LOCUS       NZ_CP070373            22856 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3530267
            Orig. end                         :: 3553123
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22856
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="12"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22856
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22856
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12856](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12856
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(11..643)
                     /locus_tag="GWQ54_RS15575"
     CDS             complement(11..643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433096.1"
                     /locus_tag="GWQ54_RS15575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA polymerase ligase N-terminal
                     domain-containing protein"
                     /protein_id="WP_167161934.1"
                     /transl_table=11
                     /translation="MARKHEARDGLSEYSRKRDFSKTPEPAGEAAQGNGRGPVFVVQIH
                     DASTVHFDFRLEVDGVLKSWAVPKGPSGDPHDKRLAMPTEDHPMAYADFEGVIGEGYGA
                     GTVIVWDSGTYRSLATDRHHHEVPFAEALEHGHVSFWMEGTKLRGGYALTRIRRPQDGD
                     REAWLLVKEDDGHASAHSTTEPTRARSALSGRTLKQVADEAAKQTSP"
     misc_feature    792..807
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     misc_feature    complement(819..832)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.49"
                     /tool="antismash"
     gene            830..1060
                     /locus_tag="GWQ54_RS15580"
     CDS             830..1060
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375137.1"
                     /locus_tag="GWQ54_RS15580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chaplin"
                     /protein_id="WP_167162378.1"
                     /transl_table=11
                     /translation="MRTAIAAAALAVAGVLAGGASAVADAGAQGVAAHSPGVASGNLVQ
                     IPVHVPINICGNTISVAGALNPAAGTTCINS"
     CDS_motif       830..886
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRTAIAAAALAVAGVLAGG"
                     /locus_tag="GWQ54_RS15580_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       887..1060
                     /prepeptide="core"
                     /locus_tag="GWQ54_RS15580_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="5161.8"
                     /monoisotopic_mass="5158.7"
                     /core_sequence="ASAVADAGAQGVAAHSPGVASGNLVQIPVHVPINICGNTISVA
                     GALNPAAGTTCINS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRTAIAAAALAVAGVLAGG"
                     /leader_location="[829:886](+)"
                     /alternative_weights="5179.8"
                     /alternative_weights="5197.8"
                     /alternative_weights="5215.8"
                     /alternative_weights="5233.8"
                     /alternative_weights="5251.9"
                     /alternative_weights="5269.9"
     gene            1298..2713
                     /locus_tag="GWQ54_RS15585"
     CDS             1298..2713
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950856.1"
                     /locus_tag="GWQ54_RS15585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_167161932.1"
                     /sec_met_domain="Aldedh (E-value: 3.2e-136, bitscore:
                     453.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQHKSSFATVSPATGETVAEFDAIEGEEVDARLEAANRAFDAW
                     RRRPIEERAAVVGRAGALMRERKEELAQLITLEMGKLIAEARGEVDLAASILEYYAENG
                     PDFAAAEPLDVDEGEAYLLNEPLGVLLGVMPWNFPLYQVVRFAGPNLVLGNTVLVKHAG
                     ICPQSALALESLFFDAEAPEGVYTNLFVGHEEISRIIDSPVVRGASLTGSEKAGAQVAE
                     RAGRNMKPSLLELGGSDVFIVLDGERLERTVGAAVAGRMANTGQSCVASKRFIVLADVY
                     DDFVAGLRRAFEGLRPGDPADESTTLGPLSSERAAADLVDQIRETVEQGAELVTGGRRI
                     DRPGAFVEPTILTGVKPGMRAYAEELFGPAAVIHRVADEEEAIALANDSQYGLGGTVFC
                     ADVERGRKVAERVETGMVWVNHPTSTQPDLPFGGIKRSGYGRELSKLGMQEFVNRKLVR
                     VLPPDAELRGIAG"
     gene            2869..3696
                     /locus_tag="GWQ54_RS15590"
     CDS             2869..3696
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960983.1"
                     /locus_tag="GWQ54_RS15590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_161245084.1"
                     /transl_table=11
                     /translation="MTAVPTITLNNGVRIPQLGFGTFQIPKDETRETTLAALEAGYRHI
                     DTAQMYGNEKEVGQAVRDSGLDRGDVFVTSKLNNDAHAHDDALAAFDRTMDELGLDHLD
                     LFLVHWPLPGKGDFTETWKAMEEIYGSGRAKAIGVSNFQPHHLRRLMESGVVVPAVNQI
                     EVHPYLTQDDVRAFGAEHGIATEAWSPIAQGKVLDDPAIKRIAERVGKSPAQVTLRWHI
                     QRGDIVFPKSVTQKRIEENFDLFGFELTEGDLGEISALNRDERTGPDPDRFNG"
     gene            3870..4502
                     /locus_tag="GWQ54_RS15595"
     CDS             3870..4502
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS15595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167161930.1"
                     /transl_table=11
                     /translation="MATASITGAVVTVNVEGATPLRLDMSLQRHSYRHCATSTVAGEIN
                     SLLYASVDDATVTAEAVEVGEQIEALLAKAKGSWKALFGKTLTVGSGRTYLVDNSGLNP
                     NGSPNHFFVTGGTGVWSKVSQADYVAARDVRRAEEAITARRGRGDTYDYLDSKKLNEKR
                     AEPGGATNPVVQAVQAARVSIAAASADDAALIAASGRKDLVTLIRSV"
     CDS             4573..4809
                     /gene="allorf_3534840_3535076"
                     /locus_tag="allorf_3534840_3535076"
                     /protein_id="allorf_3534840_3535076"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSARRGRPEAEVSPGTRGARSAPGGTGDSHGRRPKRPAPPRGSPL
                     RPAELQPAGLPFGGIGSGCLRAGCAGARWVNSC"
     CDS_motif       4573..4620
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSARRGRPEAEVSPGT"
                     /locus_tag="allorf_3534840_3535076_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4621..4809
                     /prepeptide="core"
                     /locus_tag="allorf_3534840_3535076_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.60"
                     /molecular_weight="6095.9"
                     /monoisotopic_mass="6092.2"
                     /core_sequence="RGARSAPGGTGDSHGRRPKRPAPPRGSPLRPAELQPAGLPFGG
                     IGSGCLRAGCAGARWVNSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSARRGRPEAEVSPGT"
                     /leader_location="[4572:4620](+)"
                     /alternative_weights="6113.9"
                     /alternative_weights="6131.9"
                     /alternative_weights="6149.9"
     gene            4844..6124
                     /locus_tag="GWQ54_RS15600"
     CDS             4844..6124
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345612.1"
                     /locus_tag="GWQ54_RS15600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_240361985.1"
                     /transl_table=11
                     /translation="MRAAVAAGPPPGPARPEFWRSPIRGPWLTAVFGLALLCGVSVLFV
                     TGLLSYAAYDPDLARINDQTPDKGVLGFYLFTWPTSPYWGYRLSQGVHVTLGIVLIPVL
                     LAKLWSVIPRLFEWPPVRSVGHALERLSLLLLVGGAGFEFATGVLNVQLHYVFPGSFYV
                     LHFYGAWVFIGAFVVHVVFRLRRAVIAVVKGPRAEEQHRARPLATAGPSLVAPRPAEPT
                     MSRRGAVLLVGAGSAALLVVTMGQSIGGWMRRTALLAPHGQDPGSGPNGFQINKTAASV
                     GVRPSDIGPAWRLTVRAGGRQTVLTRDELYALPRRTVELPIACVEGWSTPDQRWGGVRL
                     VDLAALVGVTHDVPRVLVESVQRGGSFGSVVLAANQVRDTRSLLAVEVNGADLSPDHGY
                     PARIVVPNAPGVHHTKWVTRLTFGEPT"
     gene            6121..6618
                     /locus_tag="GWQ54_RS15605"
     CDS             6121..6618
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714412.1"
                     /locus_tag="GWQ54_RS15605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167161926.1"
                     /transl_table=11
                     /translation="MNRFRSRYGASPLHLTAVLCSFALALYAGVRLLRGDTLGVVLWFV
                     GAALLHDLVLLPLYATADRALQRLMTATGRSGTHPVGDRVVGVNHVRVPAFVSGVLLLV
                     WWPLILGQVDGFTAATALPSDVFLGRWLLLTAALFAVSALCASARLWRRSSRERRRRDA
                     TG"
     gene            complement(6634..7140)
                     /locus_tag="GWQ54_RS15610"
     CDS             complement(6634..7140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562746.1"
                     /locus_tag="GWQ54_RS15610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_193587977.1"
                     /transl_table=11
                     /translation="MTDGSEEMRYEETPRPDEGPLSTEDLAAGRQQDTEAEAPGPAGGA
                     PTYPGEATAGREDRQEDAGDRAPGHARAEAEPAEDDEPLLGSEQEEFRARWQQIQSRFV
                     DDPQDSVNAADQLVAETMQALATTFSAHKRDLEGQWHRGEEVPTEDLRVALQQYRSFFN
                     RLLST"
     gene            complement(7198..7755)
                     /locus_tag="GWQ54_RS15615"
     CDS             complement(7198..7755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540661.1"
                     /locus_tag="GWQ54_RS15615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167161924.1"
                     /transl_table=11
                     /translation="MSLTVVIIVIAVVVVLIACAVAARLATVRRRRLQERFGPEYERTV
                     DEQDSRRAGEQELRERQERHDALDIKPLPAAARERYSQDWARVQEQFVDRPDDAVHDAD
                     RLVTTLMSERGYPTEGYEQQLKDLSVEHGETLEHYRAAHDINDRSGRHQATTEELRGAM
                     VHYRALFEELLHNGDRPGRSTA"
     gene            complement(8040..9338)
                     /locus_tag="GWQ54_RS15620"
     CDS             complement(8040..9338)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004944772.1"
                     /locus_tag="GWQ54_RS15620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_167162376.1"
                     /transl_table=11
                     /translation="MLWTAVGVVALAFLIGLEITARHYGERGPLSTQVREVLFAPKPGP
                     LYGGLALMMVVLTWRQRFVAAGVAIGVDAVFVLGRWACGVRVPEGHLFGNGALWAMLGC
                     AVFAITRRTGTERVLLLKGVGLGLLLVTGRKIGDSWLLITSKTRPTVLDPYVATADHAL
                     GNPSWLAGRALDAIGPAGSNLLGLIYAQLAVAAIVVALYQLRKVAAERRFPRHHLVRTF
                     LLIGLLGPAIYMIFPVVGPVFAYGPGASGTGGVEWSVANLWPHTPPPITIPHPVPYDGI
                     TPRNCMPSLHTAWATAIFIHTRTGPRLLRYAGTFWLIATLAATLGFGYHYGVDLVAGVV
                     FSLTVEAAMRTFDRGWDRSGLRLVAHGTAVFTLLLVSYRWLPVHMAARPWLFGPLVLLA
                     MGSVILGYLRTTRPWTSPDTAPALLPERQPEPV"
     CDS             9370..9597
                     /gene="allorf_3539637_3539864"
                     /locus_tag="allorf_3539637_3539864"
                     /protein_id="allorf_3539637_3539864"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTWRIRALLGESPGINCSADVLVAGGQAGAGACRASIMPPPDSGA
                     FAGIGSAPPPARTTGVPRISDPVTLAGFRI"
     CDS_motif       9370..9447
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTWRIRALLGESPGINCSADVLVAGG"
                     /locus_tag="allorf_3539637_3539864_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9448..9597
                     /prepeptide="core"
                     /locus_tag="allorf_3539637_3539864_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.30"
                     /molecular_weight="4635.3"
                     /monoisotopic_mass="4632.4"
                     /core_sequence="QAGAGACRASIMPPPDSGAFAGIGSAPPPARTTGVPRISDPVT
                     LAGFRI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTWRIRALLGESPGINCSADVLVAGG"
                     /leader_location="[9369:9447](+)"
                     /alternative_weights="4653.3"
                     /alternative_weights="4671.3"
                     /alternative_weights="4689.3"
                     /alternative_weights="4707.3"
                     /alternative_weights="4725.4"
                     /alternative_weights="4743.4"
     gene            9667..9867
                     /locus_tag="GWQ54_RS15625"
     CDS             9667..9867
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240677.1"
                     /locus_tag="GWQ54_RS15625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6229 family protein"
                     /protein_id="WP_053728018.1"
                     /transl_table=11
                     /translation="MPQTSVPASAVLNAWLSGAESAYGQLNPAGPLYVGGAAAEAALTD
                     SSDSLYGFCSSPSGSHGSWCC"
     CDS_motif       9667..9738
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPQTSVPASAVLNAWLSGAESAYG"
                     /locus_tag="GWQ54_RS15625_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9739..9867
                     /prepeptide="core"
                     /locus_tag="GWQ54_RS15625_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="3973.3"
                     /monoisotopic_mass="3970.8"
                     /core_sequence="QLNPAGPLYVGGAAAEAALTDSSDSLYGFCSSPSGSHGSWCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPQTSVPASAVLNAWLSGAESAYG"
                     /leader_location="[9666:9738](+)"
                     /alternative_weights="3991.3"
                     /alternative_weights="4009.3"
                     /alternative_weights="4027.3"
                     /alternative_weights="4045.3"
                     /alternative_weights="4063.4"
                     /alternative_weights="4081.4"
     gene            10001..12856
                     /locus_tag="GWQ54_RS15630"
     CDS             10001..12856
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240676.1"
                     /locus_tag="GWQ54_RS15630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_167161922.1"
                     /sec_met_domain="DUF4135 (E-value: 2.7e-71, bitscore:
                     239.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7e-38, bitscore:
                     129.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANAVVPGAPEETEHFARPVRSIARPWRDQLACALAELPSLDATE
                     RDVILEAGHTALLRSLHAKLSRLFLIELHALRLSGPAAGAGVAPGPGSASGSESGRAIW
                     DAFVEQAGAEGYLDGLSDRYPNLARRIATVARLSVTATAEFAERLAADRDLLAPLLGAP
                     AGRVRAVAFGAGDSHHGGLTVSRVDFAGGTVMYKPRPSEADVALGALLDDLFTGLPGAP
                     APDRRIRVPATLARDGYGWAEFIGHRYCADGAELAVFYRNLGHWLAVLRFTGGTDMHAE
                     NMIAAGPVPVIVDAETLFDAPAPFPPSGRGDAVDVAAAAIRRTVLRTGLLPVRGTGFAL
                     GGVDISGIGALPGQQPLIPHPVIADGGTATARFEVDLVAMPVAGNHPAATPVLSTYWDR
                     VLAGFREMTAHLRRPGLDPHRLLARFEGARARRILRPTQAYVDIGRMLWHPASLHDEAA
                     AVERARDILRRNADALPGAPTDRATIDGEIADLLVGDVPMFNFTVDAAAVRATVEDWRD
                     ADLAFEESVIQDALVGAYLNERSLPARVQEAAHAPHARDRERRRRELAAQMVRRLCDGA
                     VRGEDGTVTWISPVFTPAGWSIRVLPADLYTGQGGVALTLAEYACEVRAGRADEVPGVP
                     ETFEGALRVLISTEDRTPTPSAGAFSGAASQVWTWLALHRVLGEDWMLERAAERALLLT
                     GGPLVDEDVEVDLLNGVAGAVVPLLDLATATGQARWLDAAAHIGHRLGKLAVSDAGGAR
                     WPTRLNPEGIGGFAHGATGIGWALTRLALSEAGSAAERDDWKRLAARAFAFQESLYRPA
                     DGNWLDVRVGAEEDFFTSWCHGSAGIGIGMLDLHRRTGDPAHLDMARRAAGACAAEGFG
                     WSHTLCHGDLGLWEFLTSIGSGDARDLDAEILSGLEQRGPVGGLAREAFSPSLMSGLAG
                     VVHTLLRMHPDADLPNPLLLD"
     gene            complement(12890..14122)
                     /locus_tag="GWQ54_RS15635"
     CDS             complement(12890..14122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180574.1"
                     /locus_tag="GWQ54_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatic acid exporter family protein"
                     /protein_id="WP_161245091.1"
                     /transl_table=11
                     /translation="MWEFTDPLFDFARRRREPAVVQTLRSTAAAVISYVVALHLSSEPA
                     PLTAPLTALLVVQVTLYTTLVTAVRRVNSVVVGVLLAVGFSSLVGLTWWSLGLIILAAL
                     VVGRFVKVGEFVPEVAISAMLVLGVTRVSATAWDRVLETLIGAGVGMLFNVLLAPPVWV
                     DSAGGAIEELAARMRRLLVDLGDEVGGHTPVAQAAARLHEARRLDHDIAQVDASLRQAE
                     DSLRLNPRVKEGLLSRVVLRTGLDTLEISAVVLRVVCRSLTDLAKERTEEHLFDPEVGL
                     ALRDVFEHLARAIESFAVLITTQVSTNAEEAEQRLTDELTAGRASRDRVADLLLAEVQR
                     HPRQWQLHGALLAEVDRILDELDVEKRSQRLVEELDRLSREQRRRWHLLRRVRSRTQQA
                     LRLPEPEDRRS"
     gene            14293..16455
                     /locus_tag="GWQ54_RS15640"
     CDS             14293..16455
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118352.1"
                     /locus_tag="GWQ54_RS15640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TerD family protein"
                     /protein_id="WP_167162374.1"
                     /transl_table=11
                     /translation="MVHALEPLVVRHTHRLPAPRGAAGQGGVAARQFDAALMSVGFKLS
                     AELLGHLSALSEGTVVDTAVRTLDTLRAMVGDHVRHNAYFIDFPAHVPDTYAFWQQCVA
                     DAVDRGVAVAGLSDGVVDLLTLPAYGTYQHSYAEMLAAHGELLAASGDRLTVLHLGEAP
                     DDEITALYLALAGSAAPLGDGGLPDLEVLAGHCVHGPQPEAIPVRENRAVVNRARVEAG
                     ADPLLDTVTDVLRLACGLSDGDVTLVQPTRFRSPSRRVRRVLLAGLDAVVAANPAKLAD
                     VSAHREAFKRLGERLHAHEYAARWPHAADVFAVARGEKRARSFDSRVEELLAADDVLGA
                     ARLLESAPGKLFRCLDRLLRACATDAERDAVARAAARLAPEVSGRVLLSVREHFHNRAR
                     GSGARRVFVNRLGRAWAADESRSPLPEAVRARLVAALDAETSRRLPAPGHLLIDPDVLD
                     VALPLSGRATAPGFGVLPRGSLSPVDGELLRFFVYWKQTSDTTDFDLSALMLNSVYETV
                     SWLSYTALTEVEGEHSGDITEAPDGASEFINLRLGAVRGTYIVPQVNIFSGEGFEEVEE
                     SFFGFMLREGDQRGRPFEPRTVRMKSQLRGPGRVALPLAFIRGEDGRWRAKWLHVYLKG
                     TPSANRVEGNRVSVAALVRGFVERDHLTVRHLTGLMADRGDVTTLWDGKTVPQGPVTYI
                     GLERPDGLHPDSCVITPENLGDLVPE"
     gene            16654..17244
                     /locus_tag="GWQ54_RS15645"
     CDS             16654..17244
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957845.1"
                     /locus_tag="GWQ54_RS15645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_167161920.1"
                     /transl_table=11
                     /translation="MVRVRKMNGTDVEAVSAIRVRGWQSAYAGILPRSYLEAMTVEDDA
                     ARRREWFSLPHRQSVDLVAVDGGEPVGWINYGPSRSEVPEVPDERTGEINALYVRPGLT
                     GRGIGRGLLDEAHALMQSQEFRAVLLWVLADNQGARRFYERAGYRADGHTQADVYDGVA
                     VPELRYRRACWSGPRTGVADSTVGHTDASGSAR"
     gene            complement(17251..17490)
                     /locus_tag="GWQ54_RS15650"
     CDS             complement(17251..17490)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167161918.1"
                     /transl_table=11
                     /translation="MRMRTTLAAGALAIAAVLGSTGTALAHDRDDHHSGGETSACGSFA
                     GAGGGHAAWGSGCMHSQWEGRYPGRGFHHRLNGF"
     CDS_motif       complement(17464..17490)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRMRTTLAA"
                     /locus_tag="GWQ54_RS15650_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17251..17463)
                     /prepeptide="core"
                     /locus_tag="GWQ54_RS15650_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="6883.4"
                     /monoisotopic_mass="6879.2"
                     /core_sequence="GALAIAAVLGSTGTALAHDRDDHHSGGETSACGSFAGAGGGHA
                     AWGSGCMHSQWEGRYPGRGFHHRLNGF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRMRTTLAA"
                     /leader_location="[17463:17490](-)"
                     /alternative_weights="6901.4"
                     /alternative_weights="6919.4"
                     /alternative_weights="6937.4"
                     /alternative_weights="6955.4"
                     /alternative_weights="6973.5"
                     /alternative_weights="6991.5"
                     /alternative_weights="7009.5"
     misc_feature    17482..17495
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.49"
                     /tool="antismash"
     gene            complement(17633..20269)
                     /locus_tag="GWQ54_RS15655"
     CDS             complement(17633..20269)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167161916.1"
                     /transl_table=11
                     /translation="MQLDAVIAQLTFRERFSRKRVRFERDAGALVLQIEGGSDPVRQWL
                     TRLLKEYRGIVPVNNPSDVEESDPERQVLEQLQAVAEGCGYGGIVARGLPIVFPRFAAA
                     RAALYDRQQTGDHSHARRMGALKRQIEEAIAQERRHSMPQARTRLDPLIQDPYVTQQLG
                     GFLGLLLKIANALRLPCYRTVRWFRKRRFPGLRTFEAVCEELDGWSARPAHEKQRLLVE
                     ALLADVDAHYGVLRRLNRVRRPVILLPDVDTIPARRIIRDRMLEALSGTAKDLRVHPVV
                     ITTSRPGEADPLTGGRPAVPADCLGEEIPGRFRERREVGASRAGGGSEPLPSLLVQIVL
                     DDAAGPRPAPGVRLLGPVTVGVTAVALIAAGLGGYVTFFREPAACGRGLEIHGGECVGV
                     SDGTGVFMPDVKGMPQVFERIAEQNKAVAGRKHATVALLIPMQSASPAVQRQILSEVQG
                     AYLAQVAANGADSVKPAIRLVLANPGDGYGRWRGTLDQLTSQEPDLRVVMGFNLSLDKT
                     KEALTYVTNTLHLPAVASVVTADDFANPEGTDTVPYPGLARVVSTSREQARALLAFDPE
                     LAGSETALVADDRPGDDYDRSLRDAFAEARRNEGGRGVQDMRFESPGVEEAGVTPNEFE
                     DFAGNICRSNTHVIYFAGRAFHLKLFVEKLATTYCREKASYTVITGSDATTLDERLDDH
                     DRALLRGDPGSGKPSVSIRYAAPAHPDAWSTELAKWQNDPRTKGQDPPLYLREAQDSMN
                     ALRRGIADQPGPIGPVNLDDGRTIVTYDVVLTASRALARAVHTSGLEVPTADRVVRDLG
                     KLNSDLRVRGAGGWICLTNAGNPYNKALSVVRLDPGSHKLVFEGVAWPTGHAPGHDDNC
                     VVPVHPD"
     misc_feature    complement(20377..20390)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.57"
                     /tool="antismash"
     gene            complement(20469..20906)
                     /locus_tag="GWQ54_RS15660"
     CDS             complement(20469..20906)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236345.1"
                     /locus_tag="GWQ54_RS15660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_167161914.1"
                     /transl_table=11
                     /translation="MAKDSSLKAVGWARSLPLTSSVKEARDWTREHLATLDWARTSPDV
                     VDSVLLTVSELVTNAQVHARSTAQLILTWDEECLHVTVHDASPQLPEQRDPEADALGGR
                     GLLLIDVLADDWYAYPCPRGKSVTACFQPPTPARPEAVGGG"
     misc_feature    complement(20859..20873)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.2"
                     /tool="antismash"
     misc_feature    20860..20874
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.2"
                     /tool="antismash"
     gene            complement(20979..22214)
                     /locus_tag="GWQ54_RS15665"
     CDS             complement(20979..22214)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971002.1"
                     /locus_tag="GWQ54_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_167161911.1"
                     /transl_table=11
                     /translation="MTSFVTNPTGAAPQEQTYRVVLIEDDLADAVLVEELLLDTGLRFE
                     LTTCTSLAGARTDPALRTADCILLDLHLPDVSGTKAVAAVRAAAPHTAVIVLTGLSEAQ
                     AGSDAMAAGAQDYLVKGKVDADLLHRAVRYAVYRSQTELANAQTQAATLRAEENSRLER
                     GLLPQPLLSTSAVTVTTRYLPGTELALLGGDFLDVVEGDDGLLHAVVGDVSGHGPDAAA
                     LGVCLRIAWRSLILGGHRGRELLHLMERILIAERGDRPLFATCALLTLDHGAATAELHL
                     AGHHGPLLSTDRGSREITAAHGIALGIDPRVSNWPASLIPLPAAGALTLYTDGLTEGRN
                     GSARGRLGVEGLLTLIDRLPQSDPAAHIDLLIKETSALNAGRHSDDVAVLRLDWRQPAV
                     PGPRSAPGSVRG"
     misc_feature    complement(22368..22380)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
ORIGIN
        1 ggcgtcgcgc tcacggcgac gtctgcttcg ccgcctcgtc cgcgacctgc ttgagggtgc
       61 gcccgctcag cgcggaccgg gcgcgggtgg gctcggtcgt gctgtgcgcg gaggcgtgcc
      121 cgtcgtcctc cttgaccagc agccaggcct cgcggtcgcc gtcctgcggg cgtcggatcc
      181 gggtcagtgc gtagccgccg cgcagcttgg tgccttccat ccagaacgag acgtgcccgt
      241 gctccagcgc ctcggcgaag ggcacctcgt ggtggtggcg gtcggtggcc aggctgcgat
      301 aggtgcccga gtcccagacg atcacggttc cggcgccgta cccctcgccg atgacgccct
      361 cgaagtcggc gtacgccatc ggatggtcct cggtcggcat cgcgagccgc ttgtcgtgcg
      421 ggtcgccgga cggccccttg gggacggccc aggacttcag caccccgtcc acctccaggc
      481 ggaagtcgaa gtgcaccgtg ctcgcgtcgt ggatctgcac cacgaagacc ggcccccggc
      541 cattgccctg ggcggcctcg cccgcgggct ccggggtctt cgagaagtcg cgcttgcggg
      601 agtactcgct cagcccgtcc cgcgcctcgt gcttcctggc catggtgggc acccttccgc
      661 ggaccatttc ataccggtgt gcggccagcc gccacccgga ccggggggac gaccgccact
      721 cgtcgagggc gacacgcgac cggtgtggtg aatgcggctt tttcgatcat gctgcggggt
      781 ctcatatcgg ctcaacgttc tttcgaccat gtgggagaca gacatgcgta tgcgaaccgc
      841 gattgccgcc gcagccctcg ccgtggccgg tgtcctggcc ggaggtgcca gtgccgtcgc
      901 cgacgccggt gcacagggtg tcgccgctca ctcgcccggc gtcgcctccg gcaacctcgt
      961 ccagatcccg gtgcacgtgc cgatcaacat ctgcggcaac accatcagcg tggccggcgc
     1021 cctcaacccg gccgccggca ccacctgcat caactcctga cgcacccctg gccggggtcc
     1081 gcacggcgga ccccggtgag cccgtagtcc tcgaccccgc cccggtgccg gccctctggt
     1141 cggcaccggg gcggggtcga ggcgtctcgg cctcgcggcg ggccaccgcg ccccgccgat
     1201 ccaggacggt ttgcgccacc ggaaggcggt tacccgtgac agggacggaa cgtgccattc
     1261 cgccgcactt cctccccgtt cccgttctgg agattgcatg tcagaccagc acaagagctc
     1321 gttcgcgacc gtgagcccgg ccaccgggga gaccgtcgcg gagttcgatg ccatcgaggg
     1381 cgaagaggtc gatgcccggc tcgaagcggc caaccgtgcg ttcgacgcat ggcggcggcg
     1441 gccgatcgag gagcgggccg ccgtcgtcgg ccgggccggc gccctgatgc gcgagcgcaa
     1501 ggaggagctg gcccagctca tcacgctgga gatgggcaag ctcatcgccg aggcgcgcgg
     1561 cgaggtggac ctcgccgcgt cgatcctgga gtactacgcg gagaacggcc ctgacttcgc
     1621 cgccgccgag ccgctcgacg tcgacgaggg cgaggcgtac ctcctcaacg agcccctcgg
     1681 cgtcctcctg ggtgtcatgc cgtggaactt cccgctctac caggtggtcc gcttcgccgg
     1741 ccccaacctg gtgctcggca acaccgtgct ggtcaagcac gccgggatct gcccgcagtc
     1801 cgcgctcgcc ctggagtcgc tgttcttcga cgcggaagct cccgagggcg tctacaccaa
     1861 tctgttcgtg ggtcacgagg agatctcgcg gatcatcgac agcccggtcg ttcgcggcgc
     1921 ctcgctgacc ggcagcgaga aggcgggcgc gcaggtcgcc gagcgggccg ggcggaacat
     1981 gaagcccagc cttctggagc tgggcggcag cgatgtcttc atcgtgctcg acggggagcg
     2041 gctggagcgc accgtcggcg ccgcggtggc gggccggatg gcgaacaccg gtcagagctg
     2101 tgtggcctcg aagcgcttca tcgtcctcgc ggacgtctac gacgacttcg tggcgggtct
     2161 gcgccgcgcg ttcgagggac tgcgaccggg cgaccccgcc gacgagtcga ccaccctggg
     2221 tccgttgtcc tccgagcggg ccgccgccga tctggtcgac cagatccgag agacggtgga
     2281 gcagggtgcg gagctcgtca ccgggggccg tcggatcgac cgcccgggcg ccttcgtcga
     2341 gcccaccatc ctcaccggcg tcaagcccgg gatgcgcgcc tacgccgagg agctcttcgg
     2401 cccggccgcg gtgatccacc gcgtcgccga cgaggaggag gccatcgcgc tggccaacga
     2461 tagccagtac ggcctcggcg gaaccgtgtt ctgcgccgat gtggagcgcg ggcgcaaggt
     2521 ggcggagcgg gtggagaccg gcatggtctg ggtcaaccac ccgacgtcga cgcagcccga
     2581 cctccccttc ggcggcatca agcgctccgg ctacggccgc gagctctcga agctcggcat
     2641 gcaggagttc gtgaaccgca agctggtccg cgtcctgccg cccgacgccg aactgcgcgg
     2701 aatcgccggc tgatcctccc gagcgacgac gcccgggccg cgaagcccga gcgccaacac
     2761 ccgagcgtcg acgcgcgagt ggcgcggccc gagcgccaac gcccgagccg cgaagtcccg
     2821 aaccacgaca tcgatcatca acaccggtca cgagatcagg agagcagcat gacggcagta
     2881 cccacgatca ccctcaacaa cggtgtgcgg atcccgcagc tcggcttcgg gacgttccag
     2941 atcccgaagg acgagacccg ggaaaccacg ctggccgcgc tggaggccgg ataccggcac
     3001 atcgacacgg cgcagatgta cgggaacgag aaggaggtcg ggcaggcggt ccgggattcc
     3061 gggctcgacc gcggcgacgt cttcgtgacc agcaagctca acaacgacgc ccacgcgcac
     3121 gacgacgcgc tcgcggcgtt cgaccgcacc atggacgagc tcggcctcga ccacctcgac
     3181 ctcttcctcg tccactggcc gctgcccggc aagggtgact tcacggagac gtggaaggcc
     3241 atggaggaga tctacggctc cgggcgcgcc aaggccatcg gcgtctccaa cttccagccg
     3301 caccacctgc gtcggctcat ggagagcggt gtggtcgtgc ccgcggtcaa ccagatcgag
     3361 gtgcacccct acctcactca ggacgacgtc agggccttcg gtgccgagca cggcatcgcc
     3421 accgaggcgt ggtcgccgat cgcgcagggc aaggtgctcg acgacccggc catcaagcgg
     3481 atcgccgagc gcgtgggcaa gtccccggca caggtcacac tgcgctggca catccagcgc
     3541 ggggacatcg tgttccccaa gtcggtgacg cagaagcgca tcgaggagaa cttcgacctg
     3601 ttcggcttcg agctcaccga gggcgatctc ggagagatct ccgcactcaa ccgcgacgag
     3661 cggaccggtc ccgacccgga ccggttcaac ggctgaggca tcaacgtgca gccgcctacg
     3721 ccgagttgag gacggggtcg cagaccatgt gacccaatca gtggatatgc agggacggtt
     3781 cgggtgatct tggcatagtg gtcgtgatgt gaagccgagc tcggcgggcc catcaggggc
     3841 ccggcgccgg cccgcgaggg agcttcgcca tggccactgc atcgatcacc ggagccgtcg
     3901 tcaccgtcaa cgtcgagggc gcgacgccgc tccggctgga catgtccctg caacgccact
     3961 cctaccggca ctgcgccacc agcacggtcg ccggggagat caacagcctg ttgtacgcga
     4021 gcgtcgacga cgccaccgtc acggccgagg ccgtggaggt cggcgagcag atcgaagcgt
     4081 tgctcgcgaa ggccaagggc agttggaagg ccctgttcgg caagaccctg acagtcggtt
     4141 cgggacgcac ctatctggtg gacaacagcg gcctcaaccc caacggctcg cccaatcact
     4201 tcttcgtcac cggtggcacg ggagtgtggt cgaaggtctc ccaggccgac tacgtcgccg
     4261 cccgcgatgt gcgccgcgcg gaagaggcga tcaccgcgcg gcgcgggcgg ggcgacacct
     4321 acgactacct cgactcgaag aagctcaacg agaagcgggc cgagcccggc ggcgccacca
     4381 accccgtggt gcaggcggtg caagcggcgc gcgtcagtat cgccgctgcc tccgccgacg
     4441 acgcggcact catagcggcc tcgggccgca aggacctcgt cacgctcatc cgcagcgtct
     4501 gaggaggcgg aggcggccgc ccccggcccg gcgggctggg ccgttcggct gcctctccgg
     4561 tgcgcgtgcg gagtgtcagc gcgccggggc aggccggagg cggaagtttc acctggaacg
     4621 cgcggcgctc ggtcggcgcc tggtggaaca ggggattccc atggacggcg gccgaagcga
     4681 ccagcccctc cccgaggatc cccactccgc cccgcagaac tccagcccgc aggactcccc
     4741 ttcgggggca tcggctccgg gtgcctccgc gccgggtgcg ccggcgcacg gtgggtcaac
     4801 tcctgctgat tccgggcgag tcgagccccg cggatggcgg cggctgcgtg cggccgtcgc
     4861 ggcgggaccg cctccgggtc cggcgcggcc ggagttctgg cgcagcccca tccgcggccc
     4921 gtggctgaca gccgtgttcg gtctggccct gctgtgcggg gtgagcgtcc tgttcgtcac
     4981 cgggctgctg tcgtacgcgg catacgaccc cgacctggcg cggatcaacg accagacccc
     5041 ggacaaaggg gtactgggct tctatctgtt cacctggccc acgtcgccgt actgggggta
     5101 ccggctcagc cagggtgtgc acgtcacact cggcatcgtg ctgatcccgg tgctcctggc
     5161 caagctgtgg tcggtgatcc ccaggctctt cgagtggccg cccgtgcgct cggtcggcca
     5221 tgcgctggag cggctgtccc tgctcctcct cgtgggtggg gccggcttcg agttcgccac
     5281 cggcgtcctc aacgtgcagt tgcactacgt ctttccgggt tccttctacg tactgcactt
     5341 ctacggggcg tgggtgttca tcggcgcgtt cgtcgtgcat gtcgtcttcc gcctcaggcg
     5401 ggccgtgatc gcggtggtga agggtccgcg cgcggaagag cagcaccggg cgcggccgct
     5461 cgccacggcc gggccgagcc tcgttgcgcc ccgcccggcc gagccgacga tgtcgcgtcg
     5521 cggcgccgtg ctgctggtgg gcgcggggtc ggcggccctg ctcgtggtga cgatgggcca
     5581 gagcatcggc ggctggatgc gcaggaccgc gctgctcgct ccgcacggcc aggacccggg
     5641 ttccgggccg aacgggttcc agatcaacaa gaccgccgcc tcggtgggtg tccggcccag
     5701 cgacatcggc cccgcctggc gcctgaccgt ccgggccggc ggtcggcaga ccgtactgac
     5761 ccgggacgag ctgtatgccc tgccgaggcg gacggtcgag ctccccatcg cctgtgtgga
     5821 gggctggtcc acgcccgacc agcggtgggg cggcgtacgc ctcgtcgatc tcgcggcact
     5881 ggtgggcgtg acccacgacg tgccgcgggt cctggtcgag tcggtgcagc gtggcggttc
     5941 cttcggctcg gtggtcctgg ccgccaacca ggtacgcgac acccgctcgc tcctcgcggt
     6001 ggaggtcaac ggggctgacc tctccccgga tcacggttac cccgcgcgga tcgtggttcc
     6061 gaacgccccc ggggtccacc acaccaagtg ggtcacgcgc ctcaccttcg gagagccgac
     6121 gtgaaccgct tccgcagccg ctacggagcc tccccgctgc atctgacggc ggtcctgtgc
     6181 tccttcgcgc tcgccctcta cgcgggggtg cgcctgctgc gcggcgacac actgggagtc
     6241 gtcctctggt tcgtcggcgc ggcgctgctg cacgacctgg tgcttcttcc gctctacgcg
     6301 acggccgacc gcgccctgca acgcctcatg accgcaacgg gccgaagcgg tacgcacccg
     6361 gtgggggacc gcgtggtggg cgtcaaccac gtccgggtcc cggcgttcgt ctccggggtg
     6421 ctgcttctgg tgtggtggcc gctcattctc gggcaggtcg acggcttcac cgccgccacc
     6481 gcgctgccga gcgatgtctt cctcggccgc tggctgctgc tgacggcggc gctcttcgcg
     6541 gtgtccgcgc tgtgtgcgtc ggcgcggctg tggcggcggt cgtcgcgcga gcggcggcgc
     6601 cgggacgcga ccgggtgagc ttccggtcgg cggtcaggtg ctgagcaggc ggttgaagaa
     6661 cgagcggtac tgctgaaggg cgacgcgcag gtcctcggtc ggcacctcct cgccgcgatg
     6721 ccactggccc tccagatcgc gcttgtgggc cgagaacgtc gtggcgaggg cctgcatcgt
     6781 ctcggcgacc aactggtcgg cggcgttgac ggaatcctgg ggatcgtcga cgaaccggct
     6841 ctggatctgc tgccacctgg cccggaactc ctcctgctcc gagccgagca gcggttcgtc
     6901 gtcctccgca ggttccgcct ccgcccgcgc gtgcccgggt gcccggtcgc cggcgtcctc
     6961 ctgccggtcc tcgcggccgg ccgtggcctc tccggggtac gtcggtgctc caccggccgg
     7021 ccccggtgcc tcggcctcgg tgtcctgctg cctgccggcg gcgagatcct ccgtggacag
     7081 cgggccctcg tcgggtcggg gtgtctcctc gtagcgcatc tcttcacttc cgtccgtcac
     7141 gcgtcgtggt ccgcgacgcg tgggcccttc cggcgcccac ccgcggcggt cgtgcactca
     7201 tgccgtgctc ctgcccggcc ggtccccgtt gtggagcagc tcctcgaaca gcgcgcggta
     7261 gtgcaccatc gcgccccgca actcctcggt ggtcgcctgg tggcggccgc tgcgatcgtt
     7321 gatgtcatgg gccgcgcgat agtgctccag ggtctccccg tgctcgaccg acaggtcctt
     7381 gagctgctgc tcgtaccctt cggtggggta gccccgctcg ctcatgagcg tggtcacgag
     7441 ccggtccgcg tcgtggacgg cgtcgtcggg ccggtcgacg aactgctcct gcacccgggc
     7501 ccagtcctgg gagtagcgct cgcgtgcggc ggcgggcagc ggcttgatgt ccagcgcgtc
     7561 atggcgctcc tggcgctcac gcagctcctg ctcacccgcc cggcggctgt cctgctcgtc
     7621 cacggtgcgc tcgtactccg ggccgaaccg ctcctgaagc ctgcggcgcc ggaccgtggc
     7681 caggcgcgct gccaccgcac acgcgatgag caccaccacg acggcgatga cgatgatgac
     7741 gacggtgagg gacatcgagt cctccggtcg ttggccgggc ccgtacacgg cccggtgagg
     7801 gcattggccc gccgcgtgag ctgccgcgcc cggcagggag gggccgcacc cgccggcgga
     7861 cggtcccgct gtccctgtgc ggacgaaggt gggtgcgacc acggcagtcg tcgttccgcg
     7921 cgactgcgat ggctgtgcgg caatgacctc cggcaatgcg gaggtgctgc ctccgttccg
     7981 tctccatcgt gctccctgtc gcccccggcg acaaggaccg gccccgcccg ggggccggct
     8041 cagaccggct cgggctgtcg ttccggcagc agcgccgggg cggtgtccgg gctcgtccag
     8101 ggtctggtgg tgcgcaggta gccgaggatg acggagccca tcgccaggag gacgagcggc
     8161 ccgaacagcc agggacgggc ggccatgtgc accgggagcc agcggtacga caccaggagc
     8221 agggtgaaga ccgccgtgcc atgggcgacc agccgcagtc ccgagcggtc ccagccgcgg
     8281 tcgaacgtgc gcatggccgc ctcgacggtg agtgagaaca cgaccccggc gaccaggtcc
     8341 acaccgtagt ggtagccgaa gcccagcgtg gcggcgagcg tggcgatcag ccagaacgtg
     8401 cccgcgtagc gcaggagtcg gggtcccgtg cgggtgtgga tgaagatcgc ggtggcccag
     8461 gcggtgtgca gactgggcat gcagttgcgc ggggtgatgc cgtcgtacgg caccgggtgc
     8521 gggatcgtga tcggcggcgg cgtgtgcggc cacaggttgg ccaccgacca ctccacgccg
     8581 ccggtgccgg acgcgccggg cccgtacgcg aagaccggcc cgaccaccgg gaagatcatg
     8641 tagatggcag gtccgaggag accgatcagc aggaaggtgc gcaccaggtg gtggcgcggg
     8701 aagcggcgct cggccgccac cttgcgcagc tggtacaggg cgaccacgat cgcggccacc
     8761 gcgagctggg cgtagatgag gccgaggagg ttggagcctg ccgggccgat ggcgtcgagc
     8821 gcacggcccg ccagccatga cgggttgccc agcgcgtgat ccgccgtcgc cacgtacggg
     8881 tcgagcacgg tggggcgggt cttcgaggtg atgagcagcc agctgtcacc gatcttgcgg
     8941 ccggtcacca ggagcagccc gaggccgacg cccttcagga gcagcacccg ttcggtgccg
     9001 gtgcggcgcg tgatcgcgaa gaccgcacag cccagcatcg cccacagcgc gccgttgccg
     9061 aagaggtgcc cctcgggcac ccggacgccg cacgcccacc ggccgagcac gaagacggca
     9121 tcgacaccga tcgccacacc ggcagcgacg aaccgttgtc gccaggtgag caccaccatc
     9181 atcagcgcga gaccgccgta cagcggtccg ggcttcggcg cgaacaacac ctcgcgcacc
     9241 tgggtgctga gcggcccccg ctcgccgtag tggcgcgcgg tgatctccag gccgatgagg
     9301 aacgcgaggg ccaccacgcc caccgccgtc cacagcatca cgcgcggccg gcgccacggg
     9361 gcggactcga tgacgtggcg tattcgtgcg cttctcggtg aaagtccagg tatcaattgt
     9421 tctgccgatg tgttggttgc cggagggcag gctggggcgg gcgcatgtcg agcatcgatc
     9481 atgccaccgc ccgattcggg tgccttcgcg gggatcggat ccgccccgcc gcctgcccgg
     9541 acgacgggtg tgccgcgcat ctcggacccc gtgactttgg ctggattccg catctgacgg
     9601 gtgttcggac atggccatac tcagggctgg gcgatccgtc ccgatccctc tgtccggagg
     9661 ccgctgatgc cgcagaccag tgttcctgca agtgccgtgc tcaacgcctg gctctcaggt
     9721 gccgaaagcg cgtacggcca gctcaacccg gccggtccgc tctatgtcgg cggcgctgcc
     9781 gccgaggccg cgctcaccga ctccagtgac tccctctacg gcttctgctc cagcccgagc
     9841 gggtcgcacg ggagctggtg ttgctgagcg tgcacgacac ccggcgggcc cttcgtggag
     9901 cgacttcccg cgaggggccc gccgcctgac cgaccgcccg cctcgcgggc ccttcaggcg
     9961 cctcgcgggg cgcgaactcg tggtgggacg gggacggttg atggcgaacg cggtggtgcc
    10021 gggagcaccg gaggagacgg agcacttcgc tcggcccgta cggagcatcg cccgcccctg
    10081 gcgggatcaa ctggcctgcg ccctggccga gttgccctcc ctggacgcga cggaacgcga
    10141 cgtgatcctt gaggccggtc acacggccct gctccggtcg ctgcacgcga agctgtcccg
    10201 cctgttcctg atcgaactgc acgcgctgcg gctctccggc ccggccgccg gggccggtgt
    10261 cgcccctggt cccggctccg cctccggtag cgagtcgggc cgagcgatct gggacgcctt
    10321 cgtcgagcag gccggcgcgg agggctacct cgacgggctg agcgaccggt acccgaacct
    10381 cgcccggcgg atcgccacgg tggcacggct ctcggtcacg gccacggcgg agttcgccga
    10441 gcgcctcgcg gcggaccggg atctcctcgc gccgctcctc ggcgcacccg cgggccgggt
    10501 acgggccgtc gcgttcgggg ccggagactc gcaccacggc gggctgaccg tcagccgggt
    10561 cgacttcgcc gggggcaccg tgatgtacaa gccccgcccg tccgaggccg acgtggcgct
    10621 gggtgcgctc ctggacgacc tgttcaccgg cctccccggc gcgccggcgc cggaccggcg
    10681 catccgcgtc cccgcgactc tggctcgcga cgggtacggc tgggccgagt tcatcggcca
    10741 ccggtactgc gccgacgggg ccgaactcgc cgtgttctac cgcaatctcg ggcactggct
    10801 cgccgtcctc cggttcaccg gcggcaccga catgcacgcc gagaacatga tcgccgccgg
    10861 gcccgtgccg gtgatcgtgg acgccgagac gctcttcgac gccccggccc ccttcccgcc
    10921 cagcggccgc ggcgacgcgg tggacgtggc ggcggcagcc atccgccgca ccgtgctgcg
    10981 caccgggctg ctgcccgtgc gcggcaccgg cttcgcactc ggcggagtcg acatctccgg
    11041 catcggcgcg ctgcccgggc agcagccact gatcccgcac ccggtgatcg ccgacggggg
    11101 caccgccacg gcccgcttcg aggtggacct ggtggccatg cccgtagcgg gcaaccaccc
    11161 cgccgccact ccggtcctga gcacctactg ggaccgggtc ctggccggat tccgcgagat
    11221 gaccgcacac ctcaggcggc ccggcctcga cccgcaccgg cttctcgccc gcttcgaagg
    11281 agcccgggcc cggcgcatcc tgcggcccac ccaggcgtac gtcgacatcg gccgcatgct
    11341 gtggcacccg gcctcgctgc acgacgaggc ggcggcggtc gagcgcgccc gggacattct
    11401 gcgccgcaac gccgacgcgc tgcccggcgc gccgaccgac cgcgcgacga tcgacggcga
    11461 gatcgccgat ctgctggtgg gcgacgtgcc gatgttcaac ttcaccgtcg acgccgcggc
    11521 cgtgcgcgcc accgtggagg actggcgcga cgccgacctg gccttcgagg agtcggtgat
    11581 ccaggacgcg ctcgtcggcg cgtatctgaa cgagcgctcg ctgccggccc gggtgcagga
    11641 ggccgcccac gccccgcacg cccgtgaccg ggagcggcgc cgccgtgaac tggccgcgca
    11701 gatggtccgg cggctgtgcg acggcgcggt gcgcggcgag gacggcacgg tcacctggat
    11761 cagccccgtc ttcaccccgg ccggctggtc gatccgggtg ctgcccgccg acctctacac
    11821 cggccagggc ggagtggcgc tcacactggc cgagtacgcc tgcgaggttc gagccgggcg
    11881 ggcggacgaa gtgccgggcg tgcccgagac gttcgagggc gcgctgcgcg tactgatcag
    11941 caccgaggac cgtacgccga cgccgtcggc cggggccttc agcggcgcgg cgtcacaggt
    12001 gtggacatgg ctcgcgctgc accgggtgct cggcgaggac tggatgctgg agcgggccgc
    12061 cgagcgcgcc ctgctgctca ccggcggacc actggtcgac gaggacgtcg aagtggacct
    12121 cctcaacggc gttgccggag cggtcgtccc gctgctcgac ctcgccacgg cgaccgggca
    12181 ggcacgctgg ctggacgccg cggcgcacat cggccaccgg ctgggcaagc tggccgtgtc
    12241 cgacgccgga ggagcccgct ggccgacccg cctcaacccc gagggcatcg gcggcttcgc
    12301 ccacggcgcc accggcatcg gctgggcact gacccggctc gcgctctcgg aggcgggctc
    12361 cgcggccgag cgcgatgact ggaaacgcct cgccgcgcgt gccttcgcct tccaggagtc
    12421 cctctaccgc ccggccgacg gcaactggct cgacgtgcgc gtcggcgcgg aggaggactt
    12481 cttcaccagc tggtgccacg gcagcgcggg catcggcatc ggcatgctgg acctccaccg
    12541 ccgcaccggc gaccccgctc atctcgacat ggcccggcgg gccgcggggg cctgcgccgc
    12601 ggagggcttc ggatggagcc acaccctgtg ccacggagac ctgggtctct gggagttcct
    12661 cacttccatc ggatcgggcg atgccaggga cctcgatgcc gagatcctca gcgggctcga
    12721 acagcgcggc ccggtcggcg gcctcgcgcg tgaggcgttc tcgcccagcc tcatgtccgg
    12781 cctggccgga gtcgtccaca ccctgctgcg gatgcacccc gacgccgacc tgcccaaccc
    12841 gctgctgctc gactgaaaca gggccggggg cccgaccggc cgtcgaccgt caggaccgcc
    12901 ggtcctcggg ttccggcagc cgcagcgcct gctgggtccg gctgcggacc cggcgcagga
    12961 ggtgccaccg ccgccgctgt tcccgcgaca gccggtccag ctcctcgacc aggcgctggg
    13021 accgcttctc cacgtcgagt tcgtcgagga tccggtccac ctcggcgagc agcgccccgt
    13081 gcagctgcca ctgcctcggg tggcgctgca cctcggcgag cagcaggtcg gcgacccggt
    13141 cgcggctggc acggccggcc gtcaactcgt ccgtcagccg ttgctccgcc tcctcggcat
    13201 tggtgctgac ctgcgtggtg atgaggaccg cgaagctctc gatggcccgg gcgagatgct
    13261 cgaagacgtc ccgcagtgcg agccccacct ccgggtcgaa gaggtgctcc tccgtccgct
    13321 ccttcgccag gtccgtgagc gaccggcaca ccactcgcag caccaccgcc gagatctcca
    13381 gggtgtcgag gccggtgcgc agcaccacgc gggacagcag cccctccttg actcgcgggt
    13441 tcagcctgag gctgtcctcg gcctgccgca gggaagcgtc cacctgggcg atgtcgtggt
    13501 cgagccgccg tgcctcgtga aggcgggcgg cggcttgcgc caccggagtg tggccgccga
    13561 cctcgtcccc gaggtccacc aacagccgcc gcatccgcgc ggcgagctcc tcgatggcac
    13621 cgcccgcgga atccacccac accgggggcg cgagcaacac gttgaacaac atgccgacgc
    13681 ccgcgccgat cagggtttcc agcacgcggt cccaggcggt ggccgagacc cgggtgacac
    13741 cgaggacgag catcgcgctg atggccacct cgggcacgaa ctccccgacc ttgacgaacc
    13801 gtccgaccac cagggccgcc aggatgatga gtcccaggct ccaccaggtg aggcccacga
    13861 gggagctgaa cccgacggcg agcagcaccc cgaccacgac ggagttcacc ctgcgcacgg
    13921 cagtcaccaa ggtggtgtag agggtgacct gcacgacgag cagggcggtc agcggggcgg
    13981 tgaggggcgc gggctcgctg ctcaggtgca gggccacgac gtaggagatg accgcggcgg
    14041 cggtggaacg cagggtctgc accaccgcgg gctcacggcg gcggcgagcg aaatcgaaca
    14101 gaggatcagt gaactcccac acctcccacc ccttccccct ctgtgacgtt cacacgcagc
    14161 cgcgtacggc acctggccgc ccccgccccc ctgcgcctgg tggaccgggc atccggccgc
    14221 cccctgcgcc tggtgggcgg ctgcgcgaaa acccgggtgc ggcggttcgg cgggctctgg
    14281 gaacatgccc ggatggtcca cgctctcgaa cccctggtcg tccggcacac ccaccgtctg
    14341 cccgccccgc gcggagccgc cggacaaggc ggggtcgccg cgcggcagtt cgacgcggcg
    14401 ctgatgtccg tgggcttcaa gctgtcggcg gagctgctcg gacacctgtc ggcgctgtcg
    14461 gaggggacgg tcgtcgacac ggcggtacgc accctggaca cactccgtgc gatggtcggg
    14521 gaccacgtcc ggcacaacgc ctacttcatt gacttcccgg cccatgtgcc ggacacctac
    14581 gccttctggc agcagtgcgt cgccgacgcg gtcgacaggg gtgtcgcggt cgcagggctc
    14641 agcgacggcg tggtcgatct gctgaccctc cccgcctacg gcacgtacca gcacagctac
    14701 gccgaaatgc tcgcagcgca cggggagttg ctcgcggcct cgggcgaccg tctgacggtg
    14761 cttcacctgg gtgaagcccc ggacgacgag atcaccgccc tgtatctggc cctcgcgggg
    14821 agcgccgcac cgctgggtga cgggggcctg cccgacctgg aggtgctcgc cgggcactgt
    14881 gtgcacgggc cccagccgga ggcgatcccg gtgcgggaga accgagccgt cgtgaaccgt
    14941 gcccgcgtcg aggccggagc ggatccgctg ctcgacacgg tcaccgatgt gctccggctc
    15001 gcctgtggcc tgtcggacgg cgatgtcacg ctggtgcagc cgacccggtt ccgctcgccg
    15061 tcccgacggg ttcgtcgagt gctgctcgcg ggactcgacg ccgtggtcgc ggcgaacccg
    15121 gccaagctcg ccgacgtatc cgcgcatcgc gaggcgttca agcgcctggg ggagcggctg
    15181 cacgcacacg agtacgcggc ccgctggccg cacgccgccg atgtgttcgc ggtggcccgg
    15241 ggcgagaagc gggcccggtc cttcgacagc cgggtcgagg aactgctcgc ggccgatgat
    15301 gtcctgggcg cggcacggct gttggagtcg gctccgggca agctcttccg ctgcctcgac
    15361 cggctgctgc gtgcctgcgc cacggacgcc gaacgcgacg cggtggcccg ggcggccgcg
    15421 cggctggccc cggaggtgtc gggccgggtc ctcctgtcgg tgcgcgagca cttccacaac
    15481 cgggcgcggg gaagcggtgc gcgccgcgtc ttcgtcaacc gcctcggccg cgcctgggcc
    15541 gccgacgagt cgcgctcccc gctgcccgag gcggtgcggg cccgcctggt ggccgcactc
    15601 gacgcggaga cgagccgccg actgcccgcg ccggggcacc tgttgatcga tccggacgtc
    15661 ctcgacgtgg cgctcccgct cagcggcagg gcgacggcgc ccgggttcgg tgtgctgccg
    15721 cgcggctccc tctcgccggt cgacggcgaa ctgctgcggt tcttcgtgta ctggaagcag
    15781 acgagcgaca ccaccgactt cgacctctcg gccctgatgc tcaactccgt ttacgagacc
    15841 gtctcctggc tctcctacac ggctctcacc gaggtcgagg gcgagcactc cggcgacatc
    15901 accgaggcac ccgacggggc gtcggaattc atcaacctgc gcctgggggc cgtgcgcggg
    15961 acctacatcg ttccgcaggt caacatcttc tcgggggagg gcttcgagga ggtcgaggag
    16021 tcgttcttcg gcttcatgct gcgcgagggc gaccagcggg gtcgcccctt cgagccgcgt
    16081 accgtacgca tgaagtcgca gttgcgcggt ccggggcgcg tcgcgctgcc gctggccttc
    16141 atacgcgggg aggacggacg ctggcgcgcg aagtggctcc acgtgtacct caagggaacc
    16201 ccgagcgcga accgggtcga ggggaacagg gtgtcggtcg cggccctggt ccggggcttc
    16261 gtcgagcgcg accacctcac ggtgcgccac ctcaccggcc tgatggccga ccggggagac
    16321 gtcaccacgc tgtgggacgg caagacggtc ccgcagggcc ccgtgacgta catcggactg
    16381 gagcgaccgg acggactgca tcccgactcg tgcgtcatca ccccggaaaa cctgggcgac
    16441 ttggtcccgg agtgactgct acggttgagt ccggcgaggc catgaaggga cttccttctc
    16501 acactcctga aactagtccc ttcgctttcc tcgccctcga cgtgacgccg ggatctgccg
    16561 cacggcaccc cggcgttcgt cgttcgcgcg tcacccgctg ggggcctcgg cggcgtcgtg
    16621 gtgccgccat gccccgggac gtacggtgac gtgatggtgc gcgtgcggaa gatgaacgga
    16681 accgatgtcg aagccgtctc ggcgatacgc gtgcggggct ggcagtccgc gtacgccggc
    16741 atcctgccgc ggtcgtatct ggaggccatg acggtcgagg acgacgccgc ccggcggcgg
    16801 gagtggttct cgctgccgca ccggcagtcg gtcgacctcg tcgccgtcga cgggggcgaa
    16861 ccggtggggt ggatcaacta cgggccgtcc cggagcgagg tgcccgaggt tcccgacgag
    16921 cgcacggggg agatcaacgc gctgtacgtg cgtcccggcc tgaccggccg ggggatcggc
    16981 cgagggctgc tcgacgaggc acacgcgctc atgcagagcc aggagttccg ggccgttctg
    17041 ctgtgggtgc tcgcggacaa ccagggcgcc cggcgtttct acgagcgggc cgggtaccgg
    17101 gccgacgggc acacccaggc cgacgtgtac gacggtgtcg ccgtgcccga actccgatac
    17161 cggcgcgcgt gctggagcgg gccgcggacc ggtgtggccg acagcactgt cggccacacc
    17221 gacgcgagcg gcagcgcccg ctagcagcgg ttagaacccg ttgaggcggt ggtggaagcc
    17281 acggccgggg tacctgccct cccactggga gtgcatgcag ccggagcccc aggcagcgtg
    17341 cccaccgccc gcgccggcga acgagccaca ggcgctggtc tcgccgccgg agtggtggtc
    17401 gtcccggtcg tgggccaggg cggtgccggt gctgccgagg accgcggcga tggcgagagc
    17461 gccggcggcg agggtggtgc gcatacgcat gtctgctcct gtcggggtgt tcgggtgggg
    17521 aaacagggtg atcagtcccc ggtgccctca ggtcgcgaaa cctgtgtcac ccgaccgccg
    17581 ccacgacggg ccacgggcct gcaccggccg tatcgcatgg tcgccgcggg cgctaatcgg
    17641 ggtggaccgg caccacgcag ttgtcgtcgt gacccggcgc gtgcccggtc ggccaggcca
    17701 cgccctcgaa caccagcttg tgcgagccgg gatcgaggcg caccaccgac agcgccttgt
    17761 tgtacgggtt tcccgcgttc gtgaggcaga tccagccacc ggcgccccgc acgcgcaggt
    17821 cggagttcag cttcccgagg tccctgacca cacggtcggc cgtcggtacc tcgagaccgc
    17881 tggtgtgcac cgcgcgcgcc agcgcccggc tcgccgtgag gacgacgtcg tacgtgacga
    17941 tcgtccgccc gtcgtcgagg ttcaccgggc cgatgggccc cggctggtcc gcgatgccac
    18001 ggcgcagcgc gttcatcgag tcctgcgcct cccgcaggta cagcggaggg tcctgcccct
    18061 tcgtcctcgg gtcgttctgc cacttggcga gctcggtgct ccaggcgtcg gggtgcgccg
    18121 gtgcggcgta gcggatgctg acggacggct tgcccgagcc cgggtcgccc cgcagcaggg
    18181 cccggtcgtg gtcgtccagg cgctcgtcga gcgtggtggc gtcggacccg gtgatcacgg
    18241 tgtacgacgc cttctcgcgg cagtaggtgg tggcgagctt ctccacgaag agcttcaggt
    18301 ggaaggcccg tccggcgaag tagatgacgt gggtgttgga gcggcagatg tttcccgcga
    18361 agtcctcgaa ctcgttcggg gtgactcctg cttcctcgac gccgggcgac tcgaagcgca
    18421 tgtcctggac cccgcgtccg ccttcgttcc gcctggcctc ggcgaacgcg tcgcgcaggg
    18481 agcggtcgta gtcgtcaccc ggccggtcgt ccgccaccaa cgcggtctcg gagccagcca
    18541 gttcggggtc gaacgccagc agcgcccggg cctgctcgcg agaggtggac acgactcggg
    18601 cgaggccggg gtacgggacc gtgtcggtgc cctcggggtt ggcgaagtcg tccgccgtca
    18661 cgacgctggc caccgcgggc aggtgcaggg tgttggtcac gtacgtgagg gcctccttgg
    18721 tcttgtccag gctcagattg aagcccatca cgaccctcaa gtccggctcc tgagaggtga
    18781 gttgatcgag cgtgccgcgc cagcgcccgt acccgtcgcc cgggttggcg aggaccagcc
    18841 ggatcgcggg cttcaccgag tccgcgccgt tcgccgccac ctgcgcgagg tacgcgccct
    18901 gcacctcgct gaggatctgc cgctgcacgg cgggactggc ggactgcatc gggatcagca
    18961 gggctacggt cgcgtgcttg cggcccgcga ccgccttgtt ctgctcggcg atgcgctcga
    19021 agacctgggg catgcccttg acgtcgggca tgaacacgcc ggtcccgtcg gagacgccca
    19081 cgcactcgcc tccatggatc tcgagtcccc ttccgcaggc ggccggttcg cggaagaagg
    19141 tgacatagcc gccgagtccc gcggcgatga gcgcgactgc cgtgaccccc acggtcaccg
    19201 ggcccaggag gcgcacgccc ggtgcgggac gcgggccggc ggcatcgtcc agcacgattt
    19261 ggacgagcag gctgggcagc ggttcgctcc cgccgcccgc ccgcgatgcg cccacctccc
    19321 ggcgctcacg gaaacgcccc gggatctcct cgccgaggca gtccgccggc acggcgggcc
    19381 ggccgcccgt cagcgggtcc gcctcgcccg gccgggacgt ggtgatgacc acggggtgca
    19441 cccgcaggtc cttggccgtg ccgctgagcg cttcgagcat cctgtcccgg atgatccgcc
    19501 gtgcggggat cgtgtccacg tccggcagga ggatgacggg acggcggacc cggttgaggc
    19561 ggcggagcac gccgtagtgc gcgtccacgt cggcgagcag cgcctcgacg agcagccgct
    19621 gcttctcgtg tgcgggcctg gcgctccagc cgtccagttc ctcgcagacc gcttcgaacg
    19681 tgcgcaggcc cgggaacctc cgcttgcgga accagcgcac cgtgcggtag cacggcagcc
    19741 tcagggcgtt ggcgatcttc agcaacaggc cgaggaatcc cccgagttgc tgggtgacgt
    19801 acggatcctg aatcagcggg tcgagccggg tgcgggcctg cggcatggag tgccgtcgct
    19861 cctgcgcgat cgcttcctcg atctgccgct tcagggctcc catccgccgg gcgtgggaat
    19921 ggtcgcccgt ctgctgccgg tcgtacagcg cggcgcgggc ggccgcgaag cgcgggaaga
    19981 cgatcggcag gccgcgagcc acgatgccgc cgtagccgca gccctcggcg accgcctgca
    20041 actgctcaag gacctgtcgc tcggggtcgc tctcctcgac gtcgctcgga ttgttcaccg
    20101 gaacgatgcc gcgatactcc ttgagcagcc gggtgagcca ctgccgtacg gggtcgctcc
    20161 cgccctcgat ctgcaacacc agcgccccgg cgtcccgttc gaagcgcacc ctcttgcggg
    20221 agaacctctc cctgaacgtg agttgcgcga tgaccgcgtc cagttgcacc cttgctcccc
    20281 gttgccgtgg ccctggcgta ggcggcgcgc ccggcggcgg ccgtagccgt tctcggccga
    20341 cgtcgaatcg gtgagcactc taggtgtcaa ctgcccttga tctggggcga gttgctcatt
    20401 caccatccat gtgttcaaga acggtcggat ctggacaggt ggtgcgcatc gcgcacactc
    20461 ccttcgacct aaccgccgcc gaccgcctcg ggacgggccg gcgtgggcgg ctggaagcag
    20521 gcggtgacgc tcttgccccg ggggcaggga taggcgtacc agtcgtcggc gaggacgtcg
    20581 atcaggagca ggccgcgccc tcccagggca tcggcttcgg ggtcgcgctg ttcgggcagc
    20641 tggggtgagg cgtcgtgcac ggtgacgtgc aggcactcct cgtcccaggt gaggatgagc
    20701 tgcgccgtgc tgcgggcgtg gacttgggcg ttcgtgacca gctcggacac ggtgagcagc
    20761 accgagtcga cgacgtcggg cgacgtccgc gcccagtcga gcgtcgccag atgctcgcgc
    20821 gtccagtccc tcgcctcctt cacgctgctg gtcagcggaa gggagcgcgc ccagcccacg
    20881 gccttcagtg atgagtcctt cgccacggtc tctccttggt tcgacggcgg ctcgacggcc
    20941 ggcttctcgt cccgtctgcc ccgaaaaccg cagtgtggtc agccccggac gctgcccggc
    21001 gcactccggg gccccgggac cgcgggctgt ctccagtcga gccggagcac ggcgacgtcg
    21061 tcggagtggc gtcccgcgtt cagcgccgag gtctccttga tgaggaggtc gatgtgtgcg
    21121 gcggggtccg actgcggcag ccggtcgatg agggtgagca ggccctcgac tccgaggcgg
    21181 ccccgggccg agccgttgcg cccctcggtc aggccgtcgg tgtacagggt cagcgctccg
    21241 gcggccggga gtgggatgag gctcgcgggc cagttgctca cccgggggtc gatgccgagg
    21301 gcgatgccgt gcgcggcggt gatctcgcgt gatccccggt ccgtggagag caggggcccg
    21361 tgatggccgg ccaggtgcag ctcggcggtg gccgcgccgt ggtcgagggt gaggagggca
    21421 caggtcgcga agagcggccg gtcgccgcgt tcggcgatca ggatgcgctc catcaggtgc
    21481 aggagctccc tgccgcggtg gccgccgagg atcagtgagc gccaggcgat ccgcaggcac
    21541 acgccgagcg cggcggcgtc gggtccgtgc ccgctgacgt cgccgacgac ggcgtgcagc
    21601 agcccgtcgt ccccttccac gacgtccagg aagtcgccgc cgagcagcgc gagttcggtg
    21661 cccggcagat agcgcgtggt cactgtcacg gccgacgtgg acaggagcgg ttgcggcagc
    21721 agccctcgct ccagccggga gttctcctcg gctcgcaggg tggccgcctg ggtctgggcg
    21781 ttcgcgagtt cggtctgact ccggtagacg gcgtaacgga ccgcccggtg cagcagatcc
    21841 gcgtccacct tgcccttgac caggtagtcc tgtgcgccgg cggccatggc gtcgctgccc
    21901 gcctgggcct cggacagccc ggtcaggacg atgacggcgg tgtgcggcgc ggccgcccgg
    21961 accgccgcga ccgccttcgt gccggagacg tcgggcaggt gcaggtcgag caggatgcag
    22021 tcggccgtgc gcagggccgg atcggtgcgg gcgccggcga ggctcgtgca cgtggtgagc
    22081 tcgaaccgca gcccggtgtc caggagcagt tcctccacca gaacggcgtc cgcaaggtcg
    22141 tcctcgatga ggacgacgcg gtaggtctgc tcctgcggtg ccgcgccggt cgggttcgtc
    22201 acgaaggagg tcatgacgcc ggcaccacct gagaggcgtc ggcgccgacg agttcacccg
    22261 gcccggggcg ttccgccggc tcgggggcga gggtgaacac gatgcgggtg ccgtgctcgt
    22321 gcgtgaggtc gacggcgatc gtcccgccgt ggaactcgac gatcttcttg cacatcgcga
    22381 gcccgatgcc gctgccgctg taggcgtcct tggtgtgcag ccgctggaag atgacgaaga
    22441 ccttgtcggc gtactcgggt gcgatgccga tgccgttgtc ggtgacggtg aaccgccaca
    22501 ggacgtcctc gcgcacggcc gatacatgga tgcgtggtgt ctgaccggcc cggcggaact
    22561 tgaccgcgtt gccgatcagg ttctgccaca gcatgcccat ctgggtggaa tcggcgatca
    22621 gggtcggcag cgggtcgtac gtgatctcgg ccccggtctc ctcgatgctg agactcagcg
    22681 aggacagggt gcgatcgagc gccctgccca ggtccaccgc ctgatggttg ttgtggaccc
    22741 ggcccacccg ggagaattcg agcagatcgt tgatcagggt ctgcatgcgg ttcgcgccgt
    22801 cgacggcgaa atcgatgtac tggtcggccc gttcgtcgag ctgtccgccg tagcgg
//
