LOCUS       NZ_JAANHO010000006     26378 bp    DNA     linear   CON 06-NOV-2024
DEFINITION  Bacillus sp. EKM208B 101228_scaffold6, whole genome shotgun
            sequence.
ACCESSION   NZ_JAANHO010000006
VERSION     NZ_JAANHO010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. EKM208B
  ORGANISM  Bacillus sp. EKM208B
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Bacillus.
REFERENCE   1  (bases 1 to 290422)
  AUTHORS   Khalaf,E.M. and Raizada,M.N.
  TITLE     Genome assembly of Bacillus sp. EKM208B
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 290422)
  AUTHORS   Khalaf,E.M. and Raizada,M.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAR-2020) Plant Agriculture, University of Guelph, 50
            Stone Road, East, Guelph, On N1G 2W1, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: EvoCAT (Evogene Clustering & Assembly Toolbox) v.
            December-2019
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 87.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011800725.1-RS_2024_11_06
            Annotation Date                   :: 11/06/2024 06:22:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,002
            CDSs (total)                      :: 3,928
            Genes (coding)                    :: 3,848
            CDSs (with protein)               :: 3,848
            Genes (RNA)                       :: 74
            rRNAs                             :: 3, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2, 3, 1 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 39 of 80
            Pseudo Genes (incomplete)         :: 55 of 80
            Pseudo Genes (internal stop)      :: 8 of 80
            Pseudo Genes (multiple problems)  :: 20 of 80
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:46:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 120282
            Orig. end                         :: 146660
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAANHO010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26378
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..26378
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26378
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16378](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16378
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(4..19)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
     misc_feature    472..488
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    768..782
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    892..910
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.66"
                     /tool="antismash"
     misc_feature    complement(989..1002)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.01"
                     /tool="antismash"
     gene            1098..2132
                     /gene="cggR"
                     /locus_tag="G9F75_RS12520"
                     /old_locus_tag="G9F75_12450"
     CDS             1098..2132
                     /codon_start=1
                     /gene="cggR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151607.1"
                     /locus_tag="G9F75_RS12520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12450"
                     /product="gapA transcriptional regulator CggR"
                     /protein_id="WP_003151607.1"
                     /transl_table=11
                     /translation="MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLAASLG
                     LTERVLRSEVQFLKEQNLIDIKTNGMTMTEEGYSLLSILEDTMKDVLGLTLLEKTLKER
                     LNLKDAIIVSGDSDQSPWVKKELGRAAVACMKKRFSGKNIVAVTGGTTIEAVADMMTPD
                     SKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEP
                     SVKEVLHTIKSASMLVHGIGEARTMAERRNTPLEDLKKIDDNHAVTEAFGYYFNADGEV
                     VHKVHSVGMQLDDLDAIPDIIAVAGGSSKAEAIEAYFKKQRNTVLVTDEGAAKKLLRDN
                     SPSI"
     gene            2166..3173
                     /gene="gap"
                     /locus_tag="G9F75_RS12525"
                     /old_locus_tag="G9F75_12455"
     CDS             2166..3173
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391274.1"
                     /locus_tag="G9F75_RS12525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12455"
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_003151611.1"
                     /transl_table=11
                     /translation="MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLL
                     QYDSVHGKLDAEVKVDGSNLVVNGKTIEVSAERDPAKLSWGKQGVEIVVESTGFFTKRA
                     DAAKHLEAGAKKVIISAPANEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPFAKV
                     LNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAENIIPTSTGAAKAVSLVLPE
                     LKGKLNGGAMRVPTPNVSLVDLVAELNKDVTAEDVNAALKEAAEGDLKGILGYSEEPLV
                     SGDYNGNANSSTIDALSTMVMEGSMVKVISWYDNESGYSNRVVDLAAYIAKQGL"
     CDS             3200..3430
                     /gene="allorf_123482_123712"
                     /locus_tag="allorf_123482_123712"
                     /protein_id="allorf_123482_123712"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGLLQNVRVLKFP
                     RHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
     CDS_motif       3200..3304
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /locus_tag="allorf_123482_123712_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3305..3430
                     /prepeptide="core"
                     /locus_tag="allorf_123482_123712_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="4707.5"
                     /monoisotopic_mass="4704.6"
                     /core_sequence="LQNVRVLKFPRHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /leader_location="[3199:3304](+)"
                     /alternative_weights="4725.5"
     misc_feature    3243..3252
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.98"
                     /tool="antismash"
     gene            3495..4679
                     /locus_tag="G9F75_RS12530"
                     /old_locus_tag="G9F75_12460"
     CDS             3495..4679
                     /EC_number="2.7.2.3"
                     /codon_start=1
                     /function="3-phosphoglycerate kinase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391273.1"
                     /locus_tag="G9F75_RS12530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12460"
                     /product="phosphoglycerate kinase"
                     /protein_id="WP_014418909.1"
                     /transl_table=11
                     /translation="MNKKTVKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTIK
                     HLADQGAKVLLASHLGRPKGEVVEELRLTPVAARLGELLGKEVKKADEAYGDAVKAQIS
                     DMKDGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTAGIAEHL
                     PAVAGFLMEKELDVLGKAVTNPERPFTAIIGGAKVKDKIGVIESLLDKVDNLIIGGGLA
                     YTFVKALGYEVGKSLLEEDKIELAKSFMDRAKEKGVTFYMPEDVLVADDFSNDANVQIV
                     PISEIPSDLEAIDIGTKTRETYAEVIKNSKLVVWNGPMGVFEIDLFAQGTKAVAEALAE
                     ANDTYSVIGGGDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAALNDK"
     gene            4705..5466
                     /gene="tpiA"
                     /locus_tag="G9F75_RS12535"
                     /old_locus_tag="G9F75_12465"
     CDS             4705..5466
                     /EC_number="5.3.1.1"
                     /GO_function="GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391272.1"
                     /locus_tag="G9F75_RS12535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12465"
                     /product="triose-phosphate isomerase"
                     /protein_id="WP_003151618.1"
                     /transl_table=11
                     /translation="MRKPIIAGNWKMNKTLGEAVSFVEEVKSSIPAADKAEAVVCAPAL
                     FLEKLTSAVKGTDLKVGAQNMHFEENGAFTGEISPVALKDLGVDYCVIGHSERREMFAE
                     TDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNDLVADQVKKGLAGLSEEQVAASV
                     IAYEPIWAIGTGKSSTAKDANDVCAHIRKVVAESFSQETADKLRIQYGGSVKPANIKEY
                     MAESDIDGALVGGASLEPQSFVQLLEEGQYE"
     gene            5459..6994
                     /gene="gpmI"
                     /locus_tag="G9F75_RS12540"
                     /old_locus_tag="G9F75_12470"
     CDS             5459..6994
                     /EC_number="5.4.2.12"
                     /codon_start=1
                     /gene="gpmI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391271.1"
                     /locus_tag="G9F75_RS12540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12470"
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="WP_003151620.1"
                     /transl_table=11
                     /translation="MSKKPAALIILDGFGLRNETVGNAVAQAKKPNFDRYWNQYPHQTL
                     TASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAIKNA
                     KDNDKALHLFGLLSDGGVHSHINHLFALLKLAKSEGLTKVYIHGFLDGRDVGPQTAKTY
                     IQQLNEQIEEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSAMDVVDD
                     SYANGIHDEFVIPSVITKENGEPVAKIHDGDSVIFYNFRPDRAIQISNTFTNKDFRDFD
                     RGENHPKNLYFVCLTHFSESVDGYVAFKPVNLDNTVGEVLAQHGLKQLRIAETEKYPHV
                     TFFMSGGREEEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIAADKHDAIILNF
                     ANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAIIAKGGHAIITADHGNADILITETGEP
                     HTAHTTNPVPVIVTKEGVTLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK"
     gene            7022..8314
                     /gene="eno"
                     /locus_tag="G9F75_RS12545"
                     /old_locus_tag="G9F75_12475"
     CDS             7022..8314
                     /EC_number="4.2.1.11"
                     /GO_component="GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391270.1"
                     /locus_tag="G9F75_RS12545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12475"
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_007409956.1"
                     /transl_table=11
                     /translation="MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGE
                     YEAVELRDGDKDRYLGKGVLTAVNNVNEIISPELLGFDVTEQNAIDQLLIELDGTENKG
                     KLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ
                     EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGMNTAVGDEGGFAPNLGSNEEALQTI
                     VEAIEKAGFKPGEEVKLAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEEMVSKY
                     PIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIKNGVGNSILIKV
                     NQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDR
                     VAKYNQLLRIEDQLAETAQYHGINSFYNLNK"
     misc_feature    8624..8639
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.73"
                     /tool="antismash"
     misc_feature    complement(9402..9414)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    complement(9427..9440)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.53"
                     /tool="antismash"
     gene            9698..9928
                     /locus_tag="G9F75_RS12550"
                     /old_locus_tag="G9F75_12480"
     CDS             9698..9928
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="G9F75_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12480"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_021495220.1"
                     /sec_met_domain="mature_ha (E-value: 3.7e-08, bitscore:
                     27.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGAFNTWNT
                     TTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
     CDS_motif       9698..9814
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /locus_tag="G9F75_RS12550_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9815..9928
                     /prepeptide="core"
                     /locus_tag="G9F75_RS12550_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3669.1"
                     /monoisotopic_mass="3666.9"
                     /core_sequence="FNTWNTTTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /leader_location="[9697:9814](+)"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
                     /alternative_weights="3777.2"
                     /alternative_weights="3795.3"
     gene            10001..13087
                     /locus_tag="G9F75_RS12555"
                     /old_locus_tag="G9F75_12485"
     CDS             10001..13087
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="G9F75_RS12555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12485"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_021495219.1"
                     /sec_met_domain="DUF4135 (E-value: 8.3e-98, bitscore:
                     322.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.7e-69, bitscore:
                     226.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNKYNLQYWMKMFPEVNNKDELQKIFLNVSGKTIQSLIRDDTN
                     IEQNKSIIDIDRVLDHKKSDFLVRNSEEFLEHNPFFHFFSPFLNCKIEEFLVKVRIEDA
                     VDNEDEFVKKVIKHIMDLMFEKAFRVLVLEVNIARLEGNLEGTTPEERLNHFLVVSLND
                     ESFLKSVYKEYEVLTSLLCVTIDDYFTYVMEIIKNTKREISSLNSKFNSDNDLGAITNI
                     TTGLGDTHQKGKSVSTIYFKSGKKIIYKPRDLTLEQGFQEVLYWLGEKNIPGILNFKRV
                     QIHTVNDSGWMEHIDYKSCFNKNEANDFYTRSGNLLCLLYLLNAVDFHHENLIAHGSFP
                     VLVDLESLFHARLKVDQIDKKSAVVKATELVDNSVQSISLLPTKISKRVGDKDISLDIG
                     GLAAYKEQLSPHKSLVIENAGTDTIKILRKNTFIKPQLNNPSIKTGSYLYSENYTGQIK
                     DGFASLYSWVMLNKDEFWDKISQTFKETNSRFIFRPTYLYTQLLRISSHPDFMRDTYRR
                     KIILHRIGIDYIQEYKDILNSEYKDLLTGDVPFFRSSIEHEHLIDSRGKRIHSILEEPP
                     IKTVKQKIFNLSKEDLKRQIDFIEMSYISNEKRLKEVTDIKFSKAASLNKIKSENWIDE
                     ATQIGEFIVENSVCGINKKQKDRMWIGPSLEGIEEDIWNANVLGFDIYNGNSGIALFLG
                     YLGEILNRKDFKQAAIETMRPIQKFISEIKEDHPYLIGAFQGISGYFYTLNKLSNLFGD
                     SELRKTSLENIGVLSKLGKFDKVYDLIGGSLGSLAVMLSIIPDITEENNKKEILKISHT
                     HCEHILSVAKNFEEQISWPGKFSAAYSGFSHGNSGFIAYLYKYFKLTNDEKLLEVIQRA
                     LRFERRLYSEDHNNWYTTENKDKLANGWCHGAPGILLSKLILKDNGFEDEYIEKEISTA
                     IDSSIRNGIGNNPTYCHGDLGVLSILNYASDLTNNINLKNRCLRTYQDLFENVLTKKWR
                     KRDLVCTRSYSLMIGLSGIGYSMIKNYAPEIVPNFLWLE"
     gene            13137..13346
                     /locus_tag="G9F75_RS12560"
                     /old_locus_tag="G9F75_12490"
     CDS             13137..13346
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="G9F75_RS12560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12490"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_021495218.1"
                     /transl_table=11
                     /translation="MKKDMVKKVSGFIEEDELISLANGDNATGGATPATVVLTATIGLT
                     GTTFTVTLSAASCPTSACTKQCNK"
     CDS_motif       13137..13226
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDMVKKVSGFIEEDELISLANGDNATGG"
                     /locus_tag="G9F75_RS12560_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13227..13346
                     /prepeptide="core"
                     /locus_tag="G9F75_RS12560_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="3579.1"
                     /monoisotopic_mass="3576.9"
                     /core_sequence="ATPATVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDMVKKVSGFIEEDELISLANGDNATGG"
                     /leader_location="[13136:13226](+)"
                     /alternative_weights="3597.1"
                     /alternative_weights="3615.2"
                     /alternative_weights="3633.2"
                     /alternative_weights="3651.2"
                     /alternative_weights="3669.2"
                     /alternative_weights="3687.2"
                     /alternative_weights="3705.3"
                     /alternative_weights="3723.3"
                     /alternative_weights="3741.3"
                     /alternative_weights="3759.3"
                     /alternative_weights="3777.3"
     gene            13415..16378
                     /locus_tag="G9F75_RS12565"
                     /old_locus_tag="G9F75_12495"
     CDS             13415..16378
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="G9F75_RS12565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12495"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_021495217.1"
                     /sec_met_domain="DUF4135 (E-value: 1e-88, bitscore: 292.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.6e-61, bitscore:
                     199.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISYENNNFIRDAVINFSSPTNEVEKLRIKNKDYFGNFYTFFLD
                     FYQQKLVNTLENASKENNLKLNKHKIISSALEAFSQELIQLCIRTLIVDINERKENGLL
                     EGKDSRLRYKNYNNLIFKSEYVAGILNKYPVLTYLISSRISNKILYLKEVLENLRKNRQ
                     DIYRELKIEFDEVSNIYFSSGDTHNGGKNVLIIETNQGKIVYKPHSLSPDILFNSIVDY
                     VNNSDKILKKIYKIRTLNYKDYGYQEFIDYKECETSEKLNFYFYRVGVSLSIFHIIGCD
                     DLHHENLIAHGEYPVVIDLETLIKNNSMYKPRNNNLIDNFHEDINYSVLGTMLLPLNLQ
                     TSIFDFDLGGISNDENQTSEIWKSYIIDFEGTDEIQLTKKSVIMNSTQNRAAYNGKAAD
                     PKDYIEEILKGFTDCYNFVLENKSGFYDLVKTVGSSNLEVRQVLRATSIYARFLEASTH
                     PNYLSSFEERKELFKKINIAEGVTDKFSKKNLNELESLMCNDVPYFSTMYNSLDLICNK
                     STSIVNFFRECLLDVVLNKIKSISKTSLKKQQYYIRMSLTTTIKDSWKRTNKHNKKYRP
                     KLFGNNNKNYLECATEIGDLFLETAIWNNDRSKCTWVTPIISENNKVKLGPLNFNLYEG
                     GGVILFLALLGKETGNKEYFDLAFAGMRGIEELFLSDDKMDGRLSLFTGIGSLAYIYYH
                     LYTYTNDYKYYEKFKKYINKINEMNISGDIPLDIVGGVSSLIVFLLNLYKETKLDILNS
                     VCCKLGNTLYQCLEKNGKYNYLTGLSHGYSGFTWALCYLGHITKDEKYTTLGKELLKRE
                     NKFFDLNTSNWKDLREGEGNSDPVYWCHGAGGIALSRAFLKNLLKNKENVVDKEVDKEV
                     DKEVDKDLNCAISKLLSDGFKKTTDHSLCHGIFGNIDILLKLSELLNDIDLQEVAFKEA
                     QNAINYIRNKGFIPGLQDHFDLNTFMLGLGGVGYSLLRLHNPVNPSLLAMEVRSYNE"
     gene            16375..18540
                     /locus_tag="G9F75_RS12570"
                     /old_locus_tag="G9F75_12500"
     CDS             16375..18540
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="G9F75_RS12570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12500"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_021495216.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.7e-38, bitscore:
                     124.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKKKKRVPIVKQLQQTECGLCCCAMLIRFYNSNETLFELRSFL
                     EAGRDGLTIKQLKNLLVHKGFKADIYKSTILGLKKINVPFIAYWNNEHFIVVEKIKENY
                     YYIIDPANGRRKLTEEEFKKGFSSYILYAVPSESFTPNKRKDKNVWFGVLKNITNYKLL
                     FSIIVFLSLISYLLTLYVPILVQKLIDTSIEYNNLNSISNIVWITFLISILYGMFVLFR
                     GLKMISLNIFLSKNLVVDTFAHLLKLPFKFFDLRSPGDLLFRLNSMNGFRELLSTQLIS
                     GLIDLGAVVFILAYMFFKSIPLTLITILIFAINTIFMFLTRPAVAQAIDDEVAEQSKSQ
                     AIQIESIFSIAAIKISGMENEIFSTWNNSFNEVIKRFKKRSILQNVVNTVTQVFQTIAP
                     LVILILELLLFFDNKFTMGEVIAYHSLSVTFFGLTTALFGTYTQFILATSYLERVKDIT
                     ETECEKNIENAVNLKLRGNVKLENVSFSYTKHSPKVLKNISLEIREGQKIAIVGSSGSG
                     KSTLSKLIMGLYDPTEGQICFDSIPLEKLDRKQLYKQMGIVPQDITLFNSSILKNITLN
                     NKNISIEKVRKVAKAAQIDKEIESMPMKYNTPISEMGMNLSGGQRQRIVLARALLNDPK
                     ILILDEATSSLDLVNETLISKYLSEMGCTRVVIAHRLSTIMDSDFIIVLDKGEVVEVGK
                     HEELIALEGVYSNLYRSQTKKQKTYSS"
     gene            18564..18734
                     /locus_tag="G9F75_RS12575"
                     /old_locus_tag="G9F75_12505"
     CDS             18564..18734
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="G9F75_RS12575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="G9F75_12505"
                     /product="hypothetical protein"
                     /protein_id="WP_155238646.1"
                     /transl_table=11
                     /translation="MKNYKGDGAVFLVIGFCLGLFLGVVFDILPYGLSIGILIGSLIDL
                     YFYARYKNNNK"
     misc_feature    18816..18829
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.22"
                     /tool="antismash"
     gene            19049..19989
                     /locus_tag="G9F75_RS20105"
                     /pseudo=""
     CDS             19049..19989
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="G9F75_RS20105"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRVSDPVEVKQKV"
     gene            complement(20049..20510)
                     /locus_tag="G9F75_RS12580"
                     /old_locus_tag="G9F75_12510"
     CDS             complement(20049..20510)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151638.1"
                     /locus_tag="G9F75_RS12580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12510"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_021495213.1"
                     /transl_table=11
                     /translation="MQKLSIRKAAEPDEALYELLLLADPSKEIVDDYLVRGECYTAWTS
                     DELAGVFVLLKTRPKTVEIVNIAVKESMHNNGIGRKLIEEAVNKAKQMGAATIEIGTGN
                     SSIGQLALYQKCGFRLQAIDHDFFIRHYEEEIFENGIQCRDMIRLYLDL"
     misc_feature    20545..20558
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.2"
                     /tool="antismash"
     gene            20642..22420
                     /locus_tag="G9F75_RS12585"
                     /old_locus_tag="G9F75_12515"
     CDS             20642..22420
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014305844.1"
                     /locus_tag="G9F75_RS12585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12515"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_021495212.1"
                     /transl_table=11
                     /translation="MFFCKYCGQQNNEEAHFCKECGKPIGKGSRLERQAAESASQPRKP
                     IPKKTLFLWGGIAAALILLIAAYKTGAWLTSEKRLTDQFEQAVHDGDTKKLAALLTPSD
                     KKLKLNETNVKPLLAYAKKHDELLASLRGNSSEKDAVYVKKEGKTLLLFDHYELKVDPV
                     YFRVTSNYKGADLYINSEKTGTVKKADETQIFGPYAPGVYTAEAKLKNETVDVVKKQEA
                     EAAGSRNVEFDLPLDAEDVTFTPADSFKSVKGDLLINGKSVHKDPFTSVTYGPLLTDGS
                     MTAAVEADFPWGKMKTADVPINSTDVDLTLIPDQDTQQTIMDTIVKTTKQYTKAMADGN
                     TDQMTEAGSAWKEQTKEAVSGMKSSGTFLKDQYKETSFDLDSFAISQENGRWQVTVTGK
                     ELHESAYFDGNTKPDMEEAEPSFHYVLSYDTKHKKWVFEKADPASDSSGTNVKKIKNDQ
                     PNTYTSAWASSKGNTASGSVTNEQVTSFMTDYLTNQSSAVSLNNFAIMAGNLEEGSPLY
                     ADQQKLVKKLHSEGTTEVFNEVNVKSFSQKGSHLTIHTYEEFYITKAGGSPKLRTYNWT
                     YGGVVKDGRIYLTSIQ"
     gene            complement(22460..23170)
                     /locus_tag="G9F75_RS12590"
                     /old_locus_tag="G9F75_12520"
     CDS             complement(22460..23170)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007409971.1"
                     /locus_tag="G9F75_RS12590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12520"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_167409128.1"
                     /transl_table=11
                     /translation="MYCSQCGHHTDGGKFCEKCGAPQPGQGGAGQTQGQAAQAGAAAKQ
                     ASKQFALFVLDVLKRPYQTCKTTGGEQLVSSIINIVLFCLVTPIMFYILLSDGFRDVSF
                     TAVVIKPALTFALCVFCLYLLIFIALKAGGAQVSFKDSLSRFGAFLIPFTAILLLALIF
                     MLLHTTVCFTILAVGLLGAAFAVPPLMLASYQHQLTAKADIIYSVIVIYLIICVTFQFT
                     IKHYIKELMNYFFF"
     CDS             23327..23395
                     /gene="allorf_143609_143677"
                     /locus_tag="allorf_143609_143677"
                     /protein_id="allorf_143609_143677"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MELIDIMSLGALIQSEEEINAC"
     CDS_motif       23327..23359
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MELIDIMSLGA"
                     /locus_tag="allorf_143609_143677_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       23360..23395
                     /prepeptide="core"
                     /locus_tag="allorf_143609_143677_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.50"
                     /molecular_weight="1230.3"
                     /monoisotopic_mass="1229.6"
                     /core_sequence="LIQSEEEINAC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MELIDIMSLGA"
                     /leader_location="[23326:23359](+)"
     gene            23608..24240
                     /locus_tag="G9F75_RS12595"
                     /old_locus_tag="G9F75_12525"
     CDS             23608..24240
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014471043.1"
                     /locus_tag="G9F75_RS12595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12525"
                     /product="NAAT family transporter"
                     /protein_id="WP_007409973.1"
                     /transl_table=11
                     /translation="MFSFIIHVFISLFAVSNPIGNVPIFLSLTEGYSEKERTAIARKAS
                     VLSFIILAAFLIFGHLIFKLFDINIHALRIAGGIFIFGIAYNLLNAKKSHVQSLHHEEK
                     GESKEKADISVTPLSIPIIAGPGTIATVMSLSAGHGGIFHYISVLIGIAAVIAMTFIFF
                     HYSSFISNKLGKTEMNVITRLMGLILAVVAIGMIGAGLKGMFPILVS"
     gene            complement(24263..24820)
                     /locus_tag="G9F75_RS12600"
                     /old_locus_tag="G9F75_12530"
     CDS             complement(24263..24820)
                     /codon_start=1
                     /function="Predicted transcriptional regulators"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014418904.1"
                     /locus_tag="G9F75_RS12600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12530"
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="WP_014418904.1"
                     /transl_table=11
                     /translation="MEKNALDIIGHAEEHLIERIAENMHTFGMPATLGRVLGIIYMNRK
                     PMTLNELSEATGMSKTRMSQVVREMTDANLAEKVFEKGVRKDLYDVERDYYQTFISLFT
                     ANWTKAVSKNKMLYKKLNRELTELLESENLSPDIEEKARQLLDELTDWLHYYDWLSRLI
                     EFFESEEVFQHVPKIEKSSTRR"
     CDS             complement(24846..24992)
                     /gene="allorf_145128_145274"
                     /locus_tag="allorf_145128_145274"
                     /protein_id="allorf_145128_145274"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLKLYTIYVFFHVIPLTMRMFLQSLPIARISCRIIFFINCKKYDI
                     LSA"
     CDS_motif       complement(24909..24992)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /locus_tag="allorf_145128_145274_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(24846..24908)
                     /prepeptide="core"
                     /locus_tag="allorf_145128_145274_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2367.9"
                     /monoisotopic_mass="2366.3"
                     /core_sequence="RISCRIIFFINCKKYDILSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /leader_location="[24908:24992](-)"
     CDS             24877..24960
                     /gene="allorf_145159_145242"
                     /locus_tag="allorf_145159_145242"
                     /protein_id="allorf_145159_145242"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMKKMMRQDMRAIGSDCKNIRIVSGIT"
     CDS_motif       24877..24921
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMKKMMRQDMRAIGS"
                     /locus_tag="allorf_145159_145242_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       24922..24960
                     /prepeptide="core"
                     /locus_tag="allorf_145159_145242_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1282.5"
                     /monoisotopic_mass="1281.7"
                     /core_sequence="DCKNIRIVSGIT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMKKMMRQDMRAIGS"
                     /leader_location="[24876:24921](+)"
                     /alternative_weights="1300.5"
     misc_feature    complement(24968..24986)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 29.41"
                     /tool="antismash"
     misc_feature    complement(25040..25054)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.56"
                     /tool="antismash"
     gene            25081..26220
                     /gene="opuCA"
                     /locus_tag="G9F75_RS12605"
                     /old_locus_tag="G9F75_12535"
     CDS             25081..26220
                     /codon_start=1
                     /gene="opuCA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013353644.1"
                     /locus_tag="G9F75_RS12605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="G9F75_12535"
                     /product="osmoprotectant ABC transporter ATP-binding
                     protein OpuCA"
                     /protein_id="WP_003151651.1"
                     /transl_table=11
                     /translation="MLRLENVSKVYKGGKKAVNSIDLNIEKGEFICFIGPSGCGKTTTM
                     KMINRLIEPSSGKIFIDGENIMEQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPKLL
                     KWPEQKRKERARELLKLVDMGPEYLDRYPHELSGGQQQRIGVLRALAAEPPLILMDEPF
                     GALDPITRDSLQEEFKKLQRTLNKTIVFVTHDMDEAIKLADRIVILKAGEIVQAGTPDD
                     ILRNPANEFVEEFIGKERLLQSRPDIERVEQMMNKKPVTVTADKTLSQAIQVMREHRVD
                     SLLVVDDLNVLQGYVDVEIIDQNRKKASLVGDVLRSDLYTVEQGTLLRDTVRKILKRGM
                     KYVPVVDEQRHLVGIVTRASLVDIVYDSIWGEEDQLVTG"
ORIGIN
        1 ggatgctcgc ttacggcatg attccgtccg tcatcttttt tatcgtgctg cttatcgtgc
       61 ctgaaagccc gcgctggctt gcgaaagcgg ggcgccggaa tgaagccctc gccgtgctga
      121 cgcgcattaa cggcgagcag accgcgaaag aagaaatcaa acaaatcgaa acgtctttac
      181 aattagaaaa aatggggtca ttgtctcagc tgtttaaacc ggggctgaga aaagcgcttg
      241 tgatcgggat tctgctggct ttattcaatc aggtcatcgg catgaacgca attacgtatt
      301 acgggccgga aattttcaaa atgatgggct tcggacagaa tgcggggttt atcacgacat
      361 gcatcgtcgg tgtcgttgaa gtgattttca ccattatcgc ggttctttta gtcgataagg
      421 tgggccggaa aaagctgatg ggggtcggat cagcctttat ggcgctgttc atgatcttaa
      481 tcggggcatc cttttatttt aagctggcga gcggtccggc tttagtcgtc atcatattgg
      541 gattcgtcgc cgctttctgc gtatcagtcg ggccgattac gtggatcatg atttcggaaa
      601 tctttccgaa ccacctccgc gcacgcgccg ccggtatcgc gacgatattc ttatgggggg
      661 ccaactgggc gatcggccag ttcgtgccga tgatgatcag cgggttaggg ctcgcgtaca
      721 ccttctggat attcgccgtc attaatattc tctgtttctt gtttgtcgtg acgatctgcc
      781 ctgagacgaa aaataaatca ttagaagaaa tagaaaaact ctggataaaa tgaaagcgtt
      841 ttacgacaaa agtccgctcc ggcgggcttt tgtctgtcac cttcattccg tttctgtata
      901 taatgactgt atcaaggaga tactgggaaa tcctgcgaag aatgtcgacg aattgacctt
      961 taacagttga attaacaatg tcatcctgtt aaaataatta aagaaagcag acataatttt
     1021 ttttggctat gatgggacgt tttttgtcat agcgggacat tttctgtcca gtatgaatag
     1081 gaaggaacgt ttgagtcatg aaccagttaa tacaagctca aaaaaaatta ttgcctgatc
     1141 ttttgcttgt gatgcagaaa agatttgaaa tcttgcagta tatcaggctt accgaaccga
     1201 tcggccgcag aagtcttgca gccagtctcg gattgaccga gcgcgttctc agaagcgagg
     1261 ttcagttttt gaaagaacag aatctcatcg atattaaaac aaacggcatg acaatgacgg
     1321 aagagggcta ctcactgctt tcgattctgg aagatacgat gaaggatgtt ttaggattga
     1381 cgcttttgga aaagacatta aaagagcggc ttaatctgaa agacgccatt atcgtttccg
     1441 gagacagcga ccaatctcct tgggtcaaaa aagaattagg gagagcggcc gttgcatgta
     1501 tgaaaaagag attttcaggc aaaaatatcg tcgctgtaac cggcggtacg acaattgaag
     1561 ccgtcgccga tatgatgacg ccggattcaa aaaaccgcga gctcctgttt gtgcccgcaa
     1621 gaggcggttt aggcgaagat gtgaaaaacc aggcgaacac catatgcgcg catatggcgg
     1681 aaaaggcttc aggcacttac cggcttttgt tcgttcccgg gcagctgtca caaggcgcct
     1741 actcatctat tattgaagag ccttccgtaa aagaggtgct tcacacgatt aaatcagcga
     1801 gtatgctcgt tcacggaatc ggcgaagcta gaacaatggc ggagcgaaga aacacgcctt
     1861 tggaagattt gaagaaaata gatgacaatc atgcggtgac agaggcattc ggctactact
     1921 ttaatgcgga cggagaagtc gttcacaagg tgcattcagt cggaatgcag cttgatgacc
     1981 tcgatgccat tcccgacatt atcgcggtag cgggcggatc atcaaaagca gaagcaatcg
     2041 aagcttattt taaaaagcag cgaaacacgg ttctcgtcac ggacgaagga gccgcaaaga
     2101 agttattaag ggataacagt ccctcaatat aaatatctct cacttattta aaggaggaaa
     2161 taatcatggc agtaaaagtc ggtattaacg gttttggtcg tattggacgt aacgtattcc
     2221 gcgcagcatt aaacaatcct gaagttgagg tagtagcggt taacgattta acagacgcta
     2281 acatgcttgc tcatctttta caatatgatt ccgtacacgg aaaattagat gcagaagtta
     2341 aagttgacgg cagcaacctt gttgttaacg gcaaaacaat cgaagtttct gctgagcgcg
     2401 atcctgcgaa actcagctgg ggcaaacaag gcgttgaaat cgtagttgaa tctactggtt
     2461 tcttcacaaa acgcgcagac gctgcgaaac acttagaagc aggcgcgaaa aaagttatca
     2521 tctctgcacc tgctaacgaa gaagatatca caatcgttat gggtgttaac gaagacaaat
     2581 acgatgcggc taaccaccat gttatctcta acgcatcttg cacaacaaac tgccttgcgc
     2641 cgtttgcaaa agtacttaac gacaaattcg gcatcaaacg cggtatgatg acaactgttc
     2701 actcttacac aaacgatcag caaattcttg atcttccgca caaagactac cgtcgtgcgc
     2761 gtgcagcagc tgaaaacatc attcctacat caactggcgc tgctaaagca gtttccctcg
     2821 ttcttcctga actgaaaggc aaactgaacg gcggagctat gcgtgtgccg actccaaacg
     2881 tttctcttgt tgacctagtt gctgaactga acaaagacgt aacggctgaa gacgtaaacg
     2941 cagctcttaa agaagcggct gaaggcgatc ttaaaggaat ccttggctac agcgaagagc
     3001 cattagtatc cggagactac aacggcaatg ctaactcttc tacaatcgat gctctttcta
     3061 caatggttat ggaaggcagc atggtaaaag taatctcttg gtacgataac gaaagcggct
     3121 actctaaccg cgttgttgac cttgcagctt acatcgcaaa acaaggtctt taattcatag
     3181 ctcccggaaa gggccggact tggttctttc ggacagaaac gctataatga aagcggacaa
     3241 gggaagggga cggactccct ttcccttttt ccatgagaac cggctttcag aaagcgccgg
     3301 attgctgcag aacgtccgcg ttttgaagtt tccgcggcac tttcgttttc ttagccgcct
     3361 gccctggctc agaagacgat ctgccccgtg cccggaagct gcaatctgcc ccgcggcgga
     3421 agcatcatga ggcggtttca cgtttcacgt ttttcgtgct atgcaaacca ttttgaagga
     3481 ggatctccta aggcatgaat aaaaaaacag taaaagacat cgacgtaaaa ggcaaagtcg
     3541 tattctgccg cgttgacttt aacgttccaa tgaaagacgg ggaagtaaca gacgatactc
     3601 gtatccgagc tgcgcttcca acaatcaaac accttgcaga ccaaggcgcg aaagtccttc
     3661 ttgcgagcca cttaggccgc ccgaaaggcg aagtggttga ggagcttcgt ttaactcctg
     3721 tcgctgcacg cttaggcgaa ctgctcggaa aagaagtgaa aaaagcggat gaagcttacg
     3781 gcgatgctgt aaaagcacaa atttctgata tgaaggacgg agacgttctt gtattggaaa
     3841 acgtacgttt ctaccctggt gaagagaaaa acgatcctga gcttgctaaa gcatttgctg
     3901 agcttgcgga tgtatatgtc aatgacgcat tcggtgctgc ccaccgtgct cacgcatcta
     3961 cagccggaat tgccgagcat ctgccggcgg ttgcaggatt cttgatggaa aaagagcttg
     4021 acgttctcgg caaagccgtg acaaatcctg agcgcccgtt tacggcaatc atcggcggcg
     4081 cgaaagtaaa agacaaaatc ggcgtaatcg aaagtctgct tgataaagtg gacaacctga
     4141 tcatcggcgg aggtcttgct tacacattcg taaaagcgct tggctatgaa gtcggtaaat
     4201 ctttgcttga agaagataaa atcgaacttg caaaatcatt catggaccgc gcgaaagaaa
     4261 aaggcgttac attctatatg ccggaagacg tgctcgttgc tgatgatttc tctaacgatg
     4321 caaacgttca aatcgtgccg atctctgaga ttccaagtga tttagaagcg atcgacatcg
     4381 gaacgaaaac ccgcgaaacg tatgctgaag ttatcaaaaa cagcaaactt gtcgtatgga
     4441 acggaccgat gggcgtattc gaaatcgact tgttcgctca aggcacaaaa gcagtggctg
     4501 aagcattggc agaggcaaac gatacatact ctgtcatcgg cggaggagac tctgcggcag
     4561 ccgttgaaaa attcggcctt gctgacaaaa tgagccatat ctcaacaggc ggcggcgcat
     4621 cccttgaatt catggaaggc aaagagcttc cgggtgtagc tgcgctgaac gataaataaa
     4681 aactgctata aggaagtgga acagatgaga aaaccaatta tagccggtaa ctggaaaatg
     4741 aacaaaacac tcggcgaagc tgtcagcttc gttgaagaag tgaaatcttc cattccagca
     4801 gcagacaaag cggaagccgt tgtttgcgca ccagctcttt tcttagaaaa gctgacttct
     4861 gctgttaaag gaactgacct gaaagtcggc gcccaaaaca tgcattttga agaaaacggt
     4921 gcgttcacag gtgaaatcag cccggtcgct ctgaaagacc ttggcgtgga ttactgcgtc
     4981 atcggccact ctgagcgccg tgaaatgttc gctgaaactg atgaaacagt taacaaaaaa
     5041 gcgcatgccg ctttcaaaca cggcattgtg ccgatcattt gcgtaggtga aacgcttgaa
     5101 gagcgcgaag ccggaaaaac aaatgatctt gttgccgatc aagtgaaaaa aggtcttgcg
     5161 ggtctttctg aagagcaagt tgccgcttcc gttattgcgt atgagccaat ctgggcaatc
     5221 ggaacaggca aatcttctac agcgaaagat gctaacgacg tctgcgcgca tatccgtaaa
     5281 gtcgttgctg aaagcttcag ccaggaaact gctgacaagc tccgcattca atacggcggc
     5341 agcgtaaaac ctgcaaatat taaagaatat atggcagagt ccgatattga cggtgctttg
     5401 gtcggcggcg caagccttga accgcagtca ttcgttcaat tattggagga aggtcaatat
     5461 gagtaaaaaa ccagctgcac tcatcattct tgatgggttc ggattacgca atgaaacagt
     5521 cggaaacgca gtcgcacaag cgaaaaaacc gaatttcgac cgttattgga accaataccc
     5581 tcatcagacg ctgacggcat caggcgaagc agtcggactg cctgaaggac agatggggaa
     5641 ctctgaagtc ggtcatttga atatcggcgc aggacgtatt gtgtaccaaa gcttaacacg
     5701 cgtgaacgtt gccatccgcg aaggcgaatt cgaacgcaat caaacgttcc ttgacgccat
     5761 caaaaacgcg aaagacaacg acaaagcgct gcacctgttc ggccttcttt ctgacggagg
     5821 cgtacacagt catatcaatc atttattcgc gctgctgaag cttgcgaaaa gtgaaggact
     5881 gacgaaggtg tatattcacg gtttcctcga cggccgcgat gtaggtccgc aaacagcgaa
     5941 aacttacatt cagcagctga atgagcagat cgaagaaatc ggtgtcggcg aaatcgccag
     6001 catttccgga cgctactact ccatggaccg cgacaaacgc tgggaccgtg tggaaaaagc
     6061 gtaccgcgca atggcttacg gcgaaggccc gtcttaccgc agcgcgatgg atgtagtcga
     6121 tgattcttat gcgaacggca ttcatgatga attcgtcatt ccgtccgtca tcacaaaaga
     6181 aaacggtgaa cccgttgcga aaattcatga cggcgattct gtgattttct ataatttcag
     6241 accggaccgc gctatccaga tttcaaacac gtttaccaac aaagatttcc gcgatttcga
     6301 ccgcggtgaa aatcatccga aaaacctgta tttcgtctgc ctgactcact tcagtgaatc
     6361 tgttgacgga tatgtggctt ttaaaccggt aaaccttgac aatacggtgg gtgaagtatt
     6421 agcacagcac gggttaaaac agcttcgcat tgcagaaact gaaaagtatc cgcacgttac
     6481 gttctttatg agcggcggcc gcgaagaaga attcccgggc gaagagcgca tcctcattaa
     6541 ctcgccgaag gtcgcgacat atgacctgaa gcctgaaatg agcgcgtatg aagtgaagga
     6601 tgctcttgta aaagaaatcg cggctgacaa gcacgacgcg atcatcctga actttgcaaa
     6661 ccctgacatg gtcggccact ccggaatggt cgaaccgacg attaaagcaa ttgaagcagt
     6721 ggacgaatgc ttaggcgaag tggttgacgc catcatcgct aaaggcggac atgccatcat
     6781 taccgctgat cacggtaatg cggacattct gattacagaa acaggcgaac cgcacactgc
     6841 ccatacgaca aacccagtcc cagtcattgt gacgaaagaa ggcgtgacgc tgcgcgaagg
     6901 cggaatccta ggcgacctcg caccaacgtt attagacctt ctcggtgttg aaaaaccgaa
     6961 agaaatgaca ggaacatctt taattcaaaa ataagcgtaa atcaaaagga gagacaaact
     7021 catgccatac attgttgatg tttatgcacg cgaagtcctc gactcccgcg gcaacccaac
     7081 agttgaagtt gaagtatata cagaaacagg agctttcggc cgcgcattag tgccaagcgg
     7141 agcttctaca ggtgaatacg aagcggttga gcttcgtgac ggcgacaaag accgttacct
     7201 tggaaaaggc gtgttaactg ctgttaacaa cgtaaacgaa atcatttctc cagagcttct
     7261 cggctttgac gtaactgaac aaaacgcaat cgatcagctt ttaatcgagc ttgacggaac
     7321 tgaaaacaaa ggcaaactcg gtgcgaacgc aatccttggc gtatctatgg cttgtgcgcg
     7381 cgcagctgct gatttcttac agattcctct ttaccaatac cttggaggat tcaactcaaa
     7441 aacgcttcct gtaccgatga tgaacatcgt aaacggcgga gagcatgctg acaacaacgt
     7501 agacattcaa gaattcatga ttatgcctgt aggcgcgcct aacttccgtg aagcgcttcg
     7561 catgggcgct caaatcttcc acagcctgaa atcagttctt tctgctaaag gaatgaacac
     7621 agctgtaggt gacgaaggcg gattcgctcc gaaccttggt tctaacgaag aagcgcttca
     7681 aacaatcgtt gaagcaatcg aaaaagccgg cttcaaacct ggcgaagaag tgaagcttgc
     7741 tatggatgct gcatcttctg agttctacaa caaagaagac ggcaaatacc atctgtctgg
     7801 cgaaggcgtt gtgaaaacat ctgctgaaat ggttgactgg tacgaagaaa tggtttctaa
     7861 atacccaatc atctctatcg aagacggact tgacgagaac gactgggaag gccacaaact
     7921 tcttacagag cgtcttggca aaaaagttca gcttgtcggt gacgaccttt tcgttacaaa
     7981 cacgaaaaag cttgctgaag gtatcaaaaa cggcgtaggc aactctatcc tgatcaaagt
     8041 aaaccaaatc ggtacattga ctgaaacatt cgatgcgatc gaaatggcga aacgcgcggg
     8101 ctacactgcc gttatctctc accgttcagg tgaaactgaa gacagcacaa tcgctgatat
     8161 cgctgtggca actaatgcag gacaaatcaa aacaggtgct ccgtcccgta cggaccgtgt
     8221 tgcgaaatac aaccagcttc ttcgcatcga agatcagttg gctgaaactg ctcaatacca
     8281 cggtatcaac tctttctata acttgaataa gtaagcataa aaagggcttg gctgcatctg
     8341 cagccaagcc cttttaagtg tgggagagct gaatttctag aatttctatt accctgacaa
     8401 aagcagtcag ggtttttttg agttggagtg tttgaatgat caaaatcagt ttatctttac
     8461 gcatttccta caatgttagg ttgggaatat ggataattaa gaccaaactg aacttgcaaa
     8521 gtttcaaata agatgccgca cttttaaaag tcatgacaat agggtgaata aagaaatgat
     8581 aactacgctc gagcttagcg cataaaacca gatatctccc ttgatgaatg gatgttcgag
     8641 agtacagacc tactaatatt actcggatcg aatatctgag gctaaaaatt tcactagccg
     8701 atcttgaaaa aggacagtga agctttaaag cttacaggag gatggttatt actttttacg
     8761 gagtaactgt cggtttagcg aatagcagac gcttggaatc aagaaaacat acaagaaatg
     8821 ataacatttg cattttatga tatggaactc ccggtatcta gtaggaatct ggttactgca
     8881 tcaggagaaa actctcttag accccgagag aagtattgaa aaataaacca tgtttgaaca
     8941 actgtataca ttggatcatg gtatccgctc aataaaactc accaactcgg acacttcttc
     9001 aaatttaatg aaaacattca attaatgtaa ggttgtgagt ataactagta tttagttaat
     9061 gacaaagcat ggtctgaccc tttcaatatt cctaaaacga gaagtaaaca atcttgtgat
     9121 cacagatact tatatcctta attcagccat ctcagataca gaacggatag tcattagctg
     9181 tgccctagat aaaaaacaat ggtctacagc tgcccggaat ttagctgcat ataatactta
     9241 taaaagttaa ggtagtagct gattgtgttg acgccctctc agaacaaaat aatagttact
     9301 taattcctta ttaatctaaa taattttgat gacaactcca aaagaaagta ttctctcctt
     9361 taaataagag ttcctgtgta acataactgt tgttctttta cttgcaaaag gcaggattac
     9421 gatatttttt attttaaaat ttgtgatgca gtaatgtgaa aaccgtttta tttctttcct
     9481 aaagcatttt aaaaattaca ttcctaaaaa caaaggactt ctttttggta ttataaaaaa
     9541 ctgccctgtt aaaataaagt ataaaatacc cccccgagaa tctcataaaa taaaaaaatt
     9601 acataaaacc cattgtttac tataggaaaa tatggtagat tattattgaa caggttaata
     9661 gagattttat ccagtaaaaa atgaggaggt agatagtatg aagaagacaa agatattaaa
     9721 aacaccagaa ttgaaagtga caaaagattt aaatttgata gacccatgtg gagatgttct
     9781 tgaagaaatt aaagaacatg aagtttcagg agctttcaat acctggaata caacaactac
     9841 tagcctgggg ggcattttag taagtgaggt tcttggaaat aaaggcaaag tttgtacagg
     9901 tactaaagaa tgtcaaggta cttgctgaaa taagtataaa ataggcagtg taattaactg
     9961 cctattttgc aaaaaatata ttaaggtagg atcattaact ttgaaaacta acaaatataa
    10021 tctccaatac tggatgaaaa tgtttcctga ggttaacaat aaagatgaat tgcaaaagat
    10081 ttttttaaat gtatctggta agacgattca atcattaatt agagacgata ctaatattga
    10141 gcaaaataaa agtattatag atattgatag agtcttagat cataaaaaaa gtgatttttt
    10201 agtgagaaat tctgaagaat ttttagagca taatccattt tttcattttt tttctccttt
    10261 tcttaactgc aaaattgaag aattcttagt aaaagtaaga attgaagatg cagtagataa
    10321 tgaggatgaa tttgtgaaaa aggtaattaa acatataatg gatttaatgt ttgaaaaagc
    10381 ttttagggtt cttgttttgg aagtgaatat tgcaagatta gaggggaatt tagaggggac
    10441 taccccggaa gaaagactaa atcatttttt agttgtatct ttaaatgatg aatcattttt
    10501 aaaaagtgtt tataaagaat atgaagtatt aacaagttta ttatgtgtaa cgattgatga
    10561 ttatttcaca tatgtaatgg aaataataaa aaacacaaaa cgagaaatta gttcattaaa
    10621 ctctaaattc aactctgata acgatttagg tgcaataaca aatataacca ccggtctagg
    10681 agatactcat caaaaaggaa aatctgtttc aacaatatat tttaaaagtg gcaagaaaat
    10741 aatttataaa cccagagatt taacgcttga acaaggtttc caggaagtat tatattggtt
    10801 gggcgagaaa aacataccgg gaattttaaa tttcaaaaga gttcaaatac atacagtaaa
    10861 tgattcaggt tggatggagc acatagatta taaaagttgt tttaataaaa acgaagcaaa
    10921 tgatttctat actcgttcag gtaatcttct ttgtttactg tatcttctaa atgcagtaga
    10981 ttttcatcat gaaaatttaa tagcccatgg ttctttccca gtattagttg acttagaatc
    11041 attatttcat gcaagactaa aggttgacca aattgataaa aagtcagctg ttgttaaagc
    11101 aactgaatta gttgataact ctgtacagtc aataagttta ttgcctacaa aaatttctaa
    11161 gagagtagga gacaaagaca taagtctaga tataggggga ttagctgcct ataaggaaca
    11221 actctctcct cataaatcat tagtaattga aaatgcagga acagatacga ttaaaatttt
    11281 aagaaaaaat actttcatta aacctcaatt aaacaaccct tccattaaaa cagggtctta
    11341 cttatattca gaaaattata cgggacaaat taaagatggt tttgcaagtt tatatagttg
    11401 ggtgatgtta aataaagatg aattctggga taaaatttct caaactttta aagaaacaaa
    11461 tagcaggttt atcttcagac ccacttactt atacactcag cttttaagaa tctcaagtca
    11521 tccagatttt atgagagata cctatagacg taagattatt ttacatagaa tcggcattga
    11581 ttatatacaa gagtataaag atatattgaa ctcagaatat aaagatttat taactgggga
    11641 cgttccattt tttagatcct ctattgaaca tgaacattta atagattcta gagggaaaag
    11701 aattcacagc attctggaag aacctccaat aaaaacagta aagcaaaaga ttttcaatct
    11761 ttcgaaagaa gatttgaaaa gacagattga ttttattgaa atgtcttaca ttagtaatga
    11821 aaaaagattg aaagaagtta ctgatataaa attctctaaa gctgcaagct taaataaaat
    11881 taagtcagaa aattggatag atgaagcaac ccagataggc gaatttatag ttgaaaacag
    11941 tgtatgtggt ataaataaaa aacaaaaaga tagaatgtgg ataggtccta gtcttgaggg
    12001 tattgaggaa gacatttgga atgcaaatgt attgggattc gatatatata atggtaattc
    12061 agggattgct ctatttttag ggtacttggg cgaaatcctc aacagaaagg attttaagca
    12121 agcagctatc gaaactatga gaccaataca gaagtttatc tctgaaataa aagaagatca
    12181 cccatattta ataggtgcat ttcaaggtat atcaggatat ttttatacat taaataagtt
    12241 atctaattta tttggagatt cagaattaag gaagacctcg cttgaaaaca tcggtgtttt
    12301 atcgaagtta ggtaaattcg ataaagtata cgatttaata ggagggtctt taggtagttt
    12361 agcagttatg ctttccataa taccagatat tactgaagag aataacaaaa aggaaatttt
    12421 aaagatttca catactcatt gtgaacatat attaagtgta gcaaaaaatt ttgaggagca
    12481 aatatcgtgg ccagggaaat tttcagcagc atattcaggg ttttcccatg gtaattctgg
    12541 ttttatcgca tacttatata aatattttaa gttaacaaat gatgaaaaat tattggaagt
    12601 cattcaaagg gccttaagat ttgaaaggag attgtactct gaagaccaca ataattggta
    12661 taccacagaa aataaagata agttagctaa tggatggtgt cacggagctc caggtatact
    12721 tttaagtaaa ttgattttaa aagataatgg ttttgaagac gagtacattg aaaaagaaat
    12781 atcgactgca atagattctt ctattcgtaa tggcattggc aataacccta catattgtca
    12841 tggagattta ggtgtgcttt ctatattgaa ttatgcttct gatttaacta acaatattaa
    12901 tttgaagaat agatgtttaa gaacttatca agacctattt gaaaatgttt tgaccaagaa
    12961 atggagaaag agagacttag tctgtactag atcatatagt ttaatgatcg gattatcagg
    13021 aataggttac tcaatgatca aaaattatgc tccggaaatt gttcccaatt ttttatggtt
    13081 agaataagct ttaatactct tattcaaagt catacttgaa aggaggtgag agaattatga
    13141 agaaagatat ggtcaaaaag gtttcaggtt ttattgaaga agacgaactt atatcgttag
    13201 ctaatggtga taatgctact ggaggagcta ctccagcaac agtcgtttta actgcaacta
    13261 ttggactcac tggaacgact tttacagtta ctttaagtgc agcatcatgt ccaacatcag
    13321 cgtgtacaaa acagtgtaac aaataaacat aatgtgttaa tagagaattg ttttaacaaa
    13381 caattctcta ttaaatcttt tggagaggtt ataaatggat attagctatg aaaacaataa
    13441 tttcatcaga gatgctgtaa ttaatttcag ttcgccgaca aacgaagtag aaaaattaag
    13501 aataaaaaac aaagattact ttggcaactt ttatacattc tttttagatt tttatcaaca
    13561 aaaattagtt aatactttag aaaacgcaag taaggaaaat aatttaaaac ttaacaaaca
    13621 taaaattata agtagtgcgt tagaggcttt tagccaggaa ttaattcagt tatgtataag
    13681 aactttaatc gttgatatta atgaaagaaa agaaaatggt ttattagaag gaaaagattc
    13741 aaggttacgc tataagaatt ataataattt aatttttaag agtgaatatg tggctggaat
    13801 tttgaataag tatcctgttt taacctattt aatttctagt agaatatcaa ataaaatctt
    13861 gtacttgaaa gaagttctag agaatttaag aaaaaatcgt caagacattt atagagaact
    13921 aaaaattgaa tttgatgaag tctccaatat ttattttagc agcggagaca ctcataatgg
    13981 agggaaaaat gtcttaataa ttgaaacaaa ccaagggaaa attgtatata agccgcatag
    14041 tttatctcct gatatcttat ttaatagtat agttgactat gttaataatt cagataaaat
    14101 tctaaaaaaa atttataaaa ttagaacgct taattataaa gactatggct atcaagagtt
    14161 tattgattat aaagaatgtg agacttccga aaaactgaac ttctattttt atagagtagg
    14221 tgtaagttta tctatttttc acattatagg atgcgatgat ttgcatcatg aaaacttaat
    14281 tgcacatggc gaatatcctg ttgttattga cttggagact ctgataaaaa ataattctat
    14341 gtataaacca agaaataata atttaattga taattttcat gaggatatta attactcagt
    14401 tcttggcact atgcttctcc cattaaattt acaaacttct atatttgatt ttgaccttgg
    14461 cggaatatca aatgatgaaa atcaaacatc agaaatatgg aaatcgtata ttatagattt
    14521 cgaaggaact gatgaaattc agttaactaa aaaatcagta ataatgaaca gtactcaaaa
    14581 cagagctgca tataatggga aagccgcaga ccctaaagat tatattgaag aaatattaaa
    14641 aggttttaca gattgttata attttgtttt agaaaataaa agtggttttt atgatttggt
    14701 aaaaacagta ggaagcagca acctggaagt aaggcaagtt ttaagagcta ccagtatata
    14761 tgcaaggttt ttagaagctt ccactcatcc aaattattta tctagttttg aggaaagaaa
    14821 ggaattattt aaaaaaataa atattgcgga aggagtaaca gataaattta gcaagaagaa
    14881 tttaaatgag ttggaatctt taatgtgtaa tgatgttccg tatttttcaa caatgtataa
    14941 ttctttggat ttgatttgta ataaaagtac aagtatagta aattttttta gagagtgttt
    15001 acttgatgtt gtattaaaca aaattaaaag tataagtaaa acaagtttaa aaaaacagca
    15061 atattatatt cgaatgtcac ttactacaac tataaaagac agttggaaaa gaacaaacaa
    15121 acacaataag aaatatcgtc ctaaattatt tggaaataat aataaaaatt atttagagtg
    15181 cgcaacagaa ataggagact tatttttaga aacagcaata tggaataatg atagaagcaa
    15241 atgtacttgg gtaacaccta taatatctga gaataataaa gtaaaattgg gtccattgaa
    15301 ctttaactta tatgaaggtg gaggagtaat attattctta gctttacttg gaaaagaaac
    15361 tggtaataaa gagtactttg atttagcctt tgcaggaatg agaggtattg aagaactttt
    15421 tttgagtgat gataagatgg atggccggtt atcattattt acagggatag gttccttagc
    15481 ctatatatat taccacctat acacttatac aaatgattat aaatactatg aaaaatttaa
    15541 aaaatatatt aataaaataa atgaaatgaa tatttcagga gatataccat tggatattgt
    15601 agggggagta tctagtctta ttgttttttt attaaaccta tataaggaaa ctaaattaga
    15661 tattttaaac tccgtgtgtt gtaaactagg taatacttta tatcaatgct tagaaaagaa
    15721 tggtaaatat aattatctaa caggactttc acatggatat tctggtttta cgtgggctct
    15781 ttgttatctg ggtcacatta ctaaagacga aaaatacaca actttaggaa aagagttatt
    15841 gaaaagagaa aataagtttt ttgatttgaa tacctctaat tggaaggatt taagagaagg
    15901 agaggggaac tctgatccag tatattggtg tcatggtgcg ggaggtatag ctctatcaag
    15961 agctttttta aaaaatctgt taaagaacaa agagaacgta gttgataaag aagttgataa
    16021 agaagttgat aaagaagttg ataaagattt aaattgcgct ataagcaagc tcctttccga
    16081 tggatttaaa aaaacaactg atcatagctt atgtcatggt atttttggta atatagatat
    16141 attattgaaa ttaagtgaac ttctcaatga tattgatctt caggaagtag catttaaaga
    16201 agctcaaaat gcaattaatt atattagaaa taaaggtttt attccaggtt tacaggatca
    16261 ttttgattta aatacattta tgctgggact tggaggcgta ggctacagct tattaaggtt
    16321 acacaatcct gtcaatcctt cattgttagc aatggaagta aggagttaca atgaatgata
    16381 gtgaagaaaa aaaagagagt acctattgta aaacaattgc aacaaactga atgtggactt
    16441 tgctgttgtg ctatgttgat ccgtttttat aacagtaacg aaactctttt tgagttaagg
    16501 tcatttttgg aggctggaag agacggactt actattaagc agttaaaaaa cttattagtt
    16561 cataaaggat ttaaggcgga tatatataaa tccactattc tagggttaaa aaaaattaat
    16621 gttcctttta ttgcatattg gaataatgaa cattttatag tcgttgaaaa aataaaggaa
    16681 aattattatt atattataga tccggctaat ggacgaagaa aattaacaga agaagagttt
    16741 aagaaaggtt tctcgtccta tattttatat gcagttcctt cagaaagttt cactcccaat
    16801 aaacgaaaag ataagaatgt atggtttggt gtattaaaaa atattacaaa ctataaattg
    16861 ttattttcta ttatagtatt tttatctcta ataagttatt tattgacgtt gtatgtacct
    16921 attttggtac agaagcttat agatacaagt attgagtata ataatttaaa ttcaataagt
    16981 aatattgttt ggataacatt tttaatatca atattgtatg gaatgtttgt tttgtttaga
    17041 gggctcaaaa tgataagcct caatatattc cttagtaaaa atcttgttgt tgatacattt
    17101 gctcatcttc taaaacttcc ttttaaattc tttgatctta gatcacctgg tgacttgtta
    17161 tttaggttaa atagcatgaa tggattcaga gagcttttat caactcaact aatttctggc
    17221 ctaattgatt taggagcggt agtttttatt ttagcgtata tgttctttaa atctatacca
    17281 ttaaccttga taacaatatt aatatttgca attaacacta tattcatgtt tttgactaga
    17341 cctgctgtcg cgcaggccat cgatgatgaa gtagctgagc aaagtaaatc tcaagccatt
    17401 caaatcgagt ctattttttc tatcgcagcc attaaaattt cgggaatgga aaatgaaatt
    17461 ttctcaactt ggaataacag ttttaatgaa gtaataaagc gattcaaaaa aagatccatt
    17521 ttacaaaatg tagttaatac agtaactcag gtttttcaaa caattgctcc cttggttatt
    17581 ttaatattag aactgctatt attttttgat aataaattta caatgggaga ggttatcgca
    17641 tatcattctt tatctgttac tttttttgga ttaacaactg ctttatttgg tacttatact
    17701 cagtttatct tagctacttc ttacttagaa agagttaaag atattacaga gactgaatgt
    17761 gaaaaaaata ttgaaaatgc agtaaacctt aaattaagag gaaatgtaaa gcttgaaaac
    17821 gtctcttttt cttatactaa acattctcca aaggtgctta agaatatttc tttggaaata
    17881 agagaagggc agaaaattgc tatagtaggt tcatctggtt ctggtaaaag tacacttagt
    17941 aagttaataa tggggcttta tgatccgact gaaggacaaa tttgttttga tagtatccct
    18001 cttgaaaaat tagatagaaa acagttatac aaacaaatgg gaattgtacc ccaggatatt
    18061 accttgttta atagttctat actgaaaaat atcacattga ataataaaaa tattagtata
    18121 gaaaaagtga gaaaagtagc gaaagcagca caaatagata aagaaattga aagtatgcca
    18181 atgaaatata atacacctat ttcagaaatg ggtatgaatt tatcaggtgg ccagcgacaa
    18241 aggattgtac tagccagagc acttttaaat gaccctaaaa ttttaatttt agatgaggct
    18301 acaagttcat tagatttggt gaatgaaaca ttgatttcta aatatttaag tgaaatggga
    18361 tgcacaagag tggttatcgc gcatagattg tcaacaatta tggattcgga ttttataatt
    18421 gtcctagata aaggtgaagt ggtggaggtt ggtaaacatg aagaactgat tgctttagaa
    18481 ggggtatata gtaatctata tcgttcacaa acgaaaaaac aaaaaacata ttcatcataa
    18541 tcactattaa ggagttgttt gatttgaaaa actataaagg agatggagcg gtatttctag
    18601 taataggttt ttgtttaggt ctttttttag gagttgtttt tgatatttta ccgtatggtc
    18661 tttccatagg aatattgatt ggatcgttaa ttgaccttta tttttatgct agatacaaaa
    18721 ataataataa ataagtataa ttatatctta aacatcaaga tcaatgagga gattttattc
    18781 ctttgggcag caactgagaa atttgtgtta aactttaaaa ttattttaat gaatttaaaa
    18841 ttagaatggt ataaagaaca taagagtttt atggattatt aagttttaat ctattacttg
    18901 atgttcctac caacaaaaga ttgcaacttt atgtctttag aaaaaacaaa gggactgacc
    18961 tataagatga gccaaaaaaa aacactttca agtttgaaaa cggatgactg ttatccggta
    19021 ttagacttgg aggtgttttt tctatggaat aagagtaagt gatccggttg aagtcaaaca
    19081 gaaggtgtag acatgagatt ggcaggcgtg ccgatgaaag agatgatgca gaaattaaat
    19141 attaagaata cacggacgtg cagacttgga ttagatagca taaagctggg gatatacatt
    19201 cgaacagcct gttgaaaagc aatatactta cggaaatggt ctggggttta cttccgaacc
    19261 agagactgca ggcagagaat cgttatttgc gacagccgaa tgaagtgtta aaagagtaca
    19321 acgaattaga aaggaagtta aaagccaaac ttcagtcgga cttgtagaag gttttgcaga
    19381 tatctgtgat cttttaggta tctcacgagc gtcttattgt ctctgaaaga aaaatgtgaa
    19441 gaagaatcag tgcaaagggc atttggaaaa acacattggc gcattatgcc gaaagcatgg
    19501 gtatcgatag ggctattgga tcatcacttc cctaataaaa aaggaaatgc gtgttaacca
    19561 taaaacgttt cagcgtatca ttcagaaaaa tcagtagcag taccggatta aggatgcaag
    19621 aaaaatgagc atatttatgc cgcaactgat aatatggaac tttcagcctg atctccctct
    19681 tgaaaaaata gtaacagact tcccgaattt tccttatagt cagaataatt gtatctgttc
    19741 gcgatattgg aagtatacaa tggagaagtg aatgctttta cgattggaga taaacaggac
    19801 acacacttga tcagctgcca attttgcctg agagctgcgt gttgcatagt gtcagaaaag
    19861 ctgttaaaac aaaaccacgc ccgtcatcgt agaatgcact gtcaacgatt acatttataa
    19921 taacaatatt cgtattcaaa cgaactaaac agccaatcat tgatagacga gcggcaattg
    19981 gctgtttaaa agtgttttta tccctgtctc gaaaacgggg tttaatcgca tcattggcag
    20041 ttcttttatt aaaggtccaa ataaagccgt atcatatccc ggcactgtat cccgttttcg
    20101 aaaatctcct cttcataatg cctgatgaaa aaatcatggt cgatggcttg aagtctgaag
    20161 ccgcattttt ggtaaagggc aagctggcct atactggagt tgcccgttcc aatttcaata
    20221 gtcgccgctc ccatttgttt tgccttattc acggcctctt ctatgagctt tctgccgatg
    20281 ccattgttgt gcattgattc tttcaccgca atattgacga tttctactgt ttttggtctt
    20341 gttttcaaaa ggacgaagac ccctgcaagc tcgtctgacg tccaagccgt atagcattct
    20401 cctcttacaa gataatcatc gacaatctct ttcgacggat cggccagcag caatagttca
    20461 tacagcgctt catccggctc cgcggctttt cggatgctca gtttttgcat gtccgtttct
    20521 cctcctccgt tatgatcgac agctattttt caaaataact ccaaaatcat tctactttat
    20581 tataaaatat gaaacatagg aaaagttata caagttttgc agattgaata ggaggaaagt
    20641 catgtttttt tgtaagtatt gcggccagca gaacaacgaa gaggcgcatt tctgtaaaga
    20701 atgcggaaaa ccgatcggga aaggaagccg gctggagcgg caggcggctg aatccgcatc
    20761 acagccgaga aagccgatcc ctaaaaaaac gctcttccta tggggaggca ttgccgcagc
    20821 gctgatctta ttgattgccg catataaaac cggagcctgg ctgacatctg aaaaaaggct
    20881 cacagatcaa ttcgaacagg cggttcatga cggggacacg aaaaagctcg cagccctgct
    20941 cactccttca gacaaaaaac tgaagctgaa tgagaccaat gtcaaaccgc tccttgcata
    21001 cgcaaagaaa cacgatgaac tgctggcatc gcttcgcggc aattcatcag aaaaagatgc
    21061 ggtatacgtc aaaaaagagg gaaaaaccct tcttttgttt gaccattacg aactgaaagt
    21121 cgatccggtt tatttccgcg tcacaagcaa ttataaaggc gccgatcttt atatcaacag
    21181 cgagaaaaca ggtacggtca aaaaagccga tgaaacccaa atcttcggcc cgtatgcacc
    21241 cggtgtctac acggcggaag ccaagcttaa aaatgagacg gttgacgttg tcaaaaagca
    21301 agaggcagag gcggccggca gccggaatgt tgagtttgac ctgccgttag acgccgagga
    21361 tgtgacgttc actccggcag acagcttcaa aagcgtgaaa ggcgatctgc tgataaacgg
    21421 caagtccgtc cataaagatc cgtttacatc cgttacatac ggtccgctct taactgacgg
    21481 ttccatgaca gccgccgtgg aggctgattt tccttggggg aaaatgaaaa ctgccgatgt
    21541 tccgatcaac agtactgatg tggacttaac gcttatcccg gatcaagata cacaacaaac
    21601 aatcatggac acgattgtca aaacaacgaa gcagtataca aaagcgatgg cagacggaaa
    21661 tactgatcag atgaccgagg ctggttccgc ctggaaagag cagacgaaag aagcggtatc
    21721 cggcatgaag agttccggca cctttttgaa ggatcagtat aaagagacaa gctttgatct
    21781 ggattcattt gcgatttctc aagagaacgg ccgctggcaa gtaactgtta cgggtaaaga
    21841 gcttcatgag tctgcttatt tcgacgggaa tacgaagcct gatatggaag aggctgagcc
    21901 gagttttcac tatgtactct catatgatac aaaacataaa aaatgggttt tcgaaaaagc
    21961 tgatcctgcc tcagattctt ccgggacaaa tgtaaaaaaa ataaaaaatg accagccgaa
    22021 tacctataca tccgcatggg catcatccaa aggaaataca gcttcaggca gcgtgacaaa
    22081 cgagcaagtc acatcgttta tgactgatta cctgacaaat caatcaagcg ccgtcagcct
    22141 taacaatttt gccatcatgg cgggcaattt agaagagggg agccctttgt atgctgatca
    22201 gcagaaactg gtcaaaaaac tgcacagcga ggggacgacc gaagtattta atgaagtgaa
    22261 tgtcaaaagc ttttcacaga aaggctctca tctgacgatt catacgtacg aggagtttta
    22321 tattacgaaa gccggcggca gtccgaagct cagaacatac aattggacgt atggcggcgt
    22381 tgttaaagac ggaagaattt atttaacatc cattcaataa aaaacccccg cgccaatcag
    22441 gcggcggggg tttccgtttt taaaagaaga aataattcat gagttctttt atataatgct
    22501 tgatcgtgaa ttgaaacgtt acacaaatga tcaaatagat gacgataaca gaataaatga
    22561 tatcggcctt agccgtgagc tgatgctgat agctcgccag catgagcgga ggcacggcaa
    22621 acgccgctcc taaaagaccg acagccagaa tggtaaagca gacggttgta tgaagcagca
    22681 taaaaatgag ggcaagaagc aaaatagctg taaacggaat caaaaatgct ccgaatctgg
    22741 acagcgaatc tttaaatgac acctgcgcgc cgccggcctt caaagcgata aaaatcaaga
    22801 gatacaggca gaaaacgcat aatgcaaagg taagcgccgg tttgatcaca accgcggtaa
    22861 aactgacgtc acgaaagccg tctgatagaa gaatataaaa cataatcggc gtcaccaggc
    22921 agaaaagcac tatgttgatg atgctgctga caagctgttc gccgcctgtc gttttacatg
    22981 tttgatacgg tcgctttaac acatcaagca cgaataaggc aaattgcttt gaagcctgct
    23041 tagcggcggc gccggcctga gcggcctggc cctgcgtttg gcctgcgcct ccctgcccgg
    23101 gctggggcgc accgcacttt tcacaaaact ttccgccatc agtatgatgg ccgcattgag
    23161 aacaatacat tctaaaactc cttttacaag taatataggg attttgttca atatttacat
    23221 tataaaagaa aatagggcgg atgtaacgga gttttctaaa gatatacaaa tcactttctc
    23281 tatgaattga taatagagaa aaagtaccca ttatggtaga attttaatgg agctgataga
    23341 tatcatgtct ctcggcgcat tgattcagag tgaagaggaa attaacgcat gctaaaaaaa
    23401 ttgaaaatgc tttatcggct gttgaaattc ggaaaaggct tatggagata gcaaacagaa
    23461 aaaaccgtcc ttgtaaggac ggtttttttc tgtttccgga tcgtccggct gaggttataa
    23521 aaagcagacc ccggggtaaa aaccatgcat aagaaacagc ggtgaacaaa acataactca
    23581 ataacggcaa gccataagga ggtacgcatg ttttcattca tcattcatgt cttcatttca
    23641 ctgtttgcag tctccaatcc catcggaaac gtgccgattt ttctttcact gacggaaggg
    23701 tactcggaga aagaacggac agcgatcgcg cgcaaggctt ccgttctgtc gtttatcatc
    23761 ttggcggctt ttttaatctt cggccatctg atctttaaac tgtttgacat taacattcat
    23821 gccttacgta tcgcgggcgg catttttatt ttcggcatcg cttataatct tctgaacgcg
    23881 aagaaatctc atgtacagtc tctccatcat gaagagaaag gggagagcaa ggagaaagct
    23941 gatatatccg tgacgccttt gtcgattccg attatcgccg gacccggtac gatcgcgacg
    24001 gtgatgagtc tgtcggccgg ccatggcggc atcttccatt acatcagcgt gctgatcggc
    24061 attgcggccg tcatcgcgat gacgttcatc ttctttcact attcttcttt catcagcaat
    24121 aagctcggga aaaccgaaat gaacgtcatt acccgactga tggggctgat tttggcggtg
    24181 gtggcgatcg gcatgatcgg cgccggtctg aaaggcatgt tcccgatatt ggtttcctga
    24241 cttaaaaaaa agcagcgccc ggttatcttc gggtgctgct tttttctatt ttcggcacat
    24301 gctgaaacac ttcttcactc tcaaaaaatt ctatcaaacg gctcagccag tcataataat
    24361 ggagccaatc cgtcagttca tccaaaagct ggcgggcttt ttcttcaata tcgggactga
    24421 gattttccga ttccagaagc tcagtcagct cgcggttcag ctttttatag agcattttgt
    24481 ttttgctgac cgcctttgtc caatttgccg taaacaggga gataaacgtc tggtaataat
    24541 cacgctcgac gtcgtaaagg tctttccgaa cgcctttttc aaacactttt tcagccagat
    24601 tggcatcggt catttcgcgg accacctggc tcatcctcgt tttgctcatc ccggtcgcct
    24661 ctgacagctc atttaacgtc atcggcttgc ggttcatata aataataccg agcacacgtc
    24721 caagtgtggc cggcattccg aatgtatgca tattctcggc gattctctca atgagatgct
    24781 cttcagcatg cccgatgata tcaagagcgt ttttttccac ggctgatcat cccttcactg
    24841 gcttttcatg ctgacaatat atcatatttt ttacagttga tgaaaaagat gatgcggcag
    24901 gatatgcgag ctatcgggag cgattgtaag aacatccgca ttgtcagcgg gataacatga
    24961 aaaaatacgt atattgtata taatttcaac acattgtaaa ctttttattt tacaaatttc
    25021 atcttataat aaagattata cttttcagaa aaataacgga acccttcgga ggtgcacgga
    25081 ttgctgagat tagaaaatgt atcgaaagtc tataaaggcg gaaaaaaagc tgtcaacagc
    25141 attgatttaa atatcgaaaa aggcgagttt atttgtttta tcgggccgag cggctgcgga
    25201 aaaacgacga cgatgaaaat gattaacaga ctgattgagc cgtcatccgg aaagattttt
    25261 atcgatggcg aaaacattat ggagcaggac ccggtggagc tgagacggaa aatcggctac
    25321 gtcattcagc agatcggact tttccctcat atgaccattc agcagaacat ttccctcgtg
    25381 ccgaaactgc tgaaatggcc ggaacaaaag cggaaggaac gggcacggga gcttttgaag
    25441 ctcgtcgata tgggcccgga atatttagac cgctatcctc acgagctgag cggcggacag
    25501 cagcagagaa tcggcgtgct gcgcgccctt gcagcggaac cgcctcttat tcttatggat
    25561 gaaccgttcg gagcgcttga tccgattacg cgggattccc ttcaagaaga attcaaaaaa
    25621 ctgcaaagaa cattgaataa aacgattgtg tttgtaacac acgatatgga tgaagctatt
    25681 aagctggctg accggatcgt cattttaaaa gcgggagaga tcgttcaggc cggcactcct
    25741 gatgacatcc tccggaatcc ggctaatgag tttgtcgaag aatttatcgg caaagaacgg
    25801 ttattgcaat caagaccgga cattgaacgc gtcgagcaga tgatgaacaa aaagcctgtc
    25861 accgttacgg cggacaaaac gctttcgcag gcgatacagg tgatgcggga acaccgtgtc
    25921 gattccctgc ttgtcgttga tgacctgaat gtgctgcaag gatatgtgga tgtcgaaatc
    25981 attgatcaga accggaaaaa agcgagcctc gtcggcgacg tgctccgctc tgatctgtat
    26041 acggtcgagc aggggacact gctgcgtgat accgtacgca aaattttaaa gcgcggaatg
    26101 aaatatgtac ccgtcgttga tgaacaaagg catttagtcg gaattgtcac gagagcgagc
    26161 cttgtcgaca tcgtttacga ttcaatctgg ggcgaggaag accagctggt gacaggctga
    26221 caaggggagg aacgcttaca atgaatgaaa tgatcaagtt tttgcagacg aacggcggag
    26281 aactgttata taaaacgtgg gagcatttat acatttcgat catcgccgtc atattaggca
    26341 ttgtcgtcgc cgttccgctc ggagtggcgc tgacgaga
//
