LOCUS       NZ_CP070373            21032 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1467766
            Orig. end                         :: 1488798
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21032
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21032
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21032
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11032](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11032
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            520..954
                     /locus_tag="GWQ54_RS06705"
     CDS             520..954
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889332.1"
                     /locus_tag="GWQ54_RS06705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167157033.1"
                     /transl_table=11
                     /translation="MSTEQTPEAPAEPRPGRLTAAAALSALEGLALVAGGLFMLVMGLT
                     GKPDKPTQAEMGGLTLVVLGLIPLIAARGLLRRRSWSRGPAMITQIMALPVAWMFLNSD
                     GAPWIPAGIALAAAAITGLVLLVNPATTQALGIRGPMRDA"
     gene            complement(1012..1914)
                     /locus_tag="GWQ54_RS06710"
     CDS             complement(1012..1914)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458249.1"
                     /locus_tag="GWQ54_RS06710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_229893075.1"
                     /transl_table=11
                     /translation="MRPVGIPEQQARPHPVDSPVDGPDGVLYAAEQAERAALMSEHIEH
                     RHHDPHDRSGARAMFFELRKLPDGSSEKAELRNQLVRMHLPLVEHLARRFRNRGEPLDD
                     LTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLA
                     LTTATAELSQQHGRSPTVHELAERLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAV
                     ADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHV
                     SRLLARTLAQLRDKLLVEE"
     gene            complement(1959..2372)
                     /locus_tag="GWQ54_RS06715"
     CDS             complement(1959..2372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="GWQ54_RS06715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_161258184.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVESTVAEDRTVSISLYKQRGAGPGPA"
     gene            complement(2671..2931)
                     /locus_tag="GWQ54_RS06720"
     CDS             complement(2671..2931)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="GWQ54_RS06720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_161258187.1"
                     /transl_table=11
                     /translation="MSECPHVAELPRPEPAPLNDTCPECLKDGTHPVQLRLCLVCGHVG
                     CCDSSPHQHATGHFEETGHAVMRTFEPGESWRWCFVDGLLV"
     gene            2988..4586
                     /locus_tag="GWQ54_RS06725"
     CDS             2988..4586
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521043.1"
                     /locus_tag="GWQ54_RS06725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_161258189.1"
                     /transl_table=11
                     /translation="MDALPLVALIAASAAVAGAARRSPVPAPLLLVAVGLIGAYVPGVP
                     AYTLDPHIVLPLVLPPLLHTAALESSYLDLRANLRPVALLSVGYTLFATVAVGYLAYLL
                     VPDLPLTAALVLGAVIAPPDAVAATAIARRLRLPSRITTILQGESLVNDATAITAYKVA
                     LAAAVGAGATWGGGVKEFALASIGGVGVGLVLMLPIHWLRRHLHEALLQNTLSLLIPFV
                     AYAAAEQVGASGVLAVVVVALYLGHRSWQVDFATRLQEEAVWKMVSFLLESAVFALIGL
                     QMPVVLKGLGEYGVGEAVWYAIGVFVLVVAARFVWVFPATFLPRALSEKIRRREPETDW
                     TAPVIVGWAGMRGVVSLAIAFSIPLTMADGSAFPARNLVLFLTFTTVIGTLVVQGLTLP
                     PLIRLLKLPGRDTQAETLAEAQAQSEASRAAEARLDELLADPRSTLPPPLADRLRTVLE
                     RRRNAVWERLGAVNEVTGESADATYRRLSREMIEAERKVFVSLRDDRRIDDEMMRTLLR
                     RLDLEEAAAYRDPGT"
     gene            complement(4975..5856)
                     /locus_tag="GWQ54_RS06730"
     CDS             complement(4975..5856)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892047.1"
                     /locus_tag="GWQ54_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_205530634.1"
                     /sec_met_domain="PALP (E-value: 1.7e-16, bitscore: 59.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPEALAPRPPSPLEEVTDERFARHGVRLLLKRDDLIHPALVGNK
                     WRKLVPNLRAAAGRPVLTFGGAYSNHLRATAAAGRLLGFPTIGVVRGDELAGRPLNDSL
                     ARCAADGMRLHFVDRATYRRKSDPEVLAGLLDLLAPGAYVVPEGGSNSLAAQGCTELGA
                     ELRGSTDVAAVACGTGGTLAGLAAGLGPAQRAIGVPVLKGGFLAEEVDALQRAAFGGPR
                     GIWTLDDRFHFGGYARVPPELESFARDFEDRHGVGVERVYVAKVLFALHALTQEGSFTR
                     GTTLTAVITGRP"
     gene            complement(5886..6476)
                     /locus_tag="GWQ54_RS06735"
     CDS             complement(5886..6476)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437931.1"
                     /locus_tag="GWQ54_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidoglycan recognition family protein"
                     /protein_id="WP_161246045.1"
                     /transl_table=11
                     /translation="MAPPMSADQFLAALRAEGLRVVEVGQWRTHNRAGHGGWAPINGVV
                     IHHTATSGADATVRICYDGYDSLPGPLCHGVITKDGTVHLVGNGRANHAGAGDGNVLRA
                     VIAEKRLPQPLTNDTDGNTHFYGFECENLGDGKDPWPEAQLEAIEKAAAAVCRHYGWTE
                     RSVIGHKEWQVGKIDPRGFTMDWLRERVHERLK"
     gene            complement(6603..7793)
                     /locus_tag="GWQ54_RS06740"
     CDS             complement(6603..7793)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154134.1"
                     /locus_tag="GWQ54_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="globin domain-containing protein"
                     /protein_id="WP_167157030.1"
                     /transl_table=11
                     /translation="MLSEKSTVTVRATLPAVGAAVGTITERFYERLFADRPALLRDLFN
                     RGNQAAGLQKQALAGSIAAFATHLVNHPEDRPDVMLNRIAHKHASLGVTADQYEIVHRH
                     LFAAIAEVLGEAATAEVAEAWDEVYWLMANALIDIEARLYAEQGVLAGDVWREWTVAGR
                     TEETATCATFRLRPADGAPAPAFKPGQYVSVQVELPDGARQIRQYSLTSAPGGELRSIT
                     VKRVQGDPDGEVSGHLHAHLREGDGLRVSAPYGDLVLDADGSPLLLASAGIGCTPMVAM
                     LGQLAADGHRAPVTVVHADRSPAEHALRDDHAALTAQLPDATVHFWYEDPEPGHPADRT
                     GLVDLTRLPVAPGTRAYLCGPLPFMRAVRTQLLAKGVRAADVHYEVFGPDLWLAQD"
     misc_feature    7853..7867
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(7911..8354)
                     /locus_tag="GWQ54_RS06745"
     CDS             complement(7911..8354)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="GWQ54_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_161246041.1"
                     /transl_table=11
                     /translation="MRLTRFTDLALRVLMRLAVIENAADQVPPTTREVADAMRIPYTHT
                     AKVVARLQHLGLVEARRGRGGGLAVTAAGHLASVGGLVRELEGPGDVVECEGATPCPLA
                     AACRLRRALHRAQEAFYESLDELTVDDLVTAPTGPLLLGITSR"
     misc_feature    complement(8373..8389)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.28"
                     /tool="antismash"
     gene            8527..9924
                     /locus_tag="GWQ54_RS06750"
     CDS             8527..9924
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019520935.1"
                     /locus_tag="GWQ54_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_167157028.1"
                     /transl_table=11
                     /translation="MSVEAGPENRTQQSLGTAAARNLATTTKSAPQMQEITSRWLLRML
                     PWVQVQGGTYRVNRRLSYSVGDGRITFVQTGERVAVIPAELGELPALRDYEDEAALGEL
                     ANRCEQREYAAGEVIATAGDATDRVFLLAHGRVEKIGTGQYGDETELGFLADGAHFGED
                     ALVSGEAVWECTYRATTGCTVLVLSRADVLNLAERSESLHDHLASVTGLPEQRTNNYGE
                     AAIDLSAGHVGEAIIPHTYVDYEGSPREYELSVAQTVLKVHSRVADLYNQPMNQTEQQL
                     RLTVEALRERQEHELVNNREFGLLTNCDYEQRLQPHDGVPGPDDMDELLSRRRGSKLFL
                     AHPRAIAAFGRECNKRGLVPESVEVAGHHVPAWRGVPIFPCNKIPVSDARTTSIICMRT
                     GEAEQGVIGLQQSGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAILVPDALGVLEN
                     VEVSRWR"
     gene            10001..11032
                     /locus_tag="GWQ54_RS06755"
     CDS             10001..11032
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312071.1"
                     /locus_tag="GWQ54_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_161257802.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-60, bitscore:
                     203.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEAMEGREAGDLLERARTVVDPQLRASVASLPGSMRRVAMYHFG
                     WEHADGTPAGGQSGKAIRPALVLAAATALGGRPEAAVRAAAAVELVHNFTLLHDDVIDE
                     DATRRHRPTAWTVFGTPDAIIVGDALFALALRLIADDGHPASGAASARIAACVIELCAG
                     QQADCAFEQRGPQDVSLDECIAMAMAKTGALLGCACALGALYAGAGDEEVAAMDAFGRE
                     AGLAFQLIDDLIGIWGDPGRTGKPAGADLAAHKKSLPVVAALNSGTPAAAELAELYGGP
                     MGAEAVRRAADAVDRAGGRDWAQVHAADRMARAVDHLSRAVPDLTAAGELLALAEFVTR
                     RTR"
     gene            11180..12403
                     /locus_tag="GWQ54_RS06760"
     CDS             11180..12403
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073441.1"
                     /locus_tag="GWQ54_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_167157024.1"
                     /transl_table=11
                     /translation="MTSRLLPPAGPARGLATAQLVNSLGDGAFLVTSALYFSRVVGLPA
                     TRIGLGLTLAWAVGALAGVPLGQLADRRGPRTVAVLLAAATGASVASFLFVRGFLPFVL
                     AACCYATAQTGLSAARQALLSALVDRGDRTRVLAHLQSTLNAGLAVGAAFGGVALHYGT
                     RTAYLAVFALDAVAFLFCALALMRLPHVPPRPVVPGGGPRFAVLRDRPYAVITFLNTLL
                     LLRMPLISLAVPLWTVTRTDAPGWLVSALLVLNTGAVMLFQVRTASAVRDLPSARRTVA
                     RGGVLMLASCAAFALSAAGASPWAAVGVLLVAGALQVAGEMMQSAGAWQIGFDLAPADQ
                     QGQYQGFFGMGVPLARMLGPLLLTALVIDWGVPGWLLLGALFLGAGLALGPAVRWAERS
                     NSALVAAG"
     gene            12529..>12951
                     /locus_tag="GWQ54_RS06765"
                     /pseudo=""
     CDS             12529..>12951
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959109.1"
                     /locus_tag="GWQ54_RS06765"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF6304 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTPQSWAGWYRDRLGSEALTITTDGTQLRTRIRGVDFAGASFDSL
                     GPVPGIPAESGAFALDDGNLRDFVLEWDMPVPIASDDGAVQEATLSCLLSLKPPEPDLG
                     VALHFGGAVYASGRAEVDFGSVLADIRRQLPSGSSLQ"
     misc_feature    13113..13129
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.13"
                     /tool="antismash"
     gene            13146..14117
                     /locus_tag="GWQ54_RS06770"
     CDS             13146..14117
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_167157020.1"
                     /transl_table=11
                     /translation="MIRVRRLTAVAALPFLLALAVDLTLYVLLRDRLPDPLASHFTGKG
                     RSDGTQSRGSTPVFACVLHLGLGALWAGMAAVGDPAVRRLRWLIAAGYATAGFVGYLLA
                     ATLLANADATDPARVRLPLWQIAVGAGIAVLAAALGRLLLLAVPTPPPEPSSRPDADRT
                     PRLDLAEGEVAGWMRRAPSRVLLVCGTLLLVAAGALLFAVGPGNAVGAFFGAVVCLVFS
                     CPYVTIDRRGLTARPTALPWPRIRIPLSDVDRAVSRDIKVLAEYGGWGYRVRAGKSGLM
                     LRSGEAIVIRRSDGREFAVTVDDAGTAAALLNTLARRAEARD"
     gene            14117..14473
                     /locus_tag="GWQ54_RS06775"
     CDS             14117..14473
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981078.1"
                     /locus_tag="GWQ54_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_167157018.1"
                     /transl_table=11
                     /translation="MLFRVDPASPRPLGDQIAASVRGAIADGKVTPGERLPSARSLADL
                     LGVNVHTVLRGYQRLRDEGLIELRRGRGAVVVHDTRARGRAELMLKVRELVDQARELGL
                     TEDEVVGLVRRGLA"
     gene            complement(14514..14924)
                     /locus_tag="GWQ54_RS06780"
     CDS             complement(14514..14924)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523291.1"
                     /locus_tag="GWQ54_RS06780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glyoxalase/bleomycin resistance/extradiol
                     dioxygenase family protein"
                     /protein_id="WP_167157016.1"
                     /transl_table=11
                     /translation="MDPLEPPYPRLLVDPYEPAFRFYDAVLPDLTGCTLARGNSASGYA
                     SWDAPDGRTALALFTRSAMAAVLGEGRMPGGGASLVIHMATRDALDAAVSLCAKAGGPV
                     AVPVRDLPEWGPGMRAAHLLDPAGNLVELQTY"
     misc_feature    14961..14976
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            complement(15015..15542)
                     /gene="cpt"
                     /locus_tag="GWQ54_RS06785"
     CDS             complement(15015..15542)
                     /codon_start=1
                     /gene="cpt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115663.1"
                     /locus_tag="GWQ54_RS06785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chloramphenicol phosphotransferase CPT"
                     /protein_id="WP_167159530.1"
                     /transl_table=11
                     /translation="MIVLNGGSSSGKSGIVRCLQAVLPGAWLAFGVDSVDAAMPASLRG
                     EGGLEIGADGTVTVGPDYRRLSDAWARGVAAMVRAGARVVLDEIFLDGADAQKRWQQAL
                     DGLDVLWVGVRCAPDTAAGRETARGDRVPGMARGQAESVHVGVRYDIEVDSAGAESMAC
                     ARLIAERYARPA"
     gene            15641..16198
                     /locus_tag="GWQ54_RS06790"
     CDS             15641..16198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071615.1"
                     /locus_tag="GWQ54_RS06790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenylate kinase"
                     /protein_id="WP_167157014.1"
                     /transl_table=11
                     /translation="MRRILVVGSTGAGKSTLAHELGERLGVPYHELDALHFAGPGWARD
                     PHFAARVAEIAATPAWVLDSYGTPDVRPLLWERADTVVWLDYPRHVVMPRVLRRSLRRT
                     VLRERIFNGNRETLREWFRGDHPARWAWSQYAPRRAALTALTTDPALAPLHTLRFTAPR
                     EARRWLRTIGAGRGERRKGPAG"
     gene            complement(16272..16667)
                     /gene="sodN"
                     /locus_tag="GWQ54_RS06795"
     CDS             complement(16272..16667)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="GWQ54_RS06795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_053730656.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKFQAN
                     EDAHFRARAVVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKA
                     STDPATGQKALDLIAEIDRIFWETKKA"
     gene            16843..17268
                     /gene="sodX"
                     /locus_tag="GWQ54_RS06800"
     CDS             16843..17268
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845506.1"
                     /locus_tag="GWQ54_RS06800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_167157012.1"
                     /transl_table=11
                     /translation="MTDEGREPRVPLGIAEVLGTSMVPTLLHGDQLLVHYGAELRIGDV
                     AVLRHPLQQDLLIVKRLMELRESGWWVLGDNTDDEVVDSRAFGAVPVDLVLGRVRGRYR
                     PMAAGRRRTVGYLASWAVSSVRPVLSDRSVSRRLRAR"
     gene            complement(17187..17801)
                     /locus_tag="GWQ54_RS06805"
     CDS             complement(17187..17801)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312054.1"
                     /locus_tag="GWQ54_RS06805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_167157010.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARSKDALTSVEAVRDLFGGNQSAARR
                     ATDADVTRFRSVRARLRAVFEAADRGEEVQAVDLLNSLLLEFPVSPQVSGHEHRDDDGR
                     PLWHMHLADHPSNATAGYAAIASMGLAFHLTEYGVDRLGLCQAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLETERSDSTGLTEETAQDAR"
     misc_feature    17794..17809
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    17857..17872
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: medium, score: 26.18"
                     /tool="antismash"
     misc_feature    complement(17857..17873)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 24.89"
                     /tool="antismash"
     gene            17987..18676
                     /locus_tag="GWQ54_RS06810"
     CDS             17987..18676
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312053.1"
                     /locus_tag="GWQ54_RS06810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_167159528.1"
                     /transl_table=11
                     /translation="MPDREERFRVMLDMVEACVGPAPRVLDLACGTGSITDRLLRRFPD
                     AVSTGVDLDPALLAIAEGTFAGDERVTFVAADLKDPHWVQSLPYDSYDAVLTATALHWL
                     HAEPLAALYGQVAGLVRDGGVFMNADHMIDPATPRINAAERAHRHAGMDRAKAGGALDW
                     AQWWALAAADPALAGPTAKRYEIYGEHADGDMPAAGWHAETLRAAGFAEARPVWASPSD
                     TLLLALK"
     gene            complement(18735..19502)
                     /locus_tag="GWQ54_RS06815"
     CDS             complement(18735..19502)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="GWQ54_RS06815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_167157008.1"
                     /transl_table=11
                     /translation="MTAQPMVKAEGVHKSFGPAHILKGIDLEVAEGEVFCLIGPSGSGK
                     STFLRCINHLEQINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLF
                     PHMTAVENVMEAPVQVKRESKAVARERALKLLDRVGLADKAGNYPSQLSGGQQQRVAIA
                     RALAMDPKLMLFDEPTSALDPELVGDVLDVMRGLAEDGMTMIVVTHEMGFAREVGDSLV
                     FMDDGVVVEAGHPRDVLTNPQHDRTKSFLSKVL"
     gene            complement(19507..20439)
                     /locus_tag="GWQ54_RS06820"
     CDS             complement(19507..20439)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036134.1"
                     /locus_tag="GWQ54_RS06820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_167157006.1"
                     /transl_table=11
                     /translation="MTDKLDKTPGPADAAPEQVPPDIIRAIPVRHYGRWVSAVVVVAVL
                     GALVYAFAQGNVRWATVTDKLFDGSILTGLWHTILISVVSMAVGLILGVLFAVMRLSKN
                     PVTSSVAWLYIWFFRGTPVYVQLLIWFNLALIFPILNLGFYKDYMTAVMTPFLAALLGL
                     GLNEGAYMAEIVRAGIQSVDEGQTEASHALGMTQMQTMRRVVLPQSMRVIIPPTGNEFI
                     NMLKTSSLVVAVQYQDLLRSAQDVAATSFAVMEMLFVASIWYLALTSVFSVGQYYLERR
                     FARGSLRSLPPTPLQRIKSNLLSLSHWRR"
     misc_feature    20712..20726
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.83"
                     /tool="antismash"
ORIGIN
        1 ccctcgtcga tgctgccggc caccccggag gcgagcccca ggctcaccgt gcggctgcgg
       61 ttctcgcgca gcgcgtcgag aatgacaccg gtcgactcca cagcgtcatt gggcagaccg
      121 agcgcccgcg cgaacacatt cgtcgaaccg ccgggaacta cggcgaattc ggggagttcg
      181 gggctcggcc cgttgtgcag cagaccgttc acgacctcgt tgaccgtgcc gtcgccgccg
      241 agcgccacca cgagatcgat gtcacggctc tcggcggccc gccggccgag gtccttcgcg
      301 tgcccgcggt actcggtggt gaccgcctcc agcttcatct cgctggccag cgcgtggatc
      361 aggacgtcac gcgtgcgcgc actggtggtg gtagccgccg ggttgaccac gagaagtgca
      421 cgcatgggcg ccagactacc taccgggggg taccggggcg cacctgggcc ggaccgcccg
      481 ccccgggtcg gggccccgcg cccgggctac cctggccggg tgagtactga gcagaccccc
      541 gaagcccccg ccgaaccgcg ccccggccgg ctgaccgccg cggcggcgct gtccgcgctg
      601 gaggggctcg ccctggtcgc cggtgggctc ttcatgctcg tgatgggcct gaccggcaag
      661 cccgacaagc ccacccaggc cgaaatgggc ggcctgacgc tggtggtcct cggcctgatc
      721 ccgctgatcg ccgcccgcgg actgctgcgc cgccgcagct ggagccgggg cccggcgatg
      781 atcacccaga tcatggcgct gccggtggcg tggatgttcc tcaactccga cggggcgccc
      841 tggatcccgg ccggcatcgc tctcgcggcg gcggccatca ccggtctcgt actcctggtg
      901 aacccggcca ccacccaggc gctgggcatc cgcgggccga tgcgggacgc gtgagcgcga
      961 agggtccgcg ggcgcgcccc cggaccccgg ccgctccgcc gcgcgaagcg gctactcctc
     1021 cacgaggagc ttgtcccgca gctgggccag ggtgcgggcc agcaggcgcg agacgtgcat
     1081 ctgcgagatg ccgacctcct gcgcgatctg cgactgggtc atgttgccga agaaccggag
     1141 cagcagaatc cgcttctccc gcggcggcag gtcctcaagc agcggcttga gggactcgcg
     1201 gtattcgacg ccttcgagcg cctcgtcctc cgcgcccagg gtgtccgcga ccgcgggcga
     1261 ctcgtcgtcc gtgtccggca cgtcgaggga gagcgtggaa taggcgttgg ccgactccag
     1321 cccctccagg acctcttcct ccgagatgcc gagccgctcc gccagttcgt gcaccgtggg
     1381 cgagcggccg tgctgctggg acagctccgc cgtcgccgtg gtgagcgcga gccgcagctc
     1441 ctggagccgg cgcggcaccc gcaccgccca gcccttgtca cggaagtgcc gcttgatctc
     1501 gccgacgacg gtgggggtcg catacgtcga gaactcgacg ccccgctcgg ggtcgaaccg
     1561 gtccaccgac ttgatcagac cgatcgtggc gacctgcgtc agatcgtcga ggggctcgcc
     1621 acggttgcgg aagcgccggg ccaggtgctc gaccagtggc aggtgcatcc gaaccagctg
     1681 attgcgcagc tccgccttct cggacgagcc gtcgggcagc ttgcgcagct cgaagaacat
     1741 cgcccgcgcc ccgctgcgat cgtgtggatc gtgatgcctg tgctcgatgt gctcgctcat
     1801 aagggccgcc cgctctgcct gctccgccgc gtacaaaacg ccatctgggc catccacagg
     1861 gctgtccacc gggtgcggcc gggcctgctg ctccgggatg cccacggggc gcaccgcttc
     1921 cggagtgcgc tcgtcgtccc gcaccggacc ctccccgctc acgccggtcc gggtcccgcg
     1981 ccgcgctgtt tgtacaggct gatggagacc gtacggtcct cggccacggt ggattcgacc
     2041 ttgccggcca atgcggagag caccgtccac gcgaaggtgt cgcgctccgg cgcccggccg
     2101 tcagtggtcg gcgccgagac ggtgacctcc agcgagtcgt ccacgaggcg gaagacgcag
     2161 ctcagtacgg aacctggaac ggcctgctgg agcaggatcg cgcaggcctc gtcgaccgcg
     2221 atgcgcaggt cctcgatctc gtcgagggtg aagtccaaac gtgccgcgag tccggccgtg
     2281 gccgtacgca gcaccgacag gtaggcaccc gcggccggca gccggacttc cacgaagtcc
     2341 tgattcccgg gctcgcctgc gatctgggac accctcacct ccaaggtggc acaagctctc
     2401 tcgaggccca aggagggggg aagtcccggg gccgtgggta cggggtccgt acctggactg
     2461 gcgacgctat cgcgatccat ggtgccctgt cgccggaagc tctcccggcg actgtcactc
     2521 atggtaagcc tatgagtacg gacagtggct agaggtttgc agtgcccaat tgcggtgaag
     2581 cgggaccggg ttgacgtacc caggcgccgg gcgcttcgaa ccttcccgtg cgtcccttac
     2641 gcatcggacg tggaacgtgg gaggccactc tcacaccagc aggccgtcca cgaagcacca
     2701 gcgccagctc tcgccgggct cgaaggtccg catcaccgcg tgaccggtct cctcgaagtg
     2761 gcccgtggcg tgctggtgcg gcgaggagtc gcagcagccc acgtgcccgc agaccaggca
     2821 cagacgcagt tgtacggggt gcgtaccgtc cttcaggcac tccggacagg tgtcgttcag
     2881 cggggccggc tcggggcgcg gcagttctgc aacgtgcggg cactcgctca tgatggccag
     2941 gttacgacgg agcgcggggc gctggtggac ggggacggac ggatctgatg gatgcattgc
     3001 cgctggtggc gctgatcgcg gcgagtgcgg cggtcgcggg ggcggcgcgc aggtcgccgg
     3061 tgcccgcgcc cctgctcctg gtggcggtgg gactgatcgg ggcgtacgtg cccggggtgc
     3121 ccgcctacac cctcgacccg cacatcgtgc tgccgctggt gctgccgccg ctgctgcaca
     3181 cggccgccct ggagagttcg tacctcgatc tgcgggccaa cctgcggccg gtggcgctcc
     3241 tctcggtcgg ctacacgctg ttcgcgacgg tggcggtggg atacctcgcc tacctcctcg
     3301 tgcccgatct gccgctgacg gccgcgctgg tgctcggcgc ggtgatcgcg ccgccggacg
     3361 cggtcgccgc caccgccatc gcgcgtcggc tgcgcctgcc gagccgcatc accacgatcc
     3421 tgcagggcga gtccctggtg aacgacgcga ccgcgatcac cgcgtacaag gtggcgctcg
     3481 cggcggccgt cggggcgggg gccacctggg gcggcggggt caaggagttc gcgctcgcct
     3541 ccatcggcgg ggtcggggtg gggctcgtcc tgatgctgcc gatccactgg ctgcgccgcc
     3601 acctccacga ggcgctgctg cagaacacgt tgtcgctgct catcccgttc gtcgcgtacg
     3661 cggcggccga gcaggtcggg gcgtccggag tgctggccgt ggtggtcgtg gccctctacc
     3721 tcggccaccg gtcctggcag gtggacttcg cgacccggct ccaggaggag gccgtctgga
     3781 agatggtctc cttcctcctc gaatcggcgg tgttcgcgct gatcggactg caaatgccgg
     3841 tggttctcaa gggacttggg gagtacgggg tcggcgaggc ggtctggtac gcgatcgggg
     3901 tgttcgtcct ggtggtggcc gcccgcttcg tctgggtctt cccggccacg ttcctgccgc
     3961 gcgcgctgtc cgagaagatc cggcgccgcg agccggagac ggactggacg gccccggtga
     4021 tcgtggggtg ggccgggatg cgcggggtgg tctcgctggc catcgccttc tcgatcccgc
     4081 tgacgatggc ggacggttcc gccttcccgg cgcgcaacct ggtcctgttc ctgaccttca
     4141 ccacggtcat cggcacgctg gtcgtgcagg gcctcaccct gccgccgctg atccggctgc
     4201 tcaagctgcc cggacgggac acgcaggccg agacgctggc cgaggcgcag gcccagagcg
     4261 aggcgtcccg ggcggccgag gcgcgcctgg acgagctgct cgccgacccg cgcagcacgc
     4321 tgccaccgcc gctcgcggac cggctgcgga cggtcctgga gcggcgccgg aacgcggtgt
     4381 gggagcggct cggggcggtc aacgaggtga cgggggaatc ggcggacgcg acgtaccggc
     4441 ggctgtcgcg ggagatgatc gaggcggagc ggaaggtgtt cgtgtccctg cgggatgatc
     4501 gccgtattga cgacgagatg atgcggacgt tgctgcgcag gctggatctg gaggaagcgg
     4561 cggcctaccg cgaccccggg acgtagccgc ctccccttgg ggctccgccc caaaccccgg
     4621 ggggtttgcc cgcctgcccg cccgttgccc ggggttggtt ggttccgggt tcccctgggg
     4681 ctccgcccca gaccccgttc gcgcctcaag ggcgctcgtc ctcaatcgcc ggacgggctg
     4741 taggtgcccc agcaccgggt ctttcagggg ccgacatccc cggacgggct gtaggtgccc
     4801 ccgcaccggg tctttcaggg gcgcggggaa ctgcgcgacc ggccacgcac ggtccgcagt
     4861 cgaactcctg ccacgcgtct cctcaccccc ggagggttgc gggaaggggt ggggtggggc
     4921 gaggaccggg gtccggggcg gagccccggc gcatcccggc cccggcgggg cctgtcacgg
     4981 gcggccggtg atgacggccg tcagcgtcgt gccccgggtg aacgatccct cctgcgtcag
     5041 cgcgtgcagc gcgaagagca ccttcgccac atacacccgc tccaccccca ccccgtgccg
     5101 gtcctcgaag tcccgggcga acgactccag ttcgggaggc acccgcgcgt acccgccgaa
     5161 gtggaagcgg tcgtccaggg tccagatgcc ccgggggccg ccgaaggcgg cgcgctggag
     5221 ggcgtcgacc tcctcggcga ggaagccgcc cttcaggacc ggtaccccga tcgcccgctg
     5281 ggcggggccg aggccggcgg cgaggcccgc aagggtgccg ccggtgccgc aggccacggc
     5341 ggcgacgtcg gtcgagccgc gcagctccgc gcccagctcc gtacagccct gtgccgcaag
     5401 ggagttgctg ccgccctcgg ggacgacgta cgccccgggg gcgaggaggt cgaggaggcc
     5461 cgccaggacc tccgggtcgg acttgcggcg gtaggtcgcg cggtccacga agtggagccg
     5521 catgccgtcc gccgcacatc gcgcgagcga gtcgttgagc gggcggccgg ccagttcgtc
     5581 gccccgcacg acgccgatcg tggggaagcc gaggagccgc cccgccgcgg ccgtcgcgcg
     5641 gaggtggttg gagtaggcgc cgccgaaggt gaggaccggc cggccggccg cggcccgcag
     5701 gttcggcacc agtttgcgcc acttgttgcc gaccagggcc gggtggatca ggtcgtcccg
     5761 cttgagcagc agccgcaccc cgtgccgcgc gaagcgctcg tccgtcacct cctccagggg
     5821 ggaggggggg cggggggcga gcgcttcggg ggtcatgcac ccattgtcac gtcagtcacc
     5881 cgctgtcact tcaggcgctc gtgcacgcgt tcccgcagcc agtccatcgt gaagccgcgc
     5941 gggtcgatct tgccgacctg ccactccttg tgaccgatga ccgaacgctc ggtccagccg
     6001 tagtgacggc acacggccgc ggccgccttc tcgatggctt cgagctgggc ctcgggccag
     6061 gggtccttgc cgtcgcccag gttctcgcac tcgaagccgt agaagtgcgt gttcccgtcg
     6121 gtgtcgttcg tcagcggctg cggcagccgc ttctcggcga tcaccgcgcg cagcacgttg
     6181 ccgtcccccg cgcccgcgtg gttggcgcgg ccgttgccga cgaggtggac cgtgccgtcc
     6241 ttggtgatca ccccgtggca gagcgggccc ggcagggagt cgtagccgtc gtagcagatg
     6301 cggaccgtgg cgtcggcgcc gctggtggcg gtgtggtgga tgacgacgcc gttgatcggg
     6361 gcccagccgc cgtggccggc ccggttgtgg gtgcgccact ggccgacctc gacgacgcgg
     6421 aggccctcgg cgcgcagggc ggcgaggaat tggtctgcgg acatgggtgg ggccatggcc
     6481 gcctccttcc agagcggtgc ggaatatctc gtaccgcttg taccccaact cccgctatgg
     6541 ggcgatctgt tcggtttgcc gtgcgagctg atccggacag ccccgcgccg tcgaagggcg
     6601 ggtcagtcct gggccagcca caggtcgggg ccgaacacct cgtagtggac gtcggccgcc
     6661 cgcacaccct tggcgaggag ctgggtgcgg accgcgcgca tgaacgggag cggcccgcag
     6721 aggtaggcgc gggtgccggg cgcgaccgga aggcgggtga ggtcgaccag gcccgtgcgg
     6781 tcggcgggat gcccgggctc ggggtcctcg taccagaagt gaacggtggc gtccgggagt
     6841 tgggcggtga gagccgcgtg gtcgtcgcgc agcgcgtgct cggcggggga gcggtcggcg
     6901 tgcaccacgg tcaccggggc gcggtggccg tcggccgcca gctgccccag catcgccacc
     6961 atcggcgtgc agccgatccc cgccgacgcg agcagcagcg gggacccgtc ggcgtcgagg
     7021 acgaggtcgc cgtacggcgc cgagacgcgc agcccgtcgc cctcgcggag gtgggcgtgc
     7081 aggtggccgg aaacctcgcc gtccgggtcg ccctggacgc gcttgacggt gatcgagcgg
     7141 agctcgccgc cgggtgccga ggtcaggctg tactggcgga tctgccgtgc cccgtcgggg
     7201 agttcgacct gtacggagac gtactggcca ggtttgaagg cgggggccgg ggcgccgtcc
     7261 gcggggcgca gccggaaggt ggcgcaggtg gccgtctcct cggtgcggcc ggccacggtc
     7321 cactcgcgcc agacgtcccc ggcgagcacg ccctgctccg cgtagagccg ggcctcgatg
     7381 tcgatcaggg cgttcgccat cagccagtac acctcgtccc acgcctcggc gacctcggcg
     7441 gtggccgcct cgccgagcac ctcggcgatc gcggcgaaca ggtgccggtg gacgatctcg
     7501 tactggtcgg cggtgacgcc gagcgaggcg tgcttgtggg cgatgcggtt cagcatcacg
     7561 tcggggcggt cctcggggtg gttcacgaga tgtgtcgcga acgcggctat ggagccggcg
     7621 agcgcctgct tctggaggcc ggccgcctgg ttgccccggt tgaacagatc gcggagcagc
     7681 gcgggccggt ccgcgaagag gcgctcgtag aaccgctcgg tgatggttcc gacggccgcg
     7741 ccgacggcgg gcagggtggc gcgtacggtc acggtcgact tctcggacaa catcgacggg
     7801 ctcctcttgg tcaacgtctc tggttcggga ttgactgggt tgaatatgca tctggattgc
     7861 atattcaaga aggtgcgtaa gtgccgcgcg gcccggtggc cgacggaccg tcagcggctg
     7921 gtgatgccga gcaggagggg gccggtcggg gcggtcacca gatcgtccac ggtgagctcg
     7981 tccagggact cgtagaacgc ctcctgggcg cggtgcaggg cccggcgcag acggcaggcc
     8041 gcggccagcg gacacggtgt cgcgccctcg cactccacga cgtcgcccgg accttcgagc
     8101 tcccgcacca ggccgcccac ggaagcgagg tggcccgccg cggtgactgc gagtccgccg
     8161 ccccggccgc ggcgcgcctc gacgaggccc aggtgctgga gccgtgcgac gaccttcgcg
     8221 gtgtgggtgt acgggatgcg catcgcgtcc gccacctccc gcgtggtcgg cgggacctgg
     8281 tcggccgcgt tctcgatgac cgccaggcgc atcaggacgc gcagcgccag gtcggtgaat
     8341 ctggtgagcc gcatgcctga agcgtagata acttgcatct gctgtgcaaa ttaaaggcgg
     8401 acggctgccc ggtccactgg tcttctaatc ccactcattt gagtaatggc gcggggactc
     8461 tccgtgctgg aagtgttctc cacgcagttc agcttgaaga tcgtgagagc gctcagaagg
     8521 agtcacatgt cggtcgaggc aggtcccgag aaccgcaccc agcagagtct cggcacagcc
     8581 gccgcgcgga acttggcgac caccaccaag tccgccccgc agatgcagga gatcacctcc
     8641 cgttggctgc tgcggatgct gccatgggtg caggtgcagg gcggcacgta ccgggtcaac
     8701 cgacgcctca gctactcggt gggggacggc aggatcacct tcgtccagac cggtgagcgg
     8761 gtcgcggtca tccccgcaga gctgggcgag ctgcccgcgc tgcgggacta cgaggacgag
     8821 gcggcgctcg gggagctcgc caaccggtgc gagcagcgcg agtacgccgc gggcgaggtc
     8881 atcgccaccg cgggcgacgc gaccgaccgg gtgttcctgc tcgcacacgg ccgggtcgag
     8941 aagatcggca ccggccagta cggcgacgag accgagctcg gcttcctcgc ggacggggcg
     9001 cacttcggcg aggacgcgct cgtctccggc gaagccgtct gggagtgcac ctaccgcgcc
     9061 accaccggct gcaccgtgct cgtcctgagc cgggccgacg tgctcaacct cgcggagcgc
     9121 tccgagtcgc tgcacgacca cctcgcgtcg gtcaccgggc tgcccgagca gcgcaccaac
     9181 aactacggcg aagccgcgat cgacctgtcc gccggccacg tcggtgaagc gatcatcccg
     9241 cacacctacg tcgactacga gggctcgccc cgcgagtacg aactctccgt cgcgcagacc
     9301 gtcctcaagg tccacagccg cgtggccgac ctctacaacc agccgatgaa ccagaccgag
     9361 cagcagttgc ggctcacggt cgaggcgctg cgcgagcgcc aggagcacga gctcgtcaac
     9421 aaccgggagt tcggcctcct gacgaactgc gactacgagc agcgcctcca gccgcacgac
     9481 ggcgtgcccg gccccgacga catggacgag ctgctctcgc ggcggcgcgg ttccaagctc
     9541 ttcctcgccc acccgcgcgc catcgccgcg ttcggccgcg agtgcaacaa gcggggcctg
     9601 gtgcccgagt cggtggaggt cgcgggccac cacgtgccgg cctggcgcgg ggtgccgatc
     9661 ttcccgtgca acaagatccc ggtcagcgac gcccgtacga cctcgatcat ctgcatgcgt
     9721 accggcgagg ccgagcaggg cgtgatcggg ctccagcagt ccggcatccc ggacgagatc
     9781 gagccgagcc tgtcggtccg cttcatgggc atcgacgagc aggcgatcat ctcgtacctg
     9841 gtcacggcgt actactcggc cgcgatcctg gtgcccgacg cgctcggcgt cctggagaac
     9901 gtcgaggtca gccgctggcg gtgagcctcc ggtccgggcg cgccgacccc ggcgtgcccg
     9961 gtgccgccga caactcccag gaaaggcaac ctagttggcc atgccggaag ccatggaggg
    10021 ccgcgaggcc ggtgacctcc tggagcgggc ccgtaccgtc gtcgaccccc aactgcgcgc
    10081 cagcgtcgca tcgttgcccg gttccatgcg gcgggtggcg atgtaccact tcggctggga
    10141 gcacgcggac gggaccccgg ccggcggcca gtcgggcaag gcgatacgcc ccgccctcgt
    10201 cctcgccgcg gccacggcgc tcggtgggcg gccggaggcc gcggtacggg cggccgccgc
    10261 cgtcgaactc gtccacaact tcacgctgct gcacgacgac gtcatcgacg aggacgccac
    10321 ccggcgacac cgcccgaccg cctggaccgt cttcggcacg ccggacgcca tcatcgtcgg
    10381 cgacgccctg ttcgccctcg ccctccggct gatcgccgac gacggccatc cggcctcggg
    10441 cgcggcatcc gcccggatcg cggcctgtgt catcgaactc tgcgcgggcc agcaggccga
    10501 ctgcgccttc gagcagaggg gcccgcagga cgtctcgctc gacgagtgca tcgccatggc
    10561 catggccaag accggcgccc tgctcggctg cgcctgcgcg ctcggcgcgc tgtacgcggg
    10621 cgcgggagac gaggaggtcg ccgcgatgga cgcgttcggc cgggaggccg ggctcgcctt
    10681 ccagctcatc gacgacctca tcggcatctg gggcgacccc ggtcgcaccg gcaaacccgc
    10741 gggagccgac ctcgccgcgc acaagaagtc gctgcccgtc gtggccgcgc tcaactcggg
    10801 caccccggcg gccgccgagc tcgccgagct gtacgggggc ccgatgggag cggaggcggt
    10861 ccgcagggcg gccgacgcgg tggaccgcgc gggcggccgc gactgggccc aggtgcacgc
    10921 cgccgaccgg atggcccggg ccgtcgacca cctctcgcgg gcggtgcccg atctcaccgc
    10981 ggcgggcgaa ctgctcgccc tggcagagtt cgtgacccgc cgcactcgtt gatccgtggt
    11041 ggcggccggt ctcgtggccg gtctcgcggc ctgtctcatg acctgtctcg tggccggtct
    11101 cctcgcggcc gaagtggccc agtgaagtcg aagccgagtg gccccaactc cgggccactc
    11161 ggcttggttt gatgggctca tgacctcccg cctcctgccg cccgccggcc ctgcccgcgg
    11221 tctcgccacg gcccagctcg tcaactccct gggcgacggc gccttcctgg tcacctcggc
    11281 gctgtacttc agccgcgtcg tcggcctgcc ggccacccgc atcggtctcg gtctgaccct
    11341 cgcctgggcg gtcggcgcgc tcgccggggt gccgctcggg cagctggccg accggcgcgg
    11401 cccgcggacc gtcgccgtcc tgctcgccgc ggccacgggc gcctcggtcg cgtccttcct
    11461 gttcgtccgc ggcttcctcc ccttcgtcct tgccgcctgc tgctacgcga ccgcacagac
    11521 cgggctctcc gcggcccgcc aggcgctcct gtccgcgctc gtcgaccgcg gggaccgcac
    11581 cagggtcctg gcgcacctcc agtccacgct gaacgccggg ctcgccgtcg gcgcggcgtt
    11641 cggcggggtc gccctgcact acggcacccg caccgcctac ctcgccgtgt tcgccctgga
    11701 cgcggtggcc ttcctgttct gcgcgctcgc cctgatgcgg ctgccccacg tgccgccgag
    11761 gcccgtcgtg cccggcgggg ggcctcggtt cgccgtgctg cgcgaccgcc cgtacgccgt
    11821 gatcaccttc ctgaacaccc tgctcctgct gcggatgcca ctgatcagcc tcgccgtccc
    11881 gctgtggaca gtcacccgca ccgatgcccc gggctggctg gtgtcggcgc tgctggtgct
    11941 caacaccggt gccgtgatgc tcttccaggt ccgtaccgcc tccgccgtgc gtgatctgcc
    12001 cagcgcccgg cggaccgtgg cgcgcggcgg ggtgctgatg ctggcctcct gcgcggcgtt
    12061 cgcgctcagc gccgccggtg cgtcgccctg ggccgccgtg ggcgtgctgc tcgtcgcggg
    12121 cgcgcttcag gtggcgggcg agatgatgca gtccgcgggc gcctggcaga tcggcttcga
    12181 cctcgcaccg gccgatcaac aaggccagta ccagggcttc ttcggcatgg gcgtgccgct
    12241 ggccaggatg ctcgggcccc tgctgctcac cgcgctcgtc atcgactggg gcgtgcccgg
    12301 ctggctgctg ctcggcgcgc tgttcctcgg cgccggcctc gcgctcgggc ctgccgtccg
    12361 ctgggccgag cggtccaact ccgcgctggt ggcggctggt tgaagcagtc atggcgggcg
    12421 ggggcggcgg agatgggggc ggacgtgtcg aagcgcgcaa ggaagcggta acacccattt
    12481 cggtcacccc ctgtgacgaa tggcagggtg cgccgctaat ctccgcccat gacaccacag
    12541 tcatgggcgg gttggtatcg agaccgccta ggatcagaag cgctgacgat caccacggac
    12601 gggacgcaac tgcggacccg gatcaggggg gtcgacttcg ccggagcgag cttcgactcg
    12661 ctcggcccgg taccggggat accggcggag agcggtgcgt tcgcgctcga cgacgggaac
    12721 ctccgtgact tcgtactcga atgggacatg cccgtcccca tcgcctcgga cgacggcgcc
    12781 gtccaggagg ccaccctcag ctgcctgctg tccctgaaac cgccggagcc cgacctcggg
    12841 gtcgcgctgc acttcggggg agcggtttac gccagcgggc gggccgaagt cgacttcggc
    12901 tcggtgctcg ccgacatccg gcgccaactc ccgtccggtt caagcctcca gccgtccgct
    12961 ctggacgcca tatagctcaa ccccccgtcc ttttctcccg cggccgccgc gcatcgggga
    13021 gtccgtccga ctccccgatg cgcggcggcc gctctgtatc cggagctgaa cagggctcgc
    13081 gacggggcga gttgggggac cctgagcgtg cattgttcta ctatcatgcg aacaaggagg
    13141 tttcgatgat ccgtgtccgc cgcctgaccg ctgtcgccgc gctcccgttc ctgctcgccc
    13201 tggccgtcga cctgacgctg tacgtgcttc tccgtgaccg actgcccgac ccgttggcca
    13261 gtcacttcac cgggaaaggt cgctccgacg gcacgcagag ccgtggctcc accccggtct
    13321 tcgcgtgcgt gctgcacctc ggcctcggcg ccctgtgggc cggcatggcg gccgtcggag
    13381 accctgccgt acgccggctc cggtggctga tcgccgccgg gtacgcgacg gccgggttcg
    13441 tgggctacct cctggccgcc acgctgctcg ccaacgcgga cgcgaccgac ccggcgcggg
    13501 tgcggctgcc gctgtggcag atcgccgtcg gcgcgggcat cgcggtgctc gcggcggcac
    13561 tcgggcggct gttgctcttg gccgtgccga ctccgccccc cgagccctct tcgcgtccgg
    13621 acgccgaccg gaccccgcgg ctcgacctcg ccgagggcga ggtggcgggg tggatgcggc
    13681 gggcgccctc gcgtgtgctg ctcgtctgcg ggaccctgct gctcgtcgct gcgggcgccc
    13741 tgctgttcgc cgttggcccg ggcaatgcgg tgggcgcgtt cttcggtgcc gtggtgtgcc
    13801 tcgtcttctc ctgcccgtac gtcaccatcg accggcgggg cctgaccgcg cggcccaccg
    13861 cgctgccctg gccgcgcatc agaatcccgc tgtccgacgt ggaccgggcg gtcagccgcg
    13921 acatcaaggt cctcgcggag tacgggggct ggggctatcg ggtgcgtgcg ggcaagtcgg
    13981 ggctcatgct gcgctccggc gaggcgatcg tcatacggcg gtcggacggg cgggagttcg
    14041 ccgtgacggt ggacgacgca gggacggccg ccgccctcct gaacacactg gcccggcgcg
    14101 cggaggcgag ggactgatgc tcttccgtgt ggaccccgcc tcgccgaggc cgctcggcga
    14161 ccagatcgcg gcctcggtgc gcggggcgat cgccgacggc aaggtgaccc cgggcgaacg
    14221 cctcccgtcc gcccgttccc tcgcggatct gctcggggtc aacgtccata cggtgctgag
    14281 ggggtaccag cggctgcgcg acgagggcct gatcgagctg cgccggggcc gcggtgcggt
    14341 cgtcgtgcac gacacccggg cgcggggccg ggcggagctg atgctcaagg tgcgggaact
    14401 ggtcgatcag gcacgggagt tggggctgac cgaggacgag gtcgtgggac tggtgcggcg
    14461 cggcctcgcg tgaccgtgcc ggctcgcgga ggcggcccgt gtccccgggg ccgtcagtac
    14521 gtctggagtt ccaccaggtt tccggccggg tccagcaggt gcgcggcgcg catgcccggg
    14581 ccccactccg gcaggtcccg cacgggcacg gccacggggc cgcccgcctt cgcgcacagc
    14641 gagaccgcgg cgtcgagggc gtcgcgcgtg gccatgtgga tcaccaggga cgcgcccccg
    14701 cccggcatcc ggccctcgcc gagcacggcg gccatcgcgg agcgggtgaa cagcgcgagt
    14761 gcggtgcgcc cgtcgggggc atcccaactg gcgtatccgg aggcggagtt gccgcgggcg
    14821 agggtgcagc cggtgaggtc aggcaggacg gcgtcgtaga agcggaacgc cggttcgtac
    14881 gggtcgacga gaagccgcgg gtacggaggc tccagagggt ccatgccctc gaacctaacc
    14941 cggaagacgg ccctccgcgg tgtgccagtg gtcacgcgtt cggagccgga acgggcccgt
    15001 tccggggcgc gggctcaggc gggccgggcg taccgctcgg cgatcagccg ggcgcaggcc
    15061 atggactccg caccggccga gtccacctcg atgtcgtacc gcacccccac gtgcacggac
    15121 tcggcctggc cccgggccat gccggggacg cggtcgccac gggcggtctc gcggcccgcg
    15181 gccgtgtcgg gggcgcagcg caccccgacc cagagcacgt cgagcccgtc gagggcctgc
    15241 tgccagcgct tctgggcgtc ggcgccgtcg aggaagatct cgtcgagcac cacgcgggca
    15301 ccggcccgca ccatcgcggc caccccgcgt gcccaggcgt ccgagagccg acggtagtcg
    15361 gggcccacgg tcaccgtgcc gtccgctccg atctccaggc cgccctcgcc gcggagcgag
    15421 gcgggcatgg ccgcgtccac cgagtcgacg ccgaaggcga gccaggcgcc gggcagcacg
    15481 gcctgcaggc accggacgat cccggacttg ccggaactgg acccgccgtt gagcacgatc
    15541 acctggcacc ggggcgtacg cgtctgatcc gtcacgcgcg ccacggtagg cgccggcccc
    15601 ggcccggcca agcgaattcc gcgcgcgata gcctgccccg atgcggcgca tcctcgtggt
    15661 cggcagtacc ggagccggca agtccaccct ggcgcacgag ctgggcgagc ggctcggggt
    15721 gccgtaccac gagctggacg ccttgcactt cgcgggcccg ggctgggcgc gggacccgca
    15781 cttcgccgcc cgcgtggccg agatcgcggc caccccggcg tgggtcctcg actcgtacgg
    15841 cacccccgat gtccgccccc tgctgtggga gcgcgccgac acggtggtct ggctggacta
    15901 cccccggcac gtcgtgatgc cccgcgtgct gcgccgctcg ctgcgcagga ccgtgctgcg
    15961 cgagcggatc ttcaacggca accgcgagac gctgagggag tggttccgcg gcgaccaccc
    16021 ggcccgttgg gcctggtccc agtacgcgcc ccgcagagcg gccctgacgg ctctcaccac
    16081 cgacccggcc ctcgccccgc tgcacaccct gcgcttcacg gctccgcgcg aggcacggcg
    16141 gtggctgcgc acgatcgggg ccggccgcgg cgaacgccgg aagggcccgg ccgggtaacc
    16201 ccggtcgggc ccttctcgat tcgccggtgc tcggccgccc gaaggcgccc ggcctgcgaa
    16261 ctcgacctgg atcaggcctt cttggtctcc cagaagatgc ggtcgatctc ggcgatgagg
    16321 tcgagcgcct tctgtccggt cgccgggtcg gtcgacgcct tggcggccga gagggccttc
    16381 agggtgtcgt tcaccagctg gtggagctcc gggtacttct cgaagtgcgg cggcttgaag
    16441 tagtcgctcc acagcaccga cacgtggtgc ttggcgagct ccgcgcgctg ctccttgatg
    16501 accacggcac gggcacggaa gtgcgcgtcc tcgttggcct ggaacttttc ctgcacggcc
    16561 ttgaccgact ccgcctcgat gcgggcctgg gccgggtcgt acacaccgca gggcaggtcg
    16621 cagtgcgcgc tgaccttcac cttgggggca aacaggcggg aaagcattga gctgtccttc
    16681 ctcgtgatcg tcttctcagg tgggacatta ctcggtgaga ggcggtattt cgcgggtgcc
    16741 cccatgggct taggtcaaaa gtccaggggc accccgggac tcgtggcgga acgtaccgtg
    16801 ggatcggcgg cggggtgccg gtggccggga ggtgggtgag gtatgacgga tgaggggcgg
    16861 gagccgaggg tgccgttggg gatcgcggag gtcctcggga cctcgatggt tcccacgctg
    16921 ctgcacgggg atcagctgct cgtgcactac ggcgcggagc tgcggatcgg cgacgtggcc
    16981 gtgctgcggc acccgctgca gcaggatctg ctcatcgtca agcggctcat ggagctgcgc
    17041 gagagcgggt ggtgggtgct cggcgacaac accgacgacg aggtcgtgga cagccgggcc
    17101 ttcggtgcgg tgccggtcga cctcgtgctc ggacgcgtgc gcggacgcta ccggccgatg
    17161 gcggcggggc gccggcgcac ggtcggctac ctggcgtcct gggcggtctc ctcggtgagg
    17221 cccgtgctgt cggaccgctc ggtctccaga cgcttgcggg cccggtaggc ggccacgttg
    17281 gcccgggtcg cgcaccggtc cgagcagtag cggcgcgagc ggttggtcga ggtgtccagg
    17341 taggcgttgc ggcagggcgc cgcctggcac aggccgagcc ggtcgacccc gtactccgtg
    17401 aggtggaagg cgagccccat ggaggcgatc gcggcgtagc ccgccgtcgc gttcgagggg
    17461 tggtcggcga ggtgcatgtg ccacagcggg cggccgtcgt cgtcgcggtg ctcgtggccc
    17521 gacacctggg ggctgaccgg gaattcgagc agcagcgagt tcagcaggtc caccgcctgg
    17581 acctcctcgc cccggtccgc cgcctcgaag accgcccgca gccgggcccg taccgaacgg
    17641 aagcgcgtca cgtccgcgtc cgtcgcccgg cgggccgcgg actggttccc gccgaacagg
    17701 tcccggaccg cctcgaccga ggtcagggcg tccttgctgc gggccggctc ctcggtgttg
    17761 accaggcgca cggcgtagtc cgagtaatag gccagttcca cttgtagtcc ttacggcggc
    17821 ggtctatggt ctgagctgtc cacaagtaac ggctggatac cctttgaggg tattacagac
    17881 tggctgtgta ggagggatcg cggtgtcgga gactgtcact ggtgccggaa cgggcaccga
    17941 ctggcggggc tggcaggaca gctgggaccg gcagcaggag tggtacatgc cggaccgcga
    18001 ggagcgcttc cgggtcatgc tcgacatggt cgaggcctgc gtcggtcccg cgccgcgcgt
    18061 gctcgacctc gcgtgcggta cggggagtat tacggaccgg ctcctccgga ggttcccgga
    18121 cgcggtcagt accggggtgg atctcgaccc cgcgctcctc gccatcgccg agggcacctt
    18181 cgcgggggac gagcgggtca ccttcgtcgc cgccgacctc aaggacccgc actgggtcca
    18241 gtcgctcccg tacgactcct acgacgccgt cctcacggcg accgccctgc actggctgca
    18301 cgcggagccg ctcgccgcgc tctacgggca ggtcgccggg ctcgtccggg acgggggcgt
    18361 gttcatgaac gccgaccaca tgatcgaccc cgcgaccccg cgcatcaacg ccgccgaacg
    18421 cgcccaccgg catgccggga tggaccgcgc caaggccggc ggcgccctcg actgggcgca
    18481 gtggtgggcg ctcgccgccg cggacccggc cctcgccggg ccgaccgcca agcggtacga
    18541 gatctacggc gagcacgccg acggcgacat gcccgccgcg ggctggcacg ccgagaccct
    18601 gcgcgcggcc ggtttcgccg aggcccgccc ggtctgggca tcgccttcgg acaccctgct
    18661 gctcgccctg aagtagccga cgggaaaggg gggttacggg cgccggcccg taacccccct
    18721 tgttcatgcg gtccttacag caccttcgac aggaacgact tcgtccggtc gtgctgaggg
    18781 ttcgtcagga catcgcgcgg atggcccgct tcgacgacca cgccgtcgtc catgaagacc
    18841 agcgaatcgc cgacctcacg cgcgaagccc atctcgtggg tgaccacgat catcgtcatg
    18901 ccgtcctcgg cgagaccgcg catgacgtcc aggacatcgc ccaccagctc ggggtcgagc
    18961 gccgacgtcg gctcgtcgaa gagcatcagc ttcgggtcca tcgccagcgc gcgggcgatc
    19021 gccacgcgct gctgctggcc gccggagagc tgcgacgggt agttgcccgc cttgtcggcg
    19081 aggcccaccc ggtcgagcag cttcagggcc cgctcgcggg ccaccgcctt cgactcgcgc
    19141 ttgacctgga ccggcgcctc catgacgttc tcgacggccg tcatgtgcgg gaacagattg
    19201 aagcgctgga agaccatgcc gatgtcccgg cgcttcaggg cgacttcgct gtccttcagc
    19261 tcgtagagct tgtcgccctt ctggcggtag ccgaccagct cgccgtccac gtagaggcgc
    19321 ccggcgttga tctgctccag gtggttgatg caccgcagga acgtcgactt gccggagccg
    19381 gaggggccga tcaggcagaa cacctcgccc tcggccacct ccaggtcgat gcccttgagg
    19441 atgtgggcgg ggccgaacga cttgtggacg ccctcggcct tgaccatcgg ttgtgcagtc
    19501 atggggtcac cgccgccagt gggagaggga gagcaggttc gacttgatgc gctgcagcgg
    19561 tgtgggcggc agggagcgca gcgaaccgcg ggcgaaacga cgctccaggt agtactggcc
    19621 gacgctgaac acactggtca gggccaggta ccagatcgac gcgacgaaga gcatctccat
    19681 caccgcgaac gaggtcgccg cgacgtcctg ggcgctgcgc agcagatcct ggtactggac
    19741 ggcgacgacc agggacgagg tcttcagcat gttgatgaac tcgttgcccg tcggcgggat
    19801 gatcacccgc atcgactggg gaagcaccac gcggcgcatg gtctgcatct gggtcatgcc
    19861 gagcgcgtgc gaggcctcgg tctggccctc gtccaccgac tggatgccgg cccggacgat
    19921 ctccgccatg tacgcaccct cgttgaggcc gaggccgagc agggcggcga ggaacggagt
    19981 catgaccgcg gtcatgtagt ccttgtagaa cccgaggttg aggatcggga agatcagcgc
    20041 caggttgaac cagatcaaca gctgtacgta gaccggggtg ccgcggaaga accagatgta
    20101 cagccaggcg accgaactgg tcaccgggtt cttcgagagt cgcatcacgg cgaacagcac
    20161 gccgaggatc agacccacgg ccatggagac cacgctgatc agaatggtgt gccagaggcc
    20221 ggtcaggatg ctgccgtcga acagcttgtc cgtgacggtc gcccagcgga cgttgccctg
    20281 ggcgaaggcg tagaccagtg cgccgagcac ggcgacgacc actacggcgc tgacccagcg
    20341 gccgtagtgg cgcaccggga tggcgcggat gatgtccggc gggacctgct ccggggcggc
    20401 gtccgccggc cccggagtct tgtcgagctt gtcagtcaca gcgactgccc ttcagtggtg
    20461 cgcgggtcag gagccgccgt tgatggctgc cttggtgacg gcgccctgcg cgccgcccca
    20521 cttgtcgatg gccgtcttgt acgagccgtc cttgatgatc gcgtcgaggg cctcggagag
    20581 ggcgtcgcgc agctgggtgt tcttcttgtc caccgcgatg ccgaacgggc ccgcgtccga
    20641 ggggttggcc accgactcga agtcggcgcc gccgcccgcg gtcttcgcga tgtacgcggc
    20701 gacgggggag tcgttcaggt cggccacggc gccgccggcc ttgacgcggg tctgcgcctc
    20761 ggcgtcgctg gagaaggcct cgacggtgag cttgcccttg ccgtccttcg cgcacttggc
    20821 gacgaggtcc ttggcggcct gctcgtaggt ggtgccgcgc tgcacggcga tcgtcttgcc
    20881 gcacaggtcg tcggtggact tgatgccctc cgggttgccc ttcttgacca ggatgccggt
    20941 gctggccgtg tagtagtcga cgaagtcgac gcccgtaccg gtcttcttgc cgctgtcgtc
    21001 aaggccctgc tggcgcttct tggtgtcgct ca
//
