LOCUS       NZ_CP070373            21107 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4993473
            Orig. end                         :: 5014580
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="24"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11107)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    220..234
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     misc_feature    complement(725..739)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(1497..2309)
                     /locus_tag="GWQ54_RS21985"
     CDS             complement(1497..2309)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662769.1"
                     /locus_tag="GWQ54_RS21985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_167161725.1"
                     /transl_table=11
                     /translation="MMSSNEANWDARTPVHLASRFYGVADKSADPERWFADYEWRDLGD
                     LAGLDVLHLQCHLGTETMAFANRGARTVGLDLSGASVSAARTLAAEAGLDVAYVRGNVY
                     DAARLLPDRQFDVVYTGKGALCYLPDLPRWAETVASLLRPGGRLYLAEFHPLLNSLGPS
                     PAPGAGPELLLRNDYLGGKGPVRRDATYTYTDGPAVQGATECYEWMHGLDEIVDAVLGA
                     DLRLVRLRESDELPWPRWPQMVRTPQGWWRLPDSEPRIPLLFTLTAQR"
     gene            complement(2443..3084)
                     /locus_tag="GWQ54_RS21990"
     CDS             complement(2443..3084)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1226: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020554281.1"
                     /locus_tag="GWQ54_RS21990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="WP_205380443.1"
                     /transl_table=11
                     /translation="MVDVPAGRVTLSDRRTQRSWQVDLRPYRLAEFPVTQAGYAEVTGG
                     RPSTARGARLPVEGVSWLDAVRYCNALSLREGLTPAYREVEGEGVEWDDASDGYRLPSE
                     GEWEHACRAGTTQARYGPLDEIAWHRGNSDERPHEVGGRRPNAWGLHDMLGNVWEWCWD
                     VYDAEVYGSYRVLRGGGWFDEPWSCRASVRRRSHPTFRIDDVGFRVARSG"
     misc_feature    complement(3103..3117)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(3142..4398)
                     /locus_tag="GWQ54_RS21995"
     CDS             complement(3142..4398)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957107.1"
                     /locus_tag="GWQ54_RS21995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_167160526.1"
                     /transl_table=11
                     /translation="MTAASATETVEAVFRIESARIIAGVARIVRDVGIAEELAQDALVA
                     ALEQWPASGVPDNPGAWLMATAKHRAIDLVRRKETYARKLAEVGRALEDTAPPDPAESD
                     DPDRIDDDLLRLIFTACHPVLSTQARIALTLRLLGGLTTQEIARAFLAPEPTVAQRIVR
                     AKRSLAKAGVPFEVPYGADRNARVGSVLEVIYLVFNEGYSATAGDDLVRPALCEDALRL
                     VRVLGALMPKEPEVHGLAALLEFQASRIAARTGPGGEPVLLADQNRAKWNRLLIRRGVE
                     ALQRAGDGPYSVQAAIAACHAHAIRYEDTDWASIAVLYGRLLTMTPSPVIELNRAVAVA
                     MSEGPEAGLRLVDALGDEPALKDYHLLPSVRGDLLERLGRRAEAGAEFERAASLTRNAQ
                     ERELLLNRAEVNGRPQQGI"
     gene            4515..4994
                     /locus_tag="GWQ54_RS22000"
     CDS             4515..4994
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158040.1"
                     /locus_tag="GWQ54_RS22000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_167160524.1"
                     /transl_table=11
                     /translation="MAQLQLLRLDHGPALLDFERENRRYFAATIPDRGDDYFAEFDARH
                     AALLAEQEAGTCRFHLVVGDDGAVLGRVNLLDLDGGSAELGYRIAERATGQGLATASVR
                     DVCALARAAYGLTSLTARSTLDNPGSRAVLTRNGFTPTADIELNGRPGLRFVRVL"
     gene            5171..5572
                     /locus_tag="GWQ54_RS22005"
     CDS             5171..5572
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133907.1"
                     /locus_tag="GWQ54_RS22005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_167160522.1"
                     /transl_table=11
                     /translation="MRIGELSERTDTSRRLLRYYEEQGLIISTRSANGYRNYDENLVDR
                     VLQIRGLLDAGLPTRIIRQILPCLNKPRAIHFPDATPEMLATLTLERDRMTQRIECLIR
                     NRDAVSEYLDTVSGKRREEPSSAATAATH"
     misc_feature    complement(5736..5750)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.41"
                     /tool="antismash"
     gene            5839..>6096
                     /locus_tag="GWQ54_RS22010"
                     /pseudo=""
     CDS             5839..>6096
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949731.1"
                     /locus_tag="GWQ54_RS22010"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="esterase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGLTSNKVLALTVLCAVVMFAVTIWMWPRLSRHTWKTVLGRLGLL
                     IATQFLVFAAVGLATNNSFLFFGSWTDLFGQEQGVGVVVNH"
     gene            complement(6196..7116)
                     /locus_tag="GWQ54_RS22015"
     CDS             complement(6196..7116)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947935.1"
                     /locus_tag="GWQ54_RS22015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_167160520.1"
                     /transl_table=11
                     /translation="MSQTTSAPVASPAGFSDVKGWFWPADQLLFDWFLKRQDRVPEQNG
                     DLLELGAYLGKSAIFIGGYLRPGEKFTVCDLFDSPAPDDPNSAEMGRSYSTLTRRGFEA
                     NYLAFHEQLPTVVQAPTSVIGSRLDAGSCRFIHIDASHLYEHVHGDIVAARELAAPDAI
                     VAFDDFRAEHCPGVAAAVWGAVATMELKLICITGTKAYGTWGDPEPARAELLDWLAPRT
                     DLWHGVEEVAGAPLIRIDGKKAKAPTPPQPLRPVSETPKTAESPRTPEAAGEPGTSGPS
                     TPGPAASVPAAAPRGLLARALGRRR"
     misc_feature    complement(7110..7120)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            7499..7861
                     /locus_tag="GWQ54_RS22020"
     CDS             7499..7861
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883979.1"
                     /locus_tag="GWQ54_RS22020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SPW repeat protein"
                     /protein_id="WP_229860934.1"
                     /transl_table=11
                     /translation="METRGVAAVEELVILAGIYAAISGWTVHFSAAKPTLALSNLVVGI
                     ALAVLGLCMSMAPERSTDLNFVVLLLGAWLIVSPWVVARSAGTGAILSNVITGACVCLF
                     SLVAGGMLMSRNRRST"
     gene            complement(7973..8536)
                     /locus_tag="GWQ54_RS22025"
     CDS             complement(7973..8536)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358465.1"
                     /locus_tag="GWQ54_RS22025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_167160518.1"
                     /transl_table=11
                     /translation="MNLFEAQAIATARLDLVPLRVDHAEEMAGVLSDPALHAFIGGVPD
                     TPEALRTRYERLAGGCPDPGASWLNWVVRLRDEGRLTGTVQATVTPGGPGDTAEIAWVV
                     GTAWQGRGIATEAARGLVAWLDRQSVRTVLAHIHPEHRASEAVAAAAGLAVTDAWQDGE
                     RRWLRRSAAHGDDARANSGSQSGR"
     misc_feature    complement(8686..8701)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            8913..9968
                     /locus_tag="GWQ54_RS22030"
     CDS             8913..9968
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743438.1"
                     /locus_tag="GWQ54_RS22030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isopenicillin N synthase family oxygenase"
                     /protein_id="WP_167160516.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 9.7e-22, bitscore:
                     76.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASMSYVTSSQLPIIDLSAADRGPEARRQLHAQLHSAAHGVGFFQ
                     LVGHGVTDAETAALNDTMRTFFRLPEADRLAIDNVNSPHFRGYTRIGDERTGGSRDWRD
                     QLDIGAERPARVPGPGEPAYWWLEGPNQWPAALPELRTAALNWIDRLSAVAEKLLHELL
                     ASIGAPQDFYDDAFGDRAHLHLKLVRYPGSAEDGTAQGVGAHKDYGFLTLLHQDTVGGL
                     QVQREDGRFHDVPPLPGAFVVNLGELLEVATNGYLLATNHRVVSPPGATERFSVPFFYN
                     PRLDAHIEPLTFPYAAHAPGATADPANPLFAEYGRNELKGKLRAHPLVAARHHAGLLLT
                     ERPLAGSALPV"
     gene            complement(10001..11107)
                     /locus_tag="GWQ54_RS22035"
     CDS             complement(10001..11107)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998436.1"
                     /locus_tag="GWQ54_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_167160515.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.6e-56, bitscore:
                     188.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPQAGLHTPDSLRSPRTTAASSTTTTPRAVAALARCRELVEPAL
                     RKAVQGLHPEPGRIAAHAFGWCDADGTPGVGSGGKGVRPALAVLGTQAVGASADAAVPA
                     AVAIELIHTFSLMHDDIMDGDERRRGRDSSWKAFGSGPAVLAGDALFALAVRTVAEADD
                     ACGARAVRQLAVMLGELVHGQADDVLFETRPWTGPHAVGLAEYRAMAARKTGSLLGCAT
                     ALGPVLAGAPPRLADALAQAGREWGLAFQAVDDVLGIWGDPEVTGKPVHSDLRRGKKTL
                     PVLAAMAAQPSLGPRLEGLLGGGTPPDEASVRCAADLVEEAGGRAYALRDARTRVAAAR
                     DRLRAAPLVTRRVDDLVALSELLLDRRV"
     gene            complement(11167..12213)
                     /locus_tag="GWQ54_RS22040"
     CDS             complement(11167..12213)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906849.1"
                     /locus_tag="GWQ54_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_167161721.1"
                     /transl_table=11
                     /translation="MYGKASAPEYRGPLGELSVNTSLEEVLAKAVEEMRLAEQGGKSLE
                     LAHAALAAAEASRRLGRVEEAEQAWQDSFRAAERAGDRGAMAWAVWSGGTLARQRGDLA
                     LARRRLAEAAELAEQGGDIVARGYSLAGLAETGRIQGDYEAVGRLHEQLLAEARRRGEA
                     RHTVWALEGIAQMHRNTGSFDTALAMFEEAARIARDAGDDRGRAWALRGMADVRSAQGE
                     PERALALLTEAELLCREVQLVGALAYNHKMRGNVLYRAGRYAQAEEVYRGALAEFRAMG
                     EPRGEALSRLGLVKAEARQGRPAASTAADLDALERALGDIGLQRAGDMIAQARTELGVP
                     ASDAVPTP"
     gene            complement(12358..13599)
                     /locus_tag="GWQ54_RS22045"
     CDS             complement(12358..13599)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980116.1"
                     /locus_tag="GWQ54_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="styrene monooxygenase/indole monooxygenase family
                     protein"
                     /protein_id="WP_167160513.1"
                     /transl_table=11
                     /translation="MRRIAIIGAGQAGLQLALGLQGADYDVTLHSERTSQEIRAGRVTS
                     TQLMFGPALALERAAGLNLWDDRAPVMRGLEMRHWDPAEDGRPTRFTASYDGEVRSVDQ
                     RLKLAAWLDLFESRGGRVAYGSVEAGDAPAVVACHDLTVVAAGRGALSSLFGRDAACSV
                     YDRPQRTLAAFYADGVAGRGDETDAYLRVSGAAAAGDAIALQALTEHGPCEILLVEAKF
                     GGPYDCWADRPEPREGLRRAVELLRQYAPWEYERFARAEPTDDGAALYGAITPTVRHGV
                     ASLGDGQYVLGMADAVAVNDPLTGQGANNAARAAAAYLDAILKREEQPFDERWMRTVFD
                     DYWEQARHVHAFTDLMLRQPPAGHVVRILQAAHEHPEVAHRLANGYADPVGYRDWLMEP
                     ERAEAYLARFDGSR"
     gene            complement(13680..14552)
                     /locus_tag="GWQ54_RS22050"
     CDS             complement(13680..14552)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014625.4"
                     /locus_tag="GWQ54_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_167160511.1"
                     /sec_met_domain="PIG-L (E-value: 1.7e-15, bitscore: 56.6,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLAWGQIVVPVDSAAAAAPPCRSTVLAGVAHEDDDLLFMSPDL
                     VADRDKGACLDIVYLTAGDAGSPGTRYVQQREQGVGQAYALLAGAPNEWRREDRRHAGR
                     TVRAFVLRVPAGRPGVRVTFLRLPDGIHDGSGTRAQAGQSLLKLERGSIRRMTAMDRSA
                     SYDKKELTTMLAWLVADAHARTVRTLDYRNTDYGTGPKGDHSDHEVAARFVRAAAATVP
                     GSKPVVVGYRGYSIRALRPNVAVQPARRKESAFRRYLTTTECPKGCTDYKGPLSALYRN
                     WMLRQYPTA"
     misc_feature    complement(14717..14732)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            14718..15641
                     /locus_tag="GWQ54_RS22055"
     CDS             14718..15641
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642111.1"
                     /locus_tag="GWQ54_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="WP_167160509.1"
                     /transl_table=11
                     /translation="MTLLTAAVVQAGSPLFDTPAALAKALDLIRAAAARGAQVVVLPEA
                     FLGGYPKGFDFGVRVGSRSPEGRDTFRRYFESAIAVPGAETDELAALTVELSIHAVVGA
                     VERSGSTLYCVALFFGPQGYLGKHRKLMPTAAERLIWGLGDGSTMPVVDSGRGLLGAAI
                     CWENYMPLFRTTMYAKGVDIWCAPTVDDRETWQVTMRHVALEGRCFVLSAAQYLLRSDL
                     PPDVHPVQGDAPDTVLIGGGSTIVSPLGEVLAGPLRDGEGILVADLDLGDIARSRFDFD
                     PTGHYARPDLFTLHVDETPRPPTRAG"
     gene            complement(15802..16794)
                     /locus_tag="GWQ54_RS22060"
     CDS             complement(15802..16794)
                     /NRPS_PKS="Domain: PKS_ER (17-183). E-value: 7e-25. Score:
                     79.7. Matches aSDomain:
                     nrpspksdomains_GWQ54_RS22060_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669090.1"
                     /locus_tag="GWQ54_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_167160506.1"
                     /sec_met_domain="ADH_N (E-value: 2e-18, bitscore: 65.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-22, bitscore:
                     77.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIRFAGAGRPLNLEIVPDPEPGPEWVVVDIEAAGLCHSDLHIM
                     SGMDLGDLTVKSPVTLGHEGAGVISSVGDGVRDFEVGDRVGIALVSHPIEEALFAPGVG
                     HDGAFAEQELAHVSTLVHIPDNVTFAEAAVATDSVATAYHAVRTAGAVRPGRTVGVIGL
                     GGLGLNGVRIAKLLGATVYGVDVNPSTFGPATEAGATACFQDVRQLTAQQPDVIVDFAG
                     VPSTAAAAVECVRPGGCVVLVGLGGAVAPIPIASLVMRNVQLVGSLGASKEELREVYGL
                     IASGALKPAVQEVPFSELPAAMDRLARGEVRGRLYTRPRADLRVPVEIA"
     aSDomain        complement(16246..16743)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GWQ54_RS22060_PKS_ER.1"
                     /evalue="7.00E-25"
                     /label="GWQ54_RS22060_PKS_ER.1"
                     /locus_tag="GWQ54_RS22060"
                     /protein_end="183"
                     /protein_start="17"
                     /score="79.7"
                     /tool="antismash"
                     /translation="VPDPEPGPEWVVVDIEAAGLCHSDLHIMSGMDLGDLTVKSPVTLG
                     HEGAGVISSVGDGVRDFEVGDRVGIALVSHPIEEALFAPGVGHDGAFAEQELAHVSTLV
                     HIPDNVTFAEAAVATDSVATAYHAVRTAGAVRPGRTVGVIGLGGLGLNGVRIAKLLGAT
                     VYG"
     CDS_motif       complement(16576..16614)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GWQ54_RS22060_0001"
                     /evalue="7.90E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="GWQ54_RS22060"
                     /protein_end="73"
                     /protein_start="60"
                     /score="9.4"
                     /tool="antismash"
                     /translation="LGHEGAGVISSVG"
     gene            complement(16977..20159)
                     /locus_tag="GWQ54_RS22065"
     CDS             complement(16977..20159)
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01180.1"
                     /locus_tag="GWQ54_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="WP_205380421.1"
                     /transl_table=11
                     /translation="MLRSVPSSGPAVRPRRPSRGVSAFSALALSALGLVGLAAAVPAHA
                     AALPLTQYVDPFIGTDDSNAPNPVPGGAGGSTYPGAVVPFGGVQAGPDTPTASPSGYRY
                     KDTSVEDFSLTHFDGAGCPNNEDLPLLPVTGALGSSPGTNWTSYASGYTKANEVAKPGY
                     YKTRLDRYATDVELSATTRTAMGKLTYPASTASRLLINTGRSATGNRAGSVHINGNELT
                     GSVTAGGFCGSSKTYQIYFDVRFDRTPTGFGTWSGGSVSDGSATASGTNTGAYVTFDTS
                     TNATVQFKVGLSYVSIAGAQANVAAENAGWDFGAIRTAADTSWNQMLNRLQVTGGSATE
                     RQKFYTALYHVLQSPNISSDVNGDYRGFDNAVHNASRPVYQNYSGWDIYRSWASLIALM
                     APTEASDIAKSMVLDGQQGGLLPKWSQQTNEDFVMTGDPGPIIVSSLYAFGARDFDTSA
                     ALSLMEKASNGGTAQGGAIRGRQSTYTSLHYLDDPSDSLEYSASDFAVAQFAKALGNTS
                     SYNTHMGRAQWWRNTFNSESSYVQQHQSDGSWSWPLDPASQSTFTEGNASQYTWMVPYD
                     FSDLINSMGGAGTAVQRLDHHFTEVNAGQSRPYYYIGNEPEHGVPWAYNYARHPAGATD
                     AVRKVMDESFTTGAGGLPGNDDLGATSAWYVWAALGMYPATPGADTLAVHGPQFPSILI
                     QRAAGNITINSSGSGPYVQALAVNGTSTSHSYLRYPDVAGGATLNYTMGAAPSGTWGTG
                     ASDVPPSFQDGATPVPAAPELGTDLALGKPVTGSASCAAAESADKAVDGSLTNNSKWCS
                     SAANPSLQVDLGSVRNVSSFVIKHAGLGGENTGWNTGAFQIQTSTDGTAWTAAASVTGS
                     RSSRTYHPVSARSARYVRLVVTSPSNTSGGGSDAARIYELEVYGPSGGSRDLAIGQPAT
                     GSASCNATETPEKAVNGSFTGGTGDKWCSKVSGTKTLQVDLGASHPLSSITVRHAGAGG
                     ESADWNTKDYDLSVSGDGATWTTAAQVRGNTADSTTSTVTGSARYVRLGVLVPAQNTDP
                     AARIYELEVNGS"
ORIGIN
        1 gagcacgatc gcgttgacgc cctgcgcctt gagctgggcc gcacagcggt tcgcggtctc
       61 cagctcctcg gtcatgcgca gtgcggtctg gaaactcgtg gaaccggtgt cggtgccggt
      121 gaccgtcaga tgaatgaatc cgatcggcag gcgcttgccg ttcggcccct gcacccattc
      181 gacattcacc ggcggaagga cggtcttccc cgtattcccc cacagcatgt tggccgagta
      241 gtaacggaag ttcgcgccgg gaaaggtccg tccggtggag tccgggaaac tgttcgtcca
      301 gcccgccccg gcgtacggtc tgccgtgttc catgtggttg atcaggaatc cgggagtgcg
      361 gtcgaactcg tggtttccgg cggtcgagaa gtcgagctgc atccggttga gcgcctcgat
      421 ggtgggctcg tcggccagcg actcggccgg gaacgcccag cccgagaaca ggtcgccctg
      481 tccgaagaac agcgtgttgg tgcggccggc ccgcaggttc ttgaggtgcg tggccatgta
      541 gggcacgccg ccgacggtga actgttcgcc gcccgcgccc gtgatgaccg cgtcgctcgc
      601 gggcggggcc gccaggtatc cgtgcaggtc ggtgatgctg agcagctgta cgtccacgta
      661 ctcggtggcg gtctcggcgt cacgcgcgtg tccgctggcc agcgccgagg tgcccgtcgc
      721 cgccatcgtc gcgagtgatc ccgccacggt catgaagctc cgtcgaccca cgccccacat
      781 ttcgactccc tcattcgaaa gctatgcggc catgccggga gcggtgttcc ggctccccac
      841 ctggcggccc gaagaactgc gtgacacgaa tccgccgatt gcgggcacaa ggaatacaac
      901 acggcaggat ggccgaaccc tcgacacgcc gccggaccaa gggcgccgaa atccgggtcg
      961 ccaacatgtc ccactcaagc gcacgaacca cacgacgagc gaaagatgcg cgaaactcgg
     1021 tggtggtgtc acatgacgag ttgctgaact gaatcgggcg tccttcaacc cggcccgcgc
     1081 acgagtgtca tgaatggacg tcaggaaccg gaggaatgcg gtgccggtgc tgagtgcccg
     1141 ttcggggcgg agttcgccga caccgcggga taatcggctc cgccctctcc tcatcgcaga
     1201 ccgcccttcc ccggtgcccg ccgcacccca caggagggcg gcactccgca ccgggtttcc
     1261 gcgcgcccgg cacggttcaa ccgttcccat cacggcggtc ggtgtacgtc tggagcgctg
     1321 ggggccaggg gccgcctact ggccgtctcg cgccgcgccg gcacaggggc cgggcgccca
     1381 cggagatgca cttgttggca gtgtcccccg ccgccgatgc tccaaatcgg tctgcgggca
     1441 agggagttga aggatcaaga cactgggaca ccgggaggct ccggcgtcgg gtggcttcag
     1501 cgttgcgcgg tcagggtgaa gagcagcggg atgcggggct cgctgtcggg cagccgccac
     1561 cagccctgcg gggtccggac catctgcggc cagcgcggcc agggcagctc gtcgctctcc
     1621 cgcagccgga cgagccgcag gtccgcgccg agcacggcgt cgacgatctc gtccagaccg
     1681 tgcatccact cgtagcactc ggtcgcgccc tgcacggcag gaccgtccgt gtaggtgtac
     1741 gtggcgtcac ggcgcacggg ccccttgccg cccaaatagt cgttgcgcag cagcagctcg
     1801 ggcccggcgc cgggggcggg cgagggcccg agggagttca gcagggggtg gaactcggcg
     1861 aggtagagcc gcccgccggg acgaaggagg gaggcgaccg tctcggccca ccggggcagg
     1921 tccgggaggt agcagagcgc gcccttgccc gtgtagacga cgtcgaactg ccggtccggc
     1981 aggagccggg ccgcgtcgta gacgttgccc cgcacgtatg ccacgtcgag gcccgcctcg
     2041 gcggccagtg tgcgggcggc ggacaccgaa gcaccggaga ggtcgaggcc cacggtgcgg
     2101 gctccacggt tggcgaacgc catcgtctcg gtgccgagat ggcattggag atggaggacg
     2161 tcgaggcccg ccaggtctcc gaggtcgcgc cactcgtagt cggcgaacca ccgctcgggg
     2221 tcggcgctct tgtcggcgac accgtagaaa cggctggcga ggtggaccgg ggtacgggcg
     2281 tcccagttcg cttcgttgga cgacatcatc cgctgcacag ccgggtcgaa gtcttcggtc
     2341 gtgtcggtca accggtcccc ctcaaggcgc cacgtcggca ccgaccctac ccaggtcgtg
     2401 cgtcggccgg taccgctgcg ccgcaccccg tcggcatgtc gttcagccgg agcgcgcgac
     2461 ccggaacccc acgtcgtcga tgcggaaggt cggatggctg cggcgtcgca ccgaggcccg
     2521 gcagctccag ggctcgtcga accagccccc gccccgcagc acccggtagc tgccgtagac
     2581 ctcggcgtcg tagacgtccc agcaccactc ccagacgttg cccagcatgt cgtgcagccc
     2641 ccacgcgttg ggacgtctgc cgcccacctc gtgcggtcgc tcgtccgagt tgccgcggtg
     2701 ccaggcgatc tcgtcgaggg gtccgtagcg cgcctgcgtc gtcccggccc ggcacgcgtg
     2761 ctcccactcg ccctcgctcg gcagccggta accgtcactc gcgtcgtccc actcgacgcc
     2821 ctcgccctcg acttcacgat aggcgggggt cagcccctcc cgcagcgaga gggcgttgca
     2881 gtaacggacg gcgtccagcc aggagacgcc ttccacgggc agccgcgcgc cccgcgcggt
     2941 actcggccga ccgccggtga cctccgcgta gcccgcctgg gtcaccggga actccgcgag
     3001 ccggtacggc cggaggtcca cctgccaact gcgttgcgta cgccggtccg acagcgtcac
     3061 ccgccccgcg gggacgtcga ccatcgtgtc tctcactgcc ccatccacga ccatgatcgg
     3121 ccgatcctaa caacggcgcc ctcaaatccc ctgctgtgga cgcccgttga cctcggcacg
     3181 gttcaggagg agctccctct cttgggcgtt gcgggtcagc gaggccgcgc gctcgaactc
     3241 cgccccggct tccgcccgtc ggccgaggcg ttcgaggagg tcacctcgta cgctcggcaa
     3301 caagtggtag tccttcaggg ccggttcgtc cccgagggcg tcgaccagac ggagcccggc
     3361 ctcgggtccc tcggacatag cgacggcgac cgcccggttc agctcgatca ctggggacgg
     3421 ggtcatcgtc aggaggcggc cgtacaggac ggcgatcgac gcccagtcgg tgtcctcgta
     3481 gcggatggcg tgtgcgtggc aggcggcgat ggccgcctgc acggagtagg ggccgtcccc
     3541 ggcgcgctgg agggcctcga cgccccgccg gatgagcagg cggttccact tggcgcggtt
     3601 ctggtcggcg agcagtaccg gttcgccgcc gggcccggtc cgggccgcga tgcgtgaggc
     3661 ctggaactcc aacaaggctg ccaggccgtg gacttccggc tccttgggca tgagtgcgcc
     3721 cagcacccgc accaggcgca gcgcgtcctc gcagagcgcc gggcgcacca ggtcgtcgcc
     3781 ggccgtcgcg gagtacccct cgttgaagac gaggtagatg acttcgagga ccgagcccac
     3841 ccgggcgttg cggtccgccc cgtacggcac ctcgaatggg acgccggcct tggcgagcga
     3901 gcgtttggca cggacgatgc gctgggcgac ggtgggctcc ggggccagga aggcgcgggc
     3961 gatctcctgc gtggtcaggc cgccgagcag ccgcagcgtg agcgcgatcc tggcctgggt
     4021 ggacagcacg ggatggcagg cggtgaagat gagccgcagc aggtcgtcgt cgatgcggtc
     4081 cgggtcgtcg gactcggccg gatcgggcgg cgcggtgtcc tccagcgccc gcccgacctc
     4141 cgccagcttg cgggcgtacg tctccttgcg gcgcaccagg tcgatggcgc ggtgcttggc
     4201 ggtggccatg agccaggcgc ccggattgtc ggggacgccg gaggcgggcc actgctccag
     4261 tgcggccacc aacgcgtcct gcgcgagctc ctccgcgata cccacgtccc gcacgatgcg
     4321 ggccaccccc gcgatgatcc gcgcggactc gatcctgaat accgcctcga ccgtctcggt
     4381 cgcactcgct gccgtcacgg gcacccatca gagcagcacc gcgggggtgc ggcaagccga
     4441 cgcggcgccc ccggtccacg actgggcccc gccccccgca acagcggccg cacccgggtg
     4501 cgtagccttg cggcatggcc cagctccagc tcctccggct cgatcacggt cccgctctgc
     4561 tggacttcga gcgggagaac cgccgttact tcgccgcgac gatccccgac cgcggcgacg
     4621 actacttcgc cgagttcgac gcccgccacg cggcgctgct ggccgagcag gaggcgggaa
     4681 cgtgccgctt ccacttggtg gtgggcgacg acggcgcggt gctcgggcgc gtcaacctgc
     4741 ttgacctgga cggtggttcg gccgagctcg ggtaccgaat cgccgagcgg gccacgggac
     4801 aggggctcgc cacggcatcc gtccgcgacg tctgtgccct ggcccgcgcg gcgtacgggc
     4861 tgacgtcact gacggccagg tcgaccctgg acaatcccgg ttcccgggcc gtcctgaccc
     4921 gtaacgggtt cactcccacc gcggacatcg agctgaacgg ccgccccggc ctccgcttcg
     4981 tacgggtcct gtgaccacgc gacctccgct gcgcatgggg ccggtgacca ccggcccgcg
     5041 ctacgtatgg ggcctgtggc cacccggccc gcgggccacc gcccggccgg gcgctgccct
     5101 acactcgcct ccaccttgac accggtgtga ggctcgggcc tcgatccagt acgtccgcga
     5161 ggaggggcac atgcgcatcg gcgagctctc ggagcgcacc gacacatcgc gtcggctgct
     5221 gcgctactac gaggagcaag gcctgatcat ctccacccgc tccgccaacg ggtaccggaa
     5281 ctacgacgag aatctggtgg accgggtcct gcagatccgc gggctgctcg acgcgggcct
     5341 gccgacacgc atcatcaggc agatcctgcc ctgcctcaac aagccacggg cgatccactt
     5401 cccggacgcc acaccggaga tgctcgccac gctcaccctc gaacgcgacc gcatgacgca
     5461 gcgcatcgag tgcctgatcc gcaaccgcga cgcggtgtcg gagtatctcg acacggtgag
     5521 cggcaagcgg cgcgaggagc cgtcatcggc ggccaccgcc gccacgcact gacacgccaa
     5581 cagtcccggc tgatccgcgt accgggcgac aacgcgtggg ctccacgatc agcagagtgc
     5641 cgtcgctacc gaagacccga aggtgtgctc ggcccacatg actggccggc ccaacggcaa
     5701 aggatggcga tgccccgtac tcgaagggat ctcgctggaa cggatcgtgc tccatccctg
     5761 tctactcttc tgagcacccc cgagcggtgc cactcgggcg cgcccggggg aacgtctggc
     5821 agagagttct atcgacccat gggtctcacg agtaacaagg tgctggcact gaccgtgctc
     5881 tgcgcggtgg tcatgttcgc cgtcaccatc tggatgtggc cgcggctgtc acgtcacacc
     5941 tggaagacgg tcctcggccg gctcgggctg ctgatcgcga cgcagttcct ggtgttcgcc
     6001 gccgtggggc tcgcgacgaa caactccttc ctgttcttcg gctcctggac ggatctcttc
     6061 gggcaggaac aaggcgtcgg cgtggtggtc aaccactagg ttccgcaagc cagttgccac
     6121 ggccccggcc cccgccgcgg ggcggctcgt acgagcgggc cgcccggagc acaggggacc
     6181 ggggccgtgc cctgctcagc gacggcggcc gagggcccgg gcgagcaggc cccggggcgc
     6241 ggccgcgggg acggaggcag caggcccggg cgtcgaagga ccggaggttc ccggctcccc
     6301 cgccgcctcc ggtgtccgcg gtgactccgc tgtcttcggc gtctcggata cgggtcgcag
     6361 cggctggggc ggggtgggcg ctttggcctt cttgccgtcg atccggatca gcggcgcgcc
     6421 ggccacctcc tccactccgt gccacaggtc cgtgcgcggg gccagccagt cgaggagttc
     6481 cgcccgcgcc ggctcgggat cgccccaagt cccgtacgcc ttcgtgccgg tgatgcagat
     6541 gagcttcagc tccatcgtcg cgaccgcgcc ccacaccgcc gccgcgaccc cgggacagtg
     6601 ttccgcccgg aagtcgtcga acgccacgat cgcgtcgggg gcggcgagtt ccctggcggc
     6661 cacgatgtcg ccgtggacgt gctcgtacag atgcgaggcg tcgatgtgaa tgaagcgaca
     6721 gctgcccgca tcgaggcggg agccgatgac ggaggtggga gcctggacaa cggtgggcaa
     6781 ctgctcatgg aatgccaggt agttcgcctc gaagccgcgg cgggtcaggg tcgagtacga
     6841 ccttcccatt tcggcactgt tggggtcgtc gggagcaggc gagtcgaaga ggtcgcagac
     6901 cgtgaacttc tcgccgggtc ggagatatcc gccgatgaaa atcgcgctct ttcccagata
     6961 ggcaccgagt tcgagcagat caccgttctg ttcggggacc cggtcctggc gcttcaggaa
     7021 ccagtcgaac aggagttgat ccgccggcca gaaccagcct ttgacgtcgg agaagccggc
     7081 cggggacgcc accggtgcac tcgtcgtttg tgacatggcc cggtcctact cctgccagat
     7141 ggccggaagg tggccggggg gcatggcccc ggcgcctccg gctgaaactc cccgtacagc
     7201 ccgggaaaac cggcactcgc cagcggattc gccgcccgga ggccgcactt cgaccacaat
     7261 ccgtagcggc cttgatgcgc agggtgtcat ttcgcgggac atcgagatcg accattcccc
     7321 cgactacaca taaaggggat gtaagcgcac aatggggatc gcgacatagt gtcgcagcgc
     7381 ggccagacgt gcagatcttc agaaggaggc gagtcggatg gccgacgtct cacaccgccc
     7441 cggtgatata tccgggcacc ccgatgtatc ggagatgcgg gaccgctacg ccaaggtgat
     7501 ggaaacccga ggagtagcag cggtcgagga actcgtgatc ctcgccggca tttacgcagc
     7561 gatctccggc tggacggtcc acttctcggc cgccaagccc accttggccc tcagcaacct
     7621 ggtcgtcggc atagccctcg cggttctggg cctgtgcatg tccatggccc cggagaggtc
     7681 cacggacctc aacttcgtgg tcctgctcct cggagcctgg ctgatcgtct ctccgtgggt
     7741 cgtcgcgcgc agcgccggca ccggagccat cctcagcaac gtcatcaccg gcgcatgtgt
     7801 gtgcctgttc tcgctcgtcg cgggcgggat gctgatgtcg agaaaccgaa ggtccacctg
     7861 acgtcccgtc gccggtcccg gcggtgaagc ctcggcggtt ccgcgaggcc gcgccgtcgg
     7921 gccggaccgg cacagccgtc cccggcatgc ggagccgtac ggcgcccgcg cctcatctcc
     7981 cggactgtga accggagttg gcgcgggcgt cgtcgccgtg cgcagcggac cggcgcagcc
     8041 acctgcgctc gccgtcctgc cacgcatcgg tgacggcgag cccggcggcg gcggccacgg
     8101 cctcggacgc gcggtgctcg gggtggatgt gggccagcac ggtccgcacc gactgccggt
     8161 cgagccatgc gacgagcccc cgggccgctt cggtggcgat gcctcgaccc tgccaagcgg
     8221 ttcccaccac ccaggcgatc tcggcggtgt cccccggccc gcccggggtg accgtcgcct
     8281 ggaccgtgcc cgtgaggcgg ccctcgtccc gtagccgcac cacccagttg agccaggacg
     8341 cccccgggtc ggggcaaccc ccggccagac gctcgtagcg ggtccggagc gcctccgggg
     8401 tatccgggac gcccccgatg aaggcgtgca gcgccgggtc ggacaggacc ccggccatct
     8461 cctcggcatg gtcgacgcgc agcggcacga ggtcgagccg cgcggtcgcg atggcctggg
     8521 cttcgaagag gttcacgtac gcgatcctct cgccgggccg cgtatcggcc aactcccccg
     8581 ccgcccctgc accccggcac cctccccgga cgaagatgcc cctggccctc cgcgaaggca
     8641 gcggaacgag ggcggcgagc gggagagggg gcagcccaga tgccatgtga gggtgatcac
     8701 agccccagag ggccacccgg gcgtaacctt gcgccatgcc tctgctcgtt cgacgccgcc
     8761 acgtggactt cgtccgcgtc acgagcatgg cctgtcgcgc ttaccgctga cacaggcccc
     8821 ccttctctcc tccccgtgcc cctgcggcgc ccgcctcacc ccggcggatc cgcgatcgcg
     8881 cccacccgcg ccggccgggc atcttccagc ggatggcttc catgtcgtac gtgacctcgt
     8941 cgcagttgcc gatcatcgac ctctccgccg ccgaccgcgg ccccgaggcc cgtcggcagc
     9001 tgcacgccca gctccactcc gccgcgcacg gcgtcggctt cttccagctc gtcgggcacg
     9061 gcgtcacgga cgccgagacc gccgcgctca acgacaccat gcggacgttc ttccggctgc
     9121 cggaggcgga ccggctcgcc atcgacaacg tcaactcgcc ccacttccgc ggctatacgc
     9181 ggatcggcga cgagcgcacc ggcggctccc gcgactggcg cgaccagctc gacataggcg
     9241 ccgagcgccc ggcccgtgtt ccgggaccgg gcgagcccgc ctactggtgg ctcgaaggcc
     9301 ccaaccagtg gcccgccgcg ctccccgagc tgcgcaccgc ggcgctgaac tggatcgacc
     9361 ggctcagcgc ggtcgccgag aagctgctgc acgaactgct cgcctcgatc ggcgcgcccc
     9421 aggacttcta cgacgacgcg ttcggggacc gggcgcacct gcatctgaag ctggtccgct
     9481 atccgggcag cgccgaggac ggcaccgcgc agggcgtcgg cgcgcacaag gactacgggt
     9541 tcctcaccct gctccaccag gacaccgtcg gcggcctcca ggtgcagcgc gaggacggcc
     9601 gcttccacga cgtgccgccc ctgcccggtg ccttcgtggt caacctggga gagctcctcg
     9661 aagtcgcgac caacggctac ctgctcgcca ccaaccaccg cgtggtgagc ccgcccggag
     9721 ccaccgaacg cttctcggtg ccgttcttct acaacccgcg cctggacgcg cacatcgagc
     9781 cgctgacctt cccgtacgcg gcgcacgcgc cgggcgccac cgcggacccg gcgaacccgc
     9841 tgttcgccga gtacggacgc aacgagctca agggcaagct gcgggcccat cccctggtcg
     9901 cggcccgcca ccacgccggc ctgctgctga ccgagcgccc gctggccggt tcggcgctgc
     9961 cggtctaggg ccgaggggcg gtgacgcccg cgacgggccc tcacacccgg cggtccagga
    10021 gcagctccga gagcgcgacc aggtcgtcca cgcgccgcgt caccaggggc gccgcgcgca
    10081 accggtcccg cgcggcggcc acccgggtgc gcgcgtcccg cagcgcgtag gcgcgcccgc
    10141 ccgcctcctc gaccaagtcg gcggcacacc ggacgctcgc ctcgtccggc ggggtcccac
    10201 cgccgaggag cccctccaga cggggcccga gcgagggctg tgcggccatc gcggcgagga
    10261 cgggcagcgt cttcttgccg cgccgcagat cgctgtgcac cggcttgccg gtgacctcgg
    10321 ggtcccccca gattccgagc acgtcgtcga ccgcctggaa cgccaggccc cattcccttc
    10381 cggcctgtgc gagcgcgtcc gcgagccggg gcggggcgcc cgcgaggacc ggcccgagcg
    10441 cggtggcgca gccgagcagg gagcccgtct tgcgggccgc catcgctcgg tactcggcga
    10501 ggcccacggc atgagggccg gtccacggcc gggtctcgaa caggacgtcg tccgcttgtc
    10561 cgtgcaccaa ctcacccagc attactgcca gttgacgcac cgcccgggct ccgcacgcgt
    10621 cgtccgcctc ggcaaccgtg cgcacggcca gggcgaacag ggcgtcgccc gccaggaccg
    10681 cgggcccgct accgaaggcc ttccaggagc tgtcgcgacc ccttctgcgc tcgtccccgt
    10741 ccatgatgtc gtcgtgcatc agggagaagg tgtggatcag ctcgatcgcc acggccgccg
    10801 gcaccgccgc atcggcgctc gctcccactg cctgggtccc gagaaccgcc agggccggcc
    10861 gcaccccttt gcctccactg ccgacaccgg gcgttccgtc cgcgtcgcac cagccgaagg
    10921 cgtgcgccgc gatgcggccg ggctccgggt gcagcccctg tacggccttg cgcagggccg
    10981 gctccacgag ctcgcggcag cgtgcgaggg cggcgaccgc ccggggcgtg gtggtcgtgc
    11041 tggatgctgc cgttgtgcgg ggggagcgca gggagtcggg ggtgtgcaga cctgcctggg
    11101 gggacatgga tgctgctcct gtcgtgggcc gtgcggaggt tgccgtggac atcgcggggc
    11161 ccgcgctcaa ggggtcggca cggcgtccga cgccgggacg cccagctcgg ttcgcgcctg
    11221 ggcgatcatg tctccggcgc gctgcaaccc gatgtcgccg agcgcacgct caagggcgtc
    11281 gagatcggcc gcggtgctcg ccgccggacg gccctgccgg gcctcggcct tcaccaggcc
    11341 gaggcgcgac agcgcttccc cgcgcggctc ccccatcgcc cggaactccg cgagcgcccc
    11401 gcggtagacc tcctcggcct gcgcgtaacg ccccgcgcgg tacagcacgt tgccccgcat
    11461 cttgtggttg tacgccagcg cgccgaccag ctggacctca cggcagagca gttccgcttc
    11521 ggtcagcagc gcgagagccc gctccggttc gccctgggcg gaccgcacat cggccatccc
    11581 gcgcagcgcc cacgcccggc cgcggtcgtc cccggcgtcc cgggctatcc gggccgcctc
    11641 ctcgaacatc gcgagggcgg tgtcgaagga gccggtgttg cggtgcatct gcgcgatgcc
    11701 ttcgagcgcc cacaccgtgt gccgggcctc gccccgccgc cgggcctcgg cgagcagctg
    11761 ctcgtgaaga cggcccacgg cctcgtagtc gccctggatg cgtccggtct cggcgagccc
    11821 ggccagggag tatccgcggg ccacgatgtc accgccctgt tcggccagtt cggccgcttc
    11881 ggccagtcgg cgccgggcca gtgcgagatc gccgcgctgg cgggcaagag tgccaccgct
    11941 ccacaccgcc caggccatcg caccccggtc gccagcccgc tcggccgcgc ggaagctgtc
    12001 ctgccaggcc tgttcggcct cctctacgcg gccgagccgc ctgctcgcct cggcggcggc
    12061 gagggcggca tgggccaact ccagggattt tccgccctgt tcggccagtc gcatttcctc
    12121 gacggccttg gccagcacct cctccagtga ggtgttcacc gacagttcgc ccaggggccc
    12181 ccggtactcg ggcgcggatg ccttgccgta catggttgtc tcgcttcgca tcgtcgtgcg
    12241 gagcacagcg ctccgccttt gatcacgaag ctaggagacg accgggctgc cgggagtcag
    12301 cctcagagcc cgtgtgccgt acatctgaag tcgtacgtcc gacgaggacg tccgccctca
    12361 gcgggacccg tcgaaccgcg ccaagtaggc ttcggcccgc tccggttcca tcagccagtc
    12421 gcggtaaccg accggatccg catagccgtt ggcgaggcga tgcgcgacct cggggtgctc
    12481 atgggcggcc tggaggatgc gaaccacatg gccggccggg ggctgacgca acatcaggtc
    12541 cgtgaaggcg tgcacgtggc gggcctgttc ccagtagtcg tcgaagaccg tccgcatcca
    12601 gcgctcgtcg aagggctgct cctcgcgctt caggatcgcg tcgaggtagg cggcggccgc
    12661 acgcgcggcg ttgttggcgc cctggccggt gagggggtcg ttgaccgcga ccgcgtccgc
    12721 catccccagg acgtactggc cgtcccccag cgaggccacc ccgtgccgga cggtgggcgt
    12781 gatcgcgccg tacaacgcgg cgccgtcatc ggtcggttcg gcccgggcga aacgctcgta
    12841 ctcccatggc gcgtactgcc gcagcagctc caccgcccgg cgcaggccct cgcgcggttc
    12901 cggccggtcc gcccaacagt cgtacgggcc accgaacttg gcctccacga ggaggatctc
    12961 gcagggcccg tgctcggtca gcgcctggag ggcgatcgcg tccccggccg ccgcggcacc
    13021 ggacacccgc agatacgcgt ccgtctcgtc gccacggccc gcgacgccgt cggcgtagaa
    13081 ggccgcgagc gtacgttgcg ggcggtcgta gaccgagcat gccgcgtcac ggccgaagag
    13141 cgacgagagg gcgccgcggc cggcggcgac gaccgtgagg tcgtggcagg cgacgaccgc
    13201 cggtgcgtcg cctgcttcga ccgagccgta cgccacccgg ccgccccgcg actcgaagag
    13261 gtccagccac gcggcgagtt tcaaccgctg gtccaccgag cggacttccc cgtcgtagga
    13321 ggcggtgaag cgtgtcggcc gaccgtcctc ggccgggtcc cagtggcgca tctccaggcc
    13381 gcgcatcacc ggcgcccggt cgtcccagag gttcagcccg gccgcccgct caagcgccag
    13441 ggcgggaccg aacatcagct gtgtcgaggt gacccgaccg gcgcggatct cctgcgatgt
    13501 ccgttccgaa tggagcgtca cgtcgtagtc cgcgccctgc agccccagcg cgagttgcag
    13561 cccggcctgc cccgccccga tgatcgcgat ccgtcgcacg cctgcctcca cccggtcccc
    13621 gccatcgact cccccgttgt acccggtgac gcccgggcct gcccagacgg cctcgggtgc
    13681 taggccgtcg ggtactggcg gagcatccag ttccggtaga gcgccgacag cggacccttg
    13741 tagtcggtgc agcccttggg gcattcggtc gtggtcagat accgccggaa ggccgattcc
    13801 ttgcgccggg ccggctgaac ggcgacgttc gggcgcagcg ctctgatcga gtagccgcgg
    13861 tacccgacca cgacgggctt cgaccccggg acggtggcgg ctgccgctcg cacgaaccgc
    13921 gccgcgactt cgtggtcgct gtggtcgccc ttgggacctg tgccgtagtc ggtgttgcgg
    13981 tagtcgaggg tgcgtacggt cctggcgtgc gcgtccgcga cgagccaggc cagcatggtg
    14041 gtgagttcct tcttgtcgta actcgcgctg cggtccatcg ccgtcatccg gcggatgctg
    14101 cccctttcga gcttgaggag gctctgcccc gcttgggctc gggtgcccga gccgtcgtgg
    14161 atcccgtccg ggagacggag gaaggtgacc cggacaccgg gacggcccgc gggcacccgc
    14221 agcacgaagg cgcggaccgt acgcccggcg tgcctgcggt cctcgcgccg ccactcgttg
    14281 ggcgcccccg cgagcaacgc gtaggcctgg cccacgccct gttcgcgctg ttgcacgtac
    14341 cgggtgccgg ggctgcccgc atcgcccgcg gtgaggtaga cgatgtcgag gcaggccccc
    14401 ttgtcccggt cggcgaccag gtccgggctc atgaagagga ggtcgtcgtc ctcgtgcgcg
    14461 accccggcga ggacggtgct ccggcacggc ggggccgcgg ccgccgccga gtcgacgggg
    14521 acgacgatct gcccccaagc cagaaccgcc atggcccaca ccgccgaagc gcctcgaagt
    14581 ccgagctttt tccgccttgc cgctgtcccg ttcacgggac ggattatcgg cgcatatgtc
    14641 gcaaagatcc cggatttccc tctggcgtgg ctccaggcga tcggcgcggt ccgatcccgg
    14701 cgcctagggt gagtgccgtg accctcctca ccgccgctgt cgtccaagcg ggctcgccct
    14761 tgttcgacac ccccgccgcg ctggccaagg ccctcgacct gatccgcgcc gccgccgccc
    14821 gaggtgccca ggtcgtcgtg ctgcccgagg cgttcctcgg cggctatccc aaggggttcg
    14881 acttcggggt gcgggtcggc agccgcagcc cggagggacg cgatacgttc cggcgctact
    14941 tcgagtctgc catcgcggtc ccgggcgccg agacggacga actcgccgca ctgacagtgg
    15001 agttgagcat ccacgcggta gtcggtgcgg tggagcggtc cggttccacg ttgtactgcg
    15061 tcgccctgtt cttcggcccg cagggttatc tcggcaagca ccgcaagctg atgccgaccg
    15121 ccgccgagcg gctgatctgg gggctcgggg acggctccac catgcccgtg gtcgacagcg
    15181 gccgcggtct gctgggggca gccatctgct gggagaacta catgccgctg ttccgcacca
    15241 cgatgtacgc caaaggcgtc gacatctggt gtgcgccgac ggtggacgac cgggagacct
    15301 ggcaagtgac gatgcgccat gtggcccttg aggggcgctg cttcgtcctg agcgccgccc
    15361 agtacctgct gcgctccgat ctgccccccg acgtccatcc ggtacagggt gacgcgccgg
    15421 acaccgtcct catcggcggc ggcagcacca tcgtctcgcc gctcggcgag gtactcgccg
    15481 ggccgctcag ggacggcgaa ggcatcctgg tggccgacct cgacctcggg gacatcgccc
    15541 gcagccgctt cgacttcgac ccgaccgggc actacgcccg tcccgacctc ttcacgctgc
    15601 acgtggacga aacccccagg ccgccgaccc gggcgggctg aacggtcgcg ggccggaccc
    15661 gaggccccgg ccccacggtg caatgcggcg caccggtggg ccagttgggc ttctcgggcc
    15721 cgacgcaccc gggcccgggc cacctcgccc gtccacgcca ggagcgcgcc ctgcgccgcg
    15781 cgctcccccg gcggccccga ttcaggcgat ctccaccggc acacggaggt cggcgcgcgg
    15841 ccgcgtgtac agacggcccc ggacctcgcc ccgcgccaac cggtccatcg ctgccgggag
    15901 ttcggagaag gggacctcct gcacggccgg cttgagcgcg ccgctcgcga tgaggccgta
    15961 cacctcccgc agttcctcct tgctcgcccc gagtgaaccg acgagctgga cgttgcgcat
    16021 gaccagcgag gcgatcggta tgggcgcgac ggcgccgccg aggcccacga gcaccacgca
    16081 gccacccggt cgaacgcact ccacagcggc ggcggccgtc gacggcacgc ccgcgaagtc
    16141 cacgatgacg tcgggctgtt gggccgtgag ctgccggacg tcctggaagc aggccgtggc
    16201 tccggcctcc gtcgcggggc cgaaggtgga cgggttgaca tcgaccccgt acacggtcgc
    16261 gccgagcagc ttggcgatgc gtacgccgtt gaggccgagc ccgcccagcc ctatcacgcc
    16321 gaccgtgcga cccgggcgga ccgcaccggc cgtgcgcacc gcgtggtagg cggtggccac
    16381 ggagtcggtg gccaccgccg cctccgcgaa ggtcacgttg tcggggatgt ggaccagcgt
    16441 ggagacatgg gcgagctcct gctccgcgaa cgcgccgtcg tgtccgacgc cgggtgcgaa
    16501 gagggcttcc tctatcggat gcgagaccag ggcgatgccc acccggtcgc ccacctcgaa
    16561 gtccctgacg ccgtcgccca ccgaggagat caccccggcg ccctcgtgac ccagggtcac
    16621 cggcgacttg acggtgaggt ctccgaggtc cataccgctc atgatgtgca ggtcggagtg
    16681 gcagagcccg gccgcctcga tgtcgaccac cacccactcc ggcccgggct ccgggtccgg
    16741 aacgatctcc aagttgagcg gccgtcccgc gcctgcgaac cgtatggcct tcatgtgccc
    16801 atccccacct tcacacctgc gtcgtacagt tgttccctga tctggtggtt gaattcccaa
    16861 gcttcgggtg ctttatgcgc gtgattcgaa tcgatggacg aatcaccata tgcccgacgt
    16921 gaacatgcca acggcggccc gcccagcggg tgctgggcgg gccgccgtga cgaggatcag
    16981 cttccgttga cctccagctc gtatatgcgg gcggccggat cggtgttctg ggccgggacg
    17041 aggaccccga ggcgcacgta ccgggccgat ccggtgaccg tgctcgtcgt ggaatcggcg
    17101 gtgttgccgc gcacctgcgc cgccgtggtc caggtggcgc cgtctccgga gacgctcagg
    17161 tcgtagtcct tggtgttcca gtccgcactc tcgccgcccg cgcccgcatg gcgcacggtg
    17221 atcgagctca gcggatggga cgcgcccaga tcgacctgga gggtcttggt gccggacacc
    17281 ttcgaacacc acttgtcacc cgtgccgccg gtgaagctgc cgttgaccgc cttctccggg
    17341 gtctccgtgg cgttgcacga cgccgagccg gtggccggct gccctatcgc gaggtcccgg
    17401 ctgccgccgc tcggcccgta gacctccagc tcgtagatcc gggccgcgtc gctgcccccg
    17461 ccactggtgt tggaggggct ggtgacgacc aggcgcacgt aacgggccga ccgggccgac
    17521 acgggatggt aggtccggct ggagcgcgag ccggtgacgg aggccgcggc ggtccaggcc
    17581 gtgccgtcgg tgctggtctg gatctggaag gcaccggtgt tccagccggt gttctcacct
    17641 cccagaccgg catgcttgat cacgaacgag gacacgttgc gcacggaccc gaggtcgacc
    17701 tggagcgagg ggttcgccgc ggacgagcac cacttgctgt tgttggtgag cgacccgtcc
    17761 accgccttgt cggccgactc cgccgcggca caactcgccg atccggtgac cggcttgccg
    17821 agcgcgaggt cggtgccgag ctccggcgcg gcgggcaccg gggtggcgcc gtcctggaac
    17881 gacggcggca cgtcggaagc gccggtgccc caggtgccgc tcggcgcggc gcccatcgtg
    17941 tagttcaggg tcgcgccgcc cgcgacgtcc gggtagcgca ggtaactgtg gctggtggaa
    18001 gtgccgttga cggcgagcgc ctgcacatag ggcccgctgc cggaactgtt gatggtgatg
    18061 ttcccggccg cccgctggat cagtatggac gggaactggg gcccgtgcac ggccagcgtg
    18121 tccgcccccg gagtcgcggg gtacatgccg agtgcggccc acacgtacca ggccgatgtc
    18181 gcaccgaggt cgtcgttgcc gggcagcccg cccgcgccgg tggtgaacga ctcgtccatc
    18241 accttgcgca cggcgtcggt ggcgcccgcc ggatggcgtg cgtagttgta ggcccacgga
    18301 acaccgtgct ccggctcgtt ccctatgtag taatacggcc tgctctgacc ggcgttgacc
    18361 tcggtgaagt ggtggtcgag acgctgcacg gcggtcccgg ccccacccat ggagttgatc
    18421 aggtcggaga agtcgtacgg caccatccag gtgtactggg aggcattgcc ctcggtgaac
    18481 gtggactggc tcgccgggtc gagcggccag ctccaggagc cgtcgctctg gtgctgctgc
    18541 acgtaggacg actcggagtt gaaggtgttg cgccaccact gggcgcgtcc catatgggtg
    18601 ttgtagctcg atgtgttgcc aagtgccttg gcgaactggg cgacggcgaa gtcggacgcc
    18661 gagtactcaa gtgagtcgga ggggtcgtcg aggtagtgca ggctcgtgta ggtggactgg
    18721 cggccccgga tcgcgccgcc ttgcgccgta ccgccgttgg aagccttctc catcagggag
    18781 agcgcggccg aggtgtcgaa gtcgcgggcc ccgaaggcgt acagactgct gacgatgatc
    18841 gggccggggt cgcccgtcat gacgaagtcc tcgttggtct gctgcgacca cttgggcagc
    18901 agaccgccct gctgtccgtc caggaccatc gacttggcga tgtcactcgc ctcggtgggg
    18961 gccatgagcg cgatgagcga ggcccacgag cggtagatgt cccagcccga gtagttctgg
    19021 tacaccgggc gcgacgcatt gtgcacggcg ttgtcgaagc cccggtagtc gccgttgaca
    19081 tcgctggaga tgttggggct ctgcagcacg tggtacagcg cggtgtagaa cttctgccgc
    19141 tccgtggcgc tgccgccggt gacctggagc cgattgagca tctggttcca ggaggtgtcg
    19201 gccgcggtgc ggatcgcgcc gaagtcccaa cccgcgttct cggcggccac gttggcctgt
    19261 gcgcccgcga tgctcacgta cgacaggccg accttgaact ggaccgtcgc gttggtgctc
    19321 gtgtcgaagg tgacgtaggc gccggtgttg gtgccggagg ccgtggccga gccgtcgctg
    19381 acgctgccgc cggaccaggt gccgaagccg gtcggcgtcc ggtcgaagcg cacgtcgaag
    19441 tagatctggt acgtcttgga cgagccgcag aatccaccgg ccgtcacgct gccggtcagc
    19501 tcattgccgt tgatgtgcac cgacccggcg cggttgcccg tggcgctgcg gccggtgttg
    19561 atcagcaacc gggacgcggt cgaggcgggg taggtcagct tgcccatggc ggtgcgggtg
    19621 gtggcggaca gctctacgtc cgtggcgtag cggtcgaggc gcgtcttgta atagccgggc
    19681 ttggccacct cgttcgcctt ggtgtaaccg gaggcgtagc tcgtccagtt ggtgccgggt
    19741 gaactgccga gcgcgccggt gaccggcagc agcggcaggt cctcgttgtt ggggcagccg
    19801 gcaccgtcga agtgcgtgag gctgaagtcc tcgacggacg tgtccttgta gcggtagccg
    19861 gacggtgagg cggtgggcgt gtccgggccg gcctgtacgc cgccgaaggg cactacggcc
    19921 ccggggtagg tgctgccgcc ggcaccgccg ggcacggggt tgggggcgtt gctgtcgtcg
    19981 gtgccgatga acgggtcgac gtactgggtc agcggaagcg ccgccgcatg ggcgggcacg
    20041 gcggccgcga ggccgacgag tccgagggcg gagagcgcca gcgcactgaa ggcactgacg
    20101 ccccgggagg gacgtcttgg ccggaccgcg ggtccggagg agggcacgga gcggagcacg
    20161 aggggggacc accttctcgc aagggaccgc tcgccgtccg gcgggcggcc tcgggacgga
    20221 ggatgctcga tgtgcatgtg aacgttacca atcaactcag gattgttgag gtgtccctga
    20281 ctacccgtca agggtgaggg gcgaattgca gcctcgtgtt caccgcggca ctccgccccg
    20341 cctccgccac gcctctgcca tatctccgcc acgcctctgc catgaggacc aacttcctct
    20401 caccgtagcg agtttgatga ttcgtcagtc ctgacggatt ccacgctcgg cacgcatggg
    20461 aacgttacca atccgggaga cggtccgagg ccatcggcgc aagcaccgtg cgtgcccctg
    20521 acatgggact ccgtctgcca tcatcgacgc gtcgccgtgc cggatccggg cgcggaccgg
    20581 tcgatgagga ggctcgtgaa gcgcccgacg atgaaggacg tggcccgcgc cgcgggagtc
    20641 agcccgatga ccgtctcgcg ggcggtgtcg ggcgaacccg gcgtctcgcc ggacaccgcg
    20701 gcccgggtgg agcaggccgt acgggagttg ggctaccagc ggaacgacaa cgcccgcagc
    20761 ctgcggcaga aggatccgcg cacgtcgacc atcggcctgg tcgtcgacga cctggccaac
    20821 ccgttctacg cgctgatggc ccgctccgtg gaggacgagg cccaccggcg cggcttcctc
    20881 gtcctggtcg gcagcaccaa cgacgaaccc cgccgagaac gtgaggtcat agccgctttc
    20941 acggcgcgcc aggtggacgg cctcatcctc gtcccgacca acggcggcca cggcttcctg
    21001 aagcagccga tggaggccgg cacacgcgtc gtctgcgtcg accggcctgc gaagggcctg
    21061 gccgtggaca ccgtcaccgt cgacaatcgc gcgggagccg agcgggc
//
