LOCUS       NZ_VIOH01000015        13270 bp    DNA     linear   CON 03-JUL-2024
DEFINITION  Bacillus subtilis strain FH1 NODE_17_length_13160_cov_119.023636,
            whole genome shotgun sequence.
ACCESSION   NZ_VIOH01000015
VERSION     NZ_VIOH01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 13270)
  AUTHORS   Khan,M.A., Khan,M.N., Imran,M., Hameed,A. and Hasan,F.
  TITLE     Draft genome of Bacillus subtilis FH1 isolated from tannery waste
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 13270)
  AUTHORS   Khan,M.A., Khan,M.N., Imran,M., Hameed,A. and Hasan,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2019) Department of Microbiology, Quaid-I-Azam
            University, Facutly of Biological Sciences, Islamabad, Federal
            45320, Pakistan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012028945.1-RS_2024_07_03
            Annotation Date                   :: 07/03/2024 03:57:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,286
            CDSs (total)                      :: 4,159
            Genes (coding)                    :: 4,053
            CDSs (with protein)               :: 4,053
            Genes (RNA)                       :: 127
            rRNAs                             :: 10, 16, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 7, 16, 11 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 62 of 106
            Pseudo Genes (incomplete)         :: 50 of 106
            Pseudo Genes (internal stop)      :: 18 of 106
            Pseudo Genes (multiple problems)  :: 21 of 106
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:36:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 13270
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VIOH01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13270
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     gene            complement(<1..1664)
                     /locus_tag="FLN47_RS17630"
                     /old_locus_tag="FLN47_17815"
     CDS             complement(<1..1664)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (2-30). E-value: 1.2e-16.
                     Score: 51.6. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17630_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-305). E-value:
                     2.8e-119. Score: 389.6. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17630_Condensation_DCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389714.1"
                     /locus_tag="FLN47_RS17630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_17815"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_167568938.1"
                     /sec_met_domain="Condensation (E-value: 2.1e-94, bitscore:
                     303.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-22, bitscore:
                     65.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTINGQL
                     DLERFQKSMDAVFDRYDIFRTAFIYKNVAKPRQVVLKQRHCHVHVEDISHLNEKDKEHC
                     TEAFKEQDKSKGFDLQTDVLMRISILKWAPDHYVCIWSHHHILMDGWCLGIVIKDFLHI
                     YQALGKGQFPDLPPVQPYGTYIKWLMQQEREEAAEYWKKRLQHFEKASPLPKRTDQMSD
                     GTLQQITFTIPEKETSELQKIAAACGATLNTVFQALWGIMLQKFNRRDDAVFGSVISGR
                     PSELKDVENMVGLFINTIPIRVQSDFLSFSDLVSGMQKDMTEAEAYSYFPLYDIQAQSA
                     LKQELIDHIIVFENTPTQQEIEELNQAGSFDFSVKDFEMEEVTNYRCSVKVIPGRTLYV
                     RIHFHTGTYQPNMMSEIKDYLQHMISDVISDPSLPVSKMTLLDEDKTRKIVSQNNRTVS
                     VSPEAPTLHGLFERQAAVTPERPAIRFSGGSLTYTELDMYANRLAAHLAARGVTNESIV
                     GILSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLS"
     source          1..13270
                     /altitude="0.3 m"
                     /collected_by="Dr. Abdul Hameed"
                     /collection_date="1992-11-20"
                     /db_xref="taxon:1423"
                     /geo_loc_name="Pakistan: Lahore"
                     /isolation_source="tannery waste"
                     /mol_type="genomic DNA"
                     /organism="Bacillus subtilis"
                     /strain="FH1"
                     /submitter_seqid="NODE_17_length_13160_cov_119.023636"
     cand_cluster    1..13270
                     /SMILES="NC(CCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13270
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:>13268](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..>13268)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS_motif       complement(30..71)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0007"
                     /evalue="3.10E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="545"
                     /protein_start="531"
                     /score="20.2"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       complement(597..713)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0006"
                     /evalue="5.90E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="356"
                     /protein_start="317"
                     /score="60.5"
                     /tool="antismash"
                     /translation="QKDMTEAEAYSYFPLYDIQAQSALKQELIDHIIVFENTP"
     aSDomain        complement(750..1643)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17630_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.80E-119"
                     /label="FLN47_RS17630_Condensation_DCL.1"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="305"
                     /protein_start="7"
                     /score="389.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="QDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTINGQLDLERFQK
                     SMDAVFDRYDIFRTAFIYKNVAKPRQVVLKQRHCHVHVEDISHLNEKDKEHCTEAFKEQ
                     DKSKGFDLQTDVLMRISILKWAPDHYVCIWSHHHILMDGWCLGIVIKDFLHIYQALGKG
                     QFPDLPPVQPYGTYIKWLMQQEREEAAEYWKKRLQHFEKASPLPKRTDQMSDGTLQQIT
                     FTIPEKETSELQKIAAACGATLNTVFQALWGIMLQKFNRRDDAVFGSVISGRPSELKDV
                     ENMVGLFINTIPIRVQS"
     CDS_motif       complement(759..854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0005"
                     /evalue="4.70E-20"
                     /label="C5_DCL_263-294"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="302"
                     /protein_start="270"
                     /score="64.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSELKDVENMVGLFINTIPIR"
     CDS_motif       complement(1089..1127)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0004"
                     /evalue="8.10E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="192"
                     /protein_start="179"
                     /score="9.1"
                     /tool="antismash"
                     /translation="PYGTYIKWLMQQE"
     CDS_motif       complement(1173..1238)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0003"
                     /evalue="3.30E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="164"
                     /protein_start="142"
                     /score="35.6"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVIKDFLHIY"
     CDS_motif       complement(1455..1571)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0002"
                     /evalue="9.00E-18"
                     /label="C2_DCL_024-062"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="70"
                     /protein_start="31"
                     /score="56.6"
                     /tool="antismash"
                     /translation="AYFEQASFTINGQLDLERFQKSMDAVFDRYDIFRTAFIY"
     aSDomain        complement(1575..1658)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17630_NRPS-COM_Nterm.1"
                     /evalue="1.20E-16"
                     /label="FLN47_RS17630_NRPS-COM_Nterm.1"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="30"
                     /protein_start="2"
                     /score="51.6"
                     /tool="antismash"
                     /translation="QQPEIQDIYPLSFMQEGMLFHSLYDEQS"
     CDS_motif       complement(1593..1634)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17630_0001"
                     /evalue="2.90E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="FLN47_RS17630"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.9"
                     /tool="antismash"
                     /translation="YPLSFMQEGMLFHS"
     gene            complement(1681..9363)
                     /gene="ppsB"
                     /locus_tag="FLN47_RS17635"
                     /old_locus_tag="FLN47_17820"
     CDS             complement(1681..9363)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-29). E-value: 1.6e-15.
                     Score: 48.0. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-309). E-value:
                     1.5e-111. Score: 364.2. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-865). E-value:
                     2.4e-110. Score: 360.9. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (970-1036). E-value: 1.8e-23. Score:
                     74.5. Matches aSDomain: nrpspksdomains_FLN47_RS17635_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1341). E-value:
                     2e-103. Score: 337.5. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1505-1903). E-value:
                     1.7e-118. Score: 387.7. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2011-2078). E-value: 1.8e-20.
                     Score: 64.9. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (2088-2392). E-value:
                     6.8e-158. Score: 518.7. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2403-2553). E-value: 6.5e-54.
                     Score: 173.9. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17635_TIGR01720.1"
                     /codon_start=1
                     /gene="ppsB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389715.1"
                     /locus_tag="FLN47_RS17635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_17820"
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsB"
                     /protein_id="WP_167568940.1"
                     /sec_met_domain="Condensation (E-value: 5.1e-96, bitscore:
                     308.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-126, bitscore:
                     409.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-17, bitscore:
                     51.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQSAQIQDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNL
                     CVDSFQKSLNLLVSRYDIFRTIFIKEVPDLTGPQQVVLSNRELTVYREDISRLADQEQQ
                     TLIDAFMTKDREKGFDLQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILKEFF
                     SMYDSLKNNSPVQLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRT
                     ADGNYKADQVSFSLASDMVEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSV
                     ISGRPSAIDGIESMVGLFINTVPVRIRSAEGITFSSLVKAVQEDILSSEQHGYYPLYEI
                     QNHSPLKQGLIDHIFVFENYPVQLHQALSVESENDEGALKLSDISMSEQTNYDFNIVIV
                     PGESFYIKFSYNADVYEREEMLRIQGHLKQALDCILTNPDVAVSDINIVPPEEQQVIQS
                     FNETERPYVNKTIPQLFEEQAHKTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVG
                     SGDIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAERLSFLLKDSQAAQLLIEEDL
                     ISLIPPSYEGNTITIEHTESYQTEAPNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANT
                     LQWRREEYGMAEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKI
                     ARYKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLELSQIICPSAELAN
                     EYGPTENSVATTILRHLNEKERITIGHPIRNTKVFVLHGNQMQPIGAAGELCISGAGLA
                     RGYYKQPELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIRGYRIEL
                     REIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVPEKGNSLPDLYQHLAGTLPSYMIP
                     ASIINIGRMPLTSSGKLDRFALPEPENNTSVTYMAPRTLIEADLAHIWEDVLNKQQIGI
                     RDDFFQLGGQSLKAAALVSRIHKKLNVELPLSEVFSYPTVESMAVKLMSLKEHAFTQIE
                     PADQRDVYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLNRQRLRSVLTELVNRHE
                     ALRTVFVLDRDEPVQIIYPEIAFDLKELEMESEQMLESAIETFIKPFDLSSGPLFRACV
                     ITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCGKELPALNLHYKDFAVWQQEKHP
                     KELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFSGGTIELNIDKDTADELHRLMAE
                     TGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTLAMRSKPEG
                     HKTFSSYLQDIRHLALTAYEHQDYPFEELADKLFTNREVNRNPLFDAMLVLQSSEDFRF
                     EVPGLSISSVTPKHDISKFDLTLHAEEHPSGIRCRFEYSTALFEEETITQWASYFIELV
                     KGVTADTEMRISDMQLLPAAERRLLLEKMGQYAAYPRNENIVSLFEKQAAKYPEHIAVV
                     CGHSQLTYRDLNEKAERAAAMLIKQGVRTGDIVGLMLDRSPDMIIGVLSILKAGGAYLP
                     IDPEYPKERISFMLNDSGAKLLLTERGQNKPADYTGHILYIDECENDSFPADVNIQEIV
                     TDQPAYVIYTSGTTGQPKGVIVEHRNVISLLKHQNLPFEFNHEDIWTLFHSYCFDFSVW
                     EMFGALLNGGTLVVVSKETARDPHAFRLLLKKERVTVLNQTPTAFYGLMLEDQNHTDHL
                     NIRYVIFGGEALQPGMLQSWNKKYPHTDLINMYGITETTVHVTFKKLSAADIVKNKSNI
                     GRPLSTLQAYVMDAHMNLQPIGVPGELYIGGEGVARGYLNRDELTADRFVSNPYLPGDR
                     LYRTGDLAKRLSNGELEYLGRIDEQVKVRGHRIELGEIQAALLQYPMIKEAAVITRADE
                     QGQTAIYAYMVIKDQQAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKLDQKAL
                     PEPEKHAYTADDISPRNEIETVMAEIWEELLNVDELGVSANFFELGGDSIKALQVCARL
                     KQRGFETTVREMFEHQTLGELSARVRKDVRAIDQGPVEGEITWTPIQQWFFSQSLESHH
                     FNQSVMIYRAERFDEAALRKVLKSLVTHHDALRIVCRHEDGRQVQINRGIDLSDEELYA
                     LELFDVKDSLTEARYTIEEAASRMQEHIRLETGPLLHAGLFRTENGDHLFLTIHHLVVD
                     AVSWRILFEDFSAAYKQAVSGESIKLPQKTDSYLTYSQRIVDYSKSRQVQREAAYWDEC
                     ESRHIQPIPKDNDAASNTFKDTEVIDFELSRHHTELLLTAAHKAYSTEMNDILLTALGL
                     ALQKWTGNNQFKISMEGHGRESYLEDIDISRTVGWFTSIYPVWLDMRDSDHKDKEERLG
                     HLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNYLGQFDQDIQSNAFEVS
                     DIKPGNEISPNWERPYALDISGAVSSGCLNMHIIYNRVQFEEKTIQTFSRHFKQTLENI
                     IEHCTGKENREWSASDFTDEDLTLDELSEIMGAVNKL"
     aSDomain        complement(1705..2154)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_TIGR01720.1"
                     /evalue="6.50E-54"
                     /label="FLN47_RS17635_TIGR01720.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2553"
                     /protein_start="2403"
                     /score="173.9"
                     /tool="antismash"
                     /translation="LGHLIKQTKDMLHRIPHKGAGYGVLKYISKRWGSQKNSPEISFNY
                     LGQFDQDIQSNAFEVSDIKPGNEISPNWERPYALDISGAVSSGCLNMHIIYNRVQFEEK
                     TIQTFSRHFKQTLENIIEHCTGKENREWSASDFTDEDLTLDELSEI"
     aSModule        complement(1705..6201)
                     /complete
                     /domains="nrpspksdomains_FLN47_RS17635_Condensation_LCL.1"
                     /domains="nrpspksdomains_FLN47_RS17635_AMP-binding.2"
                     /domains="nrpspksdomains_FLN47_RS17635_PCP.2"
                     /domains="nrpspksdomains_FLN47_RS17635_Epimerization.1"
                     /domains="nrpspksdomains_FLN47_RS17635_TIGR01720.1"
                     /locus_tags="FLN47_RS17635"
                     /monomer_pairings="Thr -> D-Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2074..2133)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0025"
                     /evalue="4.90E-08"
                     /label="NRPS-E6"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2430"
                     /protein_start="2410"
                     /score="25.3"
                     /tool="antismash"
                     /translation="TKDMLHRIPHKGAGYGVLKY"
     aSDomain        complement(2188..3099)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_Epimerization.1"
                     /evalue="6.80E-158"
                     /label="FLN47_RS17635_Epimerization.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2392"
                     /protein_start="2088"
                     /score="518.7"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDA"
                     /tool="antismash"
                     /translation="EGEITWTPIQQWFFSQSLESHHFNQSVMIYRAERFDEAALRKVLK
                     SLVTHHDALRIVCRHEDGRQVQINRGIDLSDEELYALELFDVKDSLTEARYTIEEAASR
                     MQEHIRLETGPLLHAGLFRTENGDHLFLTIHHLVVDAVSWRILFEDFSAAYKQAVSGES
                     IKLPQKTDSYLTYSQRIVDYSKSRQVQREAAYWDECESRHIQPIPKDNDAASNTFKDTE
                     VIDFELSRHHTELLLTAAHKAYSTEMNDILLTALGLALQKWTGNNQFKISMEGHGRESY
                     LEDIDISRTVGWFTSIYPVWLDM"
     CDS_motif       complement(2194..2244)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0024"
                     /evalue="5.10E-09"
                     /label="NRPS-E5"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2390"
                     /protein_start="2373"
                     /score="28.0"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPVWL"
     CDS_motif       complement(2647..2712)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0023"
                     /evalue="1.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2239"
                     /protein_start="2217"
                     /score="36.3"
                     /tool="antismash"
                     /translation="LFLTIHHLVVDAVSWRILFEDF"
     CDS_motif       complement(2935..3000)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0022"
                     /evalue="1.60E-03"
                     /label="C2_LCL_024-062"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2143"
                     /protein_start="2121"
                     /score="10.9"
                     /tool="antismash"
                     /translation="RFDEAALRKVLKSLVTHHDALR"
     CDS_motif       complement(3058..3084)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0021"
                     /evalue="2.90E-03"
                     /label="NRPS-E1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2102"
                     /protein_start="2093"
                     /score="10.8"
                     /tool="antismash"
                     /translation="WTPIQQWFF"
     aSDomain        complement(3130..3330)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_PCP.2"
                     /evalue="1.80E-20"
                     /label="FLN47_RS17635_PCP.2"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="2078"
                     /protein_start="2011"
                     /score="64.9"
                     /tool="antismash"
                     /translation="ETVMAEIWEELLNVDELGVSANFFELGGDSIKALQVCARLKQRGF
                     ETTVREMFEHQTLGELSARVRK"
     CDS_motif       complement(3625..3690)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0020"
                     /evalue="3.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1913"
                     /protein_start="1891"
                     /score="35.3"
                     /tool="antismash"
                     /translation="YLGRIDEQVKVRGHRIELGEIQ"
     aSDomain        complement(3655..4848)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_AMP-binding.2"
                     /evalue="1.70E-118"
                     /label="FLN47_RS17635_AMP-binding.2"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1903"
                     /protein_start="1505"
                     /score="387.7"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEKQAAKYPEHIAVVCGHSQLTYRDLNEKAERAAAMLIKQGVRTG
                     DIVGLMLDRSPDMIIGVLSILKAGGAYLPIDPEYPKERISFMLNDSGAKLLLTERGQNK
                     PADYTGHILYIDECENDSFPADVNIQEIVTDQPAYVIYTSGTTGQPKGVIVEHRNVISL
                     LKHQNLPFEFNHEDIWTLFHSYCFDFSVWEMFGALLNGGTLVVVSKETARDPHAFRLLL
                     KKERVTVLNQTPTAFYGLMLEDQNHTDHLNIRYVIFGGEALQPGMLQSWNKKYPHTDLI
                     NMYGITETTVHVTFKKLSAADIVKNKSNIGRPLSTLQAYVMDAHMNLQPIGVPGELYIG
                     GEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVR"
     CDS_motif       complement(3772..3861)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0019"
                     /evalue="3.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1864"
                     /protein_start="1834"
                     /score="57.8"
                     /tool="antismash"
                     /translation="PIGVPGELYIGGEGVARGYLNRDELTADRF"
     CDS_motif       complement(3976..3999)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0018"
                     /evalue="2.50E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1796"
                     /protein_start="1788"
                     /score="2.0"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       complement(4378..4437)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0017"
                     /evalue="4.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1662"
                     /protein_start="1642"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGQPKGVIVEH"
     CDS_motif       complement(4621..4662)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0016"
                     /evalue="1.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1581"
                     /protein_start="1567"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LSILKAGGAYLPID"
     CDS_motif       complement(5182..5295)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0015"
                     /evalue="3.90E-13"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1394"
                     /protein_start="1356"
                     /score="41.7"
                     /tool="antismash"
                     /translation="LALTAYEHQDYPFEELADKLFTNREVNRNPLFDAMLVL"
     aSDomain        complement(5341..6201)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.00E-103"
                     /label="FLN47_RS17635_Condensation_LCL.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1341"
                     /protein_start="1054"
                     /score="337.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIADG"
                     /tool="antismash"
                     /translation="VYPLSFSQKRLYALHQLADDSTGYNMPAVLELRGNLNRQRLRSVL
                     TELVNRHEALRTVFVLDRDEPVQIIYPEIAFDLKELEMESEQMLESAIETFIKPFDLSS
                     GPLFRACVITMGNNRGFLLLDMHHIIADGVSMSTLVQEFTDLYCGKELPALNLHYKDFA
                     VWQQEKHPKELYKKQEAYWLGQLGGSLPTLELPLDKTRPRLPDFSGGTIELNIDKDTAD
                     ELHRLMAETGTTLYMILLAVYSILLSKLSGQEDIVVGSPAAGRPHADLERVIGMFVNTL
                     AMRSKP"
     CDS_motif       complement(5350..5439)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0014"
                     /evalue="8.90E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1338"
                     /protein_start="1308"
                     /score="53.4"
                     /tool="antismash"
                     /translation="DIVVGSPAAGRPHADLERVIGMFVNTLAMR"
     CDS_motif       complement(5698..5730)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0013"
                     /evalue="3.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1222"
                     /protein_start="1211"
                     /score="13.2"
                     /tool="antismash"
                     /translation="HYKDFAVWQQE"
     CDS_motif       complement(5761..5826)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0012"
                     /evalue="1.90E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1201"
                     /protein_start="1179"
                     /score="30.0"
                     /tool="antismash"
                     /translation="MHHIIADGVSMSTLVQEFTDLY"
     CDS_motif       complement(6022..6132)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0011"
                     /evalue="7.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1114"
                     /protein_start="1077"
                     /score="53.7"
                     /tool="antismash"
                     /translation="YNMPAVLELRGNLNRQRLRSVLTELVNRHEALRTVFV"
     aSDomain        complement(6256..6453)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_PCP.1"
                     /evalue="1.80E-23"
                     /label="FLN47_RS17635_PCP.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="1036"
                     /protein_start="970"
                     /score="74.5"
                     /tool="antismash"
                     /translation="EADLAHIWEDVLNKQQIGIRDDFFQLGGQSLKAAALVSRIHKKLN
                     VELPLSEVFSYPTVESMAVKL"
     aSModule        complement(6256..9342)
                     /complete
                     /domains="nrpspksdomains_FLN47_RS17635_Condensation_DCL.1"
                     /domains="nrpspksdomains_FLN47_RS17635_AMP-binding.1"
                     /domains="nrpspksdomains_FLN47_RS17635_PCP.1"
                     /locus_tags="FLN47_RS17635"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(6739..6804)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0010"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="875"
                     /protein_start="853"
                     /score="34.8"
                     /tool="antismash"
                     /translation="YIGRFDDQVKIRGYRIELREIE"
     aSDomain        complement(6769..7941)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_AMP-binding.1"
                     /evalue="2.40E-110"
                     /label="FLN47_RS17635_AMP-binding.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="865"
                     /protein_start="474"
                     /score="360.9"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEEQAHKTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSG
                     DIVAVMMGRSMEMPAALLGIWKAGGAYMPLDPHFPAERLSFLLKDSQAAQLLIEEDLIS
                     LIPPSYEGNTITIEHTESYQTEAPNMPPGDLAYLIYTSGTTGRPKGVLVDHHGIANTLQ
                     WRREEYGMAEQDISLHLFSYVFDGCVTSLFTPLLSGACVLLTTDDEAKDVLALKRKIAR
                     YKVSHMIIVPSLYRVLLEVMTADDAKSLRIVTFAGEAVTPDLLELSQIICPSAELANEY
                     GPTENSVATTILRHLNEKERITIGHPIRNTKVFVLHGNQMQPIGAAGELCISGAGLARG
                     YYKQPELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFDDQVKIR"
     CDS_motif       complement(6886..6975)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0009"
                     /evalue="3.20E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="826"
                     /protein_start="796"
                     /score="48.2"
                     /tool="antismash"
                     /translation="PIGAAGELCISGAGLARGYYKQPELTQKAF"
     CDS_motif       complement(7072..7104)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0008"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="764"
                     /protein_start="753"
                     /score="5.7"
                     /tool="antismash"
                     /translation="EYGPTENSVAT"
     CDS_motif       complement(7477..7536)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0007"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="629"
                     /protein_start="609"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AYLIYTSGTTGRPKGVLVDH"
     CDS_motif       complement(7714..7755)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0006"
                     /evalue="6.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="550"
                     /protein_start="536"
                     /score="16.1"
                     /tool="antismash"
                     /translation="LGIWKAGGAYMPLD"
     CDS_motif       complement(8281..8397)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0005"
                     /evalue="3.10E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="361"
                     /protein_start="322"
                     /score="61.4"
                     /tool="antismash"
                     /translation="QEDILSSEQHGYYPLYEIQNHSPLKQGLIDHIFVFENYP"
     aSDomain        complement(8437..9342)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.50E-111"
                     /label="FLN47_RS17635_Condensation_DCL.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="309"
                     /protein_start="7"
                     /score="364.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="QDIYPLSHMQEGMLFHSLMDFSSKAYIEQTSFTITGNLCVDSFQK
                     SLNLLVSRYDIFRTIFIKEVPDLTGPQQVVLSNRELTVYREDISRLADQEQQTLIDAFM
                     TKDREKGFDLQKDPLMRLALFDRGDSQYTCVWTHHHIIMDGWCLGIILKEFFSMYDSLK
                     NNSPVQLGSTVPYSRYIEWLGEQDQEETAAYWSEYLKEYGNTASIPRIKRRTADGNYKA
                     DQVSFSLASDMVEKLTEAAQNWGVTLNTLFMSIWGVLLHRYNAADDAVFGSVISGRPSA
                     IDGIESMVGLFINTVPVRIRS"
     CDS_motif       complement(8446..8541)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0004"
                     /evalue="2.40E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="306"
                     /protein_start="274"
                     /score="61.7"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSAIDGIESMVGLFINTVPVR"
     CDS_motif       complement(8866..8931)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0003"
                     /evalue="2.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="166"
                     /protein_start="144"
                     /score="35.9"
                     /tool="antismash"
                     /translation="HHHIIMDGWCLGIILKEFFSMY"
     CDS_motif       complement(9157..9270)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0002"
                     /evalue="2.10E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="69"
                     /protein_start="31"
                     /score="45.7"
                     /tool="antismash"
                     /translation="AYIEQTSFTITGNLCVDSFQKSLNLLVSRYDIFRTIFI"
     aSDomain        complement(9277..9363)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17635_NRPS-COM_Nterm.1"
                     /evalue="1.60E-15"
                     /label="FLN47_RS17635_NRPS-COM_Nterm.1"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="29"
                     /protein_start="0"
                     /score="48.0"
                     /tool="antismash"
                     /translation="MAQSAQIQDIYPLSHMQEGMLFHSLMDFS"
     CDS_motif       complement(9292..9333)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17635_0001"
                     /evalue="9.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="FLN47_RS17635"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS             complement(9388..>13268)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (235-640). E-value: 3e-96.
                     Score: 314.4. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17640_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (745-809). E-value: 1.1e-21. Score:
                     68.8. Matches aSDomain: nrpspksdomains_FLN47_RS17640_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (821-1132). E-value:
                     1.4e-148. Score: 487.9. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17640_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1140-1285). E-value: 1.3e-46.
                     Score: 150.2. Matches aSDomain:
                     nrpspksdomains_FLN47_RS17640_TIGR01720.1"
                     /codon_start=2
                     /gene="ppsA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="FLN47_RS17640"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_17825"
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsA"
                     /pseudo=""
                     /sec_met_domain="AMP-binding (E-value: 1.6e-106, bitscore:
                     344.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-15, bitscore:
                     45.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5e-89, bitscore:
                     285.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIA
                     GRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKL
                     ELTRDMSRNPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEINGSIC
                     CEMEFSTEVFLKATIERWADHFIEFLHAALSTPETSLAQINILSDKEKQKIVFGFNKTQ
                     VEFAQKDVPFHHIFEAKAEEIPEHIAVIDNETEISYRLLNERANRLARTLQNRKGPKPT
                     VAVLAKRSIDAIVGVLAVMKAGGVYIPIDSHYPKARIEYILRDSGADILLLQRELKHLI
                     SNSPESEMSHIFLDDEGSYEESNCNLNLSPALEEPVYIIYTSGTTGAPKGVIVTYRNFT
                     HAALAWRQIYELDRKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIY
                     KIMNSQRITVMESTPALIIPVMEYVYRNQFKLPDLDILILGSDMVKAQDFKTLTDRFGQ
                     SMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPIGVA
                     GELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGSIRLLGRMDY
                     QVKINGYRIETEEIESVLLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAAL
                     TKELPAYMIPAHLIPLENMPLTLNGKLDRNALPAPNNVLSRPYTAPVNDIQKTMAYIWE
                     DVLSMPRVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPL
                     ASQADQGPAEGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITE
                     HHDAIRMIFQHDQNGHVIQFNRGINHKDHELFGLYISDWTKASLERAHLDEKLAAEETV
                     IQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAAYQQALEKKE
                     IQLPPKTDSYLSYADGLTQIAESKQLLSEKPYWQTILDAHTAFLPKDIENVPDRLQMNS
                     DAAAFVLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQIVISTEGHGREG
                     HVPNIDISRTVGWFTSIYPILLDMGIPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLT
                     HIGELRHKEPEVSFNYLGQFSEEKEAETFQLSYYKPRHEIAGKREREYELDINALITDG
                     RLQVKAVYTQVFSKHSIEYFMDRFHRHLIETIEHCSQKKAREKTLSDFSNKELTLSALS
                     SIEDLVKDL"
     gene            complement(9388..>13270)
                     /gene="ppsA"
                     /locus_tag="FLN47_RS17640"
                     /old_locus_tag="FLN47_17825"
                     /pseudo=""
     aSDomain        complement(9412..9846)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17640_TIGR01720.1"
                     /evalue="1.30E-46"
                     /label="FLN47_RS17640_TIGR01720.1"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="1285"
                     /protein_start="1140"
                     /score="150.2"
                     /tool="antismash"
                     /translation="LAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQ
                     FSEEKEAETFQLSYYKPRHEIAGKREREYELDINALITDGRLQVKAVYTQVFSKHSIEY
                     FMDRFHRHLIETIEHCSQKKAREKTLSDFSNKELTLSALSS"
     aSModule        complement(9412..12561)
                     /complete
                     /domains="nrpspksdomains_FLN47_RS17640_AMP-binding.1"
                     /domains="nrpspksdomains_FLN47_RS17640_PCP.1"
                     /domains="nrpspksdomains_FLN47_RS17640_Epimerization.1"
                     /domains="nrpspksdomains_FLN47_RS17640_TIGR01720.1"
                     /locus_tags="FLN47_RS17640"
                     /monomer_pairings="Orn -> D-Orn"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(9766..9825)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0014"
                     /evalue="9.60E-09"
                     /label="NRPS-E6"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="1167"
                     /protein_start="1147"
                     /score="27.5"
                     /tool="antismash"
                     /translation="TKDMLRRVPNKGTGYGLLTH"
     aSDomain        complement(9871..10803)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17640_Epimerization.1"
                     /evalue="1.40E-148"
                     /label="FLN47_RS17640_Epimerization.1"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="1132"
                     /protein_start="821"
                     /score="487.9"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="EGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHLAL
                     RKITEHHDAIRMIFQHDQNGHVIQFNRGINHKDHELFGLYISDWTKASLERAHLDEKLA
                     AEETVIQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAAYQQA
                     LEKKEIQLPPKTDSYLSYADGLTQIAESKQLLSEKPYWQTILDAHTAFLPKDIENVPDR
                     LQMNSDAAAFVLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQIVISTEG
                     HGREGHVPNIDISRTVGWFTSIYPILLDMG"
     CDS_motif       complement(9880..9930)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0013"
                     /evalue="4.60E-09"
                     /label="NRPS-E5"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="1129"
                     /protein_start="1112"
                     /score="28.2"
                     /tool="antismash"
                     /translation="DISRTVGWFTSIYPILL"
     CDS_motif       complement(9994..10035)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0012"
                     /evalue="2.50E+00"
                     /label="Cy4"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="1091"
                     /protein_start="1077"
                     /score="1.6"
                     /tool="antismash"
                     /translation="LLLTALGMALSEWT"
     CDS_motif       complement(10336..10401)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0011"
                     /evalue="2.60E-11"
                     /label="NRPS-E2"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="977"
                     /protein_start="955"
                     /score="35.6"
                     /tool="antismash"
                     /translation="LLIALHHLVIDGVSWRILLEDL"
     CDS_motif       complement(10627..10698)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0010"
                     /evalue="2.20E-02"
                     /label="C2_LCL_024-062"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="880"
                     /protein_start="856"
                     /score="7.2"
                     /tool="antismash"
                     /translation="FNANALHLALRKITEHHDAIRMIF"
     CDS_motif       complement(10762..10788)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0009"
                     /evalue="4.60E-03"
                     /label="NRPS-E1"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="835"
                     /protein_start="826"
                     /score="10.2"
                     /tool="antismash"
                     /translation="LTPIQRRFF"
     aSDomain        complement(10840..11031)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17640_PCP.1"
                     /evalue="1.10E-21"
                     /label="FLN47_RS17640_PCP.1"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="809"
                     /protein_start="745"
                     /score="68.8"
                     /tool="antismash"
                     /translation="KTMAYIWEDVLSMPRVGIHDSFFELGGDSIKALQVAARLAAEGWS
                     MTIRDLFRYSTIQELCGHI"
     CDS_motif       complement(11089..11220)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0008"
                     /evalue="1.30E+00"
                     /label="C2_LCL_024-062"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="726"
                     /protein_start="682"
                     /score="1.6"
                     /tool="antismash"
                     /translation="SDVNTNALRAALTKELPAYMIPAHLIPLENMPLTLNGKLDRNAL"
     CDS_motif       complement(11317..11379)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0007"
                     /evalue="2.60E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="650"
                     /protein_start="629"
                     /score="29.3"
                     /tool="antismash"
                     /translation="LGRMDYQVKINGYRIETEEIE"
     aSDomain        complement(11347..12561)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLN47_RS17640_AMP-binding.1"
                     /evalue="3.00E-96"
                     /label="FLN47_RS17640_AMP-binding.1"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="640"
                     /protein_start="235"
                     /score="314.4"
                     /specificity="substrate consensus: Orn"
                     /tool="antismash"
                     /translation="FEAKAEEIPEHIAVIDNETEISYRLLNERANRLARTLQNRKGPKP
                     TVAVLAKRSIDAIVGVLAVMKAGGVYIPIDSHYPKARIEYILRDSGADILLLQRELKHL
                     ISNSPESEMSHIFLDDEGSYEESNCNLNLSPALEEPVYIIYTSGTTGAPKGVIVTYRNF
                     THAALAWRQIYELDRKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEI
                     YKIMNSQRITVMESTPALIIPVMEYVYRNQFKLPDLDILILGSDMVKAQDFKTLTDRFG
                     QSMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPIGV
                     AGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGSIRLLGRMD
                     YQVKIN"
     CDS_motif       complement(11464..11553)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0006"
                     /evalue="1.30E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="601"
                     /protein_start="571"
                     /score="46.2"
                     /tool="antismash"
                     /translation="PIGVAGELCIGGAGVAKGYHHKPDLTQMKF"
     CDS_motif       complement(12085..12138)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0005"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="394"
                     /protein_start="376"
                     /score="24.0"
                     /tool="antismash"
                     /translation="YIIYTSGTTGAPKGVIVT"
     CDS_motif       complement(12337..12378)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0004"
                     /evalue="7.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="310"
                     /protein_start="296"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LAVMKAGGVYIPID"
     CDS_motif       complement(12901..13020)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0003"
                     /evalue="6.00E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="122"
                     /protein_start="82"
                     /score="66.9"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPVFDAMFIL"
     CDS_motif       complement(13069..13158)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0002"
                     /evalue="1.40E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="66"
                     /protein_start="36"
                     /score="49.5"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       complement(13168..13221)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLN47_RS17640_0001"
                     /evalue="3.60E-02"
                     /label="Cy4"
                     /locus_tag="FLN47_RS17640"
                     /protein_end="33"
                     /protein_start="15"
                     /score="7.3"
                     /tool="antismash"
                     /translation="TLYMVLLAAYTAFLSRLS"
ORIGIN
        1 tagctcagcc gctcctttgg atacgcagga tcaagcggca aatacgcccc tccggccttc
       61 aatacagcaa ggacagcgat cagcatgtca ggtgagcgtt cagacaggat accgacgata
      121 ctttcgtttg tgacgccgcg tgccgcaagg tgcgcagcca gccggttggc gtacatgtca
      181 agctcagtgt atgtcagcga accgccggaa aatcggatag ctggccgctc cggtgtgact
      241 gccgcctgtc gttcaaacag cccatgcaag gttggggctt caggtgaaac agatactgtc
      301 ctgttatttt gagaaacgat tttccgtgtt ttgtcctcat ctagcaatgt catctttgac
      361 acaggaagag atggatcaga gatgacgtca gagatcatgt gctgtaaata atcttttatt
      421 tcggacatca tatttggttg ataagtgcct gtatgaaaat gaatccgaac gtacaaagta
      481 cgccctggga tcactttgac actgcatcta taattagtta cctcttccat ctcaaaatct
      541 ttcacggaga aatcaaatga tccagcttga ttcagctcct caatctcttg ttgagtaggt
      601 gtattttcaa agacgataat atgatcaatc agctcttgtt taagagcgct ctgcgcctga
      661 atgtcatata aagggaagta actatacgct tctgcttcag tcatgtcctt ttgcattccg
      721 ctgactaggt cagaaaaaga cagaaaatca ctttggactc gaataggaat ggtattgata
      781 aaaagtccga ccatgttttc cacatctttt agctcagaag gtctgcctga tataactgat
      841 ccgaatacag catcgtcgcg acgattgaac ttttggagca tgattcccca taaagcttgg
      901 aaaacagtgt taagtgtcgc accacatgct gcagcgattt tctgtaattc ggaggtttct
      961 ttttcaggaa tggtaaacgt gatctgctgt aatgtcccat ccgacatttg atctgttctt
     1021 ttaggcagag gcgaagcttt ttcgaaatgc tgaagccttt ttttccaata ctcagctgct
     1081 tcttcacgct cttgctgcat cagccattta atatacgtcc cgtacggctg tacgggaggc
     1141 aaatcaggaa attgcccttt tccaagcgct tgataaatat ggagaaagtc tttaatgacg
     1201 atgcctaaac accagccatc cattaaaata tgatggtggc tccagataca gacataatga
     1261 tcaggcgccc attttaaaat agatattctc atcagtacat ccgtttggag atcaaagcct
     1321 tttgatttgt cctgttcttt gaatgcctct gtacaatgtt ctttatcttt ttcattgaga
     1381 tgagaaatat cttcaacatg aacatggcaa tgacgttgct tgagcacgac ttgacgaggt
     1441 ttggctacat ttttatagat gaatgctgtt cgaaagatat cgtacctgtc aaaaacagca
     1501 tccatacttt tctggaaacg ctccaagtca agctgtccat tgatcgtaaa agaagcctgt
     1561 tcaaaataag ctctcgactg ctcatcatac aatgagtgaa aaagcatccc ttcctgcata
     1621 aatgacaaag ggtatatatc ctgtatttca ggttgctgcg gcatcagtga atctcctctc
     1681 ctatagtttg ttgacggctc ccatgatctc actcaattca tcaagcgtta agtcttcatc
     1741 agtgaaatca gatgcgctcc actctcggtt ttctttgccg gtacaatgct caatgatgtt
     1801 ttccagagtc tgtttaaaat gcctggaaaa tgtttggatt gttttttcct caaattgaac
     1861 cctgttatag atgatgtgca tgttcaggca ccccgaagaa acggcgccgc tgatatccag
     1921 tgcataagga cgctcccagt tcgggctgat ctcatttcct ggcttgatgt cagacacctc
     1981 aaaggcattt gattgaatat cctgatcaaa ctggcctaaa taattaaagc tgatttctgg
     2041 gctgtttttc tgagagcccc atcttttgct gatatatttc agcacgccgt agcccgcgcc
     2101 tttatgcggt atacggtgca gcatatcttt tgtctgttta ataaggtggc ccagccgctc
     2161 ttctttgtcc ttatgatcgg aatctctcat atcaagccac acaggataaa tagaggtgaa
     2221 ccagccaaca gttctgctaa tatcgatgtc ctcaagatat gattcccttc cgtggccctc
     2281 catgctgatt ttaaattggt tatttcccgt ccatttctgc aaagcaagac ctaaagctgt
     2341 cagaaggata tcattcatct ccgtgctgta agctttatgt gcagccgtta gtagtaattc
     2401 tgtgtgatgg cgagatagct caaaatcaat cacttctgta tctttgaatg tgttagatgc
     2461 tgcgtcattg tcttttggaa taggctggat gtgacggctc tcgcactcat cccagtacgc
     2521 tgcttcgcgc tgcacctggc ggcttttaga gtagtcaact attctttgtg aatacgttaa
     2581 atatgaatct gttttttgcg gcagtttaat agattctcct gagactgcct gtttgtaagc
     2641 agctgaaaaa tcctcgaaca aaatgcgcca ggaaaccgca tcaacaacta agtgatgaat
     2701 cgtcagaaat aaatggtcac cattctcggt tctaaacaat ccagcgtgaa gtaaggggcc
     2761 ggtttccaaa cgaatatgtt cttgcatccg gctggctgct tcctcaatcg tgtaccgtgc
     2821 ttctgttagg ctatccttta catcaaacag ttcaagtgca tatagctcct catctgaaag
     2881 atctattcct ctgtttatct gcacctgcct gccatcttca tgccggcata cgattctcag
     2941 tgcatcatga tgagtcacaa ggctttttag tacttttcta agcgcagcct catcaaatcg
     3001 ttcagcccgg tagatcataa cggactggtt aaaatgatgg ctttccagag attgcgagaa
     3061 aaaccactgc tggataggtg tccaagtaat ctcgccttcg accgggcctt ggtcaatggc
     3121 gcgtacgtct tttcgaaccc gggcggacag ttcaccaaga gtctgatgtt caaacatctc
     3181 gcgtactgtc gtttcaaatc cgcgctgctt cagtctggca caaacctgca gcgctttaat
     3241 agagtctccg ccaagctcaa agaaattggc gcttacaccc agctcatcta cattaagaag
     3301 ctcctcccaa atttcagcca tcaccgtttc aatctcattt ctaggactga tatcatcagc
     3361 tgtataagcg tgtttttcag gctctggcag ggctttctga tcgagctttc cattaacagt
     3421 caccgggatg ctgtcaattt gtatcatacg ggcaggcagc ataaagtcag gcaaggcgtt
     3481 ttttaggtaa gttcggatgt ctgatatatt cgcagcctgt tgatctttta tcaccatata
     3541 tgcatatata gctgtttgcc cttgctcgtc tgctctggta atgacagccg cctctttaat
     3601 cattggatac tgaagaagtg ccgcttggat ttcgcctaac tcaatacggt gccctctgac
     3661 tttcacctgc tcatcaatgc ggcctaagta ttccagctcg ccatttgaca ggcgcttagc
     3721 aagatctcct gttcggtata atctgtctcc cggaagataa ggattggata caaaacggtc
     3781 agcggtcagc tcatctctgt tgagatatcc ccgtgccaca ccttcgccgc ctatatacag
     3841 ctcccctgga actccgatcg gctgcagatt catatgagca tccatcacat aagcctgcag
     3901 agttgaaagc ggccgtccga tattgctttt attttttaca atgtctgctg cggacaattt
     3961 tttgaatgtt acatggaccg ttgtttctgt aataccgtac atattaatca aatcagtatg
     4021 aggatatttt ttattccagc tttgaagcat gccgggctgt aaggcttcgc cgccaaaaat
     4081 cacgtagcgg atgtttaaat gatctgtatg attttgatct tcaagcatca agccgtaaaa
     4141 agcagtcggg gtctgattga gtacagtgac gcgctctttt tttaataata aacggaatgc
     4201 atgggggtca cgggctgttt ctttagagac cacgactaat gtacctccgt tcaataacgc
     4261 accgaacatc tcccatacag agaaatcaaa gcaataagaa tgaaataacg tccagatgtc
     4321 ttcatggtta aattcaaaag gcaggttttg atgcttcaag agactgatca cattgcggtg
     4381 ctcgacaatg actccctttg gctggccagt cgttccagat gtgtatatca cgtatgcggg
     4441 ctgatctgtt actatttctt gaatgtttac atcagccgga aatgagtcgt tttcacattc
     4501 atcgatatac aaaatatgcc cggtgtagtc tgcaggtttg ttttgaccgc gctctgtcag
     4561 cagcagtttt gctccgctgt cattaagcat aaagctaata cgctccttgg gatattcagg
     4621 atcaatcggc aaataggccc cgccagcttt taaaatcgat aaaacgccaa tgatcatatc
     4681 aggtgaccga tcgagcatca gaccgacgat atcgccagtt ctcacccctt gtttgatcag
     4741 catagcagct gcccgctcgg ctttttcatt caggtctcga tacgtaagct gagaatggcc
     4801 gcacaccact gcgatatgct ccggatattt agcggcttgc ttttcaaata agcttactat
     4861 gttttcattt ctcggataag ccgcatactg tcccattttt tcaaggagca acctacgctc
     4921 tgcagcagga agcaattgca tgtccgaaat tctcatctcg gtatccgccg ttaccccttt
     4981 caccaattca ataaaatagg atgcccactg cgtaatggtt tcttcttcaa aaagagcagt
     5041 gctgtattca aaacggcagc gtattccact cggatgctcc tcagcgtgta atgttaaatc
     5101 gaatttagat atatcatgtt taggagtgac agacgaaatc gacagaccag gcacttcgaa
     5161 ccggaaatct tcactgcttt gaagcacaag catcgcatcg aacagcgggt tgcgatttac
     5221 ctctcgattt gtaaagagct tatctgccag ctcctcaaaa ggataatcct gatgctcgta
     5281 agctgtcaga gccaggtggc gaatgtcctg caaataggag ctgaacgttt tgtggccctc
     5341 gggcttgctg cgcatcgcca atgtattgac gaacatcccg atgacgcgct ccagatcagc
     5401 gtgcggtctt ccggcagcag gcgaaccgac aacaatatcc tcttgcccgc ttagcttaga
     5461 taacaaaata gaatagacag ccagaagaat catatacaat gttgttcccg tttcagccat
     5521 taaacggtgc agctcatcag ccgtgtcttt atcaatgttg agttcaattg ttccaccgct
     5581 gaaatcaggg agacgcggcc ttgttttatc aagcggtaat tctagtgtag gaagactccc
     5641 gccaagctga ccgagccagt aggcctcctg ttttttgtat agctctttcg ggtgcttctc
     5701 ttgctgccaa acagcaaaat ccttataatg caggtttaaa gctggcaact cttttccgca
     5761 atataagtca gtaaattctt ggacaagagt gctcatcgag acaccgtcgg caataatatg
     5821 gtgcatatcg agcagcaaaa agccgcgatt attgcccatt gtaatgacac atgctctaaa
     5881 aagcggaccg gatgatagat caaacggttt gataaaggtc tcgattgcag actcaagcat
     5941 ttgttctgat tccatttcaa gctcttttag atcaaaagct atctctggat aaatgatctg
     6001 cacaggctcg tctctgtcaa gcacaaaaac agtccgtaat gcttcatgcc gattcacaag
     6061 ttctgtgaga acgcttctca accgctggcg attcagattt ccgcgtaatt caagtacagc
     6121 tggcatgttg tagcctgtgc tgtcatctgc cagctgatga agagcatata atcgtttttg
     6181 cgagaaagac agcggataga catctctttg atccgcaggt tcaatctgtg taaaagcgtg
     6241 ttcttttaag ctcatcaatt tgaccgccat gctttcaacc gtcggatatg aaaacacctc
     6301 actgagcggc agctcgacat taagcttttt atgtattctt gataccagtg cggccgcttt
     6361 taaggactgt ccgcctaact gaaagaaatc atcacgaatg ccgatttgct gtttattcag
     6421 cacatcttcc caaatatgtg cgagatcagc ttcgattaag gttcggggcg ccatatatgt
     6481 gacactcgta ttgttttctg gttcaggaag cgcaaacctg tcaagcttgc cgctggatgt
     6541 taatggcatc cggccgatgt tgataatact tgctgggatc atataggacg gcaatgtccc
     6601 ggcaagatgc tgatacaaat ctgggaggct gtttcccttt tctggaacga tataagcaac
     6661 aagctccttt tcctcagcag aaacatcacg ggccagtacc gcggcttctt ttaccccggg
     6721 tgcttgtcga agaactgttt caatctctct cagttcaata cggtaacccc taatttttac
     6781 ttgatcatca aaacgtccaa tatattcaat cgttccatca ggcaaaaagc ggcctgcatc
     6841 acctgttcgg tataaacgct ccccttcaag gaatggatga tcggagaatg ctttctgtgt
     6901 cagctctggc tgtttgtagt atcctctcgc aagacccgcg ccggaaatac acagttcacc
     6961 cgccgcgccg atcggctgca tttgatttcc gtgcaaaaca aatacttttg tgtttctgat
     7021 cgggtgtccg atcgtgatcc tctctttttc attcagatgc cgcaatattg ttgttgccac
     7081 actgttttct gtgggcccgt attcatttgc cagttcagca gaaggacaaa ttatttgact
     7141 caactcaagc agatcaggcg tgaccgcttc acccgcaaat gtcacaatac gaagactttt
     7201 tgcatcgtca gcagtcatca cttccaataa caccctgtac agggaaggaa caatgatcat
     7261 gtggctgacc ttataacggg ctatttttcg cttaagggcc agcacatcct tcgcttcgtc
     7321 atctgttgtc agcagtacgc acgcaccgga taaaagtggg gtaaataagc tcgtcacaca
     7381 gccgtcaaac acgtacgaaa acaaatggag ggatatatcc tgttcggcca tgccatactc
     7441 ttcccgtctc cattgcaatg tattggcaat accgtgatga tcaactaaaa cccctttagg
     7501 gcgccccgtc gttcccgacg tatagatcaa gtaggctaga tcacctggcg gcatatttgg
     7561 agcttctgtt tggtaacttt ctgtatgttc tatcgttatc gtatttcctt cataggacgg
     7621 agggatcaag gaaataaggt cttcttctat cagcaattga gccgcttgac tgtccttcag
     7681 caggaaagaa agacgttctg ctggaaaatg tggatcaagc ggcatataag cgccgcctgc
     7741 tttccaaatc ccaagcagag ctgcaggcat ttccattgac cggcccatca ttacagcaac
     7801 gatatctcca gatccaacgc ctttttctat cagagcgtgc gcaatctgat tggctcttac
     7861 ttgtaactgg cgataggtcc agcattcgtt tcccattttc aatgcagcag cttcaggtgt
     7921 tttgtgagct tgttcctcga acaattgagg tattgttttg ttcacataag gacgctcagt
     7981 ttcgttaaac gattggataa cctgttgctc ctccggcggc acgatattga tgtcactgac
     8041 ggcaacatcg ggatttgtca aaatgcaatc cagtgcttgc tttagatgcc cctgaattct
     8101 cagcatctcc tcccgctcgt aaacgtctgc gttgtagctg aatttgatat aaaatgattc
     8161 tcccggaacg ataacgatat taaagtcgta attggtttgt tccgacattg aaatgtcact
     8221 cagcttcaga gcgccttcgt cattttcact ctccacgctt aatgcctgat gaagctgtac
     8281 agggtaattt tcaaaaacaa aaatatgatc gatcaaccct tgcttcaatg gactatggtt
     8341 ttgaatctca taaagcggat aatagccatg ctgttcagat gataaaatat cctcctgtac
     8401 ggctttgacc agcgaagaaa acgttatgcc ttccgcagat cggattcgca ctggaacagt
     8461 attgataaac aagccgacca ttgattcaat cccgtcaatc gctgacgggc gtcccgaaat
     8521 gacggagcca aaaacggcat catctgcagc attatatcga tggagcagca cgccccaaat
     8581 actcataaac agcgtgttta atgtcactcc ccagttttgg gcagcctctg tcagtttctc
     8641 aaccatatcc gacgctaatg aaaagctgac ctggtcggct ttataattcc cgtctgccgt
     8701 gcggcgcttt attcggggaa tagaagcagt attgccgtac tccttcaaat attcgctcca
     8761 gtaggcagca gtctcttctt gatcttgttc tccgagccat tcaatataac ggctgtacgg
     8821 caccgtgctg ccaagctgta caggtgagtt atttttgagc gaatcataca tgctgaaaaa
     8881 ctctttaaga ataatgccga gacaccaccc atccatgatg atatggtgat gtgtccagac
     8941 acatgtatat tggctgtctc ctctatcaaa aagggcaaga cgcattaaag gatctttttg
     9001 caaatcaaat cctttttccc gatccttagt cataaaagca tcaatcagcg tctgctgttc
     9061 ttgatcagcc aggcgagaaa tatcttctct atatactgtc aattcccggt ttgataagac
     9121 tacctgctgc ggacctgtaa gatctggtac ttctttaatg aaaatcgttc tgaaaatatc
     9181 atatctagaa acaagaaggt ttaagctctt ttgaaacgag tcgacgcata gattccctgt
     9241 gatcgtaaac gaggtctgtt cgatatatgc tttcgagctg aaatccatta gtgaatgaaa
     9301 cagcattcct tcctgcatgt gcgataacgg ataaatatct tgaatttgtg ccgattgtgc
     9361 catcaattcc acacaccttt tcaaaagtta aagatctttc acgagatctt cgatgctaga
     9421 taatgcagac aacgttaatt ccttattgct gaaatcgctc aatgtttttt cgcgtgcttt
     9481 tttctgcgaa caatgctcaa tcgtctcgat aagatgcctg tgaaaacgat ccataaagta
     9541 ctcaattgag tgtttgctga acacctgggt gtataccgct tttacttgaa gccgtccgtc
     9601 cgtaatgaga gcattgatgt ccagctcata ctctcgttct ctcttacccg ctatttcgtg
     9661 acggggcttg taatatgata attgaaacgt ttcagcttct ttctcttcgc taaattgacc
     9721 gagataatta aagctgacct caggctcttt atgccgcagt tctcctatgt gtgttaacaa
     9781 tccgtatcca gttcctttgt tcggtactct tctcagcata tcttttgtcg tcttaattcg
     9841 gtatgcgagc tgatcctcga aaggctcggg aatacccatg tctagcaaaa taggataaat
     9901 ggaggtaaac catccaacgg tccttgaaat atcaatgttt ggcacatgcc cttctctgcc
     9961 gtgtccctca gtgctgatca cgatttggtc atgccctgtc cattcagaaa gcgccattcc
    10021 taaagccgta agcaaaagtt cgttggcatc agtaccatag gcttgctggg tttcaaacag
    10081 caatttttca gtccagtccc cggatagtac aaacgcagct gcgtcgctgt tcatttggag
    10141 tctgtccggc acattttcta tgtccttagg aagaaaagca gtgtgagcgt ctaaaatcgt
    10201 ttgccaatac ggtttctctg aaagcaattg tttactttca gctatttggg taagaccatc
    10261 ggcgtaggat aaataagaat ccgtttttgg cggtaattgg atttctttct tttctaaagc
    10321 ctgttgatat gctgcagcta aatcttcaag cagaattctc caagaaacgc catctatcac
    10381 aagatgatga agtgcaatca gcaaatgatc cccttctgcc gttttaaaca agcctgcttg
    10441 cagcaaaggc cctttttcta cattcatttt gctttgaatg acggtttcct cagcggcaag
    10501 tttttcatca agatgagccc tttccagcga tgcttttgtc caatctgaaa tataaaggcc
    10561 aaacagttca tgatccttgt gattgattcc gcgattaaac tgaatgacat ggccgttttg
    10621 gtcatgttgg aaaatcatgc gaatggcatc atgatgctcg gttattttac gcagcgctag
    10681 atgaagcgcg ttagcattga atcctttttc actgaaaagc atgacggact ggttgtaatg
    10741 atagtgaaaa gcatgtacct gtccgaaaaa tcttcgctga atcggggtga gttcagcttc
    10801 accttccgca ggtccctggt ccgcttgaga tgccaatggt gtgatatgtc cgcatagttc
    10861 ctgaatcgtt gaataacgga ataagtcgcg tattgtcatg ctccagcctt cagcggccag
    10921 acgtgctgcc acttgtaatg ctttaattga gtctccgcca agctcaaaaa aggaatcgtg
    10981 aatgccgact cgtggcatgc tcagtacatc ttcccatata tacgccatcg ttttttgtat
    11041 gtcgttaact ggtgcggtat atggacgcga taacacatta tttggagccg gcaaggcatt
    11101 tctgtccagc tttccgttta gggtcagcgg catgttttct aaaggaatca gatgtgcagg
    11161 aatcatatac gctggcagct cctttgttaa agcagcacgg agagcattcg tattgacgtc
    11221 tgaaggcaca atatatgctg ccaaaccagc ctgtccattt ttatcatgct gaacggcaac
    11281 agcagcttct ctgacaagcc ctgtttgaag cagaacactt tcaatttctt ctgtttcaat
    11341 tctgtatcca tttatcttta cttgataatc cattcggcca agaagccgga tcgacccgtt
    11401 tggaagccag catgctcgat caccggttct gtacagcctt tctccagaga caaatggatt
    11461 ttctgtaaat ttcatttgcg ttaagtcagg tttatgatga tagcctttcg caacacctgc
    11521 cccgccgatg cacagctcgc cggcaacacc gatcggctga atttgatcag tctggctgag
    11581 tacatacatg tgtacattcg gcagcgggct gccgattggt acgttatctc ccgtacactc
    11641 tccacccata ctagtttcat agaaactcga atcaatggtt gcctctgtga caccatagct
    11701 attaatgatg cgcatgcttt ggccaaagcg atctgtcaat gttttgaaat cttgagcttt
    11761 caccatgtcg gaaccaagaa tcagtatgtc taagtcagga agcttgaact ggttacggta
    11821 tacatattcc atcaccggga taatgagagc cggtgtcgac tccatcaccg tgattctctg
    11881 agagttcatg attttatata tttcagcagg ttccagccgt gtttcatctg ggcaaacgat
    11941 tagagtcccg ccgttggtca atgttctcgc caaatctcct gagaagacat cgaatgaaaa
    12001 gctcgcgatt tgaagcagtc tgacaggctt ccgatccagc tcataaattt gacgccaagc
    12061 aagagcagca tgagtaaagt tccgataggt gacaataacg cctttaggcg cacccgtcgt
    12121 tcctgacgta taaatgatat ataccggctc ttcaagagca ggagataagt taaggttgca
    12181 gttactttct tcataagagc cctcatcgtc aaggaagatg tgagacatct cagattcagg
    12241 cgagttcgaa atcaaatgct tcaactctct ctgtaaaaga agaatatctg ccccgctatc
    12301 acgaagaatg tattcaatac gagcttttgg ataatgtgaa tcgattggga tatacactcc
    12361 gccagctttc atcactgcca gaactccaac aattgcatcg atggaccgct tggctaaaac
    12421 agccacagtt ggcttcggtc cttttctgtt ttgcaatgtt cgtgccagac gattggctct
    12481 ttcatttaga aggcgatagc taatctctgt ttcgttatca ataacagcta tatgttctgg
    12541 aatttcttca gctttcgctt caaatatgtg atgaaaagga acatcttttt gagcaaattc
    12601 aacctgagtt ttgttaaatc caaagactat tttttgtttt tctttatcac taagtatgtt
    12661 tatttgtgca aggcttgttt caggagttga aagtgccgca tgcagaaatt cgataaaatg
    12721 atcggcccag cgttcaattg tagctttcag gaatacttct gtactgaatt ccatttcaca
    12781 gcaaatagat ccatttattt ccgtagctat taatgtgata tcaaataagg aaatgtgatg
    12841 tgcgaaattg gcaggccgga cttttatttc tctcagatct atgtcttgtt tttccacatt
    12901 ttgaaggata aacatcgcat caaacactgg attccggctc atatcccgtg tcaattcaag
    12961 cttatcgaca agttcttcga acgggtaatc ctggtgctca aaggcttcca atgctgtctc
    13021 acgcacttcc tgcaaatact gtacgaatgg cttcccgccc tccgggcgcg tccgaagcgc
    13081 cagcgtgttc acaaacatgc cgagtatcgg ctcaagatcc ttgtgcggcc ggccggcaat
    13141 tggcgagccg acgatgatat cttcctgtcc gcttaagcgt gacaagaacg cggtgtaagc
    13201 cgcaaggagc accatgtaca gtgtgcttcc gttttctcgt gccagcttgt gaaggcctga
    13261 tgcaacctct
//
