg gcggtctccc agtccggcga
    15241 gacctacgac gtgctggcgg ccgtccagga gctcaagcgc aagggcgccc gggtcctggg
    15301 cctggtgaac gtggtcggct cggcgatcgc ccgggagacc gacggcggca tctacgtgca
    15361 cgccggcccc gaggtctgcg tggtctccac caagtgcttc accaacatgg tggtgtcctt
    15421 cgcgctgctc gccctgcacc tgggccggat ccgtgacctg tcggtcgcgg acggcaagcg
    15481 gatcatcgag ggcctgcgca agctgcccgc gcagatcgac gagatcctca agggcgagga
    15541 ggacatcaag aagctgtccg ccgcctacgc ggacgccaag tcgatgatgt tcatcggccg
    15601 ggtgcgcggc taccccgtgg cccgtgaggc ctccctgaag ctcaaggagg tctcctacat
    15661 ccacgccgag gcctacccgg cctccgagct caagcacggc ccgctggccc tcatcgagcc
    15721 cgcgatgccg accgtggcga tcgtcccgga cgacgacctg ctggagaaga accgcgccgc
    15781 gctggaggag atcaaggccc gcagcggccg catcctggcc gtcgcgcacc aggagcagga
    15841 gaaggccgac cacaccatcg tcgtgccgaa gaacgagccc gagctggacc cgatcctgat
    15901 gggcatcccg ctccaactgc tcgcctacca cacggccttg gccctcggcc gggacatcga
    15961 caagccgcgc aacctggcga agtccgtcac ggtggagtaa cccgcccagg cggctccgcg
    16021 cgtgccacca gcgcgcggag ccgccgcctc ttctcgccgg cgtcgcccat acgccggcgg
    16081 gatgccaccg ccccgggagc cgtcacctcc cggccggcag cacgaagttg ccgtgcgcgc
    16141 ggccgccggg cccgtgatgc ggcgcgccca cgtgacgttt tcctacccct cgcggacgcc
    16201 cgattcacct tgccgcggca gcggaagtgc ggctgcgcac aatcctcatg acgcccccgc
    16261 acctgtgtgc atgacgggga gaaagatcgc gtgaagaggc ggcgcggcac ggggagttga
    16321 gcgcccacca cgggacgggg ccgcaccgag ggtgcgtcag ggaatcacga tcaccgggcg
    16381 ctgtgcccgg cgggccagcc ggccggccac cgagccgaag atccggccga cgatgccgtg
    16441 cgtggagccg accacgatcg cgtcggcctc gtactcccgg ccgacctcct ccagctcgtg
    16501 gcagatgtcc ccgccgcgct cgacgaggat ccagggcacc tcggtgagat gatccgcgca
    16561 ggccagctcc aggccgagca cttcggtgcg gtgatccggc acgtccacga agacgggggg
    16621 ctcacagccc gcccagacgg tcgtcggcag ccggttggcc acatggacga tgatcaaacc
    16681 ggagcccagg cgccgggcca taccgattgc atacgccaac gcgcgctcgc tcgacatgga
    16741 gccgtcgaag ccgaccacga cgccgtgccg gaaggcgggg tcgcaggagt ggcgtgtctt
    16801 ttccgccgct tcgaggtccg ccaggggatc ggcgacctgc ttgcggtccg cgggttcggg
    16861 gatttcgtga ccggccattg gtgtctcggc gaggacgtcc tcttgcggag gggcgaacgg
    16921 ggaacggcga ttgacttgat ccggcagttg actgagctga ctcgcccgaa gtgcgggagc
    16981 catagttcaa agaggaacga tacgactggg aatcatcttc ccaacccgat accccaagag
    17041 tacggcgcca ctcccccgct gcccagagcc cgccacggac gcgcagcgcc cgtgcgaggt
    17101 gagtggggcc tcgaacgttc cccggagcat gccggagcgt ggcgcggatg gcaatgcccc
    17161 ggcctgcccc cgtacgtacc cctcgcggtg acccatgatc gtcggccgcg ttgtagtagc
    17221 agcccgtccg aggggagtgc gcggtgccgt tgccgtccga cagatcaccc gacccagtga
    17281 ccgatgtggt gcgctggggc gcgttcagct gcgccctggt gcccttcgtc ctgatcttca
    17341 gcggcgcctc ctgggccggt gcggccggtg ccgccgccgg tctggccgcg gtgacctgcg
    17401 cctgtcgcgc gctgttgcgg cattccgaac ggaccgccgc ccgggtccgc gtgcgcgagg
    17461 tcggacggca ccgggacaga aacggacgtt cagggacaac agtgcacggg ggcggtcggc
    17521 actcctaagg gcgtacgccg gtcgattgag gcgcctgcaa gtctgcgcgc gaccgttttc
    17581 agccaacttc cggccgaggt ccacaccttg cccgtggcac ccctcaaccc tggtgtgagc
    17641 agggaggaaa ggaccgctgg gcatggttgt gccctactgc gaacgggcag agccgagacg
    17701 cgtacttccc atgtaggccc gacgagtgga acgcttcgtg atcgaatgct tcgcgccaag
    17761 ttgccatatc gacataccag cgggtggtga acttggcact ccatcctcac ggaacacagt
    17821 agattcgatc ttggtagcaa tggcggggga actgtgcagg accgagaggg cgagacgacc
    17881 gaggggggct taagtgccat gagccaggac tccgctgccg taccagatgc cgcacgcaag
    17941 ctcgccgccc gacgacgccg cgaaatagtc gcggtgctcc tcttcagcgg cggccccatt
    18001 ttcgagagct ccattccgct ctcggtcttc ggcatcgacc gacaggacgc aggcgttccg
    18061 cggtaccggc tgcttgtgtg cgcgggcgaa gatgcgcctt tgcgcacgac cggggggctc
    18121 gaactatccg ccccctacgg gctggaggcg atctcccgtg ccgggacggt cgtcgtaccg
    18181 gcctggcgat ccatcaccca ggccccgccg cccgccgcgc tcgacgcgct gcgccgcgcg
    18241 catgaagaag gggccagaat cgtcgggctg tgcacggggg cgttcgtcct cgccgcggcc
    18301 ggactgctcg acggccgccc ggccaccact cactggatgt acgcaccgac gctcgccaag
    18361 cgttacccgt ccgtccatgt ggatccccgc gagctcttcg tcgacgacgg cgatgtactc
    18421 acgtccgcgg gaacggcggc cggtatcgac ctgtgtctgc acatcgtgcg caccgaccac
    18481 ggcgcggacg ccgcgaacgc gctggcccgc cggctcgtcg tgccgccccg ccggaccgcg
    18541 tccgacatgg ggcaccagcg ctacctggac aggtcattac ctgaagagat cggcgccgac
    18601 ccgctcgccg aggtcgtcgc ctgggcgctg gagcatctcc acgagcagtt cgacgtggag
    18661 acgctggccg cgcgtgcgta catgagccgg cgcaccttcg accggcgctt ccgctcgctg
    18721 accggcagcg ccccgctcca gtggctgatc acccagcggg tgctccaggc ccagcggctg
    18781 ctggagacct ccgactattc ggtggacgag gtcgccgggc gctgcggctt ccgctcgccg
    18841 gtcgccctgc gcggccactt ccggcggcag ctgggcgcct cgcccgcggc ctaccgtgcg
    18901 gcctaccgcg cgcgccggcc gcagaacggg gacccgagcc cgcgctcaga ccggagcgtg
    18961 ccgagcggcc ggagcgggag cgggcgatgc tcggcgcggg cagcggggag cggtacgccg
    19021 ccgccgcgct ggccggccac gggctggcga ccgcggaagc ggccgaagcg ggcaaaccgc
    19081 agtcggacgt ctacgcctcc cggctgccgg aatccccggt cggccggggt ccgggccgcc
    19141 ccgtgctgcc cggacagcgg gagcgccccg tagggtgaga tgtatgaacg atcgcatggt
    19201 gtggatcgac tgcgagatga ccggactctc gctggcgaat gacgcgctca tcgaggtggc
    19261 cgccctggtc accgactcgg agctgaatgt gctgggcgac ggggtggatg tggtgatccg
    19321 ccctccggcc gaggcgctcg gcaccatgcc ggaggtggtg cgccagatgc acaccgcctc
    19381 cgggctgctg gaggagctcg acagcggtac gacgctggag gcggcggagg cgcaggtgct
    19441 tgcgtacatc aagcagcatg tgccggaccc ggggaaggcg ccgctgtgcg gcaattccgt
    19501 gggcaccgac cgtggcttcc tgctgcgcga catgccgacg ctggagagct acctccacta
    19561 ccggatcgtc gatgtctcgt ccgtgaagga actggcccgg cgctggttcc cgcgggccta
    19621 cttcaacagt ccggacaaaa acggcaacca ccgggcgctg gcggacatcc gtgaatccat
    19681 cgcggaactg cgctactacc gggaggcggt cttcgtgccg cagcccggcc ccgactcgga
    19741 caccgcgaag gccatcgccg ccaagcacgt ccttcccgct gagccgcagt ccacgccgta
    19801 gcgagccaca gggcgcgtgt cgtgcgggtg cccacgggtc caccgcgacc cgcacgacac
    19861 gccctcgggc ccgggataca aaacctgggc gcgagcaccc ctccggaccc tgtacacttt
    19921 tcctcagccg gtggggaaaa agaaccacac agcaccggtc atggtgggta tagctcagct
    19981 ggtagagcac ctggttgtgg tccaggaagt cgcgggttca agtcccgtta ctcaccccac
    20041 ttcaaggccc ccgacctcag gtcgggggcc ttggcgtttg tccggtgccg gccggccgcc
    20101 catataaggg ggcggggccg ggggccgggg ccgggggccg gggcgaggat ggtgccggtg
    20161 atcgcactcg ggcgccgagg gctcgcgatg atcttcacga ggttgccgag agtgccgcct
    20221 gcctcacgcg gccgatcgtg cgcatgacag ccccgagggc gcgccgtagg gagaagacgg
    20281 cggggcgcag cgggtagggg gagcccgctg cgccccggcc tggggacgga cggtccgtgg
    20341 gggcggaccg ccggtggggg tcagcccttg tacgcgccga aggccctggt gaagtccagc
    20401 ggcttctgct cgatggaact acaggtcggc tgcgcggtgt tgccggtgcc gccggggcag
    20461 gcctggtccc gggtcgagga ccacatcgac agccaggcca ggtgcttggt ccgggcgaac
    20521 ttcaccagct gggtggcgtc gccgcggcgg aagacctcgt tctggacgtc gttgacgccg
    20581 atcatcgggg tcacggccac ggtcttccag gcggccgcgt cgctcaggcc gagggccttc
    20641 ttgagctggc cctgggtggc ggtggcggcc tgggtggcgt aggtgcccat gtcgccgctg
    20701 taggcggggc cgtagtccat cgccatgacg ttgacggcgg agatcttgac gccgttcttc
    20761 ttggcgtcgg cgagcaggtt caccccgtcc tgggtcaggc cctcgggcat gaccggcagg
    20821 gtgaaggaga cgtcgaggcc ggggtgcttc ttctggagcc ggttgatggc ctgggcgcgg
    20881 cgggtgttgg cggcggtgtc cggcagggcg ccgccctcga tgtcgaagtc ggccttggtg
    20941 agcttgaacc ggtcgatgac cttgccgtag gcggcggcca gctcgcccgt ggagccgcag
    21001 gccactccga gctcggagcc gttggcgccg ccgaaggaga cccggacgtc gccgccggcc
    21061 gc
//
