LOCUS       NZ_CP070373            21059 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5184389
            Orig. end                         :: 5205448
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="26"
                     /rules="atropopeptide_p450"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            411..638
                     /locus_tag="GWQ54_RS22830"
     CDS             411..638
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059185.1"
                     /locus_tag="GWQ54_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5133 domain-containing protein"
                     /protein_id="WP_167160274.1"
                     /transl_table=11
                     /translation="MLMAHPVVLRDLLAEYEVLVALNAADGDEMTRQRLDDVTYTLCVS
                     TGTKDIDAAVVAARHRLPGARTFDDSVLTA"
     gene            728..1534
                     /locus_tag="GWQ54_RS22835"
     CDS             728..1534
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010269022.1"
                     /locus_tag="GWQ54_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_167161680.1"
                     /transl_table=11
                     /translation="MTDFDASERRIWAGRAEAYAESFGKLCAHPVPRLLDAARVRDGVR
                     VLDVGTGTGTAAAAACARGARVTGVDAEISMVDLAARSVPSAEMHLAELPRLPFSEGLF
                     DAVTANFVLNHVGRPKAALAELRRVVRPGGWVAVTIWAAPAAAGQTLLDRAVQAAGTSR
                     PPHLPGLAPEDDFARTVTGLTGLLASAGLKDATCEPLHWDHHTTAAAWWRGAADGIGTI
                     GQTVLSRPEHVRAEIERHFHRISAEFATPEGHLALPHAALLAHGRR"
     gene            complement(<1652..2680)
                     /locus_tag="GWQ54_RS22840"
                     /pseudo=""
     CDS             complement(<1652..2680)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375465.1"
                     /locus_tag="GWQ54_RS22840"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNGDSGSSLDFQKLFAARLQAARVRPYLASALFALHPVETRQVST
                     MAVDRHWRCYVSPAFVARMPVEELAGVWVHEVSHLLRDHHGRSDRFAREHQLTGRGERL
                     RMNIAADCEINDDVYGDGLVRPEGAVGPGCLGLPAGELTEDYLLKFAVGPSNWSTTWLD
                     CGSGADGLDREWEVGPGGAHGLSEQERDAVRFRVAEGIRGRPGSVPGGWRRWAEKAFHP
                     PLAWRELLGAAVRSAAGAGAGEDYTYGRPSRRSAAVPRIVLPSTVLPSLRRMPPRVCVV
                     IDTSASVSDAELGSALLEVAAIARAVGGRRDLVRVLPCDAAAPFVHSLFAPRGCPLIGG
                     GGT"
     gene            complement(2737..>3032)
                     /locus_tag="GWQ54_RS22845"
                     /pseudo=""
     CDS             complement(2737..>3032)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058186.1"
                     /locus_tag="GWQ54_RS22845"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="AAA family ATPase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SRDVLSMLVRGTVGDGPGLELLASLTSHAGTPPGPSWSRRSRRGR
                     RTWWSYRRAPSPHCAARTGTYPSRSSGSRARWRCPAGRVGRRPAREPGRRPSD"
     gene            3275..4822
                     /locus_tag="GWQ54_RS22850"
     CDS             3275..4822
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310580.1"
                     /locus_tag="GWQ54_RS22850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_167160272.1"
                     /transl_table=11
                     /translation="MTSSQPPPTIAATAPGSGGGGKGIALLVIAACQLMVVLDITIVNI
                     ALPHIQSALHFSTTGLAWVVSAYTLTFGGLLLLGGRTGDILGRRRVFMCGVLLFAVASL
                     LGGLSQSSGQLLAARAVQGVGGAIASPTALALITTTFTEGLERNRAFGVFAAVSAGGGA
                     IGLLAGGMLVEWLDWRWVLFVNVPIAVLILLATPRHIKESERHSGHFDIAGALASTGGM
                     VALVYGFIRAAQEGWRDPVTLGSFAVAVVLLCTFVMVERRSQQPITPLHMFADRNRAGT
                     YGIMLSLAAAIFGMFFFLTLFVQDVLGFTPLRAGLAFLPVSAIIAVGAGLASQLLPRYG
                     PKPFMVTGALLAAGGLSWLTQTDIHSTYLGSILGPILVFGLGMGLNFVSLTLMAVSGVP
                     PHEAGAASGMLNATQQVGGSLGLSILVTVFGTASRNEATDQVPKFLSQADAAQRLMFRR
                     TGQLPRPWSDQVLTSGVSTAFVVAAIFAVVAALIALIAIQVRPADLERLQGAKPTAP"
     gene            5063..6424
                     /locus_tag="GWQ54_RS22855"
     CDS             5063..6424
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="GWQ54_RS22855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_167160270.1"
                     /sec_met_domain="p450 (E-value: 3.3e-77, bitscore: 258.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATLPSRTGKAPGAWPLLGHAWQLHARPLEFLSSLPAHGDLVRI
                     GMGPWPAYVVCEPDAAHRMLTDSRTFDKGGPFFDKARVLFGSSLPMAGWQEHRWQRRQM
                     QPAFQSDRIEQYALVMGEEVDRMTGRWRAGQRLDVTAALTTLTLRIVTRSVLAAEAQDE
                     AVAEVQESLHTVIDGIYQRVMLPLGPLYRLPTPANRRYRHACDRLHRAIDGIIAARRAA
                     PGGNDLVSMLLTAVNDDTGEPMSDVDIRDQLMVMIGAGFETTANSLAFALWLLSQHPEA
                     EARVHDEVDRTLAGRTATTADLDGLTYTRRVVNEVLRMYPAGWFFTRVTTTDTTLAGRH
                     LPKGTALLYSAYLLHHRPELFPEPGRFDPDRWAAQAAESLPRGAHVPFGGGNRKCIGDQ
                     FALIEMTLALATVCTRWRLRPDPGSTMTVQVRGTLGPGPLPMTCEPRGRKSADT"
     gene            6611..7975
                     /locus_tag="GWQ54_RS22860"
     CDS             6611..7975
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090857.1"
                     /locus_tag="GWQ54_RS22860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_167161678.1"
                     /transl_table=11
                     /translation="MSVAALAQAPDRRRTEAWLLAFVVAITLGGHAATGLAMKGRLPAG
                     FGTFAGAVALFALVPHLVVRRWAARADPLLLPLALLLTGLGLVLLQRLDVTYLAEPRLH
                     MAPAGRGQLVWTAVGVASCGGLLIALRDHRRLQRYIYMMMAVALILLAAPAFFSADQFG
                     AKRWIMLGPLSVQPGEFVKIMIAVFFAGYLTVNRDALALSGRRFLGMRLPPGRQLGPIV
                     AIWVLSLLVLVFERDLGTSLIFFGLFVIMLYLATERTSWVVCGLLLAVVGAAVVGSLEP
                     HVHGRVEAWLHPMDAFTPAGQKARLSSQLGQALFSFGSGGMTGSGLGQGHPELVGFAGN
                     SDFILTTVGEELGLAGVMAVLLLYGLLAQRGLHIAMLARDPFGKLLATGLAGALVLQVF
                     VVTGGVTGLIPLTGKALPFLAKGGSSMVANWLMVGLLIRISDSARRRHEPDPHRL"
     gene            8101..8760
                     /locus_tag="GWQ54_RS22865"
     CDS             8101..8760
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059819.1"
                     /locus_tag="GWQ54_RS22865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167160268.1"
                     /transl_table=11
                     /translation="MVDPGSTPAPSQRRRKGGCLPALVVLLVILGLGFGASKLFGGGSD
                     KSGSSHSSSSASHDSGEWKVGDCGGPDPDDAPNGYKAFGCGDSGATFKALDIQAASFMP
                     DSIQCPAGTDLIIQVSISYGSTKSKGGGIPSKTVCGRNLSADHPGDPGAGGGQLVKGDC
                     VTDTAKEVSCASAGSGAYKVLGLTKETSQCPSGTTEPMRLTLAIGRPYDVICAAKQ"
     gene            complement(8785..10008)
                     /locus_tag="GWQ54_RS22870"
     CDS             complement(8785..10008)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="GWQ54_RS22870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_167160266.1"
                     /sec_met_domain="p450 (E-value: 3.6e-24, bitscore: 84.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETAASAEPGIQSLDPAFFDHPHATYREWRQEGAARRARYPGPA
                     PVEGWVVTSYADAKDLLADQRLSKGGAVERFGRHVGLTQGPGSALFSHMLNSDPPHHTR
                     LRKLVQKAFTTRRTAALRPAIEAHVAGLLDAWEGRDEVELIGEFALPLPLAVVFDLFGA
                     SDADHETLQVRGNTLDGGQGDGEVSVFTAESMLGYLRALLALKREQPDDGLLSALVEAR
                     AEGEEALSEDEITSMAFLLVIAGHQTTVNLIANGVHTLLTHPGQLALLRADMTLVPGAV
                     EEILRYESPSALASLRYAAEPVEVGEAVFGEGEFVQISLLGANRDPEVFADPDRFDINR
                     EDAARHLAFGYGIHHCLGAPLARLQAEIAFTQLLTRYPGLRLSEDHEARWQANPRHRGL
                     LSLPLRLT"
     gene            complement(10001..11059)
                     /locus_tag="GWQ54_RS22875"
     CDS             complement(10001..11059)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000172: Biaryl bond formation (68% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190930.1"
                     /locus_tag="GWQ54_RS22875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_167160264.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 7.4e-181,
                     bitscore: 599.5, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 1.4e-11, bitscore: 42.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTSRRTTVLAPRLQALLDEHLGKDLVRLEPDTIGIAGAELSDR
                     ILAARRATETERPTFKPLHGRSISKAEASSVMRTIGKDVRAALEQPDPLPASTDLSGPW
                     PITGHRFLSDLVLRDDPYRLRILMSRTLEIDPRLTWTTIVAGAALPRRPAPGPRLTHLA
                     NLFAEARTYDDRRYAMGIYRRAAAPVCFTVSTLVANALWLGSPFDDGASNRDILFEAMR
                     LLPPSWNLLRNRSPEYPAIDDRIGDGDDLLMLPLLTHRDPALWDAPNEFRPERWAGLDP
                     DNTPGYMPFGHVSERCWGRHMVMPLAELLLDHIRRTGLVVAPGQRTADVPLVGLLGVKT
                     VHIGHRSKVRHV"
     misc_feature    complement(11245..11259)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(11328..11339)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(11424..11435)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            11597..11848
                     /locus_tag="GWQ54_RS22880"
     CDS             11597..11848
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS22880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167160261.1"
                     /transl_table=11
                     /translation="MSCPVCSSRRYPCRGGLTPGSAPSPGCPLSGEERALRVQRRERFR
                     ELRSRPEWNQGRARGRRSRVGLLAWAVLALLLLALFLL"
     gene            12019..12408
                     /locus_tag="GWQ54_RS22885"
     CDS             12019..12408
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984768.1"
                     /locus_tag="GWQ54_RS22885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_167160259.1"
                     /transl_table=11
                     /translation="MTRNRADATVAQRFLTAFAAHDWEALHALFSVDLTWSMPGDGTIS
                     GTVYGADAAVDRARKIAGRGLATELRHILTGVHGVALSLHNTAEDADGRALDEHLATVL
                     TIRDGKVCAIDSYVSDVDGMSAFFS"
     gene            12458..12892
                     /locus_tag="GWQ54_RS22890"
     CDS             12458..12892
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS22890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167160257.1"
                     /transl_table=11
                     /translation="MNVSSEQHPHTARQLQAGQVVAIGWLLCGAALVERVPRFASGHRY
                     LLCHHSSALDRLTLTALALVLAAGVVALAGAIMMQAKNPHRVAFPVVCLVVVAALLVAA
                     DGVDAHGEKLATQLSATPFTAGACDYIPQDYVATPGWFFW"
     gene            complement(12986..13972)
                     /locus_tag="GWQ54_RS22895"
     CDS             complement(12986..13972)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141014.1"
                     /locus_tag="GWQ54_RS22895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="WP_167160255.1"
                     /transl_table=11
                     /translation="MRRVPVSTGVVAILVALLAAGFGAGTGHARDRFVRADDGARVVAE
                     QRIAPNRLDLTIDSPALGTTAQVRLLTPDGWSPGRHDWPSLWLLHGCCGGYTDWTTYSD
                     VAQLPSLRRVLVVMPEAGAAGWYSDWWNYGRGGAPRWETFHTAEVRQIVERGYGAGGRR
                     VAAGLSMGGFGALSYAVGHPGLFRAVASFSGTVHPLLQVPGGPGPDWFLNLDRTQGVDP
                     YAVWGDPVRQRTVWAAHDPTVRASALRGLPLFLSCGNGEAGPYDPAGAKDPNEAYFERQ
                     NRALADRLGALGSPVLTDFYGPGTHAWPYWERELHRSLPMLLAALAG"
     gene            complement(14173..15642)
                     /locus_tag="GWQ54_RS22900"
     CDS             complement(14173..15642)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (65-218). E-value:
                     6.4e-17. Score: 53.5. Matches aSDomain:
                     nrpspksdomains_GWQ54_RS22900_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209: polyketide synthase associated protein papA3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674246.1"
                     /locus_tag="GWQ54_RS22900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_167160253.1"
                     /sec_met_domain="Condensation (E-value: 1.4e-10, bitscore:
                     39.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITDLHGCEVRPGRLVEWSLDPAMVEAATSQPDDSRPPAYVQES
                     HIRTARSVRQDGLFVPTWLGAAFDILGPVDLDVLEAALRTWTLRHETLRSGFRWVDDEM
                     RRFTAAPDAVALRREVVGDFPDAEELSHHLQDRFDVEADALGWPNFLYTAVVRPESTSV
                     YMAFDHSNVDAYSIQRIPAEIHELYSARAEGRTEETAPVGSYVDFCEIERASADQVDDT
                     HAIVARWREFITRCDGRLPAFPVDLGLEPGGRLPEQKLLYKMLVDDADAAAFSAYCRPF
                     GGGQVGILAATSLIVHDIGGEPVYRTVVPLHTRAKSRWADSVGWYVGGAPIEIPVAQAR
                     GFDDALKMVHGALRANKALAHLPIARVLRLLGSDFRPTSPDLYSIVSFVDARDIPGARQ
                     WDELRASALLRVSYGDQVCAWFTRLHGGLQLAIRYPDTAIAHKNIHRYAEQLRELITSI
                     ARDAPAVPPRPRSERPVPAPRLSSEVSQLSL"
     aSDomain        complement(14989..15447)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GWQ54_RS22900_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.40E-17"
                     /label="GWQ54_RS22900_Condensation_LCL.1"
                     /locus_tag="GWQ54_RS22900"
                     /protein_end="218"
                     /protein_start="65"
                     /score="53.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DHSNVDA"
                     /tool="antismash"
                     /translation="AAFDILGPVDLDVLEAALRTWTLRHETLRSGFRWVDDEMRRFTAA
                     PDAVALRREVVGDFPDAEELSHHLQDRFDVEADALGWPNFLYTAVVRPESTSVYMAFDH
                     SNVDAYSIQRIPAEIHELYSARAEGRTEETAPVGSYVDFCEIERASADQ"
     CDS_motif       complement(15349..15450)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GWQ54_RS22900_0001"
                     /evalue="1.60E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="GWQ54_RS22900"
                     /protein_end="98"
                     /protein_start="64"
                     /score="26.9"
                     /tool="antismash"
                     /translation="GAAFDILGPVDLDVLEAALRTWTLRHETLRSGFR"
     gene            complement(16242..16637)
                     /locus_tag="GWQ54_RS22905"
     CDS             complement(16242..16637)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014909.4"
                     /locus_tag="GWQ54_RS22905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167160251.1"
                     /transl_table=11
                     /translation="MRRSTTVAAIALCGALAAGTAAPAYAAGQAPAVPVPGTGGESMGS
                     RAGDDDVAGVKAELAATMRDINQMIADEKKDAAADVAEAKAEVAAILKEISAMVKEELA
                     QAKPATKPSTAEPAPLSVPNTPPAATG"
     gene            16807..17355
                     /locus_tag="GWQ54_RS22910"
                     /pseudo=""
     CDS             16807..17355
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007826150.1"
                     /locus_tag="GWQ54_RS22910"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="NUDIX domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGERVERVDEQDRVLGVVERGEAVREGWLYRMAMVLCRDERGRCL
                     VHRRPEGVSRFPGEYSWLVAGAVGVGEPYADAARRELREELGVDAPVRPLFKFLCDGEL
                     GPYWFAVYETVVEEADVVADASEVA"
     gene            complement(17311..17598)
                     /locus_tag="GWQ54_RS22915"
     CDS             complement(17311..17598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060897.1"
                     /locus_tag="GWQ54_RS22915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_100573173.1"
                     /transl_table=11
                     /translation="MSRRYGGNPAATGILVIVDVMALILILWIAFFLVNANTANDIVSW
                     VRHAADWLSGWSRDMFTIRSDTWRTIVNYGLPAVVYLLIGHAVAGRVNRS"
     gene            complement(17707..18420)
                     /locus_tag="GWQ54_RS38130"
     CDS             complement(17707..18420)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS38130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_240361818.1"
                     /transl_table=11
                     /translation="MTKPERSASDQPLADKLVSGHDVPEQPGTHQPGIARDVPAGAAAD
                     QPLSGGAVPDRAAAGEPLTGRDVPERAVPDQSVAGRAVAPDQALPAQPGTGKHLTGQSA
                     AGQPVSERSLSGSGHPVAEQPAAEGRVPEQAGRRAAAESGAVDDGAVLPPHEREKLELR
                     LHHAVGGFVDEPRAAVEEAASAVDALTERIIETLGQRRGTLRASWQDASGGSATEDLRM
                     ALREYRRLAERLLSL"
     gene            complement(18417..19049)
                     /locus_tag="GWQ54_RS22925"
     CDS             complement(18417..19049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018530440.1"
                     /locus_tag="GWQ54_RS22925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167160249.1"
                     /transl_table=11
                     /translation="MSSGVVIILIAIVVIVVLAVVIGMFVARRGQGLRSRFGPEYERTV
                     AEHHGDVKAAEKDLDERVRRYGSLKVDPPSAEERSRYAAQWARVQEEFVESPTRAVAEA
                     EALLGRLANERGFPSGSSDEQLAALSVHHPQHLDSYRRIRGVAQGADGRRPSTEELRET
                     LVQAHEFFAVLAGERRGDKAGRLGVRGGRHASHSGTHYDDTARGSQS"
     gene            19260..19502
                     /locus_tag="GWQ54_RS22930"
     CDS             19260..19502
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532924.1"
                     /locus_tag="GWQ54_RS22930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chaplin"
                     /protein_id="WP_167160247.1"
                     /transl_table=11
                     /translation="MRIRTALAATVLAATAVIGTAGAAAADPNPPVVGSAHDSPGVLSG
                     DVIQVPVDIPVNACGDSIDLIGLLNPAAGNTCVNH"
     gene            19718..20017
                     /locus_tag="GWQ54_RS22935"
     CDS             19718..20017
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537948.1"
                     /locus_tag="GWQ54_RS22935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167160245.1"
                     /transl_table=11
                     /translation="MSTASHTEHAEHTHEHGTGCGHVAVPHADHVDYVHDGHLHRSHDG
                     HTDECEPGGHTVHEDHAHRHQAGCGHVSVPHGDHVDYVHDGHRHADHDGHWDDH"
     gene            complement(20083..20943)
                     /locus_tag="GWQ54_RS22940"
     CDS             complement(20083..20943)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.4"
                     /locus_tag="GWQ54_RS22940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cupin domain-containing protein"
                     /protein_id="WP_167160242.1"
                     /transl_table=11
                     /translation="MRWGVLDRLLGEPGSFFETCRLGRPRVFTPPFLPQEVPTLRELTG
                     ALGGGLMRTPYVELVRESEVVPAAELGAAAGTAHGAEEGFADPERIMHLLAEGATLLLP
                     RLGRWNASAGALTALLSQDLGRETEAFCFATTVGRRGRDVHCDDADVLVVQLAGRKEWT
                     VYEAPAHGDVRHGAVRTPAAPALCTVIGAGDVLYVPRGAPHRATGEDGLSAHLALTIRE
                     AARPAPDPTPGPITEAELLATARELLASARARVETRPHEEPLARTGGSPQSGARGIPAD
                     WPAAD"
ORIGIN
        1 gatcgccgcc acgagctcgt cgcggcgccc caggccgagc agcgccacgg cgaatccgtc
       61 ggtcccgtag aaggcatggc acagccccgc cgacaccagg gccgggcggg ctccccacgc
      121 ggccaagagg tcgctggtac gccccagatg cgccgccagc gtgccgcccg ggtgctcgat
      181 ctgcgcggcg ccggccgctt ccagcatgtc ccacgcctga gcattcacat gccggaacct
      241 gcccgccccg cgcgccggga aatcccgtgg gtacggcgga gcttgggacc cccgcccgtc
      301 aacaccgctc ggttcactca acaccgcctg gttcacgacg tgtagggcag gcgaagcggg
      361 gcacgggagc agcacatcgt gaacctctcg accaccgaag ggccccaccc atgctgatgg
      421 cgcatccggt agtgctccgt gacctgctcg ccgagtacga ggtcctcgtc gccctcaacg
      481 ccgccgacgg cgacgagatg acgcggcagc gcctggacga cgtgacgtac accctctgcg
      541 tctcgaccgg gaccaaggac atcgacgccg ccgtcgtcgc cgcacgccac cggctgcccg
      601 gagcccgcac cttcgacgac tcggtgctga cggcctgaac ggccgtccgc cccgggcatg
      661 ggccggctcc cgtagggtgc ccgaagtacc cgcgggggta cggcagggag aggcggtgcg
      721 ggtggtgctg acggacttcg acgcgagcga gcggcgcatc tgggcgggcc gggccgaggc
      781 gtacgcggag agcttcggca agctgtgcgc ccaccccgtc ccgcggctgc tcgacgcggc
      841 ccgggttcgc gacggcgtac gcgtgctgga cgtcggcacc ggaacgggca cggccgcggc
      901 ggcggcctgc gcgcggggcg cccgggtgac cggcgtggac gccgagatca gcatggtcga
      961 cctggccgcc cggagcgtcc cctcggccga gatgcatctg gccgaactgc cccgactccc
     1021 cttctccgag ggcctgttcg acgccgtgac cgcgaacttc gtcctcaatc acgtgggccg
     1081 ccccaaggcc gcgctcgccg agctgcgacg cgtggtccgg ccgggcggct gggtcgcggt
     1141 gaccatctgg gccgcccccg ccgcggccgg ccagaccctg ctcgaccggg ccgtccaggc
     1201 cgcgggcacc tctcgcccgc cgcacctgcc gggcctggcc cccgaggacg acttcgccag
     1261 gacggtgacg ggcctcaccg gtctcctcgc ctcggcgggc ctgaaggacg cgacctgcga
     1321 gccgctccac tgggaccacc acaccacggc cgccgcatgg tggcgcgggg cggccgacgg
     1381 catcggcacc atcggccaga ccgtcctgag ccggccggag cacgtgcgcg ccgagatcga
     1441 gcgccacttc caccgcatca gcgccgaatt cgccacgccc gagggccact tggcgctccc
     1501 gcatgccgcc ctgctggccc acggccgccg ctgacgcccc gcggtaccgg agccgggcgc
     1561 gccgcgcgag gggagtgcga gggccgtccg tctcggcacg gctccggtag gacgacgctt
     1621 cagcgcccgg acggccgcga ggaaccgatc ccgtgcctcc gccaccgatc agcggacatc
     1681 ccctcggggc gaacagcgag tgcacgaagg gggccgcggc gtcgcacggc agcacccgga
     1741 ccagatcacg tcggccgccc acggcgcgcg caatcgcggc aacctccagg agcgcactgc
     1801 ccagttcggc gtcgctgacc gacgccgacg tgtcgatgac cacgcacacc cggggcggca
     1861 tccgccggag gctcggcaat acagtgctcg gcagtacaat gcgcggcacc gcggccgaac
     1921 ggcgcgacgg ccggccgtag gtgtagtcct cccccgcgcc cgccccggcg gccgagcgca
     1981 cagccgcgcc aagcaactcc cgccacgcca gcggcggatg gaacgccttc tccgcccagc
     2041 gccgccaccc cccgggcacc gaaccggggc gcccgcggat gccctctgcc acccggaacc
     2101 ggaccgcgtc ccgttcctgc tcactgagac cgtgcgcacc accgggcccc acctcccact
     2161 cccgatcgag gccgtcggcc ccgctgccgc agtcgagcca ggtggtcgac cagttggacg
     2221 gcccgaccgc gaacttgagc agatagtcct ccgtgagctc accggcgggc agccccaagc
     2281 agcccggccc caccgctcct tcgggccgga cgaggccgtc tccgtacacg tcgtcgttga
     2341 tctcgcagtc cgcggcgatg ttcatccgca ggcgttcccc ccggcccgtg agctggtgct
     2401 cgcgcgcgaa ccggtcgctg cgcccgtggt ggtcccgcag caggtgcgac acctcgtgca
     2461 cccacacacc agcgagttcc tccaccggca tacgggccac gaacgctggg gacacatagc
     2521 accgccaatg gcggtcgacg gccatggtgg agacctgccg cgtctccacg gggtgcagcg
     2581 cgaagagggc cgacgccagg taaggacgga cccgagcggc ctgcagtcgg gcagcgaaca
     2641 gcttctggaa gtccagagag cttccggagt ctccgttcat cccaactggc ctgatccgca
     2701 cgcaatttga cggagcctca gccaggtcgc acgttctcat ctgacggcct tcgtccgggc
     2761 tcccgtgcgg gccgccgccc gacccgcccg gccggacagc gccaccgcgc ccgcgagccg
     2821 ctcgatcgac tcgggtacgt cccagtcctc gcggcgcagt gaggcgaggg tgctcgccgg
     2881 tacgaccacc aggtccggcg cccccgtctc gatcgccttg accaggaggg cccaggcggc
     2941 gtcccagcgt ggcttgtcag actggcgagg agttcgaggc ccggcccatc tcccacggtt
     3001 cccctgacca gcatcgacag tacgtcgcgt gagagggacg tcggcgtacg gctgccacca
     3061 cacccactac gcgggtgtac tgcgcaggcg tactcccaag gtgcactacg cgggtgtact
     3121 gcgcagatgt atttcgccca cacatacccc ggggccgtcg ccgcttgatc gactggtgac
     3181 gtgcggtacc ggggcatagg gtcgaacagt ggacagtgga cagtggacag tggacgtcac
     3241 cgtccatcgt ccctcgtgcg agggcaggtc catcatgacg agttcgcagc cgccacccac
     3301 gatcgcggcc acggcccccg gcagcggagg cggcggcaag gggatagcac tgctcgtcat
     3361 cgccgcctgc cagctcatgg tggtcctcga catcaccatc gtgaacatcg ccctcccgca
     3421 cattcagagc gcgctgcact tctccacgac ggggctcgcc tgggtggtca gcgcctacac
     3481 gctcacgttc ggcggcctcc tcctgctcgg cggccggacg ggcgacatcc tgggccggcg
     3541 ccgggttttc atgtgcggcg tgctgctgtt cgcggtcgcc tcgctgctcg gtggactgtc
     3601 ccagagttcc gggcagttgc tcgcggcgcg tgcggtccag ggggtcggcg gtgccatcgc
     3661 ctcgccaacc gctctcgcac tgatcaccac gacgttcacc gaggggctcg aacgcaaccg
     3721 ggcgttcggc gtcttcgccg cggtgtccgc gggcggcggc gcgattggtc tgctcgccgg
     3781 cggcatgctc gtcgaatggc tcgactggcg ctgggtcctc ttcgtgaacg tgccgatcgc
     3841 cgtgctgatc ctgctggcca ccccgcggca catcaaggag tcggagcgac attccggcca
     3901 cttcgacatc gccggagcgc tggcctccac cgggggcatg gtcgcgctgg tctacggttt
     3961 catccgggct gcccaggagg gctggcgcga cccggtcacc ctgggctcgt tcgccgtcgc
     4021 cgtggtgctc ctctgcacgt tcgtgatggt ggagcggcgt tcgcagcagc cgatcacgcc
     4081 gctgcacatg ttcgccgacc gcaaccgcgc gggcacgtac ggcatcatgc tgagcctggc
     4141 cgccgcgatc ttcggcatgt tcttcttcct caccctgttc gtgcaggacg tgctcgggtt
     4201 caccccgctg cgggccggcc tcgccttcct tccggtcagc gcgatcatcg cggtgggcgc
     4261 ggggctcgcc tcccaactcc tgcccagata cggccccaag ccgttcatgg tgacgggtgc
     4321 gctcctggcc gcgggcggcc tgtcgtggct cacgcagacc gacatccact ccacgtatct
     4381 gggcagcatc ctgggcccga tcctcgtgtt cggtctgggc atggggctga acttcgtctc
     4441 gctgacgctg atggccgtgt ccggtgttcc cccgcacgag gccggtgcgg cctccgggat
     4501 gctcaacgcg acccagcagg tgggcggttc actgggtctt tccatcctgg tgacggtgtt
     4561 cggcacggcc agtcggaacg aggcgaccga ccaggttccc aagttcctca gccaggccga
     4621 tgcggcgcag cgcctgatgt tccggcgtac gggccagctg ccccggccgt ggagcgatca
     4681 ggtgctgacg tccggagtgt ccacggcctt cgtggtcgcc gcgatcttcg ccgtggtggc
     4741 cgccctgatc gccctcatcg ccatccaggt ccgcccggcc gacctcgaac gcctccaggg
     4801 tgcgaagccc acagcgccgt gagacccggc ccggcatccg acggatgcct gttacgccaa
     4861 ctgcctgaca cagcaaggaa tatgacgggc catacgcaac cggcacctct atcacaggga
     4921 cttagcggag cgccagggag cgcggcgtag agccgggcgt gctgccgtgc gccgggttcg
     4981 gggcgcccgg gacggggaga gatattcggg atccggggcc gaggggcccc ggtcgccgga
     5041 ttcctgctgg aggtgcccca ccgtgagcgc gacgcttccc tctcgtacgg gaaaggcccc
     5101 gggtgcctgg ccgttgctgg gccacgcatg gcaactccac gcgcggccac tggagttcct
     5161 gtcctcgctc cccgcccacg gcgacctcgt gcgcatcggg atggggccct ggccggcgta
     5221 tgtggtctgc gaaccggacg cggcccaccg gatgctcacc gactcccgca ccttcgacaa
     5281 gggcggcccc ttcttcgaca aggcccgggt ccttttcggc agcagcctcc ccatggccgg
     5341 ctggcaggaa caccgctggc agcgccgcca gatgcagccg gccttccaga gcgaccggat
     5401 cgagcagtac gccctggtca tgggcgagga ggtggaccgg atgaccggcc gttggcgggc
     5461 cggccaacgc ctggacgtga ccgccgcgct gaccaccctg accctgcgca tcgtcacccg
     5521 cagtgtgctc gccgccgagg cgcaggacga ggccgtcgcc gaggtgcagg agagtctgca
     5581 caccgtgatc gacggcatct accagcgggt gatgctgccg ctcggcccgc tctaccggct
     5641 gcccaccccc gccaaccgtc gttaccgcca tgcctgtgac cggctgcacc gcgccatcga
     5701 cggcatcatc gcggcgcgcc gggcggcacc cggcgggaac gatctggtgt ccatgctgct
     5761 caccgcggtc aacgacgaca ccggcgagcc gatgtccgat gtggacatca gggaccagct
     5821 catggtcatg atcggcgcgg gcttcgagac caccgccaac agtctcgcgt tcgccctgtg
     5881 gctgctgagt cagcaccccg aggccgaggc ccgggtccac gacgaggtcg accggacgct
     5941 cgcgggccgc accgccacca cggccgacct cgacggtctg acgtacaccc gtcgagtcgt
     6001 caacgaggtt ctgcggatgt atccggcggg ctggttcttc acccgtgtca cgaccaccga
     6061 caccaccctc gcaggacggc acctgcccaa gggcaccgcg ctgctctaca gcgcctacct
     6121 cctccaccac cgcccggaac tgttccccga accgggccgc ttcgacccgg accgctgggc
     6181 cgcgcaggcg gcggagtccc tcccccgggg cgcgcacgtg ccgttcggcg gcggcaaccg
     6241 caagtgcatc ggcgaccagt tcgccctcat cgagatgacg ttggccctcg ccacggtctg
     6301 cacacgatgg cgtctgcgcc ccgatcccgg cagcaccatg accgtccagg tccgcggcac
     6361 cctcggcccc ggaccgctcc ccatgacctg cgagccgcgc ggcaggaagt ccgccgacac
     6421 ctgagccccg gcggaagcgg aacgggaacc accattgatc cactgccgtc tctcagcccg
     6481 tgatcgccgc gcgacgcggc ggcaggagat cccgggcctg cggctcgccg gggcggaggt
     6541 gctgcctgtg cggagtccga ccagcgggat ccgagtgcgg tccggggcgc ccggggacgc
     6601 ctggcgcacg atgtccgtcg ccgccctggc ccaggcaccg gacaggcggc gcaccgaggc
     6661 gtggctgctc gccttcgtgg tggcgatcac gctgggcggc cacgccgcga ccggactggc
     6721 gatgaagggc cgactgcccg cgggattcgg cacgttcgcc ggagccgtcg ccctgttcgc
     6781 gctggtcccg catctggtcg tacgacgctg ggcggcgcgc gccgatccgc tgctgctgcc
     6841 gctcgccctg ttgctcaccg gcctcggtct ggtacttctg cagcgcctgg acgtgacgta
     6901 cctcgccgaa ccacgtctgc acatggcccc ggcgggccgt gggcagttgg tgtggacggc
     6961 ggtcggggtg gcctcctgcg gcggcctgct gatcgcgctg cgcgatcacc gcaggcttca
     7021 gcggtacatc tacatgatga tggccgtcgc cctgatcctc ctggcggcgc ccgcgttctt
     7081 cagcgccgac cagttcggcg ccaagcgctg gatcatgctg ggaccgctgt ccgtacagcc
     7141 gggcgagttc gtaaagatca tgatcgcggt gttcttcgcg ggctacctca ccgtcaaccg
     7201 cgacgcgctg gccctgtcgg gccgccgctt cctcggcatg cgactgccgc ccggccgtca
     7261 gctcggcccg atcgtggcga tctgggtgct cagcctcctg gtgttggtct tcgagcgcga
     7321 cctcggcacc tccctgatct tcttcggcct cttcgtgatc atgctctatc tggccacgga
     7381 gcggacgagc tgggtggtgt gcgggctgtt gctggccgtg gtcggcgccg cggtggtcgg
     7441 ctccctcgaa ccgcatgtgc acggccgcgt ggaagcctgg ctgcacccga tggacgcctt
     7501 cactccggcg ggtcaaaagg cgcgcctgtc aagccagttg ggtcaggcgt tgttcagttt
     7561 cggcagcggc ggcatgaccg ggagcgggct cgggcagggc cacccggagc tcgtgggctt
     7621 cgccgggaac agcgacttca tcctcaccac cgtcggcgag gagctgggcc tggccggggt
     7681 gatggcggta ttgctcctgt acggcctgct cgcccagcgg ggtctgcaca tcgcgatgct
     7741 cgcccgcgat ccgttcggca aactgctcgc caccggcctg gccggcgctc tggtgctcca
     7801 ggtgttcgtg gtgaccggtg gtgtcaccgg tctgatcccg ctgaccggca aggccctgcc
     7861 cttcctcgcg aagggcggct cctccatggt cgccaactgg ctgatggtgg gcctcctgat
     7921 ccgcatcagc gactccgcgc ggcgccgtca cgagcccgac ccgcaccggc tctgaacgcc
     7981 cccggtgcgg gtcgggcagt cgcctcgcgc cgatcggaac catgaggtgt gcatgccgcg
     8041 tccacccctg tggtcaccac ccgtggccgc gctcaaccgc cgtccccagg gggaaacacc
     8101 atggtcgatc cgggtagcac gcccgcaccc agccaacgcc gcaggaaggg gggatgcctt
     8161 ccggcactcg tggttctcct ggtgatcctg ggcctcggct tcggggcgtc caaactcttc
     8221 ggaggcggga gcgacaagtc cgggtcgtcc cactcctcct cgtccgcctc gcacgacagc
     8281 ggtgagtgga aggtgggcga ctgcggcggc cccgaccccg atgacgcgcc gaacggttac
     8341 aaggcgttcg gctgcggcga ctcgggcgcc accttcaagg ctctcgacat ccaggccgcc
     8401 agtttcatgc cggactccat ccagtgcccc gccggtacgg acctcatcat ccaggtgagc
     8461 atcagctacg gcagcaccaa gagcaaaggc ggcggcatcc cctccaagac ggtgtgcgga
     8521 cgcaacctct cggccgacca cccgggtgac cccggcgccg gcggcggcca gttggtcaag
     8581 ggtgactgcg tcaccgacac cgcgaaggaa gtttcctgcg cctccgcggg ctcgggcgcc
     8641 tacaaggtgc tcggcctgac caaggagacc tcgcagtgcc cgtccgggac caccgagccc
     8701 atgcgtctga ccctggccat cggcaggccc tacgacgtga tctgcgccgc gaagcagtag
     8761 cgcgggcgtc cgggccgccc gcgtctacgt caggcgtagg ggcagcgaga gcaggccgcg
     8821 gtggcggggg ttggcctgcc accgcgcctc gtggtcctcg ctcagccgca ggccggggta
     8881 gcgggtcagc aactgggtga acgcgatctc ggcctgcagc cgggccagcg gcgcgcccag
     8941 acagtgatgg atgccatagc cgaaggcgag gtgcctggcg gcgtcctcgc ggttgatgtc
     9001 gaagcggtcg gggtccgcga acacctcggg gtcgcggttg gcgcccagca aggagatctg
     9061 cacgaactcg ccctccccga acaccgcttc gccgacctcg accggttcgg ccgcgtaccg
     9121 caacgaggcg agggccgagg gggattcgta gcgcaggatc tcctcgaccg ctcccggtac
     9181 gagcgtcatg tcggcccgca aaagggcgag ttgaccgggg tgggtcagca gggtgtggac
     9241 gccgttggcg atcaggttga ccgtggtctg atggcccgcg atcaccaaca ggaaggccat
     9301 cgaggtgatc tcgtcctcgc tgagcgcctc ctcaccctcc gcgcgggcct cgaccagcgc
     9361 ggaaagcagc ccgtcgtcgg gctgttcgcg cttgagggcg agcaacgccc ggaggtagcc
     9421 gagcatggac tcggcggtga acaccgacac ctcgccgtcg ccctgaccac cgtcgagggt
     9481 gttcccgcgc acctggaggg tctcgtggtc ggcgtccgag gcaccgaaga ggtcgaacac
     9541 gacggccagg ggcaggggca gcgcgaactc gccgatcagc tcgacctcgt cgcgcccttc
     9601 ccatgcgtcc aggagtcccg ccacatgggc ctcgatcgcg ggccgcaggg ccgcggtacg
     9661 gcgtgtggtg aacgccttct gcacgagctt gcgcagccgg gtgtggtgcg gtggatcgct
     9721 gttgagcatg tggctgaaca gagcgctgcc ggggccctgg gtgagcccga catgccgccc
     9781 gaacctctcc accgccccgc ccttggagag ccgttggtcg gccagcaggt ccttcgcgtc
     9841 ggcgtacgag gtgacgaccc atccctcgac cggggcgggc ccggggtagc gggcccggcg
     9901 cgccgcgccc tcctggcgcc actcgcggta ggtggcgtgg gggtggtcga agaacgccgg
     9961 gtcgagggac tggatgccgg gctcggcgga tgccgcggtc tcagacatga cgaaccttgc
    10021 tcctgtggcc gatgtggacg gtcttcacac cgagcagccc caccagtggg acatcggcgg
    10081 ttcgctggcc cggagccacc acaagtccgg tccgacgtat gtggtccagc aggagttcgg
    10141 cgagcggcat caccatgtga cggccccagc agcgctccga gacatgaccg aacggcatgt
    10201 agccgggggt gttgtcgggg tcgagtcctg cccagcgttc gggccggaac tcgttcggcg
    10261 cgtcccacag ggcggggtcg cgatgggtga ggagcggcag catcagcagg tcgtccccgt
    10321 ctccgatgcg gtcgtcgatg gccgggtatt ccggtgaccg gttccgcagc aggttccacg
    10381 acgggggcag cagccgcatc gcctcgaaga ggatgtcgcg gttggacgcg ccgtcgtcga
    10441 agggcgagcc gagccacagg gcgttggcaa cgagcgtgga gaccgtgaag cagaccgggg
    10501 cggccgcacg gcggtagatg cccatcgcat agcgccggtc gtcgtaggtc cgggcctcgg
    10561 cgaacaggtt ggccagatgg gtcagtcggg gcccgggggc gggccggcgg ggcagggcgg
    10621 cccccgccac gatggtggtc caggtgagtc tggggtcgat ctccagggtg cgggacatga
    10681 ggatgcgcaa ccggtacggg tcgtcgcgca ggacgaggtc gctcaggaac cggtgcccgg
    10741 tgatcggcca gggcccggac agatcggtcg atgcgggcag cgggtcgggt tgttcgagcg
    10801 cggcgcggac gtccttgccg atcgtgcgca tcaccgacga ggcctccgcc ttggagatcg
    10861 accggccgtg caggggcttg aaggtgggcc gctcggtctc cgtcgcccgt cgcgcggcca
    10921 ggatgcggtc ggagagttcc gcgcccgcga tgccgatggt gtcgggttcg agacggacga
    10981 ggtccttgcc gaggtgttcg tcgagcaggg cctgcaggcg aggggcgaga accgtggtgc
    11041 ggcgactggt acgggtcatg gcggatggca tacggagaac tccggaaatg aaaatgcgga
    11101 gggcccgcac acgcgactga ccgaaattca gtcggcctgc ctcgtgtgcg ggcccaggat
    11161 tggccttcgg cttagtacca gaagtaccag gcggcctgct tcaggctcgg ctcgctcttc
    11221 ttggcacgca gggcggcaat aatcttcgac atgattaatc ccttcctctc ggtgatatcc
    11281 ggatgtgaac caccggacgg atgcccttcc attcacacac ctggggcgtg ttcatttcca
    11341 gtcaccgacc gctgagggga agtgaagcgg gccacgacga gcgttgtcaa tggttccgct
    11401 tttcttcttt cctgtgagtc ctggcgttca agtacaaccg ctcgaaacat gcattgtggc
    11461 ggtacgaaaa gaagtgcccg aacggtcatg ggcgattgcc cggaaatacc tttcgacgct
    11521 catacccgcc tgctatcaag ggaaatgagt acgctgtggt tcccgccgtc ggctgtcgcg
    11581 cgagtgagga agtcccgtga gttgcccggt ctgctcgtcc cgccgctacc cctgccgggg
    11641 aggtctgact ccgggcagcg ccccgtcgcc cggctgtccg ctgagcggtg aggagcgggc
    11701 gctgcgcgtc cagcggcgcg aacggttccg cgaactcagg tcccggcccg agtggaacca
    11761 gggccgggcg cgtgggcggc gcagccgggt cggcctgctc gcctgggcgg tgctcgcgct
    11821 gttgctcctc gccctcttcc tgctctgacg cccgcgcctc ggcggtgccc ttgtggccac
    11881 gctccggcgg cggctccacc cgactccggg cgcggggccg ccggccgaac cccttattgt
    11941 cgggcgggcc acgggcgccc gtggcccgcc gggcgggcac cttcgcccgg cccgcccgac
    12001 ccaggagtgt gcgacgacat gacccgcaac cgagccgacg cgaccgtggc ccaacgattc
    12061 ctcaccgcgt tcgccgcaca cgactgggag gcgctgcacg cgctcttctc cgtcgacctg
    12121 acctggagca tgcccggcga cggcaccatc tcggggacgg tgtacggcgc ggacgcagcc
    12181 gtcgaccggg cgcggaagat cgccggccgg ggcctggcca ccgagttgcg ccacatcctg
    12241 accggcgtgc acggggtcgc cctctccctg cacaacaccg ccgaggacgc cgacggccgt
    12301 gcgctcgacg agcacctggc gaccgtgctg accattcgcg acggcaaggt ctgcgccatc
    12361 gacagctatg tgtccgacgt ggacggcatg agcgccttct tcagctagac catggccggt
    12421 gggcacacgc cggctcgacc gcacatccgg gggaaccgtg aacgtcagca gtgaacaaca
    12481 cccgcacacc gcacggcagt tgcaggccgg tcaggtggtc gcgatcggct ggctgctgtg
    12541 cggcgccgcg ctcgtcgaac gcgttccgcg cttcgcctca gggcatcggt acctgctgtg
    12601 ccaccactcg tcggccctcg accgactgac gctcacagcc ctcgctctgg tactggcggc
    12661 gggggtggtc gccctggccg gcgcgatcat gatgcaggcg aagaaccccc accgggtggc
    12721 cttccccgtg gtgtgcctcg tcgtcgtggc cgctctcctc gtcgcggcgg acggggtcga
    12781 cgcccatgga gagaagctgg cgacacagtt gtcggccaca ccgttcacgg cgggcgcgtg
    12841 tgactacatc ccgcaggact atgtcgccac accgggctgg ttcttctggt aggccacagc
    12901 cacatgggcc ggtgccctat ggacgggtgc cctatggacg gcgccacatg ggcggcgccg
    12961 cagtcgtccg gcgtccggtc gcgagtcacc cggccagcgc ggcaaggagc atcggcaggg
    13021 aacggtgcaa ctccctctcc cagtagggcc atgcgtgggt tccgggcccg tagaagtcgg
    13081 tgagcaccgg actgccgagg gcgcccaacc ggtcggcgag ggcccggttc tgccgctcga
    13141 agtaggcctc gttcgggtcc ttggccccgg ccggatcgta cgggcccgcc tcaccgttcc
    13201 cgcaggacag gaagaggggg agcccgcgca gtgcgctcgc ccgtaccgtg gggtcgtgcg
    13261 cggcccacac cgtacgttgg cgcacgggat caccccagac ggcgtacggg tccacgccct
    13321 gcgtgcggtc gaggttcagg aaccagtcgg ggccgggtcc gccgggcacc tggagcagcg
    13381 ggtgcacggt gccgctgaac gaggcgacgg cccgaaacag gcccgggtgg ccgaccgcgt
    13441 acgagagcgc gccgaaaccg cccatcgaga gaccggcggc gacgcgtcgg ccgcccgcgc
    13501 cgtagccgcg ctcgacgatc tgccggacct cggccgtgtg gaaggtctcc cagcgaggtg
    13561 cgccgcccct gccgtagttc caccagtcgc tgtaccagcc cgccgcgccg gcctccggca
    13621 tcaccaccaa cacccgccgc agggaaggga gttgggccac atcgctgtac gtcgtccagt
    13681 cggtgtaccc accgcagcag ccgtgcagca accacaggga cggccagtcg tgccgccccg
    13741 gcgaccagcc gtccggagtg agcaggcgta cctgggcggt ggtgcccagg gccggggaat
    13801 cgatggtgag gtcgaggcgg ttgggggcga tccgttgctc cgcgacgacc cgcgcgccgt
    13861 cgtcggcccg gacgaaccgg tcccgcgcgt ggcccgtgcc cgcgccgaaa ccggcggcca
    13921 gcagggcgac caggatcgcg acaacgcctg tgctgaccgg tacgcgacgc atcccgaccc
    13981 ccttgtgtga gccccgggcc cggtgcggaa caccgcgcca ctcggcgacc aatggccccg
    14041 ccggtctacc agccgcgtcc cttcgcgcgc gagaggcgct ccccggccac ccccatgtgg
    14101 cttcaccaca tgggggccgc acccatggcg tgtcctgccg ctggtggccg caccggctca
    14161 cccgtacggc tctcagagcg acagctggga cacctcgctg ctcagcctcg gcgccggaac
    14221 cggtcgttcc gagcgcggcc tcggcggcac ggccggagcg tcccgggcga tcgaggtgat
    14281 gagctcgcgc agctgctccg cgtagcggtg gatgttcttg tgcgcgatcg ccgtgtccgg
    14341 gtagcggatg gccagttgca gcccgccgtg cagccgggtg aaccacgcgc acacctggtc
    14401 gccgtaggag acccggagca gcgcggacgc ccggagctcg tcccactgcc gggccccggg
    14461 gatgtcccgg gcgtccacga acgacacgat cgagtagagg tcgggggacg tcgggcggaa
    14521 gtccgagccg aggagccgca gcacccgtgc gatcggcagg tgggcgagcg ccttgttggc
    14581 ccgcagcgcg ccgtggacca tcttcagggc gtcgtcgaac ccccgcgcct gtgccaccgg
    14641 gatctcgatg ggcgccccgc cgacgtacca ccccaccgaa tccgcccacc gggacttcgc
    14701 tcgggtgtgc agcggcacca ccgtgcggta gaccggctcg ccaccgatgt cgtggacgat
    14761 gaggctggtc gccgccagaa tgccgacctg cccgccgccg aacggccggc agtacgccga
    14821 gaaggcggcg gcgtccgcgt cgtccacgag catcttgtac aggagcttct gctcgggcag
    14881 tctcccgccg ggttcgagcc cgaggtccac cgggaaggcc ggcagcctgc cgtcgcaccg
    14941 ggtgatgaac tcccgccagc gcgccacgat cgcgtgggtg tcgtcgacct ggtccgcgct
    15001 ggcccgctcg atctcgcaga agtcgacata gctgccgacc ggtgccgtct cctcggtgcg
    15061 cccttcggcc cgcgccgagt acagctcatg gatctcggcg gggatgcgct ggatcgagta
    15121 cgcgtcgacg ttgctgtggt cgaaggccat gtagacgctg gtggattcgg gcctgacgac
    15181 cgccgtgtac aggaagttcg gccagcccag ggcgtccgcc tccacatcga aacgatcctg
    15241 gaggtggtgg ctcagctcct ccgcgtcggg gaagtcaccg acgacctcac gccggagcgc
    15301 caccgcgtcg ggcgcggcgg tgaagcggcg catctcgtcg tcgacccagc ggaagccgct
    15361 gcgcagcgtc tcgtgccgca gggtccaggt ccgcagggcc gcttccagga cgtccaggtc
    15421 gaccggcccc aggatgtcga aggcggcgcc cagccaggtc ggcacgaaca ggccgtcctg
    15481 gcgcacggac cgagcggtcc tgatgtgtga ttcctgcaca taggcggggg gccgggagtc
    15541 gtcgggctgg ctggtcgcgg cctcgaccat ggcgggatcc agactccact ccaccagccg
    15601 tccgggacgg acctcgcagc cgtgaaggtc ggtgattcgc acgggagttg tccattcaca
    15661 agctgtcggg gaacacgggc gagcggcggg ccgcgggtgc tggtacggct gcgcgggaac
    15721 gcccgccgcg gccggccctg cggagcacct ggcggcagtc ggccggacag ggcgagcggc
    15781 ccggccgggc gcgtacggcc cgatggcccc ggacacggcg cgcggcgcgg cagacgaccg
    15841 ctgccccggt ccggccctcg caccccgagt gctcccctgc ggggcaggcc gggccggccg
    15901 gatcgcacgg ctgccccggc cccggtgcca caacgcccct cagcggggca cccgttggag
    15961 agggcgtcgg gcgagtcgcg gccgccgcgc accgcagccc aagaaatacg gtcatgtggt
    16021 gaccaacgcg ggacaggcgc tcccgggcac gcagaaccac cccatcgagt cgtttgcgcc
    16081 gaccggcgcg tcctcacgcc cccgaaggga tcgcactccc gccccgcggc ccatgaggct
    16141 ttgcccagcc cccaactccc cctgtgacac gccgatttgt agctcgcgcg acccggatgg
    16201 ggcaggcagc ggggcgcggc gggaagcagt cgggccgcgc gtcagcccgt cgcggcgggc
    16261 ggcgtgttcg gcaccgacag cggggcgggc tcggccgtgg acggcttggt cgccggcttc
    16321 gcctgcgcga gctcctcctt gaccatggcg gagatctcct tcaggatcgc cgccacctcc
    16381 gccttggcct cggcgacgtc cgccgcggcg tccttcttct catcggcgat catctggttg
    16441 atgtccctca tcgtcgccgc cagctcggcc ttgacgccgg cgacgtcgtc gtcaccggcc
    16501 cggctgccca tcgactcgcc tcccgtcccg gggacgggta cggccggcgc ctgtccggcg
    16561 gcgtaggcag gtgctgcggt acctgcggcg agggcgccgc acagggcgat cgcggcgacg
    16621 gtggtactac ggcgcatgat cgcgctcctc atcaggtcga cggcatccag gtcactccac
    16681 tctcgatcca ctgttcgcca ccatcggatg gagggccacc cgggccttcc gaacgagtga
    16741 gcccggtctg acgctccgtc ggggggtgcc gcacatggcg cggcggccgt catggaggat
    16801 cgggccatgg gtgaacgtgt ggaacgggtc gacgagcagg atcgtgtcct cggcgtcgtc
    16861 gagcggggcg aggccgtgcg cgagggctgg ctgtaccgga tggccatggt gctgtgccgt
    16921 gatgagcggg gccgctgcct ggtgcaccgg cgcccggagg gcgtctcacg ctttccgggc
    16981 gagtacagct ggctggtggc gggggcggtg ggtgtgggcg agccctacgc ggacgccgca
    17041 cgccgggagc tccgcgagga gctcggggtg gacgctccgg tgcgtccgct cttcaagttc
    17101 ctgtgcgacg gggagctcgg accgtactgg ttcgcggtgt acgagaccgt cgtggaggag
    17161 gcggacgtcg tggcggacgc gtcggaggtc gcctgacacg gctggctgac cgacgacgag
    17221 ttgagggcgg ccatggcgag ctggaagttc gtctcggaca gccgggacgc ctatacccgc
    17281 tatctcgccc tcggctcgtc cggccaggac tcaggagcgg ttgacccggc cggccaccgc
    17341 gtggccgatg agtaggtaaa ccacggcggg cagaccgtag ttgacgatcg tgcgccaggt
    17401 gtcggacctg atggtgaaca tgtcgcgcga ccagcccgag agccagtccg ccgcgtggcg
    17461 cacccacgac acgatgtcgt tggccgtgtt ggcgttcacc aggaagaagg cgatccagag
    17521 gatcaggatc agggccatga cgtcgacgat gacgagtatg ccggtggcgg cggggttacc
    17581 gccgtagcgc ctggacatgt ccaactcctt gtctgtaccg atgggttgag gtgccgagcc
    17641 ggtcgaccgt gacgtgcccc gggggcgcca cgggggcgcc cgccgggaca cgggggatgt
    17701 cggtcctcac aggctgagca ggcgttccgc gagcctgcgg tattcgcgca gggccatccg
    17761 gaggtcctcg gtggccgaac cgccggacgc gtcctgccag gacgcgcgca gcgtgccgcg
    17821 ccgctgtccg agggtctcga tgatccgctc ggtcagggcg tcgaccgcgg aggccgcttc
    17881 ctcgaccgcc gcgcggggtt cgtccacgaa cccgccgacc gcgtggtgca gcctgagctc
    17941 cagcttctcc cgctcgtggg gcggcagtac ggcaccgtcg tcgacagcgc cggactcggc
    18001 cgcggcccgc cgcccggcct gctcggggac gcgcccctcg gccgcgggct gttccgccac
    18061 gggatgcccg gacccggaca gggaccgttc ggacacgggc tgcccggctg cggactgtcc
    18121 ggtgaggtgc ttcccggtcc cgggctgggc gggaagggcc tggtcggggg cgacggcgcg
    18181 cccggccacg gactggtcgg ggacggcccg ttcggggacg tcacggccgg tcaacggctc
    18241 tccggcggcg gcccggtcgg ggacggcacc cccactcagg ggctgatcgg cggcggcccc
    18301 ggcgggaaca tcgcgtgcga tgccgggctg atgggtgccc ggctgctcgg ggacgtcgtg
    18361 ccccgagacg agtttgtcgg ccaggggctg atcggatgcg gaacgctcgg gcttggtcat
    18421 gactggctcc ctcgggcggt gtcgtcgtag tgcgtgccgc tgtgggacgc gtgccggccg
    18481 ccgcgcactc cgaggcgccc ggccttgtcg ccgcggcgtt ccccggccag tacggcgaag
    18541 aactcgtggg cctgtacgag ggtctcgcgc agttcttccg tgctgggcct gcgcccgtcg
    18601 gcgccttggg cgacgccacg gatgcggcgg tagctgtcca ggtgctgggg gtggtgcacc
    18661 gaaagcgcgg ccagttgttc gtcggacgag ccgctcggga agccgcgttc gttcgcgagc
    18721 cggccgagca gcgcctcggc ctcggccacc gcgcgggtgg gcgattccac gaactcctcc
    18781 tgaacacggg cccattgggc ggcgtaccgg ctgcgctcct cggcgctcgg ggggtcgacc
    18841 ttcaggctgc cgtaccggcg gacccgctcg tcgaggtcct tctccgcggc cttcacatcg
    18901 ccgtggtgct cggccacggt ccgctcgtac tcgggtccga accggctgcg caggccttgg
    18961 ccccgccgcg ctacgaacat gccgatgacc accgccagaa caacgatcac cacgatcgct
    19021 atcaggatga tgacgacacc actggacatg gcctgccttc ccgttggaga acggccccgc
    19081 actacgggct gtcctccacc gtgtagacgc gaaacggccg aataaacgcg ccgtcaaggg
    19141 acgtgtcccg cgacttccgc gcgacggacc gttcacccca tcgggtcacg cgattttccc
    19201 ccgcgccgga acacggagac gctgcagagg aacaacccac cacaaactgg aggaaaatcg
    19261 tgcgtatccg taccgcactc gccgcaactg tcctggccgc cactgccgtc atcggcacgg
    19321 cgggtgccgc agcagccgac cccaacccgc cggtcgtcgg ctcggcccac gactccccgg
    19381 gcgtgctgtc cggcgatgtg atccaggtcc cggtcgacat cccggtcaac gcgtgcggcg
    19441 acagcatcga cctcatcggg ctgctcaacc cggcggccgg caacacctgc gtgaaccact
    19501 gacgcaccgc ccgcgcaccc gacttcgccc cggaacggca ccagggttcc ggggcgaagc
    19561 cgcgttcccc gcaccggcac cgctcggcca aggaccgggc cgctgcggaa acagcccggt
    19621 tcacctcgcg tcggacgtgc attgccgccg cgcccggagc agactcgccc tcgcgagggg
    19681 ggccggcgaa gaacagaacg aacaggaaag caacgtcatg tcgactgcca gccacaccga
    19741 gcacgccgag cacacccacg aacacggcac cggctgcggc catgtggccg tgccccacgc
    19801 agatcacgtg gactatgtgc acgacggcca tctccatcgg tcccacgacg gccacaccga
    19861 cgagtgcgag ccgggcggcc acaccgtgca cgaggaccac gcccatcgcc accaggcggg
    19921 ctgtggacac gtttccgtac cgcacggcga ccatgtcgac tacgtccacg acggccaccg
    19981 tcacgccgac cacgacggcc actgggacga ccactgagcg tcggccgccc ctgaacacgg
    20041 ccgcatcgac tccggcgcga tccccgctcg gtccgcggcc ggtcagtccg cggccggcca
    20101 gtcggccgga atccccctcg cccccgactg cggcgatccg cccgtccggg cgaggggctc
    20161 ctcatggggg cgcgtctcca ctctcgcccg cgcactcgcc agcaactccc ttgctgtggc
    20221 gaggagttcg gcttcggtaa tcggtcccgg cgtgggatcc ggcgccggtc ttgccgcctc
    20281 gcggatggtg agggcgaggt gggcggagag gccgtcctcg ccggtggcgc ggtgcggggc
    20341 gccgcgcggt acgtacagga cgtcacccgc accgatgacg gtgcacaggg cgggcgcagc
    20401 cggagtccgg accgcgccat gacgtacatc gccgtgggcc ggggcctcgt acaccgtcca
    20461 ctccttgcgg ccggcgagct gtacgacgag gacatcggcg tcgtcgcagt gcacatcgcg
    20521 gccccggcgc cccaccgtcg tcgcgaagca gaacgcctcc gtctcgcggc ccaggtcctg
    20581 ggagaggagg gccgtcaggg cgccggccga ggcgttccac cggccgagtc ggggcagcag
    20641 gagcgtggcc ccctccgcga gcagatgcat gatccgttcc ggatcggcga agccttcctc
    20701 ggccccgtgg gccgtgccgg cggcggcacc gagctccgcc gccggtacga cctcgctctc
    20761 ccgcaccagc tcgacgtacg gcgtgcgcat cagaccgccg ccgagcgctc ccgtcaactc
    20821 ccgtagtgtg ggcacctctt gaggcaggaa tggaggcgtg aacacacgcg gccggcccag
    20881 gcggcacgtc tcgaagaacg acccgggctc gcccagcagg cggtcaagca ctccccaacg
    20941 catcgtctct ccccaggtcg ggggcggtcc ggcgccgccc tcagccgaac ctacgggagc
    21001 gatcacgcat atgccccggg acgatcgggc agcgtaggcg gtcgcgaagt cgcgggatc
//
