LOCUS       NZ_CP050976            36006 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1089964
            Orig. end                         :: 1125970
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..36006
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="6"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..36006
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..36006
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:21006](+)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15001..21006
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     gene            116..1135
                     /locus_tag="HEP86_RS04980"
                     /old_locus_tag="HEP86_04980"
     CDS             116..1135
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670920.1"
                     /locus_tag="HEP86_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_04980"
                     /product="asparaginase"
                     /protein_id="WP_168477630.1"
                     /transl_table=11
                     /translation="MSQRTTLPPHRTAGAPPAVREPAHVPVADVMRAGIVEGVHHGSVV
                     VLAADGSVAFQAGDIEAAFYPRSALKPVQAVGLLRAGLPPLDDPSLALVAASHSGEEQH
                     LATARGILAAGDLTEDELRNVPDLPYDPAVRDEWIRRGLGPTRLAQNCSGKHAAMLLTC
                     RTRGWDLDGYLDPGHPLQRELAAAVEDLTGQGIARVTVDGCGAPLFSVSLHGLTRAAAR
                     LATAAPGTGEGRVAHAMRTHPEMVSGSRRDVARLVRAVPGLLAKDGFEGVQIAALPDGR
                     AVGVKIADGGDRARMPVTAAALAHCGVDPDALAPFATTPVIGGGTPVGSLRATKALAP"
     gene            1224..2645
                     /gene="aspA"
                     /locus_tag="HEP86_RS04985"
                     /old_locus_tag="HEP86_04985"
     CDS             1224..2645
                     /EC_number="4.3.1.1"
                     /GO_function="GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aspA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573941.1"
                     /locus_tag="HEP86_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_04985"
                     /product="aspartate ammonia-lyase"
                     /protein_id="WP_168477632.1"
                     /transl_table=11
                     /translation="MTSAGHRREHDLLGDREIPAEAYWGVHTLRAVENFPITGTPIATY
                     PHLINALAAVKEAAARANQDLGLLDTERADAIAAACREIRSGGQLHDQFVVDVIQGGAG
                     TSTNMNANEVIANRALEILGHDKGDYRHLHPNEHVNLSQSTNDVYPTAVNVATIIAVRE
                     LLDSMAVLREAFAAKAEEFRDILKMGRTQLQDAVPMTLGQEFSAYAVMLEEDQSRLAEA
                     VLLIHEINLGATAIGTGLNAPKGYAEAARTHLAALTGLPLVTAANLVEATQDCGAFVHL
                     SGVLKRIAVKLSKSCNDLRLLSSGPRAGLAEINLPPVQAGSSIMPGKVNPVIPEVVNQV
                     AFEVIGNDVTITMAAEAGQLQLNAFEPVILHSLSESITHLGAACRTLAERCVAGITANT
                     ETLLASVQNSIGLVTALNPHIGYTAATAIAKEALATGRGVAELVLEQGLLPADRLAALL
                     RPEEIAGTGGDLSTV"
     gene            2959..3753
                     /locus_tag="HEP86_RS04990"
                     /old_locus_tag="HEP86_04990"
     CDS             2959..3753
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541032.1"
                     /locus_tag="HEP86_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_04990"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_168477634.1"
                     /transl_table=11
                     /translation="MRIALCQMTATTDPKENLAIVQDQVRRAAREGARLAVLPEAAMVR
                     FGAALGQVAEPLDGPWAEGVRAVARETGVTVVAGMFTPADDGRVTNTLLATGPGVEEFY
                     DKIHLYDAFGFRESEAVAPGKRVVTIDVDGVRVGLATCYDLRFPELFRAHADAGATVSV
                     LPAAWAAGPGKRAQWDLLVRARALDATVWLAAVNQAAPDPQADPEAPTKAPTGVGHSAL
                     IGPDGTVRGQLGDRPDLLVGDVDTEETARVRRAVAVLDNRSM"
     gene            complement(3822..4463)
                     /locus_tag="HEP86_RS04995"
                     /old_locus_tag="HEP86_04995"
     CDS             complement(3822..4463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579723.1"
                     /locus_tag="HEP86_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_04995"
                     /product="LUD domain-containing protein"
                     /protein_id="WP_168483548.1"
                     /transl_table=11
                     /translation="MVTATARETVLGRVRDALALSDGPEVTVPRGYRTGRSLPDEERLA
                     LFADRLVDYRAQVRTCTAATTATVLAEVLHAHGARKIGLPQGLDPAWLAGYDGETVTDS
                     ADVPAPSLDALDGVVTGSAVSCAETGTIFLDGAAADQGRRALTLVPDLHVCVVELSSVR
                     TGVPEAVAQLTPEHPITLISGPSATSDIELERVEGVHGPRTLAVVIRTDR"
     gene            complement(4457..6046)
                     /locus_tag="HEP86_RS05000"
                     /old_locus_tag="HEP86_05000"
     CDS             complement(4457..6046)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057943.1"
                     /locus_tag="HEP86_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05000"
                     /product="lactate utilization protein B"
                     /protein_id="WP_168477635.1"
                     /transl_table=11
                     /translation="MSSPNGPATQGTFLGMPAVPPRSPYGTGHLRGERSFPRAAHDELG
                     NGQLRRNLGKATHSIRAKRLAVTGELPDWEQLRDTGSAIKTDTMNRLPELLEQLERKVT
                     ERGGTVHWARDGVEANEIVTRLVRDTGSDEILKVKSMATQEIGLNEHLATQGIAALETD
                     LAELIVQLADDRPSHILVPAIHRNREEIREIFLRHLPGVDPALNADPARLAAAARAFLR
                     EKFMTTQVAVSGANFGIAETGTLAVVESEGNGRMCLTLPETLITVMGIEKVLPRFQDLE
                     VFLQLLPRSSTGERMNPYTSLWTGVTPGDGPQEFHLVLLDNGRTAALADRIGRAALHCI
                     RCSACLNVCPVYERTGGHAYGSTYPGPIGAVLTPQLAGMHGAKGDPNSSLPYASSLCGA
                     CFDACPVKIDIPSLLVELRHQHTEQSGTTAEKLAMKAAAAVMKRPGLFTAAQKAAGLGR
                     VPAGRDGTLSRLPPPLNGWSDSRDTPAPPRQTFRSWFASAEGAAAMRAAAEEGARHTDD
                     APHTDDAPQEES"
     gene            complement(6043..6810)
                     /locus_tag="HEP86_RS05005"
                     /old_locus_tag="HEP86_05005"
     CDS             complement(6043..6810)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049720.1"
                     /locus_tag="HEP86_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05005"
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_168477637.1"
                     /transl_table=11
                     /translation="MRIALFATCLGDTLFPEAVKSTAVLLARLGHDVVFPPQQTCCGQM
                     HVNTGYQREPVPLVRNFAEQFGDPAIEAVVVPSGSCAGSVRHQHEIVAARYGDAALRAG
                     VAAVRTKTYELSEFLVDVLDLTDVGAYFPHRVTYHPTCHSLRMLRVGEKPLRLLRAVEG
                     IDLVELPEADACCGFGGTFAVKNAETSTAMLRDKMDHITGTGAAVCTAGDSSCLMHIGG
                     GLSRIRSGTRTLHLAQILAATRTAPHVLTEAAR"
     misc_feature    complement(6920..6938)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.21"
                     /tool="antismash"
     gene            7017..8690
                     /locus_tag="HEP86_RS05010"
                     /old_locus_tag="HEP86_05010"
     CDS             7017..8690
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641387.1"
                     /locus_tag="HEP86_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05010"
                     /product="L-lactate permease"
                     /protein_id="WP_211117285.1"
                     /transl_table=11
                     /translation="MATTPPAALAAYTPDVAAVGDSLTTTALLGLVPLATFFLLLMAAR
                     RSALHSALGALLTALLVAVLGYGMPLRLGALSATQGAAFGLFPVMLIVVSAIWFYELTV
                     VSHRFDDLRRSFNAVGRGDLRIQAMLITFCFGGLLEALAGFGAPVAITAAMLMAVGLPR
                     LTSAVTVLVANTAPVAFGAMAIPITTAGNLTGIPAESLAAVIGRQSPLLALFVPQLLLF
                     LVDGWRGLRQLWPIALATGAVFALAQFWCSAHFAYELTDVVAALAGFGAAVVMLRFWTP
                     TTPDDQRSQVTAEPLTRRRTFLAVLPYLLVIAVFALAKLDIGGLDIPGLLGSLTVQLDW
                     PGLYGNLLAPDGSPAGSAVYKLEVLANPGTLLLLSGLLVMLIYSRAKDADRFPMTARSG
                     LSCAGRTLRNMRTAIATVATVMALSYVMNQSGQTLAIGTWLAAAGGLFALLSPVLGWLG
                     TAVTGSDTSSNALFATLQQTAGKTAGIDPTLLVAANTTGGVVGKLISPQNLTIAATAVE
                     QPGTERILLRKVAGYSVAMLAVLCVLVYLQSLPVLSWMLP"
     gene            complement(8771..9181)
                     /locus_tag="HEP86_RS05015"
                     /old_locus_tag="HEP86_05015"
     CDS             complement(8771..9181)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002027.1"
                     /locus_tag="HEP86_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05015"
                     /product="VOC family protein"
                     /protein_id="WP_168477642.1"
                     /transl_table=11
                     /translation="MGSQLNPCLAFNGNARQAIEFYQDVLGGQLDMGTYAEYGSPDVPH
                     PDKIMHATLRTPDGYTLMAWDVREEMPHTPGNNVAVFLDGDDAKLRDYFERLSAGGTVT
                     LPLEKQSWGDEAGSLVDQFGITWMVNITQQPR"
     gene            complement(9306..10774)
                     /locus_tag="HEP86_RS05020"
                     /old_locus_tag="HEP86_05020"
                     /pseudo=""
     CDS             complement(9306..10774)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353223.1"
                     /locus_tag="HEP86_RS05020"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05020"
                     /product="NF041680 family putative transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLNHDARRDAFDFTSHFREDFYACLTRRGDTLFELCDAMLCENGP
                     VTSPVDLTLLAEHRRGHGALYDALNCGRIAADRLRRTLAVLPQPKAADNRLALAVDVTN
                     WLRPDAPCSPDRLFCHVYGRNGRSSDQFIPGWPYSFVAALETGRTSWCQLLDAVRLGPD
                     DDVAEVTAAQVRRVVTDLIDGGQWEPGDADILVVFDAGYDAPRMAYLLDGLPIEVLGRM
                     RADRVMRRPAPSRKEFALANPYGGRYPRHGNEFRFAKPETWGEPDAATMQVTDRYGTAQ
                     AIAWDRIHPRLTTRSAWIDHEGELPLLEGTLIRLQVDHLPGVRTRCPSGCGPRRPV"
     misc_feature    complement(10819..10832)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.47"
                     /tool="antismash"
     misc_feature    10900..10913
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    10907..10927
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    11134..11150
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            complement(11186..12211)
                     /locus_tag="HEP86_RS05025"
                     /old_locus_tag="HEP86_05025"
     CDS             complement(11186..12211)
                     /NRPS_PKS="Domain: PKS_ER (19-266). E-value: 1.2e-11.
                     Score: 36.2. Matches aSDomain:
                     nrpspksdomains_HEP86_RS05025_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433259.1"
                     /locus_tag="HEP86_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05025"
                     /product="alcohol dehydrogenase"
                     /protein_id="WP_168477644.1"
                     /sec_met_domain="ADH_N (E-value: 1.2e-27, bitscore: 94.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.8e-20, bitscore:
                     71.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHRVAQVAAPGGTFEIVEREVPEPGPGHVRVAVDACGICHSDA
                     AFVDAAFPGVRFPLVPGHEIAGRIDELGEGAQSRGWHAGERVTVGWFGGSCGHCTPCRQ
                     GDFIVCENLKVPGWAYDGGFAETMIAPMDALARTPDALASTDAGPLACAGVTTYNGLRR
                     SSGRPGDLVAVLGLGGLGHLGVQYAAAMGFETVAIARGTAKADLAKQLGAHHYIDSTAD
                     TTVADALRSLGGAKVVLATAGSSDAITATVDGLSHRGELVVIGAAFEPMGISPVQLILQ
                     GRIVRGHPSGTAQDVHDTMAFSTLHGIRPMTEIMPLDQADEAYQKMLSGAVRFRMVLTT
                     R"
     aSDomain        complement(11414..12154)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05025_PKS_ER.1"
                     /evalue="1.20E-11"
                     /label="HEP86_RS05025_PKS_ER.1"
                     /locus_tag="HEP86_RS05025"
                     /protein_end="266"
                     /protein_start="19"
                     /score="36.2"
                     /tool="antismash"
                     /translation="EREVPEPGPGHVRVAVDACGICHSDAAFVDAAFPGVRFPLVPGHE
                     IAGRIDELGEGAQSRGWHAGERVTVGWFGGSCGHCTPCRQGDFIVCENLKVPGWAYDGG
                     FAETMIAPMDALARTPDALASTDAGPLACAGVTTYNGLRRSSGRPGDLVAVLGLGGLGH
                     LGVQYAAAMGFETVAIARGTAKADLAKQLGAHHYIDSTADTTVADALRSLGGAKVVLAT
                     AGSSDAITATVDGLSHRGELVVIGA"
     misc_feature    complement(12585..12599)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(12618..13400)
                     /locus_tag="HEP86_RS05030"
                     /old_locus_tag="HEP86_05030"
     CDS             complement(12618..13400)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010279273.1"
                     /locus_tag="HEP86_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05030"
                     /product="FCD domain-containing protein"
                     /protein_id="WP_168477646.1"
                     /transl_table=11
                     /translation="MTAEWRPVRQSRTHELVLERIEERVLAGELKAGDRLPPERELAPV
                     LGVSRSALREALRVLETIGVLVAQPGRGPDAGARIVRNPDDALGRLLRLHFALGSYRLH
                     DVLEARVVLERSSFEAAAEHASARDLDEAEALLDRMREPGVGAADFNDLDTRFHVAIAR
                     SSGNQLTSTLTSAVRESVRPLILRALETAEDWPATAAALNAEHTELLRLVRAGKGAKAA
                     DLAETHIRGFHGRLVDENAPAEQEQEQEDEGRAGADSP"
     gene            complement(13544..13834)
                     /locus_tag="HEP86_RS05035"
                     /old_locus_tag="HEP86_05035"
     CDS             complement(13544..13834)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024881.4"
                     /locus_tag="HEP86_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05035"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_168477648.1"
                     /transl_table=11
                     /translation="MSAAEDPHEAVGAYVLHALPPEEAAAFATHLASCDACTREVADLE
                     ATVACLADAEAVTPPDALRRRVLDRIATTAQEQLLRREPTRRDGPRLDLEV"
     gene            complement(13834..14427)
                     /gene="sigK"
                     /locus_tag="HEP86_RS40335"
                     /old_locus_tag="HEP86_05040"
     CDS             complement(13834..14427)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="sigK"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319092.1"
                     /locus_tag="HEP86_RS40335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05040"
                     /product="ECF RNA polymerase sigma factor SigK"
                     /protein_id="WP_266735633.1"
                     /transl_table=11
                     /translation="MSHTAPEGPRPPERSAADRLVDELLVRVALGDEPAFVGVYDALVV
                     PVMGLAYRILRDEAQAEEVTQDVMIEVWRKADRFRPERGAAKSWVLTLAHRRAVERVRS
                     VRAGAERERKAAQLAHQTPFDEVVEAVEEREERAQVYRCLAGLGNSQRLPLVLAYYQGL
                     TYAEVAEALSTPAGTVKTRMRTGLRRLRVCMGGD"
     misc_feature    complement(14988..14997)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            15001..17433
                     /locus_tag="HEP86_RS05045"
                     /old_locus_tag="HEP86_05045"
     CDS             15001..17433
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (2-63). E-value: 3.3e-10.
                     Score: 32.1. Matches aSDomain:
                     nrpspksdomains_HEP86_RS05045_PP-binding.1"
                     /NRPS_PKS="Domain: TIGR02353 (96-797). E-value: 1e-233.
                     Score: 769.5. Matches aSDomain:
                     nrpspksdomains_HEP86_RS05045_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574928.1"
                     /locus_tag="HEP86_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05045"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_248001570.1"
                     /sec_met_domain="PP-binding (E-value: 2.8e-08, bitscore:
                     33.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 1.3e-231, bitscore:
                     769.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAEVMGTGQTPVDRHFFDDLGADSLVMAHFCARVRKRADLPPV
                     SMKDIYRYPTIRALATALAGSPPSLPVETPPPAPTPPSAPAPAVRGTSRYVLCGALQLL
                     MFLGYTSLVAVATAWGYEWIAAGSGVFGRYLRSVLCGAAGLLLLCAFPILVKWVLIGRW
                     KPRQFRVWSLPYVRFWVVKTLIRANPLVLFVGSPLYTLYLRALGARIGRGVAVFSRNVP
                     VCTDLLALGDGTVVRKDAFLNCYRAQAGVVQTGAVVLGKNVVISEATVLDIETALGDGA
                     QLGHASSLHSGQVVPDGEHWHGSPAQRTDVDYRVVKPARCGAVRRTVHSAVQLVTVLLL
                     YVPLAVGGVSILLAEAPQLSAVLEPGPTALADGSFYVDALLVSLLFFAAVPLGLLFQAT
                     VPRLLSRTLTPGKVYPLYGFHYGVQRLIALTTNRKFLMRLFGDSSAIVHYLRGLGYDLS
                     RIEQTGSNFGTEVKHETPYLSSVGSGTMVADGLSVMNADFSDTSFRVCRTSIGPRNFLG
                     NRIAYPSRGKTGDNCLLATKVMVPVDGEVREGVGLLGSPSFEIPRSVQRDSTFDQLKNG
                     EQLRRHLAAKNRHNAATMGLYLLVRWLYFFWATLLVAVAAELYDSVGALAIALGNVLVL
                     VSGVVYFVLVERAVTVFHPLSPLFCSIYDPRFWRRERFWKVPSESYLLLFNGTPFKNLI
                     WRLLGVRIGRRVFDDGCYLTERTLAAIGDGCTLNVGSVVQCHSQEDGTFKSDRSTLGAG
                     CTLGVGAFVHYGVALGDGAVLAPDSFLMKGEAVPPDAHWGGNPARQTSGQDTGEGWR"
     aSDomain        15007..15189
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05045_PP-binding.1"
                     /evalue="3.30E-10"
                     /label="HEP86_RS05045_PP-binding.1"
                     /locus_tag="HEP86_RS05045"
                     /protein_end="63"
                     /protein_start="2"
                     /score="32.1"
                     /tool="antismash"
                     /translation="LAEVMGTGQTPVDRHFFDDLGADSLVMAHFCARVRKRADLPPVSM
                     KDIYRYPTIRALATAL"
     aSModule        15007..17391
                     /domains="nrpspksdomains_HEP86_RS05045_PP-binding.1"
                     /domains="nrpspksdomains_HEP86_RS05045_TIGR02353.1"
                     /incomplete
                     /locus_tags="HEP86_RS05045"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        15289..17391
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05045_TIGR02353.1"
                     /evalue="1.00E-233"
                     /label="HEP86_RS05045_TIGR02353.1"
                     /locus_tag="HEP86_RS05045"
                     /protein_end="797"
                     /protein_start="96"
                     /score="769.5"
                     /tool="antismash"
                     /translation="LCGALQLLMFLGYTSLVAVATAWGYEWIAAGSGVFGRYLRSVLCG
                     AAGLLLLCAFPILVKWVLIGRWKPRQFRVWSLPYVRFWVVKTLIRANPLVLFVGSPLYT
                     LYLRALGARIGRGVAVFSRNVPVCTDLLALGDGTVVRKDAFLNCYRAQAGVVQTGAVVL
                     GKNVVISEATVLDIETALGDGAQLGHASSLHSGQVVPDGEHWHGSPAQRTDVDYRVVKP
                     ARCGAVRRTVHSAVQLVTVLLLYVPLAVGGVSILLAEAPQLSAVLEPGPTALADGSFYV
                     DALLVSLLFFAAVPLGLLFQATVPRLLSRTLTPGKVYPLYGFHYGVQRLIALTTNRKFL
                     MRLFGDSSAIVHYLRGLGYDLSRIEQTGSNFGTEVKHETPYLSSVGSGTMVADGLSVMN
                     ADFSDTSFRVCRTSIGPRNFLGNRIAYPSRGKTGDNCLLATKVMVPVDGEVREGVGLLG
                     SPSFEIPRSVQRDSTFDQLKNGEQLRRHLAAKNRHNAATMGLYLLVRWLYFFWATLLVA
                     VAAELYDSVGALAIALGNVLVLVSGVVYFVLVERAVTVFHPLSPLFCSIYDPRFWRRER
                     FWKVPSESYLLLFNGTPFKNLIWRLLGVRIGRRVFDDGCYLTERTLAAIGDGCTLNVGS
                     VVQCHSQEDGTFKSDRSTLGAGCTLGVGAFVHYGVALGDGAVLAPDSFLMKGEAVPPDA
                     HWGGNPA"
     gene            17452..21006
                     /locus_tag="HEP86_RS05050"
                     /old_locus_tag="HEP86_05050"
     CDS             17452..21006
                     /NRPS_PKS="Domain: AMP-binding (239-643). E-value:
                     1.4e-101. Score: 332.0. Matches aSDomain:
                     nrpspksdomains_HEP86_RS05050_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (751-817). E-value: 4e-18. Score:
                     57.4. Matches aSDomain: nrpspksdomains_HEP86_RS05050_PCP.1"
                     /NRPS_PKS="Domain: TauD (883-1166). E-value: 2.5e-45.
                     Score: 147.2. Matches aSDomain:
                     nrpspksdomains_HEP86_RS05050_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123298.1"
                     /locus_tag="HEP86_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05050"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_168483549.1"
                     /sec_met_domain="AMP-binding (E-value: 7.1e-108, bitscore:
                     359.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.1e-10, bitscore:
                     38.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TauD (E-value: 3.3e-43, bitscore: 147.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARTRGDRGGSADGAYTRVPRWTRVPVPGTAEHLTALPEQLPAA
                     LRRVADRLRMPLSSVLLAAHAKVLAVLSGDQEVTTGYLAERGGTPLPSRLTTAAGSWRT
                     LLLDTHRAEVELLRRRGFPAAGTGPEPAPAEESPETVFDLPGADGGPAGETVLWVALVR
                     HDGREVLRLRYRTEVLDAGCAARIGGYYRTALTLLAADPDADHRRQSLLSAEELRCQLE
                     GLAGPSRPLPDRRFHELFQQRVREHPDTIAAVHGSRRWTYRELNVRANRLAHALLARGL
                     AREDVVAVVTERNLEWLAAVIAIFKAGGVYLPVEPHFPPGRIALMLSRAGCRQVLTEPG
                     STAGLDRARTSVPGVRTLFIDAVCAASPADSDPEVRVGPDQLAYIYFTSGSTGEPKGAM
                     CEHLGMLNHLYAKIDDLAIDEGQVVAQTAPQCFDISLWQLLSALLVGGRTLLVEQAAVL
                     DVGRFLDTVGAGRATVLQVVPSYLDVVLSALAQRPGALPDLRCVSVTGEALKKELVQRW
                     FAARPGIRLVNAYGLTETSDDTHHEVMDAVPDSERVPLGRPVNNVRVYVVDEHLAPVPL
                     GAPGEIVFSGVCVGRGYINDPERTRLAFVPDPHHPGRRLFRAGDHGRWLPDGKLEFLGR
                     RDSQVKIRGFRIEMGEIENALLRVPGVGDGTVVVTQRAGRGKRLVAFYSGRHALAADVL
                     RGRLGELLPEYMVPSAFLWRESLPLTANGKIDKKALEALAGGLDTVEDDYHAPRTPTER
                     QLAAAWAEVLGIPQDRIGRQDNFFDCGGTSLSAVALAVCLGRAVSVKDLTRHPVLADLA
                     RQVDARAGRPQPHPNDAAQAVRCDTARPAASRAATERRTTMVSSLSISLPELEREPGTP
                     PMLRVGTTDSAARWAAERRDALRAVVAEHGAVLIRGLGMRDPAGVGAVLHGLGVAPLTE
                     REAFALRQTYSEGVYSSSKWPPNQPMCMHHELSYTLEFPGLMLFACLGAPTTGGSTGVA
                     DSAAVLDALPPVLTERFEREGWLLTRSYHPEIGATLDQAFGTEDRDAVERYCRAHAIDF
                     TWQPDGGLRTTQHRSAVLHHPVSGRRCWFNQIAFLNEWTMAPEVREYLIDEYGPDGLPF
                     NTRYGNGDPLAEDVVQQLNEVYDAHTARRPWEAGDLLLVDNVRSAHSREAFEGPRDVVV
                     ALADPVRLADCAPTVEVN"
     aSDomain        18169..19380
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05050_AMP-binding.1"
                     /evalue="1.40E-101"
                     /label="HEP86_RS05050_AMP-binding.1"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="643"
                     /protein_start="239"
                     /score="332.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FQQRVREHPDTIAAVHGSRRWTYRELNVRANRLAHALLARGLARE
                     DVVAVVTERNLEWLAAVIAIFKAGGVYLPVEPHFPPGRIALMLSRAGCRQVLTEPGSTA
                     GLDRARTSVPGVRTLFIDAVCAASPADSDPEVRVGPDQLAYIYFTSGSTGEPKGAMCEH
                     LGMLNHLYAKIDDLAIDEGQVVAQTAPQCFDISLWQLLSALLVGGRTLLVEQAAVLDVG
                     RFLDTVGAGRATVLQVVPSYLDVVLSALAQRPGALPDLRCVSVTGEALKKELVQRWFAA
                     RPGIRLVNAYGLTETSDDTHHEVMDAVPDSERVPLGRPVNNVRVYVVDEHLAPVPLGAP
                     GEIVFSGVCVGRGYINDPERTRLAFVPDPHHPGRRLFRAGDHGRWLPDGKLEFLGRRDS
                     QVKIR"
     aSModule        18169..19902
                     /complete
                     /domains="nrpspksdomains_HEP86_RS05050_AMP-binding.1"
                     /domains="nrpspksdomains_HEP86_RS05050_PCP.1"
                     /locus_tags="HEP86_RS05050"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       18358..18393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05050_0001"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="314"
                     /protein_start="302"
                     /score="11.2"
                     /tool="antismash"
                     /translation="AIFKAGGVYLPV"
     CDS_motif       18598..18657
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05050_0002"
                     /evalue="5.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="402"
                     /protein_start="382"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYIYFTSGSTGEPKGAMCEH"
     CDS_motif       19174..19263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05050_0003"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="604"
                     /protein_start="574"
                     /score="36.4"
                     /tool="antismash"
                     /translation="PLGAPGEIVFSGVCVGRGYINDPERTRLAF"
     CDS_motif       19345..19410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05050_0004"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="653"
                     /protein_start="631"
                     /score="36.0"
                     /tool="antismash"
                     /translation="FLGRRDSQVKIRGFRIEMGEIE"
     aSDomain        19705..19902
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05050_PCP.1"
                     /evalue="4.00E-18"
                     /label="HEP86_RS05050_PCP.1"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="817"
                     /protein_start="751"
                     /score="57.4"
                     /tool="antismash"
                     /translation="ERQLAAAWAEVLGIPQDRIGRQDNFFDCGGTSLSAVALAVCLGRA
                     VSVKDLTRHPVLADLARQVDA"
     aSDomain        20101..20949
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05050_TauD.1"
                     /evalue="2.50E-45"
                     /label="HEP86_RS05050_TauD.1"
                     /locus_tag="HEP86_RS05050"
                     /protein_end="1166"
                     /protein_start="883"
                     /score="147.2"
                     /tool="antismash"
                     /translation="RWAAERRDALRAVVAEHGAVLIRGLGMRDPAGVGAVLHGLGVAPL
                     TEREAFALRQTYSEGVYSSSKWPPNQPMCMHHELSYTLEFPGLMLFACLGAPTTGGSTG
                     VADSAAVLDALPPVLTERFEREGWLLTRSYHPEIGATLDQAFGTEDRDAVERYCRAHAI
                     DFTWQPDGGLRTTQHRSAVLHHPVSGRRCWFNQIAFLNEWTMAPEVREYLIDEYGPDGL
                     PFNTRYGNGDPLAEDVVQQLNEVYDAHTARRPWEAGDLLLVDNVRSAHSREAFEGPRDV
                     VV"
     gene            21010..22080
                     /gene="sbnB"
                     /locus_tag="HEP86_RS05055"
                     /old_locus_tag="HEP86_05055"
     CDS             21010..22080
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995200.1"
                     /locus_tag="HEP86_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05055"
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_168477654.1"
                     /transl_table=11
                     /translation="MTTVRPTPSRPTPPGPPPAPSFAVISGAQVQQALEGREKEIVDVV
                     EATYRLHGAGESVNPPSSFLHLPDRPSSRIIALPASIGGRTRVDGLKWISSFPPNVAAG
                     IPRASAVLILNDHDTGYPFACLESSIISATRTAASAASAADRLSRGRPRPTRVGFFGAG
                     LIARYIHTFLEGTGWSFDEIGVHDLSAESAAGFRLYLEQCRTTGRVTVHHSAEELIRSS
                     DLLVFATVAPQPHVHEVAWFGHHPVVVHVSLRDLAPQILLASTNIVDDIEHCLRAGTSP
                     HLTEQLTGNREFLHGTLDDVLAGRVAVPADRTAVFSPFGLGVLDLAVGKYVYDEVVRSG
                     ELRVVDGFFHELRRYG"
     gene            22138..23193
                     /gene="sbnA"
                     /locus_tag="HEP86_RS05060"
                     /old_locus_tag="HEP86_05060"
     CDS             22138..23193
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892108.1"
                     /locus_tag="HEP86_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05060"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_168477656.1"
                     /sec_met_domain="PALP (E-value: 1.2e-47, bitscore: 161.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVISAPYAFNEEELYVDLRSIFGHSLFLKCEGFNFAGSIKLKAA
                     TEMVESAERAGDLRPETVLVESSSGNLGVALSMIAASKGYRFLCVTDSRCNLATRLMME
                     ALGSQVHVVADQESNGGFLGARLAYIRNLCASDDRCLWLSQYTNPSNWKAHYRRTAPAI
                     ARAFPRLDLLFVGAGTTGTLMGCARYFREWHRAVRIIAVDSVGSVTFGGTPGHRMIPGL
                     GMSVQPPLLDESYVDDVVRVEEADTIRTCHRLAKRGFVFGGSTGTVVSGATDWLTRHDA
                     HDRTAVAIAPDLGERYLDTVYHDNWVQDLYGEHVLDPAPPVNADVAPLGPTSPAEPPEP
                     SPRRRQRRHDA"
     gene            complement(23287..24456)
                     /locus_tag="HEP86_RS05065"
                     /old_locus_tag="HEP86_05065"
     CDS             complement(23287..24456)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541030.1"
                     /locus_tag="HEP86_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05065"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_168477657.1"
                     /transl_table=11
                     /translation="MTTTPTESSPAPTTPATAAAPSLIATLAGHHYTDPGIFRQEQEKI
                     FERLWFCAVRSADLEKPGAFRTVRIGRESVLITRNRAGALRAFLNICRHRGAQLCTEES
                     GEVRRNLQCPYHAWTYDLDGRLVAAPNLQKMPDVDRAERGLVTVPLREWLGYAWVCLAD
                     EPPSFEDTVIGAAVERLGDTASLDRYRTEGLALGKRVTYDVRANWKLIIENFMECYHCA
                     TIHPELTDVLPEFADGFAAQYYVGHGAAFADEATGFTVDGTDGFGRLPGIEDTQDRRYY
                     AITVRPQVFVNLVPDHVIVHRMFPMAPDRTVVTCDWLYLPEIVDSGTDVSKSVELFHRV
                     NAQDFDACERTQPAMSSRAYRDGGVLVPSEHHIGAFHQWVTDRLAGGSG"
     gene            complement(24468..25628)
                     /gene="solA"
                     /locus_tag="HEP86_RS05070"
                     /old_locus_tag="HEP86_05070"
     CDS             complement(24468..25628)
                     /EC_number="1.5.3.2"
                     /GO_function="GO:0050131 - N-methyl-L-amino-acid oxidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="solA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988347.1"
                     /locus_tag="HEP86_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05070"
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="WP_168477658.1"
                     /sec_met_domain="DAO (E-value: 1.1e-46, bitscore: 158.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPTYDVIVLGLGGMGSAAAHHLAARGARVLGLEKFGPVHNRGSS
                     HGGSRITRQSYFEDPAYVPLLLRSYELYEKLERDSGRDIATLCGGVMLGRPDSRTVRGS
                     LESARQWDLPHEMLEPREIRRRFPTLTPAADEVALYEERAGLVRPEYTVAAHVQLAGQD
                     GAELHFEEPVTRWEELPGGAGVRVHTPENTYTAGQLVICPGAWAPQLLTDLGVPFTIER
                     QVMYWFAPDGGTAPFVPDQHPIYIWEDAQGVQIYGFPSIDGPDGGAKVAFFRKGTVCTP
                     ETIERTVHDHEVRAMAEQLAPRIPALPGRFLKAATCMYSNTPDEHFVITRHPAHPETVT
                     VACGFSGHGFKFVPVVGEIVADLALTGATAHPIELFDPRRPAAAAA"
     gene            complement(25693..28227)
                     /locus_tag="HEP86_RS05075"
                     /old_locus_tag="HEP86_05075"
     CDS             complement(25693..28227)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606613.1"
                     /locus_tag="HEP86_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05075"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_168477659.1"
                     /sec_met_domain="DAO (E-value: 5e-52, bitscore: 176.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTPAPSSRVVVIGAGIVGCSLADELTARGWTDVTVLEQGPLPA
                     PGGSTSHAPGLVFQTGPSKTLTEFAAYTVQKFGSLDVDGLSCFHPVGGLEIATTEARWA
                     DLHRRAGLAASWGIRGELIGPQQCKRLWPMLDETTLYGGFHTPDDGLARAVLACRAQIA
                     RAEQRGARFLDRHTVTGIERADGRVTGVTTDRGTFPADHVVSAAGFWGPVIGAMAGVDV
                     PLLPLAHQYATTEPLPELAGVNDPRDEASKPILRFQDRDLYFREHTDRIGIGSYAHRPM
                     PVDPFTVAAFDDAPPSSQLRSSRGDPHVMPSSLPFTAADFAPSWQDSVGLLPALGASRV
                     AEGFNGVFSFTPDGMPVLGESRELRGFWLAEAVWVTHSAGVAKAVAEWMTDSRPAIDIH
                     ECDLYRFEDAQRSPAYIADRGAQNFIEVYDVIHPLQPMEQPRPLRTSPFYPRQQELGAY
                     FLEGGGWERPHWYEANAPLAEGLQLPERDAWSARYWSPIAAAEARATREKVALYDMTPL
                     RRLEVTGPGALAFLQRMTSNNLAKKPGAVTYTLLLDETGGIRSDLTVARLAPDRFQIGA
                     NSGADLDWLLRHAPDDGGPSRSSEAESGGVQVRDSTSGTCCVGVWGPLARALVQPLTRD
                     DFSHQAFGYFRAKQTYLGHVPVTAMRLSYVGELGWELYTTADMGLRLWDTLWEAGQEHG
                     VIAAGRSAFNSLRLEKGYRAWGHDMTTEHDPYEAGVGFAVRPAKGDFIGRAALEGRSEE
                     TASRRLTCLTLDDPAAVVLGKEPVLVDGTPAGYVTSAAYGYTLGRGIAYAWLPAAAAVP
                     GTAVHIEYFGEKIPATVAQEPLIDPQMERIRR"
     gene            complement(28278..29363)
                     /locus_tag="HEP86_RS05080"
                     /old_locus_tag="HEP86_05080"
     CDS             complement(28278..29363)
                     /EC_number="1.1.1.306"
                     /GO_function="GO:0050607 - mycothiol-dependent formaldehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0010127 - mycothiol-dependent
                     detoxification [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (24-282). E-value: 1.2e-11.
                     Score: 36.3. Matches aSDomain:
                     nrpspksdomains_HEP86_RS05080_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541027.1"
                     /locus_tag="HEP86_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05080"
                     /product="S-(hydroxymethyl)mycothiol dehydrogenase"
                     /protein_id="WP_168477660.1"
                     /sec_met_domain="ADH_N (E-value: 8.6e-28, bitscore: 95.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.7e-27, bitscore:
                     93.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHHVHAVVAAKQGAPVEPQMIVVPDPGPGEVLVAVQACGVCHTD
                     LHYREGAINDHFPFLLGHEAAGVIESVGPGVTDLAPGDYVVLAWRAPCGSCRSCRRGRP
                     WYCFDSRNATQPMTLLDGTPLAPALGIGAFAEKTLVAAGQAVKVDPHAGPEAAGLIGCG
                     VMAGYGAAVHTGGVGSGDTVAVIGCGGVGNAAIAGASIAGARRIIAVDIDDHKLDGATR
                     FGATHTVNSRGTDPIEAVRGLTGGHGADVVIDAVGRPETYRQGFYMRDLAGTLVQVGVP
                     DPDMRLELPLIDLFSRGGALKSSWYGDCLPSRDFPVLIDRYLSGRLDLDGFVTETIGLD
                     EVESAFDKMRDGRVLRSVVVL"
     aSDomain        complement(28518..29291)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS05080_PKS_ER.1"
                     /evalue="1.20E-11"
                     /label="HEP86_RS05080_PKS_ER.1"
                     /locus_tag="HEP86_RS05080"
                     /protein_end="282"
                     /protein_start="24"
                     /score="36.3"
                     /tool="antismash"
                     /translation="PDPGPGEVLVAVQACGVCHTDLHYREGAINDHFPFLLGHEAAGVI
                     ESVGPGVTDLAPGDYVVLAWRAPCGSCRSCRRGRPWYCFDSRNATQPMTLLDGTPLAPA
                     LGIGAFAEKTLVAAGQAVKVDPHAGPEAAGLIGCGVMAGYGAAVHTGGVGSGDTVAVIG
                     CGGVGNAAIAGASIAGARRIIAVDIDDHKLDGATRFGATHTVNSRGTDPIEAVRGLTGG
                     HGADVVIDAVGRPETYRQGFYMRDLAGTLVQVGVPD"
     CDS_motif       complement(28527..28559)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05080_0003"
                     /evalue="3.20E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="HEP86_RS05080"
                     /protein_end="279"
                     /protein_start="268"
                     /score="1.5"
                     /tool="antismash"
                     /translation="RDLAGTLVQVG"
     CDS_motif       complement(28884..28904)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05080_0002"
                     /evalue="7.30E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="HEP86_RS05080"
                     /protein_end="160"
                     /protein_start="153"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="PEAAGLI"
     CDS_motif       complement(29145..29183)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS05080_0001"
                     /evalue="5.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="HEP86_RS05080"
                     /protein_end="73"
                     /protein_start="60"
                     /score="9.7"
                     /tool="antismash"
                     /translation="LGHEAAGVIESVG"
     gene            complement(29553..30353)
                     /locus_tag="HEP86_RS05085"
                     /old_locus_tag="HEP86_05085"
     CDS             complement(29553..30353)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324990.1"
                     /locus_tag="HEP86_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05085"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_211117286.1"
                     /transl_table=11
                     /translation="MTDSVEGQAETKPPKQPGGVQSVDRAVTVLEILARHGEAAVTEVA
                     EELGVHKSTAFRLLAVLENRGLVGQEQERGKYYLAAGVLRLAGAAAVRLDISQEGAPVC
                     RELAAELGETVNIAVLEGDAAVNVTQARGPASVTAQNWLGRRTPLHATSSGKALLAYQP
                     RAVREAVLARKLPRLTERTVTSAAALRRELAEVVEQGFAVAIEELELGLRAVAAPVRAP
                     DGSVIGAISVSVPAYRLAEERLPEVVKATVSAAGELSRRMGYGS"
     gene            30522..30845
                     /locus_tag="HEP86_RS05090"
                     /old_locus_tag="HEP86_05090"
     CDS             30522..30845
                     /EC_number="1.14.12.19"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541025.1"
                     /locus_tag="HEP86_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05090"
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="WP_042152581.1"
                     /transl_table=11
                     /translation="MIPVCPLADLPTGESVRIDTAPPIAVFHADGQLYAIDDTCTHQDA
                     SLSDGWLEGCLVECPLHAASFDLRTGAATCLPARRAVRTHPVTVEDGMIYVHHHAAEEG
                     TAA"
     gene            30842..32023
                     /locus_tag="HEP86_RS05095"
                     /old_locus_tag="HEP86_05095"
     CDS             30842..32023
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988353.1"
                     /locus_tag="HEP86_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05095"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_168477661.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.5e-54, bitscore:
                     182.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSVAVIGASLAGLYAARALRAQGFEGRLVIVGEEHHRPYDRPPL
                     SKGFLTGATADQGQLALADAEEIAELDAEWLLGTRATGLDTQGRAVLLDGGRSLTTDGV
                     VIATGATPRRLPGPAPTGTHTLRTLEDAQALRAELTGGPVRVVVIGGGFIGAEVASSCA
                     ALGHDVTVVEAAPLPLVPQLGDAMAGICAALHADHGVTLLTGTGVARLHDGGAGGDGNR
                     VTAVELADGRLLPADVVVIGIGVRPHTAWLEGSGLPLDDGVCCDAGGVTPQPHIVAVGD
                     VARADGTRAEHWTSATEQAAVAVRNLLAGRTVATHRSLPYFWSDQYGVRIQFAGRRLPT
                     DTPRIIEGSPDDRSFLACYERDGHTTAVLALNRPRPFMRLRRELARAAQPVTT"
     misc_feature    complement(32242..32257)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            32253..33374
                     /locus_tag="HEP86_RS05100"
                     /old_locus_tag="HEP86_05100"
     CDS             32253..33374
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825694.1"
                     /locus_tag="HEP86_RS05100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05100"
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="WP_168477662.1"
                     /transl_table=11
                     /translation="MTASAAATRAAQTLSRPFTLGGRTVPNRIAMAPMTREFSPGGVPG
                     ADVADYYARRAAGGVGLIITEGTYVRHPAAGTSDAVPRFYGADALDGWSRVVEAVHAAG
                     GTIMPQLWHVGMARKAGAPPFPDAPPSGPSGLALDGTPSGHAMTQQDLDEVIAAFAEAA
                     ATAERLGFDGVELHGAHGYLIDQFLWSGTNRRTDAYGGSRTARTRFAAEIVAACRAAVS
                     PDFPILFRMSQWKMGNYEARLAETPDELQEIVAPLTDAGVTAFHASTRRYWLPEYEGSD
                     LNLAGWVKKLSGRPTLTVGSVGLDNEFLATFAHEQAGVSGIDRLLDRLERDEFDLVAIG
                     RALLGDPEWAAKILAGRTDALVPFDASMLRTLN"
     gene            complement(33452..34306)
                     /locus_tag="HEP86_RS05105"
                     /old_locus_tag="HEP86_05105"
     CDS             complement(33452..34306)
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540994.1"
                     /locus_tag="HEP86_RS05105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05105"
                     /product="tetrahydrofolate dehydrogenase/cyclohydrolase
                     catalytic domain-containing protein"
                     /protein_id="WP_168477664.1"
                     /transl_table=11
                     /translation="MSPEARLMDGSALARGLVEQAARRAADLTERTGTAPCLATVLVGD
                     DPASVTYVRMKRNRCAKAGILSRHVALPAATTTVELVDTITALSNDPSVHGILLQHPAG
                     PHIDERAAFEAIAPEKDVDGVTCHSFAAMSFGLDGFASCTPGGIIRLLDHYDVDLAGKH
                     AVVVGRSAILGKPVGMLLLGRNATVTYCHSRTTDLASLTKEADVLIAAVGRPRFLGAEH
                     IKPGAVVIDAGSNPGNVGDVDFDAARTRAALITPVPGGVGPMTIATLLTQTVDAAAAQL
                     NAG"
     regulatory      complement(34328..34416)
                     /bound_moiety="5-aminoimidazole-4-carboxamide
                     ribonucleotide (ZMP)/
                     5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl
                     5'-triphosphate (ZMT)"
                     /db_xref="RFAM:RF01750"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01750"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ZMP/ZTP riboswitches appear to regulate genes
                     involved in one-carbon metabolism; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(34362..34376)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            complement(34462..35394)
                     /locus_tag="HEP86_RS05110"
                     /old_locus_tag="HEP86_05110"
     CDS             complement(34462..35394)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS05110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_05110"
                     /product="hypothetical protein"
                     /protein_id="WP_168477666.1"
                     /transl_table=11
                     /translation="MEPRELWERHAVLAQAFCSSDDEVRRTQGLLDEAEARRSRTLAAF
                     AVTVGSDAVVADLLGLDEREVRLARRTVGKDDAREVAKNLLAQRPNEPAAAPQQPAPQA
                     PAAQAPTPQPAQGAAAPGPAAHATPPPPQPGQAAAPQPSEPAWAPALDAVLMSSWHSGV
                     DLTALATELGLDVRLLVARAQQLSADSRPMPPTPSDRTGRHRRLVNVPPPQPDPSSLTW
                     RERPQHPPREHYEQEPWKQQPYQHYPDQQQYQEYRVYEEHQQYQQPAQPIWDANAITAA
                     QHDWDGILSQWEATAAPQPPLSAPGQGGG"
     misc_feature    35506..35522
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.23"
                     /tool="antismash"
     misc_feature    35506..35524
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.97"
                     /tool="antismash"
     gene            35557..35877
                     /locus_tag="HEP86_RS05115"
                     /old_locus_tag="HEP86_05115"
     CDS             35557..35877
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606606.1"
                     /locus_tag="HEP86_RS05115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_05115"
                     /product="hypothetical protein"
                     /protein_id="WP_168477668.1"
                     /transl_table=11
                     /translation="MSVPSSGTVAGHGPTSLPRPGQMPRWITAKVIRQTPVFAGLVKQW
                     TERAATVPGVADPEWQRLVSYRALMEETEIALTALRPHRAPDVLPPRKPTVPAARPARL
                     DA"
ORIGIN
        1 ccgcggcggc acaggcgagc ggcgagcacc cggacaccgc actccccact cagcgcaccg
       61 gcgacacccc cggcacagac aacccccacg gcaccgaaag caccgagaac tgatcatgag
      121 tcagcgcacc accctgccgc cgcaccgcac cgcgggcgcc ccgcccgcgg tccgcgaacc
      181 ggcccatgtc cccgtcgccg atgtgatgcg cgcaggcatc gtcgagggcg tccaccacgg
      241 ctccgtcgtg gtgctggcgg ccgacgggag cgtggcattc caggcgggcg acatcgaggc
      301 ggcgttctac ccgcgctcgg cactcaagcc cgtccaggcg gtcggcctgc tgcgcgcggg
      361 cctgccgccg ctggacgatc cgtcgctggc cctggtcgcg gccagccact ccggcgagga
      421 gcagcatctg gccacggccc ggggcatcct ggccgccggc gacctgaccg aggacgagct
      481 gcgcaacgtc cccgatctgc cgtacgaccc cgccgtacgg gacgagtgga tccggcgcgg
      541 tctggggccc acccggctcg cgcagaactg ctcgggcaag cacgccgcga tgctgctgac
      601 ctgccgcacc cggggctggg atctggacgg ctacctcgat cccggccacc cgttgcagcg
      661 ggaactcgcc gcggcggtcg aagacctcac cggccagggc atcgcccggg tcacggtcga
      721 cggctgcggc gccccgctgt tctccgtctc cctccacggg ctgacccggg ccgccgcccg
      781 gctggcgacc gccgcccctg gcaccgggga gggccgggtc gcgcacgcca tgcgcacgca
      841 cccggagatg gtgtccggca gccggcggga cgtcgcccgg ctggtgcggg cggtgcccgg
      901 tctgctcgcc aaggacggct tcgagggcgt gcagatcgcg gccctgccgg acggccgggc
      961 ggtcggtgtg aagatcgccg acggcggtga ccgcgcccgg atgccggtga cggcggcggc
     1021 cctggcgcac tgcggcgtcg accccgacgc cctggccccg ttcgccacca cacccgtcat
     1081 cgggggcggc acccccgtcg gatccttgcg ggcaacgaaa gcccttgccc cgtaagccat
     1141 ttgacgcccc atcacctccc tgccaggcac acccgcccgg actcctcccc ctccgctcca
     1201 cctcacaaag gacccgctgc accatgactt ccgccggcca ccgccgcgaa cacgatctgc
     1261 tcggcgaccg ggagataccc gccgaggcgt actggggcgt gcacaccctg cgcgccgtgg
     1321 agaacttccc catcaccggt acgccgatcg ccacctaccc gcacctgatc aacgcgctcg
     1381 ccgccgtcaa ggaggccgcg gcccgggcca accaggacct cggactgctc gacaccgagc
     1441 gggccgacgc gatcgccgcc gcctgccggg agatccggtc cggcgggcag ctgcacgacc
     1501 agttcgtcgt cgatgtcatc cagggcggtg ccgggacctc gacgaacatg aacgccaacg
     1561 aggtgatcgc caaccgggcg ctggagatcc tgggccatga caagggcgac taccgccatc
     1621 tgcaccccaa cgagcacgtc aatctgagcc agtcgacgaa cgacgtgtac ccgacggcgg
     1681 tcaacgtcgc cacgatcatc gccgtacggg aactgctcga ctcgatggcc gtcctgcgcg
     1741 aggcgttcgc ggccaaggcc gaggagttcc gcgacatcct caagatgggg cgtacccagc
     1801 tccaggacgc ggtgccgatg accctgggcc aggagttctc ggcgtacgcg gtgatgctgg
     1861 aggaggacca gagccggctg gcggaggcgg tcctgctcat ccacgagatc aacctcggtg
     1921 ccaccgccat cggcaccggc ctcaacgccc ccaagggcta cgccgaggcg gcccgtaccc
     1981 atctggccgc cctcaccggg ctgccgctgg tcaccgccgc caacctcgtc gaggccaccc
     2041 aggactgcgg cgcgttcgtc catctgtcgg gcgtcctgaa gcgcatcgcc gtcaagctct
     2101 cgaagagctg caacgatctg cggctgctgt cctccggccc gcgcgccggg ctcgcggaga
     2161 tcaatctgcc gccggtgcag gccggttcga gcatcatgcc cggcaaggtc aacccggtta
     2221 tccccgaggt cgtcaaccag gtcgccttcg aggtcatcgg caacgacgtc accatcacca
     2281 tggcggccga ggcgggccag ctccagctca acgccttcga gccggtcatc ctgcactccc
     2341 tctcggagag catcacccac ctcggggcgg cctgccgcac cctcgccgag cgctgcgtgg
     2401 cgggcatcac cgccaacacc gagacgctcc tggccagtgt gcagaactcc atcggcctgg
     2461 tcaccgccct caacccgcac atcggctaca ccgccgccac cgcgatcgcc aaggaggcgc
     2521 tggccaccgg acgcggcgtc gccgaactcg tcctggaaca gggcctgctc ccggccgacc
     2581 ggctcgccgc gctgctgcgc ccggaggaaa tcgccggtac gggcggtgac ttgagcacgg
     2641 tctgacaccg gcccgcccgg agcacgtcag ccgaacggtt ccggggccgg gaccacgtca
     2701 cacaggatct cgaccggtga ccgaccgtga gcaggtcacc cgccgtgccg tccaggaggg
     2761 ggccggaatc gccgtggccc cctcctggac gtgctcccgg ggcgggttcc ggcgcacgat
     2821 gaggaggagt gcacctgtct gacgaccggc tccgggcagt cggcaggcag gatggtcacc
     2881 ggcgctcccg gccgggtgag acgggccggg cgccggaacc aggtcctgaa gacaccgcac
     2941 gagagagaag agatccgcat gcgtatcgcg ctgtgccaga tgacggcaac gaccgatccg
     3001 aaggagaacc tcgcgatcgt ccaggaccag gtccgccgtg cggcacgcga gggggcccgg
     3061 ctggcggtcc ttccggaggc ggccatggtg cggttcgggg cggcgctcgg gcaggtggcc
     3121 gagccgctgg acggtccgtg ggcggagggc gtgcgggcgg tggcccggga gaccggcgtg
     3181 accgtggtgg ccggcatgtt caccccggcg gacgacgggc gggtgaccaa caccctgctg
     3241 gccaccggac ccggcgtcga ggagttctac gacaagatcc atctgtatga cgccttcggg
     3301 ttccgggagt ccgaagcggt cgcccccggt aagcgcgtgg tgaccatcga tgtcgacggg
     3361 gtccgggtgg gcctggcgac ctgctacgac ctgcggttcc ccgaactctt ccgggcccac
     3421 gccgacgcgg gggccacggt gtcggtgctg cccgccgcct gggccgcggg gcccggcaag
     3481 cgcgcacagt gggacctgct ggtgcgggcg cgcgcgctgg acgcgacggt ctggctggcg
     3541 gcggtcaacc aggccgcccc ggatccgcag gccgacccgg aggcccccac caaggcgccg
     3601 accggtgtcg ggcacagcgc gctgatcggc cccgacggga ccgtacgcgg acagctgggc
     3661 gaccgccctg acctgctcgt cggggacgtg gacaccgagg agaccgcccg ggtgcggcgg
     3721 gcggtggcgg tgctggacaa ccggagcatg taggcgggcc ctcagccgtg cacgtccacc
     3781 gtccctgacg gggcgtcaac ccgggggcat accgcggccg ctcagcggtc ggtgcggatc
     3841 accaccgcca gcgtgcgcgg accatgcacc ccctcgaccc gctccagctc gatgtcggag
     3901 gtggccgagg ggccgctgat cagcgtgatc ggatgctccg gcgtcaactg cgccaccgcc
     3961 tccggcactc cggtccgcac cgacgacagc tcgacgacac agacgtgcag atcgggcacg
     4021 agggtcagtg cgcgcctccc ctgatccgcg gcggcgccgt ccaggaagat ggtgccggtc
     4081 tcggcgcagc tgacggcgga gccagtcacc accccgtcca gcgcatcgag cgagggcgcc
     4141 ggcacgtcgg cggaatccgt caccgtctcc ccgtcatacc cggccagcca ggccggatcg
     4201 agcccctgag gtaggccgat cttccgcgcg ccgtgcgcat gcagcacctc ggcgagcacc
     4261 gtcgccgtgg ttgcggcggt gcaggtgcgg acctgcgccc ggtagtcgac gagccggtcg
     4321 gcgaagaggg cgagccgctc ctcgtcgggg agcgagcggc cggtgcgata gccgcggggg
     4381 acggtcactt cgggcccgtc ggagagggcc agggcgtccc ggacacggcc gagcaccgtc
     4441 tcccgtgcgg tcgcggtcac gattcctcct gcggggcgtc gtcggtgtgc ggggcgtcgt
     4501 cggtgtgccg ggcgccttct tcggccgcgg cccgcatcgc ggccgcgccc tcggcggagg
     4561 cgaaccagga tcggaaggtc tgccggggcg gggcgggggt gtcccggctg tcgctccagc
     4621 cgttgagcgg cgggggcaga cgggagaggg tgccgtcccg ccccgccggt acgcgtccga
     4681 gaccggccgc cttctgtgcg gcggtgaaca gcccgggccg cttcatgacc gcggccgcgg
     4741 ccttcatcgc cagcttctcc gcggtcgtcc cggactgttc ggtgtgctgg tggcgcagct
     4801 cgacgaggag cgacggaatg tcgatcttca ccgggcaggc gtcgaagcag gctccgcaca
     4861 ggctggaggc gtacggcagt gagctgttgg gatcgccctt ggcgccatgc ataccggcca
     4921 gctgcggggt gagcaccgca ccgatcgggc cggggtacgt cgatccgtag gcatggccgc
     4981 cggtccgctc gtagaccggg cagacgttga ggcaggccga gcagcggatg cagtggagcg
     5041 ccgcgcgccc gatccggtcc gcgagcgccg ccgtccgccc gttgtcgagc agtacgagat
     5101 ggaactcctg cgggccgtcg cccggtgtca cgcccgtcca cagcgaggtg taggggttca
     5161 tccgctcacc ggtcgaggag cgcgggagca actggaggaa gacctccagg tcctggaagc
     5221 ggggcaggac cttctcgatg cccatgacgg tgatcagcgt ctcggggagc gtcagacaca
     5281 tccggccgtt gccctcggac tcgaccaccg ccagggtgcc ggtctcggcg atgccgaagt
     5341 tggcgccgga gacggccact tgggtcgtca tgaacttctc gcgcaggaag gcgcgcgccg
     5401 cggcggcgag ccgggcgggg tcggcgttca gcgcggggtc gacgcccggg aggtgccgga
     5461 ggaagatctc ccggatctcc tcgcggttgc ggtggatcgc gggcaccagg atgtgtgacg
     5521 gccggtcgtc ggcgagctgc acgatcagct cggccaagtc ggtttccagc gccgcgattc
     5581 cctgagtcgc cagatgctcg ttgaggccga tctcctgcgt ggccatcgac ttgaccttga
     5641 ggatctcgtc gctgccggta tcccgcacca gccgggtgac gatctcgttc gcctcgacgc
     5701 cgtcccgggc ccagtggacg gtgccgccgc gctcggtgac cttccgctcc agttgctcca
     5761 gcagttcggg cagccggttc atggtgtcgg tcttgatcgc cgagccggtg tcgcgcagct
     5821 gctcccagtc gggcagttcg ccggtgacgg cgaggcgctt ggcgcggatg gagtgggtgg
     5881 ccttgcccag gttgcggcgc agttgcccgt tgcccagctc gtcatgcgcg gcccggggga
     5941 agctgcgctc accgcgcaga tggcccgtcc cgtacgggga gcgcgggggg acggcgggca
     6001 tgccgaggaa ggtgccctgc gtcgcggggc cgttcggact gctcatcggg cggcctccgt
     6061 caggacgtgc ggcgcggtgc gggtggcagc gaggatctgg gccagatgca gggtccgtgt
     6121 gccggacctg atgcgtgaga gaccaccgcc gatatgcatc agacaggagg agtcgcccgc
     6181 cgtgcacacc gcggcgccgg tgccggtgat gtggtccatc ttgtcccgca gcatcgcggt
     6241 ggaggtctcg gcgttcttca ccgcgaaggt gccgccgaag ccgcagcagg cgtcggcctc
     6301 gggcagctcc accaggtcga tgccctcgac ggcgcgcagc agccgcagcg gcttctcgcc
     6361 gacccgcagc atccgcagcg agtgacaggt ggggtgatag gtcacccggt gcgggaagta
     6421 cgcgccgacg tcggtcagat cgaggacgtc gacgaggaac tcggacagct cgtacgtctt
     6481 ggtccgtacg gcggccacac cggcgcggag ggccgcgtca ccgtagcgtg cggcgacgat
     6541 ctcgtgctga tgacggaccg agcccgcgca ggagcccgac ggcacgacca cggcctcgat
     6601 cgccgggtcg ccgaactgtt cggcgaagtt ccgcaccagc ggcaccggtt cacgctgata
     6661 gccggtgttg acatgcatct ggccgcagca ggtctgctgc ggtgggaaga ccacgtcatg
     6721 gcccagacgg gccaggagta ccgcggtgga tttcaccgcc tccgggaaga gcgtgtctcc
     6781 cagacaggtg gcgaagaggg cgatgcgcat agagcctccc tggcgcttat ggtccgacca
     6841 tactcccctc gaaccgagtg agaaaagtaa ggacgcagtt tggtccgacc ttattgacat
     6901 gcgacatctt cggtgggcta ctgagggccg ttcgtcagcc acacggcgcc gcgatggccg
     6961 gaacgggacg ttcaccaccg gccggacggc gcgcagaact cgatgaggag cactccgtgg
     7021 ccaccactcc gcccgctgcc ctggcggcct acacccccga cgtggccgcc gtcggggaca
     7081 gcctcaccac caccgcgcta ctgggcctgg tgcccctggc gaccttcttc ctgctgctga
     7141 tggcggccag gcgctccgcg ctgcactccg ccctcggcgc cctgctgacc gcactcctgg
     7201 tcgcggtcct cggctacggc atgccgctgc ggctcggcgc gctgtccgcc acgcagggcg
     7261 cggccttcgg cctcttcccg gtgatgctga tcgtcgtgtc ggccatctgg ttctacgaac
     7321 tcaccgtggt cagccaccgt ttcgacgatc tgcgccgctc cttcaacgcc gtcggccgcg
     7381 gcgatctgcg catccaggcc atgctcatca cgttctgttt cggcggactg ctcgaagcgc
     7441 tggccggctt cggcgcgccc gtcgcgatca ccgccgccat gctgatggca gtcggactgc
     7501 cccggctcac ctcggccgtc accgtcctgg tcgccaacac cgcgccggtc gccttcggcg
     7561 ccatggccat ccccatcacc accgcgggca acctcaccgg catccccgcg gagtccctcg
     7621 ccgccgtcat cggccggcag agcccgctgc tcgccctctt cgtgccgcag ctgctgctct
     7681 tcctcgtcga cggatggcgc ggtctgcggc agttgtggcc catcgccctg gccaccggcg
     7741 ccgtcttcgc cctggcccag ttctggtgct cggcccactt cgcctacgaa ctcaccgatg
     7801 tcgtcgccgc gctcgccggc ttcggcgccg cggtggtcat gctgcgcttc tggaccccca
     7861 cgacaccgga cgaccagcgc tcccaggtca cggccgaacc gctgacccgc cgccgcacct
     7921 tcctggccgt actgccctac ctcctggtca tcgcggtctt cgcgctcgcc aagctcgaca
     7981 tcggcggact cgacataccc gggctgctcg gctccctcac cgtccagctc gactggcccg
     8041 gcctctacgg caacctcctc gcccccgacg gctcgcccgc cggcagcgcc gtctacaaac
     8101 tggaggtcct ggccaatccc ggcaccctgc tgctgctctc cgggctcctg gtgatgctga
     8161 tctacagccg cgcgaaggac gccgaccgct tcccgatgac cgcccgctcg ggactgtcct
     8221 gcgccgggcg caccctgcgg aacatgcgca ccgccatcgc cacggtcgcc accgtgatgg
     8281 cactgagcta cgtcatgaac cagtcggggc agaccctcgc catcggcacc tggctcgccg
     8341 ccgcgggcgg gctcttcgcg ctgctctccc ccgtcctcgg ctggctcggc accgcggtga
     8401 ccggctcgga cacctcatcg aacgccctgt tcgccaccct tcagcagacc gccgggaaga
     8461 ccgcgggcat cgacccgacc ctgctggtgg ccgccaacac cacgggcggc gtggtcggca
     8521 agctgatcag cccgcagaac ctgaccatcg cggcgaccgc ggtggaacag cccggcaccg
     8581 agcggatcct gctgcgcaag gtcgccggct acagcgtcgc gatgctggcg gtgctgtgcg
     8641 tactggtcta tctccagtca ctgccggtgc tgtcctggat gctgccgtag acatacgggc
     8701 gggggagggc ggggacagcc cttagcttgt cttttaaccc cggaatcgga cgttgatgct
     8761 gccccgtggt ctacctgggc tgctgggtga tgttgaccat ccaggtgatc ccaaactggt
     8821 cgacgagcga gccagcctcg tcaccccatg actgcttctc caggggcagc gtcaccgtgc
     8881 cgccggcgga cagcctctcg aagtagtcgc ggagtttggc gtcgtcgccg tcgaggaaga
     8941 ccgcgacgtt gttgcccggg gtgtggggca tctcttcccg aacgtcccac gccatcagcg
     9001 tgtagccgtc tggggtgcgg agcgtggcgt gcatgatctt gtcggggtga ggcacgtccg
     9061 gcgagccgta ttcggcgtag gtgcccatat ccagctggcc gccgaggacg tcctgataga
     9121 actcgatcgc ctgccgtgcg ttcccgttga aggcgaggca cgggttgagt tgagatccca
     9181 tctgatgctc cttggcgtga gtgattcgaa cggcttgaac gtagcaacgg gcactgacaa
     9241 ccgtccgagc ctggcagcac gcaggtcagc tgacatcggg gctccaagat gcccggcagg
     9301 gtcgctcagc ttgctatttg atctttgcgg cctttgaggc gattgcgttc ggtgatggtc
     9361 tcgggtcgcc tggtcgtttt gcccacgtcg tgacgggtgg ggggatgacg gttcttcgac
     9421 ccgactggcc tgcctggtcc gggggttgag ggtttcggtg cacgggctgg gcagtgcagg
     9481 tgcgggcgga ggttccgaaa cccgcggcgg accctggcgg gggtgaggcg tgctggctcg
     9541 gtcggcttct cccaggggcg gcggagatca gcagcggcct cgcgggtgag ccgcagttgc
     9601 gtgtgggccg cgatcacgag ccacgtccag tgatccgcgg cctcgggggt gcggagcttc
     9661 gggcgggccc agccgagcgt ctgcttgatc attctgaagg tgtgctcaag atcgaatctg
     9721 cggaggaacg cctgccagcg caggtcgact tcctcgctgg tcataccggt cttcgaggac
     9781 cacagccaga ggggcagcgg gtcctgaccc cgggcaggtg gtcgacctgg aggcggatca
     9841 acgtgccttc gaggagcggg agttcaccct cgtggtcgat ccacgcagag cgggtcgtga
     9901 gccgggggtg gattcggtcc caggctatgg cctgggcggt gccgtaccgg tcggtgacct
     9961 gcatcgtcgc ggcgtctggc tctccccagg tctcgggctt ggcgaagcgg aactcgttgc
    10021 cgtgcctggg gtagcggcca ccgtaggggt tggccagggc gaactctttt cgcgagggcg
    10081 ccggacggcg catcacccgg tccgcacgca ttcgccccag cacctcgatg ggcaggccgt
    10141 cgagcaggta ggccatgcgc ggggcgtcgt atccggcatc gaagacgacc aggatgtccg
    10201 cgtctccggg ctcccactgg ccgccgtcga tcaggtcggt gaccacgcgg cggacctggg
    10261 cagcggtgac ctcggcgaca tcgtcgtcgg gacccaggcg gaccgcgtcc agcagctggc
    10321 accaggaagt gcggcccgtc tccagggcgg cgacgaacga gtacggccag ccgggaatga
    10381 actggtcgct ggagcgtccg ttgcggccat aaacgtggca gaacagtcgg tccgggctgc
    10441 acggggcgtc gggacgcagc cagttggtca cgtcgaccgc gagggcgagc cggttgtcgg
    10501 cggccttggg ctgcgggagc acagccagag tgcggcgaag cctgtccgcg gcgatgcggc
    10561 cgcagttcag cgcgtcgtac aacgcgccgt gcccacggcg gtgctcggcc agcagtgtca
    10621 ggtccacggg cgaggtcacc ggcccgttct cgcagagcat cgcgtcacac agctcgaaca
    10681 gggtgtcacc gcgccgagtc aggcacgcgt agaagtcctc ccggaagtgt gacgtgaagt
    10741 cgaacgcgtc ccgccgggca tcgtggttca gcaaactcac ctctgcggcc ttcgtatgaa
    10801 tctgattccg tggcggaatg caggatcatg cgaaggccgt ccgcctgtcc ggcgaatccc
    10861 aaggtgagtg acgtcgtacg acaccccgtt cgaggccaga ggttaaaaga caagcttagg
    10921 gtctgttgcg aaagtggatc ttggtcgtgg atgatcacgc cctgtgggac gtggtgatct
    10981 gacgaacggc cagtgggccc ggccggagcc gttgttgcca cagggcatca agccgggccg
    11041 tccgccggtg tggagtgggc ggtcagcctc ctgcggctcg gcgacaccac ggtgtcggcg
    11101 gtcgcgcggc ggctcggggt gaaccggcac acctgctgga aacgcggtca agaagcacgc
    11161 cgagacctcg atcgaccggg gtgcgtcagc gggtagtgag caccatacgg aaacgcacgg
    11221 cgccggagag catcttctga tacgcctcat cggcctggtc cagcggcatg atctccgtca
    11281 tcgggcggat cccgtggagg gtgctgaacg ccatggtgtc gtgcacatcc tgcgcggtgc
    11341 cagacgggtg gccgcgtacg atccggcctt gcaagatcag ctggactggg ctgatgccca
    11401 tcggctcgaa ggccgcaccg atgaccacca gctcgccgcg gtgggacaac ccgtcaacgg
    11461 tcgccgtgat cgcgtcggag ctgccggcgg tggccagcac gaccttcgcg ccgccaaggg
    11521 accgcagcgc gtctgcgacg gtggtgtccg ccgtgctgtc gatgtagtgg tgcgcgccga
    11581 gttgcttggc gaggtcggcc ttggcagttc cacgggcgat ggcgacggtc tcgaatccca
    11641 tcgcggcggc atactgcacc cccaggtgac cgaggccgcc gaggccgagt acagcgacca
    11701 ggtcacccgg ccgtccagag ctgcgccgca gcccgttgta cgtggtcaca ccggcgcagg
    11761 ccaaaggccc ggcatccgtg gacgccagcg catcgggggt ccgggccagg gcatccatcg
    11821 gggcgatcat cgtctcggcg aaaccgccgt cgtaggccca tcccgggacc ttcaggttct
    11881 cgcagacgat gaagtcgccc tgtcggcagg gcgtgcagtg gccgcagctg ccgccgaacc
    11941 agcccaccgt cacccgctca ccagcatgcc agccgcggct ttgggccccc tcgccgagct
    12001 cgtcgattcg cccggcgatc tcatgcccgg gaaccagcgg aaaccgtacg cccggaaagg
    12061 cggcgtcgac gaaggcggcg tcgctatgac agatcccgca ggcgtccacg gccacccgaa
    12121 cgtgacccgg gcccggctcc ggtacctcac gctcaacgat ctcgaaggtc ccgccggggg
    12181 cggcgacctg cgcgactcga tgtgtactca tctggatctc tcctgaatcg ggcacgacag
    12241 ccctgtaatc cagcagacca gctccagccc gatcgcgcgc gccgaagggg aagcggcgac
    12301 gggcgagctg cgccctgtag gcgcgtcttt cgcatccgca tcggactgca gctgctcgcg
    12361 gatgtgatgc caggtgccgt cacgctgccc taccttcttg ggtgcgtccc agtaggtcgc
    12421 gaccctggga ctgcgcgggt ggggcaggga tggttctcat gctggctgcc gtccatggct
    12481 cgggtggctg acccccagcc ccgccacttc ttccccttgg gcagcaacgg ttccaaccgg
    12541 acccactgag cgtctgtcag atctccacgc gccacaccgt gatcatcgcc gatcaagatc
    12601 cactttcgca acagacccta agggctgtcc gcgcccgccc ggccctcgtc ctcttgctcc
    12661 tgctcctgct ccgccggggc gttctcgtcg accagtcggc cgtggaagcc gcggatatgt
    12721 gtctcggcca gatcggcggc cttcgcgccc ttgccggccc gtaccagtcg cagcagctcg
    12781 gtgtgctcgg cgttcagcgc cgccgccgtg gccggccagt cctccgccgt ctccagcgcc
    12841 cgcaggatca gcggacgcac cgactcccgc acggccgagg tgagggtgga ggtcagctga
    12901 ttgcccgagc tgcgcgcgat ggcgacatgg aaccgggtgt ccaggtcgtt gaagtcggcg
    12961 gcccccacgc cgggctcgcg catccggtcc aggagcgctt ccgcctcgtc gaggtcccgc
    13021 gccgaggcgt gctccgcggc cgcctcgaag ctggagcgct ccaggaccac ccgggcctcc
    13081 agcacatcgt gcagccggta gctgcccagg gcgaagtgca ggcgcagcag ccggcccagc
    13141 gcatcgtccg ggttgcggac gatccgcgcc ccggcgtccg gcccgcgccc gggctgggcg
    13201 accagcaccc cgatcgtctc cagcacccgc agcgcctcgc gcagcgcgga ccggctgacg
    13261 cccaggaccg gcgccagctc gcgctcgggc ggcagacgat ctccggcctt gagttcaccg
    13321 gcgagcaccc gctcctcgat gcgctccagc acgagctcat gcgtgcgcga ctgccgcaca
    13381 ggtcgccatt cggcggtcat ccccaactcc ccggctcggc cctcatgctc ccgtgcaaaa
    13441 actatgtcac acaggacgtg tggtcggacc acactgccgg acgccgcgga gggctcggcc
    13501 gcgggccttg cgtacggccg tcgcggcagg tcagaccgcc aggtcagacc tccaggtcca
    13561 gccgcggccc gtcgcgccgg gtcggctcgc ggcggagcag ctgctcctgg gcggtggtcg
    13621 cgatccggtc gaggacccgg cggcgcagtg cgtcgggcgg ggtgaccgct tccgcgtcgg
    13681 ccagacacgc gacggtggcc tccaggtcgg cgacctcccg ggtgcaggcg tcgcagctcg
    13741 ccaggtgggt ggcgaaggcg gccgcctcct cgggcggcag ggcgtgcagg acgtacgccc
    13801 cgaccgcctc gtgcggatcc tcggcagcag acatcagtcg cctcccatac agacgcgcag
    13861 tctccgcagg ccggtgcgca tcctcgtctt gaccgtgccc gcgggggtgg acagggcctc
    13921 ggcgacctcc gcgtaggtca gtccctggta gtaggcgagg accagcggca ggcgctggga
    13981 gttgccgagg ccggccagac agcggtagac ctgcgcccgt tcctcccgct cctcgacggc
    14041 ctccaccact tcgtcgaacg gggtctggtg ggccagctgc gcggccttcc gctcgcgttc
    14101 cgcgccggcc cgcaccgatc gcacccgttc caccgctcgc cggtgggcca gcgtcagaac
    14161 ccaggacttc gcggcaccgc gctcgggacg gaaccggtcg gccttccgcc acacctcgat
    14221 catcacgtcc tgagtcacct cttcagcctg cgcctcatcg cgcaggatcc ggtaggccag
    14281 gcccatgacg ggcaccacga gggcgtcgta cacgccgacg aacgccggct cgtcgcccag
    14341 ggcgacgcgc acgagcagct cgtccacgag acggtccgcg gcagaccgct cgggagggcg
    14401 gggcccctcg ggtgcggtgt gcgaaatgcg cctcacgacg tatcgaccgt cccctcgtcc
    14461 gtccggtgcg gcccgggtcc ccgggatgga gcgcgccggg acgcgttgcc acgtctcggc
    14521 cgcgccctcc caggctgacg ttccctcacg cggaccgcag ccggtcgggg cccgttcgac
    14581 tgagggggag ccctggcccg cgcaccctgt gctcggcgcg tggtcgtgtg cgggacgcgg
    14641 acgacgcccg tgcacgaggc cggtaagggg cccgcagtgg ccggtcatcc gcgcagaagc
    14701 agcaggtcac cccggctgcg gaggtcttac gtaagggaat agggagacct ccgcaggaga
    14761 aaaagcgcat ttggtgcaat ccacgcccgt acgggcctcg aatacacatt aggaactgcc
    14821 cgtgcgacgc ctatcgagcg cctgcgggac ccggtgacgg gacgacggtc gtcggcgctt
    14881 gtcagggagg tcgccatggt cggagagccg gtcgaagaac tgacctcgta tccggaggaa
    14941 tccccggccg gacagtgcgg cgcggacggt ccggcccccg gtgtcgaggc cgccttcgcc
    15001 atgacactgg ccgaggtcat gggtaccggg cagacgccgg tggaccggca tttcttcgac
    15061 gatctgggcg ccgactcctt ggtgatggca catttctgtg cgcgggtcag gaagcgtgcc
    15121 gacctgccgc cggtgtcgat gaaggacatc taccggtatc cgacgatccg ggcgctggcc
    15181 acggcgttgg cgggctcccc accctctctc ccggtcgaga ccccgccccc ggcaccgact
    15241 cccccgtcgg cgccggctcc cgctgtcagg ggcacctcgc ggtacgtgct gtgcggagcg
    15301 ctgcaactgc tgatgttcct cggctacacc tctctcgtcg cggtggccac ggcctggggc
    15361 tatgagtgga tcgccgccgg gtccggcgtg ttcggcagat atctgcgttc ggtgctgtgc
    15421 ggcgcggccg gtctgctgtt gttgtgcgcg tttccgatcc tggtgaagtg ggtcctcatc
    15481 ggccggtgga agccccggca gttccgcgtc tggagcctgc cgtacgtccg cttctgggtc
    15541 gtcaagacgc tgattcgcgc gaacccgctg gtgctgttcg tcggttcgcc gctctacacg
    15601 ctctatctcc gggccctggg cgcgaggatc gggcgcggcg tagcggtctt ctcgcgcaat
    15661 gtgccggtgt gcaccgatct gctggccctc ggcgacggca ccgtcgtccg caaggacgcg
    15721 ttcctcaact gctaccgggc tcaggccggt gtggtgcaga ccggcgcggt ggtcctcggg
    15781 aagaacgtgg tcatcagcga ggccacggtg ctcgacatcg agacggcgct gggtgacggg
    15841 gcgcagctcg gccatgcctc gtcgctgcac agcgggcagg tggtgccgga cggcgaacac
    15901 tggcacggat caccggcaca gcggaccgat gtggactacc gcgtggtgaa accggcccgt
    15961 tgcggtgccg tgcgcaggac ggtgcacagc gcagtccagt tggtgaccgt gctgctgctg
    16021 tacgtgccgc tggcggtcgg cggggtgagc atcctgctgg ccgaggcgcc gcagctcagt
    16081 gcggtcctgg aacccggccc cacggcgctg gccgacgggt cgttctacgt ggacgccctg
    16141 ctggtgtcct tgctcttctt cgccgccgtg ccgctcgggc tgctcttcca ggccacggtc
    16201 ccgcggctgc tcagccggac cctcaccccg ggcaaggtct atccgctgta cggcttccac
    16261 tacggggtgc agcggctgat cgccctcacc accaaccgga agttcctgat gcgactgttc
    16321 ggcgacagct ccgccatcgt ccactacctg cggggcctcg gctacgacct ctcccggatc
    16381 gaacagaccg ggtcgaactt cggtaccgag gtcaagcacg agacgccgta cctgagttcc
    16441 gtcggcagcg ggacgatggt cgccgacggt ctgtccgtca tgaacgccga cttctcggac
    16501 acgtccttcc gcgtctgccg gacctcgatc ggaccgcgca acttcctcgg caaccggatc
    16561 gcctacccct cgcggggaaa gacgggcgac aactgcctgc tcgcgacgaa ggtcatggtc
    16621 ccggtcgacg gcgaggtccg ggagggcgtc gggctcctcg gctcgcccag cttcgagatt
    16681 ccccgctcgg tccagcggga cagcaccttc gaccagctga agaacggcga gcagctgcgc
    16741 cgccacctcg ccgccaagaa ccggcacaac gccgccacca tggggctcta cctcctggtg
    16801 cggtggctct acttcttctg ggccaccctg ctcgtggcgg tcgccgcgga gctctatgac
    16861 tccgtcggcg ccttggcgat cgcgctgggc aacgtcctgg tgctggtgtc cggtgtcgtc
    16921 tacttcgtgc tggtcgaacg ggcagtgacg gtgttccatc cgctgagccc gctgttctgc
    16981 tcgatctacg atccgcgttt ctggcggcgg gaacgcttct ggaaggtgcc ctcggagagc
    17041 tatctgctgc tcttcaacgg caccccgttc aagaacctga tctggcgtct gctgggggtc
    17101 cggatcggcc gcagggtttt cgacgacggc tgctatctga ccgagcggac cctggccgcc
    17161 atcggggacg gctgcaccct caacgtgggg agtgtcgtcc agtgccactc gcaggaggac
    17221 ggcaccttca agtccgaccg cagcacgctc ggcgcgggct gcacgctcgg cgtcggtgcc
    17281 ttcgtccatt acggcgtggc cctgggggac ggcgcggtgc tcgcgcccga ctcgttcctc
    17341 atgaagggcg aggccgtccc gccggatgcg cactggggcg gcaatccggc ccggcagacc
    17401 agcggccagg acaccggcga gggctggagg taggagccga tgaccacatc catgacggcc
    17461 cgcacccgcg gcgatcgcgg cgggtcggcc gacggcgcgt acaccagggt tccgcgctgg
    17521 acccgcgtcc cggttccggg caccgccgag cacctgacgg ccctcccgga gcagctgccg
    17581 gccgcgctgc gccgggtggc cgaccggctg cggatgccgc tgagttcggt gctgctggcc
    17641 gcgcacgcca aggtgctcgc cgtcttgtcc ggcgaccagg aggtcacgac cggctacctc
    17701 gccgagcggg gtggcactcc gctgccgagc cggctgacga ccgcggccgg ctcctggcgg
    17761 accctcctgc tggacaccca ccgggccgag gtggagctgc tgcggcgccg gggcttcccg
    17821 gccgccggaa ccggacctga accggcaccg gccgaggagt ccccggagac cgtgttcgat
    17881 ctgcccggtg cggacggcgg cccggccggt gaaaccgtgc tgtgggtcgc cctcgtacgc
    17941 cacgacggcc gggaggtgct gcgactgcgg taccggaccg aggtcctcga cgcgggctgc
    18001 gccgcccgga tcggcggcta ctaccgtacg gcgctcacgc tgctcgccgc cgatccggac
    18061 gccgaccacc ggcggcagtc cctgctctcc gccgaggaac tccggtgcca gctcgaagga
    18121 ctggccggac cgagccggcc actgccggac cgccggttcc acgagctgtt ccagcagcga
    18181 gtgcgggagc acccggacac catcgcggcc gtgcacggga gccggcggtg gacgtaccgc
    18241 gaactcaacg tccgcgccaa ccggttggcg cacgccctgc tggcccgcgg gctggcccgg
    18301 gaggacgtcg tcgcggtggt caccgaacgc aacctggagt ggctggccgc ggtcatcgcg
    18361 atcttcaagg ccggtggggt gtatctgccg gtggaaccgc actttccgcc cggccggatc
    18421 gcgctgatgc tctcgcgcgc cgggtgccgg caggtgctga ccgaacccgg cagcaccgcc
    18481 ggcctcgacc gggcccgcac ctcggtgccc ggcgtccgga ccctgttcat cgatgccgtc
    18541 tgcgcggcga gccccgcgga cagcgacccc gaggtccggg tcgggccgga ccagttggcg
    18601 tacatctact tcacctcggg atccaccggg gagcccaagg gcgcgatgtg tgagcacctg
    18661 ggcatgctca accacctcta cgccaagatc gacgacctgg cgatcgacga gggtcaggtg
    18721 gtcgcccaga ccgcgcccca gtgcttcgac atctccctgt ggcagctgct ctcggcgctg
    18781 ctggtcggcg gccggacgct gctggtcgag caggcggccg tgctggacgt gggacgtttc
    18841 ctcgacacgg tgggcgccgg acgggccacg gtgctgcaag tggtcccgtc gtatctcgat
    18901 gtcgtgctgt ccgccctcgc gcagcggccc ggcgcactgc cggatctgcg gtgtgtgtcg
    18961 gtcaccgggg aggcgctgaa gaaggagctg gtgcagcgct ggttcgcggc ccggcccggg
    19021 atccggctgg tcaacgccta cgggctgacc gagacctcgg acgacaccca ccacgaggtg
    19081 atggacgcgg tgccggacag cgagcgggtg ccgctcggac gccccgtcaa caatgtgcgg
    19141 gtgtacgtcg tggacgaaca cctggcgccg gtgccgctgg gcgccccagg cgagatcgtc
    19201 ttctccgggg tctgcgtggg ccgcgggtac atcaacgatc ccgagcgcac ccggctggcc
    19261 tttgtgccgg atccgcacca tccggggcgg cggctcttcc gggccggtga ccacgggcgc
    19321 tggctcccgg acgggaagct ggagttcctc ggccgccggg acagccaggt caagatccgt
    19381 ggtttccgta tcgagatggg tgagatcgag aacgccctgc tccgggtgcc cggggtcggt
    19441 gacggcacgg tggtggtgac ccagcgggcg gggcgcggca agcgcctggt ggccttctac
    19501 tccgggcggc acgcgctggc ggccgatgtc ctgcggggcc ggctgggcga gttgctgccg
    19561 gagtacatgg ttccgtcggc cttcctctgg cgggagagcc ttccgctgac cgccaacggc
    19621 aagatcgaca agaaggcgct ggaggccctc gccggcggac tcgacacggt cgaggacgac
    19681 taccacgcac cgcgtacgcc gacggaacga cagctggccg cggcctgggc cgaggtgctc
    19741 ggcataccgc aggaccggat cggccggcag gacaacttct tcgactgcgg cggcacttcg
    19801 ctgtccgccg tggccctcgc ggtctgcctg ggccgggcgg tctccgtcaa ggacctcacc
    19861 cggcatccgg tcctcgccga cctcgcccgg caggtcgacg ccagggccgg acgaccacag
    19921 ccccacccga acgacgccgc acaggccgtg cggtgcgaca ccgcacggcc ggctgcgtcc
    19981 cgagccgcca cggagaggag aaccaccatg gtgtcgtcac tctcgatctc gctgcccgaa
    20041 ctggagcggg aacccggcac acctccgatg ctgcgggtcg ggaccaccga cagcgcggcg
    20101 cgctgggcgg ccgagcgacg ggacgccctg cgcgccgtcg tcgccgagca cggtgcggtg
    20161 ctgatccggg gcctggggat gcgcgatccg gccggggtcg gcgccgtgct gcacggcctg
    20221 ggcgtcgccc cgctgaccga gcgggaggcg ttcgccctcc ggcagaccta ctccgagggc
    20281 gtctactcct cgtcgaaatg gccgccgaac cagccgatgt gcatgcacca cgagctgagt
    20341 tacaccctgg agttccctgg gctgatgctg ttcgcgtgcc tgggcgcccc caccaccggc
    20401 gggtccaccg gggtggccga ctcggcggcc gtgctggacg cgctgccccc ggtcctgacc
    20461 gagcggttcg agcgggaggg ctggctgctg acccgcagct accaccccga gatcggggcc
    20521 acgctggacc aggcgttcgg caccgaggac cgggacgccg tcgagcgcta ctgccgggcc
    20581 cacgccatcg acttcacctg gcagcccgac ggcggtctgc gcaccaccca gcaccgcagt
    20641 gccgtgctgc accaccccgt cagcggccgc cgctgctggt tcaaccagat cgcgttcctc
    20701 aacgagtgga cgatggcgcc cgaagtgcgg gagtacctga tcgacgagta cggccccgac
    20761 gggctgccgt tcaacacccg ctacggaaac ggcgaccccc tcgccgagga cgtcgtgcag
    20821 cagctcaacg aggtctacga cgcccacacc gcgcgccggc cgtgggaagc cggagacctg
    20881 ctgctcgtcg acaacgtccg cagcgcgcac agccgggagg ccttcgaagg gccgcgggac
    20941 gtggtggtgg ccctggccga ccccgtgcgc ctggccgact gcgcgccgac cgttgaggtg
    21001 aactgaccca tgaccaccgt ccgtcccacc ccgtcccggc ccacaccccc cgggccgccc
    21061 cccgcaccgt ccttcgcggt gatctccggt gcccaggtgc agcaggcgct ggagggacgc
    21121 gagaaggaga tcgtggacgt ggtcgaggcc acctaccggc tgcacggtgc cggagagtcg
    21181 gtgaacccgc cctcgtcctt cctccacctc cccgaccgcc cgtcgtcccg gatcatcgca
    21241 ctgcccgcct ccatcggcgg ccggacccgg gtggacggcc tgaagtggat ctccagcttc
    21301 ccgccgaacg tggccgccgg catcccccgg gcatcggccg tactgatcct caacgaccac
    21361 gacaccggct acccgttcgc ctgcctggag agctcgatca tcagcgcgac caggaccgcc
    21421 gcgtcggcgg cctcggcggc cgaccggctc agccgcgggc gcccccgccc gacccgggtc
    21481 ggattcttcg gcgcgggtct gatcgcccgc tacatccaca ccttcctgga aggcaccggc
    21541 tggtcgttcg acgagatcgg cgtgcacgac ctgtccgcgg agagcgcggc cggcttccgc
    21601 ctgtacctgg agcagtgccg aacgaccggg cgggtcaccg tgcaccacag tgcggaggag
    21661 ctgatccgct ccagcgatct gctggtcttc gccaccgtcg ccccgcagcc gcatgtccac
    21721 gaggtcgcgt ggttcggcca tcacccggtg gtggtgcatg tgtcgctgcg cgacctcgcc
    21781 ccgcagatcc tgctggcctc gaccaatatc gtcgacgaca tcgagcactg tctgcgcgcc
    21841 ggcacctccc cgcatctgac cgaacagctc accggaaacc gggagttcct gcacggcacg
    21901 ctggacgacg tgctggccgg ccgggtcgcg gtgcccgcgg accggaccgc cgtcttctcc
    21961 cctttcggtc tcggggtgct cgatctcgcg gtcggcaagt acgtctacga cgaggtggtc
    22021 aggtccgggg aactgcgggt cgtcgacggc ttcttccacg aactgcgccg gtacggatga
    22081 gcggccacgg tcggacggac cgtccaacgg tgcgctgccg caggtgagga gaccaacgtg
    22141 ccagtcatat ccgcgcccta cgcgttcaac gaggaggagc tctatgtcga cctccggtcg
    22201 atcttcggac actccctctt cctcaagtgc gagggcttca acttcgccgg ctcgatcaag
    22261 ctgaaggccg cgaccgagat ggtggagtcc gccgaacggg ccggtgacct gcgtccggag
    22321 acggtcctgg tcgagtcctc gtccggcaac ctcggcgtgg cactcagcat gatcgcggcg
    22381 agcaagggct accgctttct gtgtgtgacg gactcccgct gcaacttggc cacccggctg
    22441 atgatggagg cgctgggcag ccaggtgcat gtggtcgccg accaggagtc caacggcggc
    22501 ttcctcggcg cccggctcgc gtacatccgc aatctgtgcg cctccgacga ccgctgtctg
    22561 tggctcagcc agtacaccaa cccgagcaac tggaaggccc actaccgcag gaccgcaccg
    22621 gccatcgccc gcgccttccc gcggctggac ctgctgttcg tcggcgccgg caccaccggc
    22681 accctgatgg gctgcgcccg ctacttccgg gagtggcacc gggcggtacg gatcatcgcc
    22741 gtggacagcg tcggctcggt gaccttcggc ggcactccgg ggcaccggat gatccccggc
    22801 ctgggcatga gcgtccagcc gccgctgctc gacgagtcct acgtggacga cgtggtacgg
    22861 gtcgaggagg ccgacaccat ccgcacctgc caccggctgg ccaaacgcgg cttcgtgttc
    22921 ggcggctcga ccggcaccgt ggtcagcggc gcgacggact ggctcacccg gcacgacgcc
    22981 cacgaccgca cggcggtggc catcgccccc gacctcggcg agcgctatct cgacaccgtc
    23041 taccacgaca actgggtaca ggacctgtac ggcgagcacg tcctcgaccc cgccccgccc
    23101 gtcaacgccg atgtcgcccc gctcggcccc acctccccgg cggagccacc ggagccatcg
    23161 ccacgccgcc ggcagcggcg ccacgacgcc tgaggccggc gcctggcgga gccaccgagc
    23221 cgaccgcccc gcatccggcg gggcggtcgg ccacgtcagg ccgcgtgcgg cggggtcgcc
    23281 acccggtcag ccgctcccgc ccgccaggcg gtcggtgacc cactggtgga aggcgccgat
    23341 gtggtgctcg ctgggcacca gtaccccgcc gtcgcggtag gcgcgggagc tcatggccgg
    23401 ctgggtgcgc tcgcaggcgt cgaagtcctg ggcgttgacc cggtggaaga gttcgacgga
    23461 cttggagaca tcggtgccgg agtcgacgat ctcgggcagg tagagccagt cgcaggtgac
    23521 cacggtgcgg tcgggggcca tcgggaacat ccggtggacg atgacatggt ccggcacgag
    23581 gttgacgaag acctgcgggc ggacggtgat cgcgtagtag cggcggtcct gggtgtcctc
    23641 gatgccgggg agccggccga agccgtcggt gccgtccacg gtgaatccgg tggcctcgtc
    23701 ggcgaaggcg gcaccgtgcc cgacgtagta ctgggcggcg aaaccgtcgg cgaactccgg
    23761 gagcacgtcg gtgagttcgg ggtggatggt ggcgcagtgg tagcactcca tgaagttctc
    23821 gatgatgagc ttccagttgg cgcgtacgtc ataggtaacg cgcttgccga gggcgagtcc
    23881 ttcggtgcgg tagcggtcga gggaggccgt gtcccccagt cgttcgacgg ccgcgccgat
    23941 cacggtgtcc tcgaaggacg gcggctcgtc ggccaggcac acccaggcgt agccgagcca
    24001 ctcccggagc ggcacggtga ccagcccgcg ttcggcgcgg tcgacgtccg gcatcttctg
    24061 caggttgggg gcggccacca ggcggccgtc gaggtcgtag gtccaggcgt ggtaggggca
    24121 ctggaggttg cggcggacct cgccggactc ctcggtgcac agctgcgcgc cgcggtgccg
    24181 gcagatgttg aggaaggcgc gcagcgcacc ggcgcggttg cgggtgatca gtacgctctc
    24241 ccggccgatc cgtacggtgc ggaaggcgcc gggcttctcc aggtcggcgc tgcggaccgc
    24301 gcagaaccac agccgctcga agatcttctc ctgctcctgg cggaagatcc cggggtcggt
    24361 gtagtggtgg ccggcgaggg tggcgatcag gctcggggcg gcagcggtcg cgggtgtggt
    24421 gggtgccggc gaggactcgg tgggcgtggt cgtcatggtg gctctcctca agcggccgcg
    24481 gcggcgggcc ggcgggggtc gaacagctcg atggggtgcg cggtggcacc ggtcagcgcg
    24541 agatcggcga cgatctcgcc gaccaccggt acgaacttga agccgtgccc ggagaagccg
    24601 caggcgacgg tcaccgtctc cgggtgcgcg gggtgccggg tgatcacgaa gtgttcgtcg
    24661 ggggtgttgg agtacatgca ggtggcggcc ttgaggaagc ggccggggag ggcggggatg
    24721 cgcggggcga gctgctcggc catggcgcgt acctcgtggt cgtgcacggt gcgttcgatg
    24781 gtctccgggg tgcagacggt gcccttgcgg aagaacgcga ccttggcgcc gccgtcgggg
    24841 ccgtcgatcg acgggaagcc gtagatctgg acgccctgtg cgtcctccca gatgtagatc
    24901 gggtgctggt cggggacgaa gggcgcggtg ccgccgtccg gggcgaacca gtacatgacc
    24961 tgccgctcga tggtgaacgg cacgcccagg tcggtgagca gctggggcgc ccaggccccg
    25021 gggcagatca ccaactggcc tgcggtgtag gtgttttcgg gggtgtggac gcggaccccg
    25081 gcgccgccgg gcagctcctc ccagcgggtg accggctcct cgaagtgcag ctcggcgccg
    25141 tcctgcccgg cgagctggac atgcgcggcg acggtgtact ccggccggac cagaccggcc
    25201 cgttcctcgt acagcgcgac ctcgtccgcg gcgggggtca gggtcgggaa gcggcggcgg
    25261 atctcccggg gttcgagcat ctcgtgcggg aggtcccact ggcgggcgga ttccaggctg
    25321 ccgcggacgg tccggctgtc ggggcggccg agcatcaccc cgccgcacag ggtggcgatg
    25381 tcccggccgc tgtcccgctc cagcttctcg tacagctcgt acgagcgcag cagcagcggc
    25441 acgtaggcgg ggtcctcgaa gtaggactgg cgggtgatcc gcgaaccgcc gtggctggag
    25501 ccgcggttgt gcaccgggcc gaacttctcc aggcccagga cccgggcgcc ccgggcggcg
    25561 aggtggtggg cggcggcgct gcccatgccg ccgaggccga gaacgatgac gtcgtaggtg
    25621 ggagccatgc ggttgctcct tctgcgtacg gagggcgggc ggatcaccgg cgaaccgcgg
    25681 acgggcccgg ggctacctgc ggatgcgctc catctgcggg tcgatgaggg gctcttgggc
    25741 gacggtggca gggatcttct cgccgaagta ctcgatgtgt acggcggtgc cggggaccgc
    25801 cgcggcggcc ggcagccagg cgtaggcgat cccgcggccg agggtgtagc cgtaggcggc
    25861 ggaggtgaca tagccggccg gggtgccgtc cacgaggacg ggttccttgc cgaggacgac
    25921 ggccgcgggg tcgtcgaggg tgaggcaggt gagccggcgg gacgcggtct cctcgctgcg
    25981 gccctccagc gccgcccggc cgatgaagtc gcccttggcg gggcggaccg cgaagccgac
    26041 cccggcctcg tagggatcgt gttcggtggt catgtcatgg ccccaggcgc ggtagccctt
    26101 ctccaggcgg aggctgttga aggcgctgcg cccggcggcg atcaccccgt gctcctggcc
    26161 cgcctcccag agcgtgtccc acaggcgcag gcccatatcg gcggtggtgt acagctccca
    26221 gcccagttcg ccgacgtagc tgaggcgcat ggcggtgacc gggacatggc cgaggtaggt
    26281 ctgcttcgcc cggaagtagc cgaaggcctg gtgtgagaag tcgtcgcggg tcaggggctg
    26341 gaccagggcg cgggcgagcg ggccccagac gccgacgcag caggtgccgg aggtgctgtc
    26401 gcggacctgg actcccccac tctcggcttc gctcgagcgg gaggggcccc catcgtcggg
    26461 ggcgtgccgc agcagccagt cgaggtcggc tccgctgttg gcgccgatct ggaagcggtc
    26521 cggggcgagc cgggcgacgg tgaggtcgga gcggatgccg ccggtttcgt ccaggagcag
    26581 ggtgtaggtg accgcgccgg gcttcttcgc gaggttgttg ctggtcatcc gctggaggaa
    26641 ggcgagggca ccggggccgg tgacctccag cctgcgcagc ggggtcatgt cgtagagggc
    26701 gaccttctcc cgggtggcgc gggcctcggc ggcggcgatc ggtgaccagt agcgggccga
    26761 ccaggcgtca cgctcgggga gctggagccc ttcggcgagc ggggcgttgg cctcgtacca
    26821 gtgcgggcgc tcccagccgc cgccctccag gaagtacgcg ccgagctcct gctgccgtgg
    26881 gtagaagggg ctggtgcgca gcggccgggg ctgttccatg ggctgcagcg gatggatgac
    26941 gtcatagacc tcgatgaagt tctgggcacc gcggtcggcg atgtaggcgg gcgagcgctg
    27001 ggcgtcctcg aagcggtaga ggtcgcactc atggatgtcg atggcgggcc ggctgtccgt
    27061 catccactcg gcgacggcct tggcgacgcc cgcggagtgg gtgacccaga ccgcctcggc
    27121 cagccagaat ccgcgcagtt cgcgggattc gccgaggacc ggcataccgt cgggggtgaa
    27181 ggagaagacg ccgttgaagc cctcggcgac ccgggacgcg cccagtgcgg gcagcagtcc
    27241 gacgctgtcc tgccagctcg gcgcgaagtc cgccgcggtg aagggcagcg aggacggcat
    27301 gacatggggg tcccccctgc tcgaacgcag ctgagagctt gggggagcgt cgtcgaaggc
    27361 ggcgacggtg aacgggtcga cgggcatcgg gcggtgggcg taggagccga tgccgatccg
    27421 gtcggtgtgt tcgcggaagt agaggtcgcg gtcctggaaa cgcaggatcg gcttgctcgc
    27481 ctcgtcccgt gggtcgttga cgccggcgag ttcgggcagc ggctcggtgg tggcgtactg
    27541 gtgggccagc gggaggagtg gcacgtccac cccggccatc gcgccgatca ccgggcccca
    27601 gaagccggcg gccgagacga catggtcggc ggggaaggtg ccgcggtcgg tggtgacgcc
    27661 ggtgacccgg ccgtccgccc gctcgatccc ggtgacggtg tgccggtcca ggaagcgggc
    27721 gccgcgctgc tcggcccggg cgatctgggc gcggcaggcg agcacggcgc gggccagccc
    27781 gtcgtctggg gtgtggaatc cgccgtagag cgtggtctcg tccagcatcg gccacaggcg
    27841 cttgcactgc tgcgggccga tcagttcccc gcggatgccc caggaggccg cgagtccggc
    27901 cctgcggtgc agatcggccc agcgggcctc ggtggtggcg atctccagtc cgccgaccgg
    27961 gtggaagcag gacagcccgt ccacgtcgag ggagccgaac ttctggacgg tgtaggcggc
    28021 gaactcggtg agggtcttgg acgggccggt ctggaagacc aggccgggag cgtgcgaggt
    28081 ggagccgccg ggggccggca gcgggccctg ttcgaggacg gtgacatcgg tccagccgcg
    28141 ggcggtcagc tcatcggcga gggagcagcc gacgatgccg gcaccgatga caaccacacg
    28201 ggaactgggg gcgggcgtac gggacatgtc cctcctcctg ctggtcgggg tggtccactg
    28261 ggatgggtgt aacgccgtta caggaccacg acggagcgca gtacccggcc gtcgcgcatc
    28321 ttgtcgaatg cggactccac ctcgtccagg ccgatcgtct cggtgacgaa tccgtcgagg
    28381 tcgagccgtc cgctcaggta gcggtcaatg aggacgggga aatcgcggct gggcaggcag
    28441 tcgccgtacc aggaggattt cagggcgccg ccgcgtgaga agagatcgat gagcggcagt
    28501 tcgagccgca tgtccgggtc ggggacgccg acctggacca gcgtgccggc cagatcccgc
    28561 atgtagaagc cctggcggta ggtctcgggc cggcccaccg cgtcgatcac cacatccgcg
    28621 ccatggccgc cggtcagtcc gcgaaccgcc tcgatggggt ccgtaccacg ggagttgacg
    28681 gtgtgggtgg caccgaagcg ggtggcaccg tccagcttgt ggtcgtcgat gtcgaccgcg
    28741 atgatccggc gcgccccggc gatggaggcc ccggcgatcg ccgcgttgcc gaccccgccg
    28801 cagccgatga ccgcgacggt gtccccgctg ccgaccccgc cggtgtgcac cgcagcgccg
    28861 tatccggcca tcactccgca gccgatgaga ccggccgcct cgggaccggc gtgcgggtcg
    28921 accttgaccg cctgcccggc ggcgaccagc gtcttctcgg cgaaggcgcc gatgccgagc
    28981 gcgggggcga gcggggtgcc gtccagcagg gtcatcggct gggtggcgtt gcgggagtcg
    29041 aagcagtacc agggccggcc gcggcgacag gaccggcagc tgccgcaggg cgcccgccag
    29101 gcgaggacga catagtcacc cggggcgaga tcggtgacgc cgggcccgac ggactcgatg
    29161 acaccggccg cctcatggcc gaggaggaac gggaagtggt cgttgatcgc cccttcccgg
    29221 tagtgcaggt cggtgtggca gaccccgcag gcctgcacgg cgacgagcac ttctcccggc
    29281 ccggggtccg gtaccacaat catctgcggc tcgaccggtg cgccttgttt cgccgcgacg
    29341 acggcatgga cgtggtgtgg catgccctac ccctccgtgt tgcgcactgc acgactggtt
    29401 gcgcgatgag agacatagtg ggaacgccgg atcgacaccg tcaaggggta cgagccagct
    29461 cttggcaacg gatttcccgc gcgcccggac acaaaggcgg ggccggaacg cacgccccgg
    29521 ccccgcatcc gccacccgca cccgtcatcg ggtcaactgc cgtaccccat ccgccgcgac
    29581 agctccccgg ccgcggaaac ggtggccttg acgacctcgg gcagccgctc ctcggccagc
    29641 cggtaggcgg gcaccgacac actgatcgcc ccgatcaccg agccgtcggg cgcccgcacc
    29701 ggcgccgcga ccgcccgcag cccgagctcc agctcctcga tcgccaccgc gaagccctgc
    29761 tcgaccactt cggccagctc acggcgcagc gcggccgccg aggtgaccgt tcgctcggtg
    29821 agccgcggca acttccgtgc cagcacggcc tcccggaccg ccctgggctg gtacgcgagc
    29881 agcgccttgc cgctggaggt ggcatgcagc ggcgtacggc ggccgagcca gttctgcgcg
    29941 gtgaccgagg ccggaccgcg cgcctgcgtg acgttgaccg cggcatcgcc ctccagcacc
    30001 gcgatgttca ccgtctcccc cagctccgcg gccagctccc ggcagaccgg cgcgccttcc
    30061 tgggagatgt ccagccgtac ggccgccgct ccggccagcc gcagcacccc ggctgcgagg
    30121 tagtacttgc cgcgctcctg ctcctgtccg accagcccgc ggttctccag cacggccagc
    30181 agccggaacg cggtcgactt gtggacgccc agctcctcgg cgacctcggt cacggcggcc
    30241 tcgccgtgcc gggccaggat ctccagcacg gtcacggccc ggtccaccga ctgcacaccg
    30301 cccggctgct tcggcggctt ggtttccgcc tgcccctcca cgctgtccgt catctgttgg
    30361 atctcaccac ctggcacccc ggccgaggca cgggattcga aggtccggca tttccgggga
    30421 ccgcttgacg catccgctcc ccggctggat tctgttgcgc atggcgcctc atcgtgcgca
    30481 acgcgaaact cgatgatacc gaacagtaac aggggggtcc tgtgattcct gtctgcccgc
    30541 tcgccgacct gcccaccggc gagtccgtac gcatcgacac cgcacctccg atcgccgtct
    30601 tccatgccga cgggcagctg tacgccatcg acgacacctg cacccaccag gacgcctccc
    30661 tctcggacgg ctggctggag ggctgcctgg tcgaatgccc gctgcacgcc gcgtcgttcg
    30721 atctgcgcac cggagcggcc acctgcctgc cagcccgccg ggccgtgcgc acccaccccg
    30781 tgaccgtcga ggacggcatg atctacgtcc accaccacgc cgccgaggaa ggcaccgccg
    30841 catgaagtcg gtcgctgtca tcggggcctc gctggccggc ctctacgccg cgcgggccct
    30901 gcgcgcccag ggattcgagg gccggctggt gatcgtcggc gaggaacacc accgccccta
    30961 cgaccgcccg ccgctgtcca agggcttcct caccggcgcc accgccgacc agggtcaact
    31021 ggccctggcc gacgccgagg agatcgccga actggacgcc gaatggctgc tcggcacccg
    31081 cgccaccggc ctcgacaccc aggggcgcgc ggtgctcctc gacggcggcc gctccctgac
    31141 caccgacggt gtggtgatcg ccaccggcgc caccccgcgc cgcctccccg gcccggcgcc
    31201 caccggaacc catactctgc gcacccttga ggacgcccag gccctgcgcg cggagctgac
    31261 cggcggcccg gtcagggtcg tggtgatcgg cggcggcttc atcggcgccg aggtcgcctc
    31321 gtcctgcgcc gcactcggcc atgacgtcac ggtggtcgaa gccgccccgc tccccctcgt
    31381 cccccaactc ggcgacgcga tggccgggat ctgcgccgcc ctccatgccg accacggcgt
    31441 caccctgctc accggaaccg gtgtcgcccg cctgcacgac ggtggcgccg gtggcgacgg
    31501 caaccgtgtc accgcggtcg agctggccga cggccggctg ctccccgccg acgtggtcgt
    31561 catcggtatc ggcgtacgcc cccacaccgc ctggctcgaa ggctccggac tcccgctcga
    31621 cgacggggtg tgctgcgatg cgggcggggt cactccgcag ccccatatcg tggcggtcgg
    31681 cgatgtcgcc agggcggacg gcacccgcgc cgagcactgg accagcgcca ccgaacaagc
    31741 cgccgtcgcc gtccggaacc tgctggccgg ccgcaccgtc gcgacccacc ggagcctgcc
    31801 gtacttctgg tccgaccagt acggcgtgcg catccagttc gccggccgga gactgcccac
    31861 cgacaccccg cgcatcatcg agggctcgcc cgacgaccgc agcttcctcg cctgctacga
    31921 acgcgacggg cacaccaccg cggtcctggc cctgaaccgc ccccgcccct tcatgcgcct
    31981 gcgccgcgaa ctcgcccgcg ccgcccagcc ggtcaccacc tgacctcggc cggcggtgcg
    32041 gtgcgaggcg gcagcgggag ggtcggccgg atgacggctg tgggatgacc acagccgtgt
    32101 gacggcaacg gtgcggcggc cgcgggtggc gactgtggcg cagcagacag tgcgcggcgg
    32161 atgacggcgg cgccgtgggg tgttcggaac agcggaacgt ctgccggccg gcggcgttcc
    32221 gcgcccgcgc tctcttccta ggagacccac acgtgactgc cagcgccgcc gccacccgtg
    32281 cggcccagac gctctcccgt cccttcaccc tgggcggccg caccgtgccc aaccgcatcg
    32341 ccatggcgcc gatgacccgc gagttctcgc cgggcggtgt cccgggcgcc gatgtcgcgg
    32401 actattacgc acgccgcgcc gccggcggcg tcgggctgat catcacggag gggacctacg
    32461 tccggcaccc ggccgccgga accagcgacg ccgtcccccg cttttacggc gcggacgcac
    32521 tcgacggctg gagccgggtc gtggaagcgg tgcatgcggc gggcgggacg atcatgccgc
    32581 agctgtggca cgtcggtatg gcacgcaaag cgggcgcacc gccgttcccc gacgccccgc
    32641 cgtccggccc gtccggactc gccctcgacg gcaccccgtc cgggcatgcc atgacccagc
    32701 aagatctcga cgaggtcatc gcggccttcg ccgaggcggc agccacggcc gagcggctcg
    32761 gcttcgacgg agtcgaactg cacggtgcgc acggctactt gatcgaccag ttcctgtggt
    32821 cgggcaccaa ccggcggacc gatgcctacg gcggcagccg caccgcccgt acccgcttcg
    32881 ccgccgagat cgtggcggcc tgccgggcag cggtctcccc cgatttcccg atcctcttcc
    32941 ggatgtccca gtggaagatg ggcaactacg aggcccgcct cgccgagacc ccggacgaac
    33001 tccaggagat cgtggcgccg ctgacggacg ccggcgtcac cgcgttccac gcctcgaccc
    33061 gccgctactg gctgcccgaa tacgagggct cggacctcaa tctcgcggga tgggtcaaga
    33121 agctctccgg ccgccccacc ctcaccgtgg gctcggtcgg tctcgacaac gagttcctcg
    33181 cgacgttcgc tcacgaacag gccggggtct ccggtatcga ccggctgctg gaccggctgg
    33241 agcgggacga gttcgacctc gtcgccatcg gacgggccct gctcggcgac ccggagtggg
    33301 ccgccaagat cctggcgggc cgcaccgacg ccctggtgcc gttcgacgcc tcgatgctgc
    33361 gcacactgaa ctgacaccgg ccgcacgggg cgcggcccct cggggatgcc gcgcccccgc
    33421 cggcggccgc aaccgctccg ccgggcggcg gtcagcccgc gttcagctgg gcggccgcgg
    33481 cgtcgacggt ctgggtgagc agggtggcga tggtcatggg gccgacgccg ccggggaccg
    33541 gggtgatcag ggcggcgcgg gtgcgtgccg cgtcgaagtc cacatccccg acgttgcccg
    33601 ggttggagcc ggcgtctatc acgacggccc cgggcttgat gtgctcagcg cccaggaacc
    33661 ggggccggcc gacggccgcg atcagcacat cggcctcctt ggtgagcgac gccagatcgg
    33721 tggtgcggga gtggcagtag gtgacggtgg cattgcgccc gagcagcagc atccccacgg
    33781 gcttgccgag gatcgcgctg cggccgacca cgacggcgtg cttgccggcc aggtcgacgt
    33841 catagtgatc cagcagccgg atgatgccgc cgggcgtgca ggaagcaaag ccgtccaggc
    33901 cgaagctcat cgcggcgaag gagtggcagg tgacgccgtc gacatccttc tccggggcga
    33961 tcgcctcgaa cgcggcgcgc tcgtcgatgt gcgggccggc cgggtgctgc aacaggatgc
    34021 cgtgcaccga ggggtcgttc gacagcgcgg tgatcgtgtc gaccagctcc acggtcgtgg
    34081 tggcggcggg cagcgcgaca tgccgggaga ggatcccggc cttcgcgcag cggttgcgct
    34141 tcatacggac atacgtcacc gaggcggggt cgtcgccgac gagtacggtc gccaggcacg
    34201 gggccgtgcc ggtccgttcg gtgaggtccg cggcgcgccg ggcggcctgt tcgacgaggc
    34261 cgcgggccag tgcgctgccg tccatgaggc gggcttccgg ggacatgggc tgctcctgag
    34321 cgtcgtgtgg gatcgcccag gcgcgcggca ccggccgtgg atggccgagc cgctccccgg
    34381 tggtactcca cccaagcgcc agtcacggct cggcgcccac tgtaatcgac gtcgggaggg
    34441 ggcggcgtcc ggttttcccc gctacccgcc gccctgcccc ggtgcggaga ggggcggttg
    34501 gggcgcggcg gtggcttccc attggctgag gatgccgtcc cagtcgtgct gggcggcggt
    34561 gatggcattg gcatcccaga tgggctgggc gggctgctga tactgctggt gttcctcgta
    34621 cacccggtat tcctggtact gctgctggtc cgggtagtgc tggtacggct gttgcttcca
    34681 gggctcctgc tcgtagtgct cccgcggggg atgctgtggg cgctcgcgcc acgtcagaga
    34741 ggaagggtcc ggctgtgggg gcgggacgtt gaccagccgg cggtgccgtc ccgtgcggtc
    34801 cgagggggtg ggcggcatcg ggcggctgtc tgcggacagt tgttgtgcgc gggccaccag
    34861 cagccggaca tcgaggccga gttcggtggc cagggcggtg aggtcgacgc cgctgtgcca
    34921 gctgctcatc aggaccgcgt ccagcgccgg ggcccaggcc ggttcggagg gctggggggc
    34981 ggcggcctgg cccggctgcg gcggtggtgg cgtggcgtgc gcggcggggc ccggcgcggc
    35041 ggccccctga gcgggctgcg gggtgggggc ctgcgccgcg ggggcctggg gtgcgggctg
    35101 ctgcggtgcg gcggcgggct cgttcgggcg ctgggcgagc aggttcttgg cgacctcgcg
    35161 ggcgtcgtcc ttgcccaccg tgcgccgggc cagccgcact tcgcgttcgt ccaggccgag
    35221 cagatccgcc accaccgcgt cgctgccgac ggtcacggcg aacgcggcca gggtccgcga
    35281 tcggcgggcc tcggcctcgt cgaggagtcc ctgtgtacgg cggacctcgt catcgctgct
    35341 gcaaaacgcc tgtgcgagta ccgcgtggcg ctcccacaac tccctcggtt ccatgactgc
    35401 gacaacgttc cttcgtccgg attggaccgc ttcccggcaa tagatcactg catgaggtga
    35461 tattcgaggg agattcaccc ctgcctgcct ggcggaagta cgggcggctg caaaaatacg
    35521 cagtgacccc agcgtcgaag aatcgtttct acggccatga gcgtcccctc ttccggcacc
    35581 gtcgcaggtc acggaccgac ctccctcccc cgccccgggc agatgccccg gtggatcacc
    35641 gcgaaggtca tcaggcagac accggtgttc gccgggctgg tgaagcagtg gaccgagcgc
    35701 gccgccacgg tgcccggggt cgccgatccc gagtggcagc ggctggtctc ctaccgtgcg
    35761 ctgatggagg agaccgagat cgccctcacg gccctccggc cccatcgggc gcccgatgta
    35821 ctgcccccgc gaaagccgac ggtcccggcc gcccggcccg cccgtctgga cgcctgaagc
    35881 aggtcgacgg cggccgccgg gccgtcggcg cgggctgcac gccggccgga gtaccgttga
    35941 gttgtcgagg atttcccgct gtccggcggc tgcgccggca gcggctttga ccagcgacgg
    36001 agcccg
//
