LOCUS       NZ_QRFZ01000012        21612 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis subsp. subtilis strain EA-CB0575 BS575_12, whole
            genome shotgun sequence.
ACCESSION   NZ_QRFZ01000012
VERSION     NZ_QRFZ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis subsp. subtilis
  ORGANISM  Bacillus subtilis subsp. subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 694111)
  AUTHORS   Franco-Sierra,N.D., Posada,L.F., Santa-Maria,G., Romero-Tabarez,M.,
            Villegas-Escobar,V. and Alvarez,J.C.
  TITLE     Bacillus subtilis EA-CB0575 genome reveals clues for plant growth
            promotion and potential for sustainable agriculture
  JOURNAL   Funct Integr Genomics 20 (4), 575-589 (2020)
   PUBMED   32198678
REFERENCE   2  (bases 1 to 694111)
  AUTHORS   Franco-Sierra,N.D., Santa-Maria,G. and Alvarez,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) Process Engineering, Universidad EAFIT, Cra
            49 7 sur 50, Medellin, Antioquia 050022, Colombia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-MAR-2015
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011800745.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:42:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,261
            CDSs (total)                      :: 4,164
            Genes (coding)                    :: 4,041
            CDSs (with protein)               :: 4,041
            Genes (RNA)                       :: 97
            rRNAs                             :: 4, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 62 of 123
            Pseudo Genes (incomplete)         :: 65 of 123
            Pseudo Genes (internal stop)      :: 19 of 123
            Pseudo Genes (multiple problems)  :: 21 of 123
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:02:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 659840
            Orig. end                         :: 681452
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QRFZ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="3"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(116..130)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(208..3894)
                     /gene="narG"
                     /locus_tag="DXT72_RS18975"
     CDS             complement(208..3894)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="DXT72_RS18975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_167408502.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPGKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQKKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPGQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNNWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3960..3975)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3984..3997)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3984..3998
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4085..4561)
                     /gene="arfM"
                     /locus_tag="DXT72_RS18980"
     CDS             complement(4085..4561)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="DXT72_RS18980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4619..4634)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4705..5424
                     /gene="ywiC"
                     /locus_tag="DXT72_RS18985"
     CDS             4705..5424
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="DXT72_RS18985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YwiC-like family protein"
                     /protein_id="WP_014481214.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(5456..6172)
                     /gene="fnr"
                     /locus_tag="DXT72_RS18990"
     CDS             complement(5456..6172)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="DXT72_RS18990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_014481215.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="DXT72_RS18995"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="DXT72_RS18995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrate transporter NarK"
                     /protein_id="WP_015250995.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGVGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="DXT72_RS19000"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="DXT72_RS19000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_015250994.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELDKLRKDLENFRVPFDVWYSETSLYQNGKIDTALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="DXT72_RS19005"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="DXT72_RS19005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_167408503.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLFYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="DXT72_RS19010"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="DXT72_RS19010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 1.5e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="DXT72_RS19010_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="DXT72_RS19010_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="DXT72_RS19015"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="DXT72_RS19015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="DXT72_RS19020"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="DXT72_RS19020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_024573031.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 8.5e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.6e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2e-45, bitscore:
                     150.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 5.8e-07, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.8e-22, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.7e-11, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.7e-10, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DXT72_RS19020_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="DXT72_RS19020"
                     /locus_tag="DXT72_RS19020"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="DXT72_RS19025"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="DXT72_RS19025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="DXT72_RS19030"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="DXT72_RS19030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="DXT72_RS19035"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="DXT72_RS19035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_019712818.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATLPLCAVHILWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIS
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="DXT72_RS19040"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="DXT72_RS19040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_167408517.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 8.9e-06,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSYTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="DXT72_RS19045"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="DXT72_RS19045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pitrilysin family protein"
                     /protein_id="WP_167408504.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.3e-14, bitscore:
                     49.0, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLKQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDINDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLSIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16926
                     /gene="albG"
                     /locus_tag="DXT72_RS19050"
     CDS             16237..16926
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="DXT72_RS19050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_167408505.1"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVFIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTA"
     gene            complement(16939..18315)
                     /gene="ywhL"
                     /locus_tag="DXT72_RS19055"
     CDS             complement(16939..18315)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="DXT72_RS19055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YncE family protein"
                     /protein_id="WP_167408506.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEGIGVRYAVRVQGTITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSAVPTNLGVTFDKAFTYILHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLMTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18282..18299
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18354..19709)
                     /gene="ywhK"
                     /locus_tag="DXT72_RS19060"
     CDS             complement(18354..19709)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="DXT72_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YncE family protein"
                     /protein_id="WP_015250986.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     gene            complement(19706..19936)
                     /locus_tag="DXT72_RS21580"
                     /pseudo=""
     CDS             complement(19706..19936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="DXT72_RS21580"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQ"
     misc_feature    19890..19906
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19939..21084
                     /gene="rapF"
                     /locus_tag="DXT72_RS19070"
     CDS             19939..21084
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="DXT72_RS19070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator aspartate phosphatase RapF"
                     /protein_id="WP_014481226.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     gene            21068..21187
                     /gene="phrF"
                     /locus_tag="DXT72_RS19075"
     CDS             21068..21187
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="DXT72_RS19075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_009968329.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     misc_feature    21589..21602
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
ORIGIN
        1 agctttcctt ttttcaatgt ccagccgcct ttatatttgt cctggtcctc ccattgcttc
       61 gggtagccga tgcccggctt tgtttctaca ttattgaagt acatatattc cgcaccggaa
      121 cggtttgtcc acgtgttttt gcaggtgacg ctgcacgtgt ggcagccgat gcatttatcc
      181 aagttcatga ccataccgat ttgcgcttta atcttcaagc caatcgacct ccttcagctt
      241 gcggatgacg acgttcaggt cgcgctgatt ccccgttggg ccgtaatagt taaagccgta
      301 gctgagctgg gcgtagcccc cgatcatctg tgtcggcttg acgtgaatcc ttgtcgggct
      361 gttatgggtg cctccgcggt tatttgtcag tttcgtgccg ggcacgttga tgtggcggtc
      421 ctgggcatgg tgcataaacg ccattccttt aggaatccga tgagacaaaa cggctctcgc
      481 gacgactacg ccatttcggt tgaagcattc aatccaattg ttgtctttga tatccgtatc
      541 ctctgcatca tctttattca tccatacggt cggcccgccg cggaacagcg tcagcatcgg
      601 cagggaatca aaatacatgc tgtggacgga ccatttgtta tgcggcgtca aataattgag
      661 gacgatttct tttccctctt gaccaggccg cttgctcaga aacgggcgat gctggaggat
      721 cggtttgaat gtcgccatcg tttcaccgaa ttccatcatc agttcatgat cgacataata
      781 ggattgtctg cctgtcagcg tccgccacgg gattaatttt tcaacattcg tcgtaaacgg
      841 cgaatacctg cgccctcctt tttcagagcc ggaaaacgct ggagacgtga tcaccgtttt
      901 cggctgggct gtaatttgtt cgaacgtaaa gcattcttcc tcgcgttctt ccgccaggtc
      961 tttcagcttc aggttcgtga tgttttcaag tgattcccat gcttttactg cgacctttcc
     1021 attcgaagtg gatgataggg ttaaaatcgc ttctgctgcc tgctttgctt cacttatatt
     1081 tggacatccc tttgcgacac tgtccgaggt gatttctccc aatctctgtt tgagtgattc
     1141 atattcatcg gctattgacc agctcatccc ttttgttccg ctcggcttta aagcaacgtt
     1201 cggaccaagt gcagtcattt tatgaaaaat gtgtttgtaa tcccgttcaa cgacttggat
     1261 gttcggcatc gtttttcccg gaatggcttc acattcgcct ttgctccagt cattgatttt
     1321 gccgaatggc tgggccaatt cctgcatggt gtcgtggagg agcggcgtcg caaccacttc
     1381 tttcacgggc tccatatcga cttcttctgc cagatcggaa acggcttttg acagcgcctt
     1441 gaaaatatcc cagtctgact tcgattccca cggagccgag atcgcaggag caaatggatg
     1501 aatgaacgga tgcatatctg tgctgctgag atcgtgtttt tcataccatg tcgccgccgg
     1561 cagcacgata tcggaataca gcgccgtacc ggccattcgg aagtcgagat tgattaacaa
     1621 gtcgagcttt ccttccggcg cctgctcccg ccatttgatt tcttcagggc ggatgctgtc
     1681 gctgtcgtca ttcatcaagc cgttcgtcgt ccccagcaaa tgcttgagaa aatattcatg
     1741 cccttttcct gagcttgaga tcagatttgc ccgccatacg aagagatttc ttgggaaatt
     1801 cacttcattg tcgggatctt caatcgcaaa tttcagtttt ttcttttgga gctgtgaggc
     1861 cacgtacgca cctacgtctt cgggtgttgc tgcccctgct ttttcagctt ctttatacag
     1921 atcgatgcca ttttgattga aagtcgggta agacggaagc caccccagcc gtgccgccag
     1981 cacattgtaa tcagcgtggt gcttgtagcg ggatgacgca gcaatcggcg atgccaaatc
     2041 actgatcggc tggtcctcat aacgccactg atctgtcgca aagtagaaaa atgaggtgcc
     2101 gttttgcagc ttgggcacgc cctcccagtc ctttgcagtt gcaatcgtct gccacccttc
     2161 agcaggtcgg agcttttcct gccccacgta atgggcccag cctccgccgt ttacgccttg
     2221 ggcgcctaca agtaaaacaa gatttaacac cgctcggtag atcgtgtcgg agttgaacca
     2281 gtggttaatg ccggccccta cgataatcat ggaccggccg tctgtatcga tcgcattttg
     2341 ggcaaactct ctggcaatct taacgacagc ttcttttttg attcctgtca tttgttcctg
     2401 ccaggcaggc gtaaacggct caggatcatc ataggagaca gccgatcgtt cgccgatacc
     2461 ccggttcacg ccgtagttag ccagtatcaa gtcaaacacg gtcgtgatgt acgtttcttc
     2521 accgttcagg ttcatttttt taataggaag atcccgctcg agcactttgt ttccgtcatt
     2581 tgaaaaatac gggatgcgca ccgtgccgat ttcgtcctct attcccagca cagagagacg
     2641 gggttcaatc ggttccccgg tttcttcatc aatcatgtgc aggttccatt tctgctgccc
     2701 gtcccagcgc gagcccattg tcccttgggg tatggcaaat gaacttgtct gttcatccca
     2761 aaccgcaggc ttccactgat catgctttgt cttccgcccg atgtccttcg catgcagaaa
     2821 ccgtcccgct gtgtatacgc cattttcttt tgacagagtg acgagaaatg gaaaatcagt
     2881 gtattgcttc gcgtactcaa taaaacgttc agtttcttgg ttcacgtaaa attcctgcag
     2941 aataacgtga cccatcgcca tcgcaagcgc cccgtcagtc ccttggcgaa tactcagcca
     3001 gtcatccgcg aactttgagg attccgcaaa atctggactg atcgaaatga ccttagcgcc
     3061 tttatagcgg gcctccgcca aaaaatgcgc gtcaggcgtt ctcgttaacg gaacgttgga
     3121 gccccatgtg ataatatagc cggaattgta ccaatcactg ctttccggaa cgtccgtctg
     3181 gtcaccccaa atttgcgggg atgctggagg aagatccgca taccagtcat aaaaactgag
     3241 catagggcct ccgattaacg acataaaccg ggagcctgat gcgtggctga tcatggacat
     3301 ggccggaatc ggagaaaaac cgacgtttcg gtcaggcccg tatttcatca ctgtatacag
     3361 cagagaggct gaaatcagct tcagcacctc cggccattca gcgcgcacaa aaccgccttt
     3421 ccctctcgcc tgtttatagg acttcgcttt tccagggttt tcgacgatcg atttccaggc
     3481 ttccaatgga ttttgatgcg tctgcaatgc ctcccgccac aaattgatca gcacaccgcg
     3541 cacgtatgga tatttcacac ggagcgggct gtagatatac catgaaaaac tggccccccg
     3601 cgggcagcct ctcggttcaa aatcaggcat atccgggcct gttgatggat aattcaaatt
     3661 ttgcccttcc cacgtgacaa ttccgttttt cacataaata ttccagctgc aagaccctgt
     3721 acagttgacg ccgtgggtgg agcgaacgac tttgtcgtac tgccatctgt ttctgtatac
     3781 attctcccaa tcgcgatcct cgcgggtagt ttggctatgt ttatttgaat ggtgttcgat
     3841 aggagagaaa taattcaatc tcctaaacaa cggactcatt ttctttttct tcatgagagt
     3901 tcactccttc cgagtcaggt gatgctaagt tcactataaa cagagacagc gtgtttcctt
     3961 gtgaactatg tcacacactc cgcttttttc acaaaatgtt cacacaaagg agaaggaagg
     4021 ctgcgttcag gcagaacgct tgggtcatta gccgcctttc aaagatcaaa aaaaccggct
     4081 ctatttaaga accgggctcg gcgttttcat cctgtgatgt atgcagatac cgcaaaaata
     4141 attgatagga acaaaaaaca ttttgctgaa gcatagccaa aaagttcatt tgcagctgcg
     4201 gatgataaga catcattttc ttaaatatgt aatatgggat gttgagaatc agaatgtctg
     4261 aagtggcatt gactgagata aagggcgata aataaagccc gcctttttca tcaatcggaa
     4321 acacatcgcc tttttcccac agcgcaacgg ttttcgaccc ttcagggagc cttgtgtcca
     4381 taaaacggac actgcctttt aatacaatat aaacagattg agaatgaaga aaagatggag
     4441 actgatcaca tgagccgcgg ataaacgtgc cgtttttcag caaggtttcg acaatggata
     4501 gaggcacttc attaaacata ggaagttgtt tcagaaataa taaatagtca cactgattca
     4561 taggaaaacc tcctgtgcta aggatagctt tagtgtagct cgactgagcc tgtacagcag
     4621 tgatgtattt cacagcctgt atgatgaatg tcacttatca ggagggtgac tgcatttata
     4681 atgaaagaaa aaaggaggat ttcgatgaag gcgctgattc cgaagcagca cggcgcgtgg
     4741 gcgatgctgc tgatcccatt tttactcggc atggtcaagg gaggccccgt tatttggcat
     4801 attccgctct tccttggttg gcttttccta tacttagcgg tttatcccgt tacgcttgcc
     4861 ttaaaaaaga aacaaagcaa accatatcaa aagtggatgt gttattacgg ttttcccgcc
     4921 tgctgctttt tgatgatctc ggtctttcat aagccgcctc tcatctgggt gggcgtttct
     4981 ttactgccgc tgtttctcat acatatgtat tttgcccgca gaaaaaacga acgagcctta
     5041 ttgaatgatg ttgcaggtgt cttgttcttt tgttcgggcg ggtttgcgag ctgctggctg
     5101 gggatgggaa cccttgacgg ctgggcttgg tttattttct tgcagtctgc tttatttttt
     5161 atcgggagtt ccttttatgt gaaatcggtg atccgcgaga gaaaaaacag ggcatttgca
     5221 tactggtcat ggggatatca cctgctgctc ccctttttat ccgctctttt cggagcagga
     5281 tgggcgtttc tcgcttttat cccgagcagc ttgcgggcat ggttttttca tggaagggat
     5341 tggcccgtaa aaacgattgg cattctggaa atcgtgaatg cctgcttctt tcttgccgtc
     5401 atgtgcctgt ttatcacaag gtaaaaaaac aaggacaccg ctgtccttgt ttttttcagt
     5461 caatattgca aatctccagc gggcaatttt cacactcaat ctcacatcgt aaatagtccc
     5521 gcttgtgcaa aataattttt ccggattcgt ctatcgaaat aacccctttt ttgcggagat
     5581 ctcccagcat acggttgatg ctttcccgtg cagccgcaca aaactttgcc aaatcctgat
     5641 ttgtcaggac aatgttaatc agaatgccgt cgcttcgctc cactccgtag ctgtttgata
     5701 agcggataag ggtagaatag agcgccccct ttttgccatg aagaagcaga tccctgattt
     5761 tggactgaat cttccggagg tgcgtgctca tccatttcat gaactcaaat gtcaaagcgc
     5821 cgttttggat taattctttt tccagtttat ttttattaat gacgagcacc tcgccatcct
     5881 ctagcacttt tgcactgagc atataccttg gttcttcagt gaaaagtgtt aattctccga
     5941 cgatatcatg cttttggcag attctaagcg tcaggtcttt tccgtcagat gtcagcttgc
     6001 cgatttcaat gagtcctgat tgaatcagat aaagctcttc tgcatccatt ccttctcgaa
     6061 acaaatacgt gtgtttttcc atttttcttt tcgtgctgat cgattccagc aattcatgca
     6121 gatcgctgga tataagatca ctatcagatg gtcgaacaga gagaaaattc atgagctcac
     6181 ctcgaagaaa gtcacgttgt gtgtttattg taacgtgaat tgatttgtac ccatcgagaa
     6241 aaaactaaca atcttgtgaa tgcccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa cacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattggca
     6481 atccccgctt gcttcgaaaa atagaaaggc accagtttaa aaacagtccc atttcctacg
     6541 cctgagcaga cggccacagt taatgatcca aacgtataaa ggccgattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcccgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc aaacaaaacg tgcagtaagg caaagacagc cagcaaaacc
     6961 aaatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc accccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagaat ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgcggtcact
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgttcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagttagtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagcc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgtgc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ctgcacttcg cattgcaaag
     8041 aagtaacgca cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatac cccagcgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agcaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaac gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccgtgtcgat ttttccattt
     8461 tggtacagtg aagtttcgga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tgtccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acggtcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct cgccgcggta gccatcctcc ggcatcggtt tttccaatcc gagcgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg agcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccaactgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taaaatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtg atccagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg tggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctcta gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattcct tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcaa gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc ggaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcagagctgt ccttggggaa caggcaaaag gttgtattaa tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gattgaggtt ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 tgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat cgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtatcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gttcatatac
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagagcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtgatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaatacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catcagctca ccaatcgccc ttttgtattc gattgaaaaa aacgaccgga
    13381 tgctgcttat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatttcaa tcgccgcgag ctttctgaaa
    13861 ccaatcgaaa gcgcggcgga acctgaggaa gaaacaattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaatcat tgacgctttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgctgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgagaatc
    14161 gaaaagaaat tcactgatcc tttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccgaaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagat agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctac acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacaactgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcaaacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat caatgattta caaaaagcct ataaggctgc
    15541 ctaccaagcc catcggatga cactgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatggtgctg ggtgatgagg agcggatgga
    15721 agatacctgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgtcgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cattttttca
    15841 agagattcag caaacgtacc gtctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaaacac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctgggttca ggccgttgcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgatg ctgtgcggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcatta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcttcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcatac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacgtat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agtgctggca
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctgcca ttcagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttgatcta taaaatagct acatcgcaat cgcagacgga cccgcgccaa ccggaatcac
    16981 cgtcacggct gtataatcac ttgtgcggta cacggtcaca gcattgtcgt tgggctgtgc
    17041 cgcataaata tactgtttgt ccggcgttac ggcgaggtca aaggcgccgg ggagagacac
    17101 gtttgcaatg atcctctgtc tggccgtatt aactacatat aagttattaa tgagaaacgg
    17161 ttcactatat ggctctagaa aataagctct agtactatcg agagaaaata caatcgtcat
    17221 cagcgtttca aataaacggc tgaagtcccc tcccctgctt aatggagaca aactaatctc
    17281 cgttacacct ttcggccaca actcaccatt caacacgtac gcaaaatttc cagcgtaagg
    17341 agttgcaatt aaactgggaa attcaaatga atctatgata ctttctacca actgcccagt
    17401 atttacatca tatttatcaa ccgaccaact gcttccatta gcggtataga catactgtcc
    17461 attcggatca agagcaaagt ctaaagcgcc gggtatcgga atgacatcaa tgaccgattg
    17521 agaggccgtg ttaatcacat atatagatcc ggcggccatc acgtatgcga actcatctgt
    17581 tggatcaaat tcgatttttc tcggccctcc tccaacagta atggtattta tgatagttaa
    17641 tgttttatta tcaatcactg agacaaggtt ggtatttcca tggaggatat acgtgaatgc
    17701 tttatcgaaa gtaacgccta gattagttgg cacagcagaa aacgggattg tttttacaac
    17761 agtgtttaaa tctgcatcaa tgaccgaaac cgtgctgtct ccagtattgg cagtaaacac
    17821 atatgattga gggtctggcg atggcggtaa aacaagtgtc ccggccaccg taagcggact
    17881 gccgtagaaa ggcggtacaa tgagaagatc ttccactgtc atttgactaa aatcaggaca
    17941 gcggtcagac tgtgctgcat aataaacaac ttgatcaatc tcttcggtat gaatcaccga
    18001 aacagccccg tctccttgtc catattgatt tcgtacaggc gacacactga caagaagcgt
    18061 aatggtccct tgtactctca cggcatatcg aacaccgata ccttctggtt ccggcccagt
    18121 ctggattaag caaggctcac tgatacagga caaattgtct gtactccatg taacagccgc
    18181 tgacgcttct gccgaatcaa ccttgaagcc ctcagggata tctatcggca cttgaaacgg
    18241 cgcttcccgg ctaatttcct catcacaaaa acagaaacaa ttttcctgta aagcagaaag
    18301 atcattcttt ttcatgattt cacgtccttt tagaaatgca caacatgcag cggttaaatc
    18361 gtaatggcac ccggtgaaac cccaagagat atcacagttt cctcagaata atcatctgtg
    18421 ttgtaaacaa tgatgctctg ttctataaaa cgagttgcat acagaaaatc gccattcggg
    18481 gtaaacgcat agtctgttgc tgattgcgga agatttccaa ttacacctgc tccattcgga
    18541 ctgacagaat ataaattgcc agtgaagctg tcatgtaaat acacctctga tccactcgta
    18601 aacattacat atagcccgtc aggctccagc tcttgggtat ccctgatcgt aaacgtattt
    18661 aaatcaataa ccgtcaaata attgaataag aattcttgtt ctaatacata cgcataccgc
    18721 tccgtagaat ctgtttctat ggatgatacg ataagctctc gttcaatcgt tcctaagact
    18781 tcaccggtag ataagtccac tttttgcact aacccaaaat taagaacata ggcgaacaac
    18841 ccattggggt caattgcaat atcaaaacct tctacaggaa tagacctctc aacagtcaac
    18901 gtatcaattc caatcacata aatggcagta ccggtgaaaa cataagcaaa ctcatgatta
    18961 gggataaatc taatcaatcg aggcggctga tccagcaata tagttgctgt cactgttaat
    19021 gtgtcataat cgatgacaga aatcacatta ttgttgggat gtaagacaaa cacagcgctt
    19081 ttatctggcg taatttcaat acctgccgga ttgtacggaa gagcaatcgt tgtcacaaca
    19141 gtatgggtgt ttgtatcaat cacagaaact gattgatcat ttggattcgc tgtaaacgcg
    19201 tagacgggtt ccggctccgg tacaagcaca atcgtccccg tcaccgataa aggactgccg
    19261 taaaacggcg gaacaacaac aaggttctca atcgtgatgt cactgatatc cgggcaatca
    19321 tccggttcat cggaataata gacgacttga tcgatttctg cattgtgaat gacggaaaca
    19381 gccccgtccc cttgtccata ttgatttcgc acaggtgaga cactgacgag tagcgtaacg
    19441 gttccctgca ggcgcactgc aaattgaaca ccgacctcat caggctctgg ccccgtttga
    19501 attaagcaac ggtcactgac acaagaaagg ctgtctgcat tccacgtcac gtttgcaaca
    19561 gcttcagccg gatcaacgac aaatccttca ggtaattcaa tcggcgcttg aaacatggct
    19621 tctcggcttg cttctccctc acaaaaacat aagcactctt cttgttctgc tcctgctttt
    19681 tctttaaagg aaagcttatt ttttctcatt ccttcacttc cttttcagac atacactgct
    19741 cacgcagata taacagaata tggaagagta acgtgtttgc ttgtacaaat tactgagggt
    19801 aaaagcttct ttttgaaaat atatctccaa acatgcggtg taacgaaaga aaaaattgcg
    19861 gtttttttgc gcttctcaca agaatgttga tgataaaata tgacatatat agaattatga
    19921 agggagggat ttgcaaacgt gacaggtgtc atatcttctt cttccatcgg agaaaagatt
    19981 aacgaatggt atatgtacat acgccgattc agcatacccg atgcagaata tttgcgacga
    20041 gaaatcaagc aagagctgga tcaaatggaa gaagatcaag accttcattt gtactattca
    20101 ctgatggagt ttcggcacaa cctaatgctt gagtaccttg aaccgttaga aaaaatgagg
    20161 attgaggaac agccgagact gtctgatctg ctgcttgaga ttgataaaaa acaggctcgt
    20221 ttaactggtc tgcttgagta ctattttaat ttcttcagag gcatgtatga gctggaccag
    20281 cgggaatatc tgtcggctat taaatttttc aaaaaggccg aaagcaagct gatattcgtt
    20341 aaggatcgga tagagaaagc tgagtttttc tttaagatgt ctgaatctta ttactatatg
    20401 aaacaaacgt atttttcaat ggactatgca cggcaagcat atgaaatata caaagaacat
    20461 gaagcttata atataagatt gctgcagtgt cattctttat ttgccaccaa ttttttagat
    20521 ttaaaacagt atgaggatgc catctcacat tttcaaaaag cttattctat ggcagaagct
    20581 gaaaagcagc cccaattaat ggggagaact ttgtacaata tcgggctttg taaaaacagc
    20641 caaagccaat atgaggatgc cataccttat ttcaaaagag caatagctgt ttttgaagaa
    20701 tcaaatattc ttccttcctt acctcaagcg tattttttaa ttacacagat ccattataaa
    20761 ttaggaaaaa tggataaagc acatgaatat catagtaagg gaatggctta ttcacaaaag
    20821 gccggagatg taatatattt atcagagttt gaatttttga aatctttata cttatcaggc
    20881 ccggatgaag aagcaattca aggatttttt gattttctcg aaagtaaaat gttgtatgct
    20941 gatcttgaag atttcgctat tgatgtggca aaatattatc atgaacgtaa aaattttcaa
    21001 aaagcttctg cttatttttt gaaggtggaa caagtaaggc aacttattca aggaggagtg
    21061 agtttgtatg aaattgaagt ctaaactatt actctcttgt ctggctctaa gcactgtgtt
    21121 cgtggcaaca actattgcaa atgcacctac acaccaaatt gaagttgcac aacgaggaat
    21181 gatttaaaca cttaaaatat aaaaagggaa atgttatttc gttaacattt ccctttttat
    21241 atttattcac ttagaaattt atcagccttt tcacttcctt taaattaaat attaataaac
    21301 aaatgaattt ttccttaaat ttcatttact tttcctgtat tatacattat tatatatagg
    21361 acttaagtta tctataatct tcaattgaag aatactcgga ggaataataa caaatgaaat
    21421 ttacagttaa aaaacatata agtaaaatgt ttataatatt tgggcttgct gtttcatctt
    21481 ttggagtcac aagtgctgtg catgccgctg ccaatacttc tgattcaact gtccatttta
    21541 cttttagagt atggtctcct tatgattata caactgcacg cagaaaacag aacaaaagct
    21601 ctatgtatat ga
//
