LOCUS       NZ_CP070373            13146 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8340254
            Orig. end                         :: 8353400
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13146
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="38"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13146
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13146
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8146](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..8146)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    966..980
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.13"
                     /tool="antismash"
     misc_feature    complement(1000..1020)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.8"
                     /tool="antismash"
     gene            1064..1267
                     /locus_tag="GWQ54_RS36770"
     CDS             1064..1267
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125862.1"
                     /locus_tag="GWQ54_RS36770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cold-shock protein"
                     /protein_id="WP_031141049.1"
                     /transl_table=11
                     /translation="MAAGTVKWFNAEKGFGFIEQDGGGPDVFAHYSNIAAQGFRELQEG
                     QKVNFDIAQGQKGPTAENIVPA"
     gene            1666..3207
                     /locus_tag="GWQ54_RS36775"
     CDS             1666..3207
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985583.1"
                     /locus_tag="GWQ54_RS36775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_167158694.1"
                     /transl_table=11
                     /translation="MNRTRTNDRYSRTNNSGGSGAPRGGSRFGSSGGSGRFGSSGRSGS
                     SGRSGGYGRRSSGPQGEFALPVTITPALPAVEAFAELALPAQLLAELAQQGLSVPFPIQ
                     GATLPNSLAGRDVLGRGRTGSGKTLAFGLAMLTRTAGRRAEPRQPLALVLVPTRELAQQ
                     VTDALTPYARALRLRLATVVGGMSIGRQAGALRSGAEVVVATPGRLKDLIERRDCRLDQ
                     VDITVLDEADQMADMGFMPQVTELLDQVRPGGQRMLFSATLDRNVDLLVRRYLSDPVVH
                     SVDPSAGAVTTMEHHVLHVQSADKYATTTEIAARDGRVIMFLDTKHAVDQLTKHLLQSG
                     VRAAALHGGKSQPQRTRTLAQFKTGDVSVLVATNVAARGIHVDNLDLVVNVDPPTDHKD
                     YLHRGGRTARAGESGSVVTLVTPNQRREMSRLMVNASIVPQTTQVRSGDEELTRITGAQ
                     APSGIPVTIKAPVVERPRRSASASSSRGRRSRPSQDRRAARPARAAEPRQSGTAA"
     gene            3297..3605
                     /locus_tag="GWQ54_RS36780"
     CDS             3297..3605
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964502.1"
                     /locus_tag="GWQ54_RS36780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SCO5918 family protein"
                     /protein_id="WP_167158692.1"
                     /transl_table=11
                     /translation="MRCVIARFPFDLSKAQVVAAMKGIKPEPVEGDSVLIGRRHYPVKQ
                     VGEVITRQDRRDFSAQEVTRAMTRLGFTCQGLPQAAPARTLTPLEAASEMLGVSALA"
     misc_feature    complement(3800..3810)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            3805..4140
                     /locus_tag="GWQ54_RS36785"
     CDS             3805..4140
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047013.1"
                     /locus_tag="GWQ54_RS36785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_161249623.1"
                     /transl_table=11
                     /translation="MTADSPLTGRLDDDDYPAYTMGRAAEMIGASPGFLRALGEARLIT
                     PLRSEGGHRRYSRYQLRIAARARELVDQGTPVEAACRIVILEDQLEEAQRLNAEYRAAA
                     DKDPGSH"
     gene            complement(4246..4953)
                     /locus_tag="GWQ54_RS36790"
     CDS             complement(4246..4953)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938955.1"
                     /locus_tag="GWQ54_RS36790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_167158690.1"
                     /transl_table=11
                     /translation="MGHLKQSKVITTTERLRDQVAHALRAALISGELRPGQVYSAPGLA
                     EEFGISATPVREAMLDLAREGLVEPVRNKGFRITEVNERDLDQYTEIRALIEVPMIGRI
                     TRSADRADLEALRPVAEEIVRAARDHDLIGYLEADRRFHLSLLALSGNERLVETVGDLR
                     KRSRLYGLTALDQRDELIPSAEEHIELLDLMLAGDARAAEKCMTRHLGHVRSLWARSEA
                     AEPKPKRRLGATR"
     misc_feature    4989..4999
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(5001..6425)
                     /locus_tag="GWQ54_RS36795"
     CDS             complement(5001..6425)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606671.1"
                     /locus_tag="GWQ54_RS36795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_240361940.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3e-20, bitscore:
                     71.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.7e-11, bitscore:
                     43.1, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDLVVVGAGPAGLAGAGTAGELGLRVALLDMAEHVGGQFYRQPA
                     AGLGAARPEALHHDWDAFVALRKRLAAGRVEHLGRHHVWAVERGADGDWAVHAVVGDDG
                     GDGRPVRVRARAVLLATGAYERQLPFPGWTLPGVVGAGGAQAMLKGGLVLPGKRVVVAG
                     SGPLLLAVASSLASAGAEVPAVIEASGYLGYARHPRALAVNPRKLAEGLTHGAALLRHR
                     IALRTRSAVTEAHGSERVEAVTVSRLDARWRPVPGSGRRIACDALAVGHGLVPGIELGT
                     TLGCGTRTTADNTLALHLGSGQETSVRGVWGAGEVGGVAGAQLARIEGELAARSIAARL
                     GRDPGPERRVRQLSSRRTRLRTFAEAMAATHAPGPGWTGWLCDDTEVCRCEEVTAGRVR
                     AAVADQGARDARTVKLFTRAGMGWCQGRMCGAAVSCLAGDGQPPAQRRPLAVPLTLGAL
                     AGQGPEDASEPSQSQT"
     gene            complement(6633..6947)
                     /locus_tag="GWQ54_RS36800"
     CDS             complement(6633..6947)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237883.1"
                     /locus_tag="GWQ54_RS36800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_189766463.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.6e-26, bitscore: 90.9,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTPGELAGARPGPAFEITVDGRAVSALPGQTVAAALWAAGVLT
                     WRTTRGGGRPRGVFCGIGQCFDCLVTVNGVANRRACLVAVGPGDEVRTQEGEGRGELAV
                     "
     gene            complement(6980..8146)
                     /locus_tag="GWQ54_RS36805"
     CDS             complement(6980..8146)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891271.1"
                     /locus_tag="GWQ54_RS36805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_205530749.1"
                     /sec_met_domain="DAO (E-value: 1.4e-63, bitscore: 214.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTPDVIVVGAGIVGAACAHYAARAGLRVTVLDRGPVAGGTTGS
                     GEGNLLVSDKAPGPELELALKSAELWRELAERLPHGIEYEPKGGLVVASGEAALTALRT
                     FAAAQEKAGVTVRDVAADRLPDLEPHLARGLAGGVHYPQDAQVMPALAATHLLRASGAE
                     VRLGQEVTGLLTGPGGAVRGVRTASGVFHAPYVVNAAGTWGGELARLAGVLLPVLPRRG
                     FVLVTEPLPRVVRHKVYAADYVADVASDSAALQTSAVVEGTPAGPVLIGASRERVGFDR
                     ALSVPALRRLAAGATVLFPVLAGVRVIRTYAGFRPYLPDHLPAIGTDARVPGLLHACGH
                     EGAGIGLAPVTGRIIADCLTGAQPPLDIAPFDPARFEGGTGVGAGAGA"
     misc_feature    complement(8156..8171)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.03"
                     /tool="antismash"
     gene            complement(8845..9963)
                     /locus_tag="GWQ54_RS36810"
     CDS             complement(8845..9963)
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01413.1"
                     /locus_tag="GWQ54_RS36810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_167158683.1"
                     /transl_table=11
                     /translation="MSDPGFRRRALLATLPMAFAASGCEAAAPRRERDRRPVQGPPPGP
                     VRQPGVAEPQQPHMLFVSYDLTPGTRGAPGRDAVRRLLARWSELLAGLAPGPTATVGIG
                     PGLPERLGVGAPEGLRELPAFAGEHLDVAAGGGEIGVQICARDARGCERLAGLLAGAGA
                     GVLRPRWRQAGFLSGERPGPRSELLAPPRAGEASRDLLGFKNGTSNPTAAENERWVWLP
                     PGGRYADGTFLVVRRIRLRVEEFGRLPVARQEQIVGCRKGGGEVLSSDLNARTPEGSYV
                     LPLDAHVRLAGPGPDGGARMLRRSYSYENSPGDRGMLFLAYMRDPALFVRVGTRLAASD
                     ALNSFAEQYGSALFYVLPGVGGSGRALGSTVL"
     misc_feature    9984..9997
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.34"
                     /tool="antismash"
     misc_feature    complement(10124..10137)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.54"
                     /tool="antismash"
     gene            10143..10733
                     /locus_tag="GWQ54_RS36815"
     CDS             10143..10733
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380449.1"
                     /locus_tag="GWQ54_RS36815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_331445237.1"
                     /transl_table=11
                     /translation="MIIPGIDGSDEHHWQSEWERHWGSSAVRTAPDSWSEPDLEDWVAA
                     VGSAVDEASRKHDHVVLVAHSLGCWAAATWLDRSPSPAATAAFLVAPPDPLSPAFPSGS
                     APTFTQLSARPLPIPALVVAGTNDPYCAPETSAAFAAQWGAQHHLAGPIGHINSGSLLG
                     SWEEGRDLLDSLLPPAHTPDLTPTPAPAPDTAA"
     gene            complement(10805..11002)
                     /locus_tag="GWQ54_RS36820"
     CDS             complement(10805..11002)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473994.1"
                     /locus_tag="GWQ54_RS36820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_100579590.1"
                     /transl_table=11
                     /translation="MPPPTPDITYTQCKRCGTELAGLDGRYSCGVCGWSNHWSEGHRPL
                     PRAEDDPDAPPTPVNPLGEQ"
     misc_feature    11163..11178
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    11244..11258
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.45"
                     /tool="antismash"
     gene            11336..12994
                     /locus_tag="GWQ54_RS36825"
     CDS             11336..12994
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944278.1"
                     /locus_tag="GWQ54_RS36825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_167158681.1"
                     /transl_table=11
                     /translation="MISEQIAAVVVAARDGDQRARDELVAGYLPLVYNIVGRALGGHAD
                     VDDVVQESLLRMLDGLGSLREPAAFRSWLVAVTMNEIRRYWQGHRRTPVDGGLQDAHDL
                     ADPGADFVDLTIVRLGLSGQRKEVTEATRWLEPDDRALLSLWWLEAAGVLSRGEVASAL
                     DLSAEHAAVRVQRMKGQLETARVVVRALAGIERCGELYGLALSWDGVPSALWRKRIARH
                     ARTCAVCSGHWSGLIPAEGLLVGLALVPVGAATAGLLAVLGGRAPALETTAHATAATQP
                     SPRAAHGAHAAGRRRAPASRRDRRDRRTRRRRRAAAVIAGLAAVAALGGAYRFVTDPGQ
                     DSSRTVADAPLTTTDAASADGLSTGPLSPSPSASNSPTKASSSPSPSAPVKHSSPPPAT
                     KSPTHAAPPRPAPSTKRAAAGPDDGTPAAVQQVLDLVNSERSKAGCSALTSNPKLYDAA
                     LKHSENMAAQNFFDHTDPSGAGPGERITAAGYQWSSYGENIARGQADAAAVMDSWMHSP
                     GHRANILNCGYKEIGIGVHYGSGGPWWTQDFGTRS"
ORIGIN
        1 accagggggg cctcgccacg cagcaactcc tggtgcaggg cggccagttc gggccccggg
       61 tcggcaccga gctcgtcgcg cagggcgcgg cggtagaggt cgtaccgggt cagggcggcg
      121 gccggtcccg cggtggcggc ctcgcagcgc agcagctcag ccaacacctc ctcgtcgcgc
      181 ggcagttcac gggcgagctg ggccagcggc cggaccgcgt ccgccttgcg gccgagccgg
      241 gcgagcgcga gtgcgcggca gcgcacgagg gtgcggtggg cgccgccgcg cgcgcggcgc
      301 agcgcggcca cggggtcgtg caggtcctcg ccgtccccgc tcgcgacgac accgtcccac
      361 agggcgagcc ccgcctccgc ctcggcgagc gcatcgccgt gcgcaccggc gcgggcccgc
      421 gcctcggcgg ccgccgcgcg cagcggcagg gccgagctgt cgacctgctc ctcgctgagc
      481 gcgaggcggt agccggccgg ggtgctggcg acgacgtcgg ggccgagctg cgagcgcagc
      541 cgtgacacca gtacctgcac cgccttgccg ggccgttcgg gcagctcgtc gtcccacagc
      601 ccctcgacga gccgcccggt gctgcatccg gcccgcaggt cctcggcgag cagcgcgagg
      661 agcccgcgca gccggggcgc ggtcacctcc tggccgcggt aggcgacgcg cgtaagcaag
      721 gtcaactcgg tggtcacccg tgcagagtag tcagcgcacg gcccgcggga cccctcccgg
      781 cccaacccgc ctgacgtccg ggggccgttg tgccgcaccg gaaaacgccg tccggccctc
      841 gccgcggtgc gcgtatatct gtcacggccg cacaagaatt aattgtcgcg gcctcaccag
      901 aatttctcgc gcgaccggcc gagcagaatt attgaccatg cttctgcgat tgcgccgtgc
      961 tactgtcgat atcagttgca gttgtggttc ccagcagggc aatcatcaca gtgacgcgga
     1021 gtccgcacgg cgtggtctcc gaaattgccc caaggagaat gacatggctg caggtaccgt
     1081 gaagtggttc aacgcggaaa agggcttcgg cttcatcgag caggacggtg gcggtccgga
     1141 cgtgttcgcc cactactcga acatcgccgc ccagggcttc cgtgagctcc aggaaggcca
     1201 gaaggtcaac ttcgacatcg cgcagggcca gaagggcccg accgccgaga acatcgttcc
     1261 ggcctgatcg tcgacacgca cttcgcagct ggggcccgca ccttggggtg cgggccccgg
     1321 ctcgtcgcgt tttcgggccc gaccgcccgt cccgccggcc ctcgcgcccg ccacgacggc
     1381 ttcgcgcccg ttccgccgtg agcacctgac cggcgagaac gcaccccacg cagcaccccg
     1441 agcagcaccg caccaccccg gatcgaccgc gcgccccgcc gcacggcagg gaccgcccgc
     1501 ccacggcgcc cgggattttc ttcgcacctc atcacagcga tgcgccccga atatcgaatt
     1561 cggcccgatg cgctttcgca tccgcccggc tcgttcttgc gattccccgt actgtgcttt
     1621 ctcccgggaa ttcctcgatg cgtgccgtat caaggaaggt tccgcatgaa ccgcacccgt
     1681 acgaacgatc gctacagccg caccaataac tccggcggct ccggcgcccc ccgcggcggc
     1741 agccgcttcg gctcttccgg cggctccggc cggttcggct cctccggccg ctccggctcc
     1801 tcgggccgct cgggcggtta cggccgccgc tcctccggcc cccagggcga gttcgcgctg
     1861 ccggtcacca tcaccccggc gctgcccgcc gtcgaggcct tcgccgaact cgcgcttccc
     1921 gcccagctgt tggccgagct cgcccagcag ggcctcagcg tcccgttccc cattcagggc
     1981 gcgacgctgc cgaactcgct cgccggccgt gacgtgctcg gccgtggccg caccggctcc
     2041 ggcaagaccc tcgccttcgg cctcgcgatg ctcacccgca cggcgggccg ccgcgccgag
     2101 ccccgccagc cgctcgcttt ggtcctggtg cccacgcgtg agctggccca gcaggtcacc
     2161 gacgcgctga ccccgtacgc ccgggccctg cggctgcggc tggcgacggt cgtcggcggg
     2221 atgtcgatcg ggcggcaggc gggtgcgctg cgttcgggtg cggaggtcgt ggtggcgacg
     2281 ccgggccggc tcaaggacct gatcgagcgc cgggactgcc gtctggacca ggtcgacatc
     2341 acggtcctgg acgaggcgga ccagatggcc gacatgggct tcatgccgca ggtcaccgag
     2401 ctcctcgacc aggtgcgccc gggcggccag cggatgctgt tctcggcgac cctggaccgc
     2461 aacgtcgacc tgctggtgcg ccgctacctg agcgacccgg tcgtgcactc ggtggacccg
     2521 tcggcgggcg cggtgaccac gatggagcac cacgtgctgc acgtgcagag cgccgacaag
     2581 tacgccacga ccaccgagat cgcggcccgt gacggccggg tgatcatgtt cctggacacc
     2641 aagcacgcgg tcgaccagct gaccaagcac ctgctgcaga gcggtgtgcg ggcggcggcg
     2701 ctgcacggcg ggaagtcgca gccccagcgc acccgcacgc tcgcccagtt caagaccggt
     2761 gacgtgtccg tcctggtcgc caccaacgtc gcggcgcgcg gcatccacgt cgacaacctc
     2821 gacctggtgg tcaacgtcga cccgccgacc gaccacaagg actacctcca ccgcggcggc
     2881 cgcaccgccc gcgcgggcga gtccggcagc gtcgtcaccc tcgtcacgcc caaccagcgc
     2941 cgcgagatga gccgcctgat ggtcaacgcg agcatcgtgc cgcagaccac ccaagtgcgc
     3001 tcgggcgacg aggagttgac ccgtatcacg ggcgcccagg caccctccgg catcccggtc
     3061 accatcaagg caccggtagt ggagcgcccc cgccggagcg cctccgcctc ctcctcgcgc
     3121 ggccgccgca gccgcccgtc ccaggaccgg cgcgccgccc gccccgcccg cgccgccgag
     3181 ccccgccagt ccggaacggc cgcctgagcc cgcacccggc accgcaccgg ggcgttcgcg
     3241 ccccggccgc cgaccgcaca cccggtcggt ccacccccca agccttggaa ggcatcatgc
     3301 gctgcgtcat cgcccgcttc ccgttcgatc tctccaaggc ccaagtggtg gccgccatga
     3361 agggcatcaa gcccgagccc gtcgagggcg actccgtcct catcggacgc cgtcactacc
     3421 ccgtcaagca ggtgggcgag gtcatcaccc ggcaggaccg ccgcgacttc agcgcccagg
     3481 aggtgacccg ggccatgacc cgcctgggct tcacctgcca gggcctgccc caggccgcgc
     3541 ccgcccgcac cctgaccccg ctggaagcgg cgtccgagat gctcggcgtg agcgcgctgg
     3601 cctgacccgg aaccgggcac accaccgcac gcgatcacca cgagggcccc gccgggacac
     3661 cggcggggcc ctcgtcgtgt gcccgtgttc gccgccccag ccggtcggcg cggcacccgg
     3721 ggcacccgat ggtgttgaat ttcccctcgg gcccgcggtc ccgcaaggca ccgcgaaccc
     3781 ccgacgcggt gcgaaagagg tgacatgaca gcggacagcc cgctcactgg tcgactggac
     3841 gacgacgact atcccgccta cacgatgggc cgggccgccg agatgatcgg tgcgagcccc
     3901 ggcttcctgc gcgccctcgg cgaggcccgc ctgatcactc cgctgcgctc cgaaggcggc
     3961 caccggcgct actcccgcta ccagctgcgc atcgccgccc gcgcccgtga gctcgtcgac
     4021 cagggcaccc ccgtcgaagc ggcctgccgc atcgtcatcc tggaggacca gctggaggag
     4081 gcccagcgcc tcaacgcgga gtaccgggcg gcggccgaca aggaccccgg ctcccactga
     4141 ccgccgcccc cgtccccggc acccccggac cggtcgagcc gtcgcccccg cccgatcgcg
     4201 cggaccgggc cggcgcgcgc gtgaacggcg ggggcccggc ggggttcagc gggttgcgcc
     4261 caggcggcgc ttgggcttcg gttcggcggc ctcgctcctc gcccacagcg agcggacgtg
     4321 gccgaggtgg cgggtcatgc acttctcggc cgcccgggcg tcaccggcca gcatgaggtc
     4381 gagcagctcg atgtgctcct cggccgacgg gatcagctcg tcgcgctgat cgagcgcggt
     4441 cagaccgtac aggcgggagc gtttgcgcag atcgccgacg gtctccacca ggcgctcgtt
     4501 cccggacagg gcgagcagcg agaggtggaa gcggcggtcg gcctccagat agccgatgag
     4561 gtcgtggtcg cgggccgcgc gcacgatctc ctcggcgacc ggccgcagcg cctccaggtc
     4621 cgcgcggtcc gcgctgcggg tgatccggcc gatcatcggg acctcgatca gcgcacggat
     4681 ctcggtgtac tggtcgaggt cgcgctcgtt gacctcggtg atccggaagc ccttgttgcg
     4741 caccggctcc accaggccct cccgggcgag gtcgagcatg gcctcgcgca cgggggtcgc
     4801 ggagatcccg aactcctcgg cgaggccggg cgccgaatag acctgtccgg ggcgcagctc
     4861 gccggagatg agcgcggcgc gcagcgcgtg ggcgacctgg tcgcgcagcc gctcggtggt
     4921 ggtgatgacc ttgctctgct tcaggtgtcc catgctgctg ttcctccgta ccgagcggag
     4981 acccagagta caatgtcacg ttacgtttgc gactggctcg gttccgaggc atcctcgggc
     5041 ccctggccgg ccagcgcccc gagcgtgagg ggaaccgcca acgggcgccg ctgtgcgggc
     5101 ggttggccgt ccccggcgag gcaggacacc gccgccccgc acatccgtcc ctggcaccaa
     5161 cccatgccgg cccgcgtgaa cagcttgacg gtacgggcgt cccgggcacc ctggtcggcg
     5221 accgccgcgc ggacgcggcc cgccgtgacc tcctcgcagc ggcacacctc ggtgtcgtcg
     5281 cagagccagc cggtccagcc cggccccggc gcgtgcgtgg cggccatggc ttcggcgaag
     5341 gtacgcagcc gggtgcggcg ggacgacaac tgccgcacgc gccgctcggg tccggggtca
     5401 cgaccgagcc gcgcggcgat ggagcgggca gccaactccc cctcgatccg ggcgagttgg
     5461 gcgcccgcga caccaccgac ctccccggcc ccccagaccc cccgcacgga ggtctcctgc
     5521 cccgaaccca ggtgcagggc cagggtgttg tcggcggtgg tccgggtgcc gcagccgagg
     5581 gtggtgccca gttcgatccc ggggacgagc ccgtggccga ccgcgagcgc gtcacaggcg
     5641 atccgccgcc cggacccggg cacgggccgc caccgcgcgt cgagccggga gacggtgacc
     5701 gcctcgacgc gctcggagcc gtgcgcctcg gtcaccgcgc tgcgggtacg cagcgcgatc
     5761 cggtgccgca acagggcggc gccgtgcgtc aggccctcgg cgagcttgcg ggggttgacg
     5821 gcgagcgccc gggggtggcg ggcatagccg agatagccgg acgcctcgat cacggccgga
     5881 acctcggccc cggccgaggc gagcgaggac gcgacggcga ggagcagcgg cccgctcccg
     5941 gcgacgacga cccgcttccc cggcagcacg agcccgccct tgagcatggc ctgcgcacca
     6001 ccggccccca cgacgcccgg caacgtccag ccagggaagg ggagttggcg ttcataggcc
     6061 ccggtggcga gcaacacggc ccgcgcccga acccgcacgg gccgcccgtc acccccgtcg
     6121 tccccgacga cggcgtgcac ggcccaatca ccgtccgcgc cccgctcgac ggcccacaca
     6181 tggtgccgcc cgaggtgctc gacccgcccg gccgcgagcc gcttccgcag cgcgacgaac
     6241 gcgtcccagt catgatgcag cgcctcgggc cgagcggccc cgagcccggc ggcgggctgc
     6301 cggtagaact gtcccccgac gtgttccgcc atgtccagca gcgcgacccg aagcccgagc
     6361 tcccccgccg tcccggcccc ggccagcccg gcgggccccg cccccaccac cacaaggtcg
     6421 aacaccccgg tcaccacacc aacaccgccg agctcacggc aaacgccccc atcatcacaa
     6481 ctccgcctcg tatcagctca gttggggatg cgcagagcac cgtgcccacc ccgcccgacg
     6541 tcaactcccg caggtgcaca gggaaccggg cgaccggcca ggcacggccc gcaccggggc
     6601 gcggcggagc cgcacccgct ccgggaccct gctcacaccg cgagctcccc acgcccctcc
     6661 ccctcctgcg tcctgacctc gtccccgggc cccaccgcca cgaggcacgc cctccgattg
     6721 gccacgccgt tgaccgtgac caggcagtcg aagcactgcc cgatcccgca gaacaccccc
     6781 cgaggccttc cacctccacg ggtcgttcgc cacgtcagaa cgcccgcggc ccacaacgcg
     6841 gccgcgacgg tctgccccgg cagcgccgac accgcccggc cgtccaccgt gatctcgaac
     6901 gcgggcccgg gccgggcccc ggccagctca ccgggggttc gggccaccac gtcctccttt
     6961 cccgaccgcc accggcgcct catgccccgg cccccgcccc gaccccggtc ccgccctcga
     7021 atcgagccgg atcgaacggg gcgatgtcca gcggcggttg ggctccggtc aggcagtccg
     7081 cgatgatccg gcccgtcacc ggggcgagcc cgatccccgc cccctcgtgc ccgcacgcgt
     7141 gcaggagccc cggcacccgg gcatccgtcc cgatcgccgg aaggtggtcc ggcagatacg
     7201 gccggaaccc cgcgtacgtc cggatcacgc gcacccccgc aagcacgggg aacagcacgg
     7261 tcgccccggc cgcgagccgc cgcagggccg gtaccgaaag ggcgcggtcg aacccgaccc
     7321 gttcgcggct cgcgccgatc aggaccggcc ccgccggagt cccctcgacc accgccgagg
     7381 tctggagcgc ggccgagtcg ctggccacgt ccgcgacgta gtccgccgcg tacaccttgt
     7441 gccgcaccac gcgcggcagc ggctccgtga ccaggacgaa gccccgacgg ggcagtaccg
     7501 gcagcaacac cccggccagc cgggcgagtt cgccgcccca ggtgccggcg gcgttgacga
     7561 cgtacggcgc gtggaacacg ccggatgcgg tccgtacgcc gcgtaccgca ccccccggac
     7621 ccgtgagcag ccccgtcacc tcctgcccga gccggacctc ggcgccggac gcgcgcagca
     7681 gatgcgtggc ggcgagggcg ggcatgacct gggcgtcctg gggatagtgg acgccccccg
     7741 cgagaccgcg agccaggtgc ggctccaggt cgggcagccg gtcggccgcc acgtcgcgta
     7801 cggtcacgcc cgccttctcc tgcgccgccg cgaaggtgcg cagcgcggtc agggccgcct
     7861 caccggaggc gacgaccagt ccgcccttgg gttcgtactc gatcccgtgc gggaggcgtt
     7921 cggccagctc tcgccacaac tctgccgatt tgagggcgag ttccagttcg gggccggggg
     7981 ccttgtcgga gacgaggagg ttgccctcgc ccgagccggt ggtgccgccg gccacggggc
     8041 cccggtcgag gacggtcacc ctcaggccag cgcgggccgc gtagtgggcg caggcggcgc
     8101 ccacgatgcc ggcgcccacg acgatgacgt ccggggtgct tgtcatgacc accccggtaa
     8161 tatttcacat ggcaccgcgt gtgccaagga gttggccggg gggggggctt gcccaccctc
     8221 ctgcccatcg ctcggggttg gatggttccg gcccctgggg ctgcgcccca gaccccgggg
     8281 ggtttgccca ccctccccca agctcttaat gagcaggggg gacccccatc ccgtgcggcg
     8341 ggttgcatcg gctgagccct ggggcttcgc cccagacccc ctgaggggct ccgcccctcg
     8401 gaccccgggc gggggctccg ccccctgcac ccccgttcgg ggctccgccc cggaccccgg
     8461 ggggcttgct gaccctcccc caagctctta atgagcaggg gggaccccca tcccgtgcgg
     8521 cgggttggat gagctgaccc ctggggcttc gccccagacc ccctgagggg ctgcgcccct
     8581 cgaacccccg caaggggctc cgccccctgc cccccccgtt cggggctccg ccccctgcac
     8641 ccccgttcgg ggctccgccc cggaccccgt tcgcgcctga acggcgctcg tcctcaaact
     8701 cccccaaggc ctcaagggcc aggggggacc cccatgacgg gctgaaatgc ccgatgccgg
     8761 ccagcaccga agctcttagg ggcgcgggga actgcgcgag aagcgagcac ggtgcgaagc
     8821 cgcaccaagg ggacaggacc ggggctacag gaccgtgctg cccagtgccc ggccgctccc
     8881 ccccaccccc ggcagcacat agaacagagc cgaaccgtac tgctccgcaa aggagttgag
     8941 tgcgtcggac gcggccagcc gggtgcccac ccgtacgaac agcgcggggt cccgcatgta
     9001 ggcgaggaag agcatgcccc ggtccccggg gctgttctcg taggagtagc tccgccggag
     9061 catccgggcg ccgccgtccg gcccgggtcc ggccaggcgc acatgggcgt ccaggggcag
     9121 gacgtaactc ccttccggtg tgcgcgcgtt caggtcggag gacagcacct ccccgccccc
     9181 cttgcggcac ccgacgatct gctcctgccg ggcgaccggc aaccgcccga actcctccac
     9241 ccgcaaccgg attcgccgca ccaccaggaa cgtgccgtcc gcgtaccgcc ccccgggcgg
     9301 cagccacacc cagcgctcgt tctccgccgc cgtggggttc gacgtgccgt tcttgaagcc
     9361 cagcaggtca cgcgaggcct ctcccgcccg cgggggcgcg aggagttcgg aacgcgggcc
     9421 ggggcgctcg cccgacagga agcccgcctg gcgccagcgc ggccgcagca cccccgctcc
     9481 ggctcccgcg agcagcccgg ccaggcgctc gcacccccgc gcgtcccgcg cacagatctg
     9541 cacgccgatc tcaccgcccc ccgccgccac gtccaggtgc tccccggcga aggcgggcag
     9601 ctcccgcagg ccctcgggcg ccccaacccc gagccgctcc ggcaggccgg ggccgatgcc
     9661 gacggtcgcg gtgggcccgg gcgccagccc ggcgagcagc tcgctccacc gcgcgagcag
     9721 ccgccgcacc gcgtcccgcc cgggggcgcc ccgggtgccg ggggtgaggt cgtaggagac
     9781 gaagagcatg tgcggctgct ggggctcggc caccccgggc tgccggacgg ggccgggcgg
     9841 gggcccctgg acgggccgcc ggtcccgctc gcgccgaggc gccgcggcct cgcacccgct
     9901 cgccgcgaag gccatgggaa gcgtggcgag aagcgcgcgg cgccggaacc ccgggtcact
     9961 caagtcatcg tacaaaacag tacatttcgt gagagaagtg ctcggtacga tacacctgcg
    10021 gcggcccggg tacggggatc tccgtaagcg gcagacgaag agcaacgggc agcacagcga
    10081 cagcaagcga tcgacaggcg atcagcgagc gatcagcgcg gggggaagcc atgttcggct
    10141 acgtgatcat tcccggtatc gacgggtccg acgagcacca ctggcagagc gaatgggaac
    10201 ggcactgggg gtcgtcggcg gtgcgcacgg cgcccgactc gtggtccgag ccggacctgg
    10261 aggactgggt cgcggcggtc gggtcggccg tcgacgaggc atccaggaag cacgatcacg
    10321 tcgtgctcgt ggcccacagc ctgggctgct gggcggcggc cacctggctg gaccggagcc
    10381 cctcccccgc cgccacggcc gcgttcctgg tggccccgcc cgacccgctg tccccggcgt
    10441 tcccgagcgg gtccgcaccg accttcaccc agctgtcggc gcgcccgctg cccatccccg
    10501 ccctggtggt ggccggcacg aacgacccgt actgcgcccc cgagacctcc gccgccttcg
    10561 ccgcgcagtg gggcgcccag caccatctgg ccggacccat cgggcacatc aactccggga
    10621 gcctgttggg cagttgggag gagggccggg accttctcga ctccctgctc ccgcctgccc
    10681 acacccccga cctcacgccc accccggccc cggcccccga cacggcggcc tgaaccggca
    10741 ctgctccccc acccctccgc ccgcctctcc ccctgccgct cccgtaccgc tcccccactg
    10801 ctcgctactg ctcgcccagc ggattgaccg gcgtgggcgg tgcgtccggg tcgtcctcgg
    10861 cgcgggggag cgggcggtga ccctccgacc agtggttgga ccagccgcag accccgcacg
    10921 agtaccgccc gtccagcccg gccagctccg taccgcaccg cttgcactgc gtgtacgtga
    10981 tgtccggcgt cgggggcggc atcggcgtcg gcttcggcac cgtccccgga acggcccccg
    11041 gcacggcccc ggggacggct gccggaaccg gcgcggcctc atgcggccgt tccggctcgg
    11101 gcggccgttc cgcctcgggc gcggggatgt cactcatgcg tcggagcgta cgcccgcgcg
    11161 ggagtgacac ggctcacgta cacccgtcgc accacccgga ccggcaggtg gcgcccggta
    11221 tgcgggtggg cgcggtcgat atctgtcatc cgttttctgt tatccgccga ccgtcaccct
    11281 gttctcctct ccgtcgggtc agttaggttc ggtgctccgg gagagtggac gaggcgtgat
    11341 cagtgaacag atagccgcgg tggtcgtcgc ggcccgggac ggggatcagc gggcgcgcga
    11401 cgagctcgtc gccgggtatc tgccgctcgt gtacaacatc gtcgggcggg cgctgggcgg
    11461 gcacgccgac gtcgacgacg tcgtgcagga gagcctgctg cggatgctcg acgggctcgg
    11521 ctcgctgcgc gagcccgcgg ccttccggtc gtggctcgtc gccgtcacca tgaacgagat
    11581 ccgccggtac tggcagggcc accgccgcac ccccgtcgac ggcgggctcc aggacgccca
    11641 cgacctggcc gacccgggcg ccgacttcgt cgatctcacc atcgtgcggc tcggcctgtc
    11701 cgggcagcgc aaggaggtca ccgaggccac ccgctggctg gagcccgacg accgggcgct
    11761 gctctcgctg tggtggctgg aggcggcggg cgtactcagc cggggcgagg tcgcctcggc
    11821 gctcgacctg agcgccgagc acgccgccgt acgcgtccag cgcatgaagg gccagctgga
    11881 gaccgcccgg gtcgtcgtgc gggcactggc cgggatcgag cgctgtggcg agctgtacgg
    11941 gctcgccctg tcctgggacg gcgtgccgtc ggccctgtgg cgcaagcgca tagcccgcca
    12001 tgcccgtacc tgcgcggtct gctccgggca ctggagcggg ctcatacccg ccgaggggct
    12061 actcgtcggg ctcgccctgg tcccggtggg agcggccacc gccggtctgc tggcggttct
    12121 gggcggccgg gcgcccgccc tggagaccac cgcccacgcg accgccgcca cccagccctc
    12181 tcctcgcgcc gcgcacggcg cccacgccgc gggccggcgg cgggcccccg cctcccgacg
    12241 cgaccggcgc gaccggcgga cgcggcgacg gcgccgggcg gccgccgtca tcgccgggct
    12301 cgccgccgtc gcggccctcg gcggtgccta ccgcttcgtc accgaccccg gccaggactc
    12361 gtcccggacc gtcgcggacg cccctctcac caccaccgac gccgccagcg ccgacggcct
    12421 cagcaccggg cccctgtcac cgagcccgtc cgcctccaac tcccctacca aggcgagcag
    12481 ttcgccgtcg ccgagcgccc cggtcaagca ctcctccccg cccccggcca ccaagtcgcc
    12541 cacgcacgcc gcaccgccca ggcccgcgcc cagcaccaag cgggcggcgg ccggcccgga
    12601 cgacggcaca ccggccgccg tgcagcaggt gctcgatctc gtcaactccg agcgcagcaa
    12661 ggcgggttgc tcggcgctca ccagcaatcc gaagctctac gacgccgccc tcaagcactc
    12721 cgagaacatg gccgcgcaga acttcttcga ccacaccgac cccagcggtg cgggccccgg
    12781 cgagcgcatc acggcagccg ggtaccagtg gagttcgtac ggcgagaaca tcgctcgggg
    12841 ccaggcggac gcggccgccg tcatggactc ctggatgcac agccccggcc accgcgccaa
    12901 catcctgaac tgcgggtaca aggagatcgg catcggtgtg cactacgggt ccggcggccc
    12961 ctggtggacc caggacttcg gcacccggag ctgataccgc cgacgtacgg gggcgggccc
    13021 ggtcttcgcg accgggcccg cccctgtgcg tccgtacgcc gttcctaccc gttcagtcct
    13081 ggtcctccag gtcgccctcg gtctccaggt agacctgccg cagcgcttcg agcacggccg
    13141 ggtcgg
//
