LOCUS       NZ_CP048852            21612 bp    DNA     circular CON 29-MAR-2024
DEFINITION  Bacillus tequilensis strain EA-CB0015 chromosome, complete genome.
ACCESSION   NZ_CP048852
VERSION     NZ_CP048852.1
KEYWORDS    RefSeq.
SOURCE      Bacillus tequilensis
  ORGANISM  Bacillus tequilensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4012371)
  AUTHORS   Cuellar-Gaviria,T.Z., Ju,K.-S. and Villegas-Escobar,V.
  TITLE     Genome sequencing, annotation and comparative genomic analysis of
            Bacillus tequilensis EA-CB0015, an effective biological control
            agent against Pseudocercospora fijiensis in banana plants
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4012371)
  AUTHORS   Cuellar-Gaviria,T.Z. and Villegas-Escobar,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2020) Biological Sciences, Universidad EAFIT,
            2088, Harwitch Rd, Upper Arlington, OH 43221, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-DEC-2019
            Assembly Method                   :: Unicycler v. 0.4.8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 465.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012225885.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 06:36:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,249
            CDSs (total)                      :: 4,128
            Genes (coding)                    :: 3,960
            CDSs (with protein)               :: 3,960
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 168
            CDSs (without protein)            :: 168
            Pseudo Genes (ambiguous residues) :: 0 of 168
            Pseudo Genes (frameshifted)       :: 118 of 168
            Pseudo Genes (incomplete)         :: 99 of 168
            Pseudo Genes (internal stop)      :: 51 of 168
            Pseudo Genes (multiple problems)  :: 75 of 168
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:17:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3657130
            Orig. end                         :: 3678742
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048852.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Valeska Villegas-Escobar
            Carrera 49 # 7 Sur - 50, Medellin, Colombia.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="8"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(126..140)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(218..3904)
                     /locus_tag="G4P54_RS19265"
                     /old_locus_tag="G4P54_19215"
     CDS             complement(218..3904)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="G4P54_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19215"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_167873557.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     HDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRSVLINLWREALQAHQNPLDAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFMEYAKQYTD
                     FPSLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWNEQTNEFAIPQGTMGSRWDG
                     QQKWNLHMIDEDTGEPIEPRLSVLGIEDEISAVRIPYFSNDGNKVLERDLPIKKLDLNG
                     EEVCVTTVFDLILANYGVNRGIGQQSAVSYDDPEPFTPGWQEQMTGIKKEAVIKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIANAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIASSSRYKHHAD
                     YNVLAARLGWLPSYPTFDKNGIDLYKEAEKAGAETPEDVGAYVASQLQEKKLKFAIEDP
                     DNEANFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVEMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPYTGLKPSGTKGMSWSIAEEYESLKKRLGEITS
                     DSVAKGCPDISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLELKDLAEEREEECF
                     TFEQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAADTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3970..3985)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3994..4007)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3994..4008
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(4053..4064)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            complement(4087..4563)
                     /gene="arfM"
                     /locus_tag="G4P54_RS19270"
                     /old_locus_tag="G4P54_19220"
     CDS             complement(4087..4563)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="G4P54_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19220"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_167873558.1"
                     /transl_table=11
                     /translation="MKRCDYLLFLKQLPMFKEVPLSIVETLLKNGTFIRGSSDQSPSFL
                     YSQSVYIVLKGSVRFMDSRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFIKVNATSDIL
                     ILNIPYCIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAESGS"
     misc_feature    complement(4621..4636)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4707..5426
                     /locus_tag="G4P54_RS19275"
                     /old_locus_tag="G4P54_19225"
     CDS             4707..5426
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="G4P54_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19225"
                     /product="YwiC-like family protein"
                     /protein_id="WP_167873559.1"
                     /transl_table=11
                     /translation="MKVLVPKQHGAWAMLLIPFLLGMVKGGPVLWHIPLFLGWLFLYLA
                     VYPITLALKRKQLKPYQKWIYAYGFPACCFLMISVFHKPPLIWIGVTLVPLFLIHMYFA
                     RRKNERALMNDIAGVLFFCSGGLASCWLGTGILDGWAWFILSQSALFFIGSSFYVKSVI
                     REKRNRGFAYWSWGYHLLLPFLSALLGAGWAFLAFIPSSLRAWFFHGRDWPAKTIGILE
                     IVNAGFFFAVMCIFITR"
     gene            complement(5456..6172)
                     /gene="fnr"
                     /locus_tag="G4P54_RS19280"
                     /old_locus_tag="G4P54_19230"
     CDS             complement(5456..6172)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="G4P54_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19230"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_024713845.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSSHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKQGVISIDESGKIILHKLDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7460)
                     /gene="narK"
                     /locus_tag="G4P54_RS19285"
                     /old_locus_tag="G4P54_19235"
     CDS             complement(6270..7460)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016937598.1"
                     /locus_tag="G4P54_RS19285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19235"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_167873922.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMISFILLLFPVFWISIANSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAITTFAAPVIAQAAGWKATVQ
                     MYLVLLAVFALLHVLFGDRHEKKVNVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLAEHFGLSPADAGLRTAGFIAVSTLLRPAGGFLADKISPLRILMVVFAGLTLS
                     GIILSFSPTIGLYTFGTLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQEKMKTHTERNSQSLDS"
     misc_feature    complement(7524..7539)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7594..9264)
                     /gene="argS"
                     /locus_tag="G4P54_RS19290"
                     /old_locus_tag="G4P54_19240"
     CDS             complement(7594..9264)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="G4P54_RS19290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19240"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_167873560.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARIAKKAPRQIAEEIVASFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     TGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNDNPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSPIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9261..9689)
                     /locus_tag="G4P54_RS19295"
                     /old_locus_tag="G4P54_19245"
     CDS             complement(9261..9689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="G4P54_RS19295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19245"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_167873561.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNEEVIEFRTTGFYHVKQQKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLIMRSGAVKMNQRFITGASTIAKYKMSFGELELETSTKSIQ
                     SDLGEEKGRISIAYDMHVGDEQQHLHNMTITYEGGTHA"
     misc_feature    9869..9883
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.54"
                     /tool="antismash"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            10001..10132
                     /locus_tag="G4P54_RS19300"
                     /old_locus_tag="G4P54_19250"
     CDS             10001..10132
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="G4P54_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19250"
                     /product="subtilosin A family bacteriocin"
                     /protein_id="WP_024713849.1"
                     /sec_met_domain="Subtilosin_A (E-value: 1.6e-27, bitscore:
                     93.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAIIVENKGCATCSIGAVCLVDGPIPDFEVAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAIIVENK"
                     /locus_tag="G4P54_RS19300_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="G4P54_RS19300_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAVCLVDGPIPDFEVAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAIIVENK"
                     /leader_location="[10000:10030](+)"
     misc_feature    complement(10171..10187)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.97"
                     /tool="antismash"
     misc_feature    10187..10200
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.48"
                     /tool="antismash"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="G4P54_RS19305"
                     /old_locus_tag="G4P54_19255"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="G4P54_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19255"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_167873562.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1070.2, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 7.3e-30,
                     bitscore: 101.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.1e-07, bitscore: 27.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1e-43, bitscore:
                     147.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 9.5e-06, bitscore: 23.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.4e-22, bitscore: 76.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.2e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLLNKQVIQLGNQAGR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVPIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMARKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMAYEQHVIDEFSDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_G4P54_RS19305_Subtilosin_rSAM_RRE.1"
                     /evalue="5.00E-32"
                     /identifier="RREFam018.1"
                     /label="G4P54_RS19305"
                     /locus_tag="G4P54_RS19305"
                     /protein_end="97"
                     /protein_start="5"
                     /score="101.1"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLLNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="G4P54_RS19310"
                     /old_locus_tag="G4P54_19260"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="G4P54_RS19310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19260"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_024713851.1"
                     /transl_table=11
                     /translation="MSPSQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /locus_tag="G4P54_RS19315"
                     /old_locus_tag="G4P54_19265"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="G4P54_RS19315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19265"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_167873563.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEHVDLQLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEANAGMPQKTSDQLKTQRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSTYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEDTDLRREFFEVIGHE"
     gene            12495..13805
                     /locus_tag="G4P54_RS19320"
                     /old_locus_tag="G4P54_19270"
     CDS             12495..13805
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="G4P54_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19270"
                     /product="bacteriocin biosynthesis protein AlbD"
                     /protein_id="WP_167873564.1"
                     /transl_table=11
                     /translation="MSNLFPTMSLLFKQLYSRQGKKDVIRIAAGLTILAVFEIGLIRQA
                     DIDESVLGKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCQLPISSRRFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLVWLGRFSFFTVYSIIFGVVLSNHIVKKKN
                     WMFLLHAAIFACVCLSAAFAPAITIPLCAVHMLWAVMIDFPVFLQAPPQQSKMHSFLRR
                     SEFSFYKREWNRFISSKAMLLNYVVMAAFSGFFSFQMMKTGIFNQQVIYIVVSALLLIC
                     SPIALLYSIEKNDRMLLITLPIKPRTMFWAKYRFYSGLLAGGFLLVAVIVGFISGRPIS
                     ALTFVQCMELLLGGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFIATLAG
                     AAVSLAVIPIAGLIIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /locus_tag="G4P54_RS19325"
                     /old_locus_tag="G4P54_19275"
     CDS             13795..14955
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="G4P54_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19275"
                     /product="insulinase family protein"
                     /protein_id="WP_167873923.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 7.6e-06,
                     bitscore: 24.0, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAHLK
                     QQIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYDKNLHVDALIKTFADMSFPS
                     SLAADAVEKAKDELLLKIEKKFTDPFSYSAARLAEEAFGNPMYGTAMFGRKDRIQAIHP
                     HRFLDAADFIVDLLSQHKQLNILGQIQACDIPKQTAQATSVTAGRILVNRQFFETETRS
                     AAGPSVLTLGFDCGEMKNASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKEIPPRVLEAVSHFQVNERELEQAKQFLRNEMLLQFDSPEGL
                     LSYMGILRRFSCTKEDLLDGISVVTCRDVMQFIATIHYIGAHVVRG"
     gene            14960..16243
                     /locus_tag="G4P54_RS19330"
                     /old_locus_tag="G4P54_19280"
     CDS             14960..16243
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="G4P54_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19280"
                     /product="pitrilysin family protein"
                     /protein_id="WP_167873565.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 5.5e-13, bitscore:
                     47.1, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKAFFQHLDERTDIKYTDSGLKIFRLKFPRSHLRLCNVKIDFG
                     SRDVCVRSECGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKMITQEKAVITSEIQTALLNHQLSYHYQLISMLS
                     PASPAAVFPAGRTEDIEALDIRDLQKAYKAAYQPQRMTLFLLGGSEDTEDLLPPRFRIE
                     KRPDHIANRTIISACPPPALSQNIVLGDEEQMENTWTGMQIGALPGQNDLLTAKLYWDI
                     ASRILFQLDSPFFQEIQQTYRLEIDRLSAEAHLYEDGGFLILHSQGAHSSAYIDVASYY
                     VKQRKEQIADWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCKCSFLDMYGIIHEMDT
                     RDFLFLIDALASSNKAVIHVSQKEAIGQ"
     gene            16240..16941
                     /locus_tag="G4P54_RS19335"
                     /old_locus_tag="G4P54_19285"
     CDS             16240..16941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="G4P54_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19285"
                     /product="bacteriocin biosynthesis protein AlbG"
                     /protein_id="WP_167873566.1"
                     /transl_table=11
                     /translation="MKKGTVFTMLLMLAGMAAYSFGWVQAVAEAAAQYVQMIDNDAVRL
                     GLLACIASVLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHRLCSSYANDVK
                     ALRNSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRFHTPLSVSMGLAVLLILYLLY
                     FMRTYLLQLFQHGSLFKKVLAGALTGAGVWWMLSFTISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16947..18341)
                     /locus_tag="G4P54_RS19340"
                     /old_locus_tag="G4P54_19290"
     CDS             complement(16947..18341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014471165.1"
                     /locus_tag="G4P54_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19290"
                     /product="YncE family protein"
                     /protein_id="WP_167873567.1"
                     /transl_table=11
                     /translation="MRNNKLSFKEKAGAAQEECLCFCEEEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVIERCFIETGPEPDEIGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGNGSVSVIRNAEIDQVVYYSDEPDDCPDVSDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPDQRSYVFTVNTGDSTVSVIDADVNTLVSTISLSDIPTDLGVTLNKAYTYVLHRNAN
                     LVSIINNETLTVTQTIPLAGAPRKIQFETGGEFAYILAGGSSIYEINISSQTITNTITV
                     SPAADDFALDPNGQFFYTTNSVIWVVNKYDLNTGQLIESLSNFETPNLIVTPIIGDFAY
                     LENGELRPNGVSVIDLTTFSESSRINRLFDGLITIVFSADGTRAFFLEPYFEAFPENLT
                     VVDTAQHTFITTASLPGVSDLAVTPDNQYIYAAQPDDNTVTVYRTSDYTAVTVIPVGAG
                     PSAIAM"
     misc_feature    18522..18538
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            18571..19716
                     /gene="rapF"
                     /locus_tag="G4P54_RS19350"
                     /old_locus_tag="G4P54_19295"
     CDS             18571..19716
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="G4P54_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19295"
                     /product="response regulator aspartate phosphatase RapF"
                     /protein_id="WP_024713859.1"
                     /transl_table=11
                     /translation="MTGVISSSSVGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGVLDYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFKKAYSMAEAENQPQLMG
                     RTLYNIGLCKNSQSQYEDAVAYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HAYHSKGTAYSQKAGDSIYLSEFEFLKSLYLSGPDEEAIQRFFDFLESKMLYADLEDFA
                     LDVAKYYHERENFQKASAYFLKVEQVRQLIQGGVRLYEIEV"
     gene            19700..19819
                     /locus_tag="G4P54_RS19355"
                     /old_locus_tag="G4P54_19300"
     CDS             19700..19819
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="G4P54_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19300"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_024713860.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFIATNIANAPAHQIEVAQRGMI"
     misc_feature    19845..19854
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(19876..19889)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     misc_feature    complement(19877..19890)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.99"
                     /tool="antismash"
     misc_feature    complement(19950..19962)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     misc_feature    complement(20257..20271)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.93"
                     /tool="antismash"
     misc_feature    20281..20294
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.44"
                     /tool="antismash"
     misc_feature    complement(20282..20295)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.58"
                     /tool="antismash"
     misc_feature    20320..20333
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.96"
                     /tool="antismash"
     misc_feature    complement(20322..20335)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.44"
                     /tool="antismash"
     gene            20349..21137
                     /locus_tag="G4P54_RS19360"
                     /old_locus_tag="G4P54_19305"
     CDS             20349..21137
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115557.1"
                     /locus_tag="G4P54_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G4P54_19305"
                     /product="hypothetical protein"
                     /protein_id="WP_167873568.1"
                     /transl_table=11
                     /translation="MISFFLKRVLKNKEIYFSLFISFVLMIVSYLGILFFHKKINLPYE
                     IHNSPFLSNIAEGNTTSAQLIWILILPLLASLPISGMYREDKNTGFFMNVITKTTKKKY
                     FTVLFGLNFVISFFVIILPLLLNLYLLSMTYPSVNPDGIVNYMDPIVTGGTDLANLYYE
                     HSLIYTLILFALNGMYGAVLSSIGLALSFFIKKKYFVYIIPFLINLIGFTLLNNHYNPL
                     KYIINDGGFLSLDKFIYLNLGVFIATILLYMWGKKRRVLL"
     misc_feature    21451..21469
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.21"
                     /tool="antismash"
     misc_feature    21480..21499
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 20.97"
                     /tool="antismash"
ORIGIN
        1 tttcagttca agcttccctt ttttcaatgt ccagccgcct ttatatttgt cctggtcctc
       61 ccattgcttc gggtagccga tgcccggctt tgtttccaca ttattaaaat acatatattc
      121 cgcaccggaa cggtttgtcc acgtgttttt gcaggtgacg ctgcacgtgt ggcagccgat
      181 gcatttatcc aagttcatga ccataccgat ttgcgcttta atcttcaagc caatcgacct
      241 ccttcagctt gcggatgacg acattcaggt cgcgctggtt ccctgttgga ccgtaatagt
      301 taaagccgta gctgagctgg gcatagcccc cgatcatctg tgtcggcttg acgtgaatcc
      361 ttgtcgggct gttatgggtg cctccgcggt tatttgtcag ttttgtgccg ggcacattga
      421 tgtgacggtc ctgggcatgg tgcataaacg ccattccttt aggaatccgg tgagacaaaa
      481 ccgccctcgc gacgacaacg ccgtttcggt tgaagcattc aatccaatcg ttgtctttga
      541 tatccgtatc cgcggcgtca tctttattca tccacacggt cggcccgccg cggaacagcg
      601 tcagcatcgg cagggaatca aaatacatgc tgtggacgga ccatttatta tgcggcgtca
      661 aataattaag aacgatttct ttgccctctt gatcgggccg tttgcttagg aacggacgat
      721 gctggaggat cggtttaaat gtcgccatcg tttcaccgaa ttccatcatc agttcatgat
      781 cgacataata agattgtctg cccgtcagtg tccgccacgg aattaatttt tctacattcg
      841 tcgtaaacgg agagtacctg cgccctcctt tttctgagcc ggtaaaggcc ggagaggtga
      901 tgaccgtttt cggctgggct gtaatttgtt cgaacgtaaa gcattcttcc tcccgttctt
      961 ccgccaggtc tttcagctcc agatttgtga tgttttcaag tgattcccag gctttcacgg
     1021 cgactttccc atttgaggta gacgataggg ttaaaatcgc ttccgccgcc tgcttcgctt
     1081 cacttatatc cggacatccc tttgcgacgc tgtccgaggt gatttctcca agtctctttt
     1141 tgagtgattc atattcttcg gctatcgacc agctcatccc ttttgtgccg ctcggtttta
     1201 aaccggtgta aggtccgagc gcggtcattt tatgaaaaat atgcttgtaa tcccgttcaa
     1261 cgacttggat gttcggcatc gtttttcccg gaatggcttc acattcgcct ttgctccagt
     1321 cattgatttt gccgaacggc tgggccagct cctgcatcgt gtcgtggagg agcggcgtag
     1381 cgaccacttc tttcaccggc tccatctcga cttcttccgc cagatcggaa acggcttttg
     1441 acagtgcctt gaaaatatcc cagtctgact tcgattccca cggagccgag atcgccggag
     1501 caaaaggatg aatgaacgga tgcatatccg tgctgctgag atcgtgtttt tcataccatg
     1561 tcgccgccgg cagcacgata tcggaataca gcgccgtacc agccattcga aaatcaagat
     1621 tgattaataa gtcgagcttg ccttcgggtg cctgctccct ccatttgatt tcttcagggc
     1681 ggatgctgtc gctgtcgtca ttcatcaaac cgttcgtcgt tcccagcaga tgcttgagaa
     1741 aatattcatg cccttttcct gagctggaga tcagattcgc ccgccatacg aagagatttc
     1801 tcgggaaatt ggcttcattg tctggatctt caatcgcaaa tttcagcttt ttctcttgaa
     1861 gctgtgaggc tacatacgcc ccaacgtctt caggtgtctc cgcccccgct ttttcagcct
     1921 ctttgtatag gtcaatgccg tttttatcaa aagtcgggta ggacggcagc catcctaatc
     1981 gggccgccag cacattgtaa tcggcgtgat gcttgtagcg ggatgaagaa gcgatcggtg
     2041 aagccaagtc actgatcggc tggtcttcgt aacgccactg gtctgtcgca aagtagaaaa
     2101 acgaggttcc gttttgcagc ttgggcacac cctcccagtc ctttgcattt gcgatcgttt
     2161 gccacccttc agcgggacgg agcttttcct gaccgacata atgagcccag cctccgccgt
     2221 ttacgccttg ggcgcctacc aataaaacaa gatttaacac cgcgcggtag attgtgtcgg
     2281 aattgaacca gtggttaatc cccgctccta cgataatcat ggaccggccg tctgtatcga
     2341 tcgcattttg agcaaactct ctcgcaatct taatgacggc ctcttttttg attcccgtca
     2401 tctgttcctg ccagccaggt gtaaacggct caggatcatc ataagagaca gctgattgct
     2461 gaccgatgcc ccggttcacc ccgtagttgg ccaatatcaa gtcaaacacg gtcgtgacac
     2521 acacctcttc gccgttcagg tccagttttt taataggaag gtcccgctcc agcactttgt
     2581 ttccgtcatt tgaaaaatac ggaatgcgca ctgcactgat ttcatcctct attccaagta
     2641 cagagagacg gggttcaatc ggttccccgg tgtcttcatc gatcatatgc aggttccatt
     2701 tttgctgccc gtcccagcgg gagcccattg ttccttgcgg tatagcaaat tcgtttgtct
     2761 gttcattcca gaccgcaggc ttccattgat catgctttgt ctgccgcccg atatccttcg
     2821 catgcagaaa ccgccccgct gtgtatacgc cattttcttt tgacagggtg acgagggatg
     2881 gaaaatccgt gtattgcttc gcgtattcca tgaaacgttc cgtctcttga ttcacgtaaa
     2941 attcctgcaa aatgacgtga cccatggcca tcgcaagcgc accgtcagtc ccttggcgga
     3001 tactgagcca gtcatccgcg aatttagagg attccgcaaa atcgggactg attgaaatca
     3061 ccttggcgcc tttatagcgg gcctccgcca aaaagtgcgc gtcaggcgtt ctcgttaacg
     3121 gaacgttgga accccatgtg atgatatagc ctgaattgta ccaatcactg ctttccggaa
     3181 cgtccgtctg gtcaccccaa atttgcgggg acgctggcgg aagatccgca taccagtcat
     3241 aaaaactgag catagggccg ccgattaacg acataaatcg agagcctgac gcgtggctga
     3301 tcatggacat agctggaatc ggagaaaagc cgacattccg gtcaggtccg tatttcatga
     3361 ctgtatacag cagagaggct gaaatcagct tcagcacctc cggccattca gcacgcacaa
     3421 aaccgccttt ccctcttgcc tgtttatagg acttcgcttt ttcagggttt tcaacgattg
     3481 atttccaagc atcaagcgga ttttgatgcg cctgcaatgc ttcccgccac aaattgatca
     3541 gtacactccg tacgtatggg tatttcacac ggagcgggct gtagatatac catgaaaaac
     3601 tggccccccg cggacagcct ctcggttcga aatcaggcat atccgggcct gttgatggat
     3661 aattcaagtt ttgaccttcc cacgtgacaa ttccgttttt tacataaata ttccagctgc
     3721 aagaccccgt gcagttgacg ccgtgggtgg agcgaacgac tttgtcgtgc tgccatctgt
     3781 ttctgtatac attctcccaa tcgcgatctt cgcgggtggt ttggctatgt ttatttgaat
     3841 ggtgttcgat aggagagaaa taattcaatc tcctaaacaa cggactcatt ttctttttct
     3901 tcatgaaagt tcactccttc cgagtcaggt gatgctaagt tcactataaa cagagacagt
     3961 gtattttctt gtgaactatg tcacacactc tgcttttttc acaaaatatt cacataaggg
     4021 agaaggaagg acttttacag gatgagaagg ctgcgttcat ttaacgatca aaaaacccgg
     4081 ctctatttaa gaaccggact cggcattttc atcttgtgat gtatgcaaat accgcaaaaa
     4141 taattgatag gaacaaaaga cgttttgctg aagcatagcc aaaaaattca tttgcagctg
     4201 gggatgataa gacatcattt ttttaaatat gcaataaggg atattaagaa ttagaatgtc
     4261 tgaagtggca ttgactttga taaaaggcga taaatacagc ccgccttttt catctatcgg
     4321 aaacacatcg cctttttccc acagcgcaac ggttttcgag ccttcaggga gcctgctgtc
     4381 cataaaacgc acactgcctt ttaatacaat ataaacggat tgagaataaa gaaaggatgg
     4441 agactgatca gatgagccgc ggataaacgt tccgtttttc agcaaggttt ccacaatcga
     4501 tagaggcact tctttaaaca taggaagttg tttcagaaat aataaatagt cacaccgttt
     4561 cataggaaag cctcctgtgc taaggatagc tttagtgtag ctcgattgag cctgtacagc
     4621 agtgatatat ttcacagctt gtatgatgaa tgtcacttac cggaaggatg actgcattta
     4681 taatgaaata aaaaaggagg gtttcgatga aggtgcttgt tccgaagcag cacggcgcat
     4741 gggccatgct gctgattcca tttttactcg ggatggtcaa gggcggtccc gttctctggc
     4801 atattccgct cttcctaggc tggcttttcc tttacttggc ggtttatccc attacgctcg
     4861 ccttgaaaag gaaacaactc aagccctatc aaaagtggat atatgcttac ggttttccgg
     4921 cttgctgctt tttgatgatt tctgtctttc ataagccgcc gctcatctgg atcggcgtta
     4981 ctttagtgcc gctgttcctc atccatatgt attttgcccg ccgaaaaaac gaacgagcac
     5041 tgatgaatga tattgcggga gtcttgtttt tttgttcggg cgggcttgcg agctgctggc
     5101 tggggacggg aattcttgac ggctgggctt ggtttattct ctctcaatct gctttatttt
     5161 ttatcgggag ttccttttat gtgaagtcgg tcatccggga gaaaagaaac agaggatttg
     5221 catactggtc atggggctat cacctgctgc tccctttttt atccgctctt ctcggagcag
     5281 gatgggcatt tcttgctttt atcccaagca gcttgcgggc atggtttttt catggaagag
     5341 attggcccgc gaaaacgatc ggcatactgg aaatcgtgaa tgccggcttc ttttttgccg
     5401 tcatgtgcat attcatcaca agataaaaaa acaaggacag cggtgtcctt gttttttagt
     5461 caatattaca aatctccagc ggacaatttt cacactcgat ctcgcatcgc aaatagtcca
     5521 gcttgtgcaa aataattttt ccggattcgt ctattgaaat gaccccttgt tttcggagat
     5581 ctcccagcat acggtttaca ctttctcttg ccgccgcgca aaactttgcc aaatcctgat
     5641 ttgtcagcac aatgttaatc agaataccgt cgcttcgctc caccccatag ctgtttgata
     5701 agcggataag ggtggagtag agcgctccct ttttgccgtg aagaagcaga tccctgattt
     5761 tggactggat tttccggagg tgggagctca tccatttcat aaattcaaat gtcaaagcac
     5821 cgttttggat taattccttt tccagcttgt tcttattaat gacgagcacc tcgccatcct
     5881 ccagcacttt tgcactgagc atataccttg gctcctcggt gaaaagtgtt aattcaccga
     5941 caatatcatg cttttggcag attctaagcg tcaggtcttt tccgtcagat gtcagcttgc
     6001 cgatttcaat gagtcctgat tggatcagat aaagctcctc tgcatccatt ccttcccgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat tgattccagc aattcatgga
     6121 gatcgctgga gatcaaatca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgc gtatgtttat tgtaacgtga cttgatttgc actcacccag
     6241 aaaaaactaa caatcttgtg aatggattat tatgaatcaa gactctgact gtttctctcc
     6301 gtgtgcgttt tcattttttc ctgccaatac atccatatga caaggacaaa gctggctaac
     6361 gctacttcag aaagcgccat aaaaccgatc gcgtattggc ctgttgcctg aaatacactc
     6421 gccaaaatca gcggagggaa aaatcctcct aatccgccca tggcagacac aataccattt
     6481 gcaatacccg cttgcttcga aaaatagaaa ggcacgagtt taaaaacggt cccgtttcct
     6541 atacctgagc agaccgccac cgttaatgtt ccaaacgtat aaaggccgat cgtcggtgag
     6601 aacgataaga taatgcctga taatgtaagt ccagcaaaaa cgaccatcag gatgcgaagc
     6661 gggcttattt tatcagccag aaatccgcct gcaggcctga gcagcgttga tacggcaata
     6721 aagccagccg tccgcaaacc ggcatccgcc ggactcagtc caaaatgctc tgccagaaag
     6781 ttcggcagat agatagtgaa ggcgacaaaa gcgccaaacg taataaaata aaacaggctc
     6841 aaaaaccaca gcacatgatt tcggtaaacg gccttgattt gagttttcac ggaaacattt
     6901 actttcttct catgccgatc accgaacaaa acgtgcagca acgcgaaaac cgccagcaaa
     6961 accagataca tctggacagt tgctttccat cccgcagctt gagcgattac cggcgcggca
     7021 aatgtggtaa tcgcggttcc aatgtttccg gctccgtaaa tcccgttgac gacaccgtgc
     7081 ttttctttcg ggtaatattt cggaagggat gtcaccccaa tggagaacac cgctcccccg
     7141 atccctaaga aaaaaccgcc tgcgattaaa tcaaatagtg agtttgcgat actgatccaa
     7201 aacacaggaa acaaaagcaa gatgaaactg atcataaaca tcagccgcgc gccaaacctg
     7261 ttcgttaaat accctaaagg aatgcggaga agcgacccga ggataacggg aatcgccgtc
     7321 accaaagaga tctcgccttt gctcaaatga atatctaatg tgatttgaga aatgagtgat
     7381 gaaatcagca cccacaccat aaatcctgcc actaagctta atgactgtaa cgataattga
     7441 atgtgttgac ggttgatcat tcggcttgcc cctttcaatg attcaatatc agtcttatca
     7501 tacaaaaacc cggcaaacag gattgtgaaa tacatcacac gttctaccca taaaaaaagg
     7561 acaaagcccg aagactttgt cctttcgtca tcattacatt ttttccggag ccgatacgcc
     7621 gatcagctga agcgcattgt tcagcgtaat ttgcgttgcc ttcattaaag cgaggcgcgc
     7681 gcggcttttc tcttcatttt ctggatcgat gactttctcc gcgttgtaga agctgtgcag
     7741 agcagaagcc agatcataaa tatagtttgt gacacggtgc ggaattcgtt tttccgccgc
     7801 ttccgccact gcctcaggga agccgccgat cgttttcagc aggtcatatt ctttttctga
     7861 ttgaataggg ctgaaatcaa gatccgccgc cggcttaagc ccctgctctt ctccttggcg
     7921 aagcatgctg caaatacggg catgtgcgta ttgtgcataa tacacagggt tgtcgttaga
     7981 tgttgataca gcaagatcta agtcaaaatc catatgcgta tcagcactgc gcatcgcgaa
     8041 gaagtaacgc acggcatcca agccgacttc ttcaatcaga tcgcgcatcg ttaccgcttt
     8101 acccgtccgt ttgctcattt tcattttctc gccgtttttg taaaggtgaa cgagctgaat
     8161 gatttccact tcaagcgttc ctttttcata accaagcgct tcgattgccg ctttcatacg
     8221 cgggatatag ccgtggtgat cggcgcccca tacgttgatc agcttatcaa agccgcggtc
     8281 aagcttgtcc ttatggtacg cgatatcagg aagcaggtac gtgtacgtgc cgtccttctt
     8341 gatcaatacg cggtctttat catcgccgaa cgtcgtggag cggaaccaag tcgcaccgtc
     8401 ttcttcatag acatggcctg tttctcgaag tgcttcaagc gccgtgtcga ttttgccgtt
     8461 ttggtacagt gacgtttcgg aataccacac atcaaatggc acacggaagt tttccaagtc
     8521 cttgcgcagc ttttccagct cgtatttcag gccgtattca cggaagaatg cgaggcgttc
     8581 gctttcctct tcgttgacga atcggtcgcc gtattcctca gcgagacgct ttccgatcgc
     8641 aatgatatcc tcgccgcggt agccgtcctc cggcatcggt ttttccaagc cgagcgcttc
     8701 aaagtaacga acttcgacag aaagcgccaa gttgttgatt tggtttccgg catcgttaat
     8761 gtagtattcg cggctcacat cgtaacccgc ttttgacagc acattgcaca gagaatcacc
     8821 gacagccgca ccgcgggcat ggccaaggtg aaggtctccc gtcggatttg ctgatacgaa
     8881 ttccacttga acgcgttcac cgtttccgat gttcgtttcc ccatatgctt ccccagcttc
     8941 caatacagat ggaatcagct tcgttaaata ttgattattc atatagaaat tgataaaacc
     9001 cgggccggcg atatcgagct tttcgattga agcctttcct ttatcaaagg aagcgacaat
     9061 ctcttcagca atttggcgcg gcgctttttt tgcgattctg gcaagctgca tcgccatatt
     9121 tgttgaataa tctccgtgtg ttttatcttt cggtgtttct aaaacgacat taggaatctg
     9181 gctttcttca gccagtcccg ctttcagaac ggccgctttg atttcttctt tcagcacgtc
     9241 cttcatttgt tccgcaatgt tcatgcgtga gttcctccct catacgtgat cgtcatatta
     9301 tgtaaatgct gctgctcgtc tccgacatgc atgtcatatg cgatgctgat tcggcctttt
     9361 tcttcaccga gatcagattg aattgatttt gtgcttgttt ccagctcaag ctcaccaaat
     9421 gacattttat atttcgcaat tgtggaagct cccgttatga aacgctgatt cattttaaca
     9481 gcgcctgacc tcatgatcag gacttcgcct tcgctcacct tcacaatcgt ttttactttg
     9541 cctaggtcgt gttcttcata ataagataga tacacttttt gttgttttac atggtaaaat
     9601 ccggtagtgc ggaattcgat gacttcctca tttccgtcat cttcgatcac agacttcaca
     9661 tggagtgtta tcggtgtctc ttgcttcatt ttgacacgtc cttttcatca ttccactttg
     9721 acttgaatag tataatcatt cagtttgtaa acttcaactg cttctatctt accatcattg
     9781 ctcattagat ttgaagataa acctcataaa aagcagttcc ttatgagaag agaaaatcat
     9841 atcactaatt gcccagaata aatgttacat ttttctgaaa tctatctttt tgaattcaca
     9901 ttttcttcaa aatatatgta ttgaaatggt aatttaatag ttttatgata aaagcacaac
     9961 gtagatctgc tagaaaaaac aaaaaaggga ggattcaatt atgaaaaaag ctattattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagctgtt tgtctagtgg acggtcctat
    10081 ccctgatttt gaagttgccg gtgcaacagg tctattcggt ctttggggat aaggttctcc
    10141 aacaagggca tagttatttc tactatgccc ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggttatacat acacaattgt ttttcatttg aatcacatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttcagact
    10381 ttgagtactt ggatcttaac aaaacggctt acgagctttg catgcgaatg gatgggcaaa
    10441 aaacggctga gcaaatttta gcggagcaat gcgcggtgta cgatgaatca ccggaagacc
    10501 acaaggactg gtattacgac atgctcaaca tgctcctcaa caaacaggtc atccagcttg
    10561 gaaatcaggc cggccgccac accatcacca cgagcggaag caatgagttt ccgatgccgc
    10621 tgcacgccac ctttgagctg acacaccgct gcaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc ggaagcgctc ggcaccgtgc cgattgagca gttcaagaaa acggctgata
    10741 tgctgtttga caacggtgta ttgacttgcg aaatcacggg cggtgaaatc tttgtccatc
    10801 cgaatgcaaa tgagattctt gactatgtgt gtaaaaaatt caaaaaggtc gctgtcttaa
    10861 cgaacggaac actcatgcga aaagagagcc tggagctttt gaaagcgtac aagcaaaaaa
    10921 tcatcgtcgg catttctctc gatagtgtga attccgaagt ccacgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgctatgtcc gttttcgaaa aaaacatgtg ggaaatccat gatatggccc
    11101 ggaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcagaga tatcatccac cccacaaaag atgccgagca gcaccgcaag tttatggcat
    11221 acgagcaaca tgtcattgat gagtttagcg atctgattcc gattatccct tatgagagaa
    11281 aacgcgcggc caattgcggc gccggctgga agtctatcgt tatcagcccg tttggagaag
    11341 tacgtccgtg cgcgctcttt ccgaaggaat tttcattggg aaatattttt catgattcct
    11401 atgagagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcggt
    11461 tcagcgagca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc ggaaaaatat ttgctcctgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgctttgtca ccatcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tttttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatttattt acgctgattt tcattgccat tgccattctt ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacatgt ggatttacag ttagaaaaag gcgctgttta
    11881 cggattgctt ggggtgaacg gcgccggaaa aacgaccttg attaatacgc tgacaggggt
    11941 caaccgtaat ttcagcgggc gctttacact gtgcggcatt gaggctaatg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca acgatacttc gccgccgatt atccgttgtt
    12061 gtttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 cttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcaa catacatcaa
    12181 tagaagaatt tcagagctgt ccttggggaa caggcaaaag gttgtgttga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtc ttttatcaga aaatgcgcga gtactgcgag gcaggcggaa ccattttgtt
    12361 ttcttcccat ctgcttgatg tcgtgcagcg attttgtgat tatgcggcca tccttcacaa
    12421 caaacagatc caaaaagtca ttccgattgg agaggacacc gatttgcggc gggaattttt
    12481 cgaggtgatc ggccatgagt aacctatttc ccaccatgtc tctgctgttc aaacagctgt
    12541 acagccggca agggaaaaag gacgtcatcc gcattgccgc agggcttacg attctggccg
    12601 tatttgaaat tgggctgatc cgccaagccg acattgacga atcggtgctg ggaaaaacgt
    12661 atatcatact tgcacttctt ttgatgaacg cgtatatggt gtttctttcc gtgacatcac
    12721 aatggaagga atcttatatg aagctgagct gccagctgcc gatttcttca cggcgctttt
    12781 ggctcgctca gagtgtcgtt ctgtttgtcg acacctgttt gagaagaacg ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc tggggcgcaa acattggttt
    12901 ggctcggcag gttttcgttt tttaccgttt actcaattat tttcggagtt gtgctaagca
    12961 accatatcgt caaaaagaag aactggatgt ttctgctgca tgcggcaata ttcgcctgtg
    13021 tatgcctcag cgccgctttt gcgccggcga tcacgatccc gctatgcgct gtgcacatgc
    13081 tgtgggcggt gatgattgac tttcctgtct ttctgcaggc gcctccgcag cagagtaaga
    13141 tgcattcttt tttgcgaaga tctgaatttt cgttttataa aagagaatgg aaccgattca
    13201 tctcctctaa agcgatgctg ttaaattacg tggtgatggc ggcgttcagc ggcttctttt
    13261 cgtttcagat gatgaagacc ggcatcttca atcagcaagt gatttatatt gtggtttccg
    13321 cccttttgct gatctgctcg ccgatcgctc ttttgtactc gattgaaaaa aacgaccgga
    13381 tgctgctcat cacacttccg attaaaccga gaacgatgtt ttgggcgaaa tatcgctttt
    13441 attctggcct gttggcaggc ggatttctcc ttgtcgctgt cattgtgggc tttatcagcg
    13501 gccggccgat ttcggccctc acttttgtgc agtgcatgga attgctgctg gggggagcgt
    13561 ttatccggtt aaccgcggat gaaaaaaggc cgtccttcag ctggcagacg gagcagcagc
    13621 tctggagcgg tttttcaaaa tatcggtctt atctgttttg tcttccccta ttcatagcca
    13681 cgttagccgg cgccgctgtc tccttggcgg ttattccgat tgccgggctg atcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca acaatctcaa tcgccgcgag ctttctgaag
    13861 ccaatcgaaa gcgcggcgga gcctgaagaa gaaacaatct atttttacgg cgcggccgca
    13921 catctgaagc agcaaatcat cgacgctttc ggttatgcgg ccggcagccg cttcatgtat
    13981 tcagcgaatc tcttttttga ccagcagctg aaaacttgcg gaacccgttt gattcacccg
    14041 ttatatgaca agaatcttca tgttgatgcc ctgataaaaa catttgcaga catgtccttc
    14101 ccttcttctc ttgcagccga tgctgttgaa aaggcaaagg atgaactgct gctcaaaatc
    14161 gaaaagaaat tcactgaccc cttctcttac tcagcagcac gcttggcgga agaggccttc
    14221 ggaaacccga tgtacggcac tgccatgttt gggcgaaaag acaggataca agcaatccac
    14281 cctcaccggt ttttagatgc agctgacttc atcgttgatt tattgtcgca gcataaacag
    14341 ctgaacatat tgggacagat acaagcatgt gatatcccga agcaaacagc acaagcgacc
    14401 tctgtgacag ccggaaggat cctcgtgaac cggcagtttt ttgaaacaga gacacgcagt
    14461 gcagcaggcc cttctgtctt gacactcgga ttcgactgcg gggagatgaa aaatgccagc
    14521 gattatatca aaatccagct gatagacgga ttactcggaa agtatggaca ttccgcttta
    14581 ttcaagcatt tccgcgagaa ggacctggca gtctatcacg tcatcacccg ttatgacgtc
    14641 atgaacaatc tgctgcttgt ttctatatgt acggatcagc ttcatgaaaa ggagattccc
    14701 ccgcgcgttt tggaagctgt ctcacatttt caagtgaatg agcgggaact agaacaagcc
    14761 aagcaatttt tacgcaatga aatgctgctg cagtttgatt ctcccgaagg gcttttgtcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag acttgctgga cggcatctcg
    14881 gtggtgacat gccgtgatgt aatgcaattc atagcgacta tccattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggacaagaa agcttttttt cagcatctgg atgaacgaac
    15001 cgatatcaaa tacacagaca gcgggctgaa aatattcaga ttgaaattcc cccgctccca
    15061 tctgcggctg tgtaatgtga aaattgattt tggaagccgt gatgtctgcg tacggtcaga
    15121 gtgcggtgac acgctgctcc cgtatggcac agcgcatttt ttggagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcac ggtgcgcttt taaacgcgtt
    15241 caccacctac accgatacca atttcatgtt tacctcattg ccggatcggc tcagacagac
    15301 gatccccatc ctgctggatg cgttatggaa ccactcattt gataagaaaa tgatcactca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcactc ctcaatcatc agctctctta
    15421 ccattatcag ctgatcagca tgctttctcc cgcctcacct gccgccgtct tccccgcggg
    15481 cagaaccgag gacattgagg cgctggacat tcgcgattta cagaaagcct acaaggccgc
    15541 ctatcagccc cagcggatga ccctgttttt gctcggaggc tcagaagaca cggaagacct
    15601 tttgcctccc cgctttcgaa tagaaaagcg tccagatcat atagcaaata gaacaatcat
    15661 ctccgcatgc cctccaccag ctctttcaca aaatatagtg ctgggtgatg aggagcagat
    15721 ggaaaacaca tggaccggga tgcagatcgg cgcacttccc gggcaaaacg atctgttgac
    15781 ggcaaagctt tattgggaca ttgcgtctcg aattttattt caattagatt caccgttttt
    15841 tcaggagatt cagcaaacat accgtctgga aatcgatcgc ttgtcagccg aggctcacct
    15901 ttatgaggat ggcggttttt tgatcctaca cagtcaagga gcgcattctt cagcttatat
    15961 cgatgttgct tcctactacg tcaaacagcg gaaagaacag attgcggact ggcttcaata
    16021 cggcaaggat tctttgacgg acgccatcat ctatgacagc gattatgtgc gtaagtgctt
    16081 cgaatgggca gccgagtgtg accggtgcaa gtgttcattt ctcgacatgt acggcatcat
    16141 tcacgaaatg gatacccggg atttcttatt tctcattgat gcgttggcat cctccaacaa
    16201 agcggtcatt cacgtttctc agaaagaggc gatcggacaa tgaaaaaagg cactgtcttt
    16261 accatgttat tgatgcttgc aggtatggcg gcatattcct tcggctgggt tcaggccgtc
    16321 gccgaagccg ctgcccaata tgtacaaatg attgataacg atgctgtgcg gctcggtctg
    16381 ctggcttgta tcgcttccgt cctgatgctg cccgcttttc tctatcttca ctatgtcacc
    16441 caatccgtga aaaacatgac agcagctttt cagaaactca cacagtctca tcaaagctgc
    16501 tgcgacttcc agcaacatag attgtgcagc agctatgcca acgatgtcaa agcgctgcgt
    16561 aacagctata aaaacgtccg ccaaacatac gtgatggctg ctgtattatg ccaagtcatc
    16621 atattcggat gcatgttcga aatcgtcaag gccgtccctt tccgctttca cacgcccctt
    16681 tccgtatcaa tgggcctcgc ggtgttactg attttgtatt tattgtattt tatgcggacg
    16741 tacttgctgc agcttttcca gcatggcagc ctgttcaaaa aagtgcttgc gggagcgctg
    16801 acaggagccg gggtctggtg gatgctcagt ttcaccataa gtgaactgct gtttttgatc
    16861 atcctggctg ccatccagca gatcggctca tttatttata aacgattttc ttatcgcagc
    16921 accgcttctc tcgatctatg aaatcgctac attgcaatcg cagacggacc cgcgccaacc
    16981 gggatcaccg tcacagctgt ataatcgctc gtgcggtaca cggtcacggt attgtcgtcg
    17041 ggctgcgctg cataaatgta ctgattatca ggtgttacgg cgagatcaga gacaccgggg
    17101 agagaggcag ttgttataaa ggtatgctgc gctgtatcta cgacagtgag attctccggg
    17161 aatgcctcaa aatagggctc aaggaaaaac gcacgagtcc cgtcagcaga aaaaacaatt
    17221 gtaattaaac cgtcaaacag tctgttaatt cgtgaagatt cgctaaatgt tgtcaaatct
    17281 atcacagaaa cgccattcgg ccttagctca ccattttcca gataagcaaa atcccctatt
    17341 atcggggtga caattaaatt tggtgtttca aagttactta aactttcgat cagctgtccg
    17401 gtgtttaggt catatttatt aacgacccaa attacagagt tggtcgtata gaaaaactgt
    17461 ccgttagggt ctagggcaaa atcgtccgca gcgggtgaca ccgtgattgt attggtaatg
    17521 gtttgcgagg aaatattaat ttcataaatg gagctgcccc ctgcgagaat ataagcaaat
    17581 tctcccccag tttcaaactg gatttttctt ggggctcctg caagagggat ggtttgtgta
    17641 accgttaatg tttcgttgtt aatgatcgat acaagattcg cattcctatg gagaacatac
    17701 gtatacgctt tattcaaggt aacacccaaa tcagtcggga tatcagataa agaaatggta
    17761 cttacaagag tattcacgtc agcatcaatg accgaaaccg tgctgtctcc agtgtttaca
    17821 gtaaacacgt aagatcgctg atccggttcg ggcacaagca caatcgtgcc cgtcaccgat
    17881 aaaggactgc catagaacgg cggaacgaca acaaggttct cgatcgtaat gtcactgaca
    17941 tccgggcaat catcgggctc atcggaataa tagacgactt ggtcaatctc tgcattgcgg
    18001 atgacagaaa cagacccgtt cccttgtcca tattgatttc gcactggtga gacgctgacg
    18061 agaagcgtaa cagttccctg caggcgcact gcgaattgaa caccgatttc atcaggctca
    18121 ggccccgtct caatgaaaca gcgttcaatg acacaagaaa ggctgtctgc attccacgtc
    18181 acgtttgcaa cagcttcagc cggatcaacg acaaacccct caggcaattc aatcggcgct
    18241 tgaaacatcg cttcacggct tgcttcttcc tcgcaaaaac ataaacattc ttcttgtgcg
    18301 gctcctgctt tttctttaaa ggaaagcttg ttatttctca tatcttcact tccttttcag
    18361 acatacactg ctcacgcaga tacaacagaa tatggaaggt atatttgttt gcttgtacaa
    18421 attgtcgggg ataatagtgg atttttgaaa tgatatccgc agacatgcgg tgtaacgaaa
    18481 gaaaacattg cggttttttt gcgcttctca catgaatgat gatgataaaa tatgacatat
    18541 attgaataat gaagggaggg atttgcaaac gtgacaggtg tcatatcttc ttcttccgtc
    18601 ggagaaaaga ttaacgaatg gtatatgtac atacgccgat tcagcatacc cgatgcagaa
    18661 tatttgcgaa gagaaatcaa acaagagctg gatcaaatgg aagaagacca agatcttcat
    18721 ttgtactatt cactgatgga attccggcac aacctgatgc ttgagtatct tgaaccgctg
    18781 gaaaaaatgc ggattgagga acagccgaga ttgtctgacc tgctgcttga gattgataaa
    18841 aaacaggctc gtttaactgg agtccttgat tattacttta attttttcag aggaatgtac
    18901 gaattggatc agcgggaata cctgtcggct atcaaatttt tcaaaaaggc cgaaagcaag
    18961 ttgatattcg tgaaggatcg gatagaaaag gctgagtttt tctttaagat gtctgaatct
    19021 tattactata tgaaacaaac gtatttttca atggactatg cacggcaggc gtatgaaata
    19081 tacaaagaac atgaagcgta taatataaga ttgcttcagt gtcactcttt atttgctacc
    19141 aatttcttag acctgaaaca atatgaggat gccatctcac attttaaaaa agcttactct
    19201 atggcggaag ctgagaatca gccccaatta atggggagaa ctttgtacaa catcgggctt
    19261 tgcaaaaaca gccaaagcca atatgaggat gccgtagcat atttcaaaag agcaatagct
    19321 gtttttgagg aatctaatat tcttccttcc ctgccccaag cctatttttt aattacacaa
    19381 atacattata aattaggaaa aatggataaa gcacacgcat atcatagtaa gggaacggct
    19441 tattctcaaa aggccggaga ttcaatctat ttatcggagt ttgaattttt gaaatcttta
    19501 tacttatcag gccctgatga agaagcaatt caaaggttct ttgatttcct cgaaagtaaa
    19561 atgctgtatg ccgatcttga ggatttcgct ctcgatgtgg caaaatatta tcatgaacgt
    19621 gaaaattttc aaaaagcttc tgcttatttc ctgaaggtgg aacaagtaag gcaacttatt
    19681 caaggaggag tgagattgta tgaaattgaa gtctaaacta ttactctctt gtctggccct
    19741 aagcactgtt ttcatcgcaa cgaatattgc aaatgcacct gcacaccaaa ttgaagttgc
    19801 acagcgagga atgatttaat gttaacaacc ggtaaaaaac cggttgtttt tttaatatag
    19861 aagccaatac aagagtttta ttttaaaaat tttaaattta attaccaaat tattttaaat
    19921 tggttttcta atcaataaac atagtaaatg agacaatttc actaatgaaa aacctgttta
    19981 cttttccttt ttattgaact attatatata agacttaagt tcagtacatc ttcaattgaa
    20041 ggtaaaaaac ggatatccat acgtacttat tttccaacac tgctgctgaa aagagatgtg
    20101 cccgtaaggt ttggcaacta cagctatagt ggtggtatct ttccaagtga ttggagtcct
    20161 gacagcgtaa atcctaaggg aaattacaca gtctattaat acctttctca aaaccaagcg
    20221 atcttacatt gcacaatgta agatcgcttt ttaaggtgaa aataatattc actcttcaag
    20281 attttttatt aaaataaaaa atatccaaaa ctcacacaga gttttaataa aaaataggag
    20341 catcgcacat gatttctttc tttttaaagc gtgtattaaa aaataaagag atttatttct
    20401 ctttattcat tagtttcgtt cttatgatcg tcagttatct aggtattctc ttctttcata
    20461 agaagatcaa tcttccttat gaaattcata actcaccttt tttatcgaat attgcagaag
    20521 gaaacacaac ctcagctcag cttatctgga ttctcattct tccgttatta gcatcacttc
    20581 caatttctgg tatgtaccgt gaagataaaa atactgggtt ttttatgaat gtcataacaa
    20641 aaacaactaa aaagaaatac ttcacagtat tattcgggtt aaactttgtc atttcatttt
    20701 tcgtcattat tttaccatta ttattaaatc tttatttgct atcgatgaca tatccttcgg
    20761 taaacccaga cgggatcgtc aattacatgg accccatcgt tacaggcgga acagacttag
    20821 caaacctgta ttacgaacac tcattaatat atactcttat tctttttgca ttaaatggga
    20881 tgtatggagc tgttctttct tccattggat tggctttatc attttttatt aaaaagaaat
    20941 attttgttta tatcatacct ttcttgatca atttaatagg ctttacttta ctcaacaacc
    21001 attacaatcc actgaaatat atcattaatg atggaggatt tttgagttta gataagttta
    21061 tttatttgaa ccttggagta ttcattgcaa ctatcttact ttatatgtgg ggaaaaaaac
    21121 gccgtgtttt attataatac tttaaaatca acattaagaa tgaagtggct gggtatcatc
    21181 gccgctttac tgctgcagtt aattgctgtt tatttcttct tttatcaaga aaatggtagt
    21241 ggcgatgatt ttgtactgga aaatattttt tcctattggc atctcgtttc tattttatgc
    21301 cctgctgccg tgatattttc tgttttgatt tcatcagatt acttttcaat ttatactgtc
    21361 atccgagtaa acaatgcacc ttatctaaca ttgatatacc tgttcaaaac acttttattt
    21421 tcagcagtat acgggattat cattatgggt gaattgtata ctttatgtgt gttcaataat
    21481 acgggactat tgtctctgac ccctatatct tttatcactc atgtgtttgc ctttattttc
    21541 atttgttatg ttgtttcatt tactttgctg tatttgaatc aaatcattgt agttttttta
    21601 ttcattcctt ta
//
