LOCUS       NZ_CP070373            20954 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5675910
            Orig. end                         :: 5696864
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="32"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20954
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10954](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    275..290
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.33"
                     /tool="antismash"
     misc_feature    complement(319..335)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.0"
                     /tool="antismash"
     misc_feature    996..1010
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.23"
                     /tool="antismash"
     misc_feature    1253..1268
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.23"
                     /tool="antismash"
     gene            complement(1369..1881)
                     /locus_tag="GWQ54_RS25030"
     CDS             complement(1369..1881)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639523.1"
                     /locus_tag="GWQ54_RS25030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_167155295.1"
                     /transl_table=11
                     /translation="MTTQLTAPADRVLRAAPDNPVLRVAPAAPADAAAHFRASLVFHAD
                     VSDVAAALATGGDPGFVVLDSRSTESWDQGHVPGAVHLPTALIAEQAERLLDKSVPVVA
                     YCWGPGCNGATRAALALAELGFRVKEMLGGFEYWVREGFAFETWEGSGHRAADPLTAPA
                     GAVECGC"
     misc_feature    1972..1983
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            1976..2422
                     /locus_tag="GWQ54_RS25035"
     CDS             1976..2422
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140508.1"
                     /locus_tag="GWQ54_RS25035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_161251018.1"
                     /transl_table=11
                     /translation="MNAYSPDATDWRILEALQEQGRATFAELARTVSMSASAVTERVRR
                     LEEAGVIAGYTAVVDQERLGRPILAFVRLRYPNGNYKPFHDLVEATPEIMEAHHVTGDD
                     CFVIKVNARSMSHLEEISGRIGTLGSVTTSVVYSSPLPRRAIGH"
     gene            complement(2387..5434)
                     /locus_tag="GWQ54_RS25040"
     CDS             complement(2387..5434)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1218: Exonuclease"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522768.1"
                     /locus_tag="GWQ54_RS25040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SMC family ATPase"
                     /protein_id="WP_167155292.1"
                     /transl_table=11
                     /translation="MRLHRMRVTAFGPFAGGQEVDFDALSTAGLFLLHGPTGAGKTSVL
                     DAVCFALYGAVPGARQSPGTPLRSDHAAPDVFTEVLLELTVGGRRLEVTRRPQQDRPKK
                     RGSGFTTEKAQTWLREYDPAEGAWRALSRSHQEIGEELGRLLGMSREQFCQVVLLPQGE
                     FAKFLRSDAEARGKLLGRLFDTRRFAAVEDRLAELRRTAERQVKEGDERLLALAQRMAQ
                     AAGGGAEARAWPLPDARPGDPGLASAVLQWAAVARSAAHERLDIASAAVAAAESRQASA
                     RRLAEEARQLAELQARYAEARAGAEELAAGQPEQDELKARLETARKAERVAPALEWREQ
                     AQRAHRTATAERDRSRERLHPDLADAGADQLAALERRMRQDLGALESARRAERRSTEID
                     EERSRLDRQSRADEDVLTDTAAWLAGWETARLGHQTRIDNAHEAATRAEHLAGQLEPAR
                     RRFAAARERDALEARLSEAARRHEDARAAANAAHERWLTLREERLRGIAAELAARLQDG
                     EPCTVCGSAEHPAPARPGTGQVDRATEDAAQQAHRRSESLRAEAEAALSSVREDIAGAR
                     AEAGTASVAELADAATELENEHRAARDAAGGLHEARLALASAEREYEQRLAAQRAAQQK
                     IAARTASREALDREQAALESELSEVRAGAASVAEQAGLLEHRAAILAEAAEAVRAVEDS
                     AARLKEADGRLSEAAFRAGFDTPAAASAAQVDERGQRDIQHRLDAWQQRKATIGARLAE
                     PETAAAGRAAPARTEETAAASAAAERALRDAASALAAARARCAELRALSVRAAEETRAL
                     GPLREEYERVASLAGLTAGTSADNERKMRLESYVLAARLEQVAAAATARLQRMSGGRYT
                     LVHSDVRGGRGRSGLGLHVVDAWTGRERDTATLSGGETFFASLALALGLADVVTDEAGG
                     ARLDTLFIDEGFGSLDDQTLDEVLDVLDSLRERDRSVGIVSHVGDLRRRIPAQLEVVKD
                     RAGSSVRLRGIDGAGSMADRAPGQRG"
     gene            complement(5431..6585)
                     /locus_tag="GWQ54_RS25045"
     CDS             complement(5431..6585)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230: Nuclease SbcCD,
                     D subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970568.1"
                     /locus_tag="GWQ54_RS25045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="WP_167155289.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.8e-07, bitscore:
                     30.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFLHTSDWHLGRSFHRVDLLGAQAAFVDHVVATVRDRGVDAVLV
                     AGDVYDRAVPPLAAVDLFDRALHRLADLGVPTVMISGNHDSARRLGVGAGLIERAGIHL
                     RTDPAGCGTPVMIGDVACYGLPYLEPALVRDELAAPKAGHEAVLAAAMERVRADLATRP
                     AGTRSVVLAHAFVAGGEPSDSERDITVGGVAAVPAGVFDGVDYVALGHLHGSQTITERV
                     RYSGSPLAYSFSEATHRKSMWLVDLAADGAVAAERIDCPVPRPLARVRGRLDELIEDPA
                     LARHEQSWVEATLTDAVRPADAMARIAARFPGTLSLVFDPERADGDPHASYAQRLSGRS
                     DQQIAEDFVAHVRGGSGPDDRERTVLQGAFDAVRVDDGVHEVAR"
     gene            complement(6753..7379)
                     /locus_tag="GWQ54_RS25050"
     CDS             complement(6753..7379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948434.1"
                     /locus_tag="GWQ54_RS25050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YigZ family protein"
                     /protein_id="WP_167155286.1"
                     /transl_table=11
                     /translation="MQEQYRTVAREGVHESEINRSRFLCALAPAATEQEAQDFVARVRK
                     EHPTASHNCFAYVIGADASVQKASDDGEPGGTAGVPMLQMLTRREVRYAVAVVTRYYGG
                     VKLGAGGLIRAYGGVVGEALDEIGTVVRRRFRLATVTVDHQRAGKLENDLRATGRAVRE
                     VRYAESVTIGLGLPEADVDAFRSWLADATAGTATLELGGEAYGDA"
     gene            complement(7449..9520)
                     /gene="fusA"
                     /locus_tag="GWQ54_RS25055"
                     /pseudo=""
     CDS             complement(7449..9520)
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fusA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123848.1"
                     /locus_tag="GWQ54_RS25055"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="elongation factor G"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTNRPNPAATCLSAVRNLGILAHVDAGKTTVTERILFATGAVHK
                     RGEVHDGTTVTDFDAQERDRGITIFAAAVSCDWDGHRINLIDTPGHVDFADEVERSLRV
                     LDGAVAVFDAVAGVEPQSESVWRQADRHGVPRIAFVNKLDRAGADLDTAVASIRDRLGA
                     VPLVVQLPVGREDDFTGVIDLVRMRTLMWHDDLCTAGPVDAALLDEATRRRRLLEETVA
                     ELHPDALEEFCAASALTEETLERALRELTLNGDAVVVLCGSAYRNRGIEPLLDAVVAYL
                     PSPADLPPVRGAGEDAGAERAPDPAEPFAALAFKVNATERGRLTYLRIYSGTLRKGDSV
                     RDAASGRVERVGRILRVQADRHEEREEARAGDIVAVVGLKVPRPGATLCAPEAPVLLEP
                     PSVADPVVSVAVEAGRGTDPGRLSAALARLAEEDPSLVVRTDPETGQTVLSGLGELHLE
                     VAVEKIRRDRGVTVNVGRPQVSYRETVVRGVTGLVYRHVKQDGGAGQFAHVVLDVEPMA
                     EGGFAFRSTVVGGRVPQEYARAVEAGCRDALAEGPLGGHPVTGLRVTLTDGATHSKDSS
                     EMAFRAAGRFALREALRVSAMGLLEPVAEVTVTVPEDGVGGVLGDLAARRGQVSASTAA
                     PVPGRR"
     misc_feature    9622..9638
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            10001..10954
                     /locus_tag="GWQ54_RS25060"
     CDS             10001..10954
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174221.1"
                     /locus_tag="GWQ54_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_167155283.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.8e-26, bitscore:
                     90.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4e-13,
                     bitscore: 48.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAWNQARDAAGIHDPGLRDDYTRQRELTARFKRSAYLAARLLLP
                     RPLFPHVMAMTAFMHHSDNLLDSGAREGRAAAYDAWERQVRAALATGESGHPVLRPVLH
                     TLVAHPRLRGHIEEYLVTARADLDFAGFATEADHQAYVDAYSLPAFLLVACLIAPDGDG
                     TEFRAACRTFIDAGQRLDFVNDLAEDLADGRLTIPRETLARHGVTREDLEQARDLPGTR
                     ELITAVLGQARATLADSRPLVTIVPAPGRPLVRALISFDELTATAAARKGAGLLTAPAR
                     PSAPGAARVLLREYARARRLRCAGAGGTRPGLRPRP"
     gene            11085..11492
                     /locus_tag="GWQ54_RS25065"
     CDS             11085..11492
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988444.1"
                     /locus_tag="GWQ54_RS25065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CoA-binding protein"
                     /protein_id="WP_161245622.1"
                     /transl_table=11
                     /translation="MYADQDTIRTILTDTGDTWAVVGLSNNRNRAAYGVAEVLQRFGKR
                     IVPVHPKAETVHGEQGYASLDAIPFPVDVVDVFVNSELAGAVADQAVAVGAKAVWFQLG
                     VVDEAAYERTRDAGLAMVMDRCPAIEIPRLR"
     gene            11592..12455
                     /locus_tag="GWQ54_RS25070"
     CDS             11592..12455
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-273). E-value: 9e-24.
                     Score: 76.3. Matches aSDomain:
                     nrpspksdomains_GWQ54_RS25070_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884104.1"
                     /locus_tag="GWQ54_RS25070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_189764723.1"
                     /sec_met_domain="PF00561 (E-value: 4.6e-20, bitscore: 71.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.5e-12, bitscore:
                     46.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGELIRTRDGRDLGVESYGNPKGRPVFLLHGTPGSRLGPAPRSAV
                     LYRLGVRLITFDRPGYGDSDRLPGRRVADAAADVEAIADALDLDEFAVVGRSGGAPHAL
                     ACAALLPDRTARVAGLVSIAPRDAQGLDWFEGMTESNVREYINAAAGKGQLTTALEMRS
                     ITIRSDPRRSVDDMRHRLPKPDRGIVADAGIRAMLERNFEEGLRSSADGWVDDVMAFST
                     DWDFRLEDITAPVLLWHGEQDVFAPVQHTRWLAERIPGAQLVVERGAAHFGALRVLTRV
                     LSWATW"
     misc_feature    11628..11630
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        11664..12410
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GWQ54_RS25070_Abhydrolase_1.1"
                     /evalue="9.00E-24"
                     /label="GWQ54_RS25070_Abhydrolase_1.1"
                     /locus_tag="GWQ54_RS25070"
                     /protein_end="273"
                     /protein_start="24"
                     /score="76.3"
                     /tool="antismash"
                     /translation="PVFLLHGTPGSRLGPAPRSAVLYRLGVRLITFDRPGYGDSDRLPG
                     RRVADAAADVEAIADALDLDEFAVVGRSGGAPHALACAALLPDRTARVAGLVSIAPRDA
                     QGLDWFEGMTESNVREYINAAAGKGQLTTALEMRSITIRSDPRRSVDDMRHRLPKPDRG
                     IVADAGIRAMLERNFEEGLRSSADGWVDDVMAFSTDWDFRLEDITAPVLLWHGEQDVFA
                     PVQHTRWLAERIPGAQLVVERGAAHFG"
     gene            complement(12524..16498)
                     /gene="fxsT"
                     /locus_tag="GWQ54_RS25075"
     CDS             complement(12524..16498)
                     /codon_start=1
                     /gene="fxsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119569.1"
                     /locus_tag="GWQ54_RS25075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxSxx-COOH system tetratricopeptide repeat
                     protein"
                     /protein_id="WP_167155280.1"
                     /transl_table=11
                     /translation="MTENRNGTVVTFYSYKGGTGRTMALANCAWILAANGYRVLAVDWD
                     LEAPGLHRFFHPFLDLADLEATPGLINLITDYQDEARRPADREPDWHREYARVRPHATS
                     LNWNFPQGGSLDFLSAGRRNRDYPSIVGKMDWDDFHERFGGGQFFDAMRDDMQRHYDYT
                     LIDSRTGLSDIADICTVQMPEVLVVCFTLSDQSIDGASAVARDIEERYHERRIRILPVP
                     MRIDDGEKEKADAGRALARESFPGFPSGLSPEELGNYWGTVEVPYRPFYAYEEILATFG
                     DAPNVSSSMLSACERLTSVLTGGLVNSLPPMDEADRLTHVAAYTRRRPMPPSNLVLTHV
                     AEDQMWVDWLVHVLTVAGFHVVPVDVRAPQTGTPEIEFTTGIGYRVIPIVSQAYLNSER
                     ARSSWETGSGLDAAGVRRHILPVRVGDVRLSPPLSNRGVIDLVRLDENDAAAAVLNALD
                     RSEAVAAFASAPAGPRYPGSVPKVWNVRPRHAWFTGRTTVLEKLRDQLRGDSRSAQRFP
                     QVLYGLGGVGKTQVAREYAHRFRADYDLVWWIEAEQPDRVVSSLAELAAEMDLRAGDVV
                     AEAAAAALQALRRGAPYSRWLLIFDNVEDLDRALKLLPEEMEPIAGETYGHILATCRNK
                     PASTKVEGIEVEVFTRAESIEHLCRRVTKLPVADADRVADAVGDLPLAVEVAAAWLAET
                     ATPVDAYVEQLREQSTKVLSLGKPEDYSEQIGATWNISISRLRDESKAAVRLLELCSFF
                     SAEPISMRLIGSDSMFESLLPYDPDLRERYMLGKVIQTLNRFALAKVDPADSSIQVHRL
                     VQAAVRAGLTEEEVDTAKHEVHRILAEARPVEGVDRDNPVNDPKSWPSFELIWPHLSAS
                     GIADCDEEKVRQLMVDRIRYLLKRGELESARVLGTQLNKVWTRELGENDLQTLNIRFEL
                     ANALRAQGKYQEARAMDEDTLARQISVLHKDHPNDDHPSILITTGSLAADLRALGRFDE
                     ALTRDLRIYHGLRQIFGENHPRTLIAANNLAIDYRLSGDSEAARRLDEETVERRSALLG
                     EEHPFTLTTKGHLARDLRESGEYAASIQVLRAVVAAFERVLNADVPEALRTAKSLAVSL
                     RKAGHPHEAKRLTEETYNRYRGRYGTKAPDALACCLNLAADFSATGDKQAALDLALQAY
                     EGYQSTLGEEHPFTLACRNNLYIYQRGLGAAEEAARGGEDVRAALEEVLGSRHPFTLCA
                     AINLANAYGDLGRPDLAERWERTALKGLLERFGPTHPDVLACRSNLAITLRAAGREEEA
                     QRLRASILEPAAKQLGVDHPIAEAARAWRRINRDLEPQPV"
     gene            complement(16491..17837)
                     /locus_tag="GWQ54_RS25080"
     CDS             complement(16491..17837)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326098.1"
                     /locus_tag="GWQ54_RS25080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIR-like protein FxsC"
                     /protein_id="WP_229861393.1"
                     /transl_table=11
                     /translation="MQGSVGAGGDEQKPYFFLSYAHTPKSDPKDKDPNLWVQRFFRDLC
                     AHVMQLTPLPAGSAGFMDQQMQPGEGWQERLSEALAYCKVFVPLYSPRYFLSEQCGREW
                     FAFSSRAASQNTRHSNNNSNPVTGIVPALWVPVPTRQLPQPAERLQFNHATFGDEYADE
                     GFYGLIKLNYLRDQYERAVYRLAKRIVNVAQQAQLEHGDPHQDYAKVPPAFGPTGGPAR
                     EMEVSVLACSRSSLPTGRSPDCYGTEALDWNPYHPASSRPLADHTVDVVRNLNYTVHLS
                     DFEAEPQRLLASGPPGPGLLLLDRWALDARRRRELLDQLGATRRPWISVMVPGNVADAE
                     THARNEELSQHTDAALAARVDESDGHRTPSAGLPTLEAFSKAIPGAVKAAVKHYEANAP
                     TYPPPGSGGPMPRVLPSGIGYGAGGPSGRGQSTDQDKNHGDKAEGSSDD"
     gene            complement(18028..20457)
                     /locus_tag="GWQ54_RS25085"
     CDS             complement(18028..20457)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SAM_SPASM_FxsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134075.1"
                     /locus_tag="GWQ54_RS25085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxsB family cyclophane-forming radical SAM/SPASM
                     peptide maturase"
                     /protein_id="WP_167155277.1"
                     /sec_met_domain="PTHR43273 (E-value: 4.4e-68, bitscore:
                     228.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="SAM_SPASM_FxsB (E-value: 2.9e-176,
                     bitscore: 584.5, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.6e-14, bitscore: 51.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRPIPPALSQFVLKVHSRCDLACDHCYVYEHADTSWRGRPRAVS
                     EEILAQVANRIAEHARRHRLPTVHVVLHGGEPLLAGPDRLRRAAEELRRALHGVSALDL
                     RMHTNGVLLDEAFCELFLELGIKVGVSLDGDKVSNDRHRRYADGRSSHAKVIRAVELLQ
                     RPRYRRLFAGLLCTIDVENDPVAVYDALVELSPPRIDFLLPHATWDTPPPRPGGAATPY
                     ADWLDAIYRRWDAAGRPVPVRIFDSVLRTLRGESSLTESLGLAPADLVVIETDGTFEQA
                     DSLKTSYDGAPATGMDVFTHSLDDVLQHPGMLARQQGIEQLCRQCRDCPVVQSCGGGLY
                     AHRYRSDGSEFDNPSVFCPDLLALVTTIRDREAEVPAPKASSAELPLEQADFEELATGF
                     GGADTVTRLAAAQLDINQELLAAVSEQRIALSDREGAAAWDLLTQLDAEVPDELAGVLV
                     HPYTRPWALGVLEGRVAPAAGLAEIAAATTLRARLDRTVTVPLRDGMLRLPGLGTVRLD
                     SSAGHAEVTAGAEGFTVRAGARGLDIGWHEGMDGLTPHWHPVRLFAGEGWSVAIEDTDP
                     LRDCHEWPVAARLAADEAKLWSEDLTGAWSLIRRELPAYADGVAAGLRLITPLHAPDGS
                     DVSAACKDAWGAIGVARPASPEQLALLIVHEFQHVKLAAVLDAVDLYDKADRDRYYAPW
                     RADPRPIGGLLQGTYAHIAVTDFWRVRRETAGTGPERALAEAEFARWRQQTAEAVDVLL
                     GSASLTDLGQRFVGRMGETVSGWRGEAVSPAALTAAQDSARRHRAAWKARVEGGAE"
     gene            complement(20478..20669)
                     /locus_tag="GWQ54_RS25090"
     CDS             complement(20478..20669)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS25090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_161245620.1"
                     /transl_table=11
                     /translation="MDALVSAAVRPGPALHRPALPWLPLVRRAAAQGAGRAPANLTRVM
                     AAYGSPTVPAASAFQSAL"
ORIGIN
        1 gcgctcgcct cccggctgcg cgcggtgccc gccgccctgg agggttaccg ggcctcgctc
       61 gaactgggcc tggagcgcaa gctgttcggc ggcccgcgcg ccacggagac ggtcgtcggg
      121 cagctcggcg agtgggtcga caccggcttc ttcgagggac tcgccgccgc cggccccgag
      181 tccctgcgca ccggactcga caccgccgcc gccgaggcga ccgccgccct caccgcgctc
      241 cgcgactggc tgcgtgacgt gtacgcgccc ggcatcgaag gcgcgtccga cacggtgggc
      301 cgcgagcgct accagcgctg gtcgcagtac tacaacggca ccgcgctcga cctggacgag
      361 gcgtacgcct acggctggtc cgagtaccac cggctgctcg gcgagatgaa gaccgaggcc
      421 gccaagatcc tgcccgacgc cgggccctgg gaggtgctcg cccacctcga cgagcacggc
      481 gcgcacatcg agggcgtcga cgaggtccgc gactggctgc aggccctgat ggacgaggcc
      541 atcgaggcgc tcgacggcac ccacttcgaa ctcgccgagc gcgtacgaaa ggtggagtcc
      601 cgcatcgcgc cgcccggcgg cgccgcggcc ccgtactaca cgggcccctc cgaggacttc
      661 tcgcgccccg gccgcacctg gctgcccacc atgggcgaga cccgcttccc ggtgtacgac
      721 ctggtgtcga cctggtacca cgagggcgtg ccgggccacc acctccagat cgcgcagtgg
      781 gtgcacgtcg ccgaccagct ctcgcgctac caggcgacgg tcggccaggt cagcgccaac
      841 gccgagggct gggccctgta cgcggagcgc ctgatggacg agctgggctt cctcaccgac
      901 cccgagcgcc gcctcggtta cctggacgca cagatgatgc gcgcctgccg ggtgatcatc
      961 gacatcggca tgcacctgga gctggagatc ccggcggact cgccgttcca cccgggcgag
     1021 cgctggacgc cggagctggc ccacgcgttc ttcagcggtc acagcagcag gccggccgac
     1081 ttcgtccaga gcgagctgat ccgctacctg tcgatgccgg ggcaggcgat cggctacaag
     1141 ctgggcgagc gcgcctggct gctcggccgg gcgaacgcgc aggcccgcca cggtgacgcc
     1201 ttcgacgcga aggcctggca catggcggcc ctctcgcagg gttccctcgg cctcgacgac
     1261 ctggtcgacg agctctccaa gctctgaggt cgcggcgggg gcgacccgtt caacgggccg
     1321 cccctacaag ggagttcggg ggtcaccgcg ctcgggccgc gcaggagttc agcagccgca
     1381 ctcgaccgcg ccggccggcg cggtcagcgg gtcggcggcg cggtgcccgc ttccctccca
     1441 cgtctcgaag gcgaagccct cgcgcaccca gtactcgaag ccgcccagca tctccttgac
     1501 ccggaagccg agttcggcga gggccagggc ggcgcgggtg gcgccgttgc agccggggcc
     1561 ccagcagtag gcgaccacgg gcacggactt gtccaggagc cgctcggcct gttcggcgat
     1621 cagcgcggtc ggaagatgga cggcgccggg cacatggccc tggtcccagg actcggtgga
     1681 gcgggagtcg aggacgacga agccggggtc gcccccggtg gcgagagccg cggccacgtc
     1741 ggagacgtcc gcgtggaaga ccagggaagc acggaagtgg gcggcggcgt cggccggagc
     1801 ggccggggcc acccgcagga ccgggttgtc cggggccgcg cgcaggactc ggtcggcggg
     1861 ggcggtgagc tgtgtcgtca tggctgaaaa tctaggcgcg ggtgatccac gacggaagga
     1921 acgatcctcg gggcaaccct tgatccgccg gggatttcac ggttgtgtgg gcgacatgaa
     1981 cgcgtattcc ccggacgcca ccgactggcg catattggaa gccctgcagg agcagggccg
     2041 ggccaccttc gccgagctgg cccggaccgt ctcgatgtcg gccagcgccg tcaccgaacg
     2101 ggtgcgccgc ctcgaagagg ccggggtgat cgcgggctac accgcggtcg tcgaccagga
     2161 acgcctgggc cgcccgatcc tcgccttcgt gcggctgcgc taccccaacg ggaactacaa
     2221 gccgttccac gatctcgtgg aggcgactcc ggagatcatg gaggcccacc acgtcacggg
     2281 tgacgactgc ttcgtcatca aggtcaacgc ccgctcgatg agccacctgg aggagatctc
     2341 cgggcggatc ggcacgctgg ggtccgtcac gacgagcgtg gtctattcat cccctctgcc
     2401 ccggcgcgcg atcggccatt gagccggccc cgtcgatccc gcgcagccgc accgacgacc
     2461 ccgcgcggtc cttcaccact tccagctggg cggggatgcg ccggcgcaga tctcccacat
     2521 ggctcacgat gcccacgctg cggtcgcgtt cgcgcagcga gtccagtacg tcgaggacct
     2581 cgtccaaggt ctggtcgtcg aggctgccga agccctcgtc gatgaacagg gtgtccaggc
     2641 gcgcgccacc cgcctcgtcc gtgacgacgt cggcgaggcc gagggccagg gcgagggagg
     2701 cgaagaacgt ctccccgccg gacagtgtcg ccgtgtcccg ctcccggccg gtccaggcgt
     2761 ccaccacgtg caggccaagg cccgagcggc ccctgccgcc ccggacgtcg gagtggacca
     2821 gggtgtagcg gccgcccgac atgcgctgga gcctggcggt ggccgcggcc gccacctgct
     2881 ccagacgggc ggcgaggacg tacgactcca ggcgcatctt gcgctcgttg tcggcggagg
     2941 tgcccgcggt gagcccggcc agggacgcca cccgctcgta ctcctcgcgc agcggaccga
     3001 gcgcccgggt ctcctcggcg gcccggacgc tcagtgcgcg cagttccgca cagcgggccc
     3061 gggccgccgc gagggcggac gccgcgtccc gcagcgcgcg ttcggccgcg gcggaggcgg
     3121 ccgccgtctc ctcggtgcgg gccggtgcgg cccggcccgc ggcggccgtc tccggttcgg
     3181 cgaggcgtgc gccgatggtc gccttccgct gctgccaggc gtcgagccgg tgctggatgt
     3241 cccgctggcc gcgctcgtcg acctgggcgg ccgacgccgc ggcgggggtg tcgaagccgg
     3301 cccggaacgc cgcttccgag agccgcccgt cggcctcctt gagccgcgcg gcactgtcct
     3361 cgacggcgcg gaccgcctcc gcggcctcgg cgaggatggc ggcgcggtgt tcgagcagac
     3421 cggcctgttc cgcgacgctg gccgcgcccg cccgcacctc gctcaactcg ctctccagcg
     3481 ccgcctgttc acgatcgagg gcctcgcggc tcgcggtgcg ggcagcgatc ttctgctggg
     3541 ctgcgcgctg ggccgcgagg cgctgctcgt actcccgctc cgccgaggcg agcgcgagcc
     3601 gggcctcgtg cagccctccc gccgcgtccc gcgccgcacg gtgttcgttc tccaactcgg
     3661 ttgcggcgtc ggccagttcg gccacgctcg cggtgcccgc ctcggcgcgg gcgcccgcga
     3721 tgtcctcccg caccgaggag agggctgcct ccgcctcggc ccggaggctc tccgaccgtc
     3781 ggtgggcctg ctgcgcggcg tcctcggtgg cgcggtcgac ctgcccggtg ccggggcgcg
     3841 cgggcgcggg gtgctccgcc gagccgcaca ccgtgcaggg ctcgccgtcc tggagacggg
     3901 ccgccagctc ggccgcgatg ccgcgcagcc gctcctcgcg cagcgtcagc caccgctcgt
     3961 gcgcggcgtt ggcggccgcg cgggcgtcct cgtgccgacg cgcggcctcg ctcaggcggg
     4021 cctccagcgc gtcgcgttcg cgggcggccg cgaagcggcg ccgggccggc tccagttgtc
     4081 cggccaggtg ttccgcgcgg gtcgccgctt catgagcatt gtcgatccgg gtctggtggc
     4141 cgagccttgc ggtctcccag cccgcgagcc aggccgcggt gtcggtgagg acgtcctcgt
     4201 cggcgcggga ctgccggtcc aggcgggagc gctcctcgtc gatctcggtg ctgcggcgct
     4261 cggcccggcg ggctgattcc agcgcgccga ggtcctggcg catccgccgc tccagggcgg
     4321 cgagttgatc ggctccggcg tccgccaggt ccgggtgcag ccgctcgcgc gagcggtccc
     4381 gttcggcggt cgcggtgcgg tgggcccgtt gggcctgctc ccgccactcc agggcgggcg
     4441 cgacccgttc ggccttgcgg gccgtctcca ggcgggcctt cagttcgtcc tgctcgggtt
     4501 ggccagcggc caactcctcg gcgccggcgc gcgcttcggc gtaccgcgcc tggagttcgg
     4561 ccagctgccg ggcctcttcg gcgaggcggc gggcggacgc ctgcctgctc tcggcagcgg
     4621 cgaccgcggc cgaggcgatg tcgaggcgtt cgtgtgccgc gctgcgcgcg acggccgccc
     4681 actgcaggac cgcggaggcg agtcccgggt cgccgggccg tgcgtcgggc agcggccagg
     4741 cgcgtgcctc cgcgccgccg cccgcggcct gcgccatccg ctgggcgagc gcgagcagcc
     4801 gctcgtcgcc ctccttgacc tggcgttccg cggtcctgcg cagctctgcg aggcggtcct
     4861 ccacggcggc gaaccgccgg gtgtcgaaga gcctgccgag cagcttgccg cgcgcctcgg
     4921 catccgacct gaggaacttg gcgaactcgc cctgcggcag caggacgacc tggcagaact
     4981 gctcccggct catcccgagg agccggccga gctcctcgcc gatctcctgg tgcgagcggc
     5041 tgagcgcccg ccaggctccc tcggccgggt cgtactcgcg cagccaggtc tgcgccttct
     5101 cggtggtgaa gccactgccg cgcttcttgg gccggtcctg ctgcgggcgg cgggtgacct
     5161 ccaaccgccg cccgccgacg gtcagttcga gcagcacctc ggtgaagacg tccggcgcgg
     5221 catggtcgct gcgcagcggt gtgccagggc tctggcgggc gccgggcacg gctccgtaca
     5281 gggcgaagca gaccgcgtcg agcaccgagg tcttgccggc gcccgtcggg ccgtgcagca
     5341 ggaagagccc cgccgtggac agcgcgtcga agtcgacctc ctggccgccc gcgaaggggc
     5401 cgaaggcggt gacgcgcatg cggtgcagtc tcacctggcc acctcgtgca ccccgtcgtc
     5461 cacccgcacg gcgtcgaacg ccccttgcag gacggtccgt tcgcggtcgt cggggccgct
     5521 gccgccgcgt acgtgggcca cgaagtcctc cgcgatctgc tggtcgctgc ggccgctgag
     5581 ccgttgcgcg tacgaggcgt gggggtcgcc gtccgcccgc tccgggtcga agacgaggct
     5641 gagggtgccc gggaagcgtg cggcgatccg ggccatggcg tcggccgggc gcaccgcgtc
     5701 ggtcaacgtg gcctccaccc aggactgttc gtgccgggcc agggccgggt cctcgatgag
     5761 ctcgtcgagc cggccgcgga cgcgggcgag cgggcggggc accgggcagt cgatccgctc
     5821 ggccgcgacg gcgccgtcgg cggcgaggtc gaccagccac atggacttgc ggtgcgtggc
     5881 ctcggagaag gagtaggcga gcggcgagcc cgagtagcgc acccgctcgg tgatcgtctg
     5941 gctgccgtgc aggtggccga gggccacgta gtccacgccg tcgaagacgc ccgcgggcac
     6001 ggcggccact ccgcccacgg tgatgtcccg ctcactgtcg ctcggctcgc caccggcgac
     6061 gaaggcgtgc gcgaggacga cggagcgggt gcctgcgggg cgggtcgcga ggtcggcccg
     6121 cacgcgctcc atggccgcgg cgagcacggc ctcgtggccg gccttcggcg cggccagttc
     6181 gtcgcggacc agggcgggct ccagataggg cagcccgtag caggcgacgt caccgatcat
     6241 gacgggggtg ccgcagcccg ccgggtcggt gcgcaagtgg atgcccgccc gctcgatcag
     6301 accggccccg acgccgagcc ggcgcgccga gtcgtggttg ccggagatca tcacggtcgg
     6361 cacccctaga tcggcgaggc ggtgcagcgc ccggtcgaag aggtcgacgg cggcgagcgg
     6421 gggcaccgcg cggtcgtaca cgtcccccgc caccagaacc gcgtccacac ctcggtcgcg
     6481 gaccgtcgcc accacgtggt cgacgaacgc ggcctgggca ccgagcaggt cgacccggtg
     6541 gaaggaccgg cccaggtgcc agtccgaggt gtgcaggaat ctcatgatcc tcgagggtaa
     6601 cggtggggta cgacagcccg ggcggcaacg gagacatcgt tccgttccga agacctcaca
     6661 cacccacccc ctttgtccct taagtcgctt tccgggggcg ccccgtgccg attccgggcg
     6721 tggcggacgc accgggatgc gtgctccaca cctcacgcgt ccccgtacgc ctcgccgccg
     6781 agctccaggg tcgccgtgcc ggcggtcgcg tcggcgagcc aggagcggaa ggcatcgacg
     6841 tccgcctcgg gcagaccgag gccgatggtc acggactcgg cgtaccgcac ctcgcgcacc
     6901 gcgcgccccg tcgcccgcag gtcgttctcc agcttgcccg cgcgctggtg gtcgacggtg
     6961 accgtggcga ggcggaacct ccggcgcacg accgtgccga tctcgtccag ggcctcgcca
     7021 accacaccgc cgtacgccct gatcagaccg cccgcaccca gcttgacccc gccgtagtaa
     7081 cgggtgacga cggcgacggc gtagcgcact tcgcgccggg tcagcatctg gagcatgggc
     7141 actccggcgg tgccgccggg ctcgccgtcg tcgctcgcct tctgcacgga ggcgtcggct
     7201 ccgatgacgt acgcgaagca gttgtggctg gccgtcgggt gttccttgcg gacgcgggcg
     7261 acgaagtcct gcgcctcctg ttcggtggcg gcgggcgcga gcgcgcagag gaagcgcgac
     7321 ctgttgatct cgctctcgtg cacgccctct cgggcgacgg tccggtactg ctcctgcatc
     7381 cgaccaccct atgcgcccgc gcgcgcccgc cccgccccgg cggaccgggg cggggcgggc
     7441 ggcggcggtc agcgcgccag gagcacgtcg gccaccgcgg ccggtaccgg cgcgagcggg
     7501 gcgggccggg tggtgaaggt gccccgcccc tgggtccggc cgcgcagccg ggaggcgtac
     7561 ccgaacagct cggccagcgg gaccgtcgcc gtgatcaccg ccgacccggc accggcgcgg
     7621 cggtggacgc cgacacctgg ccgcgccggg cggcgaggtc cccgaggaca ccgccgacgc
     7681 cgtcctcggg aacggtcacc gtgacctccg cgaccggttc gaggagtccc atcgcgctca
     7741 cccgcagcgc ctcgcggagc gcgaagcggc ccgcggcgcg gaacgccatc tccgaggaat
     7801 ccttggagtg ggtcgccccg tcggtgagcg tgacccgcaa cccggtgacc ggatggccgc
     7861 cgagcggacc ctcggccagc gcgtcacggc agccggcctc cacggcccgc gcgtactcct
     7921 gcggaacccg gccgccgacc accgtcgaac ggaacgcgaa tcccccttcc gccatgggct
     7981 cgacatcgag gacgacgtgc gcgaactgcc cggccccgcc gtcctgtttg acgtgccggt
     8041 agacgaggcc ggtcaccccg cgcaccacgg tctcgcggta cgagacctgt ggtcggccga
     8101 cgttgacggt cacgccccgg tcgcggcgga tcttctccac cgcgacttcc agatggagct
     8161 cgcccagacc cgagagcacg gtctgtccgg tctccggatc ggtccgtacg acgagcgacg
     8221 ggtcctcctc ggcgaggcgt gccagggccg cggagagtcg tcccgggtcg gtgccgcgcc
     8281 cggcctcgac cgcgaccgac accactggat cggccaccga gggcggctca aggagcacgg
     8341 gtgcttccgg tgcgcacagg gtcgcgccgg gccgcggcac cttgaggccc accaccgcga
     8401 cgatgtcccc cgccctcgct tcctccctct cctcgtgccg gtctgcctgc acccgcagga
     8461 tgcggccgac ccgctcgacc cggccgctcg ccgcgtcacg cacggagtcg cccttgcgca
     8521 gggtgcccga gtagatccgc agatacgtca ggcggccgcg ctcggtcgcg ttcaccttga
     8581 aggcgagcgc ggcgaacggc tcggccgggt ccggcgcccg ctccgctccc gcgtcctcgc
     8641 cggcaccgcg gaccggcggc agatcggcgg gcgagggcag ataggcgacc accgcgtcga
     8701 gcagcggctc gatgccgcgg ttgcggtagg ccgagccgca cagcaccacc acggcgtccc
     8761 cgttcaaggt cagctcgcgc agggcacgtt cgagggtctc ctcggtgagc gccgaggccg
     8821 cgcagaactc ttcgagcgcg tccggatgga gttccgcgac cgtctcctcc aggaggcggc
     8881 gccgtcgcgt cgcctcgtcg agcagcgcgg cgtcgaccgg tccggcggtg cagaggtcgt
     8941 cgtgccacat cagggtgcgc atccgtacca ggtcgatgac gccggtgaag tcgtcctcgc
     9001 gcccgacggg cagctgtacc accaggggga cggcgccgag ccggtccctg atcgaggcga
     9061 ccgccgtgtc gagatcggcg cccgcccggt ccagcttgtt cacgaacgcg atgcgcggca
     9121 cgccgtgccg gtcggcctgc cgccacaccg attcactctg cggctcgact ccggcgacgg
     9181 cgtcgaacac cgcgaccgcc ccgtcgagca cccgcaggga gcgttcgacc tcgtcggcga
     9241 agtcgacgtg acccggggtg tcgatcaggt tgatgcggtg cccgtcccag tcgcagctga
     9301 cggccgcggc gaagatggtg atgccgcggt cgcgctcctg cgcgtcgaag tcggtgacgg
     9361 tcgtcccgtc gtggacctcg ccccgcttgt gcacggcgcc ggtggcgaac aggatccgtt
     9421 cggtgacggt cgtcttgccc gcgtcgacgt gggcgaggat gccgaggttg cggacggcgg
     9481 agagacaagt ggcggcgggg ttgggcctgt tggtgcgcat ggccggaggc ctttcgagtg
     9541 ccttcgctga gccgggctca ggaagcagcg ggaaggtgac agcgcgatga ggggacggcg
     9601 tcagggcgct cggcgtacgt gtcgtgacac gacaacaagg ccgaggcgca aactttttga
     9661 cgttccgtca gtaaatgtcg aagacatgcg gtgaaggccg cgcagccgtc accgtgcgac
     9721 gcgagacacc aaaatcacgt cgtaccggct cgaaggggcg aagtcggcgg tgtgctgcgt
     9781 acgcatgtcc cgactcccct tctcctcgct cgttcgcccg tcacccgacg ggcggcgtca
     9841 cgcccggtcg gcgccgcaca gggcgagtgt agggagaggg gcggggtggg ggcatcgggt
     9901 tttccggcag cggttccgcc acggcggatt gccggcaacg gtcccgccgc gccgccgtga
     9961 tcaactgaag gtccgtatcc agaccccagg agaggcttcg atgagcgcgt ggaaccaggc
    10021 acgcgacgcc gcgggcatcc acgaccccgg gctgcgcgac gactacacgc gccagcgcga
    10081 actgaccgcc cgtttcaagc ggagcgccta tctggccgcc cgactccttt tgccgcggcc
    10141 gctgttcccg cacgtgatgg ccatgaccgc cttcatgcac cacagcgaca acctgctcga
    10201 cagcggcgcc agggaagggc gggccgcggc ctacgacgcc tgggagcgcc aggtccgcgc
    10261 cgctctcgcc accggcgaat ccggccaccc ggtgctccgc cccgtgctcc acacccttgt
    10321 ggcgcatccc cgactgcgcg gccacatcga ggagtatctg gtgaccgccc gcgccgacct
    10381 ggacttcgcc gggttcgcca cggaggcgga ccatcaggcg tacgtcgacg cctactcgct
    10441 gcccgcgttc ctgctcgtcg cctgcctgat cgcgccggac ggcgacggca cggagttccg
    10501 cgcggcgtgc cggaccttca tcgacgccgg ccagcgcctc gacttcgtca acgacctcgc
    10561 ggaggacctc gccgacgggc gcctcaccat cccccgcgag acgctggcgc gccacggggt
    10621 cacccgtgag gacctggagc aggcccgcga tctgcccggc acccgtgagc tgatcaccgc
    10681 tgtcctcggg caggcccggg ccaccctcgc ggacagccgg ccgctcgtga cgatcgtccc
    10741 ggcgccgggc cgccctctgg tccgcgcgct catctcgttc gacgagctca ccgcgacggc
    10801 cgcggcccgc aagggcgccg ggctcctgac ggcaccggcg cgcccctcgg cgccgggggc
    10861 cgcacgggtg ctgctgcgcg agtacgcgcg ggcccggcgg ttgcggtgcg cgggcgccgg
    10921 gggcacccgg ccggggctcc ggccgcgtcc atgaccccgc gcgcggaaca ggaatgccgt
    10981 cgcacatcgc cggtgttccc ccagtgacgt gggccgcggg gcgccaaccg cagaccgcgg
    11041 ccccacccac cgtggaccga ccgaggacac cccaggagac gcccgtgtac gccgatcagg
    11101 acaccatccg cacgatcctc accgacaccg gcgacacctg ggccgtggtc gggctctcca
    11161 acaaccgcaa ccgggccgcc tacggggtgg ccgaggtcct gcagcggttc ggcaagcgga
    11221 tcgtgcccgt ccaccccaag gcggagaccg tgcacggcga gcagggctac gcctccctcg
    11281 acgcgatccc cttccccgtc gacgtcgtgg acgtcttcgt caacagcgag ctcgccggag
    11341 ccgtggccga tcaggccgtg gccgtcggcg ccaaggccgt ctggttccag ctcggggtcg
    11401 tcgacgaggc ggcctacgag cgcacccggg acgcggggct cgccatggtc atggaccggt
    11461 gcccggcgat cgagatcccc cgcctgcgct gagccgatcc gggccccgcg cgcattcgac
    11521 gagtgcgggt atgtaccact gaatggcaca cgctcatact ggcgccaacc agacctagcg
    11581 ggaggcacca gttgggggag ctgattcgta cccgggacgg gcgggattta ggggttgaga
    11641 gctacgggaa cccgaagggc agaccggtgt tcctgctgca cggcacgccg gggagccggc
    11701 tcggtccggc cccccgcagt gcggtgctct accgcctcgg ggtccgtctg atcacgttcg
    11761 accggccggg atacggcgat tcggaccggc tgccggggcg ccgggtggcg gacgccgcgg
    11821 ccgatgtgga ggccatcgcg gacgccctgg acctcgacga gttcgccgtg gtgggacgct
    11881 ccggcggcgc cccgcacgcg ctggcctgcg cggcactgct cccggaccga acggcccggg
    11941 tggcgggcct ggtcagtatc gcgccgcgcg atgcgcaggg gctcgactgg ttcgagggaa
    12001 tgaccgagtc caatgtgcgc gagtacatca acgcggctgc cgggaaaggc cagttgacga
    12061 cggccctgga gatgcggtcg atcaccatcc ggtccgatcc gaggcgttcg gtggacgaca
    12121 tgcgccaccg tcttcccaag ccggaccggg gcatcgtcgc ggacgccggc atccgggcga
    12181 tgctggagcg caacttcgag gaagggctgc ggagttcggc cgacggctgg gtggacgacg
    12241 tgatggcgtt cagcaccgac tgggacttcc ggcttgagga catcaccgcg ccggtgctgc
    12301 tgtggcacgg cgagcaggac gtgttcgcgc ccgtccagca cacccgctgg ctggccgagc
    12361 gcattccggg cgcccagctg gtcgtcgagc ggggcgcggc ccacttcggg gcgctgcggg
    12421 tgctcacccg tgtgttgagc tgggccactt ggtgagtcac tgaggacacg gcgaacaggg
    12481 agtgcccggg cccgctgggc ccgggcactc ccccgtccgc gtctcacacc ggctgcggct
    12541 ccaggtcgcg gttgatccgg cgccaggcgc gggccgcctc ggcgatgggg tggtccacgc
    12601 ccagttgctt ggcggccggc tccaggatgg aggcccgcag gcgctgggcc tcctcctccc
    12661 ggccggccgc gcgcagcgtg atcgccaggt tggaacggca ggcgagcaca tcgggatgcg
    12721 tcggcccgaa ccgctccaac aggcccttga gcgcggtccg ttcccagcgc tctgccaggt
    12781 ccggccggcc gaggtcgccg taggcgttgg cgaggttgat cgccgcgcac agcgtgaacg
    12841 ggtgcctgga accgaggact tcctccaggg ccgcccgcac gtcctcgccg ccgcgcgccg
    12901 cctcctccgc ggcgccgaga ccccgctggt agatgtacag gttgttgcgg caggccaggg
    12961 tgaaggggtg ctcctcgccc agggtgctct ggtagccctc gtaggcctgg agggcgaggt
    13021 cgagggcggc ctgcttgtcg ccggtcgccg agaagtccgc ggccaggttc aggcagcagg
    13081 cgagcgcgtc cggcgccttg gtcccgtacc ggccgcggta gcggttgtac gtttcctcgg
    13141 tgagccgctt ggcctcgtgc gggtgcccgg ccttgcgcag ggacaccgcg aggctcttgg
    13201 cggtgcgcag cgcctcgggc acgtccgcgt tgaggacgcg ctcgaacgcc gccaccaccg
    13261 cgcgcagtac ctggatggag gcggcgtact cgccgctctc gcgcaggtcc cgcgccaggt
    13321 ggcccttggt ggtgagggtg aaggggtgct cctcgcccag cagggcgctg cgccgctcca
    13381 ccgtctcctc gtccagccga cgggccgcct cgctgtcgcc actgagccgg tagtcgatgg
    13441 cgaggttgtt ggccgcgatg agggtacggg gatggttctc gccgaagatc tggcgcagcc
    13501 cgtggtagat ccgcaggtcc cgggtgaggg cctcgtcgaa ccggccgagc gcgcgcaggt
    13561 cggcggcgag gctgccggtg gtgatgagga tgctggggtg gtcgtcgttg gggtggtcct
    13621 tgtgcaggac gctgatctgc cgggccaggg tgtcctcgtc catcgcccgg gcctcctggt
    13681 acttgccctg ggcgcgcagc gcgttggcca gctcgaagcg gatgttgagg gtctggaggt
    13741 cgttctcgcc gagctcgcgc gtccagacct tgttgagctg ggtgccgagc acccgggcgc
    13801 tctccagttc gccgcgcttg agcaggtagc ggatgcggtc gaccatcagc tggcggacct
    13861 tttcctcgtc gcagtccgcg atgccggagg cgctcaggtg cggccagatc agttcgaaac
    13921 tgggccagct cttggggtcg ttgaccgggt tgtcgcggtc gacgccctcc accgggcggg
    13981 cctcggcgag gatgcggtgc acctcgtgct tggcggtgtc cacctcttcc tcggtgagcc
    14041 cggcccgcac cgcggcctgg accagccggt gcacctggat gctgctgtcc gccgggtcga
    14101 ccttggcgag cgcgaaccgg ttcagcgtct ggatgacctt gcccagcatg taccgctcgc
    14161 gcagatccgg gtcgtacggc aggagtgact cgaacatcga gtcgctgccg atcagccgca
    14221 tcgagatggg ctcggccgag aagaacgagc acagctccaa caggcgtacc gccgccttgg
    14281 attcatcgcg cagccggctg atggagatgt tccaggtggc gccgatctgc tccgagtagt
    14341 cctcgggctt gccgagggag aggaccttgg tgctctgctc cctgagctgt tccacatacg
    14401 cgtcgaccgg cgtcgcggtc tcggcgagcc aggcggcggc gacctcgacc gcgaggggca
    14461 ggtcaccgac cgcgtcggcg acccggtcgg cgtcggcgac gggcagcttg gtgacccggc
    14521 ggcacaggtg ctcgatgctc tcggcgcggg tgaagacctc gacctcgatg ccctccacct
    14581 tcgtcgaggc gggtttgttg cggcaggtgg cgagtatgtg gccgtaggtc tcgcccgcga
    14641 tgggctccat ctcctccggg agcagtttca gcgcccggtc gaggtcctcg acattgtcga
    14701 agatcagcag ccagcgggag tacggagcgc cgcgccgcag cgcctggagg gcggccgcgg
    14761 cggcctcggc gaccacgtcg ccggccctca gatccatctc ggcggcgagt tcggcgagcg
    14821 aggacaccac ccggtcgggc tgctccgcct cgatccacca caccaggtcg tagtcggcgc
    14881 ggaagcggtg cgcgtactcc cgggccacct gtgtcttgcc gacgccgccg aggccgtaca
    14941 ggacctgggg gaagcgctgg gcggagcggc tgtcgccgcg cagttggtcg cgcagcttct
    15001 ccagcacggt ggtgcgtccg gtgaaccagg cgtgccgggg ccgtacgttc cagaccttgg
    15061 gcacgctgcc cgggtagcgc ggcccggccg gcgccgacgc gaaggccgcg accgcctcgg
    15121 accggtcgag cgcgttgagc acggccgccg ccgcgtcgtt ctcgtccagg cggaccaggt
    15181 cgatgacgcc ccggttgctg agcggcgggc tgagccgcac gtcgccgacc cgcacgggca
    15241 ggatgtggcg ccgcacgccc gccgcgtcga gcccgctccc ggtctcccag gagcttctgg
    15301 cccgctcgga gttgaggtag gcctgcgaga cgatcgggat gacgcggtag ccgattccgg
    15361 tggtgaactc gatctcgggc gtgccggttt ggggcgcgcg gacgtcgacc ggcacgacgt
    15421 ggaagccggc cacggtcagc acgtgcacca gccagtccac ccacatctgg tcctcggcga
    15481 catgggtgag gaccaggttc gacggcggca tgggccggcg ccgggtgtag gcggcgacat
    15541 gggtgagccg gtcggcctcg tccatgggcg gcagcgagtt gacgagtccg ccggtgagga
    15601 cggaggtgag gcgttcgcag gcgctgagca tggagctgct gacgttgggg gcgtcgccga
    15661 aggtggcgag gatctcctcg tacgcgtaga aggggcggta gggaacctcc accgtgcccc
    15721 agtagttgcc gagttcctcg gggctcaggc cgctggggaa cccggggaag ctctcccggg
    15781 ccagggcgcg tccggcgtcc gccttctcct tctcgccgtc gtcgatgcgc atcgggacgg
    15841 gcaggatgcg gatgcggcgc tcgtggtagc gctcctcgat gtcgcgggcc accgcggagg
    15901 cgccgtcgat gctctggtcg ctcaacgtga agcagacgac gaggacttcg ggcatctgga
    15961 cggtgcagat gtcggcgatg tcgctgagtc cggtgcggct gtcgatcagg gtgtagtcgt
    16021 agtggcgctg catgtcgtcg cgcatggcgt cgaagaactg gccaccgccg aaccgctcgt
    16081 ggaagtcgtc ccagtccatc ttgccgacga tggaggggta gtcgcggttg cgccgcccgg
    16141 ccgacaggaa gtccaggctg ccgccctggg ggaagttcca gttgagggag gtggcgtgcg
    16201 ggcgcacccg ggcgtattcg cggtgccagt cgggttcgcg gtcggcgggg cgccgggcct
    16261 cgtcctggta gtcggtgatc aggttgatca gacccggggt cgcctccagg tcggcgaggt
    16321 cgaggaaggg gtggaagaac cggtgcaggc ccggtgcctc caggtcccag tccactgcca
    16381 gtacccggta cccgttggcc gccaggatcc aggcgcagtt ggccagcgcc atggtccgtc
    16441 cggtgccgcc cttgtacgag tagaacgtga cgacggtccc gttgcggttc tcagtcatct
    16501 gatgagccct ccgccttatc accgtggttc ttgtcctggt ccgtgctctg accgcggccg
    16561 ctggggccac ccgcgccgta gccgatgccg ctgggcagga cccggggcat cggcccaccg
    16621 cttccgggcg gtgggtaggt cggcgcgttg gcctcgtagt gtttgaccgc cgccttcacg
    16681 gcccccggga tcgccttgct gaaggcttcc agtgtgggca gtccggcgct cggtgtgcgg
    16741 tgtccgtcgc tctcgtcgac ccgggcggcg agtgcggcgt cggtgtgctg cgacagctcc
    16801 tcgttgcgcg cgtgggtttc ggcgtcggcc acgttgccgg ggaccatgac gctgatccag
    16861 ggccgacggg tggcccccag ctggtcgagg agttcgcggc ggcgccgggc gtccagggcc
    16921 cagcggtcga gcagcagcag accgggcccg ggcgggcccg aggcgaggag ccgctgcggc
    16981 tcggcctcga agtcgctgag gtgcacggtg tagttcaggt tgcgtacgac gtcgacggtg
    17041 tggtcggcga gcggtctgga ggacgccggg tggtacgggt tccagtccag ggcctcggtt
    17101 ccgtagcagt ccgggctgcg tccggtgggg agactggagc gcgagcaggc gaggacggag
    17161 acctccattt cacgggccgg gccgccggtc gggccgaagg cgggcggcac cttggcgtag
    17221 tcctggtgcg ggtcgccgtg ctccagctgg gcctgctggg ccacgttcac gatgcgcttg
    17281 gccagccggt agacggcgcg ttcgtactgg tcgcgcaggt agttgagctt gatgagcccg
    17341 tagaagccct cgtcggcgta ctcgtcaccg aaggtggcgt ggttgaactg gagccgctcg
    17401 gcgggctgcg gcagctgccg cgtcggtacg ggcacccaca gcgcgggcac gatgccggtg
    17461 acggggttgc tgttgttgtt gctgtggcgg gtgttctgcg aggcggcccg gctggagaag
    17521 gcgaaccact cccggccgca ctgttcgctg aggaaatagc gcggtgaata gagcggtacg
    17581 aacaccttgc agtaggccag cgcctccgaa aggcgttcct gccagccctc accgggctgc
    17641 atctgctgat ccatgaagcc ggcgctgccg gccgggaggg gcgtcagctg catcacatgg
    17701 gcgcagaggt cccggaagaa ccgctggacc cacaggttgg ggtccttgtc cttggggtcg
    17761 ctcttcggcg tgtgcgcgta gctgaggaag aagtatggct tctgctcgtc tcccccggcc
    17821 cccactgatc cctgcaccac tgtctccccc ggtccaagtg gatgggacct cagtgtagga
    17881 acggaggatt ctccggcgga acagaacgaa caaacccatg aggagatcca ctcaccgagt
    17941 ttcgatcaga tcatgaccga aatcatgcgg agcccggtga gtggatcaat caatgggagg
    18001 gagaattcgc tcaattcgca ggtaaattca ctcggcgccg ccttcgacgc gggccttcca
    18061 ggcggcgcga tggcgccggg cggagtcctg cgccgcggtg agcgcggccg gagagacggc
    18121 ctcgccccgc caccccgaga cggtctcgcc catgcgtccg acgaaccgtt gccccaggtc
    18181 ggtgagggat gccgagccga gcagcacgtc gacggcctcc gccgtctgct gccgccagcg
    18241 cgcgaactcc gcctcggcca gagcccgttc gggtcccgtg cccgccgttt cacggcgcac
    18301 ccgccagaag tcggtcaccg cgatgtgggc gtacgttccc tggagcaagc caccgatcgg
    18361 gcgcggatcg gcgcgccagg gggcgtagta gcggtcgcgg tcggccttgt cgtagaggtc
    18421 gaccgcgtcg aggaccgcgg cgagcttcac gtgctggaac tcgtggacga tcagcagggc
    18481 gagctgttcg ggcgaggcgg gacgggccac cccgatcgca ccccaggcgt ccttgcaggc
    18541 ggcgctgacg tcgctgccgt ccggggcgtg cagaggtgtg atcagccgca gtcccgcggc
    18601 cacgccgtcg gcgtaggcgg gcagttcgcg ccggatcagg gaccaggcgc cggtcaggtc
    18661 ctcggaccac agcttggcct cgtcggccgc gagccgtgcc gcgacgggcc attcgtggca
    18721 gtcgcgcagc gggtcggtgt cctcgatggc cacgctccac ccctcgcccg cgaagaggcg
    18781 tacggggtgc cagtgcgggg tcaggccgtc catgccctcg tgccatccga tgtcgagccc
    18841 gcgcgcaccg gcccgcacgg tgaacccctc ggcgcccgcg gtcacttcgg cgtggccggc
    18901 cgagctgtcg agccgtacgg tgccgagtcc gggcagccgc agcatgccgt cgcgcagcgg
    18961 caccgtgacc gtgcggtcga ggcgggctcg cagcgtggtg gcggccgcga tctcggcgag
    19021 gcccgcggcg ggcgccaccc ggccttcgag cacgcccagc gcccacggtc gggtgtaggg
    19081 gtgcacgagg acaccggcga gttcgtcggg cacctccgcg tcgagctggg tcaacaggtc
    19141 ccaggcggcg gcgccttcgc ggtcggacag ggcgatgcgc tgctcgctga cggcggcgag
    19201 cagttcctgg ttgatgtcca gctgggctgc cgcgagacga gttacggtgt cggccccgcc
    19261 gaatccggtg gccagctcct cgaagtcggc ctgctccaga ggcagttcgg cggacgatgc
    19321 cttcggcgcg ggcacttccg cctcgcggtc gcggatggtg gtgaccaggg ccagcaggtc
    19381 ggggcagaac accgaggggt tgtcgaactc gctgccgtcg ctgcggtagc gatgggcgta
    19441 gaggccgccg ccgcaggact ggacgaccgg gcagtcgcgg cactgccggc agagctgctc
    19501 gatgccctgc tggcgggcga gcatgccggg gtgctggagt acgtcgtcga gcgagtgcgt
    19561 gaagacgtcc atgccggtgg ccggtgcccc gtcataggac gttttgagac tgtccgcctg
    19621 ctcgaaggtg ccgtcggtct cgatcacgac caggtcggcg ggggcgagcc ccagcgattc
    19681 ggtgaggctg ctctcgccgc gcagggtgcg cagcaccgag tcgaagatgc ggaccgggac
    19741 ggggcggccc gccgcgtccc agcggcggta gatcgcgtcg agccagtcgg cgtagggggt
    19801 ggccgcgccg ccggggcggg gcggcggcgt gtcccaagtg gcgtgcggca gaaggaagtc
    19861 gatgcgcggg ggcgacagct ccaccagggc gtcgtagacc gcgaccgggt cgttctcgac
    19921 gtcgatggtg cagagcagtc cggcgaacag gcgccggtag cgcgggcgtt ggaggagttc
    19981 gaccgcccgg atgaccttgg catggctgct gcgaccgtcc gcgtagcggc ggtggcggtc
    20041 gttggagacc ttgtcgccgt cgagggagac gccgaccttg atgccgagtt ccaggaagag
    20101 ttcgcagaac gcctcgtcga gcagcacgcc gttggtgtgc atgcgcagat ccagggcact
    20161 caccccgtgc agggcccgcc ggagttcctc ggcggcccgg cgcagtcggt cggggccggc
    20221 gagcagtggc tcgccgccgt gcagcacgac gtggacggtg gggagtcgat ggcgccgggc
    20281 gtgctcggcg atacggttcg ccacctgggc gaggatctcc tccgagacgg cgcggggcct
    20341 gccccgccag ctggtgtccg cgtgttcgta gacgtaacag tgatcgcacg ccaggtcgca
    20401 tcggctgtgc accttcagca cgaattgcga cagggcaggc ggaatcggcc ggtccatggg
    20461 gtgagtcgtt ccgcccgtca gagcgccgac tggaaggcgg acgcggcggg aaccgtgggg
    20521 ctcccgtacg ccgccatcac ccgggtgagg ttcgccggcg cacggccggc gccctgcgcc
    20581 gccgcccgcc gcaccagggg gagccacggg agggccggcc tgtggagggc ggggccgggc
    20641 cgtacggccg ccgagacgag agcgtccacg tgagcgcctt tcggatcgta gcgccgtgtc
    20701 tcgcagcggg gtctttccgg atcactgcgc aaacaggctc atggagaacg ttgcatgggc
    20761 ttttggtacg tcgtgcaatg cggccgcacg ccgtgcccat gtgcgctcat gcgccacgag
    20821 cgactggtcc gaccactgca gcctccccgg gacaccacaa ctgccttggc ccgtgcccag
    20881 gttcggcgtt gacgcggaat ccactcgcac gagtggtttc gtcccgggcg gactccgctt
    20941 ttcgtcgccc cccg
//
