LOCUS       NZ_CP050976            25945 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1141996
            Orig. end                         :: 1167941
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25945
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="RiPP-like"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25945
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20981
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20981
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10981](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10981)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    109..124
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    complement(474..488)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(701..982)
                     /locus_tag="HEP86_RS05200"
                     /old_locus_tag="HEP86_05200"
     CDS             complement(701..982)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521399.1"
                     /locus_tag="HEP86_RS05200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05200"
                     /product="hypothetical protein"
                     /protein_id="WP_168477694.1"
                     /transl_table=11
                     /translation="MSSSSADRSRPPLRQAVTRLLPARSVIGFLALLVVLGMLSYAAGT
                     AVGPVAPGLHPAGGTRTGGSTPGDGGDMGGMHGMGAAAPGPVPVGAPR"
     gene            1239..2507
                     /locus_tag="HEP86_RS05205"
                     /old_locus_tag="HEP86_05205"
     CDS             1239..2507
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606588.1"
                     /locus_tag="HEP86_RS05205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05205"
                     /product="cytochrome P450"
                     /protein_id="WP_168477696.1"
                     /sec_met_domain="p450 (E-value: 1.2e-17, bitscore: 62.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPSSEPVELYGPEYKRDPYPLYAELRERGPVHRVRFPSGVCAWL
                     VTGYEAAHRALTDPRLGKHHSRGNAAWRARASIMPEPQHSQLQVHLLHQDPPRHTALRR
                     LITDAFAPQRVEALRPRFQAMADALLDGLPDSGAADLVEVFAARFPFQVLAEVIGLPTE
                     FADRFDRDWGKVVQPVGPEDPGRPAYEARLRGLQQYIADLVRHKRAESGEDLLSRLVAA
                     RDAGQLGQEELDSMVFQLLVAGQEPVTNQITTMLVTLLRHPAQLTTLAGRPELLPHAVE
                     ELLRHDSAFELTTWRFFAEDTELYGTRIPAGDSVIVSLSAANRDDRQFPDADALHFDRT
                     PNAHLAFGHGIHFCPGAALARIELQVALGTLLRRLPELRLAVQEDELSWTPAVLARGVD
                     RLPVTYGGCPYAGSGANGPDAAC"
     gene            2585..3472
                     /locus_tag="HEP86_RS05210"
                     /old_locus_tag="HEP86_05210"
     CDS             2585..3472
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DIT1_PvcA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979694.1"
                     /locus_tag="HEP86_RS05210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05210"
                     /product="isocyanide synthase family protein"
                     /protein_id="WP_248001572.1"
                     /sec_met_domain="DIT1_PvcA (E-value: 1.6e-75, bitscore:
                     252.9, seeds: 112, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAALLPYRRTLDTGHADTPDAFPAHLRQLAVPVAAGEPIVFTLP
                     GFPCKSPNPAKVLGHLPDEGERLALRFLDALCARIAAHHPPGARVVICSDGHVFSDLIQ
                     VPDRDIDAYADALRALIHDEGLTRLDVFDLRDVYGQRLSHDAKRSLVHERYAPDLETLR
                     SLTRTDEPTRRLYQGITRFLFEDSVAFAGTRSALQRSCRRRAYGVMQRSRAWGELIAAH
                     HPEAFRLSIHPQPRGSAKFGIRLLEAPDAWLTPWHSCVLEHADGRRELLHRAEAERLGR
                     LVYRQGRPSHFVAG"
     misc_feature    2756..2758
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3488..4276)
                     /locus_tag="HEP86_RS05215"
                     /old_locus_tag="HEP86_05215"
     CDS             complement(3488..4276)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606586.1"
                     /locus_tag="HEP86_RS05215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05215"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_168477698.1"
                     /transl_table=11
                     /translation="MNVEIEGLHVGYAGRDVVAGVQLMAAAGEIAGLVGPNGSGKSTVL
                     RTVYRHLRPTAGRVLLAGTDLRTLSPGRTARQVAALPQERGSDFELTVREVVTMGRTPY
                     KRAFAGDDRADRETVARALAAVGMAGQGARRFSTLSGGERQRALLARAFAQDPEVLVLD
                     EPTNHLDVRHQVELLALLRAQRRTTLISLHDLNAAASLCDRLHVLHAGRVVASGTPRAV
                     LTPQLLAEVFGVRAAVTEHPLTGDPLIAFDHREPLPADGG"
     gene            complement(4273..5331)
                     /locus_tag="HEP86_RS05220"
                     /old_locus_tag="HEP86_05220"
     CDS             complement(4273..5331)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720813.1"
                     /locus_tag="HEP86_RS05220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05220"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_248001573.1"
                     /transl_table=11
                     /translation="MGEEGAEQSGRWTPRAGLLALGLGVALVAALTAAVSLGATDIAPG
                     HVWSVVFRRLGGAPPRPGTDDLIVWQLRVPRALLAALVGAGLGLVGTATQALVRNPLAD
                     PYLLGISNGASLGAVTAIVLGVTAGGSLGLGLSGAAFAGALGSFALVWWMARRGGGFSP
                     LRLVLAGVGVGQFLSGFTSYLVLQAGDEQQTRSVLFWLMGSLSGATWQMLWLPALAVAA
                     GLLALQARARAMNALIMGDETAAGVGVDVTRLRRELFVVAGLLTGVLVAVSGAIGFVGL
                     MVPHLCRLLLGGDHRRLLPLSALTGSLLLVVVDLVCRTAMDTQELPIGVVTAMIGAPAL
                     LFILDRRLEEGR"
     gene            complement(5358..6431)
                     /locus_tag="HEP86_RS05225"
                     /old_locus_tag="HEP86_05225"
     CDS             complement(5358..6431)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606584.1"
                     /locus_tag="HEP86_RS05225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05225"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_168477702.1"
                     /transl_table=11
                     /translation="MRPWKLCGVAVVVAVAVTGCGGGAGGGPGADQGASGHGGAGFPVR
                     VADCQGVTTTFSAAPRKIVTSNAAALEMLLRLGAGDRVIGTGFPPGKGTLPGGLDAGAR
                     KVPVLSKSVIPKEKLLGSGADLYIDSFAAMKIMGKAGDAPTAEEFKAAGIKHLYLASTA
                     CAPMADKPQRDLSGVEGDIKRLGAVTGTAERADALVAGMRAKVGKVRRAVGDIPAGKRP
                     TYFFFDYDAGTKQPVAVCRKQVANAVIGQAGARNVFEGCDGDFKPVSWEDVVAKNPDWI
                     QLGVRNRGDAKANAKAFDEAAAFLKSFPATKGLAAVRNEKFLRIGSERTTVAGVGTADA
                     VEEIAHTIHPARFKAAR"
     gene            complement(6533..7462)
                     /locus_tag="HEP86_RS05230"
                     /old_locus_tag="HEP86_05230"
     CDS             complement(6533..7462)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020397757.1"
                     /locus_tag="HEP86_RS05230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05230"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_168483552.1"
                     /transl_table=11
                     /translation="MDLTAVRTVVAVADAGQFQDAATTLSITQQAVSKRIAALEKDLGV
                     RLFTRTARGARLTIDGQAFLPHARELIRAAERAAASVRPGSRALRVDVIGRRLCPAGLL
                     RDFHRAHPDTELDVVTLFDADSAIAAVRSGTIDASFRAVTLPARQLPDGVEAAWVFDEP
                     IQLLTGPAHPLATTRTVTPAQLAGHRIWMPGIVAGTEWAAYYEDLATEFGLTIEVTGPD
                     FGTEPLLDTIADSASLATFVGADTRLVWPADQDLRRVPVHDPTPVYPHSLIRRTDNPHP
                     ALTTLRSYLAATRPADRADGTWTPRWAR"
     gene            7602..8846
                     /locus_tag="HEP86_RS05235"
                     /old_locus_tag="HEP86_05235"
     CDS             7602..8846
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058442.1"
                     /locus_tag="HEP86_RS05235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05235"
                     /product="MFS transporter"
                     /protein_id="WP_168477704.1"
                     /transl_table=11
                     /translation="MQGGRSLGRQFGWLWAAYGVSAFGTRLAFDAFPLIAVLVLHTGPA
                     AVSLLAAAGLAVGAAVAVPLGPWVEFRRKRPVMIAMDLARCAALLTVPAAYALGLLGFV
                     QLLVVSVVVAAADITFNAAGGACLKALVRPADLLVANSRFESTNWTATVLGPPLGGAAI
                     GLFGPVLTVLADAVSYLLSAVGIRAIGGKEERPVRTGAPRLRAGDLLEGWRYLLTHPAL
                     RPLFFNTVLVNGLIMATSLLLAVLLLGRLGFAPWQYGLAFAVPCVGGLIGARLAQRLVA
                     RFGQHKVLYTAGTLRACWSLGLVLVRPGTAGLVLVMVVELGLITCMGVFNPVFATYRLD
                     RTAPDRITRTLSAWSVTSKTTTAALTGLWGLLAALTGPRTAIAAAGLLLLVTPLLLPRH
                     AHAPRHEPEVAASHL"
     misc_feature    complement(9051..9068)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(9079..9091)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            9227..9958
                     /locus_tag="HEP86_RS05240"
                     /old_locus_tag="HEP86_05240"
     CDS             9227..9958
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS05240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_05240"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_168477705.1"
                     /transl_table=11
                     /translation="MDASDLHPADGLRAVVAAIDELLRDLDLGRDVIDIDHLSHRTGLP
                     VPRVQALLDDTGEESEQVQDSFQDRLVFLRETRRKPDGKMYTLDEIGAGAGISHGQVGY
                     LLNGKRKSPGLDVTRKLEKFFEVEPGFFTATERQALYRALQSTHEQLTHLALLRGKGIN
                     RLAMRSGTSGDSRIDRELRDALSEVLSRPDGEDPEVRELTDRMRSLPSKSRRRVFPLIQ
                     GLLGLARPENEERPSPGRPGG"
     gene            complement(10001..10981)
                     /locus_tag="HEP86_RS05245"
                     /old_locus_tag="HEP86_05245"
     CDS             complement(10001..10981)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604592.1"
                     /locus_tag="HEP86_RS05245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05245"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_168477707.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-28, bitscore:
                     98.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.1e-13,
                     bitscore: 47.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATWPKTLDQAGITDPALRRDYSEQRQLVAHYARAEYTAVRLLLP
                     APLVPDVIAATAFMHHSDNLIDQGPAEERIAALADWESRVQAALKSGEADQPVLRTLLD
                     TLTRQPQLRQYVEDFLAGAPLEVKTAGFATEGDFQHYIDGYSLPAFLLIACLLGDGAPT
                     AAYVAGCRTFIEASQRLDFLNDLAEDLADGRLGIPEELLTRHGLTRDGLTGTGPTGKDG
                     AAVDGLRPLLADQVRQIRSGFSASYGLVDLVPARNRPFVRALVSIQGLTLRAAARKGTA
                     LLDGSARPPVAAALRILAREYAAARRGRDAKPAVRGSEPTAGKTA"
     misc_feature    10994..11011
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(11098..12381)
                     /locus_tag="HEP86_RS05250"
                     /old_locus_tag="HEP86_05250"
     CDS             complement(11098..12381)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="HEP86_RS05250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05250"
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_168477709.1"
                     /transl_table=11
                     /translation="MSESVSNVVYLIIAVIDFVIAGWKCLALLRDPTPTLSLITVNFVA
                     SGLVFAMAAPAGYRMLGDLTGVPSFATLPVYIGILSCFSLLHLLTMLWDPRLRQIPAVL
                     RRRVTVWSAVYLAAPAVMVVAFCSADLSGPMDPLKFNTNFAGDPLIQVFLAVFLATLAC
                     GTLNTYRRCRKLNPANPRFQRALRSFGTAMLFVFGYVVCSVPAIALAALGNHALDTVGV
                     LGSTFGSIGALITSYGLSGAAVGAWLRERRDIKALQPLWDLVVEGVDEDLAFSVDSARS
                     HRLAWNVGFNLHRRVIEILDGMRALRPWVSPLPAAAVHAAQEASRGTADARPLPEQELQ
                     AAATAAALRDAVQRLQAARLEAAAQGHSGQPQPPEGPQVALPGEDTPASDERQRLLRVA
                     QALTAPLVTTALQVVRVQRSAAEVSEGQ"
     gene            complement(12374..12991)
                     /locus_tag="HEP86_RS05255"
                     /old_locus_tag="HEP86_05255"
     CDS             complement(12374..12991)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS05255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_05255"
                     /product="hypothetical protein"
                     /protein_id="WP_168477711.1"
                     /transl_table=11
                     /translation="MWWPRRHGPARQAKAPQPTRHRPPSSPWTSLREQLAVFFATWSVT
                     RLVHRDLGLSGVRDMQGLVDAVAVRRNKPITITEVPLPQQVSGFCARGKDRDFIVVDAT
                     ANELTRLHVSLHELFHLWEEHPAEDGSAGQLMTEETVRQLLPGLKTGPVLKVLNRSHYD
                     SAHERRAEAFATVMLQRHLELRRDQRTNGFLSSALSHRRSGV"
     gene            13308..13955
                     /locus_tag="HEP86_RS05260"
                     /old_locus_tag="HEP86_05260"
     CDS             13308..13955
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014818415.1"
                     /locus_tag="HEP86_RS05260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05260"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_168477713.1"
                     /transl_table=11
                     /translation="MAQLLRVQNFTISSDGIGAGADQSLERPFGHVAPERLFAWAGATA
                     SWPMRTDPGGSRGLDDYFARDYTHHIGAEIMGRNKFGPQRGPWHDPEWRGWWGDEPPFH
                     TPVFVLTHHARPSFTLSDTTFHFVGGDPATVLEQAREAAQGKDVRLGGGVSTIRQFLDA
                     DLVDTLHVAVAPVTLGSGLRLWDSPDELLDRFHLEVVPSPSGSVTHHLFWRK"
     gene            complement(14012..14473)
                     /locus_tag="HEP86_RS05265"
                     /old_locus_tag="HEP86_05265"
     CDS             complement(14012..14473)
                     /GO_function="GO:0030551 - cyclic nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091744.1"
                     /locus_tag="HEP86_RS05265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05265"
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="WP_168477715.1"
                     /transl_table=11
                     /translation="MTMIENMLDELPPDRRRQLTDMAVEVSLPRATRLFEEGRRADRFW
                     IIRSGQVVLDQHVPGRRAAVVETLGRGELLGWSWMFPPFLWHLGAETVGPVDAVEFDAR
                     AIRELCETDPVLGRAMYRYVAKTVADRLHGTRTRLLDLYGPQGSGGLDP"
     misc_feature    complement(14448..14463)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.17"
                     /tool="antismash"
     misc_feature    14449..14462
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.83"
                     /tool="antismash"
     gene            complement(14573..17449)
                     /locus_tag="HEP86_RS05270"
                     /old_locus_tag="HEP86_05270"
     CDS             complement(14573..17449)
                     /GO_function="GO:0015440 - ABC-type peptide transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091743.1"
                     /locus_tag="HEP86_RS05270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05270"
                     /product="NHLP bacteriocin export ABC transporter
                     permease/ATPase subunit"
                     /protein_id="WP_168477717.1"
                     /transl_table=11
                     /translation="MSVPPSTVVGPGDTDAVTYALGGLGTPVDCTGLRSVPLEGPHVLW
                     LVTGGSLDLFAVDAAQEGHWHFLGRLEAGTLLLGPVAGPQHTLLGRPSQDCLLRRIPLR
                     ELPRYEYGEYDTGAFPQYGAQGYGNDPAYGGQGEAPSALEHAFALGTARSLGVLFEAPL
                     DGRPGDEAVADDDILWMPVPPGTVQYGASYNAEAAGDLLVDPELWQQMVNQQYRLLSAV
                     DRWIEQLERAHEDRTAAGIKAGETVRERADQALVASIGRAGRGSSTTDRTSDDTTFAVC
                     RTVAEAAGITLTEPPKGGAVNDRITPVERIAVSSRIRTRAVRLQGPWWRTNTGPLVGHR
                     AKSGAPVALLWRRGRYEAVNPVSGLRMRLGKDNADELEPRAVMFYRPLPERPMSLWRLM
                     LFSLRGTRMDVRNLALSGLVTVGLGSLVPIATGKVLGEYVPSADKSLIVQASLAIMITS
                     VVSAAFMLLQNLTVLRMEGRIESTLQPAVWDRLLRLPTKFFTERSTGELASAAMGISAI
                     RRVLSGLGPVAVQSTTIGAMNLVLLLVYSVPLALAAVAMLIVIGAVFLAMGLWELRWQR
                     RLVKLGNKLNNQAFQTLRGLPKLRVAAAESFAYAAWAREFARSRELQQKAGRIKNLTTV
                     LNAVYLPVCSLTLFMLLAGPARGTMSAASFLTFNTSVTMLLTAVTQITGAFISAAAAMP
                     MFEQIKPVLDEKPEVRGASAQPGTLSGGIEAKKLSFRYTDDGPLVLDDVSLRVQPGEFV
                     AVVGPSGCGKSTLLRLLIGFDKPSSGSVLYDGQDLAALDQAAVRRQCGVVLQNAQPLTG
                     SILDCICGAEAFTQEEAWAAAEMAGLAEDIKRMPMGLHTMISGGGAISGGQRQRLMIAQ
                     ALVRRPRILFFDEATSALDNETQRIVSDSTRKLSASRLVIAHRLSTVMDADRVIVMAEG
                     RIVEQGAPAELLADTGGRLHDLVRRQLT"
     cand_cluster    15718..25945
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    15718..25945
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[20717:20945](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(20718..20945)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            complement(17451..19736)
                     /locus_tag="HEP86_RS05275"
                     /old_locus_tag="HEP86_05275"
     CDS             complement(17451..19736)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091742.1"
                     /locus_tag="HEP86_RS05275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05275"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_168477719.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.2e-38, bitscore:
                     127.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPHDSAAPQQQLPPPVRGRRRAEPAPGARRTRRAAPAPKPKKT
                     KTVRTPTVLQMEAVECGAASLAMVLAHYGRHVPLEELRIACGVSRDGSRASNLLKAARS
                     YGLQAKGMQMEPAALAEVQAPAILFWEFNHYVVYDGTGRRMGRRGVHINDPDKGRRFVA
                     TEDFDTSFTGVALVLEPGESFRKGGRKPGVLGAVPARMRGTTGTLLAALLASLLLVAVG
                     AAVPALSRTYIDMFLIGNQTSLLGPLFASMAAMVALTAVLTGLQQANLLRGRIISSTLT
                     SARFLRHLLRLPVTFFAQRSPADLVQRLQSNDAVAETLARDLAAAGVDGIVVILYAFLL
                     WTYDPQLTVIGVGIALLNVVAMRIVIRLRATHTQKLRADSARLTNTSYTGLQLIETMKA
                     TGGENGYFRRWAGQHATTLEEQQRLGVPSAALAVVAPTLATLNSALILWIGGLRAVEGH
                     ISIGLLVAFQALVTRFTAPITRLNGVAGRIQDFAADVARLKDVESFPVDTLYSRPEPEA
                     DNRRLKGHVTLEDITFGYSPLDKPLLTGFSLAVGPGRQVALVGGSGSGKSTVSRLISGL
                     YSPWEGTIRIDGQRLEDLSRSALAASVSFVDQDIFLFEGTVRDNVALWDPSIPDDAVIA
                     ALQDAALYDEVIAPRPDGIHSRVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSA
                     LDARTEQIIMDNLRRRGCACVIIAHRLSTVRDSDEIVVLDHGVVVERGRHEDLVAAGGP
                     YAELVKEH"
     gene            complement(19733..20539)
                     /locus_tag="HEP86_RS05280"
                     /old_locus_tag="HEP86_05280"
     CDS             complement(19733..20539)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="HEP86_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05280"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_168477721.1"
                     /transl_table=11
                     /translation="MQFRQQALSKLQSPEEIDLPVRFARPQGWLALTVTVLFVIAGSVW
                     AVTGTVSSTLNAPGILTHGQGSYVLQSPVAGQVTAVLAEEGKRVAAHTPVLRVRTAQGT
                     TVVRTLAAGRLTTMVATIGSVVTTGADVASVERIARTDDPLMATLYVPAGSGATVPVGA
                     SVDLTVQSVPTQQYGVLRGRVKAVGRTAQSRQRISTFLGSSQLGEEFSQHGQPVAVLVQ
                     LDAVPHSKSGYAWSTSDGPPYAVDSMTPASGAVHLAAQHPIDWLLP"
     misc_feature    20504..20516
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    20664..20676
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(20718..20945)
                     /locus_tag="HEP86_RS05285"
                     /old_locus_tag="HEP86_05285"
     CDS             complement(20718..20945)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="HEP86_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05285"
                     /product="type A2 lantipeptide"
                     /protein_id="WP_168477723.1"
                     /sec_met_domain="strepbact (E-value: 2.8e-30, bitscore:
                     103.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVQTQEISDSDLDNVSGGLVGGVVGTATNTVDSIAPVSGA
                     VGTATGLVDGVAGTDTAGVVGTATGLVAGL"
     gene            21082..21267
                     /locus_tag="HEP86_RS05290"
                     /old_locus_tag="HEP86_05290"
     CDS             21082..21267
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_05290"
                     /product="hypothetical protein"
                     /protein_id="WP_168477725.1"
                     /transl_table=11
                     /translation="MQARCAANRVAADPGDITLSKYLTCTPVHDLVAASSHLLRFLFRG
                     LGKRPFGELDIPSPNR"
     misc_feature    complement(21289..21299)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(21491..21511)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.03"
                     /tool="antismash"
     gene            21713..22744
                     /locus_tag="HEP86_RS05295"
                     /old_locus_tag="HEP86_05295"
     CDS             21713..22744
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091739.1"
                     /locus_tag="HEP86_RS05295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05295"
                     /product="PHP domain-containing protein"
                     /protein_id="WP_168477727.1"
                     /transl_table=11
                     /translation="MEPVEALERIAFLLERQGAVTYRVQAFRTAATVIGALSADELRTR
                     ARSGSLARLKGLGPKTTRVIEEALTGARPEYLTHLEEEAGGPLVEGDQGQRLRQALRGD
                     CHLHSDWSDGGSPVETMARAARDLGHTWCVLTDHSPRLTVARGLTAERLRQQLTLVAEV
                     NERLAPFRLLTGIECDILDDGSLDQEPELLEQLDVVVASVHSKLRMDKRPMTRRLLAAV
                     RNPLVDVLGHCTGRQITGKLRPESQFDAGEVFAACAEHHTAVEINCRPDRFDPPRRLLR
                     LALETGTLFSIDSDAHAPGQLDWQIYGCARAEECGVPPERVINTWTERQLATWTRTGRT
                     PHR"
     gene            22785..23453
                     /locus_tag="HEP86_RS05300"
                     /old_locus_tag="HEP86_05300"
     CDS             22785..23453
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1226: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091738.1"
                     /locus_tag="HEP86_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05300"
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="WP_168477729.1"
                     /transl_table=11
                     /translation="MDTRTEHEMVAVPPGRVTLSDRRTRRSWPVELTPYRLAPCPVTQE
                     RYAQVTGERPSSARGDRLPVEGVSWWDAVRFCNALSAQEGLAPAYRLDTDTERIEWDTA
                     ADGYRLPTEAEWEHACRAGTTAARYGRLDDIAWHRGNSHERIHEVGGRQPNAWGLSDML
                     GNVWEWCWDVYDAEVYGSYRVLRGGGWFDERWSCRASVRRRSHPTFRIDDVGFRIARSL
                     "
     gene            complement(23477..24835)
                     /locus_tag="HEP86_RS05305"
                     /old_locus_tag="HEP86_05305"
     CDS             complement(23477..24835)
                     /GO_function="GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA]"
                     /GO_process="GO:0006821 - chloride transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091737.1"
                     /locus_tag="HEP86_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05305"
                     /product="chloride channel protein"
                     /protein_id="WP_168477731.1"
                     /transl_table=11
                     /translation="MSVGPAGPVGGTPTTAPQDPYALVRTRGYLKLLLVAGAIGFPVCA
                     VAFGFLALVHELEPLIYHDLPRALGFTGTPIWWPVPMLLIAGLLVGLTVRYLPGGGGHE
                     PADGLALKGAPPLSALPGVFLAALTSLSFGVVLGPEAPLIALGGGLAAGAVRLLNRNMP
                     AQAAAAVGAAGSFAAISALLGSPLLGAFLLMEVSGLGGPMLGIVLVPGLLASGLGALIF
                     TGLGDWTGLGTYSLALHDIPRAAGPTIPEFGWALVIGLAAGFAASGVRRLALYLKGHVV
                     RHRVPATVVMGLVVGVLAMAFAAATGKPASEMLYSGQSALGSLFRDSAGYTVGALLLLI
                     LCKGLAYCASLSAFRGGPIFPALFLGAAGGVVLSHLPGLSLTAGFAMGVGAMCVAMLRL
                     PMTSVLLATLLLGKSGLTVMPLVIVAVVVAYVVALRLTPATAPDLPSTAPHPA"
     misc_feature    complement(24890..24905)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     gene            complement(24994..25902)
                     /locus_tag="HEP86_RS05310"
                     /old_locus_tag="HEP86_05310"
     CDS             complement(24994..25902)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091736.1"
                     /locus_tag="HEP86_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05310"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_042152478.1"
                     /transl_table=11
                     /translation="MIEARRLHILRAVADHRTVTAAAAALYLTPSAVSQQLAALEQETG
                     HRLVERSARGVRLTAAGDILLTHANAVLAQLERAESELAAYGSGEAGTVTVAAFATGIG
                     LVVAPALTALARTAPGIRVHVQDAEGDASLLMVLDRQVDVAVAVEYRGAPGADDPRLTR
                     VPLYAEPFDAVLPPGHRLADTDRLAVADLAGDPWIGPYPGNPCHDVVVLACEYAGFQPR
                     LEHTSDDFRAVVALASAAAGVALVPRSALRDMDLTGVVVRPVDDVAPTRRVFAAVRRGA
                     EEHPLFRPVLAALREAAASQG"
     misc_feature    complement(25867..25883)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
ORIGIN
        1 gccgtgccgt cgcccgcggt gggcagcagg ctgaacggca tcgtcatccc cggcgcaccg
       61 gccccgccga ggaacagcgc ataggtggac cagaggaagg aggcggcgac gccgagggag
      121 accagggtgt ccatggtcgc cgcgccgtgc cgcagcccgc gcagcgcacg ggtgtggaag
      181 ggggcggcgc cccagaccgc gacgggggcg gcaagcacga agcacagcca ctgccagttg
      241 cggaactgcc agcccggcac catcgacagg accaggacgg ggagcgaaag cagggcgacc
      301 gccagcagcc ggtgccgctc ggcgcgggcg ccgtcgtccg gagggtcctg gggggcggcg
      361 gtttccggtg cgtcgccggg gtcctggccg tcctgatggc cggtgggcgg cagcccgttc
      421 tccggggccg actcgggggc gggtgcacgg agctgtgcgg tgaacccggc cgcctcgacg
      481 gtgctgatga ggtcgtcgac ggagaccgcc gcggggtggc tgaccgtggc ccggccggtg
      541 gcgagattca ccgaggcggc gacgccgtcc agccggccga gcttcttctc gacccggccc
      601 acacaggcgg cacaggtcat cccgccgatg gtgagggtgg tgctgcgggc cggggtgggg
      661 gcgaggtccg gcgacggggt aacgggaccg ggctccggcg tcatcggggt gctcccaccg
      721 gcaccgggcc gggggccgcg gcacccatcc cgtgcatgcc gcccatgtcc ccgccatcgc
      781 cgggcgtgga ccctcccgta cgggtgccgc ccgccgggtg cagccccggg gcaaccggcc
      841 cgacggcggt cccggccgcg tacgacagca tgccgagcac caccagcagc gcgaggaaac
      901 cgatgaccga ccgggcgggc agcagccgtg tgacggcctg gcgaagaggg ggccgactgc
      961 ggtcggccga agagctggac atcgcgtcat cgtggcagct gacggtgggg cccggcggcc
     1021 gatccggggg ttgtgcgcac gtgaggtttg tcctgttccg ccgccggaac tcaccggccg
     1081 ccgcgcccga ctacctgggt ttggacggtg tccccacgcc cctcttcgcc cgccccggcc
     1141 gaaatcacct cccccggcgg gaactcggcg ctcccgttgc ccgacctctc caacgccgcg
     1201 ccaaccgggc gccggacccc caccgttgag gagccaccgt gtccccatcg tccgaacccg
     1261 tcgagctgta cggaccggag tacaaacgcg acccctatcc cctgtacgcc gagctgcgcg
     1321 agcgcggccc ggtccaccgg gtgcgctttc ccagcggggt gtgcgcctgg ctcgtcaccg
     1381 gctacgaagc cgcgcaccgg gccctcaccg acccccggct gggcaagcac cactcgcggg
     1441 gcaacgcggc ctggcgggcc cgcgcctcga tcatgcccga gccccagcac tcccagctcc
     1501 aggtgcatct gctccaccag gacccgccgc ggcacaccgc gctgcgccgg ctgatcaccg
     1561 atgccttcgc cccgcagcgg gtcgaggcgc tgcgcccgcg cttccaggcg atggccgacg
     1621 ccctgctcga cgggctgccg gacagcggcg ccgccgacct ggtcgaggtc ttcgccgccc
     1681 gcttcccctt ccaggtgctc gccgaagtca tcgggctgcc gacggagttc gcggaccgct
     1741 tcgaccggga ctggggcaag gtcgtccagc ccgtggggcc cgaggacccg ggccgcccgg
     1801 cgtacgaggc gcggctgcgc gggcttcagc agtacatcgc cgatctggtc cgccacaagc
     1861 gcgccgagag cggcgaggat ctgctctccc ggctggtggc cgcccgcgat gcgggccaac
     1921 tcggccagga ggagctcgat tcgatggtct tccaactact ggtggcgggc caggaaccgg
     1981 tcacgaacca gatcaccacg atgctggtca ccctgctgcg ccaccccgcg cagctcacga
     2041 cgctggcggg ccgccccgaa ctgctgccgc acgccgtcga ggaacttctg cgtcatgaca
     2101 gcgccttcga gctgacgacc tggcggttct tcgccgagga caccgagctg tacggcaccc
     2161 ggatcccggc gggcgactcc gtcatcgtgt cgctgagcgc ggccaaccgc gacgaccggc
     2221 agttccccga tgcggacgcc ctgcacttcg accgcacccc caatgcgcat ctcgccttcg
     2281 gccacggcat ccacttctgc cccggcgccg cgctcgcccg tatcgaactc caggtcgccc
     2341 tgggcacctt gctgagacgg ctgccggagc tgcggctcgc cgtccaggag gacgagctgt
     2401 catggacccc ggcagtactg gcgcgcggcg tcgaccggtt gccggtgacc tacggcggct
     2461 gcccgtacgc gggctccggt gcgaacgggc ccgatgccgc gtgctgacca gcccgccgcc
     2521 gctgacccac ccggcgcccc cgctcccgga ggcgccctcc gacgtccggg cccgctgcgc
     2581 cgaggtgctc gccgcgctcc tgccctaccg gcgcaccctg gacaccggcc acgcggacac
     2641 ccccgacgcc ttccccgccc acctgcggca gctcgccgtc ccggtggccg cgggtgagcc
     2701 gatcgtcttc accctgccgg gcttcccctg caagtccccc aacccggcca aggtgttagg
     2761 gcacctcccc gacgagggcg aacggctggc cctgcgcttc ctggacgcgc tctgcgcccg
     2821 gatcgcggcg caccacccgc ccggggcgcg ggtggtcatc tgctcggacg ggcatgtctt
     2881 cagcgatctc atccaggtgc cggaccgcga catcgacgcc tatgccgacg cgctgcgcgc
     2941 actgatccac gacgagggtc tgacccggct cgatgtcttc gatctgcggg atgtctacgg
     3001 gcagcggctg tcccacgacg ccaagcggtc cctggtccat gagcgctacg cgcctgacct
     3061 ggagaccctg cggtccctga cccgcaccga cgagccgacc cggcggctgt accagggcat
     3121 cacccggttc ctcttcgagg actccgtcgc tttcgcgggg acccgttcgg cacttcagcg
     3181 cagctgccgg cggcgcgcgt acggggtgat gcagcgcagc cgcgcctggg gcgagctgat
     3241 cgccgcccac catccggagg cgttccggct ctccatccat ccgcagccgc gcggctccgc
     3301 caagttcggc atccggctgc tcgaagcgcc cgacgcgtgg ctgacgccct ggcactcgtg
     3361 cgtgctcgaa catgccgacg ggcggcggga gttgctgcac cgggcggaag ccgagcggct
     3421 cggccggctg gtgtatcgcc agggacggcc gagccacttc gtggccgggt gaggggcggg
     3481 gtgggcgtca gccgccgtcg gcgggcagcg gctcccggtg gtcgaaggcg atcagcggat
     3541 ccccggtgag cggatgctcg gtcaccgcgg cgcgcacccc gaagacctcg gccagcagct
     3601 gcggcgtcag caccgcacgg ggcgttccgg aggccaccac ccgtccggcg tgcagcacat
     3661 gcagccggtc gcacagggac gccgccgcgt tcagatcgtg cagcgagatg agcgtggtac
     3721 ggcgctgggc gcgcagcagc gcgagcagct ccacctgatg gcgtacatcg aggtgattgg
     3781 tgggctcgtc cagcactagc acctccgggt cctgggcgaa cgcccgtgcc aggagcgccc
     3841 gttgacgttc cccgcccgac agggtggaga agcggcgggc gccctgtccg gccatgccga
     3901 cggcggccag cgcgcgggcc acggtctccc ggtcggcccg gtcgtcgccc gcgaaggccc
     3961 gcttgtaggg cgtacggccc atggtcacca cttcgcggac ggtcagctcg aagtcgctgc
     4021 cgcgctcctg gggcagcgcg gcgacctgcc gggcggtccg gcccggggag agcgtgcgga
     4081 ggtcggtccc ggcgagcagt acccgtccgg cggtgggccg cagatgccgg tagacggtgc
     4141 gcagcacggt ggacttgccg ctgccgttgg gcccgaccag tccggcgatc tcaccggccg
     4201 ccgccatcag ctgcaccccg gcgacgacat cccgtcccgc gtagccgacg tgcagcccct
     4261 cgatctcgac gttcatcgcc cctcctccag ccgccggtcc aggatgaaca gcagggcggg
     4321 cgccccgatc atcgcggtga ccacaccgat cggcagttcc tgggtgtcca tggccgtacg
     4381 gcatacgagg tccaccacca ccagcagcag cgaaccggtc agcgcggaca acggcagcag
     4441 ccggcggtgg tcgccgccga ggagcagccg gcacagatgc ggcaccatca ggcccacgaa
     4501 gccgatggca ccggagaccg cgaccaggac gccggtcagc agtccggcca ccacgaacag
     4561 ctcgcggcgc agccgggtga cgtccacgcc caccccggcc gcggtctcat cgcccatgat
     4621 cagcgcgttc atggcacggg cccgcgcctg aagggccagc agcccggcgg cgaccgcgag
     4681 ggccggcagc cacagcatct gccaggtggc cccgctcagg ctgcccatca gccagaacag
     4741 cacgctgcgg gtctgctgtt catccccggc ctgtaggacg aggtagctgg tgaagccgga
     4801 caggaactgc ccgacgccca caccggccag caccagccgc agcggggaga atcccccgcc
     4861 gcgccgggcc atccaccaca ccagcgcgaa cgagccgagc gccccggcga acgcggcccc
     4921 cgagagcccc agccccaggc tcccgccggc cgtgacgccc agcacgatgg cggtgaccgc
     4981 gcccagcgac gcgccgttgg agatccccag cagatacggg tccgccagcg ggttgcgtac
     5041 cagcgcctgg gtcgcggtcc ccaccaggcc gagtcccgcc cccaccagcg ccgccaacag
     5101 ggcgcgcggt acgcgcagtt gccacacgat caggtcgtcg gtcccgggcc ggggcggcgc
     5161 gccgccgagc cgccggaaca ccaccgacca gacatgtccg ggcgcgatat cggtggcgcc
     5221 cagcgagacc gccgcggtca gggccgccac cagcgcgacc ccgagcccca gggcgagcag
     5281 cccggcacgc ggcgtccacc gcccggactg ctcggcccct tcctcaccta tgtgcggatc
     5341 gatgaccgtc gcggccacta ccgcgccgcc ttgaagcgcg cggggtggat ggtgtgcgcg
     5401 atctcctcga cggcgtccgc ggtgccgacc ccggcgaccg tcgtccgctc cgagccgatc
     5461 cgcagaaact tctcgttgcg caccgccgcg agccccttgg tggcggggaa gctcttcagg
     5521 aacgccgcgg cctcgtcgaa cgccttggcg ttggccttcg cgtcgccccg gttgcggacc
     5581 ccgagctgga tccagtccgg gttcttggcg accacgtcct cccaggacac cggcttgaag
     5641 tcgccgtcac agccctcgaa gacattgcgc gccccggcct ggccgatcac cgcgttggcc
     5701 acctgcttgc ggcagaccgc gaccggctgc ttggtaccgg cgtcgtagtc gaagaagaag
     5761 tacgtcggcc gcttgccggc cgggatgtcg cccaccgccc ggcgtacctt gccgaccttc
     5821 gcccgcatcc ccgcgacgag ggcgtccgcc cgctcggcgg tgccggtcac cgcgcccagc
     5881 cgcttgatgt ccccctccac accggacaga tcgcgctgcg gcttgtcggc catcggcgca
     5941 cacgcggtgg acgccaggta gaggtgcttg atgcccgccg ccttgaactc ctccgcggtc
     6001 ggcgcgtccc ccgccttgcc catgatcttc atcgccgcga aggagtcgat atacagatcg
     6061 gcacccgaac cgagcagctt ctccttgggg atcacggact tcgacagcac cggcaccttc
     6121 ctggccccgg catccagccc accgggcaac gtgcccttgc cgggcgggaa tccggtcccg
     6181 atgacccggt caccggcgcc cagccgcagc agcatctcca gcgcggcggc attgctcgtg
     6241 acgatcttgc gcggcgcggc ggagaacgtg gtcgtgaccc cctggcagtc ggcgacccgt
     6301 acgggaaaac ccgccccacc gtgccccgac gccccctggt ccgcgcccgg cccgcccccc
     6361 gctccgccgc cgcacccggt gacggccacc gcgacaacta ccgcgacacc gcacaacttc
     6421 caaggacgca tcgtgcttct cccctatccc tcaccagccg gcaccccggc cgcatcaccg
     6481 accgcccacc ctcaccggcg tcggccaggc ggtgtccagc ccccgccatc cctcaccgcg
     6541 cccagcgcgg tgtccatgtc ccgtccgcgc ggtcggcggg ccgtgtggcg gcgaggtagc
     6601 tgcgcagggt ggtgagggcg gggtgggggt tgtcggtgcg ccggatcagg gagtgggggt
     6661 agaccggtgt cgggtcgtgt acggggacgc ggcgcaagtc ctggtcggcg ggccagacga
     6721 ggcgggtgtc ggcgccgacg aaggtggcca gtgaggcgga gtcggcgatc gtgtcgagga
     6781 gtggttcggt gccgaagtcg gggccggtca cctcgatggt gaggccgaac tcggtggcga
     6841 ggtcctcgta gtaggcggcc cattccgtac cggcgacgat gccgggcatc cagatccggt
     6901 gtccggcgag ctgcgcgggg gtgaccgtgc gggtggtggc caacggatgg gccggtccgg
     6961 tgagcagctg gatgggctcg tcgaagaccc aggcggcctc gacgccgtcg gggagttggc
     7021 gggcgggcag ggtgaccgcg cggaaggacg cgtcgatggt gcccgagcgg accgcggcga
     7081 tggccgagtc ggcgtcgaag agcgtcacca cgtcgagttc ggtgtcgggg tgcgcgcggt
     7141 ggaagtcgcg cagcagaccc gccgggcaga gccgccggcc gatcacatcg acgcgcagcg
     7201 cgcggctgcc gggccggacc gaggcggctg cccgctccgc ggcccggatc agctcgcggg
     7261 cgtggggcag gaacgcctgc ccgtcgatgg tgagccgggc gccgcgcgca gtgcgggtga
     7321 acagccgcac accgaggtcc ttctccagcg cggcgatgcg cttggagacg gcctgctggg
     7381 tgatcgagag ggtggtggcg gcgtcctgga attgccccgc gtcggcgacg gcgacgacgg
     7441 tgcgtacggc ggtgagatcc acgcccggca gtgtagtcac acaacggatg gttgtggcct
     7501 gccgggtgga ttggttgttt gatcgggggc ttgctgctgg cttggatgga cccggtcaac
     7561 gtggagttgt cgggggcggg gcatcgaggg gcgtggtggg catgcagggc ggacggtcgc
     7621 tggggcggca gttcgggtgg ctgtgggcgg cgtacggggt cagtgcgttc gggacccggc
     7681 tcgcgttcga cgcgtttccg ttgatcgcgg ttctggtgct gcacaccggg ccggcggcgg
     7741 tgtcactgct ggccgccgcg gggctggcgg tgggggcggc ggtggcggtg ccgctcggcc
     7801 cgtgggtgga gttccgccgc aaacggcccg tgatgatcgc gatggatctg gcgcggtgcg
     7861 cggcgctgct gaccgtcccc gccgcgtacg ccctcggtct gctcggcttc gtccagctcc
     7921 tggtcgtatc ggtcgtcgtc gccgcggcgg acatcacctt caacgcggcc ggcggcgcct
     7981 gtttgaaggc gctggtgcgg ccggcggacc tgctcgtcgc gaactcccgg ttcgagtcca
     8041 cgaactggac cgccaccgtg ctcggcccgc cgctcggcgg ggccgcgatc gggctgttcg
     8101 gtccggtgct gaccgtgctg gccgatgcgg tcagctatct gctctcggcg gtgggaatcc
     8161 gcgcgatcgg gggcaaggag gagcggcccg tacgcaccgg tgcaccacgg ctccgggccg
     8221 gggacctgct cgaagggtgg cggtacctgc tgacccaccc ggcgctgcgt ccgctgttct
     8281 tcaacacggt tctggtcaac ggcctgatca tggcgacgtc actgctgctg gccgtccttc
     8341 tgctcgggcg gctcgggttc gccccctggc agtacggtct cgccttcgcg gtgccctgcg
     8401 tcggcgggct gatcggcgca cgactggccc agcggctcgt cgcgcggttc ggacagcaca
     8461 aggtcctgta cacggcgggg acgctacggg cgtgttggtc gctcgggctg gtcctcgtcc
     8521 gccccggcac cgccgggctg gtgctcgtca tggtcgtcga gctggggctc atcacctgca
     8581 tgggcgtctt caacccggtg ttcgcgacct accggctcga ccggacggcg ccggaccgga
     8641 tcacccgcac cctgtccgcg tggtcggtca ccagcaagac caccaccgcg gccctgaccg
     8701 ggctatgggg cctgctggcc gccctcaccg gcccccgcac cgcgatcgcg gccgccggtc
     8761 tcctcctgct cgtgaccccg ctcctgctcc cccggcacgc gcacgcgccg cgacacgagc
     8821 cggaagtggc cgcgagtcac ctctgaaacg gcccggtcgc cctctggggc gtcatctgcg
     8881 gccaacaggc ggtgtggtgc cgggctctcc cctgtggagc ccggcaccac cgccgggaag
     8941 ggcggcagtt gcgaggtgcg gaaaatctgt gagcggcccc ctgcgcaaca tgcccgccgg
     9001 tcgttcagcg gcatcgcctt ggtgaggatc cttcaaccaa acccacgttg tcaacaatcg
     9061 tttaacccaa gagtgctggt gacgacttca cgggccatcg gaatttgctc cttgacacaa
     9121 ttgtggtgcc attcatggcg tacggtgctg gctaccgtta acctcgaagc ggctgcgagc
     9181 atgccgccgt cccgtctgtc caccgaccag gagaccgccc atcgccatgg atgcctcaga
     9241 cttgcacccg gcggatggtc ttcgagccgt cgtcgcagcg atcgacgagc ttctccggga
     9301 tctggacctc gggcgcgacg tcatcgacat cgatcacctc tcgcaccgga ccggcctccc
     9361 ggtcccccgc gtacaggcgt tgctcgatga caccggcgag gaatccgagc aggtgcagga
     9421 ctccttccag gaccgcctcg tcttcctgcg ggagacccgc cgcaagcccg acgggaagat
     9481 gtacaccctt gacgaaatcg gtgccggagc cggtatctcc cacggccagg tcggctatct
     9541 cctgaacggg aagcggaaga gccccgggct ggatgtcacc cggaaactgg agaagttctt
     9601 cgaggtcgag ccgggcttct tcaccgccac cgaacgtcag gcgctgtacc gggcactcca
     9661 gtcgacgcat gagcagctga cccatctcgc gctgctcagg gggaagggca tcaaccggct
     9721 ggcgatgcgc agcggcacca gcggcgacag ccggatcgac cgggaactcc gggacgcgct
     9781 gtccgaggtc ctgagccggc ccgacggcga ggatcccgag gtacgggagc tcacggaccg
     9841 gatgcgctcg ctgccctcca agagcagaag gcgcgtcttt cccctgatcc aggggctgtt
     9901 gggcctggcc cggcccgaga acgaggagcg tccgtccccc ggccggcccg gcggctgaag
     9961 gggaccggac gccgctggtc cgcccggtcc gcctccagga tcaggccgtc ttgcctgccg
    10021 tcggctcgct acccctgacg gccggcttcg cgtcacggcc acgacgggcc gccgcgtact
    10081 cccgggcgag aatccgcagg gccgccgcca ccggcggccg ggcggaaccg tcgagcagcg
    10141 cggtcccctt ccgtgccgcg gcgcgcagcg tgaggccctg gatgctgacg agagcgcgga
    10201 cgaacggccg gttgcgggcg ggcaccagat ccaccagccc gtacgacgcc gaaaagcccg
    10261 agcggatctg ccggacctgg tcagcgagca gcgggcgcaa cccgtcaact gcggcgccgt
    10321 ccttgccggt cgggccggta ccggtcagtc cgtcgcgggt caggccgtgg cgggtgagga
    10381 gctcttcggg gatgccgagg cgtccgtcgg ccaggtcttc ggcgaggtcg ttgaggaagt
    10441 ccagccgctg gctcgcctcg atgaaggtcc ggcagccggc gacgtacgcg gcggtgggcg
    10501 ctccgtcgcc cagcaggcag gcgatgagca ggaaggcggg cagcgaatag ccgtcgatgt
    10561 agtgctggaa gtcgccttcc gtggcgaacc ccgccgtctt cacctccagt ggcgccccgg
    10621 cgaggaagtc ctcgacgtac tgccggagtt gcggctgcct ggtgagggtg tcgaggagcg
    10681 tccgcagcac gggctggtcg gcctcgccgc tcttgagggc ggcctgcacc cggctctccc
    10741 agtcggcgag cgcggcgatg cgctcctcgg ccggtccctg gtcgatgagg ttgtcgctgt
    10801 ggtgcatgaa cgcggtcgcg gcgatgacgt cgggcaccag cggcgcggga aggagcaggc
    10861 gcacggcggt gtactcggcg cgggcgtagt gcgccaccag ctgacgctgt tcgctgtagt
    10921 cacgacgcag cgcgggatcg gtgatccctg cctggtcgag cgtcttcggc catgtggcca
    10981 tcgtcagcgc ccctttcctc gagtgcggat tcaccttagg tgatcgcggc cgaggggacc
    11041 gatccgtccc ggcacgccca ggccggtacg ggagcgggcc agttccgccg tagcggacta
    11101 ctgcccttcg gacacctcgg cggcggaccg ctgtacgcgc acgacctgga gcgccgtggt
    11161 gaccagcggg gcggtgagcg cctgggcgac gcgcagcagc cgctggcgtt cgtcggaggc
    11221 cggggtgtcc tcgccgggca gcgccacctg cggcccctca ggcggctgcg gttggccgga
    11281 atgcccctgt gccgccgcct ccagccgggc ggcctggagg cgctgtaccg cgtcccgcag
    11341 ggcggcggcg gtggccgccg cctggagctc ctgctccggg agcggccggg cgtcggcggt
    11401 gccccgggac gcctcctgcg cggcgtggac ggcggccgcg ggcaggggcg acacccaggg
    11461 acgcaacgcg cgcatcccgt cgaggatctc gatcacccgg cggtgcaggt tgaaccccac
    11521 gttccatgcc aggcgatgac tccgtgcgct gtccacgctg aaggcgaggt cctcgtcgac
    11581 cccttcgacg acgaggtccc acaacggctg gagggccttg atgtcccggc gttcgcgcag
    11641 ccacgcgccc accgcggcgc cggagaggcc gtagctggtg atcagggcgc cgatcgagcc
    11701 gaaggtggag ccgagcaccc ccacggtgtc cagggcgtgg ttgccgaggg cggccagcgc
    11761 gatggccggg acggagcaga ccacatagcc gaagacgaac agcatggcgg tgccgaacga
    11821 gcgcagcgcg cgctggaacc gggggttcgc cgggttcagc ttgcggcacc gccggtaggt
    11881 gttgagggtt ccgcaggcca aggtggcgag gaagaccgcc aggaagacct ggatcagcgg
    11941 gtcacccgcg aagttggtgt tgaacttgag cgggtccatc ggcccggaca gatcggcgga
    12001 gcagaacgcg acgaccatga cggccggtgc cgcgagatac accgccgacc acaccgtgac
    12061 ccgacggcgc agcaccgccg ggatctgccg caatcgggga tcccacagca tcgtgagcag
    12121 gtggaggagg gagaagcagc tcaggatgcc gatgtagacg gggagggtgg cgaagctggg
    12181 gacgccggtg aggtccccca gcatccggta gcccgcgggt gcggccatcg cgaacaccag
    12241 gccggacgcc acgaagttca ccgtgatcaa ggacagcgtc ggggtgggat cgcgcagcag
    12301 cgccaggcac ttccacccgg cgatcacgaa gtcgatgacc gcgatgatca ggtagacgac
    12361 gttcgagaca ctctcagaca ccggacctcc tatgagagag cgccgaggag aggaacccgt
    12421 tggtgcgctg atcgcgccgc agttccaggt ggcgctggag catcacggtg gcgaaggcct
    12481 ctgcccgccg ctcatgagcg ctgtcgtagt gcgagcggtt gaggaccttc agcaccgggc
    12541 ccgtcttgag tccgggaagg agctgccgca cggtctcctc ggtcatgagc tggccggcgg
    12601 agccgtcctc ggccgggtgc tcctcccaca ggtggaacag ctcgtgcagg ctgacgtgca
    12661 ggcgggtcag ttcgttcgcg gtggcatcca ccacgatgaa gtcacggtcc ttgccccggg
    12721 cgcagaaccc ggacacctgc tgcggaagcg gcacttcggt gatcgtgatc ggcttgttgc
    12781 gccggacggc caccgcgtcg accagtccct gcatgtcccg tacgccggac agcccgaggt
    12841 cgcggtggac gagccgggtg acggaccagg tcgcgaagaa gaccgccaac tgctcccgga
    12901 gcgaggtcca cggggagctg ggcggccggt ggcgggtggg ctgcggcgct ttcgcctgcc
    12961 gcgcgggacc atgacgacgg ggccaccaca tgaacggata ctcctacagc tgttgctgcg
    13021 ctcggggtga ggacggaagg gtacgcgacc cgggacgact acgagcccgg tgggtagggg
    13081 attgccggtg cgccagggcc gcacggaacc ttcctcccgg gacgagggcg gaggaagccc
    13141 tgcgcaagcc aaaagttacc cggtgctgcg gagcgccctt gcgcggaggg gccgggagcg
    13201 acacgccccg gtgcggtgac cgcgatggac acagtgatga gctttcgtgg cccggagagt
    13261 ctccccaccg cttttgccca ctgctgtcga cagcacagga ggaacccgtg gctcagctct
    13321 tgagagtcca gaacttcacc atctcgagtg acggaatcgg tgccggtgcg gaccagagcc
    13381 tggagcgacc gttcggccat gtcgctcccg agcggctgtt cgcctgggcc ggcgccacgg
    13441 cgagctggcc catgcgcacc gaccccgggg gcagccgcgg cctcgacgac tacttcgccc
    13501 gggactacac acaccacatc ggcgccgaga tcatgggccg caacaagttc gggccgcagc
    13561 gcgggccctg gcacgaccct gagtggcgcg gctggtgggg ggacgagccc ccgttccaca
    13621 ccccggtgtt cgtgctgacc caccacgcgc gtccttcgtt cacgctctcc gacaccacgt
    13681 tccacttcgt cggcggcgac ccggccaccg tcctggagca ggcacgggag gccgcgcagg
    13741 gcaaggacgt gcgactcggc ggcggggtca gcaccatccg gcagttcctc gacgccgatc
    13801 tcgtcgacac cctgcatgtg gcggtcgcgc cggtgacgct gggatccgga cttcggctct
    13861 gggattcgcc cgacgagctg ctcgaccgct tccacctgga ggtcgtgccc agcccgagcg
    13921 gcagtgtcac ccaccacctg ttctggcgaa agtgagacca cggcccctag gggatgcccg
    13981 cacggccgat gcgggcgctg gggaccggcc cttacgggtc gaggccgccg ctgccctggg
    14041 ggccgtacag atcgagcagc cgggtgcggg tgccgtgcag ccggtcggcc accgtcttgg
    14101 ccacatagcg gtacatcgcc cggccgagga cggggtccgt ttcgcacagc tcgcggatcg
    14161 cccgggcgtc gaactccacg gcgtccaccg ggccgacggt ctccgctccc aggtgccaca
    14221 gaaagggcgg gaacatccag gaccagccga gcagttcgcc acggccgagg gtttccacga
    14281 ccgccgcccg gcgcccgggg acgtgctggt cgagcaccac ctgtccactg cggatgatcc
    14341 agaaccggtc cgcccgccgg ccctcctcga agagccgggt ggcgcgcggc agcgacacct
    14401 cgacggccat atcggtcagc tgccgtcgcc ggtcgggcgg caactcgtcg agcatatttt
    14461 cgatcatggt catgcgtcct ccgctcgctg cctgcacgat atgcggagct ttgcggggat
    14521 cgggggaatg gctcggcccg ccgggcatcg gcgggccgca accgggtccc ggtcaggtca
    14581 gctgacgccg taccagatcg tgcagccggc caccggtgtc ggcgagcagt tcggccgggg
    14641 ccccctgctc gacgatccgg ccctccgcca tcacgatcac acggtcggcg tccatgaccg
    14701 tggacagccg gtgggcgatc accagccggc tggcgctcag cttgcgggtg ctgtcgctga
    14761 cgatgcgctg ggtctcgttg tccagggcgc tggtggcctc gtcgaagaac aggatccgcg
    14821 ggcggcggac cagcgcctgg gcgatcatca ggcgctgccg ctgaccgccg gagatcgcgc
    14881 caccgccgga gatcatggtg tgcaggccca tcggcatccg cttgatgtcc tcggccagac
    14941 ccgccatctc ggcggccgcc caggcctctt cctgggtgaa ggcctcggcg ccgcagatgc
    15001 agtccaggat cgatccggtg agcggctggg cgttctggag cacgaccccg cactgccggc
    15061 gcaccgccgc ctggtccagg gcggccaggt cctggccgtc gtagagcaca ctgcccgagg
    15121 acggcttgtc gaagccgatg aggagccgca gcagggtcga cttgccgcag ccgctcgggc
    15181 cgacgacggc cacgaactca cccggctgga cccgcagcga gacatcatcg aggacgagcg
    15241 ggccgtcgtc ggtgtagcgg aacgagagct tcttggcctc gatgccgccg gacagggtgc
    15301 cgggctgggc gctggccccg cggacctccg gcttctcgtc cagcaccggc ttgatctgct
    15361 cgaacatcgg catcgcggcg gcggccgaga tgaacgcgcc ggtgatctgg gtgaccgccg
    15421 tcagcagcat ggtcaccgag gtgttgaagg tgaggaacga ggcggccgac atggtgccgc
    15481 gggccgggcc ggccagcaac atgaagaggg tgagtgagca gaccggcaga tagaccgcgt
    15541 tgaggacggt ggtcagattc ttgatccggc cggccttctg ctggagttcc cgggaacggg
    15601 cgaactcgcg ggcccaggcc gcgtacgcga agctctcggc cgccgcgacc cgcagtttgg
    15661 gcagcccgcg cagggtctgg aacgcctggt tgttgagctt gttaccgagc ttgaccagcc
    15721 gtcgctgcca gcgcagctcc cacaggccca tggcgaggaa caccgcaccg atcacgatca
    15781 gcatggcgac cgccgccagc gccagcggca cgctgtagac gagcagcagc accaggttca
    15841 tcgcgccgat agtggtggac tgcacggcca ccgggccgag accggacagc acccggcgga
    15901 tggcgctgat gcccatcgcg gcgctggcca gctcgccggt ggagcgttcg gtgaagaact
    15961 tcgtcggcag tcgcagcagc cggtcccaaa cggccggctg gagcgtgctc tcgatccggc
    16021 cctccatccg caggacggtg aggttctgca ggagcatgaa ggcggcggag accacgctgg
    16081 tgatcatgat ggccagggag gcctgcacga tcaggctctt gtcggcgctc ggtacgtact
    16141 ccccgagcac cttgccggtc gcgatcggga cgagggagcc gaggccgacg gtcaccagtc
    16201 cgctgagggc cagattgcgg acgtccatcc gggtcccgcg caggctgaag agcatcagcc
    16261 gccacaggct catgggccgt tccggcagcg ggcggtagaa catgacggcg cgcggttcga
    16321 gttcgtcggc gttgtccttg ccgaggcgca tccgcagccc ggagaccggg ttgaccgcct
    16381 cgtagcggcc gcggcgccac agcagcgcca ccggcgcgcc ggacttggcg cgatggccca
    16441 ccagggggcc ggtgttggtc cgccaccagg gcccctggag ccggaccgcc cgggtccgga
    16501 tccgcgagct gaccgcgatc cgttcgaccg gggtgatccg gtcgttgacg gcaccgccct
    16561 tgggcggctc ggtgagcgtg atacccgccg cctcggcgac cgtgcggcag accgcgaagg
    16621 tggtgtcgtc gctggtccgg tccgtcgtgc tactgccccg cccggcccgg ccgatggatg
    16681 ccaccagcgc ctggtcggcg cgctcgcgga cggtttcgcc cgccttgatt ccggccgccg
    16741 tacggtcctc gtgggcgcgc tccagctgct cgatccagcg gtcgacggcg ctcagcagcc
    16801 ggtactgctg attgaccatc tgctgccaca gctcggggtc caccagcaga tcgccggccg
    16861 cttccgcgtt gtaggacgcg ccgtactgca ccgtgccggg cgggaccggc atccacagga
    16921 tgtcgtcgtc ggccaccgcc tcgtcgccgg ggcggccgtc gagcggtgcc tcgaagagca
    16981 cgcccaggct gcgggcggtg cccagcgcga aggcgtgctc cagcgcggag ggcgcctcgc
    17041 cctggccgcc gtacgcgggg tcgttgccgt agccctgcgc gccgtattgc ggaaacgccc
    17101 cggtgtcgta ctccccgtac tcgtagcggg ggagttcgcg cagcgggata cggcgcagca
    17161 ggcagtcctg ggagggccgg ccgagcaggg tgtgctgcgg gcccgcgacc gggccgagca
    17221 gcagggtgcc cgcttcgagg cggccgagga agtgccagtg cccttcctgg gcggcgtcga
    17281 ccgcgaagag atcgagcgag ccgcccgtga cgagccacag cacatgcggg ccctccaggg
    17341 ggacgctgcg cagcccggtg cagtcgaccg gtgtgccgag gccgcccagc gcataggtga
    17401 cggcatcggt gtcgcccggt cccacgaccg tggacggggg tacggacacg tcagtgctcc
    17461 ttgaccagct cggcgtacgg gcccccggcg gcgaccaggt cctcgtgccg gccgcgttcg
    17521 acgaccaccc cgtggtcgag gacgacgatc tcgtcgctgt cgcggaccgt gctcagccgg
    17581 tgggcgatga tgacgcaggc gcagccgcgc cgccgcaggt tgtccatgat gatctgttcg
    17641 gtccgggcgt ccagtgcgct ggtgacctcg tcgaggacca ggatgctggg gcgccggacc
    17701 agggcgcggg cgatctccag ccgctgccgc tgcccgccgg agaagttacg gccgtcctgc
    17761 tcgacccggc tgtggatgcc gtcggggcgg ggggcgatca cctcgtcgta gagcgcggcg
    17821 tcctggaggg cggcgatcac cgcgtcgtcc gggatggacg ggtcccacag cgccacgttg
    17881 tcgcggaccg tgccctcgaa gaggaagatg tcctggtcga cgaaggagac ggaggcggcc
    17941 agcgcactgc gggagaggtc ctccagccgc tgtccgtcga tgcggatggt gccttcccag
    18001 gggctgtaga ggccggagat cagccgggag acggtggact tgccgctgcc ggagccgccg
    18061 acgagggcga cctgccggcc ggggccgacg gccagggaga agccggtgag cagcggtttg
    18121 tccagcgggc tgtagccgaa ggtgatgtcc tccagcgtca catggccctt gagccggcgg
    18181 ttgtcggcct ccggctcggg gcgcgagtag agggtgtcga cggggaagct ctcgacgtcc
    18241 ttgaggcggg ccacgtcggc ggcgaagtcc tggatccggc ccgccactcc gttgagccgg
    18301 gtgatgggcg cggtgaagcg ggtgaccagc gcctggaagg cgacgagcag accgatggag
    18361 atatggccct cgaccgcccg cagtccgccg atccacagga tcagcgcgct gttgagcgtg
    18421 gcgagggtgg gggcgaccac ggccagcgcg gcgctcggca cgcccagccg ctgctgttcc
    18481 tccagggtgg tggcgtgctg gccggcccag cggcggaagt agccgttctc gccgccggtc
    18541 gccttcatcg tctcgatgag ctggaggccc gtgtaggagg tgttggtcag ccgcgcggag
    18601 tcggcgcgca gcttctgggt gtgggtggcc cgcagccgga tcacgatccg catggcgacg
    18661 acattgagca gcgcgatgcc cacgccgatg acggtcagct gggggtcgta ggtccacagc
    18721 aggaaggcgt agaggatgac gacgatgccg tccacgcccg cggcggcgag gtcccgggcc
    18781 agcgtctcgg ccaccgcgtc gttggactgg agccgctgga ccaggtcggc cggactccgc
    18841 tgggcgaaga aggtgaccgg gagtctgagc agatggcgca ggaagcgggc gctggtgagg
    18901 gtggaggaga tgatgcggcc gcgcagcagg ttggcctgtt gcaggccggt cagtacggcg
    18961 gtcagcgcga ccatggcggc catcgacgcg aagagcggcc ccagcagcga ggtctggttg
    19021 ccgatcagga acatgtcgat gtacgtccgg ctgagcgcgg gcaccgccgc gccgaccgcg
    19081 accagcagca ggctggcgag cagcgcggcc agcagggtgc cggtggtacc gcgcatccgg
    19141 gcgggtacgg cgccgaggac gccgggcttg cggccgccct tgcggaagga ctcgccgggt
    19201 tcgaggacca gggcgacacc ggtgaagctg gtgtcgaagt cctccgtcgc cacgaagcgg
    19261 cggcccttgt cggggtcgtt gatgtggacg ccgcggcggc ccatgcggcg gcccgtgccg
    19321 tcgtagacga cgtagtggtt gaactcccag aacaggatgg cgggcgcctg cacctcggcg
    19381 agcgcggccg gctccatctg catgcccttg gcctggagtc cgtagctgcg ggcggccttg
    19441 agcagattgc tggcgcgcga gccgtcgcgg gagacaccgc aggcgatccg cagctcttcg
    19501 agcggcacat gccgtccgta gtgggccagc accatggcca gcgaggcggc gccgcactcc
    19561 acggcctcca tctggaggac ggtgggggtg cggacggtct tcgtcttctt gggcttcggg
    19621 gcgggcgcgg cccggcgggt gcggcgggcg ccgggcgcgg gttccgcgcg gcggcggccg
    19681 cggaccggcg gcggcaactg ctgctgcggg gcggcggagt cgtgcggggc ggtcacggca
    19741 gcagccaatc gatcgggtgc tgcgcggcca ggtggacggc gccactggcc ggcgtcatgg
    19801 agtcgacggc gtacggcggg ccgtcggagg tcgaccaggc gtagccggat ttgctgtgcg
    19861 ggacggcgtc gagctggacg aggaccgcga cgggctggcc gtgctgcgag aactcctcac
    19921 cgagctggct gctgcccagg aaggtgctga tccgctggcg ggactgggcg gtcctgccga
    19981 ccgctttgac ccggccgcgc agcacgccgt actgctgggt cggcacggac tggacggtga
    20041 ggtcgacgga cgcgccgacg gggacggtgg cgccacttcc ggccggtacg tacagcgtcg
    20101 ccatcagggg gtcgtcggtc cgggcgatgc gttccacgga ggccacatcc gctccggtcg
    20161 tgacgacgga gccgatggtg gcgaccatcg tggtcagccg gccggcggcg agcgtgcgga
    20221 cgacggtggt gccctgggcg gtacggaccc tcaggacggg ggtgtgggcg gccactcgct
    20281 tgccctcttc cgcgaggacg gcggtgacct ggcccgcgac cgggctctgg aggacgtagc
    20341 tgccctggcc gtgggtgagg atgccgggtg cgttcagggt ggacgacacg gtgccggtca
    20401 ccgcccatac ggagccggcg atcacgaaga ggaccgtgac ggtcagcgcg agccagccct
    20461 gggggcgggc gaaccgcacc ggaagatcga tctcttcggg cgattgcagt ttggaaaggg
    20521 cctgttggcg gaactgcacg acactcttcc ctcaactgca acgatctggt gcggacgggt
    20581 ggtggccggc gcccaggggc ccggatggag tccggggcac ctgggcagcc ggcccggcat
    20641 gtcggcaagg agggggcgcc gacctgccgt tgtcaccgtt caaagccggc tgtgccgctc
    20701 agcggcacag aaggggctca gagaccggcg accaggcccg tggcggtgcc gacgacgccc
    20761 gcggtgtcgg tgccggcgac accgtcgacc aggccggtgg cggtgcccac ggcgcccgag
    20821 accggggcga tggagtcaac ggtgttggtg gcggtgccga ccacgccgcc gacgaggcca
    20881 ccggacacgt tgtccaggtc gctgtcggag atttcctgcg tctgaacctg gggggtggag
    20941 ttcatgatga ttcccttcgg atgaatatct cgaaaaagct gcgcccgaac cgtccggtgg
    21001 ggggcccggc cgcagcagcg gcagtcgggt tcccgaaatc gggaaccggg gggtgactcc
    21061 cgcagtgcga aggatcaaag catgcaggcg cgttgcgctg ctaatcgggt agccgccgat
    21121 ccgggcgata tcaccctgtc gaaatacctg acgtgcacgc ccgtccatga cttggtggca
    21181 gcttcttcac atctcctccg gtttcttttc cggggcctcg gcaagcgtcc gttcggcgaa
    21241 ctggacattc cgtcaccaaa ccgctgagcc gcaggtcagc gtgggaatgt gacacggcag
    21301 agcgtgtgcc gactgcacat tcggtgtgca gattctttga agaccaccaa tttttacggc
    21361 acctcggcgc gatacggacg gacaactccg gcacatgctt gtgacgcagc cacgccgaat
    21421 gctgcagggg cattaagtgc gcccgattcg cccggagttc atgggcctta ttggcggtgc
    21481 tgaacgtatg gaatggactc atcgacgcta tccgtatgcc atttctgcgg aaacggatca
    21541 ggaacggatc gagtgaccgg acaacggaca taaccgcata acggagcacc gtcggacccg
    21601 tcggtaatgg gcgattggca ccaccgcacc ggcagcccgg tggcagccgc ccaccgggtg
    21661 gggcaccgtg agaaacgacg ctgcggggcc gcgccccggg aaggagccgt acgtggagcc
    21721 cgtggaggcg ctggagcgga tcgcctttct gctggagcgg cagggggccg tgacctaccg
    21781 cgtccaggcg ttccgtacgg ccgcgacggt gatcggcgcg ctgtccgccg acgagctgcg
    21841 cacccgtgcc cgcagcggct cgctggcgcg gctcaaagga ctggggccca agaccacccg
    21901 ggtgatcgag gaggccctca cgggcgcgcg gccggagtat ctgacgcacc ttgaggagga
    21961 ggcgggcggc ccgctggtcg agggggacca ggggcagcgg ctccgtcagg cactgcgtgg
    22021 cgactgccat ctgcactcgg actggtcgga cggcggcagt ccggtcgaga cgatggcgcg
    22081 ggccgcccgc gacctcggcc acacctggtg tgtgctgacc gaccactccc cccggctcac
    22141 cgtcgcccgc ggactgaccg ccgaacggct gcggcagcag ttgacgctgg tggcggaggt
    22201 gaacgagcgg ctggcgccgt tccggctgct gaccgggatc gagtgcgaca tcctcgacga
    22261 cggctcactc gaccaggagc cggagctgct ggagcagctc gatgtggtgg tcgcctcggt
    22321 gcactccaaa ctgcggatgg acaagcgccc gatgacccgg cggctgctgg ccgcggtccg
    22381 caatccgctg gtggacgtgc tcggtcactg caccgggcgg cagatcaccg gcaagctgcg
    22441 ccccgagtcg cagttcgacg ccggagaggt gttcgcggcc tgcgcagagc accacaccgc
    22501 ggtggagatc aactgccggc ccgaccgctt cgatcccccg cgccggctgc tccgcctggc
    22561 gctggagacc ggcaccctgt tctccatcga cagcgacgcc cacgcaccgg gccaactgga
    22621 ctggcagatc tacggctgcg cccgcgccga ggagtgcggc gtcccgcccg agcgggtcat
    22681 caacacctgg acggagcgcc agttggccac ctggacccgg accggccgga ccccgcaccg
    22741 ctgaccgctc tcccaccccg caggggcggt acgctcgcct cctcatggac acgcgcacgg
    22801 agcacgagat ggtcgccgtc ccaccggggc gggtgacgct gtcggaccgg cggacgcggc
    22861 gcagttggcc ggtcgagctg acgccctacc ggctcgcgcc gtgtccggtc acccaggaac
    22921 gctacgcaca ggtcaccggc gagcgcccga gcagcgcgcg gggcgaccgg ctgcccgtcg
    22981 agggcgtctc gtggtgggac gcggtccggt tctgcaatgc cctgtccgcg caggaggggt
    23041 tggcgcccgc gtaccgcctg gacaccgaca ccgagcggat cgagtgggac accgccgccg
    23101 acggctaccg cctgccgacc gaggccgagt gggagcacgc ctgccgggcc ggcacgacgg
    23161 cggcacggta cgggcggctc gacgacatcg cctggcaccg cggcaactcg cacgagcgga
    23221 tccacgaggt cggcggccgg cagcccaacg cctggggcct gtccgacatg ctgggcaatg
    23281 tgtgggagtg gtgctgggac gtctacgacg ccgaggtcta cggcagctac cgggtgctgc
    23341 gcggcggcgg atggttcgac gagcgctgga gctgccgggc gtctgtacgg cgccgcagcc
    23401 acccgacctt ccggatcgat gacgtgggct tccgtatcgc gcgttccctc tgacgggcgg
    23461 ggctccggcc tcgccgtcag gcggggtggg gcgcggtgga cggcaggtca ggtgcggtgg
    23521 ccggagtgag gcgcagcgcc accacgtacg cgacgaccac cgcgacgatc accagcggca
    23581 tcaccgtcag accgctcttc cccagcagca gtgtggccag cagcaccgag gtcatcggca
    23641 gccggagcat ggccacacac atcgcgccga cacccatcgc gaagcccgcg gtgagcgaca
    23701 gaccgggcag gtgggacagc acgacaccgc ccgccgcacc gaggaacagc gcggggaaga
    23761 tggggccgcc ccggaaggcg ctcagcgacg cgcagtacgc caggcccttg cacaggatga
    23821 ggagcagcag cgcgcccacc gtgtagcccg cgctgtcgcg gaacagcgac cccagcgccg
    23881 actggcccga atagagcatc tcggaggcgg gcttgccggt ggccgcggcg aacgccatcg
    23941 ccagtacgcc caccacgagg cccatcacga ccgtggccgg tacccggtgc cggacgacat
    24001 gccccttgag gtacagcgcc aggcgccgta cgccggacgc ggcgaacccg gcggccagcc
    24061 cgatgaccag cgcccagccg aactccggga tcgtcggccc ggcggccctg gggatgtcgt
    24121 gcagcgcgag cgagtaggtg ccgagcccgg tccagtcccc cagcccggtg aagatcagcg
    24181 ccccgaggcc ggaggccagc agacccggca ccagcacgat gcccagcatc gggccgccca
    24241 gccccgacac ttccatcagc aggaacgcgc ccaggagcgg ggagccgagc agggcgctga
    24301 tcgccgcgaa gctgccggcc gcgcccaccg cggcggcggc ctgggcaggc atgttgcggt
    24361 tcagcagccg tacggcgccc gcggccagcc cgccgccgag ggcgatgagc ggtgcctcgg
    24421 ggccgagcac cacgccgaag ctgagggagg tcagggccgc gaggaacaca ccggggagcg
    24481 cggagagcgg gggcgcgccc ttgagcgcca gcccgtcggc cggctcatgg cccccgccgc
    24541 cggggaggta acggacggtc agcccgacga ggagaccggc gatcagcagc atcgggaccg
    24601 gccaccagat gggggtgccg gtgaagccga gggcccgcgg caggtcgtgg tagatcagcg
    24661 gttccagctc gtggaccagc gcgagaaagc cgaacgcgac ggcgcagacc gggaagccga
    24721 tcgcgcccgc caccagcagc agcttgagat agccgcgggt gcgcaccagc gcgtaggggt
    24781 cctgcggcgc ggtggtcggt gttccgccca ccgggccggc cgggccgacc gacatgcgcc
    24841 tcgcctcctc ggaaccgggg ctgccccggc gcccgcccgg gtcgccgcgg tgacgagcct
    24901 gtcacggccg gtccgggccg gcacctcggg cgcggccggg cggggcacgg cgggtccggc
    24961 cctccgtggc ggcagttgat gacgggacag ccctcacccc tgcgaggccg ccgcctcccg
    25021 gagggcggcg agcaccgggc ggaacagcgg gtgctcctcg gctccgcggc gtaccgcggc
    25081 gaagacccgg cgggtggggg ccacatcgtc gacggggcgg accaccaccc ccgtgaggtc
    25141 catgtcgcgc agcgccgagc gggggacgag ggccacgccc gccgcggccg aggcgagcgc
    25201 gacgacggcg cggaagtcgt cggaggtgtg ctccaggcgc ggctggaaac cggcgtattc
    25261 gcaggccagg accaccacgt cgtggcaggg gttgccggga taggggccga tccaggggtc
    25321 gccggcgaga tcggcgaccg ccagccggtc cgtgtcggcg aggcggtggc cgggcggcag
    25381 gaccgcgtcg aacggctcgg cgtagagcgg gacccgggtc agccgcgggt cgtcggcacc
    25441 cggtgcgccc cggtattcga cggccaccgc cacatcgacc tgccggtcga ggaccatcag
    25501 caggctggcg tcgccctcgg cgtcctggac gtggacccgg atgccggggg cggtgcgggc
    25561 gagggcggtg agcgcgggcg cgacgaccag gccgatgccg gtggcgaagg ccgcgacggt
    25621 caccgtgccc gcctcgcccg agccgtaggc ggcgagctcg gactcggcgc gctccagctg
    25681 tgccaggacg gcgttggcgt gggtgagcag gatgtcgccc gcggcggtca gccggacgcc
    25741 gcgggcgctg cgctccacca gacggtggcc ggtctcctgc tccagggcgg ccagctgctg
    25801 ggagaccgcc gagggcgtga gatagagcgc ggcggccgcg gcagtgaccg tacggtggtc
    25861 ggccaccgca cggaggatgt gcagccgtcg tgcttcgatc atgcttccag tctcgcagga
    25921 gccgcccgcg ggcggtgtca gcccc
//
