LOCUS       NZ_VIOH01000002        20891 bp    DNA     linear   CON 03-JUL-2024
DEFINITION  Bacillus subtilis strain FH1 NODE_2_length_1007480_cov_130.497986,
            whole genome shotgun sequence.
ACCESSION   NZ_VIOH01000002
VERSION     NZ_VIOH01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1007590)
  AUTHORS   Khan,M.A., Khan,M.N., Imran,M., Hameed,A. and Hasan,F.
  TITLE     Draft genome of Bacillus subtilis FH1 isolated from tannery waste
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1007590)
  AUTHORS   Khan,M.A., Khan,M.N., Imran,M., Hameed,A. and Hasan,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2019) Department of Microbiology, Quaid-I-Azam
            University, Facutly of Biological Sciences, Islamabad, Federal
            45320, Pakistan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 90.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_012028945.1-RS_2024_07_03
            Annotation Date                   :: 07/03/2024 03:57:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,286
            CDSs (total)                      :: 4,159
            Genes (coding)                    :: 4,053
            CDSs (with protein)               :: 4,053
            Genes (RNA)                       :: 127
            rRNAs                             :: 10, 16, 11 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 7, 16, 11 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 62 of 106
            Pseudo Genes (incomplete)         :: 50 of 106
            Pseudo Genes (internal stop)      :: 18 of 106
            Pseudo Genes (multiple problems)  :: 21 of 106
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:36:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 608083
            Orig. end                         :: 628974
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VIOH01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10891](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            523..729
                     /gene="spoIIIAC"
                     /locus_tag="FLN47_RS08565"
                     /old_locus_tag="FLN47_08695"
     CDS             523..729
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390321.1"
                     /locus_tag="FLN47_RS08565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08695"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_003153142.1"
                     /transl_table=11
                     /translation="MGVDVNVIFQIAGVGIVVAFLHTILDQMGKKEYAQWVTLLGFIYI
                     LFMVATIVDDLFKKIKAVFLFQG"
     gene            736..1137
                     /gene="spoIIIAD"
                     /locus_tag="FLN47_RS08570"
                     /old_locus_tag="FLN47_08700"
     CDS             736..1137
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390320.1"
                     /locus_tag="FLN47_RS08570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08700"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_003230228.1"
                     /transl_table=11
                     /translation="MQIDIVQIVGLGLIATFLSLIVKEQKPTFAFLIVVFAGCAIFLYL
                     VDQIYDIIRMIEKIAINANVNMVYVETILKIIGIAYIAEFGAQLTKDAGQGAIASKIEL
                     AGKILILVMAVPILTVIIETILGLIPSMS"
     misc_feature    complement(1155..1169)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.21"
                     /tool="antismash"
     gene            1156..2355
                     /gene="spoIIIAE"
                     /locus_tag="FLN47_RS08575"
                     /old_locus_tag="FLN47_08705"
     CDS             1156..2355
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390319.2"
                     /locus_tag="FLN47_RS08575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08705"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_072175554.1"
                     /transl_table=11
                     /translation="MKRFQWVLLLAVLIIAGRAEIVQAAGNAEQTEDHAETAEQLAERT
                     AASLETDKIGEFWNDIMTEYGGLLPESQKGSLMEFINGDKSFSPQEWLKALFSYLFHEV
                     LANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYSIVYMVLIILALNSFHVAINYA
                     TEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMPLIFL
                     SAILSIVSTMTDQYKVTQLANLLRNIAIGALAVFLTIFLGVISVQGASAAVTDGITLRT
                     AKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVAILICIAAFPAIKVLSLAFI
                     YKLAAAILQPLGGGPVITCLDVISKSVIYIFAALAIVSLMFFLSLTVIITAGNLTMMMK
                     "
     gene            2369..2989
                     /gene="spoIIIAF"
                     /locus_tag="FLN47_RS08580"
                     /old_locus_tag="FLN47_08710"
     CDS             2369..2989
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390318.1"
                     /locus_tag="FLN47_RS08580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08710"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_003230233.1"
                     /transl_table=11
                     /translation="MSFLTEWLTTIVLFILFAIVIDMLLPSSSMQKYAKMVVSLLLIVV
                     MLTPIFKLFKTDPEVIFEYLTKNGQSESADIKNQINSKKIEIQASQRAYILEEMAVQLK
                     KKAEERFSHDEYKVGRIKLTAGEKVDSEEDIKTISVYMAPSSEKTVQTVAPVHIDTDHA
                     YVTKEAAEQKEAKQIQTQLADIWEIGSEKITVHMEGGESVGNE"
     gene            2982..3671
                     /gene="spoIIIAG"
                     /locus_tag="FLN47_RS08585"
                     /old_locus_tag="FLN47_08715"
     CDS             2982..3671
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390317.2"
                     /locus_tag="FLN47_RS08585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08715"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_014477307.1"
                     /transl_table=11
                     /translation="MNKNGLWNVLKKQFLPGQTKDGEKPKLTKYHYFLFVFVLGVSFML
                     VSQLFSSPEKTENAKTITAVSSQHSADSKEKTAEVFKASKSDKPKDSIDDYEKEYENQL
                     KEILETIIGVDDVSVVVNVDATSLKVYEKNKSNKNTTTEETDKEGGTRSVTDQTSEEEI
                     VMIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQIKQTIIEAVTRVLDVPSHRVAVAP
                     KKIKEDS"
     gene            3672..4328
                     /gene="spoIIIAH"
                     /locus_tag="FLN47_RS08590"
                     /old_locus_tag="FLN47_08720"
     CDS             3672..4328
                     /codon_start=1
                     /gene="spoIIIAH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390316.2"
                     /locus_tag="FLN47_RS08590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08720"
                     /product="stage III sporulation ratchet engulfment protein
                     SpoIIIAH"
                     /protein_id="WP_003230250.1"
                     /transl_table=11
                     /translation="MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMQSEKSASDSG
                     EVATEKAPAKQDTKEKSGTETEKGKEDGTKGTKDSSADKETSAEASEKGTVVTETADDD
                     LFTTYRLDLEDARSKEREELNAIVSSDDATAKEKSEAYDKMTALSEVEGTEKQLETLIK
                     TQGYEDALVNAEGDKINITVKSDKHSKSKATAIIDLVAKEIKTMKDVAVTFEPSK"
     gene            4484..4963
                     /gene="accB"
                     /locus_tag="FLN47_RS08595"
                     /old_locus_tag="FLN47_08725"
     CDS             4484..4963
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390315.1"
                     /locus_tag="FLN47_RS08595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08725"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_003230252.1"
                     /transl_table=11
                     /translation="MLNIKEIHELIKAIDESTIDEFVYENEGVSLKLKKHEAGTVQVMQ
                     QAPAAPVQAQAPQAVQPQAQQAAAPAQEAPKQDENLHKITSPMVGTFYASSSPEAGPYV
                     TAGSKVNENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE"
     gene            4975..6327
                     /gene="accC"
                     /locus_tag="FLN47_RS08600"
                     /old_locus_tag="FLN47_08730"
     CDS             4975..6327
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390314.2"
                     /locus_tag="FLN47_RS08600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08730"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_003230253.1"
                     /sec_met_domain="RimK (E-value: 2.9e-07, bitscore: 26.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 9.5e-09, bitscore:
                     31.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.9e-10,
                     bitscore: 36.6, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.5e-06, bitscore:
                     24.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLLIANRGEIAVRIIRACRELGIETVAVYSEADKDALHVQMA
                     DEAFCIGPKASKDSYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEEVNVTFVG
                     PSADAISKMGTKDVARETMKQAGVPIVPGSQGIIENVEEAVSLANEIGYPVIIKATAGG
                     GGKGIRVARTEEELINGIKITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNYGNTI
                     HLGERDCSIQRRLQKLLEESPSPALDSEIREQMGDAAVKAAKAVGYTGAGTVEFIYDYN
                     EQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGMELSLKQEDVEFEGWAIECRI
                     NAENPSKNFMPSPGEIKMYLPPGGLGVRVDSAAYPGYSIPPYYDSMIAKVITYGKTRDE
                     AIARMKRALSEFVIEGIETTIPFHLKLLEHETFVSGEFNTKFLETYDVMGS"
     gene            6348..6755
                     /gene="yqhY"
                     /locus_tag="FLN47_RS08605"
                     /old_locus_tag="FLN47_08735"
     CDS             6348..6755
                     /codon_start=1
                     /gene="yqhY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390313.2"
                     /locus_tag="FLN47_RS08605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08735"
                     /product="fatty acid biosynthesis protein YqhY"
                     /protein_id="WP_003230254.1"
                     /transl_table=11
                     /translation="MKDNSLLKMDHEDTHLGKVEIAPEVIEVIAGIAASEVDGVAEMRG
                     NFATGVVERFGKVNHGKGVKVDLADDGITIDVYCVVTFGVSIPKVAASVQENIRQTLLN
                     MTSLSINEINIHIVGIQFDTKAQEVQIDEEM"
     misc_feature    complement(6775..6789)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            7018..7413
                     /gene="nusB"
                     /locus_tag="FLN47_RS08610"
                     /old_locus_tag="FLN47_08740"
     CDS             7018..7413
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390312.2"
                     /locus_tag="FLN47_RS08610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08740"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_003230256.1"
                     /transl_table=11
                     /translation="MKRRTAREKALQALFQIDVSDIAVNEAIEHALDEEKTDPFFEQLV
                     HGVLEHQDQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAIEL
                     AKRFGDDKATKFVNGVLSNIKSDIEQS"
     gene            7425..8276
                     /gene="folD"
                     /locus_tag="FLN47_RS08615"
                     /old_locus_tag="FLN47_08745"
     CDS             7425..8276
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390311.1"
                     /locus_tag="FLN47_RS08615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08745"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_003230259.1"
                     /transl_table=11
                     /translation="MTATIIDGKETAREKREQLAKEVEELKKQGVTPGLAVILIGDDPA
                     SHSYVRGKKKAAETMGMNFKLDQFDSSLTEAELLSIIDQYNQDPEFHGILVQLPLPDHI
                     SEKAVIERISPDKDVDGFHPLNVGKMLLGEDTFLPCTPHGIVELLKKTNIDLSGKEVVV
                     VGRSNIVGKPVGQLLLNENATVTYCHSRTENITEHTKKADILVVAVGRANFISADQIKE
                     GAVVIDVGVNRLENGKLCGDVEFEGAKEKASFITPVPGGVGPMTITMLAHNTVKSAKRT
                     LS"
     gene            8414..9760
                     /gene="xseA"
                     /locus_tag="FLN47_RS08620"
                     /old_locus_tag="FLN47_08750"
     CDS             8414..9760
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390310.2"
                     /locus_tag="FLN47_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08750"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_015251733.1"
                     /transl_table=11
                     /translation="MGEAAYVTVSALTKYIKRKFDVDPHLENIWIKGELSNVKIHTRGH
                     IYFTLKDENARMQSVMFARQSERLPFKPENGMKVLVRGGISVYEPSGNYQLYAKEMQPD
                     GVGALYLAYEELKKKLAGEGLFDDRYKKQIPAFPATIGVVTSPTGAAVRDVITTLKRRY
                     PLVKVIVLPALVQGENASRSIVTRIEEANEKEICDVLIVGRGGGSIEELWAFNEEIVAR
                     AIFASNIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLIERTKTAEVRMT
                     RAMQQHLGQKKERIQTLQSSYAFRFPKRLYAQKEQQFDLAYQQFQAQLTALLDRKSRQL
                     ERETYRLEALHPHEQLKQARTRYQEQTNQLRKNMNIQMKQLHSQFQTVLGKLNALSPLQ
                     VMERGYSLAYKEDKLIKSVSQIEEQDRLEVKLKDGVLTCEVLEKRGEEK"
     gene            9757..10011
                     /gene="xseB"
                     /locus_tag="FLN47_RS08625"
                     /old_locus_tag="FLN47_08755"
     CDS             9757..10011
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390309.2"
                     /locus_tag="FLN47_RS08625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08755"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_003226409.1"
                     /transl_table=11
                     /translation="MTDVKKNENMTFEEAMKGLESIVSKLEEGDVPLEQAINYFQEGMA
                     LSKMCHEKLQKVEKQMDFILKEDGELAPFSVQEEDEGDK"
     gene            10001..10891
                     /gene="ispA"
                     /locus_tag="FLN47_RS08630"
                     /old_locus_tag="FLN47_08760"
     CDS             10001..10891
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390308.2"
                     /locus_tag="FLN47_RS08630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08760"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_072175555.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.9e-64, bitscore:
                     211.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKLTSFLADRKKTIENQLSVYTEKLDMPDSLKKSMLYSLQAGG
                     KRLRPLIVLAVLNAYGKSEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHK
                     VFGEATAVLAGDGLLTESFKLITSHVSDEVSAEKRLRLVNELISAAGTEGMVGGQVADM
                     EAENRQVTLEELESIHERKTAKLLGFCVIAGAILADAPEEDIETLRTFSSHIGIGFQIR
                     DDILDLEGSEEKIGKRVGSDTTNDKSTYPSLLSLEGAKHKLDVHIKEAKRLIGGLSLQK
                     DLLNELCDLIAARDH"
     gene            11066..12967
                     /gene="dxs"
                     /locus_tag="FLN47_RS08635"
                     /old_locus_tag="FLN47_08765"
     CDS             11066..12967
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390307.1"
                     /locus_tag="FLN47_RS08635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08765"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_015384069.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.5e-117,
                     bitscore: 387.7, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLSIQDPSFLKNMSIDELEKLSDEIRQFLITSLSASGGHIGPN
                     LGVVELTIALHKEFNSPKDKFLWDVGHQSYVHKLLTGRGKEFATLRQYKGLCGFPKRSE
                     SEHDVWETGHSSTSLSGAMGMAAARDIKGTDEYIIPIIGDGALTGGMALEALNHIGDEK
                     KDMIVILNDNEMSIAPNVGAIHSMLGRLRTAGKYQWVKDELEYLFKKIPAVGGKLAATA
                     ERVKDSLKYMLVSGMFFEELGFTYLGPVDGHSYHELIENLQYAKKTKGPVLLHVITKKG
                     KGYKPAETDTIGTWHGTGPYKINTGDFVKPKAAAPSWSGLVSGTVQRMAREDGRIVAIT
                     PAMPVGSKLEGFAKEFPDRMFDVGIAEQHAATMAAAMAMQGMKPFLAIYSTFLQRAYDQ
                     VVHDICRQNANVFIGIDRAGLVGADGETHQGVFDIAFMRHIPNMVLMMPKDENEGQHMV
                     HTALSYDEGPIAMRFPRGNGLGVKMDEQLKTIPIGTWEVLRPGNDAVILTFGTTIEMAI
                     EAAEELQKEGLSVRVVNARFIKPIDEKMMKSILKEGLPILTIEEAVLEGGFGSSILEFA
                     HDQGEYHTPIDRMGIPDRFIEHGSVTALLEEIGLTKQQVANRIRLLMPPKTHKGIGS"
     gene            12964..13809
                     /gene="yqxC"
                     /locus_tag="FLN47_RS08640"
                     /old_locus_tag="FLN47_08770"
     CDS             12964..13809
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="yqxC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390306.2"
                     /locus_tag="FLN47_RS08640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08770"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_003230264.1"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     gene            13907..14356
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /locus_tag="FLN47_RS08645"
                     /old_locus_tag="FLN47_08775"
     CDS             13907..14356
                     /codon_start=1
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390305.1"
                     /locus_tag="FLN47_RS08645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08775"
                     /product="arginine repressor ArgR"
                     /protein_id="WP_014114358.1"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEIMGTICGDDTILIICRTPEDTDGVKNRLLELL"
     gene            14391..16121
                     /gene="recN"
                     /locus_tag="FLN47_RS08650"
                     /old_locus_tag="FLN47_08780"
     CDS             14391..16121
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390304.2"
                     /locus_tag="FLN47_RS08650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08780"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_017696435.1"
                     /transl_table=11
                     /translation="MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQEISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKLSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     gene            16296..17576
                     /gene="spoIVB"
                     /locus_tag="FLN47_RS08655"
                     /old_locus_tag="FLN47_08785"
     CDS             16296..17576
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390303.2"
                     /locus_tag="FLN47_RS08655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08785"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_021480004.1"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQPSESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYGKEKAS"
     gene            17852..18655
                     /gene="spo0A"
                     /locus_tag="FLN47_RS08660"
                     /old_locus_tag="FLN47_08790"
     CDS             17852..18655
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390302.1"
                     /locus_tag="FLN47_RS08660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08790"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_003226427.1"
                     /transl_table=11
                     /translation="MEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     gene            complement(19120..20238)
                     /gene="yqiG"
                     /locus_tag="FLN47_RS08665"
                     /old_locus_tag="FLN47_08795"
     CDS             complement(19120..20238)
                     /codon_start=1
                     /gene="yqiG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390301.1"
                     /locus_tag="FLN47_RS08665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08795"
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="WP_049141220.1"
                     /transl_table=11
                     /translation="MNPKYKPLFEPFTFKSGVTIDNRIAVAPMTHYASNEDGTISEAEL
                     DYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAIQAQGAKAVVQ
                     IHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALKEEEVENIVKAFGEATRRAIEAGF
                     DGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKAASEHAKGAFL
                     VGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRGADPTRTRMDL
                     LNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPDWTVKVKEGREKQIE
                     TVIKGTDKDKYHLPEPLWQAIVNTPGWVPYKD"
     gene            complement(20311..20463)
                     /locus_tag="FLN47_RS08670"
                     /old_locus_tag="FLN47_08800"
     CDS             complement(20311..20463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009513977.1"
                     /locus_tag="FLN47_RS08670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLN47_08800"
                     /product="hypothetical protein"
                     /protein_id="WP_014480226.1"
                     /transl_table=11
                     /translation="MKEVKAMKKFVLLLAAAVITCSIGHQISGGYKGPEKERRKHHSAL
                     KIFSR"
     misc_feature    complement(20773..20786)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.2"
                     /tool="antismash"
ORIGIN
        1 gcgctgtatt cattgtggta gcgacaacat ggacaggttt tgagatggcg aagatttata
       61 cagaacggcc gcggcaaatc cgccagctgc gtgcggcgct tcaatccctc gaggctgaaa
      121 tcatgtacgg ccatacaccg cttcatactg cttcacagca gattgccaaa cagctcgcac
      181 agcctgtttc agctcttttt tccgcattca gtgatcagct ggacaaggga agtgattccg
      241 cgaaaacggc gtgggagcaa agcttaaaga aggtatggga taccctgtct ttgaaaaaaa
      301 gcgaatacga agtgctgaag cagtttggcg agacgctcgg gattcatgat cgaatctctc
      361 agcaaaagca catcaagctg gcgctgtcac atttggaagc ctctgaagcg gatgctgagc
      421 aggcgcaagc gaaaaatgaa aagatgataa aaagtttggg ctttttagcg ggcttgttac
      481 tcattcttct attgatgtaa acgtgagggg agcaaaaata aaatgggagt agacgtgaat
      541 gtcatatttc aaatcgccgg agtgggaatc gtggtcgctt ttttacacac gatattggat
      601 cagatgggca agaaagaata tgctcagtgg gtgacgctgt taggttttat ctatatttta
      661 tttatggtcg ccacgattgt agatgaccta tttaaaaaga taaaagctgt gtttttattc
      721 caaggatagg ggggcttgca gattgacatt gttcaaattg taggtttagg gctgatcgcc
      781 accttccttt ctttaattgt aaaagaacaa aagccgactt ttgcgttttt aatcgtcgtt
      841 tttgccggat gtgccatttt tctttatttg gtagaccaaa tctacgacat tattcgaatg
      901 atagaaaaaa ttgcgattaa tgcaaatgtc aacatggtct atgttgaaac cattttaaag
      961 attatcggaa tcgcctatat tgctgaattc ggggcacagc tcacaaaaga tgccggtcaa
     1021 ggagccatcg cctcgaaaat agaattggcg gggaaaattt taatactcgt aatggctgtg
     1081 cctattttaa ccgtcattat cgaaacgatt ctcggactta taccttctat gtcataaccg
     1141 aaaggaggtg gtagattgaa gcgctttcaa tgggttttgc ttttggccgt gctgatcata
     1201 gcaggccgtg cagaaattgt acaagcagct ggtaatgcag aacaaacgga agaccatgct
     1261 gaaacagccg agcaattagc ggaaaggaca gcagcctcgc ttgaaacaga taagatcggg
     1321 gaattttgga atgacattat gacagaatac ggcggactgc tgccggaaag ccaaaaaggc
     1381 agcttaatgg agtttatcaa tggcgataaa tcattctcac cgcaagaatg gctgaaagct
     1441 ctcttttctt atttgtttca tgaagtgctt gccaacggaa agctgctggg cacattgatt
     1501 ttgctcacga ttttttgcgt cattctgcag cttttgcaaa atgcttttca gcaaagcacc
     1561 gtcagtaagg tcgcttactc aattgtgtac atggtgctga ttatccttgc gcttaatagc
     1621 tttcatgtgg caattaacta tgcaactgag gcgattcaga cgatgaccag ctttatcctg
     1681 gcgctcattc cgctcctctt ggcgcttttg gcttcctcag gcggagctgt atctgctgcc
     1741 ttctttcatc ctgttatcct cttcctgatg aacacgagcg gtctcttgat tcagaatatc
     1801 gtcatgccgc tgattttttt atcagcgatt ctgagcattg tcagcacgat gactgatcaa
     1861 tacaaagtaa cgcagctggc caacctgctc agaaatatcg ccatcggagc actggctgtt
     1921 tttcttacca tctttctcgg cgtcatctct gttcagggag cctcagctgc agtgacagac
     1981 ggcattacgc tcaggacggc taaatttata accggaaatt ttattcctgt gcttggccga
     2041 atgtttacag acgcaacaga tacagtaatc agcgcctctt tactgctgaa aaatacggta
     2101 gggattctcg gtgtcgctat tttgatctgt atcgcggcat ttccggcaat caaagtgctt
     2161 tccctcgctt ttatttataa gctggcagcc gcgattcttc agccgctagg aggcgggccc
     2221 gtcatcacct gcctcgacgt catcagcaaa agcgtcattt atatttttgc agctctcgcc
     2281 attgtgtctc tcatgttttt tttaagcctt actgtcataa tcacagccgg aaacctcacg
     2341 atgatgatga aatgaaggag gcaggcgaat gagtttttta acggaatggc ttaccaccat
     2401 cgtgttgttt atcctatttg caattgtgat tgatatgctg ctgccgagct ccagcatgca
     2461 aaagtacgca aaaatggtag tcagcctgct cttgattgtc gtcatgctta cgccgatttt
     2521 taaacttttc aagacagacc ccgaagtcat ctttgaatac ctcacaaaaa acgggcagtc
     2581 agagtctgcc gacataaaaa atcaaatcaa ttcaaaaaaa atagaaatac aagcttccca
     2641 gcgcgcatat attctagaag aaatggctgt ccaactaaaa aagaaagcgg aggagagatt
     2701 cagtcatgat gaatataaag taggccgcat caaactcacg gcaggagaaa aggtagattc
     2761 agaagaggat attaaaacaa tcagcgtgta tatggccccg tcttctgaaa aaacggtcca
     2821 aacggtcgcg ccggtccaca ttgatacaga tcatgcatac gtaacaaaag aagcagccga
     2881 acaaaaagaa gccaaacaga tacaaacgca gctcgcggac atttgggaaa tcggaagtga
     2941 gaaaattacg gttcatatgg aaggcgggga gagtgtcggc aatgaataaa aacggattat
     3001 ggaatgtatt gaaaaagcag tttcttccgg gacaaacgaa ggacggcgaa aagccgaagc
     3061 tgaccaaata tcattacttt ctattcgttt ttgttctcgg agtttccttt atgcttgtca
     3121 gccagctgtt ttcttcacct gagaaaacag aaaacgccaa aacgataacg gccgtatcat
     3181 cgcaacattc cgcagacagc aaagagaaaa cagctgaagt gtttaaagcc tcaaaatctg
     3241 ataaacctaa agactcgatc gatgactatg aaaaagaata cgaaaatcag ctgaaagaaa
     3301 tccttgaaac aatcattggt gtggacgatg tctcggttgt cgtgaatgta gatgcaacgt
     3361 cgctgaaagt atacgaaaaa aacaaatcaa acaaaaatac aaccaccgaa gaaactgaca
     3421 aagaaggcgg aacaagaagc gttacagacc aaacatcgga ggaagaaatc gtcatgatca
     3481 aaaacggcga taaagaaaca cctgtcgtcg tccaaacgaa aaaacctgat atacgcggtg
     3541 tactcgttgt tgctcaagga gtggacaacg ttcaaataaa acaaaccatt atcgaagcgg
     3601 tgacacgggt cctggatgtt ccaagccacc gggttgcggt tgcccctaaa aaaataaagg
     3661 aggattcata aatgcttaaa aaacaaaccg tttggctatt aacaatgctc agtcttgtcg
     3721 tggtgttaag cgtctactat atcatgtcgc cggaaagcaa aaacgccgtg cagatgcaaa
     3781 gtgaaaaaag tgcgtctgac agcggagagg tcgcaactga aaaagcgcct gccaagcaag
     3841 acacgaagga aaaaagcggt acagaaactg aaaaaggaaa agaagatgga acaaagggaa
     3901 cgaaagattc atcagcagac aaggaaacat ccgctgaagc cagtgaaaaa ggaactgttg
     3961 ttacggaaac agccgatgat gatctgttta caacgtaccg tcttgattta gaagatgcca
     4021 gaagcaaaga aagagaagag ctgaatgcca ttgtgtcaag cgatgatgca acagccaagg
     4081 agaaaagcga agcatacgat aaaatgacgg ctctcagtga agtggaagga acagaaaaac
     4141 agcttgaaac gctgattaaa acacaaggtt acgaggatgc gcttgttaat gctgaaggag
     4201 ataaaatcaa tattacagtc aaatcagaca aacactccaa atcgaaggcg acagccatta
     4261 tagaccttgt ggcaaaagaa atcaaaacaa tgaaagatgt cgctgtcaca tttgaaccat
     4321 ccaagtaaga aagaggaaaa agaagcccgc taaacaagcg ggctttttgc gttgctgtca
     4381 tattagagtt gaattcaaaa gtccgctcct gtaagatgaa catagtatgt acttttagta
     4441 gtaacctata aaaaagaaat ttcatacata ggagtgcgat tgaatgttaa atatcaaaga
     4501 aatccacgag ctgattaaag caattgacga gtctacaatt gacgaattcg tatatgaaaa
     4561 tgaaggtgta tccttaaaac tgaaaaaaca cgaagcaggc acggttcaag tcatgcagca
     4621 ggcaccggca gcacctgtac aagcacaggc tccgcaggca gttcagccgc aagcgcagca
     4681 agcagcggca cctgcccaag aagcaccaaa gcaagatgag aatctgcata aaatcacttc
     4741 accaatggta ggaacatttt atgcttcttc atcaccggaa gctggcccgt atgtaacagc
     4801 cggttcaaaa gtaaatgaaa acacagttgt ctgcattgta gaagcaatga agcttttcaa
     4861 cgaaatcgaa gcagaagtga aaggcgaaat cgttgaagta ttagtagaaa acggccagct
     4921 ggtcgaatac ggacaacctc tatttcttgt aaaagcggag taaggagact gaacatgatt
     4981 aaaaagctat tgatcgccaa cagaggagaa attgctgtca gaatcatcag agcctgcaga
     5041 gagctcggaa ttgagactgt cgctgtttat tcagaagctg ataaagatgc ccttcatgtt
     5101 caaatggccg atgaagcttt ttgtatcgga ccgaaagcat caaaagacag ctatttaaac
     5161 gttacaaata ttgtgagtgt tgcaaagctg actggcacgg acgccattca tccgggatac
     5221 ggatttttag ctgaaaatgc tgatttcgct gaattatgtg aagaagtgaa tgtcacgttt
     5281 gtcggcccga gcgctgacgc catttcaaaa atgggaacaa aagacgttgc gcgggaaacg
     5341 atgaaacagg ccggcgtgcc aatcgtaccg ggttcacagg gaattataga aaatgtggaa
     5401 gaagcggttt cgcttgctaa tgaaattggg tatcctgtaa ttataaaagc caccgcaggc
     5461 ggaggcggaa aaggaattag ggttgcccgc actgaagagg aactgattaa tggcattaag
     5521 attacacagc aggaagcggc aactgcattc ggaaatccag gtgtatacat cgaaaaatac
     5581 atagaagatt ttcgccacgt tgagatccaa gtgcttgctg ataactacgg aaatacgatc
     5641 catttgggcg aacgcgactg ctcgatccaa agacgcctgc aaaagctttt ggaagaatca
     5701 ccatctcctg cccttgattc agaaatcagg gagcaaatgg gagatgcagc ggtaaaggct
     5761 gcaaaagcgg ttggctatac aggtgctgga acagttgaat ttatctatga ctacaatgaa
     5821 cagcgctatt acttcatgga aatgaacacg agaattcagg tagagcaccc agtcacagaa
     5881 atggtgacgg gaactgacct gatcaaggaa caaatcaaag tggcatcagg aatggaactg
     5941 agcctcaagc aagaggatgt tgaatttgaa ggctgggcca tcgaatgccg aatcaacgca
     6001 gaaaacccaa gtaaaaattt catgccgtca cctggtgaaa ttaaaatgta cctgcctcct
     6061 ggcggtcttg gtgtccgtgt cgattcagct gcgtaccctg gctattccat cccaccgtac
     6121 tatgacagca tgattgcaaa ggtcatcaca tacggaaaaa cgagggatga agcgattgcc
     6181 cgcatgaagc gcgcattgag cgaattcgtc atcgaaggca ttgagacaac aatccctttc
     6241 catttaaaac tgcttgaaca cgaaacattt gtgagcggag agtttaatac gaaattttta
     6301 gaaacatatg atgtaatggg ctcataattt ttacggaggt gaattgaatg aaagacaaca
     6361 gcttgcttaa aatggatcac gaagatacgc atttgggtaa ggttgagatt gcaccggagg
     6421 tcattgaggt cattgccggc attgcagcat cagaagttga tggggttgcc gaaatgcgcg
     6481 gaaactttgc gacaggcgtc gtcgagcgct ttggcaaagt gaatcatggc aaaggtgtca
     6541 aagtcgacct ggcggatgac ggaattacga tcgatgtata ctgtgtcgtt acatttggcg
     6601 tttcgattcc gaaagttgca gcatccgttc aggaaaacat tcgtcaaacc ttattaaata
     6661 tgacgtctct ttcgattaac gagatcaata ttcacatcgt cggcattcaa tttgacacaa
     6721 aagcccaaga agtccaaatc gacgaagaaa tgtaaatggc ttaacacgaa accaagggga
     6781 gggcggccct ttggtttttt tacacgttac cctttatttc aaagcatgaa gaaagccggc
     6841 ttacatagcc gagtttcttc atgaacgtga aatccgaata atcatattaa ggtgtgtgaa
     6901 aatattcggt aatagggtaa aaaaccttga tttcaatatg cggatacgaa aaaaatatgt
     6961 tatgatctct ttgtggctta acgacaagcg gataaagagg atcaaaggag aaagaaaatg
     7021 aaaagaagaa cagcaagaga aaaagctttg caggcactat ttcaaattga tgtcagcgat
     7081 attgcagtga atgaagccat agaacacgca ctggatgaag aaaaaacaga tcctttcttt
     7141 gaacagcttg tacacggggt attggaacac caagaccagc tggatgaaat gatctccaag
     7201 catctggtga attggaagct cgatcggatt gccaatgttg accgtgcgat tttgcgcctg
     7261 gcagcatatg aaatggcata tgccgaagac attccggtga atgtctccat gaacgaagcg
     7321 attgagctgg caaaacggtt tggtgatgac aaagcgacaa agtttgtaaa cggggttctt
     7381 tctaacatta aatctgatat tgaacaatca taggaggaaa gaaaatgact gcaacaatca
     7441 tcgacggaaa agaaacggct agagaaaaac gcgaacaatt ggcaaaagag gtagaagagc
     7501 ttaaaaagca aggcgtcact cccggactgg cggttatttt gattggagat gatcctgctt
     7561 ctcactctta cgtgcgagga aagaaaaaag cggcagaaac aatgggaatg aatttcaagc
     7621 tcgatcaatt tgacagcagc ctcacagaag ctgaactgct ttccattatt gatcaatata
     7681 accaagaccc tgagtttcat ggcattctcg ttcagcttcc gctcccagac catatttctg
     7741 aaaaagcggt gatcgaacgt atctcccctg ataaagatgt agacggtttt catccgttaa
     7801 acgtagggaa aatgctgctt ggcgaagata cgtttcttcc ttgcacgcct catggaattg
     7861 ttgagctttt gaagaaaacc aatattgacc tttccggtaa agaggttgtt gtagtcggcc
     7921 gaagcaacat tgtcggcaaa cctgtcggcc agcttttatt aaatgaaaac gcgacggtta
     7981 cttactgtca ttcaagaaca gaaaatatta ctgaacatac gaaaaaagcg gacatcctgg
     8041 tggtggcagt cggcagagcc aacttcatca gtgcagacca gatcaaagag ggcgctgttg
     8101 tcattgacgt cggcgttaac cgtctggaaa acggaaagct ttgcggagac gttgaatttg
     8161 aaggggcaaa ggaaaaagcg tccttcatca cgccggttcc gggcggagta ggtccgatga
     8221 ccatcacgat gcttgcgcat aatactgtta aatctgcgaa acgtacgtta tcatagataa
     8281 ttggagatat tcacaggcga aatgtttgcc cgccttgaat aagagcacga tacccgcttc
     8341 ttcaggctcc taaagccagg gcgggttttc tttagttatg gtgcaggaat gcttaggaga
     8401 ggagttttta gacatgggtg aagcagcgta tgtgaccgtc tcagcgctga caaagtatat
     8461 aaaacgaaaa ttcgatgtag atcctcacct tgaaaatatt tggattaaag gcgaattgtc
     8521 gaatgtaaag atacacacac gagggcatat ttatttcact ttaaaagacg aaaacgcaag
     8581 aatgcagtcg gtgatgttcg cgagacaaag cgagcgtctg ccttttaaac ctgaaaacgg
     8641 aatgaaagtg ctggtaagag gcggaatttc cgtatatgaa ccgagcggaa actatcaatt
     8701 atatgccaaa gaaatgcagc ctgacggggt tggagcgctt tatttagcgt acgaagaatt
     8761 aaaaaagaag cttgccggag aaggtttatt tgacgaccgc tacaaaaaac aaatccccgc
     8821 atttccagcc acaatcgggg ttgtgacatc tccaacgggt gccgctgtca gagacgttat
     8881 tacaactcta aaaagaagat atccccttgt aaaagttatt gttcttccag cgctcgtaca
     8941 aggtgaaaat gcgagcagat ccatcgttac gcgcattgaa gaggcaaatg aaaaagagat
     9001 ttgcgacgta ttaattgtcg ggagaggcgg cggttcgata gaagaactgt gggcattcaa
     9061 tgaagaaatt gtagcacgcg ccatctttgc ttccaatatt ccgattatat cggcagtcgg
     9121 acatgagacg gattttacga tcagtgattt tgtcgccgat atcagagctg cgacgccgac
     9181 aggagcagct gagattgctg tgcctcatac cactgattta atcgaacgga caaaaacagc
     9241 ggaagtcaga atgacaagag caatgcagca gcatctcggc cagaaaaaag aacggataca
     9301 aacgctgcaa tcgtcctatg cctttcgttt tccaaagcgt ttgtatgcgc aaaaagagca
     9361 gcagtttgac ctcgcgtacc agcagtttca agcacagctg accgctcttt tagatcggaa
     9421 aagcagacag ctggagcgtg aaacgtacag attagaggca ctgcatcctc atgaacagct
     9481 gaaacaagca agaacacgat atcaggaaca aacaaatcag ctgagaaaaa atatgaatat
     9541 ccaaatgaag cagctgcatt cccaatttca aaccgttctt ggcaagctga atgcactaag
     9601 tcctcttcaa gtgatggaaa gaggatacag cttggcttat aaagaagata aactcattaa
     9661 aagtgtcagt caaatagaag agcaggaccg gcttgaagtc aagctgaagg atggcgtgct
     9721 gacctgtgaa gtattagaaa agagagggga agaaaaatga cagacgtgaa aaaaaatgaa
     9781 aacatgacat ttgaagaagc gatgaaaggg cttgagagca ttgtatcaaa gcttgaagag
     9841 ggagatgtgc ctctagagca agccattaac tatttccaag aaggcatggc tctgtcaaaa
     9901 atgtgccatg aaaagctgca aaaagtcgaa aagcaaatgg acttcatttt aaaagaagac
     9961 ggcgaactgg cacctttcag tgttcaggag gaagacgaag gtgacaaata aattaacgag
    10021 ctttctggcg gaccggaaaa aaacaattga aaatcagctt tctgtctata cagaaaagct
    10081 tgatatgccg gactcattaa agaagtctat gctgtattct ctacaggccg gcggaaagcg
    10141 gttgcggcct ctgattgtac tggctgtttt aaacgcatat ggaaaaagcg aaaaagacgg
    10201 cattccggtg ggctgtgctg tcgaaatgat tcacacgtat tcgttaattc atgatgatct
    10261 tccatgcatg gatgatgacg atttgcgccg tgggaagccg acaaaccata aagtgtttgg
    10321 tgaagcgacg gcagtattag cgggtgacgg gctgctcaca gaaagcttta agctgattac
    10381 ctcccacgtg tcagacgagg tgtcagcaga aaagcgcctg cggcttgtga atgaactgat
    10441 ttcagcggca ggcaccgaag gcatggtcgg tgggcaagta gctgatatgg aagcggaaaa
    10501 ccgacaagtc acgcttgaag agctcgaatc cattcatgaa cggaaaactg ccaagctcct
    10561 tggcttttgt gtaatcgccg gtgctatttt ggctgatgcg cctgaggaag acattgaaac
    10621 actgcgtacc ttcagcagcc acattggaat cggatttcaa atcagagacg atattttaga
    10681 tttagaaggc agtgaagaga aaatcggcaa acgtgtcggc tcggatacca caaatgacaa
    10741 atcgacatac ccgtcgcttc tttcattgga aggggccaaa cataaattgg atgttcatat
    10801 aaaagaggcg aagcgattga tcggcggact ctctcttcaa aaagaccttt taaatgagct
    10861 ttgtgattta attgcggcga gagatcacta aaacgatcct aatttgaagc ggctgcacga
    10921 gatatggtaa aatgtaagca gtttatatga aaaatgaaaa ggaaaagcgc gtttgtcttt
    10981 ttttatgtct gagattattg tcagctcggc atgcaaaaga catgtatcat tgcagaaatt
    11041 catgctgaaa gtgagttgat ccgctttgga tcttttatca atacaggacc cgtcgttttt
    11101 aaaaaacatg tccattgatg aattagagaa attaagtgat gaaatccgtc agtttttaat
    11161 tacaagttta tccgcttccg gcggccacat cggcccaaac ttaggtgtcg tagagcttac
    11221 tattgctttg cataaggaat ttaacagccc gaaagacaaa tttttatggg atgtaggcca
    11281 tcaatcgtat gtccataagc tgctgacagg acgcggaaaa gaatttgcga cgcttcgcca
    11341 gtacaaaggg ctttgcggat ttccaaagcg gagtgaaagc gagcacgatg tttgggaaac
    11401 cgggcacagc tcgacttctc tgtcaggcgc gatgggaatg gcagctgccc gtgatattaa
    11461 aggaacggat gaatatatta ttccgatcat tggtgacggc gcgctgaccg gcggaatggc
    11521 gctcgaagcc cttaaccaca tcggcgacga gaaaaaagac atgattgtca tccttaatga
    11581 taatgaaatg agtattgcac cgaatgtcgg tgccattcac tctatgctcg gacggctccg
    11641 tactgcgggg aaataccagt gggtcaaaga tgagcttgaa tacttattta aaaagattcc
    11701 ggcagttggg ggcaagcttg ccgccacggc ggaacgagtc aaagacagcc tgaaatacat
    11761 gctcgtctcc ggaatgtttt tcgaggagct cggttttacg tatttgggcc cggtggacgg
    11821 acattcttat catgagctga ttgagaatct tcaatacgcc aaaaaaacga aaggccctgt
    11881 tcttctgcat gtcatcacga aaaaagggaa ggggtacaaa ccggctgaga ccgatacgat
    11941 tgggacatgg catggtaccg gaccatataa aattaatacc ggtgactttg taaagccgaa
    12001 agccgcagct ccttcgtgga gcggtcttgt cagcggaact gtgcagcgaa tggcgcgcga
    12061 ggacggacgc attgtagcca ttacgccggc tatgcctgtc ggttcaaagc ttgaaggttt
    12121 cgcaaaggaa ttccctgacc ggatgttcga cgtaggaatc gcagaacagc atgccgcaac
    12181 gatggcggca gctatggcaa tgcagggtat gaagccgttt ttggcgattt actcaacctt
    12241 cctgcaaagg gcatatgacc aagttgtcca tgacatctgc cgccaaaacg ccaatgtgtt
    12301 tattggaatt gaccgtgcag gactcgttgg cgctgatgga gagacacatc aaggcgtgtt
    12361 tgatattgcg tttatgcgcc acattccaaa catggtctta atgatgccga aagacgaaaa
    12421 tgaaggccag cacatggttc atacagcact tagctatgac gaaggcccga tagcgatgcg
    12481 ttttccgcgc ggaaacggac tcggcgtaaa aatggatgaa cagttgaaaa cgattccgat
    12541 cggtacgtgg gaggtgctgc gtccggggaa cgatgctgtc atcttaacat tcggcacaac
    12601 aatcgaaatg gcgattgaag cagccgaaga gctgcagaaa gaaggccttt ccgtgcgcgt
    12661 tgtgaatgcg cgttttatta agccgattga tgaaaagatg atgaagagta tcctaaaaga
    12721 aggcttgcca attttaacaa ttgaagaagc ggtcttagaa ggcggtttcg gaagctcgat
    12781 tttagaattc gctcatgatc aaggtgaata tcatactccg atcgacagaa tgggtatacc
    12841 tgatcggttt attgaacacg gaagcgtaac agcgcttctt gaggaaattg gactgacaaa
    12901 acagcaggtg gcaaatcgta ttagattact gatgccgcca aagacacaca aaggaattgg
    12961 atcatgacgt caaagaaaga acgattagat gtattattag tggaaagagg gctggcggaa
    13021 acgcgtgaaa aagccaaaag agccattatg gcggggatcg tctattcaaa cgaaaaccgc
    13081 ttggacaagc ctggagaaaa aattgaccgc gaccttccgt taactgtcaa aggaaacccg
    13141 ctgaggtatg tgagcagggg cggcttaaag ctcgaaaaag cgttgaagga atttcccgtc
    13201 tctgtcaaag ataaaattat gattgatatt ggctcctcca ccggcggttt tacggactgc
    13261 gctttgcaaa atggagctaa acagtcatac gctgtggatg taggctataa tcagcttgca
    13321 tggaagctta gacaggatga acgggtcgtc gtgatggaac ggacgaactt tcgttatgca
    13381 acaccggcag actttacaaa gggcatgccg gagtttgcca caattgatgt gtcctttatt
    13441 tcactgcggc tcatcctgcc tgtcctaagg actttactcg taccgggcag cgactgcatg
    13501 gctctagtta agcctcagtt tgaagcggga cgggaatccg tcggcaaaaa agggattgtc
    13561 agagatccta aagtgcatgc tgatgtgctc aagcgaatga tcagtttttc tgccgctgaa
    13621 ggctatatct gtaaaggctt gtcattttct ccaatcacgg gaggagacgg aaatattgag
    13681 tttctccttc atttgcattg gccgggagag ggacaggaag gtcaggagct gccggaagaa
    13741 gagatcatgc gcgttgtaga agaagcacat aagacgttaa aagaaaaaaa agcagatgta
    13801 ccggaataat agggcgctat tattcctttt ttctgcattc atgtacaatg tgcagagaat
    13861 catataacat aaaagaacag ataagcttgg aaatagaggt gcttacatga acaaaggcca
    13921 gaggcatatt aaaatcagag agatcattac aagcaatgaa atcgaaacgc aggatgaatt
    13981 ggtcgacatg ctaaagcagg atggatacaa agtaacgcaa gccacggtat cacgggatat
    14041 taaagaactt caccttgtaa aagtgcctac aaataacggt tcttacaaat acagtcttcc
    14101 ggcggaccag cgtttcaatc cgctgtctaa gctaaagcgg gccttgatgg acgcatttgt
    14161 gaaaatagac tctgcaagcc atatgatcgt actgaaaacg atgccgggca atgctcaggc
    14221 aatcggggcg ctgatggaca atttggactg ggatgaaatt atggggacca tttgcggaga
    14281 tgacacgatt ttaattattt gccggactcc tgaagataca gacggtgtaa aaaacagact
    14341 gcttgaactg ctgtaacaga atctaacaaa gataagaggt gtaatgctgt ttgttagctg
    14401 aactatcgat taaaaacttt gccattattg aggaactgac ggtttctttt gaacgcgggc
    14461 ttacggtttt aacaggagaa accggagccg gcaaatccat tatcatagat gccatttctc
    14521 ttttagtcgg aggccgcgga tcatctgaat ttgttagata tggggaagca aaagccgaac
    14581 ttgaagggct gtttctgttg gagagcggcc atcctgtttt aggcgtatgc gctgagcagg
    14641 gaatcgacgt ttcagacgaa atgatcgtca tgagaaggga tatcagcacg agcgggaaaa
    14701 gcgtttgccg tgtcaatggc aagcttgtca cgattgcctc gctaagagag atcggcaggc
    14761 ttttattaga tattcacggg cagcacgata accagctgtt aatggaagac gaaaatcatc
    14821 tccagctttt ggacaagttt gccggggccg aagtggaaag cgcgctcaaa acgtatcagg
    14881 aagggtacca gcggtatatg aagctgctca aaaagcttaa gcagctttct gaaagcgaac
    14941 aggaaatggc ccatcgtctt gatcttattc aatttcagct cgaagaaatc gaatcggcaa
    15001 agcttgagct taacgaagat gaacagctcc aagaagagcg ccaggaaatt tcaaactttg
    15061 agaagatata tgaatcgctg caaaatgcat ataacgcgct tcgcagtgag cagggcggat
    15121 tggactgggt cggaatggct tcagcgcagc ttgaagatat ctctgatatt aacgaaccgc
    15181 tgaaaaaact gtctgaaagt gtttcgaact cctactattt gcttgaggat gccacatttc
    15241 agatgagaaa tatgctggat gagcttgaat ttgatccgga acgcctgaac tatattgaga
    15301 cacgacttaa tgaaatcaaa cagctgaaac gaaaatacgg tgccactgtt gaagacattt
    15361 tggaatatgc ttctaaaatt gaagaagaga ttgaccaaat tgaaaacagg gacagccacc
    15421 ttcaaagctt gaaaaaggag cttgactccg tcggcaaaga tgtcgcagtg gaagcggcaa
    15481 atgtgtcaca aatccgaaaa acatgggcga aaaagctggc tgatgagatt catcgggaat
    15541 taaaaagcct gtacatggaa aaatcaactt ttgatacgga atttaaggtc agaacagcgt
    15601 cacgcaatga agaggcgccg cttgtaaacg gccagcccgt tcagctgact gaacaaggga
    15661 ttgacctggt gaagttttta atttcaacca atacaggcga gccgctgaaa tccctttcga
    15721 aagtcgcttc aggtggagag ctgtcacggg tgatgcttgc cataaaaagc attttctcct
    15781 cacaacagga tgtgacatcg atcatttttg acgaggttga taccggtgta agcggcaggg
    15841 tcgcacaggc aatcgctgag aagatccata aggtgtcaat aggttcacaa gtgctgtgca
    15901 ttacacacct gcctcaggtg gctgccatgg ccgatacgca tctttatatt gcgaaggagt
    15961 taaaagacgg cagaacgacg acacgtgtca agccgctctc taagcaggaa aaggtagcgg
    16021 aaatcgggcg catgattgca ggtgtcgaag taaccgactt aacgaaacgc catgcgaaag
    16081 aacttttaaa acaagcggat caagtcaaaa caactgggta agctgcgcga gaagcgcagc
    16141 ttattttttt cgtgtacatc cattcgttca tcagtatatc caatgttttt cttcatatga
    16201 cagttataaa taagccgtca gaaggcaaaa ttaaatgatg tagcagcaag tcataaagaa
    16261 ggtgtgggat aggagcgagg agagtgaagt agtgaatgcc cgataacatc agaaaagcag
    16321 taggtttaat tctccttgtt tcgttattaa gtgtaggttt atgcaaaccg ctaaaagaat
    16381 atttactgat tccaacgcaa atgagagtat ttgaaaccca aacacaagcg attgaaacga
    16441 gtttatcggt aaacgctcag ccatcagaat cctcagaagc gtttacagta aagaaagatc
    16501 cgcatgaaat caaggtgacg ggcaaaaaat caggtgagtc agaattggta tacgatcttg
    16561 ccggatttcc aataaaaaaa acaaaagtgc atgttcttcc tgatttaaag gttatacctg
    16621 gcggacaatc aatcggtgta aaacttcatt ccgtcggtgt tcttgtcgtc ggatttcatc
    16681 aaatcaatac aagtgaaggc aaaaaatctc cgggagaaac ggctggaatt gaagcgggcg
    16741 acatcattat tgagatgaat ggacagaaaa ttgaaaaaat gaatgatgta gccccattta
    16801 ttcaaaaggc tgggaaaact ggtgaatctt tagatttact gatcaaacgt gataaacaga
    16861 aaatcaaaac gaagctgatc ccagaaaagg atgaaggaga aggcaaatac agaatcgggt
    16921 tatatatcag agattctgct gccggcatcg gcactatgac cttttatgaa ccgaaaacaa
    16981 aaaaatacgg agcacttggc cacgtgattt ccgatatgga cacaaagaaa ccaattgtag
    17041 tggagaatgg agaaatcgtt aaatccactg taacatcaat tgaaaaaggg acaggcggta
    17101 atccgggaga aaaactggcg cgattttcct cagaacgcaa aacgatcggg gatattaaca
    17161 gaaacagccc gtttgggatt ttcggcacac tgcatcagcc gattcaaaac aacatatcag
    17221 atcaagcatt gccggttgcg ttttctaccg aagtcaaaaa agggccggct gaaattttaa
    17281 cggttattga tgatgacaaa gtagaaaaat tcgatattga aatcgtcagc acaacgccgc
    17341 aaaaattccc tgcgacaaaa ggaatggtgt tgaaaattac cgatccaagg ctgttgaaag
    17401 aaacaggagg catcgtacag gggatgagcg gaagcccgat tattcaaaat ggaaaagtga
    17461 tcggtgctgt cacccatgta tttgtaaatg acccgacaag cggctacggt gttcatattg
    17521 aatggatgct gtcagaagca ggaatcgata tttatggaaa agaaaaagca agttgactgc
    17581 cggagtttcc ggcagttttt ttattttgat ccctcttcac ttctcagaat acatacggta
    17641 aaatatacaa aagaagattt ttcgacaaat tcacgtttcc ttgtttgtca aatttcattt
    17701 ttagtcgaaa aacagagaaa aacatagaat aacaaagata tgccactaat attggtgatt
    17761 atgatttttt tagagggtat atagcggttt tgtcgaatgt aaacatgtag caagggtgaa
    17821 tcctgttaac tacatttggg gaggaagaaa cgtggagaaa attaaagttt gtgttgctga
    17881 tgataatcga gagctggtaa gcctgttaag tgaatatata gaaggacagg aagacatgga
    17941 agtgatcggc gttgcttata acggacagga atgcctgtcg ctgtttaaag aaaaagatcc
    18001 cgatgtgctc gtattagata ttattatgcc gcatttagac ggacttgcgg ttttagagag
    18061 gctgagggaa tcagatctga aaaaacagcc gaatgtcatt atgctgacag cctttggaca
    18121 ggaagatgtc acgaaaaagg ccgtcgattt aggcgcgtcc tactttattc tcaaaccgtt
    18181 tgatatggaa aaccttgtcg gccatatccg ccaggtcagc ggaaatgcca gcagtgtgac
    18241 gcatcgtgcg ccatcatcgc aaagcagtat tatacgcagc agccagcctg aaccaaagaa
    18301 gaaaaatctc gacgcgagca tcacaagcat tatccatgaa atcggcgtcc cagcccatat
    18361 taaaggctat ctctatctgc gcgaagcaat ctcaatggta tacaatgaca tcgaattgct
    18421 cggcagcatt acaaaagtcc tctatccgga catcgccaaa aaatttaaca caaccgcaag
    18481 ccgtgtagaa agagcgatcc gccatgcaat tgaagtggca tggagcagag gaaacattga
    18541 ttccatttcc tcgttgtttg gttatactgt cagcatgaca aaagctaaac cgacaaattc
    18601 ggaattcatt gcaatggttg cggataagct gagattagaa cataaggctt cttaaacatg
    18661 agcttattaa gtggtcatta aatcaaacgt cttttattta ttagtttgcg ctgataaata
    18721 ggaggcgttt tgttttgggg acatttgtag tatgggagaa gaatattaag tatccgcata
    18781 tagtaaagga taggtttgaa aagtaaggaa agcaaatggc ggtattacct gcactcttgg
    18841 tccattcata catcttatag gatcacgaag catgatcgac cctaaatatg tccgttataa
    18901 aatgaaacct ttctcctgca aaatcgtaag taaggcgtat tcatgtaaaa aggagacgta
    18961 cgaatgaaaa agaaaaaagc aagaaagcgt gaggggtttt tcctggactt tcttttcgaa
    19021 gttggtgggg agctctttct tttgctgttt agatgtgtac acaaactatt tatataaagg
    19081 gaaaaagact gccgaatcgt ttcggcagtc ttttgcacat taatctttat aaggcaccca
    19141 gcctggcgtg ttcacaattg cttgccatag cggttcaggc aaatgatatt tatctttatc
    19201 tgtgcctttg atcactgttt cgatttgctt ttcacggcct tcttttactt ttaccgtcca
    19261 gtcagggtca actagaattt cgcgtcccat agcgactagc ggaataccgt tttcgatgac
    19321 ggcaagcgcg tcatcagcgg aatggatgga accgacggcg atcagcggca ctttgtttcc
    19381 gacacgttca ttcaataagt ccatgcgtgt gcgagtcgga tctgcaccgc ggcgcgcttt
    19441 tgagttcacg tccatcagtg agatatgaag atagtccaat tctttatccc ctaaagcatc
    19501 aacaagcgta taagtttcag tcattgtcaa tcccggtgtc tcaggttctt ccggagacag
    19561 acggtagccg actaagaacg cacccttcgc atgttctgaa gcggcttttt tcacttcatc
    19621 gacaatagcg agcgggaagg ctaatcgttt ttcatcgctt cctccccagc gatccgtgcg
    19681 ctggttggtt ttcggagaat aaaactgctg aattaagtag ccgtttgcac cgtgaatttc
    19741 gacaccgtca aagcccgctt caatggcacg tcttgtcgct tctccaaacg ccttcacaat
    19801 gttttccact tcttcttctt ttaatgcgcg agcaatttgt ttgccgttat caaacacgtc
    19861 acttggcccc acaacatctt gttgaggaac aagctcagac gggcactcaa taccgccgtg
    19921 atgaatttgt acaacagctt tagcgccttg tgcctgaatg gcttgtgcta acttttttaa
    19981 acctggaatg ttggaatcgt catggatggc cggctgcccg gggaatgctt ttccgtccgg
    20041 tgtaacattt gcgcaggctg taatcaccat tcccatctct tttgaacggg ggatgatgta
    20101 gtcgagctcc gcttcagata ttgtaccgtc ttcattagaa gcgtaatgag tcattggtgc
    20161 tactgcgatc cggttgtcga ttgtgacgcc gcttttaaac gtaaatggtt caaaaagtgg
    20221 cttatactta ggattcattt gatcatcttc tttcgtttgg attcgcacat attctagcct
    20281 atatgtaaaa attaatgcaa ttgatctgct ttaccgactg aatatcttga gtgcagagtg
    20341 atgttttcgc cgctcttttt cggggccttt gtagccgccg ctgatttggt ggccgatgga
    20401 gcatgtgatg acagctgccg ccagcagcag aacgaatttt ttcatggctt taacttcttt
    20461 caataaagta aatatccttt aaaaggttac gcttggctga cccacccgtc aaacgatttg
    20521 ctcaccctat tctcaaattt tttaaaatga ataaaaagtt gcttctttcc gctaattttt
    20581 tctaattgac gcctcaatta gagccatcct catagacaaa tctgctcgtt atctttctaa
    20641 caacaggaaa tgatcgggtc gtatagccct tttgaaaatc atggaacttg ctcgcctgca
    20701 ttcgcgttgt ctttacaaat tcgccattct ggtcaaagat aaaagccaaa catcaggaag
    20761 aggtggtcat gtgaaacaaa cggttctttt gctgtttact gcgctctttc tttcggggtg
    20821 cagtgttgca agtgcggatg actcagtgcc aaggtttacc gaagagggaa aatacattgg
    20881 ctcggctgat c
//
