LOCUS       NZ_QRFZ01000007        25183 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis subsp. subtilis strain EA-CB0575 BS575_7, whole
            genome shotgun sequence.
ACCESSION   NZ_QRFZ01000007
VERSION     NZ_QRFZ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis subsp. subtilis
  ORGANISM  Bacillus subtilis subsp. subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 215961)
  AUTHORS   Franco-Sierra,N.D., Posada,L.F., Santa-Maria,G., Romero-Tabarez,M.,
            Villegas-Escobar,V. and Alvarez,J.C.
  TITLE     Bacillus subtilis EA-CB0575 genome reveals clues for plant growth
            promotion and potential for sustainable agriculture
  JOURNAL   Funct Integr Genomics 20 (4), 575-589 (2020)
   PUBMED   32198678
REFERENCE   2  (bases 1 to 215961)
  AUTHORS   Franco-Sierra,N.D., Santa-Maria,G. and Alvarez,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) Process Engineering, Universidad EAFIT, Cra
            49 7 sur 50, Medellin, Antioquia 050022, Colombia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-MAR-2015
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 110.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011800745.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:42:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,261
            CDSs (total)                      :: 4,164
            Genes (coding)                    :: 4,041
            CDSs (with protein)               :: 4,041
            Genes (RNA)                       :: 97
            rRNAs                             :: 4, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1 (5S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 123
            CDSs (without protein)            :: 123
            Pseudo Genes (ambiguous residues) :: 0 of 123
            Pseudo Genes (frameshifted)       :: 62 of 123
            Pseudo Genes (incomplete)         :: 65 of 123
            Pseudo Genes (internal stop)      :: 19 of 123
            Pseudo Genes (multiple problems)  :: 21 of 123
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:02:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 25183
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QRFZ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25183
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..25183
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25183
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1355:5183](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1356..5183
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            <1..1319
                     /locus_tag="DXT72_RS01805"
     aSDomain        <7..830
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01805_Epimerization.1"
                     /evalue="7.80E-139"
                     /label="DXT72_RS01805_Epimerization.1"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="275"
                     /protein_start="0"
                     /score="455.7"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="MLHAKKGFDPERVEKTLQALIEHHDALRMVYREENGDIVQAYQPI
                     SESKVSFEIVDLYGSDEEMLRSQIKILANKLQSSLDLQNGPLLKAEQYRTEAGDHLLIA
                     VHHLVVDGVSWRILLEDFASGYMQAEKEESLVFPQKTNSFKDWAEELAAFSQSAHLLQQ
                     AEYWSQIAAEQVSPLPKDCKTEQRIVKDTSSVLCELTEEDTKHLLTDVHQPYGTEINDI
                     LLSALGLTMKEWTKGAKIGINLEGHGREDIIPNVNISRTVGWFTAQYPVVLDI"
     aSModule        <7..1289
                     /domains="nrpspksdomains_DXT72_RS01805_Epimerization.1"
                     /domains="nrpspksdomains_DXT72_RS01805_TIGR01720.1"
                     /incomplete
                     /locus_tags="DXT72_RS01805"
                     /tool="antismash"
                     /type="unknown"
     CDS             <5..1319
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Epimerization (0-275). E-value:
                     7.8e-139. Score: 455.7. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01805_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (279-428). E-value: 7.3e-55.
                     Score: 177.0. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01805_TIGR01720.1"
                     /codon_start=3
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388231.2"
                     /locus_tag="DXT72_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_167407846.1"
                     /sec_met_domain="Condensation (E-value: 3.1e-74, bitscore:
                     243.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHAKKGFDPERVEKTLQALIEHHDALRMVYREENGDIVQAYQPI
                     SESKVSFEIVDLYGSDEEMLRSQIKILANKLQSSLDLQNGPLLKAEQYRTEAGDHLLIA
                     VHHLVVDGVSWRILLEDFASGYMQAEKEESLVFPQKTNSFKDWAEELAAFSQSAHLLQQ
                     AEYWSQIAAEQVSPLPKDCKTEQRIVKDTSSVLCELTEEDTKHLLTDVHQPYGTEINDI
                     LLSALGLTMKEWTKGAKIGINLEGHGREDIIPNVNISRTVGWFTAQYPVVLDISDADAS
                     AVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNYLGQFDSEVKTDFFEPS
                     AFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFERATVEEQMERFKENLLML
                     IRHCTEKEDKEFTPSDFSAEDLEMDEMGDIFDMLEENLK"
     CDS_motif       27..101
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01805_0001"
                     /evalue="1.50E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="32"
                     /protein_start="7"
                     /score="20.6"
                     /tool="antismash"
                     /translation="FDPERVEKTLQALIEHHDALRMVYR"
     CDS_motif       306..371
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01805_0002"
                     /evalue="2.70E-12"
                     /label="NRPS-E2"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="122"
                     /protein_start="100"
                     /score="38.7"
                     /tool="antismash"
                     /translation="LLIAVHHLVVDGVSWRILLEDF"
     CDS_motif       774..824
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01805_0003"
                     /evalue="1.00E-08"
                     /label="NRPS-E5"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="273"
                     /protein_start="256"
                     /score="27.1"
                     /tool="antismash"
                     /translation="NISRTVGWFTAQYPVVL"
     aSDomain        843..1289
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01805_TIGR01720.1"
                     /evalue="7.30E-55"
                     /label="DXT72_RS01805_TIGR01720.1"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="428"
                     /protein_start="279"
                     /score="177.0"
                     /tool="antismash"
                     /translation="ASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNY
                     LGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFERA
                     TVEEQMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGD"
     CDS_motif       864..923
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01805_0004"
                     /evalue="6.30E-12"
                     /label="NRPS-E6"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="306"
                     /protein_start="286"
                     /score="37.5"
                     /tool="antismash"
                     /translation="VKENLRRIPDKGVGYGILRY"
     CDS_motif       957..986
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01805_0005"
                     /evalue="1.10E-03"
                     /label="NRPS-E7"
                     /locus_tag="DXT72_RS01805"
                     /protein_end="327"
                     /protein_start="317"
                     /score="11.3"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        1356..1451
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01810_NRPS-COM_Nterm.1"
                     /evalue="1.50E-16"
                     /label="DXT72_RS01810_NRPS-COM_Nterm.1"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="32"
                     /protein_start="0"
                     /score="51.3"
                     /tool="antismash"
                     /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQ"
     gene            1356..5183
                     /gene="srfAC"
                     /locus_tag="DXT72_RS01810"
     CDS             1356..5183
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.5e-16.
                     Score: 51.3. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01810_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value:
                     4e-119. Score: 389.1. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01810_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-867). E-value:
                     1.4e-111. Score: 365.0. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01810_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (973-1042). E-value: 1.4e-25. Score:
                     81.3. Matches aSDomain: nrpspksdomains_DXT72_RS01810_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1060-1255). E-value:
                     5.6e-37. Score: 120.3. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01810_Thioesterase.1"
                     /codon_start=1
                     /gene="srfAC"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388233.2"
                     /locus_tag="DXT72_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="surfactin non-ribosomal peptide synthetase SrfAC"
                     /protein_id="WP_167407847.1"
                     /sec_met_domain="Condensation (E-value: 2e-93, bitscore:
                     306.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-121, bitscore:
                     398.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.9e-18, bitscore:
                     58.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.2e-49, bitscore:
                     162.5, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKG
                     SLNIKCLEESMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQT
                     AKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLF
                     KVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEGFEGQTTFAEQRKKQ
                     KDGYEPKELLFSLSEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVV
                     SGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKQLQEQSLQSEPHQYVPLYDIQ
                     SQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMASPGDEML
                     IKLAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINLVDDREREFLLTGLNPPA
                     QAHETKPLTYWFKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQKHGAGKGSVV
                     ALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKEQAA
                     ELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNKTTHANIQGL
                     VKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTDLIL
                     QENVNVMFATTALFNLLTDAGEDWMKGLRCVLFGGERASVPHVRKALRVMGPGKLINCY
                     GPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCISGMG
                     VSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRI
                     ELEEIEKQLQEYPGVKDAVVVADRPESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYM
                     VPQTFTFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQ
                     IGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAPTIAGISAYLKNGGSDGLQ
                     DVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLIQK
                     LQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVESDV
                     EALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPE
                     WLASWEEATTGVYRVKRGFGTHAEMLQGETLDRNAGILLEFLNTQTVTVS"
     aSDomain        1383..2279
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01810_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.00E-119"
                     /label="DXT72_RS01810_Condensation_DCL.1"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="308"
                     /protein_start="9"
                     /score="389.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIILDG"
                     /tool="antismash"
                     /translation="QDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKGSLNIKCLEE
                     SMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQTAKINEYKEQ
                     DKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLFKVYNALREQ
                     KPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEGFEGQTTFAEQRKKQKDGYEPKEL
                     LFSLSEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVVSGRPAEIKG
                     VEHMVGLFINVVPRRVKL"
     aSModule        1383..5120
                     /complete
                     /domains="nrpspksdomains_DXT72_RS01810_Condensation_DCL.1"
                     /domains="nrpspksdomains_DXT72_RS01810_AMP-binding.1"
                     /domains="nrpspksdomains_DXT72_RS01810_PCP.1"
                     /domains="nrpspksdomains_DXT72_RS01810_Thioesterase.1"
                     /final_module
                     /locus_tags="DXT72_RS01810"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1392..1433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0001"
                     /evalue="3.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="26"
                     /protein_start="12"
                     /score="15.8"
                     /tool="antismash"
                     /translation="YYLSPMQEGMLFHA"
     CDS_motif       1455..1571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0002"
                     /evalue="2.50E-12"
                     /label="C2_DCL_024-062"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="72"
                     /protein_start="33"
                     /score="39.1"
                     /tool="antismash"
                     /translation="FYLEQITMKVKGSLNIKCLEESMNVIMDRYDVFRTVFIH"
     CDS_motif       1788..1853
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0003"
                     /evalue="1.70E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="166"
                     /protein_start="144"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YHHIILDGWCFGIVVQDLFKVY"
     CDS_motif       1899..1937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0004"
                     /evalue="5.50E-04"
                     /label="C4_DCL_171-183"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="194"
                     /protein_start="181"
                     /score="12.4"
                     /tool="antismash"
                     /translation="PYKDYIKWLEKQD"
     CDS_motif       2175..2270
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0005"
                     /evalue="1.30E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="305"
                     /protein_start="273"
                     /score="59.4"
                     /tool="antismash"
                     /translation="DLAFGTVVSGRPAEIKGVEHMVGLFINVVPRR"
     CDS_motif       2319..2432
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0006"
                     /evalue="1.00E-17"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="359"
                     /protein_start="321"
                     /score="56.6"
                     /tool="antismash"
                     /translation="QEQSLQSEPHQYVPLYDIQSQADQPKLIDHIIVFENYP"
     aSDomain        2763..3956
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01810_AMP-binding.1"
                     /evalue="1.40E-111"
                     /label="DXT72_RS01810_AMP-binding.1"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="867"
                     /protein_start="469"
                     /score="365.0"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FKEAVNANPDAPALTYSGQTLSYRELDEEANRIARRLQKHGAGKG
                     SVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKE
                     QAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNKTTHANI
                     QGLVKHVDYMAFSDQDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTD
                     LILQENVNVMFATTALFNLLTDAGEDWMKGLRCVLFGGERASVPHVRKALRVMGPGKLI
                     NCYGPTEGTVFATAHVVHDLPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCIS
                     GMGVSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIR"
     CDS_motif       2949..2990
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0007"
                     /evalue="2.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="545"
                     /protein_start="531"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LGVLKAGAAYLPVD"
     CDS_motif       3183..3242
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0008"
                     /evalue="2.90E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="629"
                     /protein_start="609"
                     /score="22.9"
                     /tool="antismash"
                     /translation="AYIMYTSGTTGKPKGNKTTH"
     CDS_motif       3750..3839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0009"
                     /evalue="5.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="828"
                     /protein_start="798"
                     /score="41.1"
                     /tool="antismash"
                     /translation="PFGAIGELCISGMGVSKGYVNRADLTKEKF"
     CDS_motif       3921..3986
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0010"
                     /evalue="9.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="877"
                     /protein_start="855"
                     /score="36.8"
                     /tool="antismash"
                     /translation="YAGRIDDQVKIRGHRIELEEIE"
     aSDomain        4275..4481
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01810_PCP.1"
                     /evalue="1.40E-25"
                     /label="DXT72_RS01810_PCP.1"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="1042"
                     /protein_start="973"
                     /score="81.3"
                     /tool="antismash"
                     /translation="EETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELG
                     IDLPVKLLFEAPTIAGISAYLKNG"
     aSDomain        4536..5120
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01810_Thioesterase.1"
                     /evalue="5.60E-37"
                     /label="DXT72_RS01810_Thioesterase.1"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="1255"
                     /protein_start="1060"
                     /score="120.3"
                     /tool="antismash"
                     /translation="IFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLI
                     QKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVES
                     DVEALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDM
                     PEWLASWEEATTGVYRVKRGFGTHAEMLQGET"
     CDS_motif       4680..4754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01810_0011"
                     /evalue="6.30E-10"
                     /label="NRPS-te1"
                     /locus_tag="DXT72_RS01810"
                     /protein_end="1133"
                     /protein_start="1108"
                     /score="31.5"
                     /tool="antismash"
                     /translation="QPEGPLTLFGYSAGCSLAFEAAKKL"
     gene            5212..5940
                     /gene="srfAD"
                     /locus_tag="DXT72_RS01815"
     CDS             5212..5940
                     /NRPS_PKS="Domain: Thioesterase (14-231). E-value: 3.9e-55.
                     Score: 179.7. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01815_Thioesterase.1"
                     /codon_start=1
                     /gene="srfAD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388234.1"
                     /locus_tag="DXT72_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="surfactin biosynthesis thioesterase SrfAD"
                     /protein_id="WP_003234568.1"
                     /sec_met_domain="Thioesterase (E-value: 9e-70, bitscore:
                     229.2, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.8e-15, bitscore:
                     50.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.5e-06, bitscore: 21.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAA
                     EPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGI
                     FPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSD
                     YRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQ
                     TEEVAERIFAILNQHPIIQP"
     aSDomain        5254..5904
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01815_Thioesterase.1"
                     /evalue="3.90E-55"
                     /label="DXT72_RS01815_Thioesterase.1"
                     /locus_tag="DXT72_RS01815"
                     /protein_end="231"
                     /protein_start="14"
                     /score="179.7"
                     /tool="antismash"
                     /translation="QLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIE
                     DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAIQPPH
                     IQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQ
                     IQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIF"
     CDS_motif       5437..5508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXT72_RS01815_0001"
                     /evalue="1.90E-08"
                     /label="NRPS-te1"
                     /locus_tag="DXT72_RS01815"
                     /protein_end="99"
                     /protein_start="75"
                     /score="26.7"
                     /tool="antismash"
                     /translation="PDRPFVLFGHSMGGMITFRLAQKL"
     gene            6041..7267
                     /gene="srfT"
                     /locus_tag="DXT72_RS01820"
     CDS             6041..7267
                     /codon_start=1
                     /gene="srfT"
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388235.2"
                     /locus_tag="DXT72_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_167407848.1"
                     /transl_table=11
                     /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS
                     LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLVLPYSPNVHVFSAI
                     YGVLGGIGYSCAVGVTTQYFISRWFDTHKGLALAILTNANSAGLLLLSPIWAAAPYHAG
                     WQSTYTILGIVMAAVLLPLLVFGMKHPPHAQAETVKKSYDWRGFWNVMKQSRLIHILYF
                     GVFTCGFTMGIIDAHLVPILKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM
                     LSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASTSESYQTGL
                     IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFLDKQ
                     KAKETHHSI"
     gene            complement(7282..7839)
                     /gene="ycxB"
                     /locus_tag="DXT72_RS01825"
     CDS             complement(7282..7839)
                     /codon_start=1
                     /gene="ycxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388236.1"
                     /locus_tag="DXT72_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcxB family protein"
                     /protein_id="WP_003234558.1"
                     /transl_table=11
                     /translation="MIQYANESINLPGEIAFKDVREIFFYQIAKISCFYFLLFCAIFAA
                     VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR
                     TYTLNQEGICISSKKYNLIFNWNEITAVFEYKNIFRINTSSSQYIAIPKHFFHSEEEMN
                     RFKEIILKNTETKKLKFKKDQH"
     gene            complement(7893..8831)
                     /gene="ycxC"
                     /locus_tag="DXT72_RS01830"
     CDS             complement(7893..8831)
                     /codon_start=1
                     /gene="ycxC"
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388237.2"
                     /locus_tag="DXT72_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_167407849.1"
                     /transl_table=11
                     /translation="MVKHQQAPAYIAAILYSFIIGLSFLFVKIALQTAEPFDILAHRFT
                     IAFAAATVPILFGWVKLSIRVKDVIAILPLALLYPALFFSFQAFGLVDSSSSEAGIIQA
                     AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA
                     LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPFREPG
                     FVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGVVILNESLAWYH
                     LAGAVCIMIGVVGSNINLEKKTKRPGMPAKK"
     misc_feature    complement(8861..8875)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            8955..10289
                     /gene="ycxD"
                     /locus_tag="DXT72_RS01835"
     CDS             8955..10289
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (96-438). E-value:
                     1.7e-22. Score: 72.0. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01835_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="ycxD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388238.1"
                     /locus_tag="DXT72_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_167407850.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6.1e-22, bitscore:
                     72.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKYMSLVTRIEEMRQSTAYQEGDRLPSIRQLSARYQVSKSTVIR
                     ALQELEKRHLIYSVPKSGYYIVKKTGKSKSGQPGPIDFATSAPDPDVFPYLDFQHCINK
                     AIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCAMPF
                     PNGKEKIAIEQPGYHLMVEQLETLGISAIGVKRTEEGLDIAEVERLFQTESIKFFYTMP
                     RFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYL
                     KSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKE
                     KIRNSYKERSLRLHQAIQTHRQLGSGRFTFSSGQALCMHTHLVLPQDLPASRVIHRLKK
                     QGVILEAIDRHYLSDYQKENLLKINISNVKTEDIERGVKLLMSHL"
     aSDomain        9243..10268
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01835_Aminotran_1_2.1"
                     /evalue="1.70E-22"
                     /label="DXT72_RS01835_Aminotran_1_2.1"
                     /locus_tag="DXT72_RS01835"
                     /protein_end="438"
                     /protein_start="96"
                     /score="72.0"
                     /tool="antismash"
                     /translation="DFQHCINKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFAD
                     ERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGYHLMVEQLETLGISAIGVKRTEEG
                     LDIAEVERLFQTESIKFFYTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGD
                     LEENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDC
                     SMISQAALEIYLKSGMYGRHKEKIRNSYKERSLRLHQAIQTHRQLGSGRFTFSSGQALC
                     MHTHLVLPQDLPASRVIHRLKKQGVILEAIDRHYLSDYQKENLLKINISNVKTEDIERG
                     VK"
     gene            complement(10284..10958)
                     /locus_tag="DXT72_RS01840"
     CDS             complement(10284..10958)
                     /EC_number="2.7.8.7"
                     /NRPS_PKS="Domain: ACPS (103-166). E-value: 6.5e-20. Score:
                     63.4. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01840_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234549.1"
                     /locus_tag="DXT72_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="WP_015715234.1"
                     /transl_table=11
                     /translation="MKIYGIYMDRPLSQEENERFMTFISPEKREKCRRFYHKEDAHRTL
                     LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDSQPI
                     GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSL
                     PLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEE
                     LL"
     aSDomain        complement(10461..10649)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01840_ACPS.1"
                     /evalue="6.50E-20"
                     /label="DXT72_RS01840_ACPS.1"
                     /locus_tag="DXT72_RS01840"
                     /protein_end="166"
                     /protein_start="103"
                     /score="63.4"
                     /tool="antismash"
                     /translation="IGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWS
                     MKESFIKQEGKGLSLPLD"
     misc_feature    complement(11034..11043)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            complement(11063..11710)
                     /gene="yczE"
                     /locus_tag="DXT72_RS01845"
     CDS             complement(11063..11710)
                     /codon_start=1
                     /gene="yczE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388240.2"
                     /locus_tag="DXT72_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YitT family protein"
                     /protein_id="WP_003234545.1"
                     /transl_table=11
                     /translation="MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLF
                     QHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPAPSTYT
                     GSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMELTILFA
                     AWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH"
     gene            complement(11830..12573)
                     /gene="tcyC"
                     /locus_tag="DXT72_RS01850"
     CDS             complement(11830..12573)
                     /codon_start=1
                     /gene="tcyC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388241.2"
                     /locus_tag="DXT72_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cystine ABC transporter ATP-binding protein TcyC"
                     /protein_id="WP_003234543.1"
                     /transl_table=11
                     /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR
                     CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME
                     GPIQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML
                     FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG
                     PPEQIFSAPKEERTQRFLNRILNPL"
     gene            complement(12587..13291)
                     /gene="tcyB"
                     /locus_tag="DXT72_RS01855"
     CDS             complement(12587..13291)
                     /codon_start=1
                     /gene="tcyB"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388242.1"
                     /locus_tag="DXT72_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cystine ABC transporter permease TcyB"
                     /protein_id="WP_003234541.1"
                     /transl_table=11
                     /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIF
                     GMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSA
                     VIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLS
                     NTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQH
                     VIERRLDRYVAK"
     gene            complement(13278..14084)
                     /gene="tcyA"
                     /locus_tag="DXT72_RS01860"
     CDS             complement(13278..14084)
                     /codon_start=1
                     /gene="tcyA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388243.2"
                     /locus_tag="DXT72_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cystine ABC transporter substrate-binding
                     lipoprotein TcyA"
                     /protein_id="WP_015382752.1"
                     /transl_table=11
                     /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKG
                     VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK
                     RFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNY
                     NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGD
                     PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK"
     misc_feature    complement(14120..14129)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(14200..15072)
                     /gene="bsdA"
                     /locus_tag="DXT72_RS01865"
     CDS             complement(14200..15072)
                     /codon_start=1
                     /gene="bsdA"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388244.1"
                     /locus_tag="DXT72_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator BsdA"
                     /protein_id="WP_003234533.1"
                     /transl_table=11
                     /translation="MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGV
                     VLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAA
                     LMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDI
                     PCVLVLSDEAGYPCGDTIKMEDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPRIVCE
                     CHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPK
                     PAQQFLDLF"
     gene            15162..15776
                     /gene="ubiX"
                     /locus_tag="DXT72_RS01870"
     CDS             15162..15776
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ubiX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388245.1"
                     /locus_tag="DXT72_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="non-oxidative hydroxyarylic acid decarboxylases
                     subunit B"
                     /protein_id="WP_014478815.1"
                     /sec_met_domain="Flavoprotein (E-value: 1.7e-32, bitscore:
                     105.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVETHLV
                     VSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKSLAS
                     IRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMPAFY
                     NQPSSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA"
     gene            15779..17200
                     /gene="bsdC"
                     /locus_tag="DXT72_RS01875"
     CDS             15779..17200
                     /codon_start=1
                     /gene="bsdC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388246.1"
                     /locus_tag="DXT72_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenolic acid decarboxylase BsdC"
                     /protein_id="WP_003240157.1"
                     /transl_table=11
                     /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGAAARAASNLGDK
                     SPALLFNNIYGYHNAQIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK
                     REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI
                     YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ
                     SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG
                     RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN
                     AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA
                     LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL
                     TTKEWEQKLMDLMNK"
     gene            17217..17444
                     /gene="bsdD"
                     /locus_tag="DXT72_RS01880"
     CDS             17217..17444
                     /codon_start=1
                     /gene="bsdD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097675.1"
                     /locus_tag="DXT72_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenolic acid decarboxylase subunit BsdD"
                     /protein_id="WP_010886405.1"
                     /transl_table=11
                     /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESIT
                     NPEKYNPAFKIDPKETETAIEVPAVPERKA"
     gene            17441..17905
                     /gene="yclD"
                     /locus_tag="DXT72_RS01885"
     CDS             17441..17905
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /GO_function="GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="yclD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388247.2"
                     /locus_tag="DXT72_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_032730553.1"
                     /transl_table=11
                     /translation="MIRVNSLSDRLFELLDGRCLSEKQHEAFVLQTVSEDGWPHAAMIS
                     AGEIIALSRTDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKDAE
                     YDRDRFSCRIVSVKEDVAKYADLTSGVRIQLHSAEEVLSRWEKTLEDLKR"
     misc_feature    complement(17935..17948)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.96"
                     /tool="antismash"
     gene            17971..18816
                     /gene="yclE"
                     /locus_tag="DXT72_RS01890"
     CDS             17971..18816
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (29-268). E-value: 1e-18.
                     Score: 59.8. Matches aSDomain:
                     nrpspksdomains_DXT72_RS01890_Abhydrolase_1.1"
                     /codon_start=1
                     /gene="yclE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388248.2"
                     /locus_tag="DXT72_RS01890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_032722909.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-16, bitscore: 52.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.6e-09, bitscore:
                     31.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQK
                     YQWVFVDHRGFAKLKRGLRAEDSRLDAVLADIERMRTFLQFEDIIILGHSGHAFMALEY
                     ARTYPEHVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIANLPQDIEKDP
                     ERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIIDELWGNTFARIDLLQRLADVRM
                     PVYIGLGRYDYLVAPVSLWDAVDGLYPHVDKVIFEKSGHQPMLEEPEAFDQSFSKWLDQ
                     "
     aSDomain        18058..18774
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXT72_RS01890_Abhydrolase_1.1"
                     /evalue="1.00E-18"
                     /label="DXT72_RS01890_Abhydrolase_1.1"
                     /locus_tag="DXT72_RS01890"
                     /protein_end="268"
                     /protein_start="29"
                     /score="59.8"
                     /tool="antismash"
                     /translation="SAVYYPRLFSSDIKQKYQWVFVDHRGFAKLKRGLRAEDSRLDAVL
                     ADIERMRTFLQFEDIIILGHSGHAFMALEYARTYPEHVRKVALFNTAPDNSEERQRKSE
                     SFFMETASLERKKRFEKDIANLPQDIEKDPERRFVHMCIRAEAKSFYQERPHAAALWDG
                     VFTNMPIIDELWGNTFARIDLLQRLADVRMPVYIGLGRYDYLVAPVSLWDAVDGLYPHV
                     DKVIFEKSGHQPMLEEP"
     gene            complement(18857..20335)
                     /gene="dtpT"
                     /locus_tag="DXT72_RS01895"
     CDS             complement(18857..20335)
                     /codon_start=1
                     /gene="dtpT"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388249.2"
                     /locus_tag="DXT72_RS01895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide MFS transporter"
                     /protein_id="WP_043940051.1"
                     /transl_table=11
                     /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAI
                     LLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIF
                     IMFGHIALAYPGSSIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYM
                     GINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPL
                     SKKSAIGTGIGVIIVAIAVMISVQTGVLTINRFIDLVSILGILIPVIYFIIMFTSKKAD
                     STEKSRLAAYIPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPL
                     FVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLV
                     LSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIP
                     ETMYFGTIGLISIVLGGILLLLSPMIKRAMKGVL"
     misc_feature    complement(20366..20379)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     misc_feature    20525..20534
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    20526..20539
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.74"
                     /tool="antismash"
     misc_feature    20527..20540
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.27"
                     /tool="antismash"
     misc_feature    complement(20528..20541)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.88"
                     /tool="antismash"
     gene            20615..22369
                     /gene="yclG"
                     /locus_tag="DXT72_RS01900"
     CDS             20615..22369
                     /codon_start=1
                     /gene="yclG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388250.1"
                     /locus_tag="DXT72_RS01900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_032722911.1"
                     /transl_table=11
                     /translation="MAEFILNAADFGVPGDGKTDSTERINQCLSTAVSKGYHTVWFPKG
                     TYLIDATLGGDLNQRFRNAGIIVPGNLEIMMDPECIMKVIPNSSWGYSAFYVGKQENIT
                     ISGGQIIGERDEHTYASAGIRSTHEWGFGICIEGCSNVVIDDVKISDFTGDGIIVSPRG
                     LKTNQDYRTSEQIIIRRCEVRRSRRNNISITGCDMVTVEECLIEDAGTGNGTAPKFGID
                     IEGYGEGDVDYEEPINVSIRNNHFVGNVSSSVTNFNGYGILIEGNHSDNTISYGYGTQT
                     VIKGNILRRPEDAAAAPRVGITGLGVSQGKETSDAVIAGNLITGFSTGIDVRGKSVLVT
                     NNKISNFENTGILVYQSSDVKVDGNQIQNGLSETRRSIGLRAVLSDDIAFLNNCLIQVV
                     DGVNVSGGNMIIKDNLLRKFSRGIWIAQGNAVIEGNTLNPDAFEAVPESYSVSVTNNAG
                     AIIKNNTFKEFKNYPIYCSTSAKTSIIGNHLERSPLLVTIYISAGVHEIFDNTISVNRT
                     AGNPIVIYINGSAGSIVSGNTINNLSAGTATAIQTNTSTNSKIIGNRIFKGTINKHSSD
                     TIDGNFIV"
     gene            complement(22384..22605)
                     /locus_tag="DXT72_RS01905"
     CDS             complement(22384..22605)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388251.1"
                     /locus_tag="DXT72_RS01905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_015252828.1"
                     /transl_table=11
                     /translation="MKILGVTGVILICLLAISVLMDMLQGFSLTKAVYNNMSSFKMTTF
                     AEWVVILFFVLVLVREMYVIYKSKKKNP"
     misc_feature    22677..22691
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            22731..24365
                     /gene="gerKA"
                     /locus_tag="DXT72_RS01910"
     CDS             22731..24365
                     /codon_start=1
                     /gene="gerKA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388252.1"
                     /locus_tag="DXT72_RS01910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spore germination protein GerKA"
                     /protein_id="WP_080528919.1"
                     /transl_table=11
                     /translation="MPLFSKRKNNTSSKDKRNTEEKNQEQQQEKERPVLISPSLAKNIA
                     ETKKEVGSSSDVIIREIKIGEQDHVHLAVIYIAGLVDNNTIHESLIDPLVQDESIQNTH
                     AIQQILEKTLPLGGVKAEKSWDKLFSELMLGNALIFADGHDEALICSTQGGEQRSIQEP
                     STQVSFRGPRQGFTESLQTNISMIRRYIKNPNLWVEKMKKGSVTNTDIALMYIQGICDE
                     KVLKEVKQRLEKIDIDSILESGYIEQLIEDETFTTFPTMYHTERPDVVAGNLLEGRFAI
                     IVDGTPFVLIAPALFVQFFQSVEDYYSRFDIATSIRILRVLVFFISLVAPAVYVAATTF
                     HQEMIPTQLLVVIAAQREIVPFPAVVEALTMEVAFEILREAGVRLPRVVGSAVSIVGAL
                     VIGQAAVQAGIVSPAMVIIVALTAIASFATPAFAMAISARLIRFIFIIASAVMGFYGLI
                     LGIIMMFVHLCSLRSFGVPYMSPLAPFSSQGVKDALFRVPWWADEKRPESVSKEDKVRQ
                     GKDQRPEPAASRGMVNKDLEEGDQNGT"
ORIGIN
        1 tgatgcttca cgccaaaaag ggctttgatc ctgaacgggt ggagaaaaca ttgcaggcgc
       61 tgatcgagca tcatgacgcg ctccgtatgg tctatcgtga ggaaaacggg gacatcgttc
      121 aggcgtatca accgatcagt gagagcaagg tcagcttcga aatcgtggat ctgtacggct
      181 ccgatgaaga gatgctgaga agccagatta aaattctcgc gaacaagctg cagagcagtc
      241 tcgatctgca aaacgggccg cttctaaagg cggagcaata tcgcacagaa gctggggatc
      301 acctgctcat tgctgtacac catctcgtgg tcgacggtgt gtcatggcgg attttgcttg
      361 aagattttgc ttcaggctac atgcaggctg agaaagaaga gagccttgtc ttcccgcaaa
      421 aaacaaactc cttcaaggat tgggcggaag aactggcggc attcagccaa tcagcgcatc
      481 ttttacagca ggctgaatac tggtcgcaaa ttgccgctga acaggtttct cctttaccga
      541 aggattgtaa aacagagcag cggatcgtca aggatacatc atctgtccta tgtgaattaa
      601 cggaagaaga cacgaaacat cttttaacag atgttcatca gccatatgga actgaaatca
      661 acgatattct tctcagcgcg cttggtttga caatgaaaga atggacaaag ggtgccaaaa
      721 tcggcattaa ccttgaggga cacggccggg aggacatcat cccgaatgtg aatatctcca
      781 gaacggtcgg ctggtttacg gcacaatacc ctgttgtgct cgacatatct gacgcagatg
      841 cctcggctgt gatcaaaaca gtcaaagaaa acctgcgccg cattccggac aaaggtgttg
      901 gctacggcat tcttcgttat ttcacagaaa cagcggaaac aaagggcttc acaccggaga
      961 tcagcttcaa ctatttgggc caattcgaca gtgaagtcaa aaccgatttc tttgaaccgt
     1021 ccgctttcga tatgggacgc caagtaagcg gagaatcaga ggcgctgtac gcattaagct
     1081 tcagcggcat gatcagaaac ggccggtttg tgctttcctg ctcctacaat gagaaggagt
     1141 ttgaaagagc tacagtcgag gagcaaatgg aacggtttaa agaaaacctc ctgatgctaa
     1201 tccgccattg cacggaaaaa gaagacaagg aattcacacc aagcgacttc agcgccgaag
     1261 accttgaaat ggacgagatg ggagatatct ttgacatgct tgaggagaat ttaaaataaa
     1321 acgcaaggga attacagaag gcgggagcga aacatatgag tcaatttagc aaggatcagg
     1381 ttcaagatat gtattaccta tcgccgatgc aggaagggat gctttttcat gccatcctga
     1441 atcccggcca aagcttttac cttgaacaaa tcacgatgaa agtaaaaggc agcttgaata
     1501 tcaaatgtct tgaagaaagc atgaatgtga tcatggaccg gtacgatgta tttcgtaccg
     1561 tgttcattca cgaaaaagta aaaaggcctg tccaagtcgt attgaaaaaa cggcagttcc
     1621 atatagaaga aatcgatctg acacacttaa cgggcagcga gcaaacagcc aaaatcaatg
     1681 agtacaaaga acaggataag atcaggggtt ttgatttgac gcgggatatt ccgatgcggg
     1741 cagccatttt caagaaagct gaagaaagct ttgaatgggt gtggagctac caccacatta
     1801 ttttggacgg atggtgcttc ggcatcgtcg tacaggatct atttaaggta tacaatgctc
     1861 tgcgcgaaca aaagccgtac agcctgccgc ccgtcaaacc gtataaagac tacatcaagt
     1921 ggcttgaaaa gcaggataaa caagcatcac tgcgttactg gcgcgaatat ttagagggct
     1981 ttgaaggaca aacgacgttt gcggagcaaa gaaagaaaca aaaggacggc tatgagccga
     2041 aagagctgct cttttcactg tcggaggcgg aaacaaaggc ctttaccgag cttgcaaaat
     2101 cgcagcatac cactttgagt acggcgctgc aggcagtctg gagcgtattg atcagccgct
     2161 atcagcagtc tggcgatttg gccttcggta cagttgtttc agggcgtccc gcggaaatca
     2221 aaggcgttga acatatggtc gggctgttta tcaacgttgt cccgagacgt gtgaagctgt
     2281 ctgagggtat cacatttaac ggcttgctca agcagctgca ggagcaatcg ctgcagtccg
     2341 agccgcatca atatgtgccg ctttatgaca tccaaagcca ggccgatcag ccgaaactga
     2401 ttgaccacat cattgttttt gagaactatc cgcttcagga tgcgaaaaat gaagaaagca
     2461 gtgaaaacgg ctttgatatg gtggatgttc atgtttttga gaagtcgaat tatgatctca
     2521 acctgatggc ttccccggga gatgagatgc tgattaagct tgcctataat gagaatgtgt
     2581 ttgatgaggc gtttatcctg cgcttgaaat ctcagcttct tacagcaatt cagcagctca
     2641 tccagaatcc tgatcagcct gtcagcacga tcaacctcgt tgacgacagg gagagagaat
     2701 ttttgctaac cggcttaaac ccgccggctc aagctcatga aacaaagcct ctgacgtatt
     2761 ggttcaagga agcagtgaac gccaatccgg atgcaccggc gcttacgtat tccggccaga
     2821 ccctgtctta tcgcgaatta gatgaggaag cgaaccgcat tgcacgccgg ctgcaaaaac
     2881 acggtgcggg caaaggctct gttgtagcgc tgtacacgaa gcgctcactt gaactggtga
     2941 tcggcattct cggtgtatta aaggcgggag cagcctatct gccggttgat ccgaagctgc
     3001 cagaggaccg aatctcgtat atgctggctg acagtgcggc agcctgtctt ctgacgcatc
     3061 aggagatgaa agaacaagcg gctgagctgc cgtatacagg cacaacgctc ttcattgatg
     3121 atcaaacacg gtttgaagaa caggcaagcg atcctgcaac cgcgattgat cctaatgatc
     3181 cggcatatat catgtacacg tccggcacaa ccggaaagcc aaagggcaat aagaccactc
     3241 atgccaatat tcaaggtttg gtcaagcatg tagactacat ggcattttct gatcaggata
     3301 cgttcttgtc tgtttcgaat tacgcctttg acgcatttac ctttgatttc tatgcttcta
     3361 tgctgaatgc ggcacggctc attatcgcag atgaacatac gctgcttgat acagaacggc
     3421 tcacagatct gatcctgcaa gagaatgtca atgtcatgtt tgcgacaacc gcactattta
     3481 atcttctcac agatgcggga gaggattgga tgaaggggct tcgctgcgtg ttattcggcg
     3541 gagagcgcgc gtctgtgcct cacgtcagaa aagcgctgcg ggtcatgggg ccgggcaagc
     3601 tgattaactg ctacgggccg actgagggaa cagtgtttgc gacagctcac gtcgtgcatg
     3661 atctgccgga ttccatctcc tcattgccga ttggaaagcc gatcagcaat gccagtgttt
     3721 atattctgaa cgagcaaagc cagctccagc cattcggggc gatcggtgaa ctgtgcatca
     3781 gcggaatggg cgtgtcaaaa gggtatgtaa atcgtgctga cctcacgaag gaaaagttta
     3841 tcgagaaccc gttcaagccg ggagaaacgc tttaccgtac aggggattta gcgcgctggc
     3901 tgccggatgg aacgattgaa tacgccggcc gtattgacga ccaggtcaaa atacgcggac
     3961 accggattga gcttgaagaa atcgaaaagc agctgcagga atacccaggt gtgaaagatg
     4021 cggtcgttgt ggcggaccgc cctgagtctg gcgatgcatc aatcaatgcc taccttgtga
     4081 accgaacgca gctttcagct gaagacgtga aggcgcacct gaaaaaacag cttcctgctt
     4141 acatggtgcc gcaaaccttt accttcttgg atgagcttcc tttaacgacg aacgggaaag
     4201 tcaataaacg gctgctccca aaacctgatc aggatcagct ggcggaagaa tggattggac
     4261 cgcggaacga gatggaagaa acaatcgcac aaatatggtc tgaggttctc ggcagaaagc
     4321 aaattggcat tcatgacgat ttctttgcgc tcggagggca ttccttgaag gccatgaccg
     4381 ccgcgtcccg catcaagaaa gagctcggga ttgatcttcc agtgaagctt ttgtttgaag
     4441 cgccgacgat cgccggcatt tcagcgtatt tgaaaaacgg gggctctgat ggcttgcagg
     4501 atgtaacgat aatgaatcag gatcaggagc agatcatttt cgcatttccg ccggttctgg
     4561 gctatggcct tatgtaccaa aatctgtcca gccgcttgcc gtcatacaag ctatgcgcct
     4621 ttgattttat tgaggaggaa gaccggcttg accgctatgc ggatttgatc cagaagctgc
     4681 agccggaagg gcctttaaca ttgtttggat attcagcggg atgcagcctg gcgtttgaag
     4741 ctgcgaaaaa gcttgaggaa caaggccgta ttgttcagcg gatcatcatg gtggattcct
     4801 ataaaaaaca aggtgtcagt gatctggacg gacgcacggt tgaaagtgat gtcgaagcgt
     4861 tgatgaatgt caatcgggac aatgaagcgc tcaacagcga agccgtcaaa caaggcctca
     4921 agcaaaaaac acatgccttt tactcatact acgtcaacct gatcagcaca ggccaggtga
     4981 aagcagatat tgatctgttg acttccggcg ctgattttga catgccggaa tggcttgcat
     5041 catgggaaga agctacaaca ggtgtttacc gtgtgaaaag aggcttcgga acacacgcag
     5101 aaatgctgca gggcgaaacg ctagatagga atgccgggat tttgctcgaa tttcttaata
     5161 cacaaaccgt aacggtttca taaatgaagt gatgaaagga ggagacagcc aatgagccaa
     5221 ctcttcaaat catttgatgc gtcggaaaaa acacagctca tctgttttcc gtttgccggc
     5281 ggctattcgg cgtcgtttcg ccctctccat gcttttttgc agggggagtg cgagatgctc
     5341 gctgccgagc cgccgggaca cggcacgaat caaacgtcag ccattgagga tctcgaagag
     5401 ctgacggatt tgtacaagca agaactgaac cttcgccctg atcggccgtt tgtgctgttc
     5461 ggacacagta tgggcggaat gatcaccttc aggctggcgc aaaagcttga gcgtgaaggc
     5521 atctttccgc aggcggttat tatttctgca atccagccgc ctcatattca gcggaagaaa
     5581 gtgtcccacc tgcctgatga tcagtttctc gatcatatta tccaattagg cggaatgccc
     5641 gcagagcttg ttgaaaataa ggaggtcatg tcctttttcc tgccttcttt ccgatcagat
     5701 tatcgggctc ttgaacaatt tgagctttac gatctggccc agatccagtc gcctgttcat
     5761 gtctttaacg ggcttgatga taaaaagtgc atacgagatg cggaagggtg gaagaagtgg
     5821 gcaaaagaca tcacattcca tcaatttgac ggcgggcaca tgttcctgct gtcacaaacg
     5881 gaagaagtcg cagaacggat ttttgcgatc ttgaatcagc atccgatcat tcaaccgtga
     5941 tcaaaagcgg acagcttcgg ctgttccgct ttttttgtgt tgaatgccaa tttttgcatg
     6001 gtataatagt cgaaatactc aaataaaggc aggttgaaac atgcgcacgt ctcccaggat
     6061 gaaatggttt gtattgctgt ttacgtttgt tttcgccatc ggaatgaact cattcagaaa
     6121 ttcctttcaa ttttttatgc tgccaatggc agatgccttc catgccgaca ggtcgctgat
     6181 ttcggtttct gtcagcattt ttatgatcac aaccggcatc gtccagtttt ttgtcggttt
     6241 ttttatcgac cgtttcagtg tcagaaaaat tatggcgctt ggagctgtct gcatcagcgc
     6301 aagctttttg gtgcttcctt attcaccgaa tgttcatgtg ttttccgcca tttacggtgt
     6361 gcttggcgga atcggctatt cctgcgcggt cggcgtgacg acccagtact tcatcagccg
     6421 ttggtttgac acacataaag gtctggcgct tgctattttg accaatgcca actctgcggg
     6481 cctgctgctt ctctcaccca tttgggctgc agctccgtat catgccggct ggcagagtac
     6541 ctataccatt ttgggaatcg tcatggcggc tgttctgctg ccgctcctcg tctttgggat
     6601 gaagcacccg ccacatgcgc aagcggaaac tgtgaaaaaa tcttatgatt ggcgggggtt
     6661 ttggaacgtg atgaagcaat cccgcctcat tcatatcctg tacttcggcg tgtttacttg
     6721 cggatttaca atgggaatta ttgatgctca cctcgtcccg atactgaagg atgcgcatgt
     6781 ctctcatgtc aacggaatga tggccgcgtt cggggcgttt atcatcattg gcggattatt
     6841 ggcgggctgg ctgtcagatc tccttggcag cagaagcgtc atgctatcca tcttattttt
     6901 cattcggctg ctcagcctca tttgcctgct cattcccatt ctcggaattc atcacagcga
     6961 cctttggtac ttcgggttta tcctgttatt cgggctcagt tacacaggcg tgatcccgct
     7021 gaccgcggcg tcaacttcgg aaagctatca aacaggattg atcggatcgc tgctaggcat
     7081 caatttcttt atccatcagg ttgccggagc tcttagtgtg tatgcgggcg gtttgttttt
     7141 tgacatgact catggttatt tgctgattgt cgctgtgtgc atcgtgtttg tgggtttatc
     7201 ggctgtaata gagctggtgc cgtttttaga taaacagaag gcaaaagaaa cccaccattc
     7261 aatataaaag gatcagcact gtcaatgctg atccttttta aatttgagtt tttttgtttc
     7321 ggtattttta aggataatct ccttgaatct gttcatctcc tcttcggagt gaaaaaaatg
     7381 tttggggatc gcaatatatt ggctgctgga tgtattgatc cgaaagatat tcttatattc
     7441 gaaaacagct gtgatttcat tccaattgaa aatgaggtta tattttttag aacttataca
     7501 gattccttct tgattgaggg tatatgttct tttagatttc atccgttcgt tcttcttgta
     7561 tgctctggaa aacttcacat atagaagaag gaggagcagc agtgtaaaca gaacggacat
     7621 cacgataatc aacatactgt tcataaacaa gttaagcgcg tcactgccat aaacgatacg
     7681 gggccatcca ttaatgaagt taactgcagc aaatatggcg caaaacaaca gaaagtaaaa
     7741 gcatgatatt tttgcgattt gataaaaaaa gatttctctt acatccttaa aagcgatttc
     7801 tcctggaaga ttgatacttt cattagcata ttgaatcata cggtaaacct acacctctaa
     7861 ccatgttttt cctttcagtc tagcataatt tctcattttt ttgcaggcat accagggcgc
     7921 tttgtttttt tctccagatt gatattgctc cccaccacgc caatcataat acaaacagcc
     7981 ccggcaagat gataccaggc caggctttcg ttgagaatca caactcctgc aatcatcgtc
     8041 acaatggtag atacatgatt aaaagcactc attttaaatg cctcaattcg cgacagcgta
     8101 tagttagaca gaaatgaagt gacaagtgaa gacagcacgc ccaaatacac aatggcgaga
     8161 acgaagccgg gctcccggaa cggcagaaaa taagtgccga ctgttcccgc cgctccgtga
     8221 cgcacaaggg cgatggcgtt gaagacgaca aagccgatgg ctgacatgat gtaggtgagc
     8281 tcggtcagct tgaaccgctg cgtcattttt ctggcagcag tattgtacat cgctgaagac
     8341 aaagcagaca ataggatcag caaagaccct tttaagctgg ctgattccac gtcaacgcct
     8401 ttcatcacaa aaataaacat gacgccggca acggataaaa ccgtgaaccc cttttgcgtc
     8461 cacgttgggc gttcctttaa aacataagcg gcaaagacca tcgtgaaaat cggaatggct
     8521 gcctgaataa ttcccgcttc agaggaggac gagtccacaa ggccgaatgc ctgaaagctg
     8581 aaaaataacg cgggatacag cagggcgagc ggcaaaatgg caatgacgtc ctttacgcgg
     8641 attgatagct ttacccagcc gaataagatc ggtacagtgg ccgcagcaaa cgcaatggtg
     8701 aaccgatgcg ccaaaatatc aaacggctct gctgtttgca gtgcgatttt tacgaataga
     8761 aaggataaac cgataatgaa tgaatataaa atagccgcta tataagcggg ggcttgctga
     8821 tgtttaacca taatgggaag tgctccttta cctgaattgc agcgccggtc gctcccttta
     8881 ttgtatggcc gcggtcagaa cggtacaatg agaaaaacaa tgaactgtac cggtacaaaa
     8941 cagggggaga aggcatggag aaatatatga gtctagtaac gaggatagag gagatgaggc
     9001 aaagcaccgc ctatcaagaa ggagacaggc ttccatctat ccgtcagctg tccgcccgct
     9061 accaagtcag caaaagcaca gtgatccgcg cgctgcagga gctggaaaag cgccacctta
     9121 tctattctgt tccgaaaagc ggctattata ttgtgaaaaa gacagggaaa tcaaaaagcg
     9181 ggcagcctgg ccccatcgac tttgccacat ctgcgccgga tccagatgtg tttccgtatc
     9241 ttgattttca gcactgtatc aacaaagcga ttgatacata caaaaacgat ttgtttattt
     9301 atgggacgcc aaaggggctt ccatcactca tccgcgtact ccgaaagctc ttggccactc
     9361 aacaggtatt tgcggatgaa cggcatattt tcattacatc aggtgtccag caggcgttat
     9421 ccttgctttg tgccatgccg ttcccaaatg gaaaagagaa gatcgccatt gaacagccgg
     9481 gctaccattt gatggtcgaa cagcttgaga cgcttgggat ttccgccatc ggggtgaaac
     9541 gaacggaaga agggcttgat atagccgagg ttgagcggtt atttcaaaca gaatcgatta
     9601 aattttttta tacgatgccc cgcttccata acccgcttgg ctgctctttg tcagagcgtg
     9661 ataaacagga gcttgtgaga ctggcagaag cgtatgatgt ctacctcgtt gaggatgatt
     9721 acctcggtga tctggaggaa aataaaaagg cagatccgct gtacgcatat gatctgtcct
     9781 cacatgtcat ctatttgaaa agcttctcga aaatgatgtt ccccggcctt cgcgtggggg
     9841 cggctgtttt gcccgaagcg ctgactgaca cgttctatgc gtacaaaaag ctgaacgaca
     9901 tcgactgttc gatgatttct caagcggcat tggagattta cctgaaaagc ggtatgtacg
     9961 gcaggcataa ggagaaaatc agaaattctt ataaagagcg gtcgctgagg ctacatcaag
    10021 ccattcaaac acacaggcag ctgggaagcg gccgctttac gttctccagc gggcaggcac
    10081 tctgtatgca cacccatctg gtgcttcctc aggatctgcc cgcctcaaga gtgattcata
    10141 ggctgaaaaa acaaggggtg atccttgagg cgatagaccg tcattattta tcagattatc
    10201 agaaagaaaa tctattaaaa atcaatattt ccaatgtgaa aacggaagat attgagcgcg
    10261 gtgtcaagct gttgatgagc catttataaa agctcttcgt acgagaccat tgtgatatcc
    10321 tcggggaaat cagggtgtgc ggcgcataca gccattttgt agccgggatc gacctcatac
    10381 gttttgatat agcatgggga atggctgtcc ggaagctcaa tggatacttg tccgtcctga
    10441 tgcaggcgca ctgaaaagga atcaagcgga agcgataagc ctttgccttc ctgtttgata
    10501 aagctttctt tcattgacca tagatgataa aaatagtctg tctgctcgtc cttgtctttt
    10561 gctaaaaggt cgctgtactc tgtttttgaa aagaagcgct tggcgatctc aagactgatc
    10621 ggtttcgttt tttcgatatc tatgccgatt ggctgtgaat caaacgcacc aatgacccag
    10681 cggccggagt gagaaatgtt gaaatgagcg tcgggaagat cagggatgca cggcttcccg
    10741 tattcctgcg tgctaaagcg gatatcggat ttgtccaact gatactgcct gcttatgact
    10801 gagcgaacga gcacatctcc cagcagggtg cggtgagcat cttctttatg ataaaatctc
    10861 cggcatttct cccgtttttc aggtgatatg aaagtcatga accgttcatt ttcttcctgt
    10921 gaaagcgggc ggtccatata aattccgtaa atcttcattc tagatcctcc gtctgcaaaa
    10981 gattgtcaaa accatcctat catacttcca caagactcat atagaggaga aaataaaaaa
    11041 acaaagccaa ggcggctttg ttttagtgga caggcggaga tgctttcaca gcggctgtcc
    11101 gccttgccac agcataattc agcagctgga ttgactgcgg caatgaaaaa cgcagaatga
    11161 gcccggtgag gatggcggtc aaaatggtgc caaaaccgat cggcccaccc atgccccatg
    11221 ccgcaaacaa aatggttaat tccatgccgt tccgcaccca ttgcacattc cagccggttt
    11281 tttctgtaat cagcatcatc agtgaatcac gcggccccgc gccaaggcct gctgatacat
    11341 aaacaccgac gccgtaaccg atcagcacca cgcctagaga gaagacgatg atcgagcctg
    11401 tgtaggtcga gggggcaggc agaatgaaat tgaaaaaatc tataaataca ccaatgagca
    11461 ccatattcag gagggcccca attttcggcc aagctctcgt aaacaatgac gtgaatccga
    11521 cgatgagcgc tccaataatg atggaccact ggccgacggt aagcccgaag tgctgaaaca
    11581 ggctgtaatg aaatgcatcc cacggactaa tgccgagtgc ttttccttct atcgtcaggg
    11641 atacaccaaa agccaaaatg atcaaaccgg caaaataaaa tgtccagcgc agaacaagtt
    11701 cttgcttcac gtgaggtccc ttctttcgta aaaatcagtc gattgtcatt gtagcacatc
    11761 tgacagaagg gcggaatagg cgaaaggggc tcaacaaaaa aacagggcgc gggcgccctg
    11821 tttttcttat tacagcgggt tcaaaatccg gtttaagaac cgctgtgtcc gttcttcttt
    11881 tggtgcggag aaaatttgct ccggcggtcc ctgctccacg ataacgccgc cgtcgatgaa
    11941 gatgacttca tccgcaacct cctgcgcgaa cttgatttcg tgggtcacga cgaccatggt
    12001 ccagccttca ttggccaagt ccttgataac cttcagcacc tctccgacaa gctcgggatc
    12061 aagcgctgag gtcggttcgt caaacagcat gagctcaggc tgaatcgcca gtgcgcgggc
    12121 gatgccgacg cgctgctgct ggccgccgga aagctggaac ggatataaat ccattttgtc
    12181 cttcaatccg actttatcaa gaagctgaat cgcttctttt ctgacttcct ctttgttccg
    12241 tttttgcacc tgaatagggc cctccatcac gttttcgagg gctgtgcggt gcgggaacag
    12301 gtgatacgcc tgaaacacca ttccggattt tcggcgaagc tttaggatat ccgcctgttt
    12361 cacctttttg gagaaatcga tggagaaatc atcaaatgca agctctccgc gattcgggat
    12421 ctccagagcg ttcaggcagc ggagcagcgt cgttttccct gaacctgaag gcccaagtat
    12481 ggcgatgact tttccttttt caatcttcat atctatcttt tttaaaattt cattttcacc
    12541 gaatgatttg tttaatcctt taacggtaag catactcgga acctccttat ttggccacgt
    12601 agcggtcaag acgccgttcg atgacatgct ggacgagtga gagcaggaag cagataatcc
    12661 aataaataaa ggctgcttca atatagatca ctaaaatttg atcaagattc cgcgcgccga
    12721 tttcctgggc ttttctgaac agctctgcga ccagaatttg agaggcgagg gatgtatctt
    12781 taatcaggct gataaaggta ttggataatg gcgggatcga cacacgaaac gcctgcggca
    12841 aaatgacgcg gaacagcgtt ttttgatgtg tcatgccaat tgtgtagccg gcttcccatt
    12901 gccctttcgg cacggataaa atagatgccc gaatgatttc agatgcatag gcgccgacgt
    12961 ttaatgaaaa ggcgataact gcgcttggaa atggatctaa tgtgacatta aaggccggga
    13021 acagatagaa aatgatgaac aattgaacga gaagaggagt gccgcgtatt gcggatacgt
    13081 atacgctgaa cacccatctc aaaggtctca ctttcgacat tctggcaagc gccgtaatca
    13141 gcgccaggat cattccgaat ataaaggaaa gaatcgtaag gggaatcgta tagtagattc
    13201 cccctgaaag tatcggccag aatgactgct gcaccagatc ccacgggatc gccgtgccaa
    13261 gcgtcaatgc cggcagatta tttagaaaca tcttcgccga accatttttt agaaatttta
    13321 gaaagagtcc cgtcctcttt catttctttt aatgctttgt tgacttgatc aacaacctcg
    13381 ccgcttcctt tacggaacgt gaaatatgtt gactgaggat cacctgtttc aaacgcgatt
    13441 ttcacgtttt tattgccaga tgtttttaag tagttcaata cggcaagctt atcgttgtat
    13501 gtcatatcga cgcggccttg ctggatcatt tgaagggcct gcgccatgcc ttcaacgcct
    13561 tctactttag cgccggcatt tgtagctaat ttgttgtagt tgcttgtcag tgattgagct
    13621 gacgtttttc cttttacatc tgcttcagac ttaatatcgt tgttgtcttt tttcgttacg
    13681 acaacggctc ttgatgttgt gtatttatct gagaaatcat atttgtcttc acgatctgtt
    13741 tttccgactt ggttggcaac aacgtcaaac cgtttggaat tcaggccggc aaacatactg
    13801 tcccattgtg tttccttaaa gtcgacttta agcccgaggc gttttgcgac ttctgtgata
    13861 acttcgacat catagccagt cagtttatca gtgtctttgt cgtggtaagt gaacggctca
    13921 tatgttcctt ccgttccgac tgtgagcaca ccttttttct taattgaagc ccaaagatcg
    13981 ccatctttgg cattatcttt tgactgattg tcatttcctg ctccgcaagc tgcaagagct
    14041 gcaatactta cgaccatgaa taaagccaat aatgcttttt tcatcttatt ccccactttt
    14101 ctggttgatt ttattgaaat aaaaaaatag cttacaaatc taaaggataa ctttttttta
    14161 gtatgagtca agtaattggt tttcataagg cgaaatcttt taaaataaat ccaaaaattg
    14221 ctgtgccggt ttaggcaaat aactgtccgt tctccacatg acagccggtg tcataatgaa
    14281 gggattattt tcgatatgga cggtgtgaac gtgatttctc atatgaacgg gaatcattgt
    14341 gacaggcaaa atagacgcgc cgaatccgga tgacacgagg ctgagcaaag ttgcagagtc
    14401 gtggcattca caaacaatgc gcggctccag gttcaaacga tgaaattcat tcatgacctg
    14461 attatagacg ccttttccgt tgacaggccg cagcaggatc agcggaaatg aaggaatgtc
    14521 ctccatctta atggtgtctc cgcacggata tccggcttca tctgaaagca cgagcacaca
    14581 tggaatgtca tcaagctgtt tgaattgtac tgtgtcactt ttgatcagtg ttgtcgtgac
    14641 cgccgcatcg atttgccggc tttccagcag ctccaacagt gtcgcgggct cattttccca
    14701 aatattaaag gtgagatggg ggtatctctc tttgatctgt gttacttttt caagcatcag
    14761 agccgcgcaa taaattgttg atcccacggc aagtgtgccg gctacttcct ccttcagctc
    14821 ctgtacctca atgactgcat cttcaaacct atgcagaatc tcttttgctc tttttagaaa
    14881 aacagctcct tcatatgtaa gagtcatttg ttttttcttg ttccggtcga acagaacaac
    14941 accaagctcg tcctccagct gtttgagctg cctgcttaaa ggcggctgcg ccatgtgaag
    15001 ctttttggct gcggacgtaa ttttctgttc ttgggcaatg gtaatgaaat atcgaagctg
    15061 gcgaatgtcc aaaagaaagc gcctccttat catacctttt aggtatgaaa tatagattta
    15121 atagatattt ttcatatgga tatatcagga gtatgattga aatgaaagca gaattcaagc
    15181 gtaaaggagg gggcaaagtg aaactcgttg tcggaatgac aggggcaaca ggggccattt
    15241 tcggggtcag gctgctgcag tggctgaagg ccgccggagt ggaaacccat ctcgttgtgt
    15301 ctccttgggc aaacgtcacg atcaaacacg aaacaggcta taccttacaa gaagtagaac
    15361 aactggccac atacacttac tcacataagg atcaggcggc agccatttca agcgggtcgt
    15421 ttgataccga tggaatgatt gttgcgccgt gcagcatgaa gtctctcgca agcattcgca
    15481 ccggaatggc ggataatctg ctgacacgtg cggcggatgt catgctcaag gagagaaaaa
    15541 aactcgtcct cttaacgaga gagacgcctt tgaaccaaat tcatctcgaa aatatgctag
    15601 cgcttacgaa aatgggcacc atcattcttc ctccgatgcc ggcattttat aatcagccga
    15661 gcagcttaga ggaaatggtt gaccatattg tttttagaac gttggaccaa ttcggcattc
    15721 ggcttcctga agcgaagcgc tggaatggga ttgaaaaaca aaaaggagga gcttgatcat
    15781 ggcttatcaa gatttcagag aatttctcgc agcccttgaa aaagaaggac agctgcttac
    15841 agtgaatgaa gaggtaaagc cggaaccgga tttaggggcc gccgcacggg cagccagcaa
    15901 tcttggcgat aaaagccccg cgctcttatt taacaacatt tacggctatc ataacgcgca
    15961 aattgcgatg aatgtcatcg gctcttggcc aaaccatgca atgatgctgg gcatgccgaa
    16021 agacacaccg gtaaaagaac agttttttga attcgcaaag cgttatgacc agtttccgat
    16081 gccggtcaaa cgtgaggaaa cagcgccatt tcatgaaaat gaaatcacag aagatatcaa
    16141 tttgttcgat atactgcctc ttttcagaat taaccaagga gacggcggtt actatttaga
    16201 caaagcatgt gtcatttccc gcgatcttga agaccctgac aacttcggca aacaaaacgt
    16261 cggcatttac agaatgcagg tcaaaggaaa agaccgtctc ggcattcagc ctgtcccgca
    16321 gcacgatatt gcaatccatc tgcgccaagc tgaagaacgc ggcatcaatc ttccggtcac
    16381 cattgcgctc ggctgtgagc cggtcattac aacggcggca tcgactccgc ttctctatga
    16441 tcaatcagaa tacgaaatgg caggcgcgat tcaaggcgaa ccatatcgca tcgtcaaatc
    16501 aaagctgtct gatcttgatg ttccgtgggg cgctgaagtg gtgcttgaag gtgagattat
    16561 tgccggagag cgcgaatatg aagggccgtt cggtgaattc acaggccatt attccggcgg
    16621 acgcagcatg ccgattatca aaattaaacg cgtctatcac agaaacaatc cgatctttga
    16681 acatttatac ttaggcatgc cttggacaga atgcgattac atgatcggca ttaacacatg
    16741 cgtgccgctt tatcagcagt taaaagaagc gtacccgaac gaaattgtgg cagtgaacgc
    16801 catgtacaca cacggtttaa tcgcgattgt ttccacaaaa acccgctatg gcgggtttgc
    16861 gaaagcggtc ggcatgcgcg cactcacaac gccgcacgga ctcggctact gcaaaatggt
    16921 cattgtcgtt gatgaggatg tcgatccatt caaccttccg caggtcatgt gggcgctttc
    16981 gaccaaaatg catccgaaac acgatgcggt catcattccg gacttatctg tcctgccgct
    17041 tgatccggga tccaatccat caggaatcac tcacaaaatg attcttgacg ccactacacc
    17101 ggttgcgccg gaaacaagag gccattattc acagccgctt gattctccgc taacaacgaa
    17161 agaatgggaa caaaaactaa tggacttaat gaataaataa ggaaaggatg ttcgaaatgc
    17221 atacatgtcc tcgatgcgac tcaaaaaagg gagaagtcat gagcaaatcg cctgtagaag
    17281 gcgcatggga agtttatcag tgccaaacat gcttttttac atggagatcc tgtgaaccgg
    17341 aaagcattac gaatcccgaa aaatacaatc cagcgtttaa aattgatcca aaggaaacag
    17401 aaacagcaat tgaagttccg gcggtgccgg aacgaaaggc ttgatccgcg tgaacagttt
    17461 gtcagaccgt ctctttgagc tgcttgacgg gagatgcctg agtgagaagc agcatgaggc
    17521 cttcgttctg caaacagtat cagaggatgg ctggccgcat gccgctatga tcagtgcagg
    17581 tgaaattatc gcgctgagcc gaactgatat ccgaatcgct ctgtggaaaa acacaatgac
    17641 ttcggccaac atccttcgca caggaaaagc acagttcacg gcgtggtgga agggagcggc
    17701 ctattatgta aagcttgaat gcgcgccttt accgcctttg aaagatgctg aatatgatag
    17761 agaccgtttt tcctgccgca tcgtttcagt gaaggaggac gttgcgaaat acgctgattt
    17821 gacttcaggt gtccgtatac agcttcacag cgctgaagag gtgctgagca gatgggaaaa
    17881 gaccctggaa gatttaaagc ggtaatatcg atagcctgac gccatgcgtc aggctttttt
    17941 tatataatga aaacaaaggg ggcgtgagaa atggaacgtg cggggatctg tcactcggac
    18001 ggctttgatt tagcttatcg aattgagggc gagggcgcac ccatccttgt gatcgggagt
    18061 gcggtttact acccgcgcct tttttcctca gatatcaaac agaaatatca atgggtcttt
    18121 gtcgaccata ggggatttgc taagcttaag cgagggcttc gtgcggagga ttcgaggctt
    18181 gatgccgtct tggctgatat cgaaaggatg agaacatttc ttcagtttga ggatattatt
    18241 atcctggggc attccgggca tgcttttatg gctttggaat atgccaggac atatcctgaa
    18301 catgtccgga aggtggcgct cttcaatact gcgcctgata acagtgaaga aagacagcga
    18361 aaaagcgaat catttttcat ggaaacagcc agccttgaga gaaagaaacg ctttgaaaaa
    18421 gatatcgcga atttgccgca ggacattgaa aaagatcctg aaagacgctt cgtgcatatg
    18481 tgtattcgcg ctgaagcgaa aagcttttat caagagcggc cgcatgcagc tgccttatgg
    18541 gatggcgtat tcacgaatat gccgatcatt gatgaattat ggggcaatac atttgcccgg
    18601 attgatcttc ttcagcggtt agctgatgtt cgtatgccgg tgtatatcgg attagggaga
    18661 tatgattatt tggttgcacc cgtttcgcta tgggatgctg ttgacggttt atatccccat
    18721 gtggataagg ttatttttga aaagagcggc catcagccga tgctggaaga accggaagcc
    18781 tttgatcaaa gcttcagcaa atggctggat caataaaaaa acagcccgca gatcaaaatc
    18841 cgcgggctgt ttctgattat aagacccctt tcatcgcgcg tttgatcatc ggcgagagca
    18901 gcaggagaat gccgccaaga acgatagaaa tcaaaccgat ggtgccgaag tacattgttt
    18961 caggaatttt atcaaacaat ccggctactt gggcattgat cgcttgggct gctgcgttcg
    19021 tcagaaacca catactcatt gtctgtgcag agaaggcagc tggtgccagt ttcgttgtca
    19081 cggataaacc gactggagac aggcacagct ctccaagcac gacaagcagg aagctgagaa
    19141 cgagccaaag cgggcttacg agtgcttctt ttccttgcat agcagggaat accataatga
    19201 taaatgacaa tccggctaaa ataattccga ttgagaattt aactggtgta gacggctggc
    19261 gtttgccaag cttcatccag agccatgcga atattggcgc aaaaatgacg acaaacaatg
    19321 gatttaatga ttggaaccat gatgattgaa gttcgaatcc gcccaatgaa agtcttattc
    19381 gttcatcagc gtataccgca agaatggtcg ctccctgttc ctgaatggcc cagaacatga
    19441 cagcaccgat aaacaaagga atgtaagcgg caagacggga tttttctgtg ctgtccgctt
    19501 ttttgcttgt aaacatgatg atgaaataaa tgacaggaat caaaataccg agaatactta
    19561 caaggtcgat aaaacgattg atcgtcagca cgcctgtttg tacagagatc atcactgcga
    19621 tcgccacgat gataacaccg attccggtgc caatcgcaga ttttttagac agcggattcg
    19681 gcacattgga acctgcaagc ccgaggtttt tctttcttgt caaagcaaat acgataagtc
    19741 cgagaagcat tccgaccgcg gcagctccga atccgagatg atagttgtac ttctgtccga
    19801 gtgttccgac aattaacggc gcgagtaaac caccgaggtt aatccccatg tagaaaatac
    19861 tgaaacctga gtcgcggcgc gggtcttctt tcgtgtaaag atccccaacc acgcttgaaa
    19921 cgtttggttt taataagcct gttccgacaa tgataagcac catgctgata tagaatgcta
    19981 tcgaactgcc cggataggcg agtgcaatgt ggccgaacat aatgaatatg ccgccgtaaa
    20041 acacggtgtt tgcggtaccg aatacccggt cagcgagcca tccgccaata atggtggaca
    20101 tgtatacgag tgatccgtaa atcgacataa tggcaaccgc agtgcccttg tcaaagccga
    20161 gccctccgtt taccgtctct gtatacaaat agtaaagtaa gattgctctc attccatagt
    20221 aagagaaacg ctcccaaaat tcggtgaaaa atagtgtaaa tagtcctcgc gggtgaccaa
    20281 agaacccttt ttgcgggacg cttttaatga tactttcgtt atcaatcgaa gccatgtcag
    20341 ccaaaccctt tctaaaaaaa gtgtattata aaaatcatat tcttatataa tacttgtgtc
    20401 aatataattt atactcattt caaatagttc catattggaa aaattataaa tacctaaaaa
    20461 tagtgatttc ctcctaattt ttaaactttt tatcgtgaga ttttcttaca caactattcc
    20521 tttatatttt tttaataaaa ttttagagaa atgtacaagc agatcgggcc tttgtgagta
    20581 acatgatagt aatcatagag aaggaggctc gcaattggct gaattcatat taaatgcagc
    20641 ggatttcggt gttcctggag atggtaaaac ggattcgaca gaacggatta atcagtgcct
    20701 cagtacagct gtatcgaaag gctatcatac tgtctggttt ccaaagggaa catatttaat
    20761 agacgcaacg cttggcggag atcttaatca gaggtttcga aacgcgggga tcattgttcc
    20821 cggcaacctt gagattatga tggaccccga atgtatcatg aaagtgatcc cgaatagttc
    20881 gtggggttat tccgcatttt atgtgggcaa gcaagagaat ataaccattt ccgggggaca
    20941 aattatcggc gaacgggatg agcatacgta tgcctcggca gggataaggt caacccatga
    21001 atggggcttt ggcatatgta ttgaaggatg ctcgaatgtt gtcattgatg atgtgaaaat
    21061 ttctgatttt accggcgatg ggatcatagt cagcccaagg ggattaaaga ccaatcaaga
    21121 ttatcgaacg tcagagcaaa ttatcatccg ccgctgtgag gttcggcggt cgaggagaaa
    21181 taacatttcc attaccggat gtgacatggt cacggtggag gaatgcttga ttgaagatgc
    21241 cggaacgggg aatggaacag cgccgaaatt cggaattgac attgaaggat atggcgaagg
    21301 tgatgttgat tatgaggaac cgattaatgt atcaattcgc aataaccact ttgttggaaa
    21361 cgtttcaagt tctgtgacca attttaacgg gtatggcatt ttaatagaag gaaatcactc
    21421 tgacaataca atcagctacg gatatgggac gcaaacagtg atcaagggca atattctgag
    21481 acgccctgaa gacgcggcgg ctgcgccaag agtcgggata accggactcg gtgtatcaca
    21541 aggaaaagag accagtgatg cagtgatcgc tggcaacctc attaccggat tttcaactgg
    21601 aattgatgtc agaggaaaga gcgttcttgt gacgaacaac aaaatcagca actttgaaaa
    21661 cacagggata ttggtttatc agtcttccga tgtaaaggta gacggaaacc aaattcaaaa
    21721 cggactgtct gaaacaaggc gcagcatcgg tcttcgcgca gtgctgtcag atgacatcgc
    21781 ttttctgaat aactgtctca ttcaagtcgt tgacggtgtg aacgtttccg gcggaaatat
    21841 gatcattaaa gataatctcc tgagaaaatt cagccggggc atttggattg ctcaagggaa
    21901 cgcggtgatt gaagggaata cactgaatcc tgacgcgttt gaagcagtgc cggaatcata
    21961 ttctgtttcc gtcacaaaca atgccggcgc catcatcaaa aacaatacat ttaaagagtt
    22021 caaaaattac cccatttatt gctccacaag tgcgaaaacc tcaattatcg gcaaccactt
    22081 agagagatct ccgcttttgg tcaccatcta tatcagcgcc ggtgtgcatg agatttttga
    22141 taataccatt tcagtcaaca gaacagccgg gaatccgatt gtgatttata tcaatggctc
    22201 tgcaggctct atcgtctcag gaaacaccat caataacctc tccgcgggca ctgcgacagc
    22261 tattcaaaca aacacctcaa ccaactccaa aatcatcggc aaccgcattt ttaaagggac
    22321 aatcaacaaa cacagcagtg atacaataga cggcaatttt atcgtctgaa aaaagcgccc
    22381 cctctagggg ttcttttttt tcgatttata gatcacgtac atttctctca caagtactaa
    22441 cacaaaaaat aaaatcacga cccattcagc aaatgttgtc atcttaaagc tggacatatt
    22501 gttataaacg gcttttgtta aactgaaccc ttgaagcatg tccatcaata cagaaatagc
    22561 taataaacaa attaatatga ctccggtcac gcccaatatc ttcatgcttc atcatcctcc
    22621 gcttttagtg tctatcgttg gcggagaagt tataccgcat ctaaacctaa tgcataatct
    22681 caattttaaa aggaagaata tgagaaaacg acaaggaaag gtatttgtgt atgcctttat
    22741 tttctaagcg aaagaacaat acaagttcga aagacaagcg aaatacagaa gaaaagaatc
    22801 aggaacagca gcaagaaaaa gaaaggccgg ttctcatttc tccaagtttg gcaaagaata
    22861 tagcggaaac gaaaaaggaa gtcggaagca gctctgacgt catcattcgc gagattaaaa
    22921 tcggggagca ggatcatgtc catctagctg ttatctatat tgctgggctg gtcgataata
    22981 acacgatcca tgagtcgtta attgacccat tggtacagga tgagtctatc cagaatactc
    23041 atgcgatcca gcaaattctt gaaaaaacgc tcccgctggg cggggtgaaa gcggaaaaga
    23101 gctgggacaa gcttttttcc gagttaatgc tcggcaatgc gctcattttt gctgatggcc
    23161 atgatgaagc tttgatttgc agcactcaag ggggagagca gcgctccatc caagagccga
    23221 gcacccaggt gtcattccgc ggcccgcgcc aagggtttac agagtctctg caaaccaata
    23281 tttccatgat ccggcgatac attaaaaatc cgaatttatg ggttgaaaaa atgaaaaaag
    23341 gttctgttac gaatacggat atcgctctca tgtacattca aggaatatgc gatgaaaagg
    23401 tgctgaagga agtgaaacag cgcctggaaa aaatagatat tgacagtatt ttggaatctg
    23461 gatatattga gcagctgatt gaagatgaaa cctttacgac gtttccgact atgtatcata
    23521 cagaacgccc tgatgttgta gcgggtaatc tgttagaagg aagattcgcg attattgtcg
    23581 acggaacacc gtttgtgctt attgccccgg ccttatttgt ccagtttttt cagtctgttg
    23641 aggattatta ttcgcgtttt gacattgcga caagcataag aattcttcgt gttttagtct
    23701 ttttcatttc gcttgtggct ccggctgtat acgtggcagc cacgacgttt catcaagaaa
    23761 tgataccgac tcagctgtta gtggtcattg cggcccagcg ggaaattgtc ccgtttccgg
    23821 ctgttgtgga ggcgttgacg atggaggttg cttttgagat tctgagggaa gcgggagtca
    23881 ggctgccccg ggttgtcggc tcggcagtgt caatcgtagg cgcgctcgta atcggccagg
    23941 ctgccgtaca ggctggtatc gtctctccgg caatggtgat tatcgtggca ctcaccgcga
    24001 ttgcgagctt cgcaacaccg gcgtttgcaa tggcgatttc agcccggctt attcggttta
    24061 tctttattat tgcctcagct gttatgggtt tttacgggct gattttaggg atcattatga
    24121 tgtttgtcca cttatgcagt cttcgttcat tcggcgttcc atatatgtcg ccgcttgcac
    24181 ctttttcttc acaaggcgta aaggacgcgc ttttccgggt tccgtggtgg gccgatgaaa
    24241 aaaggccgga atcggtcagc aaggaagata aggtgcggca ggggaaagat caacgcccag
    24301 agccggccgc ttcacgagga atggtgaaca aagatttgga agaaggggat cagaatggta
    24361 cgtaaatgtc tattagccgt tctcatgctt ttgagcgtca ttgtgctgcc cggctgctgg
    24421 gataagcggg agctgacgga tcttgcgatt atctcggcga ttggcatcga tcggacaaac
    24481 gacagcaact acgtgctgca tcttcaaatt atcaatccag gaaatgttgc cggcggcctt
    24541 cagggaggcg gtgctggaga caggccgcct gtatctgtct attcgattga aggtaacaat
    24601 ataacggaag cactcagaaa agcctccatg aaggtatcac ggcggcttta ttttgcccat
    24661 accaatctag tcgtgatcaa tgaaaagctg gcaaaagaag aaggtttgga ttttgtatta
    24721 gataatcttg accgggacac agaattcagg acaacagcaa cattcgtcgt tgcccataaa
    24781 acaaaagcag aaaatattgt gaaaatcttg acgccgattg ataaaattcc gtcaaataaa
    24841 gtcaataaaa cactcgattt cacggaggca caatacgggc gggtggtcaa aatcaatatt
    24901 caggacgttt tgaaaacact tgccgccaac actatggcac cggtcatccc cggatatatg
    24961 atgattggtg acgataaaaa aggagtcagc atggaaaaca cgcaggcgac tgacccgaaa
    25021 gccattcttc aggcagatgg tttggcggtt tttgataagg caggatattt aaagtattgg
    25081 ctggaagatg atgaaagcgt gggggcagtc tggcttatga ataagatcca gcatacgttt
    25141 attaatgctg actggggcaa gacgaaggat gcggtcagct tgc
//
