LOCUS       NZ_CP050976            53344 bp    DNA     linear   CON 06-JUN-2024
DEFINITION  Streptomyces sp. RPA4-5 chromosome.
ACCESSION   NZ_CP050976
VERSION     NZ_CP050976.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RPA4-5
  ORGANISM  Streptomyces sp. RPA4-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9051652)
  AUTHORS   Nicault,M., Bontemps,C., Tidjani,R., Gelhaye,E. and Leblond,P.
  TITLE     Mining the biosynthetic potential for specialized metabolism of a
            Streptomyces soil community
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9051652)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 72x/76x
            Sequencing Technology :: Oxford Nanopore GridION/Illumina Nextseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012273495.1-RS_2024_06_06
            Annotation Date                   :: 06/06/2024 02:35:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,979
            CDSs (total)                      :: 7,887
            Genes (coding)                    :: 7,432
            CDSs (with protein)               :: 7,432
            Genes (RNA)                       :: 92
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 455
            CDSs (without protein)            :: 455
            Pseudo Genes (ambiguous residues) :: 0 of 455
            Pseudo Genes (frameshifted)       :: 276 of 455
            Pseudo Genes (incomplete)         :: 232 of 455
            Pseudo Genes (internal stop)      :: 23 of 455
            Pseudo Genes (multiple problems)  :: 71 of 455
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:36:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 789318
            Orig. end                         :: 842662
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP050976.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..53344
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="4"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..53344
                     /SMILES="NC([*])C(=O)NC(C(O)C)C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..53344
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:33344](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..33344
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            293..802
                     /locus_tag="HEP86_RS03705"
                     /old_locus_tag="HEP86_03705"
     CDS             293..802
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093623.1"
                     /locus_tag="HEP86_RS03705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03705"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_168477253.1"
                     /transl_table=11
                     /translation="MSRFTSRSPSREQASAAALAASELLEVLWGRGQEAARSAEVSPSQ
                     LRALLVLEKREGTNLRTLAEALASRPPAVSRLCDRLEAMGLAERSPSATSRREVELRLS
                     LRGRVLLEEYRAARSRDVTATLEQMEPADVAKLAAGLEAFHAAFARRAADEGGPSVRDD
                     SVADSA"
     gene            complement(993..1751)
                     /locus_tag="HEP86_RS03710"
                     /old_locus_tag="HEP86_03710"
     CDS             complement(993..1751)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983454.1"
                     /locus_tag="HEP86_RS03710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03710"
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_168477255.1"
                     /sec_met_domain="PIG-L (E-value: 3.6e-22, bitscore: 78.3,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPSLLAVFAHPDDESLSAGGALARHAADGARTAVVTATWANGT
                     HRAEELAEALRILGAGKPRMLGYADARVPQSAPGCVRFCEAPLDEAVGRLVTHIREFRP
                     DIMVTHDAYGGLPGHPDHVHTHRVTMLAAQAAGLAQLYPDAGAPWQPRVLYLATHPHSA
                     VPALRDVIGTRKAVYSVPDEQVTATVDVGPWIEQKIAAVLAHRSEVERGALPGLIAALP
                     PDARKRLFATEWYIRHTPITAAAPQTELTV"
     gene            1979..2728
                     /locus_tag="HEP86_RS03715"
                     /old_locus_tag="HEP86_03715"
     CDS             1979..2728
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891032.1"
                     /locus_tag="HEP86_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03715"
                     /product="DUF2071 domain-containing protein"
                     /protein_id="WP_168477257.1"
                     /transl_table=11
                     /translation="MLSELAAPEPVTAEPPHSLAPVLLTQSWLDLAFLHWAVDPAEVAP
                     LLPAGTVPDTFDGATYVGLVAFRMHRVGWFKLPGIPYLGTFPETNVRLYSVDGSGRRGV
                     VFRSLDASRLIPVAFARSVVRLPYLWSRMSVRHDGDTVSYASTRRWPGPRGAHCRITVR
                     KGAPVTAPTALEHFLTARWGLHHTFHGQPSYLHNAHPRWPLHRAELLHLDENLIAAAGL
                     STPLGQPLSVLYSPGVPVTFGRPTPGA"
     gene            complement(2816..6619)
                     /locus_tag="HEP86_RS03720"
                     /old_locus_tag="HEP86_03720"
     CDS             complement(2816..6619)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606836.1"
                     /locus_tag="HEP86_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03720"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_168477258.1"
                     /transl_table=11
                     /translation="MPSSLTPKHPTSAPEAEPHETPLLLSVLGPMSARHDGHDLPLGPP
                     RRRALLALLLIRLGRVVPTELLIEELWGEEPPRQSVATLQSHISHLRRVLQPASGPDRP
                     TVLRHRAHGYVLELAPEQIDACRFERLVAEGRLLLERRDPRAARDRFTAALSLWRGSPY
                     AEFDGHPPLSDESSRLEDVRLTAVESCAEAQLALGEAQEVAADLDREARLHPARERLVG
                     HLMTALSRLGRQAEALEAYERTRVHLEEEFGVGTAAELRRVRTAILRQEPGAGGPTAGL
                     MTGSVTGSLTGPLTRPAAGPRPGSPGPAGPALPATALGGATENDGEGTQGAEERPPCAA
                     QEPERPTAAEAFGGIGGGTAAPDERSAAEEAGTTGTQADGPARGPGHAHRPTTITAYSQ
                     PTTTPPTTTPTRPATENSRSTHNNSRSTTESWQSTTENWPSPTENWQPPSKNWQSPTAN
                     ADEHPRPTPPDAKTPEYDPNTESSRPVCGSPGAQSPFTGRSEELQRLTAAAASALAGHG
                     HVAGVLGPAGVGKTRLLLEFALRLGTPQAGRKGADEDASGLEVIWSHCFLGEGVPPYWV
                     WTQILRRLSTTRPDAFRAAAEPFGTLLAPLLPERADRPGGPAPESDWGRARFLTHDAVC
                     EVLLALAAQRPLVLLMEDLHWADTASLDLLRLLSTRSQGHPLGIVLTAREYEIESDATL
                     RRMLSEVLRGPRTETLRLGGLSRHAVAALVGPGVDARVVEVLHRRSEGNPYFVMQLLSL
                     LGDARSLRRPDAVDVLLTRVPTGVREALHQRFATLPDTVLRVLRLCAVIGTEIDTDLLE
                     RTATEDEPVTKALELAIRAGLLGEDRHHPERLHFTHALVQETLIDELAREDRQRLHARV
                     VEGISTRRLGQLADEEIERIAHHAWHAKSALPAADTLPLLLRAAEQAEQQLAYEQVETW
                     LRRAVHLVGLLPPGDPSAASLNQRLHIQLGQVLATTRGYGHAEAETALARGWALSAAAR
                     SPEDPSVLWALCAAYIVTGRYDASRQFSHLLRDLADGTGQPVAVLGAAYGEGIVLHVRG
                     QLRQALAELEHGVAMADGYANEGHSLARTFQHDPRVSCRSYDTFTRWLLGDRTTATARR
                     RELLRLTEYDSRPSDRCFALYVDAVVAAWEDDARTARSSGAEGVRLADEHGLLYWKGML
                     GVLEGWGRTHCGQEDGLTLMHSSLAELRNSRTYLRRPLHLGLLAQAQHHAGRTEDAKTT
                     FRALLAAVGQSNEHVYLHPDLPATRLLHDLLGRGAAESVATG"
     misc_feature    complement(5114..5116)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6712..6726
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.8"
                     /tool="antismash"
     misc_feature    complement(6843..6856)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     misc_feature    complement(6973..6988)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.41"
                     /tool="antismash"
     protocluster    7170..36972
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[17169:26972]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      17170..26972
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     misc_feature    7536..7548
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.09"
                     /tool="antismash"
     gene            7536..8366
                     /locus_tag="HEP86_RS03725"
                     /old_locus_tag="HEP86_03725"
     CDS             7536..8366
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="HEP86_RS03725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03725"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_282189738.1"
                     /transl_table=11
                     /translation="MHYAILGPLRLVINGEPRPIRSRNLSIILATLLVKAGSIVTVNDL
                     IGEVWAQPPQRARDAIYVHISKLRQQLGNKSQDDVIWSQFPGYLMRLHGEQLDLQLFHR
                     HRIDGHRNMVNGDYKAAARDWKSGLSLCRGTLLGGAYAGPILGSFDSWLEQSRTDCIEL
                     TAWSQLSAGLCHEVIDFLSLHLTRYPLNEILYQQLMLAFFLSRHRAQSLRIFHRARQTL
                     AGELGINPGGDLRMMQDIVLSDDVSRAKRVIASAVASRVSDLRPSGTPTTPSFC"
     misc_feature    7608..7610
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    8394..8408
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
     misc_feature    8411..8429
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.06"
                     /tool="antismash"
     gene            8509..9786
                     /locus_tag="HEP86_RS03730"
                     /old_locus_tag="HEP86_03730"
     CDS             8509..9786
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020679111.1"
                     /locus_tag="HEP86_RS03730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03730"
                     /product="cation:proton antiporter"
                     /protein_id="WP_168477262.1"
                     /transl_table=11
                     /translation="MNAPDASSMLLALAVLVLVCQGMAALARRLGQPSVVGEIVGGVLL
                     GPTLFGGRLTDTLFPTDIRPLLGAFANVGVALFMFLVGLEFDRRVIRQQAGTMGWLGVG
                     ALVVPFGLGSLFALWLLDAHPSSQPTAFVVFLGTAMAVTAFPVLARIIVDHGLLNSRVG
                     GLALALAAVGDVIAWTVLAVVVATVGADGHSWRLLLLLPYAAIMVFVVPRLLSSRLVNR
                     LPQRATVLLVMAGVLASGAATEWMGLHLIFGAFLFGLVVPRTGLRGGFREGLGTSVEPL
                     ASFLMPIYFVVAGFRVDLSHLDADAIGELLLILLVACGGKLLGVYSGARAARLDHRSAL
                     GLATLMNVRGLTELVLLMVGLSMGLLDPDLYSLMVVMAVVTTVASGPLLRSSIGSSMKD
                     EEALGARVPVPSAPVEEREQPQAGRP"
     misc_feature    complement(8537..8552)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            9864..10568
                     /locus_tag="HEP86_RS03735"
                     /old_locus_tag="HEP86_03735"
     CDS             9864..10568
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014862.4"
                     /locus_tag="HEP86_RS03735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03735"
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_168477264.1"
                     /transl_table=11
                     /translation="MSPLDISLADLIARLDEELPEANELARISEARLRAQTLSDLGDQL
                     IDHYVSKAKQTGASWTEIGDAIGVSKQAAQQRHAPGPFERYTELNRHSIVLAQEAARTH
                     KHDFIGTEHMLLGLLGEPRGLAYEVLLAKTGSEQRIRDAIEEALPPAGEKALRGHIAFR
                     PESKEAIEQAGRASADLGHDWVGTEHTLLGLIRAEESPAAQILRTLGFTSDELRETVKT
                     EVAQRSATRDER"
     gene            complement(10812..11495)
                     /locus_tag="HEP86_RS03740"
                     /old_locus_tag="HEP86_03740"
     CDS             complement(10812..11495)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941245.1"
                     /locus_tag="HEP86_RS03740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03740"
                     /product="nitroreductase family protein"
                     /protein_id="WP_248000996.1"
                     /sec_met_domain="PF00881 (E-value: 1.8e-28, bitscore: 98.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLETSLEPLVAERLIRGRRAVRAYRPDPVPDTVITAVFALAAA
                     APSHSNTQPWSVDVVSAGARQRLGEALVQAAESGKPSPDFPLHPYTGAAAERSYAAGAI
                     MHEARGIARSDRAGRRRAFLEGLRFYGAPHVALLSVPADADERMTADLGIYAQTLMLAM
                     TAHGVASCPQGVLGFYADAVRSVLGPSTDKLLFGISFGYPEPGAAATMPVIPRAPLAET
                     TRFHE"
     misc_feature    11447..11461
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     misc_feature    11568..11583
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.46"
                     /tool="antismash"
     gene            complement(11627..13234)
                     /locus_tag="HEP86_RS03745"
                     /old_locus_tag="HEP86_03745"
     CDS             complement(11627..13234)
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037824.4"
                     /locus_tag="HEP86_RS03745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03745"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_168477266.1"
                     /transl_table=11
                     /translation="MNTIPNTRQPVSLRSDVVVEPLIDHWYAWSHLLSPGTAARNIARR
                     QLPIMTSYLEAPAVHQRSSRTPALAGGPFMDLGGDRSADVEALIADTRRRAARLLEFDT
                     AVDTLQDLLAKAAPGAPLEELYPLVPEPLQGYVELVYDLQDNASFRLIEALLYRSDYAS
                     TDGQSLALEPLRADRRPFALSTPRLATDERTVLPVPFHHPGVDVMFSTLRTPRPLGEVA
                     DALELTSDTARKLAPYFTAADAPAKATRREPVTEPRIRYLGHACVLAENDQGAILVDPL
                     LPPAFPGAGPRLVDSDLPDYIDHVLITHGHQDHLVLESLLRLRTRIGTIVVPRSDAGSL
                     QDPSLRLALEAAGFPRVIELGELQQIETAMGRLTAVPFFGEHGDLAISKSAWLLESDGR
                     SVLFAADTSTIDPAAYAHVRRAIGKVDVLFLGMECEGAPLTWLYGPLFTHEPAREMAVR
                     RRLNGNDDIGAMALAEALGCDRAYVYAMGHEPWVWYLTTTTFDENAAPVQAAERFVAAC
                     RGRGIEAQRLHGSCDLPW"
     gene            complement(13231..13755)
                     /locus_tag="HEP86_RS03750"
                     /old_locus_tag="HEP86_03750"
     CDS             complement(13231..13755)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012897.4"
                     /locus_tag="HEP86_RS03750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03750"
                     /product="3-isopropylmalate dehydratase"
                     /protein_id="WP_168477268.1"
                     /transl_table=11
                     /translation="MIISGLAYGVGDFVDTDVMSPGRYEPYEGPDQLARIALVDYPAKT
                     PFVDPDTGTSPFKVIFAGTEFGCGSSRETAPQALHYAGARIVIAKSFGNIFFRNCVNMG
                     LLLPVVIDHGFDESITGAPVSVDVSRRVVTCADRQMEFADLGALQGIVDGGGLTPYTLD
                     RVRAGQGRRVR"
     gene            complement(13752..14816)
                     /gene="speB"
                     /locus_tag="HEP86_RS03755"
                     /old_locus_tag="HEP86_03755"
     CDS             complement(13752..14816)
                     /EC_number="3.5.3.11"
                     /GO_function="GO:0008783 - agmatinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="speB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941255.1"
                     /locus_tag="HEP86_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03755"
                     /product="agmatinase"
                     /protein_id="WP_168477270.1"
                     /transl_table=11
                     /translation="MTPSTPGGPGGPAADAPQDYDDAVRRADYRGVFGPETSFLGLPRC
                     EQSPAGYAGADVVILGAPFDGTTSHRPGTRFGPQAIRRTDYLPHVPYRPHLGLGVDPFT
                     ELKIVDAGDVPTPPGETERAHQLLERTVSEVVAAGAIPFTLGGDHSIAWPTMRGIASRR
                     GPGTFSVVHFDAHADIGDTSDFGAEYGHGTVMRRLLESGTVPGDRFTQIGLRGYWPGPR
                     TLQWAAGLGVRSLTMSELRSRGLDTCLDDVLDQIGPGPLYLTIDIDVVDPGMAPATGTP
                     EPGGLTSRELLDAVRTCAQRVDLVGAEIVELSPPYDGPGEITAYLANRIVLEVLSGMAW
                     KRRAASAGNEGLPS"
     gene            complement(14813..15901)
                     /locus_tag="HEP86_RS03760"
                     /old_locus_tag="HEP86_03760"
     CDS             complement(14813..15901)
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012407.4"
                     /locus_tag="HEP86_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03760"
                     /product="isocitrate/isopropylmalate family dehydrogenase"
                     /protein_id="WP_168477271.1"
                     /transl_table=11
                     /translation="MTPTTKPTVLVLPGEGIGPEVVGAARHVLEHVLDRAGLDATIREH
                     AVGLPAYERTGQWLPDAVRDEIDQVAATPHGAVLFGATADEPIGELRSRYDLFANLRPA
                     RPLRALRDVSPLRPERLDGVDLLLVRELVSGVYYGRRRTGVDAGQRWAGQEMYYREDEI
                     RRIVRCALEHAEARRRRLTLVHKANAIPDVFGLWLEVLAEEAPAFPDVEVRDMYADTMA
                     MQMVLRPADFDVIVTSNLLGDVLSEITGAVCGSLGLLPSATLSPTGFALYEPVGGTAPD
                     LAGTGHANPLGTIASVELMLRHTFGAPRWADHLADGVERAVESCRTPDIAGPGSAPCTT
                     KEMAAAVCDAFDAVVAEEETQR"
     gene            complement(15905..17173)
                     /locus_tag="HEP86_RS03765"
                     /old_locus_tag="HEP86_03765"
     CDS             complement(15905..17173)
                     /EC_number="4.2.1.33"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF001614.1"
                     /locus_tag="HEP86_RS03765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03765"
                     /product="aconitase/3-isopropylmalate dehydratase large
                     subunit family protein"
                     /protein_id="WP_168477273.1"
                     /transl_table=11
                     /translation="MIPQTMTHKILARAAGRDHVVAGEIVEVGIDMAFTHDPVCEGLRR
                     EFRDAFGPDATVWDPERIALFEDHLVPAKDAESRRLAAGMTQFATEQGITHHYPYGENY
                     GICHVMMCDEGLVQPGTVVLGTDSHSVTYGAFNAFGSGVGMIDMVNAFYTGDLWFRVPE
                     SIEVRIEGELPPGVLAKDVILTLIGDLGMGGASGRSIEFTGSTIDTMSVEERMTLCNMV
                     VEAGAVNGIMALSPAAAEYLAARPRTVPYEPVTSDPGAPFARRLEYSAEKLRPAVAYPH
                     RPDNVHSIDEAMADHIRVDQVYIGSCTGAKYDDIEVAAAELAGKRVAPGVRLMIVPATM
                     GIYRRLALSGTMSTLLAAGAVVESPGCKACYGAHGGVVGDGEVCLSTTNRNFRGRMGNP
                     KSSVYLASPIVAARSALAGRITE"
     gene            complement(17170..18420)
                     /locus_tag="HEP86_RS03770"
                     /old_locus_tag="HEP86_03770"
     CDS             complement(17170..18420)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012885.4"
                     /locus_tag="HEP86_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03770"
                     /product="hypothetical protein"
                     /protein_id="WP_168477275.1"
                     /sec_met_domain="HMGL-like (E-value: 2.7e-39, bitscore:
                     134.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGSAEELFTWNPRSRGITHVGIEDDSLRDGLQGAFVHHPSVEVK
                     KTLVESAAAIGVEAAMLGFPSSSAGALAEAAELVEHLDRRGLPMVPRFLALADPASIAP
                     ISRLNRGTDRDVWADFFVGCSPLRRRVEGWTLDSVLERITAAGSAARDDGTRFGVSLED
                     ATRTPPEELEQLVHVAVGAGAEVLTVCDTVGESTPEGAAQIVRAVRAAVQRALAGLPSG
                     NHGAAVKIWWHGHDDRGLAVANAIAAAEAGADTISGAFLGLGERAGNTALESVLMYLYQ
                     AGHQGYRMDRVVEHCRRLAEATGSPVRRNAPLIGDQAFATCTGTHVAALVKARRWGREA
                     EDLVFSSVPAAVLGRTQSIMVGPTSGRAAAREALASVGAPVDDVNVDAVLARAHAHDRW
                     LEPSEIRELLEVRGVSA"
     misc_feature    complement(18737..18752)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     gene            18799..20004
                     /locus_tag="HEP86_RS03775"
                     /old_locus_tag="HEP86_03775"
     CDS             18799..20004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941271.1"
                     /locus_tag="HEP86_RS03775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03775"
                     /product="KamA family radical SAM protein"
                     /protein_id="WP_168477277.1"
                     /transl_table=11
                     /translation="MPQAEWSDPRWQMTHRLRRPSQLRDVIKLTEDEEAALGGDDLFRV
                     DITPYFLSLIDGDDPHCPLRLQVIPSSREMEAFDGRLPDANSEIEHEPVRGIIHKYPDR
                     LVMLVTSSCTSYCRYCTRSRFVGDGKQNYSHSDWAEQLRYIRDSPQVRDVLITGGDPLS
                     MARNRLAEIITELRAIPHVEIIRIGTRAPVFNPFVVDDDLCKLLADNHPIWLNIHVNHP
                     YELTPELAQACSRLSSAGVPLGAQTVLLAGINDSVEVQRRLCTELVRMRVRPYYLYQCD
                     SVRGAGHFRTSVTKGIEIIEGLRGHISGFAVPTYVVDSPGGGGKIPVGPNYLLSLSPER
                     AVLRNWAGEVSEYHGPSGYRSGTTPPLRGPKSHRAPTEVPTVSDRLSAPQTPAEDAEGF
                     EV"
     gene            20001..26972
                     /locus_tag="HEP86_RS03780"
                     /old_locus_tag="HEP86_03780"
     CDS             20001..26972
                     /NRPS_PKS="Domain: AMP-binding (193-589). E-value: 7.5e-89.
                     Score: 290.1. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03780_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (709-776). E-value: 6.6e-13. Score:
                     40.7. Matches aSDomain: nrpspksdomains_HEP86_RS03780_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (794-1096). E-value:
                     5.6e-79. Score: 257.2. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03780_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1248-1671). E-value:
                     1.1e-107. Score: 352.1. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03780_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1792-1859). E-value: 3.4e-18.
                     Score: 57.6. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03780_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1881-2181). E-value:
                     6e-54. Score: 175.0. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03780_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="HEP86_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03780"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_168477279.1"
                     /sec_met_domain="Condensation (E-value: 8.8e-58, bitscore:
                     194.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-106, bitscore:
                     354.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7e-11, bitscore:
                     41.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSVHSGPAVQAPESDGVRHSVDEVLAAAVVVLGRYEDRDQLALD
                     ITAAPADAAPGTAAVHRVVVDCAPSATFAQVRTGLAGQLPAPRPAGRWTVQVADPDDLG
                     PDAGARPAGRGELTVRQGADPTLVLDHPHASGRGLHEAVTRVLAAGTAHPGQELAELPV
                     LSPGETDIQRQRLTGEPSPVPAETTIHELIRDAAGRHPERVAAACDAESLTYEELVERS
                     DRVAGAVLAHGIARGEVVAVVAERSCAVLTAALGVLTAGGAFFLLDPTLPAARREQLLA
                     AAGVRLVVTTRAGRAALTADRPALVLEDLGSADAVGDRPKLHGDDLAYLMFTSGSRGKP
                     KGVLVRHRSFVNRQRWLIDRLGLGPEDVSLGRTALSFDPAVCEMFRLLPVGGRVWFLPT
                     GHERDPARVLDAIERRRVTVVDLVPSPLRSLLEHVSTLGLFSAVSSLRWVLAGAETLHP
                     WLVELFEEVAGRRGGAHLLNGWGATEVCVDVTSFDCSVGPVREPVPVGRPIPGTGVAVL
                     DRHGRFTPLGVPGELFVRGRCLAAGYLNDTELTDERFVQRPVAGPELLYRSGDRVRWRA
                     DGNLEFLGRLDDELSVRGQRIAPAEIEAVLRRHPAVDDALVRTVGEGASEAGSERLIAW
                     VTHDASSAPPDPGELRTHLAEFLPSTMVPEAVHVLDAFPRTVHDKVDVKALPTTSPARA
                     DDSATGPLPSPSASVEDTLAALWREVLNGAASGPDDDLIARGATSLDAARVATRAAASL
                     CGRLDVITIFAHPTIRAQAAVIRDCDHASCRVARLAPTPPAETAPASHSQLRHWITSRF
                     DATSSAYNIAVGIELAEVPDPAVLRTALDELTVRHEILRTTFALEDGELLQRIRPPQPG
                     WVPVEVGAAADPSRHLRAVSERPFDTEAGPLLRLGLITPADTERTPDRGTVLYLVIHHL
                     ISDTWSLTLLLTELAARCRALATGDGPAELPPARLQYRDYAAWEQARLAGPAGQRMRGF
                     WTDRLAGPLPALGLPLDAPRGSAKVPGADVQRFALDPEVTDALRSWAGGNRATMFMALL
                     TATSAWLHRLTGQRDLVVGTPVAGRPHLDLEDVLGSFVNSVALRVAVDPEASPEELLAQ
                     VRSTALEAFAHEEYPLDLLVRDLGLVRDPERSALFDVMLVLQNAPGARTESVWGEPSAR
                     RVDVDRGVGKLDMIVTFVEDEDGLRGEIEYDSHLFTSTTIERWLAGLSRTIAALPHSGG
                     ATAAAVARSALDAPAEPVLLHTAVERHARLTPERTAVVCEDRVLTYGELNSRANRLARR
                     LRDEFGVTPGKMVGYAVERSERVPVIQLAVLKAGGAFLGIDPAHPEARSRAVLEDARPV
                     LLVVDGHEQGCRPEGVEWLPVLALDDAPELSDDGEGAADLTPAAGPDDPAYVIYTSGST
                     GTPKGVMVEHRNALALLWAGGWPFDFRDDDVWTSTHSFAFDFSVWELHLPLSRGARVVI
                     IPEATRRDPRKLLPVLVRERVTVLSQVPSTFERAVDALDRRPELAPTSLRYVIFGGEPI
                     NPGAVRRFAGHLPGVDLVNGYGITETTVFTTFKRLDLSEAPEAADAPPSDMQNIGRPIG
                     TMSVELRDMDGKLVPEGSVGEIVISGPAVARGYLGRPEETARVFGVHADDPGAGGHDGR
                     PPRRWYRSGDLARRLPSGDLVFVGRRDRQVKIRGYRVELEEVRSAILSTGLLAGDAVTD
                     VRTGPNDTPTMVAYLDDRDRERIPALRQRLQELLPAPMIPASFVTVDDWPTTANGKADL
                     DALRARYSGDRQTPAEDESEATTDQGATGGAPDTLASLGELWGELLGHCDLGPDDNFFT
                     VGGHSLLAVALVTRVEENLGVVLGLEDVLTHATLAGQAELIDARRTPAEEQPATGPDPL
                     PAAPVSGDHPLSPAQSEFWLLDQFRAPGTPAATPEILELGTPWDPAADRAAFARLVESF
                     EILRTDFPLADTHPRQRIHPHGHEDALRLTDLSRSPTAEDLRNLLDEEAARPLDLTEGP
                     LFRLHLVRRPDTSTLAVVTAHHIVWDGMSCDVLTRWWQQDRQAQRAGDVTPRRPARQFR
                     DIAAQQLDYLRSPEGRAELAWWTGRLTGAHRTRPDLTPLGIGYPSGPRDFLGCRHRVTV
                     DAGRTRALQALCSDARTTLFAGLHAVVKAFLFALTRQTDLVVMSPVSLRDGRVLEEQLG
                     PLINTVALRDHVEPREPFRALLDSVRHSVVDALAHRRIPPGDIGRALGLDADAPLADIG
                     LTLQPRTGTTEAAWTEEVFGAHTPLWFDITEQADTLHVEIVAPRARIDDDTLAELGRAF
                     LRIVGLLLDHPDAPLDQAVDARPAESPAPLTIELRY"
     aSDomain        20580..21767
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03780_AMP-binding.1"
                     /evalue="7.50E-89"
                     /label="HEP86_RS03780_AMP-binding.1"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="589"
                     /protein_start="193"
                     /score="290.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RDAAGRHPERVAAACDAESLTYEELVERSDRVAGAVLAHGIARGE
                     VVAVVAERSCAVLTAALGVLTAGGAFFLLDPTLPAARREQLLAAAGVRLVVTTRAGRAA
                     LTADRPALVLEDLGSADAVGDRPKLHGDDLAYLMFTSGSRGKPKGVLVRHRSFVNRQRW
                     LIDRLGLGPEDVSLGRTALSFDPAVCEMFRLLPVGGRVWFLPTGHERDPARVLDAIERR
                     RVTVVDLVPSPLRSLLEHVSTLGLFSAVSSLRWVLAGAETLHPWLVELFEEVAGRRGGA
                     HLLNGWGATEVCVDVTSFDCSVGPVREPVPVGRPIPGTGVAVLDRHGRFTPLGVPGELF
                     VRGRCLAAGYLNDTELTDERFVQRPVAGPELLYRSGDRVRWRADGNLEFLGRLDDE"
     aSModule        20580..22328
                     /complete
                     /domains="nrpspksdomains_HEP86_RS03780_AMP-binding.1"
                     /domains="nrpspksdomains_HEP86_RS03780_PCP.1"
                     /locus_tags="HEP86_RS03780"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20763..20804
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0001"
                     /evalue="1.50E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="268"
                     /protein_start="254"
                     /score="6.1"
                     /tool="antismash"
                     /translation="LGVLTAGGAFFLLD"
     CDS_motif       20982..21041
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0002"
                     /evalue="3.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="347"
                     /protein_start="327"
                     /score="25.7"
                     /tool="antismash"
                     /translation="AYLMFTSGSRGKPKGVLVRH"
     CDS_motif       21573..21662
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0003"
                     /evalue="3.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="554"
                     /protein_start="524"
                     /score="41.8"
                     /tool="antismash"
                     /translation="PLGVPGELFVRGRCLAAGYLNDTELTDERF"
     CDS_motif       21744..21809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0004"
                     /evalue="3.40E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="603"
                     /protein_start="581"
                     /score="22.7"
                     /tool="antismash"
                     /translation="FLGRLDDELSVRGQRIAPAEIE"
     aSDomain        22128..22328
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03780_PCP.1"
                     /evalue="6.60E-13"
                     /label="HEP86_RS03780_PCP.1"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="776"
                     /protein_start="709"
                     /score="40.7"
                     /tool="antismash"
                     /translation="EDTLAALWREVLNGAASGPDDDLIARGATSLDAARVATRAAASLC
                     GRLDVITIFAHPTIRAQAAVIR"
     aSDomain        22383..23288
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03780_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.60E-79"
                     /label="HEP86_RS03780_Condensation_LCL.1"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1096"
                     /protein_start="794"
                     /score="257.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLISDT"
                     /tool="antismash"
                     /translation="ETAPASHSQLRHWITSRFDATSSAYNIAVGIELAEVPDPAVLRTA
                     LDELTVRHEILRTTFALEDGELLQRIRPPQPGWVPVEVGAAADPSRHLRAVSERPFDTE
                     AGPLLRLGLITPADTERTPDRGTVLYLVIHHLISDTWSLTLLLTELAARCRALATGDGP
                     AELPPARLQYRDYAAWEQARLAGPAGQRMRGFWTDRLAGPLPALGLPLDAPRGSAKVPG
                     ADVQRFALDPEVTDALRSWAGGNRATMFMALLTATSAWLHRLTGQRDLVVGTPVAGRPH
                     LDLEDVLGSFVNSVALRVAVD"
     aSModule        22383..25577
                     /complete
                     /domains="nrpspksdomains_HEP86_RS03780_Condensation_LCL.1"
                     /domains="nrpspksdomains_HEP86_RS03780_AMP-binding.2"
                     /domains="nrpspksdomains_HEP86_RS03780_PCP.2"
                     /locus_tags="HEP86_RS03780"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       22449..22565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0005"
                     /evalue="1.20E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="855"
                     /protein_start="816"
                     /score="40.2"
                     /tool="antismash"
                     /translation="SAYNIAVGIELAEVPDPAVLRTALDELTVRHEILRTTFA"
     CDS_motif       22779..22838
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0006"
                     /evalue="3.40E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="946"
                     /protein_start="926"
                     /score="19.7"
                     /tool="antismash"
                     /translation="IHHLISDTWSLTLLLTELAA"
     CDS_motif       22896..22934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0007"
                     /evalue="3.60E-03"
                     /label="C4_LCL_164-176"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="978"
                     /protein_start="965"
                     /score="10.2"
                     /tool="antismash"
                     /translation="QYRDYAAWEQARL"
     CDS_motif       23187..23276
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0008"
                     /evalue="6.60E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1092"
                     /protein_start="1062"
                     /score="41.0"
                     /tool="antismash"
                     /translation="DLVVGTPVAGRPHLDLEDVLGSFVNSVALR"
     CDS_motif       23325..23444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0009"
                     /evalue="5.40E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1148"
                     /protein_start="1108"
                     /score="47.7"
                     /tool="antismash"
                     /translation="RSTALEAFAHEEYPLDLLVRDLGLVRDPERSALFDVMLVL"
     aSDomain        23745..25013
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03780_AMP-binding.2"
                     /evalue="1.10E-107"
                     /label="HEP86_RS03780_AMP-binding.2"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1671"
                     /protein_start="1248"
                     /score="352.1"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="VERHARLTPERTAVVCEDRVLTYGELNSRANRLARRLRDEFGVTP
                     GKMVGYAVERSERVPVIQLAVLKAGGAFLGIDPAHPEARSRAVLEDARPVLLVVDGHEQ
                     GCRPEGVEWLPVLALDDAPELSDDGEGAADLTPAAGPDDPAYVIYTSGSTGTPKGVMVE
                     HRNALALLWAGGWPFDFRDDDVWTSTHSFAFDFSVWELHLPLSRGARVVIIPEATRRDP
                     RKLLPVLVRERVTVLSQVPSTFERAVDALDRRPELAPTSLRYVIFGGEPINPGAVRRFA
                     GHLPGVDLVNGYGITETTVFTTFKRLDLSEAPEAADAPPSDMQNIGRPIGTMSVELRDM
                     DGKLVPEGSVGEIVISGPAVARGYLGRPEETARVFGVHADDPGAGGHDGRPPRRWYRSG
                     DLARRLPSGDLVFVGRRDRQVKIR"
     CDS_motif       23934..23975
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0010"
                     /evalue="5.70E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1325"
                     /protein_start="1311"
                     /score="10.4"
                     /tool="antismash"
                     /translation="LAVLKAGGAFLGID"
     CDS_motif       24177..24236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0011"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1412"
                     /protein_start="1392"
                     /score="35.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVMVEH"
     CDS_motif       24780..24869
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0012"
                     /evalue="6.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1623"
                     /protein_start="1593"
                     /score="44.1"
                     /tool="antismash"
                     /translation="PEGSVGEIVISGPAVARGYLGRPEETARVF"
     CDS_motif       24978..25040
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0013"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1680"
                     /protein_start="1659"
                     /score="30.0"
                     /tool="antismash"
                     /translation="FVGRRDRQVKIRGYRVELEEV"
     CDS_motif       25122..25190
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0014"
                     /evalue="1.30E+00"
                     /label="C2_dual_024-063"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1730"
                     /protein_start="1707"
                     /score="1.7"
                     /tool="antismash"
                     /translation="MVAYLDDRDRERIPALRQRLQEL"
     aSDomain        25377..25577
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03780_PCP.2"
                     /evalue="3.40E-18"
                     /label="HEP86_RS03780_PCP.2"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1859"
                     /protein_start="1792"
                     /score="57.6"
                     /tool="antismash"
                     /translation="SLGELWGELLGHCDLGPDDNFFTVGGHSLLAVALVTRVEENLGVV
                     LGLEDVLTHATLAGQAELIDAR"
     aSDomain        25644..26543
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03780_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.00E-54"
                     /label="HEP86_RS03780_Condensation_LCL.2"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="2181"
                     /protein_start="1881"
                     /score="175.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVWDG"
                     /tool="antismash"
                     /translation="DHPLSPAQSEFWLLDQFRAPGTPAATPEILELGTPWDPAADRAAF
                     ARLVESFEILRTDFPLADTHPRQRIHPHGHEDALRLTDLSRSPTAEDLRNLLDEEAARP
                     LDLTEGPLFRLHLVRRPDTSTLAVVTAHHIVWDGMSCDVLTRWWQQDRQAQRAGDVTPR
                     RPARQFRDIAAQQLDYLRSPEGRAELAWWTGRLTGAHRTRPDLTPLGIGYPSGPRDFLG
                     CRHRVTVDAGRTRALQALCSDARTTLFAGLHAVVKAFLFALTRQTDLVVMSPVSLRDGR
                     VLEEQLGPLINTVALRDHV"
     CDS_motif       25731..25823
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0015"
                     /evalue="6.70E-03"
                     /label="C2_DCL_024-062"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="1941"
                     /protein_start="1910"
                     /score="8.8"
                     /tool="antismash"
                     /translation="LELGTPWDPAADRAAFARLVESFEILRTDFP"
     CDS_motif       26037..26081
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0016"
                     /evalue="3.10E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="2027"
                     /protein_start="2012"
                     /score="13.5"
                     /tool="antismash"
                     /translation="HHIVWDGMSCDVLTR"
     CDS_motif       26445..26534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0017"
                     /evalue="5.50E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="2178"
                     /protein_start="2148"
                     /score="15.7"
                     /tool="antismash"
                     /translation="DLVVMSPVSLRDGRVLEEQLGPLINTVALR"
     CDS_motif       26598..26675
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03780_0018"
                     /evalue="5.10E-01"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="HEP86_RS03780"
                     /protein_end="2225"
                     /protein_start="2199"
                     /score="3.1"
                     /tool="antismash"
                     /translation="DALAHRRIPPGDIGRALGLDADAPLA"
     gene            27023..27754
                     /locus_tag="HEP86_RS03785"
                     /old_locus_tag="HEP86_03785"
     CDS             27023..27754
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012571.4"
                     /locus_tag="HEP86_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03785"
                     /product="phenylalanine 4-monooxygenase"
                     /protein_id="WP_168477281.1"
                     /transl_table=11
                     /translation="MDTQEILSVQHHHEPADHEVWRHLYRQQLDLVPLAAPAIYLEGLD
                     LLGLPADHVPDLDRVNERSRAITGWTFVAVDGLVKGADFFTMLLNRRFPVTNQMRKPEE
                     IRFAELPDLFHDLFGHGPFLAHPRTADLYQEFGRIGVRCAERPDELALLQSIMWTTLEA
                     GLIRTPDGLRALGGAILSSADEIQQCLDPAAATETFDPEVVRRATFDILQLQNRYFVIE
                     DLAEIESALADLDARVDEGDR"
     gene            27754..29409
                     /locus_tag="HEP86_RS03790"
                     /old_locus_tag="HEP86_03790"
     CDS             27754..29409
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037824.4"
                     /locus_tag="HEP86_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03790"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_168477283.1"
                     /transl_table=11
                     /translation="MTKPQTTTGYFLRGDVEVEPLVDRWYAWVHLVSPATAAFVTMERH
                     LRMMESYVRSPAMHAAAAANPATRSGPFLDLGGAKVAEVQALLDATRTKAKRQQDFVAA
                     FGELDTLLESMTGGALEPLYPSVPAALQGLVELEYDRHNRARCRLYERLLYADALADPS
                     GQCLRLVRTDRDGDRPFAFSTPRLPVVEDPDDTDGAAWEGAVELDLPFATPALDTLFRA
                     RTEPVDPDELADELGLDAGARARFRELFTTTPPRTPDERADSRPGPGQVRVTYFGHACV
                     LVEDDEVSILVDPVLPYDHESDVPRRSFADLPDRIDYVLITHAHHDHVLPETLLQIRHK
                     VGTVIVPGNDGGGLMDPSLRLVVEHLGFPDVREVRELDVTHLPNGAITAIPFVGEHHDL
                     AIRSKSTYHVRLGGLTALFGADTANVNPALYDRVHDLVGDVDLMFLGMECEGAPASWVY
                     APYFAHPLDRDHDQSRRGRASTCDEALDVVERFRSSAVYVYAMGEEPWLYPLLGIPYTD
                     ESLAIREAKRLVETCHEQGRHSERLYGAKRWSVS"
     gene            29406..33344
                     /locus_tag="HEP86_RS03795"
                     /old_locus_tag="HEP86_03795"
     CDS             29406..33344
                     /NRPS_PKS="Domain: AMP-binding (263-661). E-value: 3.5e-84.
                     Score: 274.7. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03795_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (772-840). E-value: 5.8e-18. Score:
                     56.9. Matches aSDomain: nrpspksdomains_HEP86_RS03795_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (869-1170). E-value:
                     6.3e-42. Score: 135.7. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03795_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="HEP86_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03795"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_168477284.1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-94, bitscore:
                     315.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-11, bitscore:
                     42.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-33, bitscore:
                     115.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISRIEALQGPAHQQQRAAWLTAMPSPEDALHWADSVVTANTAA
                     PGTRHRVTLGPESRRRVTAVSGGQTLGDFVVLLSALVAVVQRTSAHDVVWLSTPLLHGV
                     DSPYGYDDRVPLVFRPERRGSFKSLLEHVRHQVATSYAVQGFPVRDLWAQADGPTDTGV
                     VVAETSLHEDVAVDDSTELVIRINTAEGSFDVEDRHGRFPEWFADHVVGLVEKVLEYLD
                     DTGVAVADLDLLDDDEILHQLDTLTATGVPAHTPDDSLATRFRAVAAADPDATALLTGG
                     RAVSYGELHSRAAQFAHHLRDDLSLAEGEAVAVLVSRAEDTLVALWGCMLAGTAYVPID
                     PHAPTDRIAQIADAAKAKVLALHSSLLHRLTDLPTLTVCGLDLQFPAGTAAVSPAEPTW
                     PAPRGGDAAAVITTSGSGGTPRTIVLDHAGVVNVALDHVTELGLGPSDRYLAFMALSFD
                     GALLDIVMTHLAGAALVLPDEQELADPRRLEDLMAGHAVTATTMTPSYLSALDPLRLTD
                     LRVLISAAEPANTADLLAYAARGVSVYNGYGPTEACVNTTLHQVDPQRDYHGVPLGRPR
                     ANMQVYILDQDRNLLPRHVIGEIAISGRGVASGYIGDPEQSARRFVPHPFRPDGGVLHL
                     SGDLGGWDENGELVFAGRRDQQVKIRGFRVEPTEIENALRTHDRVEDAVVAADTDRGVL
                     VAFVREPGGHGPEHGAVPVDALSDHLARTLPAYMVPSAVHLVDNFPTTEHGKVDRRALL
                     DLHERRLAERPVSTPANPLETRLLEGWVKVLGLPAIDAEDDFFQLGGDSIRLIQAVQAA
                     EQVGITLRTSDIIEQRTVRALAGMVAERGDATESVTPAVSASVSLTDDETRQLPARCED
                     AYPLTHLQERMVEWSAEPDLRALHAYHCVAGWRLRDGELDLDVLRQALRGLVERHRSLR
                     TAIVRAAGSGRLLQCVLPPDATLVDTVEAHPEDTADTVLNAVVEADLAEAFDTDGAAPW
                     TRFHLVVRSATEVDVVMSAHHALTDGWSGVQLRNELLDDYGTLRAGGRPDTAAPTVDSY
                     REFVALERTLADDPQAQGFWADALATLPDGLTTPRRREFRRVGYTEVVVPPERVEALLA
                     GTRNKGLSPKARCLSAFLAALHRHGGAPELTVGIVANGRSERLTDPLGTTGLFWNILPV
                     NSRWDADTQPPSATAVQARLEALEPYAGYPLAGHVADDEAIAGWFNFVHFHHARQAVDR
                     LTLVEECIALGQLHHPVVLAVSLEPATPGGAPQLVATLEHDLDRLDEASAERLMALWSE
                     ALSSPATDTPGYDAVPGIPEESRDTVQS"
     aSDomain        30195..31388
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03795_AMP-binding.1"
                     /evalue="3.50E-84"
                     /label="HEP86_RS03795_AMP-binding.1"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="661"
                     /protein_start="263"
                     /score="274.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FRAVAAADPDATALLTGGRAVSYGELHSRAAQFAHHLRDDLSLAE
                     GEAVAVLVSRAEDTLVALWGCMLAGTAYVPIDPHAPTDRIAQIADAAKAKVLALHSSLL
                     HRLTDLPTLTVCGLDLQFPAGTAAVSPAEPTWPAPRGGDAAAVITTSGSGGTPRTIVLD
                     HAGVVNVALDHVTELGLGPSDRYLAFMALSFDGALLDIVMTHLAGAALVLPDEQELADP
                     RRLEDLMAGHAVTATTMTPSYLSALDPLRLTDLRVLISAAEPANTADLLAYAARGVSVY
                     NGYGPTEACVNTTLHQVDPQRDYHGVPLGRPRANMQVYILDQDRNLLPRHVIGEIAISG
                     RGVASGYIGDPEQSARRFVPHPFRPDGGVLHLSGDLGGWDENGELVFAGRRDQQVKIR"
     aSModule        30195..31925
                     /complete
                     /domains="nrpspksdomains_HEP86_RS03795_AMP-binding.1"
                     /domains="nrpspksdomains_HEP86_RS03795_PCP.1"
                     /locus_tags="HEP86_RS03795"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       30384..30425
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03795_0001"
                     /evalue="6.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="340"
                     /protein_start="326"
                     /score="13.2"
                     /tool="antismash"
                     /translation="WGCMLAGTAYVPID"
     CDS_motif       30627..30686
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03795_0002"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a3"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="427"
                     /protein_start="407"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AAVITTSGSGGTPRTIVLDH"
     CDS_motif       31179..31268
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03795_0003"
                     /evalue="3.40E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="621"
                     /protein_start="591"
                     /score="35.4"
                     /tool="antismash"
                     /translation="PRHVIGEIAISGRGVASGYIGDPEQSARRF"
     CDS_motif       31353..31418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03795_0004"
                     /evalue="6.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="671"
                     /protein_start="649"
                     /score="34.2"
                     /tool="antismash"
                     /translation="FAGRRDQQVKIRGFRVEPTEIE"
     aSDomain        31722..31925
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03795_PCP.1"
                     /evalue="5.80E-18"
                     /label="HEP86_RS03795_PCP.1"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="840"
                     /protein_start="772"
                     /score="56.9"
                     /tool="antismash"
                     /translation="ETRLLEGWVKVLGLPAIDAEDDFFQLGGDSIRLIQAVQAAEQVGI
                     TLRTSDIIEQRTVRALAGMVAER"
     aSDomain        32013..32915
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03795_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="6.30E-42"
                     /label="HEP86_RS03795_Condensation_DCL.1"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="1170"
                     /protein_start="869"
                     /score="135.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHALTDG"
                     /tool="antismash"
                     /translation="EDAYPLTHLQERMVEWSAEPDLRALHAYHCVAGWRLRDGELDLDV
                     LRQALRGLVERHRSLRTAIVRAAGSGRLLQCVLPPDATLVDTVEAHPEDTADTVLNAVV
                     EADLAEAFDTDGAAPWTRFHLVVRSATEVDVVMSAHHALTDGWSGVQLRNELLDDYGTL
                     RAGGRPDTAAPTVDSYREFVALERTLADDPQAQGFWADALATLPDGLTTPRRREFRRVG
                     YTEVVVPPERVEALLAGTRNKGLSPKARCLSAFLAALHRHGGAPELTVGIVANGRSERL
                     TDPLGTTGLFWNILPVNSRW"
     CDS_motif       32088..32207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03795_0005"
                     /evalue="9.10E-11"
                     /label="C2_DCL_024-062"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="934"
                     /protein_start="894"
                     /score="34.0"
                     /tool="antismash"
                     /translation="HAYHCVAGWRLRDGELDLDVLRQALRGLVERHRSLRTAIV"
     CDS_motif       32430..32483
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HEP86_RS03795_0006"
                     /evalue="2.90E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="HEP86_RS03795"
                     /protein_end="1026"
                     /protein_start="1008"
                     /score="13.6"
                     /tool="antismash"
                     /translation="HHALTDGWSGVQLRNELL"
     gene            33325..35103
                     /locus_tag="HEP86_RS03800"
                     /old_locus_tag="HEP86_03800"
     CDS             33325..35103
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     conventional flavin-dependent halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="HEP86_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03800"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_168477286.1"
                     /sec_met_domain="Trp_halogenase (E-value: 0.0001, bitscore:
                     20.1, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLFSPEHSATPDETPWYDVVVCGGGLAGATFARQLRREQPDASV
                     LVIDGQTYPVPLAAHKVGESTVDIAGFYFSSVLGLAEYMADKHLPKLGLRYFFGQAGRP
                     FAEAPEIGLSGFPGRSTYQIDRGVLENDLYEMNCEAGVEIATGSMVREVDLGPGEDSHL
                     VQYVDGEGVPRSARCRWVVDAMGRARYIQRKLGLQRPTEGQFNAVWFRVAGRLDVEDFV
                     SDDNTDWHERVPGRNRRLSTVHLMGPGYWVWLIPLGSGNTSVGIVTSGEIHDIDGMSTL
                     PTAVEWLEKNEPAVASALPHHEVLDFLAVRDYSYTSSQVFSADRWGCLGEAAAFADPFY
                     SPGSNMIAFENSGLIGLIGEDARGALRPERVDELSRFMLSQNDWLTYNIHSSYSYFGEP
                     LIMALSFIWDTLLSWTTATPQIYNGIFLDEEKAAAVRTATPGLYALTVQVKRLFKQWEQ
                     KAGRGRDFRFIDYDKIPFLHEAYERNLVEGKSVADLVADHRHSMAVLEEVAQAIFLIAV
                     EDTMPERRAQFGEHPWLNAWAIGLDPEHWRSAGLFQPTTPPRSLDETYATLTALFDAPS
                     PEPDTTPAALPIELRL"
     gene            35279..36409
                     /locus_tag="HEP86_RS03805"
                     /old_locus_tag="HEP86_03805"
     CDS             35279..36409
                     /NRPS_PKS="Domain: Aminotran_1_2 (50-354). E-value:
                     3.4e-36. Score: 117.0. Matches aSDomain:
                     nrpspksdomains_HEP86_RS03805_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="HEP86_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03805"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_168477288.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.5e-34, bitscore:
                     117.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISTCRQWHELSLIERQARAARHDGQPTWDLSEALLRGLPASAGR
                     VDFRAETYPDPQGERELRRRIAARENAKYGLSLTEDHIVVTHGATEALFLLAHTFLNPG
                     DRVAVQAPSFLFYREILENLGATVVPLNAEPDSARPARMRLLHSPSNPDGRVLAEGTLS
                     LHAEAARADGSLLVLDQVYDELIVSGTRPREDQAVLDSGHVVKVNSVSKAFGCPGVRIG
                     WITTAPAVAEVLTGVAERLRMGPSLVAQQAATALLVRPVDGNLELLAERRAIALDALST
                     LDLFEEAAPPPGGLFLWLKLADPNASAQQFCDRALAEVGVRLMPGLGFWQGTDDRVRLS
                     FGAVPDYLDAAFDRLRQLTVPSRRSAAGLTTAHGIR"
     aSDomain        35429..36340
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HEP86_RS03805_Aminotran_1_2.1"
                     /evalue="3.40E-36"
                     /label="HEP86_RS03805_Aminotran_1_2.1"
                     /locus_tag="HEP86_RS03805"
                     /protein_end="354"
                     /protein_start="50"
                     /score="117.0"
                     /tool="antismash"
                     /translation="ETYPDPQGERELRRRIAARENAKYGLSLTEDHIVVTHGATEALFL
                     LAHTFLNPGDRVAVQAPSFLFYREILENLGATVVPLNAEPDSARPARMRLLHSPSNPDG
                     RVLAEGTLSLHAEAARADGSLLVLDQVYDELIVSGTRPREDQAVLDSGHVVKVNSVSKA
                     FGCPGVRIGWITTAPAVAEVLTGVAERLRMGPSLVAQQAATALLVRPVDGNLELLAERR
                     AIALDALSTLDLFEEAAPPPGGLFLWLKLADPNASAQQFCDRALAEVGVRLMPGLGFWQ
                     GTDDRVRLSFGAVPDYLDAAFDR"
     misc_feature    35711..35713
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    36450..36464
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            36547..37875
                     /locus_tag="HEP86_RS03810"
                     /old_locus_tag="HEP86_03810"
     CDS             36547..37875
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="HEP86_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03810"
                     /product="MFS transporter"
                     /protein_id="WP_168477290.1"
                     /transl_table=11
                     /translation="MTMPSATQSPPREGLRRNRDFHIFWIGETISLFGAEVSLLALPLT
                     ALVVLGADAADLGLLRFVEYLPFLALALPLGVLVDRSRRHPLLVIANSARAVLVGIIPV
                     LAALGWLSMSWLVILALGIGTFTVLFDLCLPAYLPKFVASEDLLSANGRVSMSQAAAEV
                     AGPGLFGLLVQWLTAPLCLALNAGSYLVSVLSLLLIKRPEPAPTRVVGTPWQDLYDGLR
                     FLVRSRLMRAVTLAGSLYNLAWAIFQTAFLVYMNKILGFNVGIVLAVGAAGGLAGAACA
                     PWLSRRLPVGVTYLAAAAAIAVPALLIPAVTGQRTTLALVDTALLVLMNGGLAVFSVLT
                     ATLRQSVTPDGLMGRVVAGYRALVFGGISLGGLITAWLGNLAGPRAILWVAGVFFLSAL
                     APVLLSPVPRLRGFGTADSPLSGTESAAGERAEASSDHTEAGS"
     gene            complement(37930..39780)
                     /locus_tag="HEP86_RS03815"
                     /old_locus_tag="HEP86_03815"
     CDS             complement(37930..39780)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542846.1"
                     /locus_tag="HEP86_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03815"
                     /product="beta-galactosidase family protein"
                     /protein_id="WP_168477292.1"
                     /transl_table=11
                     /translation="MTQFSRRRFVSAAVVGAASVGVALGGGRTTLAQADSPRGLTVRGS
                     EFLLDGEPFRILSGAFHYFRTHPKDWRDRLLRMRAMGLNTVETYVAWNFHQPHEGKTDF
                     TGWRDVVSFVRIADEVGLKVIVRPGPYICAEWDFGGLPAWLLKDKDAPLRRSDPAYERA
                     VDAWFAELLPRFVDLQATRGGPIIAMQVENEYGSYGDDHAHLEHLRDTMRAQGVDSLLF
                     CSNGASQEMLRNGSLPDLLSTVNFAGDPAGPFAELRKFQPDKPLFCTEFWDGWFDHWGE
                     PHHTTDPAQTAADVQKLLESGASINFYMAVGGSNFGWYAGANLTGSHYQPTVTSYDYDS
                     PISESGELTEKFHQVRDVLAKYSTLPSTPLPATPRRMPAQRVAVRESVPLMDALDALST
                     PIRRTAPAHMEAVGQSYGLIHYRTRVRGPQGTKSLRLTGLGDRALVFGDGKRIGTFDRN
                     QPDHTVDFTVAGASGTLDLLVDPTGRINFGEGLNDPKGLSGKVLLGEDELSDWEIRRLP
                     LDDLSAVKFGSGDVPTGPAFHRARVHVDTPADGFLAFPGWDKGMVWLNGFALGRYWSLG
                     AQVTLYAPSHLWRRGRNELVVLEMERTGDRIEVRSEPDIG"
     gene            40112..41173
                     /locus_tag="HEP86_RS03820"
                     /old_locus_tag="HEP86_03820"
     CDS             40112..41173
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0032958 - inositol phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015712.4"
                     /locus_tag="HEP86_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03820"
                     /product="inositol polyphosphate kinase family protein"
                     /protein_id="WP_168477294.1"
                     /transl_table=11
                     /translation="MHSHGDRRAIADDSRRRQATARPTTKKARPTTDAGAGADPATVLA
                     LQRTAGNAAVTRLLEDGRPRDGATGQETVQRAVHGGTPGEVVQHAEEEATGGHGGIKDR
                     VGGKIKEKPTNDVERGFYADMRAGKHPALEGVVPDSYTAEQVQTMDGEKGKGDDSTHIY
                     IDNLTHDMKMPKVLDIKVGESTASKQELLTSMSKADAWKKKMKLKVADKVTGSADRGYR
                     AVGGTGLKGKSRRAIGRESEQIVQGISADPSVYDLLVEQLTQVRTAAENSGLAFIAASV
                     LIAVDEQPATESPAATAKLNLIDFAHTFGPEQLSEEQVKKYRTRFDKGMARLIADVKAA
                     GAAKKEAGEEADA"
     gene            complement(41534..41833)
                     /locus_tag="HEP86_RS03825"
                     /old_locus_tag="HEP86_03825"
     CDS             complement(41534..41833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848646.1"
                     /locus_tag="HEP86_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03825"
                     /product="DUF6342 family protein"
                     /protein_id="WP_085923051.1"
                     /transl_table=11
                     /translation="MADIDLGLATDWTEGDTHGRIKLRQNQVYPTSPKKDVLISSPVSI
                     ELSVNTNCSTSQEADKIYFTTHHGSTKKIIAVLDSDGNLHIAGRLITDQKDLSY"
     misc_feature    complement(42130..42145)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.24"
                     /tool="antismash"
     gene            42191..43615
                     /locus_tag="HEP86_RS03830"
                     /old_locus_tag="HEP86_03830"
     CDS             42191..43615
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_03830"
                     /product="hypothetical protein"
                     /protein_id="WP_168477295.1"
                     /transl_table=11
                     /translation="MLETLWTVIVPALVLMGCTLVLTELVWVLVTLRRVDPEDRWLDRV
                     AGRSRVRVLAERTFHLVLWVHAHTVGPAVRRYVRWGARGTTRHLRWARRGFGQDAERLF
                     PRSHAVRTAVWDWYCTMPLAGIAYVIKACVLLLVTVNIGAIVTKLVTGVTHLWEKSKRA
                     PGGSAANPVVEGGGSERSDPLLALMAALRRVGAAIADKVGHHLSALTDPLGRPMEAIIA
                     AAALVLLAMMLLASRVAWLALRQIARPSYQDHGPHYAEPRTRFTWARRLLSLRVGTNRE
                     NRPVVVLVNCLARVGAAQSYHRWSLRIRSPLTAPRVQLADAERVVWSAWRTRHTAIRGV
                     LRAQHKEHAAEVVGALRMMETRQDTDADRGQAFEDMARMLAKIAERYAQGRTLALLDPE
                     DLTGASRAVNREWIRMVILGVAVIGSAVGASALGVSDAALAQVVGIVSLIMVGLLYGSR
                     LTPTDLLDVVRGQSRK"
     gene            complement(43706..44722)
                     /locus_tag="HEP86_RS40290"
     CDS             complement(43706..44722)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024753.4"
                     /locus_tag="HEP86_RS40290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_248000998.1"
                     /transl_table=11
                     /translation="MRAAPLGSAEGSPEPLWSPIQDVADAASPAPLPVRDVVVYAASGG
                     GIAARRVTDGRERWRADEAKAEAGYLSIGDRLVAAADAEGTLRTWVAATGSPRWTVDAE
                     VGALLAADAHAVYLLTSDGRLRCVGTDGKVRWTRRPPLTLSGGHPAAALGAGHLVLCTE
                     TGDVAAVRADDGSRAWIRKGQAAGPLRPAIDGGTVYLGGNSLAAVKATDGHELWAQNPL
                     RPPTRGTGGWGPPTVAGGVIHALDCDALHSLHANGSQAADPMMVAGVVPPWQPPVVQGN
                     SVWIVESGDTGVSGLPRGGEGRPQTYALTGGQSRSLAAAANRLFVLNRSTLLALPVY"
     gene            complement(<45078..45722)
                     /locus_tag="HEP86_RS40295"
                     /pseudo=""
     CDS             complement(<45078..45722)
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="HEP86_RS40295"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /pseudo=""
                     /sec_met_domain="Pkinase (E-value: 5e-29, bitscore: 100.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 6.9e-07, bitscore: 28.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKVYFGADATGSPAAVKVLLPELAHDGHLAERFLREARTAQAVT
                     SEGVARVLAAELESGRPWIATEFLAGPTLDDAVARFGPLDDAAVRELARSLARTLQDVH
                     ATGLVHRDVKPPNVVLTSRGPRLIDFGIARPEHGLTLTRTGQIPVTPGYGAPEQVLGQR
                     VGPAADVFSLGAVLAYAASGRPPYTGAEVTAVLYEVVHGSPDLSAVPEALRY"
     gene            complement(45859..48039)
                     /locus_tag="HEP86_RS03840"
                     /old_locus_tag="HEP86_03840"
     CDS             complement(45859..48039)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019334.4"
                     /locus_tag="HEP86_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03840"
                     /product="protein kinase"
                     /protein_id="WP_168477297.1"
                     /sec_met_domain="Pkinase (E-value: 3.2e-36, bitscore:
                     123.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPLLHDDPHAVGPFRILARLGGGGMGTVYLARSAGGRTVAVKT
                     LHTRLAADTTLRTRFRLEADAARVIGSAHGAVVVDADPQAPTPWLATEYVLGPPLDTAV
                     EAGGPLPEAAVRALGAALAAGLEQLHRSEVVHRDLKPSNVLVTAQGPRIIDFGIARAFG
                     DEHLTSVGGAVGTPAFMSPEQAGGQEHAVAGDVFALAGVLVFAATGRGPFGGGAPTDLL
                     YRVRFGEPDLGGVPETLRPLLVRCLAKDPAHRPSTTELRTALGSNGLAPADRGGFAELL
                     PDAVLREISRRSDEVWREPPHRLPPPAPAEVPPAGAAPAPGLSRRRLLSVAGGALMGGG
                     LLGGGGWALLAGSGEGGGATKKDAVDRPKPPTPLWSAGLRCPDSGGEVMRVGRNLAMRA
                     GIVLCGINAESGESTWQANVSDPWRSVTEGSRIYALRGYKEAGAALAVCEVSQSNGELG
                     KPLVELSAFTGKEQYNQLLCVADGTAYLVARAASGRRWYLVAADLDSGKERWRSPVEGP
                     QTVGTPPALGGAVVGSRVVLCGSPGFGSKFIRLSVHDTRHGRELWRLSETFAGTVPPQL
                     VLDDRNLYIGAEHLTARRLSDGELAWLFGTGRDVGDSAGEERRYGAPTVHDGVVYCTEA
                     DRGLIAVDAASGTLNWQEKGLSGRKNKRDVAPAVGKRYAYCADDKGLRAIDLRTHQAVW
                     TYETNPMVLTADPKGGRLYVRQEQRTIALPLA"
     gene            complement(48044..48871)
                     /locus_tag="HEP86_RS03845"
                     /old_locus_tag="HEP86_03845"
     CDS             complement(48044..48871)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576401.1"
                     /locus_tag="HEP86_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03845"
                     /product="serine/threonine protein kinase"
                     /protein_id="WP_248001563.1"
                     /transl_table=11
                     /translation="MALARLDAEGSRGVPERRYLARSVDGGHTVLVCLPPAGGDPARWA
                     DEMQQAARLTQPGFWPVTQLGGTPAFPWYASPYRPVLPLPAALAAYGGPLPEPLVRMLG
                     GTLAEALASAHVLGLVHGGICPAGVLLTACGPLLGCFGATRAHPVAVASPAQATGLETG
                     CLAPELAAGGAADRAADIYALGAVLAYAATGHTVPERQEIPAGLRDIVTACRSRAPEDR
                     PEPARVLAELLPGAAYGALAGATEPVSLPGRIVEALSRQSAEVLATALPTQER"
     gene            complement(49089..49508)
                     /locus_tag="HEP86_RS03850"
                     /old_locus_tag="HEP86_03850"
     CDS             complement(49089..49508)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="HEP86_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03850"
                     /product="ABC transporter permease"
                     /protein_id="WP_248000999.1"
                     /transl_table=11
                     /translation="MPTFLVIALIAGARFPGGVVGIGVTVLAAVLPALIFSALSNAVAL
                     LTRQQATLIAISQFTTLPLMFLSSAVMDLHLAPSWVGRVAACNPVEWAVAAARQAMLVH
                     ADWSMVWARLGLLAAAVLVRGFLATRAFRAYRKST"
     gene            complement(49607..49999)
                     /locus_tag="HEP86_RS03855"
                     /old_locus_tag="HEP86_03855"
     CDS             complement(49607..49999)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_03855"
                     /product="hypothetical protein"
                     /protein_id="WP_168477301.1"
                     /transl_table=11
                     /translation="MRAVKKSMTIAAMACLTLMGTVAAAPTASASSGNYIQFSNNSGFL
                     VDTCYQWKGPDGIESKNYCHTSKPVGQTWKAYFPEEATGATATVTFAMGNGGAKEYLYD
                     LSADKNHCYQTTGLWPNGGEVLGTNC"
     misc_feature    50002..50016
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.67"
                     /tool="antismash"
     gene            complement(50043..50405)
                     /locus_tag="HEP86_RS03860"
                     /old_locus_tag="HEP86_03860"
     CDS             complement(50043..50405)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_03860"
                     /product="hypothetical protein"
                     /protein_id="WP_168477303.1"
                     /transl_table=11
                     /translation="MAYGVATLLLALGGTAVTASPAAAQDSGHIGFSNKGWFLAKTCYK
                     WQGSATPDSCDDNKAIGQDWGVDIPADATGVEVTVLVHGQQIGDLEAPQITDLKSNHCY
                     ELSGYTWGPSINEKSC"
     misc_feature    complement(50437..50451)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     gene            complement(50455..51144)
                     /locus_tag="HEP86_RS03865"
                     /old_locus_tag="HEP86_03865"
     CDS             complement(50455..51144)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_03865"
                     /product="hypothetical protein"
                     /protein_id="WP_168477305.1"
                     /transl_table=11
                     /translation="MTFRYRAGIAAAASAMALAVAVPTASAASPQEINGHTDNWLNEGS
                     ATVKYDNGTTLTRQADVLEALQQCGNLSVSCASTTTQDAGQVTKWYDAENQDLGTGPID
                     NCAPNGNDITQTITALHTFSWGWNIGASVDVTLVKDRLGIGASAGFTQSHTETSSGAVG
                     ITVKPGQKGMLKMGYDMDRKVTDVSIQGGKFGGAKITGLRTETPGQGGKRVGQDIVTCD
                     QKLLNGR"
     gene            complement(51218..51592)
                     /locus_tag="HEP86_RS03870"
                     /old_locus_tag="HEP86_03870"
     CDS             complement(51218..51592)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HEP86_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HEP86_03870"
                     /product="hypothetical protein"
                     /protein_id="WP_168477307.1"
                     /transl_table=11
                     /translation="MKRRSKVLFGLATVAGACLPLGAFATTASAAEGTHIQIKQNAAIA
                     ATTCYTFVGAEDKNYCNISRPMGDSLSVGVPANTTQVVIDLKNFPWESPSDSIAVTPDK
                     NRCVEVSGTAFNSKLLEVGC"
     misc_feature    51603..51617
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.73"
                     /tool="antismash"
     misc_feature    complement(51604..51617)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.98"
                     /tool="antismash"
     gene            complement(51856..52746)
                     /locus_tag="HEP86_RS03875"
                     /old_locus_tag="HEP86_03875"
     CDS             complement(51856..52746)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="HEP86_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HEP86_03875"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_168477308.1"
                     /transl_table=11
                     /translation="MNTLCLRRLQIFVAVVECGGFSAAARKLYMSQPSVSNQVRRLEAS
                     LQATLIDRSGARIRLTAKGETFLSYAQRLMPLVEEALIAVQLTVSSSEPRLRVATTNDA
                     AAILVPSVLARLTARIPGLRWDIHTGGMEQVTQQLIDGVVGMALLDGEPTAPGLVIEPI
                     LSERLVLVVGGEHPLAGRQVTAEDVATKRLLLRESGSATRDLQNTALRRWNIQPVDKGE
                     VWGNEALKLAVSAGLGASLMSWHCVAQEVRDGRLALVDLVPALPSHPIVMAHLLGRKFS
                     CVEEAFAQLLFDLKE"
     misc_feature    complement(53060..53074)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.1"
                     /tool="antismash"
ORIGIN
        1 gcacgccctt ccggactgct ggagatgcgc agcggtccgg cctcttcctc ggaggagtcg
       61 cacgggctga ggaccgtgcc gccgtagtcc gtcagataca ggcgcaccga agtggccccg
      121 taggcggtgg cgaggtgatc acgcacggtg tcgagcaggg cgtgtggtgc cgacgcgcgc
      181 agcgcccggc ccacatcaat gccatccgtc atgcttgcgc ggaccccctt cgtgcggcgc
      241 caagggcagg gtcggtctga caacaggacg cacagggtga cagagtgttc gtgtgtcccg
      301 tttcaccagt cggtcccctt cccgcgagca agcgagcgcg gcggcccttg ccgcctccga
      361 gctgctcgag gttctgtggg gacgcggaca ggaagcggcg cgctcggcgg aggtctcccc
      421 gtcccagctc cgcgcactcc tcgtgctcga aaagcgggaa ggcacgaacc tgcgcaccct
      481 ggccgaagcg ctcgcctcgc ggccgccggc ggtcagccgg ctctgcgacc gcctggaggc
      541 gatgggcctc gccgaacgga gccccagcgc gacgagccgg cgcgaggtcg agctgaggct
      601 gagcttgcgc ggcagagtgc tgctggagga gtaccgcgcg gcacggagcc gagacgtcac
      661 ggccaccctg gagcagatgg aacccgccga tgtcgccaag ctcgcggccg gcctggaggc
      721 cttccacgcg gcgttcgccc ggcgcgcggc cgacgagggc ggcccttccg tccgggacga
      781 cagcgtcgcg gacagtgcct gacctcacct gaactccgcc tctcgagccg acatcccccg
      841 ccggaaacgc tctgcgcgga cggaacaaac ggatcttcgc cgccacgggg acgctatcaa
      901 accggccctt caccaccggc cgttcgccac tggccgttcg gtcgaacggg gcgcggtgtg
      961 gtgggcctcg cccaggggct cccgcccgcg cgtcagacgg tcagctccgt ttggggtgcc
     1021 gccgcagtga tgggggtgtg gcggatgtac cactcggtgg cgaagagccg cttccgtgcg
     1081 tccggcggca gggcggcgat cagacccggc agggcgcccc gctccacctc ggagcgatgg
     1141 gccagtacgg cggcgatctt ctgctcgatc caggggccga cgtcgacggt tgcggtgacc
     1201 tgttcgtccg gaacgctgta caccgccttg cgcgtaccga tcacgtctcg cagcgccggc
     1261 acggccgagt gcgggtgcgt ggccaagtag aggacacggg gctgccaggg ggcaccggcg
     1321 tccggataga gctgagcgag tccggccgcc tgggcagcca gcatggtcac ccggtgggtg
     1381 tgtacgtggt ccggatggcc cggcagcccg ccataggcgt cgtgggtgac catgatgtcc
     1441 gggcggaatt cccggatgtg cgtgaccagc cgccccaccg cctcgtcgag cggtgcctcg
     1501 cagaaccgta cgcagcccgg ggccgattgc ggcacccgcg cgtcggcgta gccgagcatc
     1561 cgcggcttgc ccgcgccgag gatccgcagc gcctcggcca actcctcagc gcgatgcgtg
     1621 ccgttggccc aggtcgccgt gacgaccgcg gtacgcgcgc cgtcagccgc gtgacgggcg
     1681 agcgctccgc ccgccgacaa cgactcgtcg tccgggtgcg cgaagaccgc gagcaagctc
     1741 ggcgcgggca tgggaagacc accttccgtg acggccacga cggataccgg ctgacctcat
     1801 cggccgggca tcgagcgtac agccgtcgtc gtcgcgatgg tcgtgttgag gtggagtccg
     1861 aggcgcgacg agaccgcggg tggctgcggc gctgtgtcac ccgacgtacg gccgccggtc
     1921 ggaccttggt gcgtagcccg ggggcggtcc gcgccggacg gtctgccacg atggcgccgt
     1981 gctgtccgaa ctcgctgcgc cggagcccgt caccgcggag ccgccgcact ccctcgcgcc
     2041 ggtcctgctc acccagagct ggctcgatct ggcgttcctg cactgggccg ttgatccggc
     2101 ggaggtggct ccgctgctgc cggccgggac ggttccggac accttcgacg gggccaccta
     2161 cgtcgggctg gtggcgttcc ggatgcatcg ggtcggatgg ttcaagcttc cgggcatccc
     2221 ctacctcggc accttcccgg agacgaatgt ccgtctctac tcggtggacg gcagcggacg
     2281 gcgcggggtg gtcttccggt ccctggacgc ctcccggctg atacccgtgg ccttcgcgcg
     2341 atccgtggtc cggctgccgt atctgtggtc ccggatgtcg gtccggcacg acggcgacac
     2401 cgtcagctac gccagcaccc ggcgctggcc cggtccgcgc ggggcgcact gccggatcac
     2461 cgtgcggaag ggcgctcccg tgacagcgcc caccgcactc gaacactttc tgaccgcgcg
     2521 ctggggcctg caccacacgt ttcacgggca gccgtcgtat ctgcacaacg cccatccgcg
     2581 ctggccgctg caccgggcgg agctgctgca cctcgacgag aacctgatcg cggcggcggg
     2641 cctgtccacg ccgctggggc agccgctcag tgtgctgtac tcccccggtg tcccggtgac
     2701 gttcggccgc cccaccccgg gcgcctgagc ccgtttccct ggctgaaggc acgtgccgct
     2761 acgccgacga cggcggcgtg cggacgccgg cccgggtcgg gccggcgtcc cctgctcacc
     2821 cggtcgccac cgactccgcg gcgccacggc ccaggaggtc gtggaggaga cgggtggcgg
     2881 ggagatcggg gtggaggtag acgtgttcgt tgctctggcc gacggctgcg aggagagcgc
     2941 ggaaggtcgt cttcgcgtcc tcggtccgtc cggcgtgatg ctgggcctgg gcgaggaggc
     3001 ccaggtggag ggggcggcgc aagtaggttc tggagttgcg gagttcggcc agggaagagt
     3061 gcatgagggt gaggccgtcc tcctgtccgc agtgggtccg gccccagcct tccagcacgc
     3121 ccagcatgcc cttccagtag agcagtccgt gttcatccgc caggcggact ccttcggcgc
     3181 cggaggagcg ggccgtacgg gcatcgtctt cccaggccgc cacgaccgcg tccacgtaga
     3241 gggcgaagca gcggtcggag ggcctgctgt cgtactcggt gaggcgcagc aattcgcggc
     3301 ggcgtgccgt ggcggtcgtg cggtcgccca ggagccagcg ggtgaaggtg tcgtaggagc
     3361 ggcaggagac acgggggtcg tgctggaagg tacgggccag ggagtggccc tcgttggcgt
     3421 acccgtccgc catggcgacg ccgtgctcca gttcggcgag cgcctgccgc aactggccgc
     3481 ggacgtggag gacgatgccc tcgccgtagg ccgcgccgag caccgcgacg ggctggccgg
     3541 tcccgtcggc gaggtcccgg agcagatgcg agaactggcg tgaggcgtcg tagcggccgg
     3601 tgacgatata cgccgcgcac agggcccaga gcaccgacgg gtcttcggga gagcgggcgg
     3661 ccgcgctgag ggcccagccg cgggcgaggg cggtctcggc ctcggcgtgg ccgtagcccc
     3721 gggtggtggc gagcacctgg ccgagttgta tgtgcagccg ctggttcagg gacgcggccg
     3781 aggggtcgcc gggcggcagc aggccgacca ggtggaccgc gcggcgcagc caggtctcca
     3841 cctgttcgta ggcgagttgc tgttcggcct gctcggcggc gcgcagcagc aggggaagcg
     3901 tgtcggccgc cggcagtgcg ctcttggcat gccaggcgtg atgggcgatc cgctcgatct
     3961 cctcgtccgc cagctgcccg agtctgcggg tcgatatccc ctcgacgact ctcgcgtgca
     4021 gccgctgccg gtcctcgcgg gcgagctcgt cgatgagcgt ctcctggacc agggcgtggg
     4081 tgaagtggag ccgttccggg tggtggcggt cttcgccgag cagcccggcc cggatcgcca
     4141 actccagtgc cttggtgacc ggttcgtcct cggtggcggt gcgttccagc aggtcggtgt
     4201 cgatctcggt gccgatgacg gcgcacagcc gcagcacgcg cagcaccgta tcggggaggg
     4261 tggcgaagcg ctggtgcagg gcctcgcgga cgcccgtcgg gacacgggtc aggagcacat
     4321 ccaccgcgtc gggccgccgc aggctccgcg cgtcgcccag gagggagagg agctgcatga
     4381 cgaagtacgg gttgccctcg ctgcgccggt gcagcacctc gacgaccctc gcgtcgacac
     4441 cgggcccgac gagggcggcg acggcgtggc gggacaggcc gccgagccgc agggtctcgg
     4501 tccgggggcc gcgcaggacc tcggagagca tgcggcgcag cgtggcgtcg gactcgatct
     4561 cgtactcacg ggcggtcagg acgatgccga gcggatggcc ctggctgcgg gtactcagca
     4621 gtctcaggag gtcgagggag gcggtgtcgg cccagtgcag gtcctccatg agcaggacga
     4681 gcgggcgctg ggcggcgagg gcgagcagaa cttcgcagac cgcgtcgtgg gtgaggaacc
     4741 gggcccggcc ccagtcggat tccggggccg ggccaccggg ccggtcggcg cgctcgggca
     4801 gcagcggggc gagcagggtg ccgaacggtt ccgccgccgc gcggaaggcg tccgggcggg
     4861 tcgtggacag tcgtctgagg atctgggtcc agacccagta cggtggcacg ccctcgccca
     4921 ggaagcagtg gctccagatc acctccaggc cggaggcgtc ctcgtcggca cccttccggc
     4981 ctgcttgggg ggttcccagc cggagtgcga attcaaggag cagccgggtt ttgccgacgc
     5041 cggcggggcc gaggacgccc gcgacgtgac cgtgcccggc gagcgcgctc gccgccgcgg
     5101 cggtcagccg ctgtaactcc tcgctgcggc cggtgaacgg cgactgggcg cccggactgc
     5161 cgcacacggg gcgggaggac tcggtgttgg ggtcgtactc gggggtcttg gcatccggtg
     5221 gcgtgggacg tgggtgctcg tccgcattgg cggtgggtga ttgccagttc ttggagggcg
     5281 gctgccaatt ctcggtgggt gaaggccagt tttcggtggt tgactgccag ctctcggtgg
     5341 tcgagcgcga gttgttgtgg gtcgagcgcg agttttcggt ggctggccgc gtaggcgtgg
     5401 tggtcggcgg cgtggtggtc ggctgtgagt acgcggtgat tgtcgtcggc cggtgtgcgt
     5461 gtcccgggcc cctggcaggc ccgtccgcct gcgtcccggt cgtcccggcc tcctcggctg
     5521 cggagcgctc gtccggagcg gctgttccgc cgccgatccc accgaatgcc tcggccgccg
     5581 tcggccgctc gggctcctgt gccgcacacg gtgggcgctc ctccgccccc tgtgtgcctt
     5641 cgccgtcgtt ctctgtggca cccccgagcg ccgtggccgg cagtgcgggc ccggccggtc
     5701 cggggctacc ggggcgcggc ccggcggcgg gccgggtgag gggtccggtc agggacccgg
     5761 tcacggatcc ggtcatgagc cccgccgtgg gcccgcccgc ccccggctcc tggcgcagga
     5821 tcgcggtccg gacccggcgg agttcggcgg cggtgcccac gccgaactcc tcctccaggt
     5881 ggacgcgggt ccgttcgtac gcttcgagcg cctcggcttg ccgaccgagc cgggacaggg
     5941 ccgtcatcaa gtggccgacc aggcgttcgc gcgccgggtg gaggcgtgcc tcgcggtcga
     6001 ggtccgcggc cacttcctgg gcttctccga gggcgagttg ggcctccgcg caggactcca
     6061 cggcggtgag ccggacgtct tcgagacgcg aactctcgtc gctgagcgga gggtggccgt
     6121 cgaactccgc atagggcgag ccccgccaca gtgacagggc ggccgtgaac cggtcgcgtg
     6181 cggcgcgtgg gtcgcgtcgt tccagcagca gccgcccttc ggcgaccagg cgctcgaagc
     6241 ggcaggcgtc gatctgttcg ggggcgagtt ccaggacgta gccgtgcgcg cggtggcgca
     6301 gcacggtggg gcggtccggc ccggacgccg gctggagtac gcggcgcagg tgggagatat
     6361 ggctctggag cgtggcgacg gactgacgcg ggggttcctc gccccacagc tcctcgatga
     6421 gcagttccgt aggcaccacc cgccccaggc gtatgaggag cagggcgagc agggccctgc
     6481 ggcgtggcgg accgagaggg aggtcatggc cgtcgtggcg cgccgacatg gggcccagaa
     6541 cgctcagtag gaggggggtt tcgtgcggct cggcctcggg ggccgaggtg gggtgcttcg
     6601 gcgtcaggga tgaaggcata tcggtcccaa tcgttctcgc acgcgcgatc gtgccgacgg
     6661 gctagtggcg cagtgcggcc ggtgcccgtc cgaaccggag ccttacacag aggatgaggc
     6721 gttccaagat cttcgtcgcc gccaaggagc gaacggcaag gtacccgcag gaatttcggc
     6781 caggatggcc aaattcctct caggaagtgg caggaatccg gcagcgtccc gaccagggcg
     6841 cggcaagggg gatgccgcag gatgccagtg atcggaaacc accccgaacg ggaggccgtg
     6901 gtcggagccc gcggtgccgg cgccttcgcg gtcacccgct ggacagacct tcaccaaggc
     6961 cgcctcgcaa cggagaagga gtatcggtcg gatgcgtaac ggattgcttg tgaatcccac
     7021 gaacctaggg cgtgtctttt ggatcagccc ggatcaggcc gcggcgcctg gtgcggtgca
     7081 tcgcaaggcg gagcctctgc cgcgtactgg gcgtactcgg gtgaggcgac aacgccgcga
     7141 ggtgccgtgc cagacgtcgc ggccccgggt tgatccgaaa gacacaccct aggtgtcgca
     7201 cggccaccct ccggagtccc gcaagcggct gtggcctgcc tagggttgcg gtcatggacg
     7261 ggcgaggtcg acgacctggg gcaggcgggc cgcgtggacc ccggtggccc ctttggccgt
     7321 gggtcccgcc ggcggcgccg gtcgcgacgg cgacccggcc ggtcaaggta gcgcgtctct
     7381 caggaggcgc acccgcagga agtccacggc cgccctccgg cgtccccctt ggagcaagca
     7441 gatcggccct ccgacgctga cgcgatgtca acaagcgcct cttcagtgcc gattccccat
     7501 gatcgtcggg catgtgatgt gaagggtcca gttccgtgca ctatgcaatt ctcgggccgc
     7561 tccgcctggt cattaatggt gaacctcgac ccattcgatc ccggaactta tcaattatcc
     7621 tcgccactct tctcgtgaag gcgggaagca ttgtcaccgt caacgacctc atcggcgagg
     7681 tatgggctca gccgccccaa cgggcgcgcg acgcgatcta cgtacacatc tccaaactgc
     7741 gccagcaact cggcaacaag tcccaggacg acgtgatatg gagtcaattc ccgggctatc
     7801 tgatgcgtct ccatggtgag cagctggacc tccagttgtt tcatcgccac cggatcgacg
     7861 gccaccgcaa catggtgaat ggtgactaca aggccgcggc ccgcgactgg aaatccgggc
     7921 tctccctctg ccgaggcaca ctgctgggcg gggcctacgc cgggcccatc ctcggcagct
     7981 tcgactcgtg gctggagcag tcacgcacgg actgcatcga gctgaccgca tggtcacagc
     8041 tcagcgcggg cctgtgtcac gaggtgatcg acttcctctc cctgcatctg acgcggtatc
     8101 cgctgaacga gatcctgtac cagcagttga tgctggcgtt cttcttgtcg cgccaccgtg
     8161 cgcaatccct ccggattttc catcgggccc gccagacact cgccggcgaa ctcggtatca
     8221 atcctggcgg ggatctccgg atgatgcagg acatcgtcct gtccgacgac gtcagccggg
     8281 ccaagcgggt cattgcgtcc gccgtggcgt cacgcgtcag cgacctacgg ccttcgggaa
     8341 ctccgacgac cccctccttc tgttgatgag ttcgacaccg gcaatatttt tccggggcca
     8401 ccggccctca gttgagagcg ccgctcagcc tttccgctgc gccggcctcg cgccacagga
     8461 aagagaaacc gtggtcacct ttcccctccg caccattccg gcggcaccat gaacgccccg
     8521 gacgccagct cgatgctgct cgccctcgcc gtactcgtcc tcgtctgcca ggggatggca
     8581 gccctcgcac gccgcctggg ccagccctcg gtggtcgggg agatcgtcgg cggtgtgctc
     8641 ctcggcccca ccctcttcgg aggccggctc accgacacgc tcttcccaac cgacatccgt
     8701 ccactgctcg gcgcgttcgc gaatgtcggc gtggcgttgt tcatgttcct ggtggggctg
     8761 gagttcgacc ggcgcgtcat acgtcagcag gcgggcacga tgggctggct cggcgtcggg
     8821 gcgctcgtgg tgccgttcgg gctcgggtcg ctgttcgcgc tctggctgct cgacgcacac
     8881 ccgagcagcc agcccacggc gttcgtcgta ttcctcggta cggccatggc cgtcaccgcc
     8941 ttccccgtcc tcgcacggat catcgtcgac cacggcctgc tcaacagccg ggtcggcgga
     9001 ctcgcgctgg cgctggcggc ggtgggcgac gtgatcgcct ggacggtgct cgccgtcgtc
     9061 gtggccaccg tcggagcgga cgggcattcc tggcggctgc tcctgctcct cccctacgcc
     9121 gcgatcatgg tgttcgtggt cccgcggctg ctgagcagcc gtctcgtgaa ccggctcccg
     9181 cagcgcgcga ccgtgctgct cgtgatggcc ggtgtgctcg cctccggcgc cgcgaccgag
     9241 tggatggggc tgcacctgat cttcggggcc ttcctgttcg gcctcgtcgt cccccgcacc
     9301 gggctgcgcg gtggcttccg ggaggggctg ggcacctcgg tcgagccgct ggcgtccttc
     9361 ctcatgccga tctacttcgt ggtcgccggg ttccgggtgg acctctcgca cctcgacgcc
     9421 gacgcgatcg gcgagctgtt gctgatcctg ctcgtcgcgt gcggcggaaa gctcctcggc
     9481 gtctacagcg gtgcccgggc cgcccgcctc gaccaccggt cggccctggg gctcgccacg
     9541 ctgatgaacg tgcgtggcct gaccgaactg gtgctgctga tggttggcct ctccatgggg
     9601 ctcctggatc ccgacctcta ctcactgatg gtcgtgatgg ccgtcgtgac cacggtcgcc
     9661 tcggggccgc tgttgcgctc cagcatcggc tcgtcgatga aggacgagga agcactcgga
     9721 gcgcgggtgc cggtgcccag tgcgccggtc gaggagcggg agcaacctca ggcggggcga
     9781 ccgtagttcg ccacctccag gggggacaca tcgagcgtca actactactt gacgaccctc
     9841 atgcgtcaac ttaaagttga cgcatgagcc cactcgacat cagcctcgcc gacctgatcg
     9901 cccgtctcga cgaggagctc cccgaagcca acgaactggc ccgtatcagc gaggcgcgac
     9961 tgcgcgccca gaccctgtcc gacctcggtg accagctcat cgaccactac gtcagcaagg
    10021 ccaagcagac cggcgcgtca tggaccgaga tcggcgacgc gatcggggtg tccaagcagg
    10081 ccgcccagca acgtcacgcg cccggcccct tcgagcggta caccgagctc aaccggcaca
    10141 gcatcgtgct ggcgcaggag gccgcccgaa cgcataagca cgacttcatc ggcaccgaac
    10201 acatgctgct cggcctgctc ggcgaaccgc gcggcctggc atatgaggtg ctgctcgcga
    10261 agaccgggtc ggagcagcgc atccgcgacg cgatcgagga agcgctgccg ccggccggcg
    10321 agaaggcgct gcgggggcac atcgcgttcc ggccggagag caaggaggcc atcgagcagg
    10381 caggccgcgc gtcggccgac ctcggccacg actgggtcgg cacggaacac accctgctgg
    10441 gcctgatccg cgccgaggag agccccgccg cgcagatcct gcgcaccctc ggcttcacgt
    10501 cagatgagct gcgcgagacg gtcaagaccg aggtcgccca acggtccgcc acgcgcgacg
    10561 agcggtagcg aaaggggcag tcaccgcgga gaaccgggcc ggcacagcct tcctccctga
    10621 cacgggatgg tgggctcgtg ccggcaacct tccgcccgtc ggcgccaaaa gccttgtgtg
    10681 ggtgagccgc agccgtgcac tacgactcat gtcgaagccg tcagtaaagg gccagatcca
    10741 aggcgagaca catgcgatcg caggccgcag ttacctcccc ggcttcgcag aggtgagcag
    10801 gggccggccc ctcactcgtg gaagcgcgtc gtctcggcca gcggtgcgcg ggggatgacc
    10861 ggcatggtgg ccgccgcccc cggctcgggg tagccgaagg agatgccgaa gagcagcttg
    10921 tccgtggagg ggccgaggac ggagcgtacg gcgtcggcgt agaagccgag gacgccttgc
    10981 gggcagctgg cgacgccgtg ggctgtcatg gcgagcatca gggtctgggc gtagatgccg
    11041 aggtcggcgg tcatgcgctc gtccgcgtcg gcggggaccg agagcagggc cacgtggggc
    11101 gcgccgtaga agcgcagccc ctccaggaac gcccgccgcc gcccggcgcg gtcgctccgg
    11161 gcgatgcccc gtgcttcgtg catgatcgcg ccggccgcat aactgcgttc cgcggcggcc
    11221 ccggtgtagg ggtgcagcgg gaaatcgggg ctcggcttgc ccgattcggc ggcttggacc
    11281 agtgcttcgc cgagccgttg gcgggccccg gcgctgacga cgtcgaccga ccagggctgg
    11341 gtgttcgagt gtgagggggc cgcggccgcg agggcgaaga ccgcggtgat gacggtgtcg
    11401 ggtaccggat cgggccggta ggcacggacc gcgcgccggc cacggatgag ccgctcggcc
    11461 acaagtggct ccagagaggt ttcgagagaa gtcacgagca ctcctttctg tgggtgcgtg
    11521 ccacggatcg gtctccacga cgatccgggc cgggcacgga cggtccgttc accgacgggt
    11581 caggcccgcg gggcggggca ggacgaggcg ggagatggag cgcccctcac cacggcaggt
    11641 cgcaggaacc gtgcaggcgc tgtgcctcga ttccgcggcc gcgacaggcc gccacgaacc
    11701 gttcggcagc ctgcaccggc gccgcgttct cgtcgaaggt cgtggtcgtc aggtaccaca
    11761 cccagggttc gtggcccatg gcgtagacgt aggcccggtc gcacccgagg gcctcggcga
    11821 gtgccatggc gccgatgtcg tcattgccgt tcaggcggcg gcgcacggcc atctcacgtg
    11881 cgggctcgtg ggtgaacagg ggcccgtaga gccaggtcag cggggcgccc tcgcactcca
    11941 tgcccaggaa gagcacatcg accttgccga tggcccgccg cacatgcgcg tacgccgcgg
    12001 ggtcgatcgt ggaggtgtcg gcggcgaaga ggacggaccg gccgtcggac tccagcagcc
    12061 atgcggactt ggagatggcg aggtcgccgt gctcaccgaa gaaggggacg gcggtgagcc
    12121 ggcccatcgc cgtctcgatc tgctgaagct cgccgagttc gatcacccgg gggaagcccg
    12181 cggcctccaa cgccagccgc agcgacgggt cctgaagcga tcccgcgtcc gaccggggca
    12241 cgacgatcgt gccgatccgg gtgcgcaggc ggaggagcga ttccagtacc aagtggtcct
    12301 ggtgcccgtg ggtgatcagg acgtggtcga tgtaatcggg cagatcgctg tcgaccaggc
    12361 ggggcccggc gcccgggaac gcgggcggca gcagggggtc caccaggatc gcgccctggt
    12421 cgttctcggc caggacgcag gcgtgtccga ggtagcggat gcgcggctcc gtgaccggct
    12481 ccctgcgggt ggccttcgcc ggggcgtcgg ccgcggtgaa gtagggcgcc agcttgcggg
    12541 ccgtgtcgga ggtgagctcc agggcgtccg cgacctcgcc gagcggccgt ggggtgcgca
    12601 gcgtcgagaa catgacgtcg acgccggggt ggtggaaggg caccggcagc acggtccgct
    12661 cgtcggtggc gagacggggg gtggagaggg cgaaggggcg gcggtcggcc cggaggggtt
    12721 ccagcgcgag ggactgaccg tccgtagagg cgtagtcgct gcggtagagc agggcctcga
    12781 tcagccggaa cgaggcgttg tcctggaggt cgtagaccag ctccacatag ccctggagcg
    12841 gctccggcac cagggggtag agctcttcga gtggcgcgcc cggggccgcc ttcgcgagca
    12901 ggtcctgaag tgtgtccacc gcggtgtcga attcgagcag ccgggcggcc cgccgccggg
    12961 tgtccgcgat cagggcttcg acatccgccg agcggtcgcc gccgaggtcc atgaacgggc
    13021 cgccggccag cgccggtgtc cgggaggacc gctggtgcac cgccggtgct tccaggtacg
    13081 aggtcatgat gggcagctga cggcgggcga tattgcgggc cgcggtgccc ggcgagagca
    13141 ggtgcgacca ggcgtaccag tggtcgatca ggggctcgac gacgacgtcg gagcgcagcg
    13201 agacgggctg ccgggtgttc gggatcgtat tcatcggacg cgccttccct gtccggcccg
    13261 gactcggtcg agggtgtagg gggtgaggcc gccgccgtcg acgatgccct gaagggctcc
    13321 gaggtcggcg aactccatct gtcggtccgc gcaggtcacg acccggcggg agacgtccac
    13381 actgaccggt gcaccggtga tcgactcgtc gaagccgtgg tcgatgacga cgggaagcag
    13441 caggcccatg ttgacgcagt tgcggaagaa gatgttgccg aaggatttgg cgatcacgat
    13501 gcgggcgccg gcgtagtgca gcgcctgcgg ggcggtctcc cggctggaac cgcagccgaa
    13561 ctccgtcccg gcgaagatca ctttgaaggg ggaggtgccg gtgtccgggt cgacgaacgg
    13621 cgtctttgcc gggtagtcga cgagtgcgat ccgggcgagc tgatccggcc cctcgtaggg
    13681 ctcgtaacgt cccgggctca tcacgtcggt gtccacgaag tcccccactc cgtaggcgag
    13741 gccactgatg atcatgacgg caacccttcg ttcccggccg acgcggcgcg gcgtttccac
    13801 gccatccccg acagcacctc cagcacaatc cggttcgcga gataggccgt gatctccccc
    13861 ggcccgtcgt agggcggcga gagctcgacg atctccgcgc cgacgaggtc cacgcgctgc
    13921 gcgcaggtcc ggacggcgtc aagcagctcg cggctggtca gtccgcccgg ttcgggcgtc
    13981 cccgtcgccg gggccatgcc cgggtcgacg acatcgatat cgatcgtcag atacagcggg
    14041 ccgggcccga tctggtcgag gacgtcgtcc aggcaggtgt cgaggccgcg ggagcgcagc
    14101 tccgacatcg tgagcgagcg caccccgagc ccggccgccc attggagcgt gcgcggcccg
    14161 ggccagtacc cgcgcagccc gatctgggtg aaccggtcac ccggcacggt gccggactcc
    14221 aggagccggc gcatgacggt gccgtggccg tactccgctc cgaagtcgct ggtgtccccg
    14281 atgtccgcgt gggcatcgaa gtggaccacc gagaaggtcc cagggccgcg ccgggaggcg
    14341 atcccgcgca tcgtcggcca ggcgatgctg tggtcgccgc cgagtgtgaa ggggatcgct
    14401 cccgcggcca cgacctcgct caccgtgcgc tcaaggagct ggtgggcccg ctcggtctct
    14461 cccggagggg tgggcacgtc cccggcgtcc acgatcttga gttcggtgaa cgggtcgacc
    14521 ccgaggccga gatggggccg gtaggggacg tgcggcaggt agtcggtccg gcggatggcc
    14581 tgcgggccga accgtgtgcc cggccggtgg gacgtggtgc cgtcgaaggg cgctccgagg
    14641 atcaccacgt cggcgcccgc gtacccggcg gggctctgtt cgcaccgtgg cagcccgagg
    14701 aacgaggtct ccgggccgaa caccccgcgg tagtcggccc ggcgcaccgc gtcgtcgtag
    14761 tcctgtggtg cgtcggcggc gggtccgccc ggcccgcctg gcgtggatgg ggtcatcgct
    14821 gggtttcctc ctccgccacc acggcgtcga acgcgtcgca gaccgcggcg gccatctctt
    14881 tggtggtgca gggcgcgctg cccggtccgg cgatgtcggg ggtgcggcac gactcgaccg
    14941 cccgctcgac gccgtcggcc aggtggtccg cccatcgggg ggcgccgaag gtgtgacgca
    15001 gcatcagctc tacggaagcg atcgtgccga gcgggttggc gtgtccggtg ccggcgaggt
    15061 cgggggccgt gccgccgacc ggctcgtaca gcgcgaaccc ggtggggctc agggtggccg
    15121 aggggagcag ccccagcgag ccgcacaccg caccggtgat ctcggagagc acgtcgccga
    15181 gcaggttgct ggtgacgatg acgtcgaagt cggccgggcg caggaccatc tgcatcgcca
    15241 tcgtgtcggc gtacatgtcc cggacctcga cgtccgggaa ggccggtgcc tcctcggcga
    15301 ggacctccag ccacagtccg aagacgtcgg ggatggcgtt cgccttgtgc accagggtga
    15361 ggcggcggcg ccgggcctcg gcgtgctcca gggcgcagcg cacgatgcgg cggatctcgt
    15421 cctcgcggta gtacatctcc tgcccggccc accgttggcc cgcgtcgacc cccgtccggc
    15481 gtcgcccgta gtagacgccc gacacgagtt cgcgcacgag cagcaggtcg acaccgtcga
    15541 gacgttccgg ccggaggggc gagacatcgc gcagcgcgcg cagcgggcgg gccgggcgga
    15601 ggttggcgaa caggtcgtag cggctgcgca gttcgccgat cggttcgtcg gccgtcgcgc
    15661 cgaacaggac cgcgccgtgc ggtgtcgccg cgacctggtc gatttcgtcg cgcaccgcgt
    15721 cgggcagcca ctgtccggtg cgctcgtacg ccgggagccc caccgcgtgt tcgcggatcg
    15781 tggcgtccag tccggcgcgg tcgaggacgt gttccagtac gtggcgcgcg gcgcccacga
    15841 cctccggccc gatcccttca ccgggaagga cgagcaccgt cggtttcgtt gtcggcgtca
    15901 tcggctactc cgtgatccgg ccggcgagcg cactgcgtgc ggccacgatc ggcgatgcca
    15961 ggtagacgga cgacttggga ttgcccatcc gcccccggaa gttgcggttg gtcgtggaca
    16021 ggcagacctc accgtcgccg acgaccccgc cgtgcgcgcc gtaacacgcc ttgcagccgg
    16081 gcgactcgac gaccgccccg gcggcgagaa gcgtcgacat cgtgccggac agggccagcc
    16141 ggcggtagat ccccatggtg gccggcacga tcatgagccg tactccgggc gccacccgct
    16201 tcccggccag ctcggcggcg gccacctcga tgtcgtcgta cttcgctccg gtgcaggacc
    16261 cgatgtagac ctggtccacc cggatgtggt cggccatcgc ctcgtcgatc gagtgcacat
    16321 tgtccggccg gtgcggatag gcgacggcgg ggcgcagttt ctcggcgctg tattccaggc
    16381 ggcgcgcgaa cggggcaccg gggtcgctgg tcaccggctc gtacgggacg gtccgcggcc
    16441 gtgcggccag atactccgcg gcggcgggcg acagggccat gatgccgttg accgcgccgg
    16501 cctccacgac catgttgcac agcgtcatcc gctcctcgac cgacatcgtg tcgatggtgg
    16561 agccggtgaa ctcgatcgac cggcccgagg cgccgcccat gccgaggtcg ccgatcaggg
    16621 tcaggatcac gtccttggcc aggacgcccg gcgggagttc gccctcgatc cggacctcga
    16681 tgctctccgg gacccggaac cacagatcgc cggtgtagaa ggcgttgacc atgtcgatca
    16741 tgccgacgcc ggagccgaag gcgttgaacg ccccataggt caccgagtgc gagtccgtgc
    16801 cgagcaccac ggtcccgggc tggacgagtc cctcgtcgca catcatcacg tggcagatgc
    16861 cgtagttctc gccgtacggg tagtggtgtg tgatgccctg ctcggtggcg aactgggtca
    16921 tgccggcggc gagtcggcgc gattcggcgt ccttggcggg tacgagatgg tcctcgaaga
    16981 gggcgatccg ctcggggtcc cacacggtcg cgtccgggcc gaacgcgtcg cggaactcgc
    17041 ggcggagacc ctcgcacacc gggtcgtggg tgaacgccat gtcgatgccg acctcgacga
    17101 tctccccggc gacgacatgg tcccggcccg cggcccgggc gaggatcttg tgggtcatgg
    17161 tctgcggaat catgcggaga ctcccctcac ttcgagcagc tcacggatct ccgacggttc
    17221 gagccagcgg tcgtgcgcgt gcgcccgtgc cagcaccgcg tcgacgttga cgtcatcgac
    17281 cggggccccg accgaggcga gcgcctcacg ggcggcggcc cgcccgctcg tcggcccgac
    17341 catgatcgac tgggtgcgtc cgagcacggc ggcgggcaca ctggagaaca ccaggtcctc
    17401 cgcctcccgc ccccagcgcc gggccttcac cagggccgcg acatgggtcc ccgtgcacgt
    17461 ggcgaaggcc tgatcaccaa tcaggggcgc gttgcgccgc accggggagc ccgtcgcctc
    17521 ggcgaggcgg cggcagtgct cgaccacccg gtccatccgg taaccctggt gtccggcctg
    17581 gtagaggtac atcagcaccg attcgagcgc ggtgttcccc gctcgctccc ccaggccgag
    17641 gaaggcgccg ctgatggtgt cggccccggc ctcggcggcg gcgatggcgt tcgccaccgc
    17701 gagcccgcga tcgtcgtggc cgtgccacca gatcttcacc gccgcgccgt ggttgccgga
    17761 cggcaggccg gccagcgcgc gctgtacggc cgcccgcacc gcccgcacga tctgcgcggc
    17821 gccctcgggg gtcgactccc cgaccgtgtc gcagacggtg agcacctccg cgcccgcacc
    17881 gaccgccaca tggaccagct gttcaagttc ctcgggcggc gtacgtgtgg cgtcctccag
    17941 gctgacgccg aacctcgtgc cgtcgtcccg ggccgccgat cccgcggccg tgatgcgctc
    18001 cagaacgctg tcgagggtcc agccctcgac ccgccgccgc agcgggctgc atccgacgaa
    18061 gaagtcggcc cacacatcgc ggtcggtgcc ccggttgagc cggctgatcg gggcgatgct
    18121 cgccgggtcg gccagcgcca gaaagcgcgg caccatcggg agaccgcggc ggtcgaggtg
    18181 ttcgacgagt tcggcggcct ccgcgagggc gcccgctgag ctcgacggaa agccgagcat
    18241 ggccgcctcg accccgatcg ccgcggcgga ctcgaccagc gttttcttca cttcgacgga
    18301 gggatggtgc acaaaagcac cctgcaaacc gtcccgcaga ctgtcgtcct cgatcccgac
    18361 gtgtgtaatt ccgcgtgatc gcggattcca ggtgaacaat tcctcggcgc tcccagacat
    18421 cactccacct ctaatcgaga ccggccagac agcctgacat cggtccgccg accgaaaaga
    18481 aaagcaacgt gcagtgctgg tgtaacagat cggatcaccg gtgcaccagt gttccgaggg
    18541 gaatctaaag cccaccctaa acgggaccta aacgatgcct gaaaggcagc tgacggaccg
    18601 cctgaaggat aattcggatg ctcttgaaca gccgtcagga ctgtgttctg gtggagctcg
    18661 ggacagcaac ggtcatcgtc agtcccattg cccggcaaat tccccttgcc ggcaatctcg
    18721 tccggatgcg gccggaggtt tcaggtgtca atcggcatag aaaacggaac gagcgctcgt
    18781 cacccgcgtt gggaggacgt gccccaggcc gagtggagtg atccgcgatg gcagatgacc
    18841 caccggctgc ggcgcccttc gcagctgcgc gacgtcatca agctcaccga ggacgaggag
    18901 gcggcactcg gcggggacga cctgttccgg gtggacatca ccccgtactt cctcagcctg
    18961 atcgacgggg acgacccgca ctgcccgctg cgtctccagg tcatccccag ctcacgggaa
    19021 atggaggcct tcgacggaag gcttcccgat gccaactcgg agatcgagca cgagccggtg
    19081 cgcgggatca ttcataaata tcccgaccgg ctggtgatgc tcgttacgag ttcctgcacg
    19141 tcctactgcc gttactgcac ccgcagccgg ttcgtcggcg acggaaagca gaactacagc
    19201 cactcggact gggcggagca actccggtat atccgggatt cgccacaggt acgcgatgtt
    19261 ctgatcaccg gcggcgaccc gctgtcaatg gcacgcaacc ggctggccga aatcatcacc
    19321 gaactccggg cgattccgca tgtcgagatc atacgcatcg gcacccgggc cccggtcttc
    19381 aacccgttcg tcgtcgacga cgacctctgt aagttgctcg cggacaatca cccgatctgg
    19441 ctgaacatcc acgtcaacca cccctacgaa ctcaccccgg aactcgccca ggcctgctcc
    19501 cgtctctcca gcgccggtgt ccccctcggc gcgcagacgg tcctgctcgc ggggatcaac
    19561 gacagcgtcg aggtccagcg ccggctgtgc accgagctcg tccgtatgcg ggtgcgtccc
    19621 tactacctgt accaatgtga ctcggtgcgg ggcgcgggcc acttccggac cagcgtcacc
    19681 aagggcatcg agatcatcga agggctgcgc ggacacatca gcggcttcgc ggtcccgacc
    19741 tacgtggtcg acagccccgg tggcggcggg aagatcccgg tcggtcccaa ctacctgctc
    19801 agcctgtcgc cggagcgggc ggtcctgcgc aactgggcgg gcgaggtctc cgagtaccac
    19861 ggcccgtcgg ggtaccggtc ggggacgact ccgccgctgc gggggccgaa atcgcatcgt
    19921 gcgcccaccg aggtgcccac ggtgtccgac cggctgtccg ccccgcagac gccggccgaa
    19981 gacgcggagg gcttcgaggt atgagctcgg tgcactccgg gcccgccgtc caggccccag
    20041 aaagtgacgg tgtccggcac tccgtcgacg aggtgctcgc ggccgccgtg gtcgtgctcg
    20101 ggcggtacga ggaccgggat caactcgccc tggacatcac ggccgccccc gcggacgcgg
    20161 cacccgggac cgccgcggtg caccgggtcg tcgtggactg tgccccctcg gccaccttcg
    20221 cgcaggtgcg caccgggctc gccggccaac tcccggcccc acggcccgcg gggcgctgga
    20281 ccgtccaggt cgccgacccc gatgacctcg gcccggacgc cggtgcccgg cccgcggggc
    20341 ggggcgaact caccgtgcgg cagggcgccg atcccacgct cgtcctcgac cacccgcacg
    20401 cgtccggtcg cggtctccac gaggcggtca cccgcgtgct cgccgccggc accgcccacc
    20461 ccggacagga gctggccgaa ctccccgtgc tctccccggg cgagaccgat atccagcggc
    20521 agcggctcac gggcgaaccg tccccggtac cggcggagac cacgatccat gagctcatcc
    20581 gggacgcggc cggtcggcac cccgagcggg tcgcggcggc ctgcgacgcg gagagcctca
    20641 cgtacgagga actcgtggag cgctccgatc gggtggccgg ggccgtgctg gcccacggga
    20701 tcgcgcgggg tgaggtcgtg gccgtcgtcg ccgagcggtc gtgcgcggtg ctcaccgcgg
    20761 ccctcggcgt gctcaccgcg ggcggcgcat tcttcctgct cgaccccaca ctgccggcgg
    20821 cccgccggga acaactcctg gcggccgccg gggtgcggct ggtcgtcacc acccgggccg
    20881 ggcgtgccgc actcacggcg gaccgccccg ccctggtcct cgaagacctc ggatcggccg
    20941 acgccgtcgg ggaccgcccg aagctgcacg gtgacgatct cgcgtacctc atgttcacct
    21001 ccggctcccg gggcaagccg aagggtgtcc tggtccgcca ccggtcgttc gtcaaccgtc
    21061 agcggtggct catcgaccgc ctcggcctcg gcccggagga tgtgtcgctc gggcggacgg
    21121 cgctgtcgtt cgaccccgcc gtctgcgaga tgttccgtct gctgccggtc ggagggcggg
    21181 tctggttcct gcccaccggc cacgagcgcg acccggcccg ggtgctcgac gccatcgagc
    21241 gccggcgcgt caccgtcgtc gacctggtgc cctctcccct gcgcagcctg ctggaacacg
    21301 tctccacgct cggcctcttc tccgcggtct cgtcgctgcg gtgggtgctg gccggtgccg
    21361 agaccctgca cccctggctg gtcgagctgt tcgaggaggt cgccggccgc cgcggcggtg
    21421 ctcatctgct caacggctgg ggagcgaccg aggtctgtgt cgatgtcacc tcgttcgact
    21481 gctcggtcgg accggtccgc gagccggtgc ccgtcggccg tccgatcccg gggaccgggg
    21541 tcgccgtgct cgaccgtcac ggacggttca cgccgctcgg ggtgccgggt gaactcttcg
    21601 tccgcggccg ctgtctcgcc gcgggctacc tcaacgacac cgagctgacc gacgagcgct
    21661 ttgtgcaacg tccggtcgcg gggccggagt tgctctaccg cagtggcgac cgggtccggt
    21721 ggcgcgccga tgggaatctg gagttcctgg ggcggctcga cgacgaactg tcggtccgcg
    21781 ggcagcggat cgcgcccgcc gagatcgagg ccgtgctgcg ccgccacccc gccgtggacg
    21841 acgccctcgt ccgcaccgtg ggcgagggcg cgtcggaggc gggcagcgag cggctgatcg
    21901 cctgggtgac gcacgacgcg tcatcggctc cgcccgatcc gggcgaactc cgcacccacc
    21961 tggccgagtt cctgccgtcc accatggtcc ccgaggccgt ccacgtgctg gacgccttcc
    22021 cgcggaccgt gcacgacaag gtcgacgtca aggccctccc gaccacctcc ccggcgcgtg
    22081 cggacgactc ggcgacgggc ccgctcccct ccccgtccgc gtcggtcgag gacaccctcg
    22141 ccgccctgtg gcgggaggtc ctgaacggtg cggcgagcgg cccggacgac gatctgatcg
    22201 cccggggtgc cacctcgctg gacgccgctc gggtggcaac gcgcgcggca gcgagcctgt
    22261 gcgggcgcct ggacgtgatc accatcttcg cgcaccccac gatccgcgcc caggcagcgg
    22321 tgatccggga ctgcgaccac gcctcgtgcc gggtcgcccg cctcgcgccc acgcctccgg
    22381 ccgagacggc cccggcctcc cacagccagc tccgccactg gatcacgagc cgcttcgacg
    22441 ccacgtcctc ggcgtacaac atcgcggtcg gcatcgagct ggccgaggtc cccgaccccg
    22501 ccgtcctgcg cacggcgctg gacgaactga ccgtgcgtca cgagattctc cgcaccacgt
    22561 tcgcgctgga ggacggcgaa ctcctccagc gcatccggcc cccgcaaccc ggctgggtgc
    22621 ccgtggaggt cggtgcggcg gccgacccgt cgcgccatct gcgggcggtg agcgagcggc
    22681 cgttcgacac cgaggccggg cccctgctgc ggctcggcct gatcaccccg gccgatacgg
    22741 agcggacacc cgaccggggc accgtgctgt acctggtgat ccaccatctg atcagcgaca
    22801 cctggtcgtt gacgctgctg ctcaccgagc tggcggcccg gtgccgggcc ctcgccaccg
    22861 gggacggccc ggccgaactg ccgcccgccc gcctccagta ccgcgactac gccgcctggg
    22921 aacaggcgcg gctggccggt ccggcggggc agcggatgcg cggcttctgg accgaccggc
    22981 tggccggacc gctgccggcc ctcggcctcc cgctggacgc cccgcgcggc tccgcgaagg
    23041 tccccggcgc cgacgtgcag cgcttcgcgc tcgatcccga ggtcaccgac gccctgcggt
    23101 cgtgggccgg gggcaaccgg gccaccatgt tcatggcgct gctcaccgcc acttccgcat
    23161 ggctgcaccg actgaccggc cagcgcgatc tggtggtcgg taccccggtg gccgggcgcc
    23221 cgcacctcga cctcgaagac gtcctcggct ccttcgtcaa cagcgtggcc ctacgggtcg
    23281 ccgtggaccc ggaggcatcg cccgaggagc tgctcgccca ggtccggtcg accgccctgg
    23341 aggcgttcgc ccacgaggaa taccctctcg acctcctcgt acgggacctc ggcctggtgc
    23401 gcgaccccga acgctcggcc ctgttcgacg tgatgctggt gctccagaac gcgcccgggg
    23461 cccggacgga gtccgtctgg ggggagccca gcgcccgccg ggtcgatgtc gaccgcggcg
    23521 tcggcaagct cgacatgatc gtcacctttg tcgaggacga ggacgggctg cgcggcgaga
    23581 tcgagtacga ctcccacctc ttcacgagca cgacgatcga gcgctggctc gccgggctgt
    23641 cgcgcacgat cgcggcgctt ccgcactccg gcggcgcgac cgcggccgcc gtggcccgct
    23701 cggcacttga cgccccggcg gagccggttc tgctccacac ggcggtggag cgccatgccc
    23761 ggctcactcc cgagcggacc gcggtggtgt gcgaggaccg ggtcctcacc tacggggaac
    23821 tcaacagccg ggcgaaccgg ctcgcccgcc ggcttcgcga cgaattcggc gtgacccctg
    23881 ggaagatggt cggctacgcg gtcgagcgct ccgagcgggt gccggtcatc cagctcgcgg
    23941 tcctcaaggc gggcggcgcc ttcctcggga tcgatccggc ccaccccgag gcacgcagcc
    24001 gcgccgtact cgaagacgcc cggccggtcc tgctggtcgt cgacggtcac gagcagggct
    24061 gccgtccgga gggcgtggag tggctccccg tgctcgccct cgatgacgca cccgagctgt
    24121 ccgacgacgg tgagggggcg gccgatctca ccccggccgc cggcccggac gaccccgcgt
    24181 acgtcatcta cacctccggc agcaccggca cgcccaaggg tgtcatggtg gagcaccgga
    24241 acgccctcgc gctgctgtgg gccggcggct ggccgttcga cttccgggac gacgacgtct
    24301 ggacgtcgac gcactcgttc gccttcgact tctccgtctg ggaactccat ctgccgctct
    24361 cccgcggcgc ccgggtcgtg atcattcccg aggcgacgcg ccgggacccg cgcaagctgc
    24421 tcccggtcct cgtacgggag cgggtgaccg tgctgtccca ggtccccagc accttcgagc
    24481 gcgcggtgga cgcactcgac cgccgcccgg aactggcgcc gacctccctg cgctacgtga
    24541 tattcggcgg cgagcccatc aatcccgggg ccgtccggcg cttcgcggga cacctgcccg
    24601 gggtggacct ggtcaacggt tacggcatca ccgagaccac cgtcttcacg accttcaaac
    24661 gactcgacct ctccgaggcg cccgaagcgg ccgatgcgcc gccgtccgac atgcagaaca
    24721 tcggccgtcc gatcggcacg atgagtgtgg aactgcggga catggacggg aagttggtgc
    24781 ccgagggcag cgtcggggag atcgtcatca gcgggcccgc ggtggcccgt ggctacctcg
    24841 gccggcccga ggagaccgcc cgggtcttcg gggtgcacgc ggacgacccc ggggccgggg
    24901 gccatgacgg ccgcccgccc cggaggtggt accgctccgg agacctcgcc cgccgcctcc
    24961 cctccggtga cctggtgttc gtcggacggc gggaccgcca ggtcaagatc cgcggctatc
    25021 gggtggaact cgaagaggtc cgctccgcga tcctgagcac ggggctgctg gccggcgacg
    25081 ccgtgaccga cgtccggacc gggccgaacg acaccccgac gatggtggcc tacctggacg
    25141 accgcgaccg ggagcggatc cccgctctgc gccaacggct ccaggagctg ctgcccgcgc
    25201 ccatgatccc cgcgtccttc gtcaccgttg acgactggcc gaccacggcc aacgggaagg
    25261 cggacctgga cgcgctccgt gcccggtact ccggcgaccg gcagacccct gccgaggacg
    25321 aatcggaggc gacgacggac cagggtgcca cgggcggcgc gcccgacaca ctggcctcgc
    25381 tgggggagct gtggggcgag ctgctcggcc actgcgacct cggtcccgac gacaacttct
    25441 tcaccgtcgg gggccattcc ctgctggccg tggcgctggt gaccagggtg gaggagaacc
    25501 tgggcgtcgt cctcggcctg gaggacgtgc tgacgcatgc cacgctcgcg ggccaggcgg
    25561 agctgatcga cgcccgccgc acaccggcgg aggaacagcc cgccaccgga ccggacccgc
    25621 tccccgcggc cccggtctcc ggcgaccacc cgttgtcgcc cgcgcagtcg gagttctggc
    25681 tgctcgacca gttccgggcc ccggggacac cggcggcgac acccgagatc ctggagctgg
    25741 gcaccccgtg ggaccccgcg gccgaccggg cggcgttcgc ccggctcgtc gagtccttcg
    25801 agatcctgcg caccgatttc cccctggcgg acacacaccc ccggcagcgg atccatccgc
    25861 acggccatga ggacgcgctc cggctgaccg acctgtcccg ctcacccacg gccgaggacc
    25921 tgcggaatct cctcgacgag gaggcggccc ggccgctgga cctcaccgag ggcccgctgt
    25981 tccggctcca tctggtccgg cgcccggaca cgtcgacgct cgccgtcgtc accgcccatc
    26041 acatcgtgtg ggacggcatg tcctgcgacg tgctcacccg gtggtggcag caggaccggc
    26101 aggcgcagcg ggcgggcgat gtcacccccc ggcgtccggc gcgtcagttc cgcgatatcg
    26161 ccgcccagca actcgactac ctccggagcc cggaggggcg cgcggaactc gcgtggtgga
    26221 ccgggcggtt gaccggagcc caccgcaccc gccccgatct cacaccactg ggcatcggat
    26281 acccgtccgg gccccgggac ttcctcgggt gtcgccaccg ggtgacggtg gacgccggac
    26341 gcacccgcgc cctccaggcg ctctgctccg acgcgcggac cacgctgttc gcggggctgc
    26401 acgccgtcgt caaggcgttt ctgttcgccc tgacccggca gaccgacctc gtggtgatgt
    26461 caccggtgtc actgcgggac gggcgggtcc tggaggagca gctcggcccg ctgatcaata
    26521 cggtcgccct ccgcgaccat gtcgagcccc gcgagccgtt ccgcgccctg ctggactccg
    26581 tacgccactc ggttgtcgac gcgctggccc accggcggat cccgccggga gacatcggcc
    26641 gggcgctggg gctggacgcc gacgcgccgc tggccgacat cggtctgaca ctccagcccc
    26701 ggacggggac caccgaggcc gcctggacgg aagaggtctt cggcgcgcac accccgctgt
    26761 ggttcgacat caccgagcag gcggacaccc tgcacgtcga gatcgtggcg ccacgtgccc
    26821 gtatcgacga cgacaccctc gccgaactcg ggcgggcctt cctccggatc gtggggctgc
    26881 tcctcgatca ccccgatgcc ccgctggacc aggccgtgga tgcccggccg gcggagtccc
    26941 cggcccccct gaccatcgag ctgcgctact gagcgctgat tccgggaccg gtgcgaagcg
    27001 gtccccgctg aaaggagcag aggtggacac tcaggaaata ctgtcggtcc agcaccacca
    27061 tgagccggcc gaccatgagg tctggcggca cctctaccgc cagcagttgg atctcgtgcc
    27121 actggccgcg ccggccatct acctggaggg gctcgacctg ctcggcctgc ccgccgatca
    27181 tgtgcccgat ctcgaccggg tgaacgagcg ctcccgcgcg atcaccggct ggacgttcgt
    27241 cgcggtggac ggcctggtga agggggccga cttcttcacc atgctcttga accggcgatt
    27301 ccccgtcacc aaccagatgc gcaagccgga ggagatccgc ttcgccgaac tgcccgacct
    27361 gttccacgac ttgttcggcc acggcccctt cctggcccac ccgcgcacgg cggatctgta
    27421 ccaggagttc ggccgtatcg gggtccgctg tgcggagcgc cccgatgaac tcgcgctgct
    27481 ccagagcatc atgtggacca ctctggaggc cggtctgata cggacacccg acgggctccg
    27541 ggcgctgggc ggcgccatcc tgtcctcggc cgacgagatc cagcagtgcc tcgacccggc
    27601 cgccgcgacc gagaccttcg acccggaggt ggtgcggcgc gcgacgttcg acatcctcca
    27661 gctccagaac cgctacttcg tcatcgagga cctcgcggag atcgagtcgg cgctggccga
    27721 cctggacgcc cgggtcgacg agggagaccg ctgatgacga agccgcagac cactacgggg
    27781 tacttcctcc gcggggatgt cgaggtcgag ccgctggtcg accgctggta tgcgtgggtg
    27841 cacctggtct ccccggcgac ggccgcgttc gtcaccatgg agcgtcatct gcggatgatg
    27901 gagtcctacg tccgctcccc cgcgatgcac gctgccgcgg cggcgaaccc ggcgacccgc
    27961 agcggcccgt tcctcgacct cggcggtgcc aaggtcgccg aggtccaggc gctgctggac
    28021 gcgacccgta ccaaggcgaa gcgccagcag gacttcgtgg cggcgttcgg cgagctggac
    28081 acgctcctgg agagcatgac cggtggcgcg ctggaaccgc tgtacccctc cgtcccggcc
    28141 gcgctccagg gcctggtgga gctggagtac gaccgccaca accgggcccg gtgccggctc
    28201 tacgaacgac tgctctacgc cgatgcgctg gccgacccgt cggggcagtg tctgcgcctg
    28261 gtgcgcacgg accgcgacgg cgaccgcccc ttcgccttct ccacgccccg cctgcccgtg
    28321 gtggaggacc cggacgacac cgacggcgcg gcctgggagg gcgccgtgga actcgacctg
    28381 cccttcgcca ccccggcgct ggacaccctg ttccgcgccc gcaccgaacc cgtcgatccg
    28441 gacgagctcg ccgacgagct gggcctggac gccggtgccc gtgcgcgctt ccgcgagctg
    28501 ttcaccacca ctcccccgcg gacgccggac gagcgcgcgg actcgcggcc cgggccgggc
    28561 caggtccggg tgacctactt cgggcatgcc tgtgtgctgg tggaggacga cgaggtcagc
    28621 atcctcgtcg accccgtgct cccctacgac cacgaatccg acgtgccgcg ccgctccttc
    28681 gcggatctgc ccgaccggat cgactacgta ctgatcaccc acgcccacca cgaccatgtg
    28741 ctgcccgaga cactgcttca gatccggcac aaggtgggca cggtcatcgt gcccggcaac
    28801 gacggcggcg ggctgatgga cccctcgctg cgcctcgtcg tcgagcacct gggcttcccc
    28861 gatgtccgtg aggtgcggga gctcgacgtc acccacctcc ccaacggggc gatcaccgcc
    28921 atcccgttcg tcggcgagca ccacgacctg gcgatccggt cgaagtccac ctaccacgtc
    28981 cgcctcggcg gcctgaccgc gctgttcggg gccgacaccg ccaacgtcaa cccggcgctc
    29041 tacgaccgcg tgcacgacct ggtcggcgac gtcgacctga tgttcctggg catggagtgc
    29101 gagggcgcgc cggcgagctg ggtctatgcc ccgtacttcg cccatccgct cgaccgggac
    29161 cacgaccaga gccggcgggg gcgcgcgtcc acgtgcgacg aggccctcga tgtcgtcgag
    29221 cgcttccgca gctcggcggt ctatgtgtac gcgatgggcg aggagccctg gctctacccc
    29281 ctactgggca tcccgtacac cgatgagtcc ctcgcgatcc gggaggccaa gcggctggtc
    29341 gagacctgcc atgagcaggg ccgccactcc gagcggctct acggtgcgaa gcgttggagc
    29401 gtgtcgtgag catctcccga atcgaggccc ttcagggccc ggcccaccag cagcagcgcg
    29461 ccgcctggct gacggccatg ccgtcccccg aggacgcctt gcactgggcc gactccgtcg
    29521 tcaccgcaaa tacggccgcc ccggggacgc gacaccgtgt cactctcggg ccggagagcc
    29581 gtcgccgggt caccgcggtg agcggtggtc agacgctggg cgatttcgtc gtcctgctgt
    29641 ccgccctcgt ggccgtcgtg cagcgcacct cggcacacga cgtggtctgg ctgtccactc
    29701 ccctgctcca cggcgtcgac agcccctacg ggtacgacga ccgggtgccg ctggtcttcc
    29761 gcccggagcg gcggggcagc ttcaagtcgc tgctggagca tgtgcgccac caggtcgcca
    29821 cctcgtacgc ggtccagggc tttccggtcc gcgacctgtg ggcgcaggcg gacggaccga
    29881 cggacaccgg tgtggtggtc gccgagacct ctctgcacga ggatgtggcg gtcgacgaca
    29941 gcaccgaact ggtcatcagg atcaatacgg cggagggcag tttcgacgtc gaggaccggc
    30001 acggccggtt cccggagtgg ttcgccgacc atgtcgtcgg gctggtcgaa aaggtgctgg
    30061 agtatctcga cgacaccggt gtcgcggtgg ccgacctgga cctgctcgac gacgacgaga
    30121 tcctccacca actcgacacg ctcaccgcca ccggcgtgcc cgcccacacg ccggacgact
    30181 cgctggcgac ccggttccgc gcggtggccg ccgccgatcc ggacgcgacc gccctcctca
    30241 cgggcggccg ggcggtgagc tacggcgaac tgcactcccg cgccgcgcag ttcgcccatc
    30301 acctccgcga cgatctgagc ctggccgaag gggaagcggt cgccgtcctg gtctcgcgcg
    30361 ccgaggacac cctcgtggcg ctgtggggct gcatgctcgc cgggaccgcg tatgtcccga
    30421 tcgacccgca cgccccgacc gaccgcatcg cgcagatcgc cgacgccgcg aaggccaagg
    30481 tcctggcgct gcactccagt ctgctgcacc gcctcacgga cctgcccacg ctcaccgtgt
    30541 gcggtctgga cctccagttc cccgcgggca cggcggcggt gtcaccggcc gagccgacct
    30601 ggccggcccc gcggggtggc gacgccgccg cggtcatcac gacctccggc tcgggcggga
    30661 ccccgcgcac gatcgtcctc gaccacgccg gcgtggtgaa cgtcgcgctc gaccacgtca
    30721 ccgagctcgg tctcggcccg agcgaccgct acctcgcgtt catggcgctc tcgttcgacg
    30781 gcgcgctgct cgacatcgtg atgacccatc tcgccggtgc ggcgctggtc ctcccggacg
    30841 agcaggagct cgccgatccg cgccgtctgg aagacctgat ggccgggcac gccgtcacgg
    30901 cgaccaccat gacgccctcc tatctgagtg cgctcgatcc gctgcggctg acggacctcc
    30961 gggtgctcat ctcggcggcg gagccggcca atacggcgga tctgctggcg tacgcggccc
    31021 gcggcgtctc ggtctacaac ggctacggcc cgaccgaggc atgtgtgaac acgacgctgc
    31081 accaggtgga tccgcagcgc gactaccacg gtgtaccgct cggccggccg cgcgcgaaca
    31141 tgcaggtcta catcctggac caggaccgga atctgctccc ccgacatgtc atcggcgaga
    31201 tcgcgatctc cgggcgcggt gtggcgtccg ggtacatcgg ggaccccgag cagagcgccc
    31261 gccggttcgt cccgcacccg ttccgcccgg acggcggtgt gttgcacctg tccggcgacc
    31321 tcggcggctg ggacgagaac ggggagttgg tcttcgccgg ccgccgggac cagcaggtga
    31381 agatccgtgg cttccgggtc gaacccaccg agatcgagaa cgcgctgcgc acgcacgacc
    31441 gcgtggagga tgccgtggtc gccgcggata ccgaccgcgg ggtgctcgtc gccttcgtcc
    31501 gcgagccggg cggccacggc cccgagcacg gcgcagtacc ggtcgacgcg ctctccgacc
    31561 acctcgcccg gacgctcccc gcctacatgg tcccgagcgc cgtgcacctc gtcgacaact
    31621 tccccaccac cgaacacggc aaggtggacc gtcgcgccct cctggacctg cacgagcggc
    31681 ggctggccga gcgcccggtc agcacaccgg cgaacccgct cgaaacgcgc ctgctggagg
    31741 ggtgggtgaa agtcctcggc ctgcccgcga tcgacgccga ggacgacttc ttccagctcg
    31801 gcggcgactc catccggctg atccaggccg tacaggccgc ggagcaggtg ggcatcacgc
    31861 tgcgcaccag cgacatcatc gagcagcgga cggttcgcgc gctcgcgggg atggtggccg
    31921 aacgcggcga tgccaccgag tccgtgacac cggccgtgag cgcgtccgtg agcctcaccg
    31981 acgacgaaac gcggcagctt ccggcgcggt gcgaggacgc ctacccgctg acgcacctcc
    32041 aagaacgcat ggtcgagtgg tccgccgaac cggacctgcg ggcgctgcac gcctaccact
    32101 gcgtcgcggg atggcggctg cgcgacggcg agctggacct cgatgtgctg cggcaggccc
    32161 tgcgcggcct ggtcgaacgg caccggtcgc tgcgcaccgc catcgtccgc gcggccggct
    32221 cgggacggct gctccagtgc gtgctgccgc cggacgccac cctcgtcgac accgtcgaag
    32281 cccacccgga ggacacggcc gacacggtgc tgaacgccgt cgtcgaggcc gatctcgccg
    32341 aggccttcga caccgacggc gccgcgccgt ggacccgctt ccacctcgtc gtacgctccg
    32401 cgaccgaagt cgatgtcgtc atgtccgcgc accacgcgct gacggacgga tggagcggcg
    32461 tccagctgcg caacgaactg ctcgacgact acggaaccct ccgtgccggc ggccgccccg
    32521 acaccgcggc gcccacggtg gactcctacc gggagttcgt cgcgctggag cggacactcg
    32581 ccgacgaccc gcaggcacaa ggcttctggg cggacgccct ggccacgctc ccggacggtc
    32641 tgaccacccc gcgccgccgg gagttccggc gggtgggcta caccgaggtc gtcgtgcccc
    32701 cggagcgggt cgaggcgctc ctcgccggca cccggaacaa gggcctctcc cccaaagccc
    32761 gctgtctctc cgccttcctc gccgcgctcc accgtcatgg cggcgctccg gagctgacgg
    32821 tcggcatcgt cgccaacggc cggtcggagc ggctcaccga cccgctcggc accacgggcc
    32881 tgttctggaa catcctgccg gtcaactccc gctgggacgc cgatacgcaa cccccttcgg
    32941 caacggcggt ccaagcccgg ctcgaagctc tggaacccta cgcgggctac ccgctggccg
    33001 gtcatgtcgc ggacgacgag gccatcgcgg ggtggttcaa cttcgtgcac ttccatcacg
    33061 cccgccaggc cgtcgaccgg ctgaccctgg tcgaggagtg catcgccctc ggccagctgc
    33121 accatccggt ggtgctcgcg gtgtcgctgg aaccggcgac tcccggcggc gccccccagc
    33181 tcgtcgccac ccttgagcac gacctcgacc ggctcgacga ggcctccgcc gaacggctga
    33241 tggccctctg gtccgaggca ctgtcctcgc cggccaccga caccccgggc tacgacgccg
    33301 tacccggcat accggaggaa tcccgtgaca ctgttcagtc ctgagcactc cgcgaccccc
    33361 gacgagaccc cctggtacga cgtcgtggtc tgcggcggcg gactcgcggg cgccaccttc
    33421 gcccgccagc tgcgccgtga acagcccgat gcctcggtcc tggtgatcga cgggcagacc
    33481 tacccggtgc cactggccgc ccacaaagtc ggcgagtcga cggtggacat cgcggggttc
    33541 tacttctcct ccgtcctcgg actcgccgag tacatggccg acaagcacct ccccaagctg
    33601 ggcctgcgct acttcttcgg ccaggcgggc cggccgttcg cggaggcccc ggaaatcggg
    33661 ctgtcgggct tccccgggcg gagcacctac cagatcgacc gcggtgtcct cgaaaacgac
    33721 ctgtacgaga tgaactgcga ggccggtgtc gagatcgcca ccggcagtat ggtccgcgag
    33781 gtcgacctgg gccccggtga ggactcacat ctggtgcagt acgtcgacgg ggagggggtg
    33841 ccccggagcg cgcgctgccg gtgggtggtc gacgccatgg gacgcgcccg gtacatccag
    33901 cgcaagctcg ggcttcagcg ccccaccgag ggccagttca acgccgtgtg gttccgcgtc
    33961 gcgggccggc tcgatgtcga ggacttcgtc tccgacgaca acaccgactg gcacgagcgg
    34021 gtgccgggcc gcaaccgccg gctctccacg gtccatctga tgggccccgg ctactgggtc
    34081 tggctgatcc cgctcggttc cggcaacacc agcgtcggca tcgtgacctc cggcgagatc
    34141 catgacatcg acggtatgag caccctcccc acggccgtcg agtggctgga gaagaacgag
    34201 ccggcggtgg cgtccgcgct gccccaccac gaggttctcg acttcctcgc cgtccgcgac
    34261 tacagctaca cctcctccca ggtcttctcc gccgaccgct ggggctgcct gggcgaggcc
    34321 gcggccttcg ccgacccgtt ctactccccc ggctccaaca tgatcgcctt cgagaactcg
    34381 gggctgatcg ggctgatcgg cgaggacgcc cggggcgcgc tgcgtccgga gcgggtcgat
    34441 gagctgagcc gtttcatgct cagtcagaac gactggctca cgtacaacat ccacagctcg
    34501 tactcgtact tcggcgagcc cctcatcatg gcgctgtcgt tcatctggga caccctgctc
    34561 tcctggacca cggcgacccc gcagatctac aacggcatct tcctcgacga ggagaaggcc
    34621 gccgcggtcc gcaccgcgac cccgggcctc tacgccctga ccgtgcaggt caagcgcctg
    34681 ttcaagcagt gggaacagaa ggcggggcgg ggccgggact tccgcttcat cgactacgac
    34741 aagatcccgt tcctgcacga ggcgtacgaa cgcaacctcg tggagggcaa gtcggtggcc
    34801 gacctcgtgg cggaccaccg ccacagcatg gccgtgctcg aagaggtggc ccaggccatc
    34861 ttcctcatcg ccgtggagga caccatgccc gagcggcggg cgcagttcgg cgagcacccc
    34921 tggctcaacg cctgggcgat cggcctggac cccgagcact ggcggtccgc cggactgttc
    34981 cagcccacga cgccacctcg ctccctcgac gagacgtacg cgaccctgac ggcactcttc
    35041 gacgccccgt cacccgagcc cgacacgaca ccggccgcgc tgccgatcga actgcggctg
    35101 tagggctgac agcccacttc cgacagccgg accggctctt gcacagcctc cccgtacccg
    35161 acccagtcat gacctgaaag accgccgatg cccgcggccg tcgtcgccgc gggcatcggc
    35221 gcggacccca gccggctccc acacgagccg ccgcagatca gctacccgag gagtgcccat
    35281 gatttcgacg tgtcgtcagt ggcacgagct gtccttgatc gagcgtcagg cacgtgccgc
    35341 acggcacgac ggacagccca catgggatct ctcagaggcc ctgttgcgcg gtctcccggc
    35401 gtcggcgggc cgcgtcgatt tccgcgccga gacctatccc gatccacaag gggaacggga
    35461 actccggcgc cgcatcgcgg cccgggagaa cgcgaaatac ggcctgtcgc tgaccgagga
    35521 ccacatcgtg gtgacgcacg gtgcgaccga ggccctgttc ctcctcgcac acaccttctt
    35581 gaaccccggt gaccgggtcg ccgtacaggc ccccagcttc ctcttctacc gggaaatcct
    35641 cgaaaacctc ggcgccacgg tcgtccccct caacgcggag cccgacagcg cccgtccggc
    35701 acggatgcgg ttactgcaca gcccgtcgaa ccccgatggc cgcgtgctcg ccgagggcac
    35761 cctgtccctg cacgccgagg cggcgcgcgc cgatggctcg ctgctcgtcc tggaccaggt
    35821 ctacgacgag ctgatcgtca gcggtacgcg tccccgtgag gaccaggccg tgctcgacag
    35881 cggccatgtg gtgaaggtga actccgtgtc gaaggcgttc ggttgccccg gagtccgcat
    35941 cggctggatc accacggcac cggcggtcgc cgaagtactc accggtgtgg ccgagcgcct
    36001 gcgcatgggc ccgtcgctgg tggctcaaca agcagcgacg gctctgctgg tccggccggt
    36061 ggacggaaac ctcgagctgc tggccgaacg ccgcgccatc gccctcgacg cgctctccac
    36121 actcgacctc ttcgaggagg cggcacctcc accgggcggc ctgttcctct ggctgaagct
    36181 ggccgacccg aacgcgagcg cccagcagtt ctgcgaccgg gcactggccg aggtgggcgt
    36241 acggctgatg cccggcctcg gattctggca gggaacggac gaccgggtac gtctctcgtt
    36301 cggcgcggtt ccggactacc ttgacgcggc attcgaccgc ctccgtcaac tgacggtccc
    36361 ctcacgacgg tccgcagccg gtctcaccac agcccatgga atcaggtgag ttctccgttc
    36421 ccgccagagg ctttcgagcg cgccgcacca tgaccgatat cgatcgccga cggccggcgg
    36481 gccgtcacga tacccaccaa gatccgaaat cacctggagc cggacgtctc actgatgggt
    36541 aatgacatga cgatgccgtc ggcgacgcag tccccgcccc gggaagggct gcgccgcaac
    36601 cgtgacttcc acatcttctg gatcggcgag acgatctcgc tcttcggcgc cgaggtcagt
    36661 ctcctcgctc tgccgctcac cgccctcgtc gtgctcggcg ccgacgccgc cgacctgggc
    36721 ctgctgcgct tcgtcgagta cctcccgttc ctcgccctgg cgctgccctt gggagtgctc
    36781 gtcgaccgga gcaggcgtca cccgctgctg gtgatcgcca acagcgcccg tgccgtgctc
    36841 gtcgggatca tcccggtgct cgcggcactc gggtggctgt ccatgtcctg gctggtgatc
    36901 ctcgccctgg gcatcgggac gttcaccgtg ctgttcgacc tgtgtcttcc ggcctacctc
    36961 ccgaagttcg tggcctcgga ggacctgctg tcggccaacg gtcgggtgtc catgagccag
    37021 gctgcggcgg aggtcgcggg gccgggcctg ttcggcttgc tcgtccagtg gctcaccgcg
    37081 cccctctgcc tggcactcaa cgccggttcc tacctcgtgt cagtcctttc gctgctgctc
    37141 atcaagcggc cggagcccgc ccccacccgc gtggtcggca ccccctggca ggacctctac
    37201 gacgggctgc gcttcctcgt acgttcacgc ttgatgcggg cggtgaccct ggccgggagc
    37261 ctctacaacc tggcgtgggc catcttccag accgcgttcc tcgtctacat gaacaaaatt
    37321 ctcgggttca acgtcggcat cgtcctcgcg gtgggagcgg ccggcggcct ggccggagcc
    37381 gcctgcgccc cctggctctc ccggcgcctc cccgtcggcg tcacctacct cgcggccgcc
    37441 gccgccatcg ccgtccccgc cctgctcatc cccgccgtca cggggcagcg caccaccctc
    37501 gctctcgtcg ataccgccct tctggtcctc atgaacggcg gtctcgcggt cttcagcgtc
    37561 ctcaccgcga ccctgcggca gagcgtcact cccgacggcc tcatgggccg cgtcgtggcc
    37621 ggctaccggg ccctggtctt cggcggcatc tccctcggcg gcctgatcac cgcctggctc
    37681 ggcaacctgg ccggcccacg cgccatcctc tgggtggccg gcgtgttctt cctctccgcc
    37741 ctggcaccgg tcctgctctc cccggtcccc cgcctacggg gtttcggcac ggcggacagc
    37801 cccctgagcg gcaccgaatc cgctgcagga gagcgggcag aggcttcgtc ggaccacaca
    37861 gaagcaggta gttgacgcat ctgccccaag gaggcgctcg ccgcggccga ccggccaacg
    37921 agccggcacc taaccgatgt cgggctcgga ccgcacctcg atccggtccc ccgtccgctc
    37981 catctccagc acgacgagct cgttccggcc ccgccgccac agatggctcg gggcgtaaag
    38041 ggtgacctgc gccccgaggg accagtaccg gccgagcgcg aacccgttga gccacaccat
    38101 gcccttgtcc cagcccggaa aggcgaggaa gccgtccgcg ggggtgtcga catggacccg
    38161 ggcccgatgg aacgcggggc cggtcggcac gtctccgctg ccgaacttca cagccgagag
    38221 gtcgtcgaga ggcaaccggc ggatctccca gtcgctcagt tcgtcctcac caaggagcac
    38281 cttgccgctg aggcccttgg ggtcattcag tccctccccg aagttgatcc gcccggtggg
    38341 atcgaccagg aggtcgagag tgccggacgc accggccacg gtgaagtcga cggtgtggtc
    38401 cggctggtta cggtcaaagg tgccgatccg cttgccgtcg ccgaacacca gcgcacggtc
    38461 gcccaggccc gtgagccgca gactcttggt cccctgcggc ccccgcaccc gggtgcggta
    38521 gtggatcagc ccgtaggact gcccgaccgc ctccatatga gcgggagcgg tacgccggat
    38581 cggagtgctc agcgcgtcga gggcgtccat cagcggcacc gactcgcgga cggcgacccg
    38641 ctgggccggc atacggcgcg gcgtggccgg caggggcgtg ctcggcaaag tgctgtactt
    38701 ggccagcacg tcacgcacct gatggaattt ctcggtgagt tcgcccgatt cgctgatcgg
    38761 ggagtcgtag tcgtagctgg tgacggtggg ctggtagtgg ctgccggtca ggttggcacc
    38821 cgcgtaccag ccgaagttcg atccgcccac cgccatatag aagttgatcg acgctccgga
    38881 ctcaaggagc ttctgcacgt cggcagcggt ctgcgctgga tccgtggtgt ggtgcggctc
    38941 tccccagtgg tcgaaccagc catcccagaa ctcggtgcag aacagcggct tgtccggctg
    39001 gaatttacgc agctcggcaa agggcccggc cggatccccg gcgaagttga cggtggagag
    39061 gaggtcgggg aggctgccgt tcctgagcat ttcctggctg gccccgttgg agcagaacag
    39121 caggctgtcc acgccctgcg cccgcatggt gtcccgcaga tgttccaggt gcgcatggtc
    39181 gtcgccatag ctgccgtact cgttctcgac ctgcatggcg atgatgggcc cgccacgtgt
    39241 ggcctgcaga tcgacgaacc ggggcagcag ttccgcgaac caggcgtcca ccgcccgctc
    39301 gtaggcgggg tcggagcggc gcagcggcgc gtccttgtcc ttgaggagcc aggccggcag
    39361 accgccgaag tcccattccg cgcagatata cggtcccggt cgcacgatca ccttgagccc
    39421 gacttcgtcc gcgatccgta cgaaggacac gacatcgcgc catccggtga agtcggtctt
    39481 cccctcgtgc ggttggtgga agttccaggc cacataggtc tccaccgtgt tgagccccat
    39541 ggcccgcatc cgcagcagcc ggtcgcgcca gtccttggga tgcgtccgga agtagtgaaa
    39601 ggcccccgag aggatccgga acggctcacc gtccagcagg aattcgctcc cgcgcacggt
    39661 cagcccccgc ggactgtcgg cctgcgccaa ggtcgtacgg ccaccgccca gggcgacacc
    39721 cacggacgcg gcccccacca cggccgcact cacaaatctc cgccggctga actgcgtcat
    39781 ctctgctctc ctcgactcga ccgaccgtca cgcaaggttc gaacatgttc agtggtgcgc
    39841 ggttctgtgc cttgagagtg tcatgtagaa cagaaacgag cacaagggtt cgtgactgaa
    39901 cacagttcag ccaggagcgg gcgctgacgt tcgctccgta gccttcctgg gcccccaggg
    39961 aagcgctccg ccatggcacg gcgggccgac aaaggtgccc gcaaccatgc cccctcgtac
    40021 cttcaccatc cggccctcgc ctgggtttgc tggtacgaca tcacccatcg actggatgcg
    40081 cgcccggcga ggcccgcagg agggggcacc gttgcactcg cacggagatc gtcgcgcgat
    40141 cgcagacgac agtcgtagac gacaagccac agcccgcccg accaccaaga aggcacgccc
    40201 gacgaccgac gccggtgccg gtgccgaccc ggcaacggtg ctggcgctgc aacgcaccgc
    40261 cgggaatgcc gccgttacgc ggctgttgga agacgggcgg cctcgggacg gagccacggg
    40321 ccaggaaacc gtccagcgcg ccgtgcacgg aggcaccccc ggcgaggtcg tccagcatgc
    40381 ggaagaggag gcgaccggag gacacggcgg gatcaaggac cgggtcggcg ggaaaatcaa
    40441 ggagaagccc acgaacgacg tggaacgggg tttctacgcc gatatgcgcg cgggcaagca
    40501 ccccgccctg gagggggtgg tcccggattc ctacaccgcc gagcaggtgc agacgatgga
    40561 cggtgaaaag gggaagggcg acgactcgac ccacatctac atcgacaatc tgacgcacga
    40621 catgaagatg ccgaaggtcc tcgacatcaa ggtgggggaa agcaccgcga gcaaacagga
    40681 gttgctcacg tcgatgtcga aggccgacgc ctggaagaag aagatgaaac tgaaggtcgc
    40741 cgacaaggtg accggctccg cggaccgcgg ctatcgagcg gtcggcggca ccggcctcaa
    40801 aggaaagagc cgacgcgcca tcggccgcga gtccgagcag attgtgcagg gcatttccgc
    40861 ggatcccagc gtctacgacc tgctggtgga gcagttgacc caggtcagga cggccgccga
    40921 gaactccggc ctcgccttca tcgcggcgag cgtactcatc gcggtggacg agcagccggc
    40981 gacggagagc ccggcggcca cggcgaaact caacctcatc gacttcgcgc acaccttcgg
    41041 cccggagcag ctgagcgagg agcaggtgaa gaagtaccgc acccgtttcg acaagggaat
    41101 ggcgaggctg atcgcggacg taaaggcggc cggcgcggcc aagaaggagg ctggggagga
    41161 ggccgacgcg tagtgggcca aggccaacgc ccggacgccg cacggcagga aggccattca
    41221 gccggaacgt cgactgaccc tgggtcagcg caggccggtc gccgcccatg ccatgagggc
    41281 cgcgaagtcg tcgcccgtaa ggccgcatcg gggatcgacc cgatgaagca atgcgggacc
    41341 ctcgtgatgc agcggtccat ccacatccac caacagcact gggcgcacca gcccaccccc
    41401 ctctgaccac cgcgccatcg cgccacccct tacgacaagc tcgccgcccg cttcgcagcg
    41461 accgtgctgg tcgcagccct caacgaacgg ctgcgaccag cactttcaca gcaagccctg
    41521 aaggcactcg cttctagtac gacaggtcct tctggtccgt gatcaggcga ccggcgatgt
    41581 gcaggttgcc gtcggagtcg agcaccgcga tgatcttctt cgtggagccg tggtgggtcg
    41641 tgaagtagat cttgtccgcc tcctgggagg tggagcagtt cgtgttcacc gacagttcga
    41701 tgctcaccgg tgagctgatc aggacgtcct ttttgggcga ggtgggatag acctggttct
    41761 gccgcagctt gatacggccg tgggtgtcac cctcagtcca gtccgtcgcc agtccgaggt
    41821 cgatgtccgc catgaggctt cctctccagt tccggcgggc cgtccccttc ctgccgcgct
    41881 tcagccgcgt cgttccctga gtgaagcccg acaggacgtg cccgctcgcc agtgaaagaa
    41941 ccacgtgggt cgggtgacct gcgtcacctg agccgatcca gaacctatat aactcgggca
    42001 tccgacggca ccgaactccg taaatatgac tgatttctac gaagttggcg cgatagtccc
    42061 catctggccc atcgggcgtc cgtcggatca gaggtgggac cggcggcacg cttcctgaag
    42121 atcaccggct gagaggagca tcacagggca acggtccatc ggccacggac agttcgagga
    42181 gacttcctga atgctcgaaa cgttgtggac cgtcatcgtg cccgcgttgg tgctgatggg
    42241 atgcaccttg gtgctgacgg aactcgtctg ggtgctcgtc actttgcgga gggtggatcc
    42301 cgaggaccga tggctggacc gagtcgccgg gcggtcccgg gtacgcgtcc tcgcggagcg
    42361 gacgttccac ttggtgttgt gggtgcatgc ccacaccgtc ggcccggcgg tgcgccggta
    42421 tgtgcggtgg ggtgcccgtg ggacgacgcg tcatctgcgc tgggcccggc gcgggttcgg
    42481 tcaggacgcg gagcggctgt ttcctcgttc ccacgcggta cggaccgcgg tgtgggactg
    42541 gtactgcacc atgccgctgg cgggcatcgc gtacgtcatc aaggcatgcg tacttctcct
    42601 ggtcacggtc aacatcggtg ccatcgtgac caagctggtg accggcgtga cgcacctgtg
    42661 ggagaagagc aagcgggccc ccggaggctc agccgcgaac cctgtcgtcg aaggcggtgg
    42721 gagcgagcgg tcggacccgc ttctcgcgct gatggcggcg ctgcgcaggg tgggcgcggc
    42781 gatcgcggac aaggtgggtc accatctgtc ggcgctcacc gaccccttgg gcaggcccat
    42841 ggaggcgatc attgcggccg ccgccctcgt tctgctcgcg atgatgctgt tggcgtcgcg
    42901 cgtcgcctgg ctcgcgctcc ggcagatagc gagaccttcc taccaggatc acggtccgca
    42961 ttacgccgag ccccgcaccc gcttcacatg ggcccggagg ctgctgagtc tgcgggtggg
    43021 gacgaaccgg gagaaccggc cggtagtggt gttggtgaac tgtctggcca gggtgggggc
    43081 cgcccagtcg tatcaccgct ggtcactccg catccgtagt ccgctgacgg cgccgcgggt
    43141 acaactggcg gacgcggaac gggtggtgtg gtcggcgtgg cggacccggc acacggcgat
    43201 ccgcggtgtg ctgcgcgccc agcacaaaga gcacgcggca gaggtggtgg gggcgttgcg
    43261 catgatggag acccggcagg acacagacgc cgaccgaggg caggcattcg aggacatggc
    43321 gcggatgctg gcgaagatcg ccgagcgata cgcgcagggc cgcacccttg cgctgttgga
    43381 ccccgaagac ctcaccggcg cctcccgggc ggtcaatcgc gagtggatac gcatggtcat
    43441 cctcggcgtc gccgtcatcg ggtcggcagt cggagcctcc gcacttggcg tatcggatgc
    43501 cgcgctcgcc caggtcgtcg gcatcgtcag cctcatcatg gtcggtctgc tgtacgggtc
    43561 ccggctcacg cccaccgacc tcctcgacgt ggtccgtggg cagagccgta agtaagcggg
    43621 aggtcgggct acgggccggg ggggcgggtc aggccggtgg gaagcttcgc cccgtccgcg
    43681 ggcggacgaa cagactccgc gccccctaat aaaccggcag cgccagcagt gtcgaccggt
    43741 tgaggacgaa cagacggttg gcggccgcgg cgagggagcg ggactggccg ccggtgaggg
    43801 cgtaggtctg ggggcggccc tctccgccac gcgggaggcc gctcacgccg gtgtcaccgc
    43861 tctccactat ccagacgctg tttccctgga cgaccggtgg ctgccagggc gggacgacgc
    43921 cggcgaccat catcgggtcg gcggcctggc tgccgttggc gtgcagggaa tgcagtgcgt
    43981 cgcagtccag cgcgtggatc actccgccgg ccacggtggg cgggccccac ccgccggtgc
    44041 cccgtgtggg cggtcgcaac gggttctggg cccatagttc gtggccgtcg gtggccttca
    44101 ccgccgccag gctgttgccg ccgaggtaga cggttccgcc gtcgatggcg ggccgtagtg
    44161 gtcccgcggc ctgccccttg cggatccatg cgcgggagcc gtcgtcggca cggaccgcgg
    44221 ccacgtcccc cgtctccgtg cagagcacca ggtggcctgc gccgagggcc gcggcggggt
    44281 ggccgcccga cagcgtcagc ggtggccgcc gggtccagcg caccttgccg tccgtcccca
    44341 cgcagcgcag gcggccgtcg gaggtcagca ggtagacggc gtgcgcgtcg gcggccagca
    44401 aggcgccgac ctccgcgtcc accgtccagc ggggggagcc ggtggcggcc acccaggtgc
    44461 gcagggtccc ctcggcgtcg gcggcggcca ccagccggtc gccgatcgac aggtatccgg
    44521 cctccgcttt cgcctcgtcg gcccgccacc gctcccggcc gtcggtgacc cggcgggccg
    44581 cgatgccgcc gccggaggcc gcgtacacca ccacgtcgcg caccggcagc ggggccggtg
    44641 acgcggcgtc ggcgacgtcc tggatggggc tccacagcgg ttccggggag ccttcggcgg
    44701 agccgagcgg tgcagcccgc acctttgcgg ccggggggga tgtcgaaggg gtcggacggg
    44761 gcgtcagcag gggtgagcca ccaggcggtg ccgccgcccg ccgcggccag gagcgctcca
    44821 ccgccggcgg ccgcgaccag cagccgccgc cgggtgaggc agggtgcccc gcccaccgcg
    44881 ccgccgtcgg gggcggccga ggggccgggc ggacgggctg tcagacggcg ggcggtcgct
    44941 tcccgttgcc ggatctcctg ccccaacggg ccggatttcc atagccgttc gggctgccgc
    45001 ggggccgccg cggcgtcggc gacctgggtg ggctgcgggc gggccttcgg gtccttggcg
    45061 aagcagggcg tgatgaggta gcgcaaggcc tccggaacgg cggagaggtc ggggctgccg
    45121 tgtacgacct cgtacaggac ggcggtgacc tcggcgccgg tgtacggcgg acggccgctc
    45181 gcggcgtagg cgaggaccgc gccgagggag aagacgtcgg ccgccggtcc gacgcgctgc
    45241 ccgaggacct gttccggtgc gccgtagccc ggtgtgaccg ggatctgtcc cgtacgggtg
    45301 agggtcaggc cgtgctcggg gcgggcgatg ccgaagtcga tgagtcgggg gccgcgcgag
    45361 gtgaggacga cgttgggcgg cttcacgtcc cggtggacga gccccgtggc gtgcacatcc
    45421 tggagcgtac gggccaggga ccgcgccagc tcccgtacgg cggcgtcgtc gagcggcccg
    45481 aagcgcgcga cggcgtcgtc cagcgtcggg ccggccagga actccgtggc gatccacggc
    45541 ctgccgctct ccagttcggc ggccaggacg cgcgccacgc cctcactggt caccgcctgc
    45601 gcggtccgcg cctcccggag gaagcgctcg gccaggtgcc cgtcatgggc gagttccggc
    45661 agcaggacct tcacggcggc ggggcttccg gtggcgtccg ctccgaagta gaccttgccc
    45721 atgccgccct ctccgaggac gccgtgcagg cggtaggggc ccaggcgcag cggatctccc
    45781 tggccgaggg gtttcacagt cggtcgtctc ctggatcgtg gagtggaagg gcgggtcggt
    45841 tctgggccgg gccggccgtc aggcgagcgg gagggcgatg gtccgctgtt cctggcggac
    45901 gtacagccgg ccgcccttgg ggtcggcggt caggaccatc gggttggtct cgtacgtcca
    45961 gacggcttga tgggtgcgca ggtcgatggc gcgcaggccc ttgtcatcgg cgcagtaggc
    46021 ataccgcttg ccgaccgccg gggccacgtc ccgcttgttc ttccttccgg acagcccctt
    46081 ctcctgccag ttcagcgtgc cggaggcggc gtcgacggcg atcagtccgc gatccgcctc
    46141 ggtgcagtag acgacgccgt cgtggacggt gggcgcgccg tagcgccgtt cctcgcccgc
    46201 gctgtcaccg acgtcgcggc cggtcccgaa gagccacgcc agctcgccgt cggacagccg
    46261 gcgggcggtg aggtgctcgg cgcctatgta gaggttccgg tcgtcgagga ccaactgggg
    46321 cggcacggtg cccgcgaacg tctcggagag cctccacagt tcgcggccgt gccgcgtgtc
    46381 gtgcacggag aggcggatga acttcgagcc gaaccccggg ctcccgcaca gcaccacccg
    46441 ggagcccacc acggcgccgc ccagcgcggg cggagtgccc acggtctgtg ggccttccac
    46501 cgggctgcgc cagcgctcct tgcccgagtc caggtcggcc gcgaccaggt accagcgtct
    46561 gccggaggca gcccgggcca ccaggtaggc ggttccgtcg gccacacaca gcagctggtt
    46621 gtactgctcc ttgccggtga acgcggagag ttccaccagg ggtttgccca gttcgccgtt
    46681 gctctgcgag acctcgcaca ccgccagggc cgcgcccgcc tccttgtacc cccgcagggc
    46741 gtagatacgg ctgccttcgg tgaccgagcg ccaggggtcg gagacgttcg cctgccaggt
    46801 cgactcgccc gattcggcgt tgatgccgca cagcacgatc cccgcgcgca tggccaggtt
    46861 gcggcccacc cgcatcacct cgcccccgga gtcggggcag cgcagaccgg cgctccacag
    46921 cggtgtcggc ggcttcggcc ggtcgacggc gtccttcttc gtggcgccgc caccttcgcc
    46981 ggagcccgcg agcagggccc agcccccgcc gccgaggagc ccgccgccca tgagggcgcc
    47041 cccggccacg gacagcagcc gccgccgcga gaggcccggc gcgggggcgg ccccggccgg
    47101 cggcacctcg gcgggcgccg gcggcggcaa gcggtgcggt ggctcgcgcc acacctcgtc
    47161 gctgcgccgg gagatctccc gcagcaccgc gtcgggcagc agctccgcga agccgccgcg
    47221 gtcggccggg gcaagcccgt tggagcccag cgcggtacgc agctcagtgg tggacggccg
    47281 gtgcgcgggg tccttggcca ggcagcggac gagcaggggg cgcagcgtct cgggcacccc
    47341 gcccaggtcc ggctcgccga accggacgcg gtacagcagg tcggtgggcg ccccgccgcc
    47401 gaacggaccg cgaccggtgg cggcgaagac cagcaccccg gccagcgcga acacatcgcc
    47461 cgccaccgcg tgttcctggc cccccgcctg ctcgggcgac atgaacgccg gtgttcccac
    47521 ggcaccgccc acgctcgtca gatgctcgtc gccgaaggcc cgggcgatac cgaagtcgat
    47581 gatccgcggg ccttgcgcgg tcaccaggac gttggacggt ttcaggtcgc ggtggaccac
    47641 ctccgaccgg tgcagctgct ccagcccggc ggcgagtgcc gcgccgaggg cacgcacggc
    47701 cgcctccggc agcggcccgc ccgcttcgac ggccgtgtcc agcggcgggc cgaggacgta
    47761 ctccgtcgcc agccacgggg tcggtgcctg cggatcggcg tcgacgacca ccgccccgtg
    47821 cgcggagccg atgacgcgtg ccgcgtccgc ctccagccgg aagcgggtcc gcagggtggt
    47881 gtccgcggcg agacgggtgt gcagcgtctt caccgcgacc gtgcggccgc ccgccgaacg
    47941 ggccaggtag acggtgccca taccgccgcc gccgaggcgg gcgaggatcc ggaacggccc
    48001 gacggcgtgc gggtcgtcgt gcagaagtgg ggagatcatg gcctcagcgc tcttgggtgg
    48061 ggagtgcggt ggccaggacc tccgccgact gacgggacaa cgcctcgacg atccggccgg
    48121 gcagcgacac cggctccgtg gcaccggcca gcgcgccgta cgccgcgccc ggcagcaact
    48181 ccgccaatac tctcgccggt tcgggccggt cctccggggc gcgcgagcgg cacgccgtga
    48241 cgatgtcccg cagcccggcc gggatctcct gccgctcggg cacggtgtgc ccggtcgccg
    48301 cgtaggccag tacggcaccg agggcgtaga tgtccgcggc ccggtccgcc gcgccacccg
    48361 ccgcgagttc gggagcgagg cagccggtct ccagcccggt cgcctgcgcg ggggaagcca
    48421 ctgccaccgg atgcgcacgg gtcgccccga agcagcccag cagcggcccg caggcggtca
    48481 gcagcacgcc cgccgggcag ataccgccgt gcacgaggcc caggacgtgg gccgaggcca
    48541 gagcttcggc gagcgtgccg ccgagcatac ggaccagcgg ttcgggcagc ggtccgccgt
    48601 acgcggccag ggcggcgggc agcggcagca caggccggta gggcgaggcg taccagggga
    48661 aggccggcgt ccccccgagc tgcgtcaccg gccagaaccc cggctgggtc agccgggccg
    48721 cctgctgcat ctcatccgcc caccgcgccg ggtcaccgcc ggccggcggc aggcacacca
    48781 ggacggtgtg cccgccgtcg acgctgcggg ccagatatcg acgctcggga acgccccgac
    48841 tcccctcggc gtcaagacgc gccaacgcca caaaatcccc gatccgcgca ggatcgtcct
    48901 gccgcagcct ctccactcgg cttctccccc gtcaggctcg ttagggacgt gagcctatat
    48961 acggcgggga ggcgggtcgg caggggggcg gcgtgcggga cgccgggtgc cgtggagggg
    49021 gcaccggggt cgggagtccg gccccgtgtg gtgggaccgg cccgccactc ctacctctcc
    49081 tgcgtctcct acgtcgactt ccgataggcc cggaacgccc gggtggcaag gaagcccctg
    49141 acaaggaccg ccgccgcgag cagccccagt cgcgcccaga ccatgctcca gtcggcgtgt
    49201 acgagcatcg cctgccgcgc cgccgcgacc gcccattcca cggggttgca cgcggcgacc
    49261 cgccccaccc agctcggagc caggtgcagg tccatcacgg cagagctcag gaacatcagc
    49321 ggcagcgtgg tgaactggga gatcgcgatc agcgtggcct gctggcgggt cagcagcgcg
    49381 acggcattgg acagcgccga aaagatcagc gccggcagca ccgctgccag gaccgtgacg
    49441 ccgatcccga cgacgccacc cgggaagcgg gcgccggcga tcagcgcgat gaccaggaag
    49501 gtgggcatcc gccgcagcgt ccgcagcaga caagaggttg tcctgcggtc cgggcgtgcc
    49561 aaatggggcc tgccgacagg gtttcggcag gccccgggct cggtgctcag cagttggtgc
    49621 cgaggacctc accgccgttc ggccagaggc cggtggtctg gtagcagtgg ttcttgtcgg
    49681 cgctgaggtc gtacaggtac tccttggcgc caccgttgcc catggcgaag gtcacggtcg
    49741 ccgtggcacc cgttgcctct tcggggaagt acgccttcca cgtctgtccg accggcttgg
    49801 acgtgtggca gtagttcttg ctctcgatgc cgtccgggcc cttccactgg tagcaggtgt
    49861 cgaccaggaa gcccgaattg ttcgagaact gaatgtagtt gccggagctg gcggaggcgg
    49921 tgggtgccgc agcgaccgta cccatgaggg tcaggcaggc catggcagca atcgtcatcg
    49981 acttcttgac agcgcgcacg ctggaattcc tttccttgtc ccttactcgt ctccgagaag
    50041 ggtcagcagc tcttctcgtt gatggacggg ccccacgtgt aaccgctcag ctcgtagcag
    50101 tggttactct tcaagtcggt gatctgcggt gcttcgagat cgccgatctg ctgaccgtgg
    50161 acaagcaccg tgacctcgac gccggtggca tcggcgggaa tgtccacgcc ccagtcctgg
    50221 ccgatggcct tgttgtcgtc gcagctgtcc ggagtcgccg aaccctgcca cttgtaacag
    50281 gtcttggcga ggaaccagcc cttgttggag aacccgatgt gacccgagtc ctgggcagcg
    50341 gcaggcgacg ccgttacggc cgtgccaccg agggcgagca gcagcgtggc gacaccgtag
    50401 gccatggatc gctttgtctt ttgcacggga gtacctttct gagagggaga aaactcagcg
    50461 accgttcaac agcttctggt cgcacgtgac aatgtcctgg cctacccgct tcccgccttg
    50521 gccgggagtc tcggtacgga gtccggtgat ctttgcgccg ccaaactttc cgccctggat
    50581 cgacacgtcg gtgaccttgc ggtccatgtc gtaacccatc ttgagcattc ccttttggcc
    50641 gggcttcaca gtgatgccca cagcaccgga gctggtttcg gtgtgggact gggtgaatcc
    50701 cgcactggca ccaatgccca gtcggtcctt gaccagggtg acgtcgacac tggcgccgat
    50761 gttccacccc caggagaagg tgtggagtgc cgtgatcgtc tgggtaatgt cattaccgtt
    50821 cggagcacag ttgtcgatcg gcccggtacc caggtcctgg ttctcggcgt cataccattt
    50881 ggtgacctgg ccggcgtcct gagtcgtcgt ggaggcacac gaaacggaga ggttgccgca
    50941 ctgctggagt gcttccagaa catcggcctg tcgggtcagc gtggtgccgt tgtcgtactt
    51001 gacggtcgcg cttccctcgt tcagccagtt gtcggtgtgg ccgttgatct cttgcgggga
    51061 cgccgcggat gccgtcggca cagccacggc aagcgccatc gcggacgcgg ccgcggcgat
    51121 tcctgcccgg taacggaagg tcatgagact ttcgctttct ctggcaacgg gagccttagg
    51181 gctcaagggt tgtgtgaggt gccggcacgt gccggtttca gcaaccgact tccaggagct
    51241 tcgagttgaa ggcggtcccg ctcacctcga cgcagcggtt cttgtcgggg gtcacggcga
    51301 tgctgtccga gggggattcc caggggaagt tcttgaggtc gatcaccact tgggtggtgt
    51361 tcgccggaac ccccaccgag agcgaatcgc ccatcgggcg ggagatgttg cagtagttct
    51421 tgtcctccgc gcccacgaac gtgtagcagg tggtggcggc tatcgcggcg ttctgcttga
    51481 tctggatgtg agtgccctcc gccgcggacg cagtggtggc gaatgccccc agcggcaggc
    51541 aggcgccggc tacggtggcc aggccgaaca gaaccttgct acgcctcttc atgtgactcg
    51601 atcctttctc gaaaattcac gaaggcgaca ccgtccgccg cacaacccgt ttccgggacg
    51661 cccctcgtgt tcgcgtcatc agtgatggtg tgacagttcc cattgttggc agccaatccc
    51721 tggccgagaa cccctgtttt ggctatggcc ccatagccaa agccatgaga catcgggcgg
    51781 cgttcgcctg cccctctcgc catgtggtgg gcaatgccct tccgcatcaa gccccttgcc
    51841 gggatggaga gtcagctatt ccttgagatc gaagagaagc tgcgcgaaag cctcttccac
    51901 acaggagaat ttccggccga ggaggtgcgc catcacgatg gggtggctcg gcagcgcggg
    51961 gaccaggtcg accaacgcca gtcgtccatc ccgcacttct tgcgccacac agtgccagga
    52021 catgagactc gctcccagcc ctgcggacac cgcgagcttg agtgcttcgt tcccccacac
    52081 ctctcccttg tcgacgggct gaatgttcca gcgccgcagg gcggtgttct gtaggtcgcg
    52141 ggttgccgaa ccgctttccc gcagcagcaa ccgcttcgtt gccacgtcct ccgccgtgac
    52201 ctgacggccg gccagcggat gttcgccgcc cacaacgagg acgagccgtt cggacagaat
    52261 gggctcgatg acaagtcccg gcgcagtcgg ctcgccatcg agcagcgcca taccgaccac
    52321 cccgtcgata agctgctgcg tcacctgctc cattccaccc gtgtggatgt cccatcgcag
    52381 tccgggaatc cgggcggtga gacgggcgag tacggacgga accagaatgg cggccgcgtc
    52441 gttggtggtg gccacccgca gacggggctc ggaggaagac accgtcagtt gtacggcgat
    52501 cagcgcttct tcgacgaggg gcatgaggcg ttgggcatac gacaggaagg tctcgccctt
    52561 ggcggtcagc cggatacgcg cccccgaccg gtcgatgagg gtggcttgaa gagaggcttc
    52621 caagcgccgc acctggttgg agaccgacgg ctgactcata tacaacttcc gtgcggcagc
    52681 ggaaaatccc ccgcactcca ccacggcgac gaagatctgt agacgacgta ggcacagtgt
    52741 gttcacgtat cggcctttcg tcggcccttg ttcaccatgg gtatgcagct ggtccgtcgt
    52801 tcgtctgtct ctgttaaccg gcgcttgcgg tggagttcat cgagcattgc gtccaagtcg
    52861 ccctcgttca gggccaggtg atccttggac cggccggagc gcggagcgtg ggaaatgaag
    52921 acggagctcg tgcccctcac gccgtcattg ccgccgccgc acagagagat aggcaccagc
    52981 acgcggacgt cggttaacga cgcaagggga acgcggagcg cagaggtgcg gggatatggg
    53041 ccacggaggg gggtttgcgt ggtcatgagg tccatgcttg gaaccgcatg taacggtttt
    53101 tctgtcgcta gatgatgaga acgtaacaat gcttcgaaaa agcgcgacgt ggtggcggga
    53161 gatggcggcg acggcgtcgg cgccatcaac tccacctggt gcagttgaat tccgaacgag
    53221 cgcttcgtag ttgacgccgc gccagctgag gattgtcgcg gggcacccga cggccccgcc
    53281 gcctcccgat accccgcccg tcagctcagc ggagcacgcc ggcgccaccg gcccttcacc
    53341 ccgc
//
