LOCUS       NZ_JAAUXF010000005     21612 bp    DNA     linear   CON 06-NOV-2024
DEFINITION  Bacillus subtilis strain CH311 CH311_scaffold_5, whole genome
            shotgun sequence.
ACCESSION   NZ_JAAUXF010000005
VERSION     NZ_JAAUXF010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 3641252)
  AUTHORS   Dion,M. and Batard,E.
  TITLE     Sequencing of two strains of Bacillus subtilis to analyse their new
            metabolic properties
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3641252)
  AUTHORS   Sassi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-MAR-2020) Irs2, University of Nantes, 22 Bd Benoni
            Goullin, Nantes 44100, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: OCT-2019
            Assembly Method                   :: SPAdes v. 3.13.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 517x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012030395.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 06:35:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,413
            CDSs (total)                      :: 4,340
            Genes (coding)                    :: 4,197
            CDSs (with protein)               :: 4,197
            Genes (RNA)                       :: 73
            rRNAs                             :: 5 (5S)
            complete rRNAs                    :: 5 (5S)
            tRNAs                             :: 63
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 71 of 143
            Pseudo Genes (incomplete)         :: 90 of 143
            Pseudo Genes (internal stop)      :: 17 of 143
            Pseudo Genes (multiple problems)  :: 32 of 143
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:22:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3145257
            Orig. end                         :: 3166869
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAAUXF010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="7"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(89..103)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(181..3867)
                     /gene="narG"
                     /locus_tag="HC742_RS19290"
                     /old_locus_tag="HC742_19280"
     CDS             complement(181..3867)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="HC742_RS19290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19280"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_167560619.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQEHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAIAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAETPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3933..3948)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3957..3970)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3957..3971
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     misc_feature    3998..4012
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            complement(4085..4561)
                     /gene="arfM"
                     /locus_tag="HC742_RS19295"
                     /old_locus_tag="HC742_19285"
     CDS             complement(4085..4561)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="HC742_RS19295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19285"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4619..4634)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4705..5424
                     /gene="ywiC"
                     /locus_tag="HC742_RS19300"
                     /old_locus_tag="HC742_19290"
     CDS             4705..5424
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="HC742_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19290"
                     /product="YwiC-like family protein"
                     /protein_id="WP_167560621.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKQYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(5456..6172)
                     /gene="fnr"
                     /locus_tag="HC742_RS19305"
                     /old_locus_tag="HC742_19295"
     CDS             complement(5456..6172)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="HC742_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19295"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_014481215.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="HC742_RS19310"
                     /old_locus_tag="HC742_19300"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="HC742_RS19310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19300"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_010886631.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLILLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="HC742_RS19315"
                     /old_locus_tag="HC742_19305"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="HC742_RS19315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19305"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_167560623.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGNRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEQM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="HC742_RS19320"
                     /old_locus_tag="HC742_19310"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="HC742_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19310"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="HC742_RS19325"
                     /old_locus_tag="HC742_19315"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="HC742_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19315"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 8.2e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="HC742_RS19325_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="HC742_RS19325_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="HC742_RS19330"
                     /old_locus_tag="HC742_19320"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="HC742_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19320"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="HC742_RS19335"
                     /old_locus_tag="HC742_19325"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="HC742_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19325"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_015714887.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 4.6e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1e-44, bitscore:
                     150.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.2e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.8e-22, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.7e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HC742_RS19335_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="HC742_RS19335"
                     /locus_tag="HC742_RS19335"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="HC742_RS19340"
                     /old_locus_tag="HC742_19330"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="HC742_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19330"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="HC742_RS19345"
                     /old_locus_tag="HC742_19335"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="HC742_RS19345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19335"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="HC742_RS19350"
                     /old_locus_tag="HC742_19340"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="HC742_RS19350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19340"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_046381398.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPATTLPLCAVHMLWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="HC742_RS19355"
                     /old_locus_tag="HC742_19345"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="HC742_RS19355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19345"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080481011.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.9e-05,
                     bitscore: 21.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRRDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="HC742_RS19360"
                     /old_locus_tag="HC742_19350"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="HC742_RS19360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19350"
                     /product="pitrilysin family protein"
                     /protein_id="WP_167560625.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.3e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIILACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDTQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="HC742_RS19365"
                     /old_locus_tag="HC742_19355"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="HC742_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19355"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_029726080.1"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18320)
                     /gene="ywhL"
                     /locus_tag="HC742_RS19370"
                     /old_locus_tag="HC742_19360"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="HC742_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19360"
                     /product="YncE family protein"
                     /protein_id="WP_134154700.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTGNLSCISEPCLIQTGPEPEDIGVRYAVRVQGAITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQMTVEDLLIVPPFYGSPLTVAGILVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTIVKTIPFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18287..18304
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18360..19721)
                     /gene="ywhK"
                     /locus_tag="HC742_RS19375"
                     /old_locus_tag="HC742_19365"
     CDS             complement(18360..19721)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="HC742_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19365"
                     /product="YncE family protein"
                     /protein_id="WP_167560627.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEQEECLCFCEGEASREAMFQAPIELPEGF
                     VVDPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRN
                     QYGQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIV
                     LVPEPEPVYAFTANPNDQSVSVIDTNTHSVVTTIALPYNPAGIEITPDKSAVFVLHPNN
                     NVISVIDYDTLTVTASILLDQPPRLIRFIPNHEFAYVFTGTAVSVIGIDTLTVDRSIPV
                     EGYDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQ
                     EFFFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGTGVYLHDGFTGNLYSVSPNGAGVI
                     GNVPQSARDFAFTPNGEFLYATHVLEQSITVYNTDDYSVETVISLGVSPGAIAI"
     gene            complement(19718..19948)
                     /locus_tag="HC742_RS22345"
                     /old_locus_tag="HC742_19370"
     CDS             complement(19718..19948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="HC742_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19370"
                     /product="hypothetical protein"
                     /protein_id="WP_024572000.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQQFVQANTLPFHILLYLREQCMSEKEVKE"
     misc_feature    19902..19918
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19951..21096
                     /locus_tag="HC742_RS19385"
                     /old_locus_tag="HC742_19375"
     CDS             19951..21096
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="HC742_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19375"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_167560629.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAVAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21080..21199
                     /locus_tag="HC742_RS19390"
                     /old_locus_tag="HC742_19380"
     CDS             21080..21199
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="HC742_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HC742_19380"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 cctttatatt tgtcctggtc ctcccattgc ttcgggtagc cgatgcccgg ctttgtttct
       61 acattattga agtacatata ttccgcaccg gaacggtttg tccacgtgtt tttgcaggtg
      121 acgctgcacg tgtggcagcc gatgcattta tccaagttca tgaccatacc gatttgcgct
      181 ttaatcttca agccaatcga cctccttcag cttgcggatg acgacgttca ggtcgcgctg
      241 attccccgtt ggaccgtaat aattaaagcc gtagctgagc tgggcatagc ccccgatcat
      301 ctgtgtcggc ttgacgtgaa tccttgtcgg gctgttatgg gtgcctccgc ggttattcgt
      361 cagctttgtg ccgggcacgt tgatgtggcg gtcctgggca tggtgcataa acgccattcc
      421 tttaggaatc cgatgagaca aaacggctct cgcgacgaca acaccgtttc ggttaaagca
      481 ttcaatccaa tcgttgtctt tgatatccgt gtcctctgca tcatctttat tcatccacac
      541 ggttggcccg ccgcggaaca gcgtcagcat tggcagagaa tcaaaataca tgctgtggac
      601 agaccattta ttatgcggcg tcaaataatt gaggacgatt tcttttccct cttgatcagg
      661 ccgcttgctc agaaacgggc gatgctggag gatcggtttg aatgtcgcca tcgtttcacc
      721 gaattccatc atcagttcat gatcgacata ataggattgt ctgcctgtca gcgtccgcca
      781 cggaattaat ttttcaacat tcgtcgtaaa cggcgaatac ctgcgccctc ctttttcaga
      841 gccggaaaac gctggagacg tgatcaccgt tttcggctgg gctgtaattt gttcgaacgt
      901 aaagcattct tcctcgcgtt cttccgccag gtctttcagc ttcaggttcg tgatgttttc
      961 aagtgattcc catgctttta ctgcgacctt tccattcgaa gtggatgata gggttaaaat
     1021 cgcttctgca gcctgctttg cttcacttat attcggacat ccctttgcga cactgtccga
     1081 ggtgatttct cccaatctct gtttgagtga ttcatattca tcggctattg accagctcat
     1141 cccttttgtt ccgctcggct ttaaagcaac gttcggacca agtgcagtca ttttatgaaa
     1201 aatgtgtttg taatcccgtt caacgacttg gatgttcggc atcgtttttc ccggaatggc
     1261 ttcacattcg cctttgctcc agtcattgat tttgccgaat ggctgggcca attcctgcat
     1321 ggtgtcatgg aggagcggcg tcgcaaccac ttctttcacc ggctccatat cgacttcttc
     1381 tgccagatcg gaaacggctt ttgacagcgc cttgaaaata tcccagtctg acttcgattc
     1441 ccacggagcc gagatcgcag gagcaaatgg atgaatgaac ggatgcatat ctgtgctgct
     1501 gagatcgtgt ttttcatacc atgtcgccgc cggcagcacg atatcggaat acagcgccgt
     1561 accggccatt cggaagtcaa gattgattaa caagtcgagc tttccttccg gcgcctgctc
     1621 ccgccatttg atttcttcag ggcggatgct gtcgctatcg tcattcatca agccgtttgt
     1681 cgtccccaac aaatgcttga gaaaatattc atgccctttt cctgagcttg agatcagatt
     1741 tgcccgccat acgaagagat ttcttggaaa attcacttca ttatcaggat cttcaatcgc
     1801 gaatttcagt tttttctctt ggagctgtga ggccacgtac gcaccaacgt cttcaggtgt
     1861 ttctgcccct gctttttcag cttctttata cagatcgatg ccattttgat tgaaagtcgg
     1921 gtaagacgga agccacccca gccgcgcggc cagcacattg taatcagcgt ggtgcttgta
     1981 gcgggatgac gcagcaatcg gtgatgccaa atcactgatc ggctggtcct cataacgcca
     2041 ctgatctgtc gcaaagtaga aaaatgaggt gccgttttgc agcttgggca cgccctccca
     2101 gtcctttgca gttgcaatcg tctgccaccc ttcagcaggt cggagctttt cctgccccac
     2161 gtaatgggcc cagcctcctc cgtttacgcc ttgggcgcct acaagtaaaa caagatttaa
     2221 caccgctcgg tagatcgtgt cggagttgaa ccagtggtta atgccggccc ctacgataat
     2281 catggatcgg ccgtctgtat cgatcgcatt ttgggcaaac tctctggcaa tcttaacgac
     2341 agcttctttt ttgattcctg tcatttgttc ctgccaggca ggcgtaaacg gctcaggatc
     2401 atcataggag acagccgatc gttcgccgat gccccggttc acgccgtagt tagccagtat
     2461 caagtcaaac acggtcgtga tgtacgtttc ttcaccgttc aggttcattt ttttaatagg
     2521 aagatcccgc tcgagcactt tgtttccgtc atttgaaaaa tacgggatgc gcaccgtgcc
     2581 gatttcgtcc tctattccca gcacagagag acggggttca atcggttccc cggtttcttc
     2641 atcaatcatg tgcaggttcc atttctgctg cccgtcccag cgcgatccca ttgtcccttg
     2701 gggtatggca aatgaacttg tctgttcatc ccaaaccgca ggcttccact gatcatgctt
     2761 tgtctgccgc ccgatgtcct tcgcatgcag aaaccgtccc gctgtgtata cgccattttc
     2821 ttttgacagg gtgacgagaa atggaaaatc agtgtattgc ttcgcgtact caataaaacg
     2881 ttcagtttct tggttcacgt aaaattcctg cagaatgaca tgacccatcg caatcgcaag
     2941 tgccccgtca gtcccttggc gaatactcag ccagtcatcc gcgaactttg aggattccgc
     3001 aaaatccgga ctgatcgaaa tgaccttagc gcctttatag cgggcctccg ccaaaaaatg
     3061 cgcgtcaggc gttctcgtta acggaacgtt ggagccccat gtgatgatat agccggaatt
     3121 gtaccaatca ctgctttccg gaacgtccgt ctggtcaccc caaatttgcg gggatgctgg
     3181 tggaagatcc gcataccagt cataaaaact gagcataggg cctccgatta acgacataaa
     3241 ccgggagcct gatgcatggc tgatcatgga catggccgga atcggagaaa aaccgacgtt
     3301 tcggtcaggc ccatatttca tcactgtata cagcagagag gctgaaatca gcttcagcac
     3361 ctccggccat tcagcgcgca caaaaccgcc tttccctctc gcctgtttat aggacttcgc
     3421 tttttcaggg ttttcgacga tcgatttcca ggcttccaat ggattttgat gttcttgcag
     3481 tgcctcccgc cataaattaa tcagtacacc gcgcacgtat ggatatttca cacgcagcgg
     3541 gctgtagata taccatgaaa aactggcccc ccgcgggcag cctctcggtt caaaatcagg
     3601 catatccggt cctgttgatg gataattcaa attttgccct tcccacgtga caattccgtt
     3661 ttttacataa atattccagc tgcaagaccc tgtacagtta acgccgtggg tggagcgaac
     3721 gactttgtcg tactgccatc tgtttctgta tacattctcc caatcgcgat cctcgcgggt
     3781 ggtttggcta tgtttatttg aatggtgttc gataggagag aaataattca atctcctaaa
     3841 caacggactc attttctttt tcttcatgag agttcactcc ttccgagtca ggtgatgcta
     3901 agttcactat aaacagagac agcgtgtttc cttgtgaact atgtcacaca ctctgctttt
     3961 ttcacaaaat gttcacacaa aggagaagga aggattttca caagatgtga ggaaggctga
     4021 gttcaggcag gacgcttggg tcattagctg cctttcattc aaagatcaaa aaaaccggct
     4081 ctatttaaga accgggctca gcgttttcat cctgtgatgt atgcagatac cgcaaaaata
     4141 attgatagga acaaaaaaca ttttgctgaa gcatagccaa aaagttcatt tgcagctgcg
     4201 gatgataaga catcattttc ttaaatatgt aatatgggat gttgagaatc agaatgtctg
     4261 aagtggcatt gactgagata aagggcgata aataaagccc gcctttttca tcaatcggaa
     4321 acacatcgcc tttttcccac agcgcaacgg ttttcgaccc ttcagggagc cttgtgtcca
     4381 tgaaacggac actgcctttt aatacaatat aaacagattg agaatgaaga aaagatggag
     4441 actgatcaca tgagccgcgg ataaacgtgc cgtttttcag caaggtttcg acaatggata
     4501 gaggcacttc attaaacata ggaagttgtt tcagaaataa taaatagtca cactgattca
     4561 taggaaaacc tcctgtgcta aggatagctt tagtgtagct cgatcgagcc tgtacagcag
     4621 tgatgtattt cacagcctgt atgatgaatg tcacttatca ggagggtgac tgcatttata
     4681 atgaaagaaa aaaggaggat ttcgatgaag gcgctgattc cgaagcagca cggcgcgtgg
     4741 gcgatgctgc tgatcccatt tttactcggc atggtcaagg gaggccccgt tatttggcat
     4801 attccgctct tcctaggctg gcttttccta tacttagcgg tttatcccgt tacgcttgcc
     4861 ttaaaaaaga aacaaagcaa acaatatcaa aagtggatgt gttattacgg ttttcccgcc
     4921 tgctgctttt tgatgatctc ggtctttcat aagccgcctc tcatctgggt gggcgtttct
     4981 ttactgccgc tgtttctcat acatatgtat tttgcccgcc gaaaaaacga acgagcccta
     5041 ttgaatgatg ttgcaggtgt cttgttcttt tgttcgggcg ggtttgcgag ctgctggctg
     5101 gggatgggaa cccttgacgg ctgggcttgg tttattttct tgcagtctgc tttatttttt
     5161 atcgggagtt ccttttatgt gaaatcggtg attcgtgaaa gaaaaaacag ggcatttgca
     5221 tactggtcat ggggatatca cctgctgctc ccctttttat ccgctctttt cggagcagga
     5281 tgggcgtttc tcgcttttat cccgagcagc ttgcgggcat ggttttttca tggaagggat
     5341 tggcccgtga aaacgattgg cattctggaa atcgtgaatg cctgcttctt tcttgccgtc
     5401 atgtgcctgt ttatcacaag gtaaaaaaac aaggacaccg ctgtccttgt ttttttcagt
     5461 caatattgca aatctccagc gggcaatttt cacactcaat ctcacatcgt aaatagtccc
     5521 gcttgtgcaa aataattttt ccggattcgt ctatcgaaat aacccctttt ttgcggagat
     5581 ctcccagcat acggttgatg ctttcccgtg cagccgcgca aaactttgcc aaatcctgat
     5641 ttgtcaggac aatgttaatc agaatgccgt cgcttcgctc cactccgtag ctgtttgata
     5701 aacggataag ggtggaatag agcgccccct ttttgccatg aagaagcaga tccctgattt
     5761 tggactgaat cttccggagg tgcgtgctca tccatttcat gaactcaaat gtcaaagcgc
     5821 cattttggat taattctttt tccagcttat ttttattaat gacgagcacc tcgccatcct
     5881 ctagcacttt tgcactgagc atataccttg gttcttcagt gaaaagtgtt aattctccga
     5941 cgatatcatg cttttggcag attctaagcg tcaggtcttt tccatcagat gtcagcttgc
     6001 cgatttcaat gagtcctgat tgaatcagat aaagctcttc tgcatccatt ccttctcgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat cgattccagc aattcatgca
     6121 gatcgctgga tataagatca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgt gtgtttattg taacgtgaat tgatttgtac ccatcgagaa
     6241 aaaactaaca atcttgtgaa tgcccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa tacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattggca
     6481 attcccgctt gcttcgaaaa atagaaaggc accagtttaa aaacagtccc gtttcctatg
     6541 cctgagcaga cggccacggt taatgatcca aacgtataaa ggccgattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcccgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc aaacaatacg tgcagtaagg caaagacagc cagcaaaatc
     6961 agatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc actccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagaat ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgccgtcacc
     7321 aaagaaatct cgcccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgatcgt gattacattt gttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagtttgtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgtgc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ctgcacttcg cattgcaaag
     8041 aagtaacgca cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccttgtcaat ttttccattt
     8461 tggtacagtg aagtttctga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tttccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acgattaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct caccgcggta gccatcctcc ggcatcggtt tttccaatcc gagtgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatac tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gccttccctt tatcaaaatg ggcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttaa tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt tcttttcaca
     9901 tttttttcaa attatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaacga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 tcgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt attcagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgccgc
    10621 tccacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagtt tggagctttt gaaggcttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcgga gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtaattgat gagtttaaag atttgattcc gattattcct tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcaa gcaccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 taggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtt ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatt caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 tgaggtgatc ggccatgaat aacataatcc ctatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gatgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat tgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtctcag cgccgctttg atgccggcca ccacgcttcc gctttgcgcg gttcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagggcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggtattcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgctgctcat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatatcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacaattt atttttacgg cgccgccgcg
    13921 tacctgaagg agcaaatcat tgacgctttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgctgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgagaatc
    14161 gaaaagaaat tcactgatcc tttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggagag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccggaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagaa agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatggggg tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacagctgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcacatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gattcccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaagcc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cctggcatgc cctccagccc tctcacaaaa aatgatgctg ggtgatgagg agcggatgga
    15721 agatacctgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgtcgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc gcctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat acgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaaacac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctgggttca ggccgttgcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgacg ctgtgcggct cgggctgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcatta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacttat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agcgctggcc
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctgcca ttcagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccgga
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaagc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta cgtataagtt attaatgaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtgc tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg agacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa attcccagcg
    17341 taaggagttg caattaaact gggaaattca aatgaatcta tgatactttc taccaactgc
    17401 ccagtattta catcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tgcgaactca
    17581 tctgttggat caaattcgat ctttctcggc cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat tcccatggag aacatacgtg
    17701 aatgctttat caaaagtaac gcctagatta gttggcacag cagaaaacgg gattgttttt
    17761 acaatagtgt ttaaatctgc atcaatgacc gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggcgatggc ggtaaaacaa gtatcccggc caccgtgagc
    17881 ggactgccgt agaaaggcgg cacgatgaga agatcttcca ctgtcatttg actgaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc agtatgaatc
    18001 acagaaacag ccccgtctcc ttgtccatat tgatttcgca caggcgacac actgacaaga
    18061 agcgtaatgg ccccttgtac tctcacggca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgcctgtact ccatgtaaca
    18181 gccgctgacg cttcggccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt cccggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcaccaca catagttgat
    18361 taaatcgcaa tagctcccgg tgaaacccca agagatatga cagtctccac ggagtaatca
    18421 tccgtgttgt aaacagtgat gctctgttct aggacatgag ttgcatacag aaactcgcca
    18481 ttcggggtaa acgcaaagtc tcttgccgac tgtggaacat ttcctataac gcctgctcca
    18541 tttggactga cagaatataa attgccagtg aagccgtcat gtaaatacac acctgttcca
    18601 ctcgtaaaca ttcgatattc cccttcatac tccagctctt gggtgctgct gatggtaaac
    18661 gtatttaaat caataaccgt caaataatta aaaaagaatt cttgttctaa tacataggca
    18721 taccgctccg gccaatttgt ttctatggtt gatacgataa gctctcgttc aattgttcct
    18781 gtgacttcac cggtagttag atccactttt tgcactatac caaaatttag aacataggcg
    18841 aataacccat tgggatcgat tgcaacatca tacccttcca caggaatcga cctatccaca
    18901 gttaacgtat caattccaat cacagaaacc gcagtaccgg tgaaaacata agcaaactca
    18961 tgattaggga taaatctaat caatcgaggc ggctgatcca gcaatataga tgctgtcact
    19021 gttaatgtgt cataatcgat gacagaaatc acattgttgt tgggatgtaa gacaaacaca
    19081 gcgcttttat ccggggtaat ttcaatacct gccggattgt acggaagagc aatcgttgtc
    19141 acaacagaat gagtgtttgt atcaatcaca gaaactgatt gatcatttgg attcgctgta
    19201 aacgcataaa cgggttccgg ctccggtaca agcacaatcg tccccgtcac cgataaagga
    19261 ctgccgtaaa acggcggaac aacaacaagg ttctcaatcg tgatgtcact gatatccggg
    19321 caatcatccg gttcatcgga ataatagacg acttgatcga tctctgcatt gtgaatgacg
    19381 gaaacagccc cgtccccttg tccatattga tttcggacag gtgagacact gacgagtagc
    19441 gtaacggttc cctgcaggcg cactgcaaat tgaacaccga cctcatcagg ctcaggcccc
    19501 gtttgaatta agcaacggtc actgacacaa gaaaggctgt ctgcattcca cgtcacgttt
    19561 gcaacagctt cagccggatc aacgacaaac ccttcaggta attcaatcgg tgcttgaaac
    19621 atggcttctc ggcttgcttc tccctcacaa aaacataagc actcttcttg ttcttgttct
    19681 gctcctgctt tttctttaaa ggaaagcttg ttttttctca ttccttcact tccttttcag
    19741 acatacactg ctcacgcaga tataacagaa tatggaaggg taacgtgttt gcttgtacaa
    19801 attgctgagg gtaaaagctt ctttttgaaa atatatctcc aaacatgcgg tgtaacgaaa
    19861 gaaaaaattg cggttttttt gcgcttctca caagaatgtt gatgataaaa tatgacatat
    19921 atagaattat gaagggaggg atttgcaaac gtgacaggtg tcatatcttc ttcttccatc
    19981 ggagaaaaga ttaacgaatg gtatatgtac atacgccgat tcagcatacc cgatgcagaa
    20041 tatttgcgac gagaaatcaa gcaagagctg gatcaaatgg aagaagatca agaccttcat
    20101 ttgtactatt cactgatgga gtttcggcac aacctgatgc ttgagtacct tgaaccgtta
    20161 gaaaaaatga ggattgagga acagccgaga ctgtctgatc tgctgcttga gattgataaa
    20221 aaacaggctc gtttaactgg tctgcttgag tactatttta atttcttcag aggcatgtat
    20281 gagctggatc gccgtgaata tgtattagcc attcaattct ttaaaaaagc tgagagcaag
    20341 ctggtttttg tgaaagataa aatcgataaa gctgaattct ttttcaaaat gtcagaagtc
    20401 tattattata tgaaacaaac ttatgtctcc atggactatg cacgtcaagc attcgaaata
    20461 tacagtgaac agaccacata tgatatcaga atgattcaat gccagtcctt attcggagcc
    20521 aactttttgg atttaaaaca atacgaaaaa gcaattgccc attttcaaaa agcctttaca
    20581 cttgcaaaaa cagagcagca gccccaatta atgggcagaa cactttataa catagcactc
    20641 tgcaagcaaa accaaaacag ttttgaatca gcgatagagt atgtaaaaaa atctattcaa
    20701 gtatttgaag gatctaaaat gctcccttca ctgccacaag cttttttcct aattacacaa
    20761 atttatttta aattaggtaa gattgataac gcctgtgaat atcataaaaa aggaaaagag
    20821 tattctgcag ttgcgggaga taccgtgtat ctaacggagt ttgaattttt ggaatcttta
    20881 tacttgtctg gaccggatga ggaacggata gaaaaatgtt ttgtttttct tgaaagtaaa
    20941 atgatgtatg cagatattga ggacttcgca cttgatgttg ctaaatatta tcatcaacag
    21001 gaaaattaca aaaaggcatc tcattacttt ttaaaggttg aagaagcaag acagcacatt
    21061 caaggggggg tgaatttata tgaaatggaa gtataaatta ttactcgctt gtttagctgt
    21121 gagtgctgta tttatcacag tcgaagtatc aaattcatca acagaacatt ttgatgttgc
    21181 gcaacgcgcc atgatctaaa ccgccgtcca tcggcggttt tttttgtccc ctctttaccc
    21241 aatctcccaa ttcatgctat gatttttttc aataatcttg aagagagtgg aaatgcagca
    21301 tgtctctgta aagtgtgaga acccacttta cacagtggaa tcgagaaaat gatgtgacgg
    21361 agttcgaaac gtcgagtgcg acagttgaac aggcagctga gacgatcggc gtaaacccgg
    21421 ctagaatcgc caagtccctg tccttcagag gggaaggata tcaggcgatt ctgattgtgg
    21481 cagccggcga tgccaagatc gacaacaaaa cgttcaggca aacatttggc tttaaagcaa
    21541 gaatgctctc tcctaatgag gtactggagc agacaggcca tgaaattgga ggagtttgcc
    21601 cctttggttt gg
//
