LOCUS       NZ_CP070373            22469 bp    DNA     linear   CON 18-MAY-2024
DEFINITION  Streptomyces sp. MBT27 chromosome, complete genome.
ACCESSION   NZ_CP070373
VERSION     NZ_CP070373.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MBT27
  ORGANISM  Streptomyces sp. MBT27
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S.S., Hankemeier,T. and van
            Wezel,G.P.
  TITLE     Discovery of novel glycerolated quinazolinones from Streptomyces sp.
            MBT27
  JOURNAL   J Ind Microbiol Biotechnol 46 (3-4), 483-492 (2019)
   PUBMED   30729343
REFERENCE   2  (bases 1 to 8400223)
  AUTHORS   Machushynets,N., Elsayed,S., Carrion,V.J., Siegler,M.A., de la
            Cruz,M., Genilloud,O., Hankemeier,T. and van Wezel,G.P.
  TITLE     New from old: conjugation of actinomycin X2 and anthranilamide to
            form the novel actinomycin L in Streptomyces sp. MBT27
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 8400223)
  AUTHORS   Du,C., Machushynets,N. and van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2021) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   4  (bases 1 to 8400223)
  AUTHORS   Machushynets,N.V., Wu,C., Elsayed,S., Hankemeier,T. and Van
            Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-JAN-2020) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 1.8.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011751035.2-RS_2024_05_18
            Annotation Date                   :: 05/18/2024 03:23:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,575
            CDSs (total)                      :: 7,482
            Genes (coding)                    :: 7,345
            CDSs (with protein)               :: 7,345
            Genes (RNA)                       :: 93
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 39 of 137
            Pseudo Genes (incomplete)         :: 114 of 137
            Pseudo Genes (internal stop)      :: 17 of 137
            Pseudo Genes (multiple problems)  :: 27 of 137
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:14:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 318597
            Orig. end                         :: 341066
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP070373.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from MBT, Institute of Biology
            Leiden, Leiden University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22469
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22469
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22469
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12469](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12469
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(140..433)
                     /locus_tag="GWQ54_RS01450"
     CDS             complement(140..433)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010056642.1"
                     /locus_tag="GWQ54_RS01450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Dabb family protein"
                     /protein_id="WP_167158293.1"
                     /transl_table=11
                     /translation="MIRHLVLFKLNEGVQRDDERVVAGVKAFQELDGLVPEIEFWECAW
                     NITDRPIAYDFAINSAVADADALKRYVEHPAHQAAAGQWREFATWVIADYPF"
     gene            complement(532..693)
                     /locus_tag="GWQ54_RS01455"
     CDS             complement(532..693)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155101.1"
                     /locus_tag="GWQ54_RS01455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_167158291.1"
                     /transl_table=11
                     /translation="MDIKKVLLYIAVVFVLYTIITSPVQAAGMVQTGFEGISSAAKGVG
                     EFMTNLIR"
     gene            complement(1573..2322)
                     /locus_tag="GWQ54_RS01460"
     CDS             complement(1573..2322)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063131.1"
                     /locus_tag="GWQ54_RS01460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_193587918.1"
                     /transl_table=11
                     /translation="MIDMIREQRLAEIFMEVADSLTDDFDVLDLLQRLSTRCVELLDVS
                     AAGILLADAVGELQMVAASDEHTRLLELFALQHDQGPCVECYRSGTARTNIDLNSRGAT
                     ASWPRFAARARETGYVATHAIPLRLRDRNIGALNLFQKTPHLLGESEIALAKALAGVAT
                     ITILQQRTLEQSHIERTQLQTALNSRILVEQVKGILCERWGTSPDEAFSAFRGYARSHH
                     LRLADFAAAIIDGTFDTATIPQPLPRS"
     gene            complement(2319..3059)
                     /locus_tag="GWQ54_RS01465"
     CDS             complement(2319..3059)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073854.1"
                     /locus_tag="GWQ54_RS01465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ANTAR domain-containing protein"
                     /protein_id="WP_167158289.1"
                     /transl_table=11
                     /translation="MISDGMADVLRSLRHGDCGVLAAACARALQVDGVAVSLLVGAGRD
                     AEPEPLWHSPGIAADFEELQFTLGTGPTLDAAHSGTAVVVPDLAAVRADRWPGLPAEAL
                     GLGVAGAYCFPLGLGAIRLGVLTAVTGRADDTVPEQRYADALALAAALTGLLLEHDGGG
                     DGPAVSGSVTGVPRELHRAVVHQATGMVSVQLDVSLADALPRLRAFAYARDLPLGDVAE
                     DVVARRLRFNDDMDGPPELGGRKG"
     misc_feature    3029..3043
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    complement(3058..3073)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.31"
                     /tool="antismash"
     tRNA            complement(3527..3614)
                     /anticodon=(pos:complement(322175..322177),aa:Ser,seq:cga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GWQ54_RS01470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Ser"
     gene            complement(3527..3614)
                     /locus_tag="GWQ54_RS01470"
     misc_feature    3616..3636
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.93"
                     /tool="antismash"
     gene            complement(3673..4101)
                     /gene="tadA"
                     /locus_tag="GWQ54_RS01475"
     CDS             complement(3673..4101)
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /gene="tadA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887718.1"
                     /locus_tag="GWQ54_RS01475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="WP_161244419.1"
                     /transl_table=11
                     /translation="MRSALAGAAQAESAGDVPVGAVVLAPDGTFLASGHNEREATGDPT
                     AHAEVLAIRRAARETGEWRLTGCTLVVTLEPCVMCAGAIVQSRIDRVVYGARDEKAGAA
                     GSLWDLVRDQRLNHRPEVVAGVLEEECSAQLTAFFRQR"
     gene            complement(4146..4694)
                     /locus_tag="GWQ54_RS01480"
     CDS             complement(4146..4694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740985.1"
                     /locus_tag="GWQ54_RS01480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_161244422.1"
                     /transl_table=11
                     /translation="MYFAALLARTEDGWEASDTELDDVETLSDLADLAREAAADGADDT
                     VLVFIEQEDAWFGVVRVDGEEDPRVFVSNAAVAARSSYGAMLTDELLGHDQDDEEDELD
                     TLDLDGTEDGYEDEAATAVDGPDGDEPSDGAVPAGPLGESAILADLGVSEGRLLALDGD
                     ALVTIADALGAAEVLEAVR"
     gene            complement(4923..5102)
                     /locus_tag="GWQ54_RS01485"
     CDS             complement(4923..5102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019992456.1"
                     /locus_tag="GWQ54_RS01485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_161244420.1"
                     /transl_table=11
                     /translation="MPDERDRAQQPESDADRRRRRAQFLRELHEAKALRDRVQPRRARA
                     ARMRQAMRMRTFRW"
     gene            5226..5861
                     /gene="upp"
                     /locus_tag="GWQ54_RS01490"
     CDS             5226..5861
                     /EC_number="2.4.2.9"
                     /GO_function="GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="upp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006141414.1"
                     /locus_tag="GWQ54_RS01490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="WP_100575818.1"
                     /transl_table=11
                     /translation="MRIHVVDHPLVAHKLTTLRDKRTDSPTFRRLADELVTLLAYEATR
                     DVRTEQVDIETPVTPTTGVKLSYPRPLVVPILRAGLGMLDGMVRLLPTAEVGFLGMIRN
                     EETLEASTYATRMPEDLSGRQVYVLDPMLATGGTLVAAIRELIKRGADDVTAVVLLAAP
                     EGVEVMERELAGTPVTVVTASVDERLNEHGYIVPGLGDAGDRMYGTVD"
     misc_feature    5271..5284
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(5879..6508)
                     /locus_tag="GWQ54_RS01495"
     CDS             complement(5879..6508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240524.1"
                     /locus_tag="GWQ54_RS01495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LytR C-terminal domain-containing protein"
                     /protein_id="WP_161244421.1"
                     /transl_table=11
                     /translation="MSMLTPPGMGGKYRIKGDAYPRMRRPRKRGRLVLALVGAVVALGL
                     IGWGTVQLIDVFGGGGGKAKAAAHAKNCPAPAASGSGAPQALPKPAQITVNVYNATPRG
                     GLAKSVADELKKRGFAIGKVGNAPTEYDKKVANNGVLLGAPTAARGPFSVLGTQLAGTT
                     QKTDTRDTPDVDLILGNTFANLNTPKDADTALAALAKPAPAPSGKC"
     misc_feature    complement(6538..6554)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            complement(6622..6918)
                     /locus_tag="GWQ54_RS01500"
     CDS             complement(6622..6918)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949502.1"
                     /locus_tag="GWQ54_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_053725882.1"
                     /transl_table=11
                     /translation="MIFKRIGSGRPYPDHGRESTRQWADVAPRPVRLDQLVTTKGQLDL
                     ETLLAEDSTFYGDLFAHVVKWQGDLYLEDGLHRAVRAALQQRQVLHARVLEMD"
     gene            7015..8718
                     /locus_tag="GWQ54_RS01505"
     CDS             7015..8718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240526.1"
                     /locus_tag="GWQ54_RS01505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helicase HerA-like domain-containing protein"
                     /protein_id="WP_205530604.1"
                     /transl_table=11
                     /translation="MTDSDQTAAAREPISAAEPDETGARNPAPAPADAPAPPVPADAAP
                     VEPAGTAPAVPQPAAEIAAGYGFTGPAMELGALLWDGQCLPDAPIRIPLSMLNRHGLVA
                     GATGTGKTKTLQLIAEQLSANGVPVFLADVKGDVSGISAPGQSGDKVAERAAQVGQEWE
                     AAGFPCEFYGLGGIGPGIPLRATVTSFGPVLLSKVLQLNQTQEQSLGLIFHYADTKGLE
                     LYDLKDLKAVVGFLVSDIGKAELKGIGGLSSVTAGVILRAITAFEQQGAEAFFGEPEFD
                     TSELLRLAPDGRGLVSVLELPAVQDKPHLFSTFLMWLLADLFQKLPEVGDVDRPKLVFF
                     FDEAHLLFNGASKAFLESITQTVRLIRSKGVGIFFVTQTPKDVPADVLAQLGNRVQHAL
                     RAFTPDDAKALKATVRTFPHSPYDLEEVLTSLGTGEAVITVLSENGAPTPVAATRLRAP
                     QSLMAPIDPGALDQAVKSSILYARYAEPVDRESAFEKLSAAERAREEAAVSAALDPSAG
                     SGKPAGRGKKQDASLAEQVVSSGIFRSLARSVGTQLGREISRSIFGTRRR"
     gene            complement(9069..9650)
                     /locus_tag="GWQ54_RS01510"
     CDS             complement(9069..9650)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315302.1"
                     /locus_tag="GWQ54_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HhH-GPD-type base excision DNA repair protein"
                     /protein_id="WP_167158284.1"
                     /transl_table=11
                     /translation="MNTTLRLAQQPEADELLGRSPLAALVGMLLDQQVPMEWAFSGPYT
                     IARRMGADDLDAGAIAAYDPEAFAELLKEKPAVHRYPGSMAKRIQQLCGFLVEEYGGDA
                     AGVWTGVASGAELFSRLKALPGFGEQKARIFLALLGKQLGVRPRGWREAAGPYGEAGSF
                     RSVADITGPESLAKVRAYKQEAKAAARAAK"
     gene            10001..12469
                     /locus_tag="GWQ54_RS01515"
     CDS             10001..12469
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981792.1"
                     /locus_tag="GWQ54_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_240361576.1"
                     /sec_met_domain="T1TS (E-value: 9.5e-83, bitscore: 277.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPFVLPDFYLPYPARLNPHLDSAREHSRTWARDMGMLEGSGIW
                     DLADLDAHDYALLCSYTHPDCDAEQLALVTDWYVWVFFFDDHFLEMFKRTLDRKGGKEY
                     LDRLPAFMPMDLADGFPEATNPVEAGLADLWARTVPSMTKEWRERFAISTRNLLNESLW
                     ELANINAGRIANPVEYIEMRRKVGGAPWSAGLIEYAANAELPASVAGSRPLRVLTDAFS
                     DAVHLRNDLFSYQREVEDEGELSNGVLVLETFLGCTTQQAAEAVNDLLTSRLQQFENTA
                     LTEVPALCLEKGLTPDQCAAVAAYVKGLQDWQSGGHEWHMRSSRYMNEGAALGPSLSDG
                     VLGTSALDVSALFGRPAEARHRSFTHVPRQKVGPSLLPDFDVPYPLTISPHVDHARVES
                     MAWADRMGLLDDIWDAEKLAGYDFALCSAGLDPDATPDELALSAEWLTWGTYGDDYYPL
                     VYGRPRNLAGARAATERFSACMPVDVPAAGALAAVTPMERGLADLWARTAGPMSVEART
                     AFRRSVDVMLESWLWELHNQGQHRIPDPVDYIEMRRYTFGSDLTMSLSRLRHAGQLPPG
                     LYESGPIRSLENAAADYCCLLNDVFSYQKEIEYEGEVHNGVLVVQNFFDCDYPTALRIV
                     DDLMRSRLRQFQHVIDNELPLLVEDFELDQSGRETLGAYVAELQDWIAGILNWHASVRR
                     YGAADLPGSLPHGSSPHTASRGGVAPGWMRPSGDGTSADRVRLPEAWKAAVTATAPPAS
                     TPSVTSGPSATSVSPASTVPSATPVTSVLPVPSVPAGLLVPTVAVPSLPVSAEWSPTLP
                     ASTVAGGHAS"
     gene            12529..13452
                     /locus_tag="GWQ54_RS01520"
     CDS             12529..13452
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742880.1"
                     /locus_tag="GWQ54_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_167158282.1"
                     /transl_table=11
                     /translation="MGHDHGAPSAASGTLSGTYRNRLLWTIGISASITLIQVVGALLSG
                     SLALLADAAHSLTDAVGVSLALGAITLAQRAPTPRRTFGFYRVEIFSAVLNALLLAAIF
                     VWVLYSAIRRFSEPVEVKGGLMFAVAVGGLAANLVGLWLLKDAKDKSLNLRGAYLEVLG
                     DALGSVAVIVGGLIILFTGWQAADPIASIVIGLLIVPRTYGLLRDALHVLMEAAPNDVD
                     LAEVRRHLLEEPGVVDVHDLHGWTVTSGMPVLTAHVVVKETALEGGYGELLTRLQSCVG
                     DHFDVAHSTIQLEPEGHTEAADSLHR"
     gene            13558..15105
                     /locus_tag="GWQ54_RS01525"
     CDS             13558..15105
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (106-341). E-value: 1e-18.
                     Score: 59.8. Matches aSDomain:
                     nrpspksdomains_GWQ54_RS01525_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="GWQ54_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_167158280.1"
                     /sec_met_domain="PF00561 (E-value: 5.6e-27, bitscore: 93.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGESKLARRAIAAGAGAALALAGPATVTRADGPGPDLGRFYEQK
                     IGWEPCEPTEGQTGELLDSVRDMECSTLSVPVDYADPGKGAIALALARIRSAAHGDERK
                     GSVVFNFGGPGESGVDGLAAFRDLAAGIDKHYDLVSFDPRGVARSSPVRCGGEDEAGQL
                     DGEGQDAPGTGAAAVAEAQRVARACHAKTGPVLDHVGTINTSRDMDVLRAVLGDNKLNY
                     LGISYGTRLGAVYASQFPKRTGRMVLDAVDTLRGTAEQDALAQTRGFQQALEAFFAGCA
                     QQNCELGTSPQQVAATFDRAVAKLAGGKTVTGSDNQDFTGDDLHSAVQSALYSQASWPT
                     LSAGIAALLDDDDPTVLAALNPGAGTDDAPASNSDEAMLAINCADDPVRPADPAKAYDS
                     VQRQLTAESPYFGPGSAARAVACAGWPAGTDYIRRIDRPGAPKILVVGGKGDPATPYPW
                     ARDTARQLGSGVLLTYEGEGHGAYAASQCVRAKADAFFATGKVPPEGTSCPAEEPDE"
     aSDomain        13876..14580
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GWQ54_RS01525_Abhydrolase_1.1"
                     /evalue="1.00E-18"
                     /label="GWQ54_RS01525_Abhydrolase_1.1"
                     /locus_tag="GWQ54_RS01525"
                     /protein_end="341"
                     /protein_start="106"
                     /score="59.8"
                     /tool="antismash"
                     /translation="VVFNFGGPGESGVDGLAAFRDLAAGIDKHYDLVSFDPRGVARSSP
                     VRCGGEDEAGQLDGEGQDAPGTGAAAVAEAQRVARACHAKTGPVLDHVGTINTSRDMDV
                     LRAVLGDNKLNYLGISYGTRLGAVYASQFPKRTGRMVLDAVDTLRGTAEQDALAQTRGF
                     QQALEAFFAGCAQQNCELGTSPQQVAATFDRAVAKLAGGKTVTGSDNQDFTGDDLHSAV
                     QSALYSQASWPTL"
     gene            15326..15877
                     /locus_tag="GWQ54_RS01530"
     CDS             15326..15877
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471155.1"
                     /locus_tag="GWQ54_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyltransferase"
                     /protein_id="WP_240361577.1"
                     /transl_table=11
                     /translation="MSSGSVSPEPSSPSATDWRTRPETPADIAAVRAVNLAAFPTASEA
                     DLVDALRADEAWIPGLSIVTVAPDGSVAGHALFTRCRVDGAPALALAPVAVTPEHQRTG
                     AGSAAVRAALGAARELGEDLVLVLGHPDYYPRFGFARASALGIRAPFEVPDEALMALRL
                     RPEGASAPTGVIQYAAPFGV"
     gene            complement(15997..17241)
                     /locus_tag="GWQ54_RS01535"
     CDS             complement(15997..17241)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167158278.1"
                     /transl_table=11
                     /translation="MNAPTAPARHRSPALGRTAIGIVLGLVAGWLLLVTVPHALDVERA
                     FTAAGDCPVAEVSTECRHTISATVTSTAADHQHRSTYYWLGLGHAQNGPVALPGRLKAS
                     PHARGPGRAAAAVPRRIKMDGRTPVFALVRPGAALQLTYWRGEIRYVEYRSLRQYTTAD
                     PRGGYRLPLAAALFLFSVGVACLRGAYCSARRATGVPGAAGSIEVSGSAGSAGSAGSAG
                     SAGAGSQEPWRITLPLASVLLISCFAFGTPWVTGGVPTAVLLTTVGAVPVLAGSAWVTH
                     RRRRRTTDTIKVAPLAPFVEECFPGTIRGEVPYSQEGFGYLVAAPGLLASTPDPFGRLA
                     RCPVPRTLTAVRVRPPYWTDPGPRPAPGSQVVECRDGPTPVYVVTEHCYSAWVLGALRR
                     PADSQFRAGGTARRP"
     misc_feature    complement(17341..17356)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.5"
                     /tool="antismash"
     misc_feature    17656..17669
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            17810..18328
                     /locus_tag="GWQ54_RS01540"
     CDS             17810..18328
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062235.1"
                     /locus_tag="GWQ54_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_167158276.1"
                     /transl_table=11
                     /translation="MSADMKVLLVDDHEDNLFAMESILAPLGYPLELATSGDAALKAAL
                     HGGIAVAVLDVVMPGVSGLDVARYLSRLTQTQLIPVILVTGMGQDSELAAQALHLGVAD
                     YLIKPLDPWALRIKVQYLYRASPLLTAAPRQRGPRNHPAEPAQLPARRRQLHPPETIRV
                     PRRPDEPPR"
     misc_feature    18152..18154
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18381..21278)
                     /locus_tag="GWQ54_RS01545"
     CDS             complement(18381..21278)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GWQ54_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_205530605.1"
                     /transl_table=11
                     /translation="MASGVVSSVALIVAVVASLAGQTGTAAAAAVPVPAASPVSAAPSG
                     KAPAAQDRSEARPASEAATGKVVRPGATPQKDTAQKDKAGQQHAAAARQIGRSGTPDVC
                     SGALAPDTVYTCAQWPAQGASFTVALARPNDVVLVQVVSTDNQAEHPKLTAPDGSAASC
                     EQPDGYGPARCRTATAGTYTLSFTDAFGSGGFSVAYTTLLSGTSCTKVAAANTSLAAPK
                     TFDGTLAAGSAGRCYTLPMADGDVLRAHVSTGQVTTTVYDSTGAQVCSTRQTGSADIDC
                     ALKGTAPFRVQLNQPYATGVTYGLTTARLSKPAGCPVVQPQAYGTVPGTGSTTRCRTLR
                     VPATGPYLFSPIGTASAVSGRLYRPDGTTVCPATPTEPCTLEAGDYVWARDAGDASDAF
                     GIAFHATDQTKGCTAARDDGFASGPATGTFKGAGQQLCRTLATATGEGLYLVDSPPADG
                     ADPDVTVFDAKGVQQCGSDYDFGVCRLTGTAPFHAVLAGPAKGAYRVTIHRTGDATGCT
                     TWAQTPFGRSPGTEVALTAEHRTSCLAIGAGDHSAAEMFDYTNTANRVNASVRVYDGAG
                     NAVCGTSVSSTTTCAFRPGVAYTAALVGTGGPDTYHLVRRDISPTATCAAPQSLAVGGT
                     STGLTFGSALDSGCVRVEGASTDKFWFGVRTPTAAWGTGAELGVADASGTIVCMTQSGS
                     SCRATGSTSYVVFATALGYTDAPIDAHLDTWRIGTAAGWAPECTANSVSPDGFSVRGGV
                     FTESATAYCAVVTMKPSQRFSVYGADNSTTGTPSVSLLSNTRFGGTGTDYAYQCFGNNV
                     GDFSFDCLTGSSAEAGEYVMVVSAGSASTPVEYTMQGVCQQGCSSYPKAPDVSSVSPAS
                     GPAGTQQVVLHGTDLTLGTPVQLASNGSSASPYSMSRAVSVSPDGTSLTVLLTTQDVAP
                     GVYDVVVGGPGYTVGTRSPGYLPGAYTVTAAAPAA"
     misc_feature    complement(21401..21416)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.9"
                     /tool="antismash"
     tRNA            complement(21722..21809)
                     /anticodon=(pos:complement(340370..340372),aa:Ser,seq:gga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="GWQ54_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Ser"
     gene            complement(21722..21809)
                     /locus_tag="GWQ54_RS01550"
     ncRNA           21882..21976
                     /db_xref="RFAM:RF00169"
                     /gene="ffs"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="GWQ54_RS01555"
                     /ncRNA_class="SRP_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="signal recognition particle sRNA small type"
     gene            21882..21976
                     /gene="ffs"
                     /locus_tag="GWQ54_RS01555"
     misc_feature    21975..21984
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
ORIGIN
        1 caccgtataa ccacgtgttg agggcaagtt ggggcagatg gccctgttcg gaggcgcccc
       61 ggggacgaaa aagccccgca cctctcgggt gcggggccgg gcgccgcgta ccggaaggga
      121 gcccggaacg cgtgcggggt cagaacgggt agtcggcgat cacccaggtg gcgaactcgc
      181 gccactggcc ggccgccgcc tggtgcgcgg ggtgctcgac gtatcgcttc agcgcgtccg
      241 cgtcggcgac ggcggagttg atcgcgaagt cgtacgcgat cggccggtcg gtgatgttcc
      301 aggcgcactc ccagaactcg atctcgggaa cgagcccgtc gagctcctgg aaggccttca
      361 caccggcgac cacgcgctcg tcgtcgcgct gcacgccctc gttgagcttg aacaggacca
      421 ggtggcggat catgcatctc tcctacgaat acgacgggaa ccggcccggg cgcggccgag
      481 gactcgtcca cggacgcgtc cgtggacgcg accggcgacg cggccggggg ctcagcgaat
      541 caggttggtc atgaactcgc cgacgccctt ggccgcgctg gatatgccct cgaagccggt
      601 ctggaccatc cctgcggcct gcaccggcga cgtgatgatc gtgtacagca cgaagaccac
      661 ggcgatgtag agcaggacct tcttgatgtc cactgtgcca gcccctcccc ggcgccaccc
      721 ctgtgcggtc gggtgagtct aaccgccccc ggtcccgtac tcaccaggcc tttagggacc
      781 taggacctga cgatcggggc cctttgcccg acggtacgga cgtgacggga gagcaggatg
      841 gttcctgagc ccaccacatc tggcaggaat gcggtgggtg aggaacagga cctcactgcg
      901 gggtccgcgc cgcgagcttc ccccctgact gcggcgcagg gcttgcaggt tctgttctca
      961 tcggggggag cggcttgtcc ccccgatgcc gctccccccg tcctatcgtc gaagccccgg
     1021 tcacttcccc gaccggggct tcttcggtcc ctccgcaggt gaccgcccgc ggaagggccc
     1081 ggcgcggagg ggccgcctcc ggccaatgtc ggccgcgggg gagccacggg gagagcccgg
     1141 gagtaggttc aaagggcact cggggacatc gatcacgatg ctgcttttgt gggacggccg
     1201 ccgcccggtc acggtcgggc gtggcggcgg ccgtccgcgc gaggaggtgg gctcccctcc
     1261 gcactctcct cgcgtcaacc gtcctcggcg gcgcccggag gcctgcggga gactggcccc
     1321 ggctcgaagc gcgccgcgag gacgaagggc cggagccgcg cactgccgag agcggctccg
     1381 gccgccccgt cgacggggcg gacagtgagc gcagacccgg gggcaggggg ccgaggggca
     1441 gccgcccgaa ccggtcgtgc acggttcgag ggcgtccgcc cttgcgttca ctgggcatcc
     1501 taggccgggc cgagggcggc gcaagcgtgg gatttcagcc ggtgaccggc tgtcggaagc
     1561 ggccgccgtc gctcagctcc ggggcagggg ctgggggatc gtcgcggtgt cgaaggtgcc
     1621 gtcgatgatc gcggcggcga agtcggccag tcgcaggtga tggctgcgcg cgtagccgcg
     1681 gaaggcggag aacgcctcgt ccggtgaggt tccccagcgc tcacagagga tgcccttgac
     1741 ctgttccacc aggatgcggc tgttgagcgc ggtctggagc tgggtccgct cgatgtggga
     1801 ctgctccagg gtgcgctgct ggaggatggt gatcgtggcg acgccggcca gggccttggc
     1861 cagggcgatc tcgctctcgc cgaggaggtg gggggtcttc tggaagaggt tgagcgcgcc
     1921 gatgttgcgg tcgcgcagcc gtagcgggat cgcgtgcgtg gctacgtacc cggtctcgcg
     1981 ggcccgggcc gcgaatcggg gccaactcgc cgttgcccca cggctgttga ggtcgatgtt
     2041 cgtccgggcg gtgccgctgc ggtagcactc cacgcacggg ccctggtcgt gctggagggc
     2101 gaacagctcc agaagccggg tgtgctcgtc cgaggcggcc accatctgca gttcgccgac
     2161 cgcgtcggcg agcaggatgc ccgcggcgga cacgtcgagg agctcgacgc accgggtcga
     2221 caggcgctgg agcaggtcca gcacgtcgaa gtcgtccgtc agggagtcgg cgacctccat
     2281 gaagatctcc gccagacgtt gttcgcggat catgtcgatc atccctttcg gccgccgagc
     2341 tcgggcggcc cgtccatatc gtcgttgaac cgcagccgtc tggccaccac gtcctcggct
     2401 acgtcgccga gcggcaggtc ccgggcatag gcgaacgccc gcagccgcgg cagggcgtcg
     2461 gccaaggaga cgtccagctg cacgctgacc atgccggtcg cctggtgcac caccgcccgg
     2521 tgcaactccc ggggcactcc cgtgaccgac ccggaaacgg caggtccgtc cccgcccccg
     2581 tcgtgctcca ggagcagtcc ggtcagtgcc gcggccaagg ccagggcgtc ggcgtaccgc
     2641 tgctccggga cggtgtcgtc ggcccggccc gtcacggcgg tgagcacccc gagccggatc
     2701 gcgccgagtc ccagggggaa gcagtacgcg ccggccacgc cgagtccgag cgcctcggcc
     2761 ggcagaccgg gccagcggtc ggcgcgtacc gccgccaggt ccggtacgac gacggccgtg
     2821 ccgctgtgcg cggcgtccag agtggggccc gtgccgagcg tgaactgcag ctcctcgaag
     2881 tccgccgcga tgccgggcga gtgccacagc ggctccggct ccgcgtcccg gcccgccccg
     2941 acgagcagcg atacggcgac accgtcgacc tgcagcgctc gcgcgcaggc ggcagccagg
     3001 acaccgcagt caccgtgacg gagcgaccgg agcacgtcgg ccatgccgtc gctgatcact
     3061 gggctccacc tgtcgggctc ggggcgatct gcccaccggc tctcgcctgg aagcctatcc
     3121 acgcccgtgg gacgccgccg tcggccggag cggtccggcc gatacccgtc cgtgtcggcc
     3181 cggcgtcggt gccgggcccg gcgtcggtgc cgggcccggc ccaccggctc cgggcacgtt
     3241 ccgcgggagg gccccggtgc gggcatgaag ggggcggtgg gcaagtcgct tgtggcgtag
     3301 gggccttgat ggtcccagga gggctccggc aagggcgtgg tcgggctcgg ggaggtcgga
     3361 atgccgggcg ctccggccgc ccggcgtacc cggcggccct gctcttttgg cgcaatccgg
     3421 tggttccggg caacacggcg acgactcggc gccggggtcg cggcccgcgc cggggcggaa
     3481 cagcacgaag ggcccggttc gaaatgaacc gggcccttcg tactgctggc ggtagcggag
     3541 ggatttgaac cctcggtgag tttccccaca ctcgctttcg aggcgagctc cttcggccgc
     3601 tcggacacgc taccgagaga gagcttagcc caaggtgggc cgtggtttga aatcggttcg
     3661 gcgagagctg ggtcaccgtt gccggaagaa cgccgtgagc tgcgccgaac actcctcttc
     3721 cagcacgccc gcgaccactt cggggcggtg gttgaggcgc tggtcgcgga ccaggtccca
     3781 cagcgaaccg gcggcgcccg ccttctcgtc gcgggccccg tacacgaccc ggtcgatgcg
     3841 ggactggacg atcgcgcccg cgcacatcac gcacggctcc agggtgacga cgagcgtgca
     3901 gccggtcagc cgccactcac cggtctcccg ggccgcgcgc cggatggcga ggacctccgc
     3961 gtgcgcggtc ggatcgccgg tcgcctcgcg ttcgttgtgc ccggacgcca ggaacgtgcc
     4021 gtccggggcc agcacgaccg cgccgaccgg cacatcgccg gccgattcgg cctgtgcggc
     4081 cccggcaagg gcggagcgca tcggctccgc ccaccgttcg cgtacggggt cgtgcgggtg
     4141 gggcactagc ggacggcctc caggacctcg gccgcgccca gcgcgtccgc gatcgtcacg
     4201 agggcgtccc cgtcgagcgc gagcagccgg ccctcgctca cgccgaggtc ggcgaggatc
     4261 gcgctctcgc cgagcggccc ggccggcacg gcgccgtccg acggttcgtc accgtccggc
     4321 ccgtccacgg ccgtcgccgc ctcgtcctcg tagccgtcct ccgtgccgtc gaggtcaagg
     4381 gtgtccagct cgtcctcctc gtcgtcctgg tcgtggccga gcagttcgtc ggtgagcatg
     4441 gccccgtacg aggagcgggc tgcgacggcg gcgttggaga cgaagacgcg cgggtcctcc
     4501 tcgccgtcga cgcggacgac gccgaaccag gcgtcctcct gctcgatgaa gacgagcacc
     4561 gtgtcgtcgg ccccgtcggc ggctgcttca cgggccaggt cggccagatc ggacagcgtc
     4621 tccacatcgt cgagctctgt gtcgctcgct tcccacccgt cttcggtgcg cgcgagcagt
     4681 gcggcgaagt acaccgtgac tctcccactg gtcataggcg tgccggttgg gggtcccccc
     4741 ggctgtggct tcattcggaa tcgtggcaga aaacaccgcg gttgcgagag ttcttccgcg
     4801 gttgcgtttt tccggtcgcc ccgatcacgg cttccgacgc gtcatgatcg cgggctccgg
     4861 gccaccccgt cagaggctcc cgatggccgt gagcacgggc ttcggggcgc cgggttcgcg
     4921 ggtcaccagc ggaaggttcg catgcgcatg gcctggcgca tacgggccgc gcgggcgcgc
     4981 cggggctgga cccggtcgcg caacgccttc gcctcgtgca gttcgcgcag gaactgggcg
     5041 cgccgtcgcc gccggtccgc atcgctctcc ggttgttgcg ctcggtcgcg ctcgtccggc
     5101 attggctcac accgccccgg gtcggttcgt gtcttccacc ttccccccgt tcgggcgctt
     5161 gacgccagcc tgaaccaaca gcaggtggga cgcgggtccc ctacgccccg gttactgtgg
     5221 acgtcatgcg gatccatgtc gtcgaccacc ctctcgtggc gcacaagctc accacgctgc
     5281 gcgacaagcg caccgactcc ccgaccttcc ggcggctcgc cgacgagctg gtcaccctgc
     5341 tcgcctacga agccacccgg gacgtgcgca ccgagcaggt ggacatcgag accccggtga
     5401 cgccgacgac gggcgtgaag ctctcgtacc cgcgtcccct ggtggtcccg atcctgcggg
     5461 ccggtctcgg catgctcgac ggcatggtgc gcctgctgcc gaccgccgag gtgggcttcc
     5521 tcggcatgat ccgcaacgag gagaccctgg aggcctccac ctacgcgacg cggatgcccg
     5581 aggacctctc gggccgtcag gtgtacgtcc tcgaccccat gctggcgacc ggcggcacgc
     5641 tcgtcgcggc gatccgcgag ctgatcaagc gcggcgccga cgacgtcacg gccgtggtgc
     5701 tgctcgccgc ccccgagggc gtcgaggtca tggagcgcga gctggcgggc acgccggtga
     5761 ccgtggtgac cgcctcggtc gacgagcgcc tcaacgagca cggctacatc gtgccgggcc
     5821 tgggcgacgc gggcgaccgg atgtacggca ccgtcgacta gggcttcgcg aaggtttctc
     5881 agcacttccc ggagggcgcg ggtgcgggct tggccagggc ggccagggcc gtgtccgcgt
     5941 ccttcggcgt gttcaggttc gcgaacgtgt tccccaggat gaggtcgacg tccggcgtgt
     6001 cgcgcgtgtc ggtcttctgc gtggtgcccg cgagctgggt gccgagtacg gagaaggggc
     6061 cgcgggccgc cgtcggcgcg ccgagcagca cgccgttgtt ggcgaccttc ttgtcgtact
     6121 cggtgggcgc gttgccgacc ttgccgatcg cgaagccgcg cttcttcagc tcgtcggcga
     6181 ccgacttggc gaggccgccg cgcggggtcg cgttgtagac gttgacggtg atctgcgcgg
     6241 gcttcggcag cgcctggggc gcaccggagc cggacgcggc gggcgccggg cagttcttgg
     6301 cgtgtgcggc ggccttggcc ttgccgccac cgccgccgaa cacgtcgatg agctggactg
     6361 tcccccagcc gatcaggccg agggccacga ccgcgccgac cagcgcgagg accagccggc
     6421 cgcgcttgcg gggacgtcgc atccgcgggt aggcgtcacc cttgatgcgg tactttccgc
     6481 ccatgccggg gggagtgagc atgctcatag gcgcagggta gtgccgaccc gggacgatgc
     6541 ctactaaatg atcaaccgct ggcgtgcgtg tgcgcccgta tgcgccgcaa aaggtccgaa
     6601 aggctcaccc ggctgtcggg ttcagtccat ttcgagtacg cgcgcgtgca gaacctggcg
     6661 ctgctggagc gcggcgcgta ccgcacggtg gagcccgtcc tccaggtaga ggtcgccctg
     6721 ccacttcacg acgtgcgcga agaggtcgcc gtagaacgtg gagtcctcgg cgaggagggt
     6781 ctcgaggtcg agctggccct tggtggtcac gagctgatcg agccggaccg ggcgcggcgc
     6841 gacatccgcc cactgccggg tgctttcccg gccgtggtcg gggtagggcc gcccgcttcc
     6901 gatgcgcttg aagatcacac ggaaagccta ccgggcgagc ggctccgggc gcagccatgg
     6961 agcccgagtg caatcctggg caaaacgcca aaaacccgac gcagggggct cgtcatgacc
     7021 gacagcgacc agacggcggc cgcgcgcgag cccatcagtg ccgcggagcc ggacgaaacc
     7081 ggagcgcgga atcccgcccc cgcgcccgcc gacgcgcccg cgccccccgt gcccgccgat
     7141 gccgcccccg tcgagcccgc cgggaccgcc cccgccgtgc cgcagccggc cgccgagatc
     7201 gccgccggat acggcttcac gggccccgcg atggaactgg gcgcgctgct gtgggacggc
     7261 cagtgcctgc cggacgcgcc catccgcatc cccctctcca tgctcaaccg gcacggcctg
     7321 gtcgccgggg ccaccggcac cggcaagacc aagaccctcc agctcatcgc cgagcagctc
     7381 tccgccaacg gagtgccggt gttcctcgcg gacgtcaagg gcgacgtctc cggcatctcg
     7441 gccccgggcc agtcgggcga caaggtggcc gaacgggccg cacaggtcgg ccaggagtgg
     7501 gaggcggccg gattcccctg cgagttctac ggtctcggcg gcatcggccc cggcatcccg
     7561 ctgcgcgcca cggtcaccag cttcggaccc gtactcctgt cgaaggtgct ccagctcaac
     7621 cagacccagg agcagtcgct cggcctgatc ttccactacg cggacacgaa gggcctggag
     7681 ctctacgacc tgaaggacct gaaggcggtc gtcggcttcc tggtctcgga catcggcaag
     7741 gccgaactca agggaatcgg cggcctgtcg tccgtcaccg ccggggtgat cctgcgggcg
     7801 atcaccgcgt tcgaacagca gggtgccgag gcgttcttcg gggagccgga gttcgacaca
     7861 agcgagctgc tccggctcgc accggacggc cgcggcctgg tgtcggtgct cgaactgccc
     7921 gccgtccagg acaagcccca cctcttctcg accttcctga tgtggctgct cgccgacctc
     7981 ttccagaaac tccccgaggt cggggacgtg gaccggccca agctcgtctt cttcttcgac
     8041 gaggcgcacc tcctgttcaa cggcgcgtcc aaggcgttcc tggagtcgat cacgcagacg
     8101 gtccggctga tccgctccaa gggcgtgggc atcttcttcg tgacccagac cccgaaggac
     8161 gtccccgccg acgtcctggc ccagctcggc aaccgcgtcc agcacgcgct gcgggccttc
     8221 acgccggacg acgcgaaggc gttgaaggcg acggtacgga cgttcccgca ctccccctac
     8281 gacctcgaag aggtcctgac ctcgctcggc accggcgagg cggtcatcac cgtgctgagc
     8341 gagaacggcg cccccacccc ggtcgcggcg acccgtctgc gcgccccgca gtccctgatg
     8401 gcgcccatcg accccggcgc cctcgaccag gccgtcaagt cctcgatcct gtacgcccgt
     8461 tacgccgagc cggtcgaccg cgaatccgcc ttcgagaagc tgtcggcggc ggagcgggcg
     8521 cgggaggagg cggcggtgtc ggcggcgctc gacccgtccg cgggctcggg caagccggcc
     8581 ggccgcggga agaagcagga cgcctcgctg gcggagcagg tggtgagcag cggcatcttc
     8641 cgctcgctgg cccggtccgt ggggacgcag ctgggccgcg agatctcccg ctcgatcttc
     8701 ggcacgcgcc gcaggtaacg cgcgggccgg cccctggggg cgccgccgga cgccgttcgc
     8761 gccttgaggg cgctcgtccg cgaactcccc cacggctttt acggcccagg ggagacgccc
     8821 atgacgggcc gaggctgcct ggtgcgggcc ggcgccaagg tcttgagggg cgcgaggaac
     8881 tgcgtgaacg acccctacgg tccgcagccg aaccaaaggg cccggggacg cagcttccgg
     8941 aagcccaccc acccccattc cacccccgga gggttgcggg aaggggaggg gaggagcaag
     9001 accccggagc ctggggcgga accccagggg gttggccccg ccccccggag cgcccaaccg
     9061 gggcggggct acttcgcggc ccgcgccgcc gccttcgcct cctgcttgta cgcccgtacc
     9121 ttcgccaacg actccggccc ggtgatgtcc gcgaccgaac ggaacgaccc ggcctccccg
     9181 tagggacccg ccgcctcccg ccacccccgg ggccgcaccc cgagctgctt ccccaggagc
     9241 gcgaggaaga tcctcgcctt ctgctcgccg aaccccggca gcgccttcag ccgtgagaac
     9301 agctcggccc cggacgccac tcccgtccac accccggccg cgtcaccccc gtactcctcc
     9361 acgaggaacc cgcacaactg ctggatccgc ttcgccatgg acccggggta gcggtgcacc
     9421 gccggtttct ccttgagcag ctccgcgaag gcctccgggt cgtacgccgc gatcgccccc
     9481 gcgtcgaggt cgtcggcccc catccgccgg gcgatcgtgt acgggcccga gaacgcccat
     9541 tccatgggca cctgctggtc gagcagcatg ccgacgagcg cggccagcgg gctgcgcccg
     9601 agcagctcgt cggcctcggg ctgctgggcg agccgaaggg ttgtgttcat gcctcgatga
     9661 tcgacggccg acgaccccgg cgcacgcgga caccccccgg gtccccgggg gaacgcggac
     9721 cgacactccc cgccccgaca tccccgcccc gatacggggc gcggctcacg tgcccgcacg
     9781 tgtccatccc acatgtgcgc agcccccatg tgcccaagcc cctgtgcgcg gcccacacaa
     9841 gccgcgcccc cgcgcccttt tcgagtcgac tcacgctttc gtatgacaga cgtacggcac
     9901 tcgaatggcc gaggccgggc cgggtagttc cgaccggacc atcacgtgcg taccgggtac
     9961 gtgcgtagca gccatgtgcg taccaagagg ggcgaccgca gtgagccagc cttttgtcct
    10021 gccggatttc tatctgccgt atccggcccg gctcaatcct cacctggact ccgcgcggga
    10081 gcactcccgt acctgggcac gggacatggg catgctggag ggctccggga tctgggacct
    10141 ggcggacctg gacgcgcacg actacgcgct gctctgttcg tacacccacc ccgactgcga
    10201 cgccgagcag ctcgccctgg tgacggactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggag atgttcaagc gaaccctgga ccgcaagggc ggcaaggaat acctcgaccg
    10321 gctgcccgcc ttcatgccca tggacctcgc cgacgggttc cccgaggcga ccaacccggt
    10381 cgaggcgggc ctcgccgacc tgtgggcgcg cacggttccg tcgatgacga aggaatggcg
    10441 cgagcgcttc gcgatcagca cccgcaacct gctcaacgag tcgctgtggg agctcgccaa
    10501 catcaacgcg ggccggatcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgcgccg tggtcggccg gcctcatcga gtacgccgcg aacgccgaac tccccgcgtc
    10621 cgtcgccggg tcgaggccgc tgcgggtcct caccgacgcc ttctccgacg ccgtccatct
    10681 gcgcaacgac ctgttctcct accagcgcga ggtcgaggac gagggcgaac tcagcaacgg
    10741 cgtactggta cttgagacct tcctcggctg cacgacacag caggccgccg aggccgtcaa
    10801 cgacctgctg acctcgcggc tccagcagtt cgagaacacc gcgctcaccg aagtcccggc
    10861 gctgtgcctg gagaagggcc tcacacccga ccagtgcgcg gcggtcgcgg cgtacgtcaa
    10921 gggcctccag gactggcagt ccggcggtca cgagtggcac atgcgctcca gccgctacat
    10981 gaacgagggc gccgccctcg gcccctcctt gtccgacgga gtgctcggca cctcggcgct
    11041 cgacgtctcc gccctgttcg gccgccccgc cgaggcccgg caccgcagct tcacccatgt
    11101 gccgcggcag aaggtcggcc cgtcgttgct gcccgacttc gacgtgccgt acccactgac
    11161 gatcagcccg catgtggacc acgcacgtgt ggagtcgatg gcctgggcgg accgtatggg
    11221 gctgctcgac gacatctggg acgccgagaa gctggcgggc tacgacttcg ccctctgctc
    11281 ggccgggctc gacccggacg cgacaccgga cgaactcgcc ctcagcgcag agtggttgac
    11341 ctggggaacc tacggtgacg actactaccc gctggtgtac ggcaggccgc gcaacctggc
    11401 cggggcgcgg gcggccaccg agcggttctc cgcgtgcatg ccggtcgacg tgcccgccgc
    11461 gggcgccctg gccgcggtga ccccgatgga gcgcggcctc gccgacctgt gggcgcgcac
    11521 cgccgggccg atgtccgtcg aggcccgcac ggccttccgc cggtccgtcg acgtcatgct
    11581 ggagagctgg ctctgggagc tgcacaacca gggccagcac cgcatccccg accccgtcga
    11641 ctacatcgag atgcgccgct acaccttcgg ctccgacctc accatgagcc tgtcgcgcct
    11701 gcgccacgcg ggccaactgc cgcccggcct ctacgagagc ggcccgatcc gcagcctgga
    11761 gaacgcggcc gccgactact gctgcctgct caacgacgtc ttctcgtacc agaaggagat
    11821 cgagtacgag ggcgaggtgc acaacggcgt cctggtcgtc cagaacttct tcgactgcga
    11881 ctaccccacg gccctgcgca tcgtggacga cctgatgcgc tcgcggctgc gccagttcca
    11941 gcacgtcatc gacaacgaac tcccgctgct ggtcgaggac ttcgagctcg accagagcgg
    12001 acgggagacg ctcggcgcct acgtggccga gctccaggac tggatcgcgg ggattttgaa
    12061 ctggcacgcc tcggtacgcc gctacggggc cgccgacctc ccggggagcc tgccccatgg
    12121 cagctcaccc cataccgcgt cccgaggtgg tgtggccccc gggtggatgc ggcccagcgg
    12181 ggacgggacc tcggcggacc gggtccggct gccggaggcc tggaaggcgg cggtcactgc
    12241 cacggcgccc ccggcatcga ccccctccgt gacctctggt ccctccgcga cctcggtttc
    12301 cccggcgtcg acagtgccct cggcgacccc tgtgacctct gtgctccctg tgccctcggt
    12361 gccggcgggg ctcctggtgc ccacggtggc cgtgccgtcc ctgccggtgt cggccgagtg
    12421 gtcgcccacc cttccggcgt ccacagtggc gggaggccat gcctcgtgat cctctgatgt
    12481 gcgggggcca catcccgggg ccggacccgg ccacgaggag gcgcgcgcat gggacacgac
    12541 cacggcgcgc cctcggcggc atccggcacg ctcagcggca cgtaccgcaa ccggctgctg
    12601 tggaccatcg gcatcagcgc gtcgatcacc ctgatccagg tggtcggcgc gctgctttcc
    12661 ggcagcctcg cgctgctcgc cgacgccgcg cacagcctca ccgacgcggt cggcgtctcc
    12721 ctcgcactcg gcgcgatcac gctcgcccag cgggccccga ccccacgccg caccttcggc
    12781 ttctaccggg tggagatctt ctcggcggtc ctgaacgccc tgctgctcgc cgcgatcttc
    12841 gtctgggtgc tgtactcggc gatccgtcgc ttcagcgaac cggtcgaggt caagggcggc
    12901 ctcatgttcg cggtcgcggt gggcggactc gccgcgaacc tggtgggcct gtggctgctg
    12961 aaggacgcga aggacaagag cctcaacctg cgcggcgcgt atctggaagt gctcggcgac
    13021 gcgctcggct cggtggcggt gatcgtgggc ggcctgatca tcctcttcac gggctggcag
    13081 gccgccgacc cgatcgcctc catcgtcatc ggtctcctga tcgtgccgcg gacgtacggg
    13141 ctgctgcggg acgccctgca cgtgctgatg gaagccgccc cgaacgacgt ggacctcgcc
    13201 gaggtccgcc gccacctcct cgaagagccg ggtgtggtcg acgtacatga cctgcacggt
    13261 tggacggtga cgtccggcat gcctgtgctc accgcacatg tggtggtgaa ggagaccgcc
    13321 ctggaaggtg ggtacgggga gctgctgacc cggctccaga gctgtgtggg ggaccacttc
    13381 gacgtggccc actccacgat ccagctggaa cccgagggcc acaccgaggc cgcggactcc
    13441 ctgcaccgct gaccgccccg ccgtgcggtc accgagcgtg agcagcgctc ggcgcgcggg
    13501 ttcgggcggg gctgtctagc ctgttcgggg ggctgcgctt cctggaaggg tgagtccatg
    13561 aagggtgagt cgaagctcgc tcggcgggcg atagcggccg gtgccggagc ggccctggcc
    13621 ctggccgggc ccgccaccgt cacccgcgcc gacggacccg ggccggacct ggggcggttc
    13681 tacgagcaga agatcggctg ggagccgtgc gagcccaccg agggccagac cggtgaactc
    13741 ctcgactccg tacgggacat ggagtgcagc acgctcagcg tgccggtcga ctacgcggac
    13801 cccggcaagg gcgccatcgc gctcgccctt gcccgcatca ggagcgcggc ccacggcgac
    13861 gagcgcaagg ggtccgtcgt gttcaacttc ggcggccccg gcgaatccgg ggtggacggc
    13921 cttgccgcct tccgggactt ggcggccggc atcgacaagc actacgacct ggtgagcttc
    13981 gacccgcgcg gggtcgcccg cagctccccc gtgcgctgcg gcggcgagga cgaggcgggg
    14041 cagctggacg gcgagggcca ggacgcgccg ggtacggggg ccgccgccgt ggccgaggcg
    14101 cagcgcgtcg cccgggcctg ccacgccaag accggcccgg tgctcgacca cgtgggcacc
    14161 atcaacacct cccgcgacat ggatgtgttg cgcgcggtgc tcggcgacaa caagctcaac
    14221 tacctgggga tctcgtacgg gacccggctc ggtgcggtct acgcgagcca gttcccgaag
    14281 cggacgggcc ggatggtcct ggacgcggtc gacaccctgc gcggcaccgc cgaacaggac
    14341 gcgctcgccc agaccagggg gttccagcag gccctggagg cgttcttcgc cggctgcgcc
    14401 cagcagaact gcgagctcgg caccagcccg cagcaggtcg ccgcgacctt cgaccgggcg
    14461 gtcgccaagc tggccggcgg gaagaccgtg accggctccg acaaccagga cttcaccggc
    14521 gacgacctgc acagcgccgt gcagtccgcc ctctacagcc aggcctcctg gcccaccctg
    14581 tcggccggca tcgccgccct cctcgacgac gacgacccga cagtcctcgc cgcgctcaac
    14641 ccgggcgcgg gcacggacga cgcgcccgcg agcaactccg acgaggcgat gctcgcgatc
    14701 aactgcgcgg acgacccggt gcggccggcc gacccggcga aggcgtacga ctcggtacag
    14761 cgccaactca ccgcggaatc accgtacttc gggcccggtt cggccgcgcg ggcggtcgcc
    14821 tgcgcggggt ggccggccgg aacggactac atccgccgca tcgaccgtcc cggcgcgccc
    14881 aagatcctgg tcgtgggcgg caagggcgac ccggcgacgc cgtacccatg ggcgcgggac
    14941 acggcgcgac agctcgggtc gggtgtgctg ctgacgtacg agggcgaggg gcacggggcg
    15001 tacgccgcct cgcagtgcgt acgggccaag gcggacgcct tcttcgcgac cgggaaggtg
    15061 ccgccggagg gaaccagctg tccggcggag gagccggacg agtaaccgtc cggaccggcg
    15121 cgcccgccca cggccggccg ccggaaattc gctgggccgg gggcggggcg aatggcacga
    15181 tcggtcacat atggatactc agcacatggt ccccgagccc acgtggtccg accccatgtc
    15241 ttcggcgccc acatcgcctg agcccacgtc gtccgacccc gtgtcttcgg ggtccgtatc
    15301 gcctgagccc acgtggtccg cccctgtgtc ctcggggtcc gtatcgcccg agcccagctc
    15361 gcccagcgcc acggactggc gtacccggcc cgagaccccg gcggacatcg cggcggtacg
    15421 ggccgtgaac ctggccgcgt tccccaccgc ctccgaggcg gacctcgtcg acgcgctgcg
    15481 cgccgacgag gcgtggatcc ccgggctctc gatcgtgacg gtggccccgg acggctcggt
    15541 cgcgggccac gccctgttca cccggtgccg ggtggacggc gccccggcgc tggccctcgc
    15601 cccggtggcg gtgactccgg agcaccagcg cacgggcgcg ggttccgccg cggtgcgggc
    15661 ggcgctcggg gccgcgcggg agctgggcga ggacctggtc ctggtgctcg gccacccgga
    15721 ctactacccg cgcttcggat tcgcccgggc ctcggccctg ggcatccggg cccccttcga
    15781 ggtgcccgac gaggccctga tggcgctccg gctgcggccc gagggagctt cggcgccgac
    15841 gggcgtgatc cagtacgcgg cgccgttcgg cgtataggaa cggcccccac atgcgctgcg
    15901 gcggggcgct gcggcggatg tgcgacgacg gatgtgcgac gacggccgag tcgccccggg
    15961 ccgagtcgca actgccgagt cgccccggcc gcccggttac ggccgccgtg ccgtgccgcc
    16021 cgcccggaac tgggagtccg cagggcgcct caaggccccc aacacccagg cgctgtaaca
    16081 gtgttcggtc accacataga ccggggtcgg cccgtcccgg cactccacca cctgcgatcc
    16141 gggtgcgggc cggggccctg gatcggtcca gtacggcggg cggacccgga ccgccgtgag
    16201 ggtgcgcggc acggggcagc gggcgagccg gccgaacggg tcgggagtgg aggcgagcag
    16261 gcccggtgca gcgaccagat agccgaaccc ctcctggctg taagggactt caccgcgaat
    16321 cgtgcccggg aagcactcct cgacgaacgg ggccagcggg gccaccttga tggtgtcggt
    16381 ggtgcggcgc cgacggcggt gcgtcaccca ggcggacccg gcgaggaccg gtaccgcccc
    16441 gaccgtcgtc agcagcacgg cggtcggcac cccgccggtg acccacggcg taccgaaggc
    16501 gaaacacgag atcagcagca ccgaggcgag cggcagggtg atccgccagg gctcctgaga
    16561 gcccgccccg gcggacccgg cggaccctgc ggacccggcg gacccggcag atccggagac
    16621 ctcgatggac ccggccgccc cggggacccc ggtggcacgc cgtgccgagc agtacgcgcc
    16681 gcgcagacag gccacgccca cggagaacag aaagagcgcg gcggccagcg gcagccggta
    16741 tccgccgcgc gggtccgccg tcgtgtactg gcgcaggctc cggtattcga cgtatctgat
    16801 ctccccacgc cagtacgtga gttgaagcgc ggcgccgggc cggaccagag cgaagacggg
    16861 ggtgcggccg tccatcttga tgcggcgcgg gaccgcggcg gcggcccggc ccggcccgcg
    16921 cgcgtgcggg ctggccttca gccgcccggg cagcgccacg ggcccgttct gtgcgtggcc
    16981 gaggcccagc cagtagtacg tggagcggtg ctggtggtcg gccgcggtcg aggtcaccgt
    17041 ggccgagatg gtgtgtctgc actccgtcga gacctcggcg accgggcagt cgcccgccgc
    17101 cgtgaacgcg cgctcgacgt cgagtgcgtg gggcacggtg accaggagca gccagccggc
    17161 gacgagcccg agcacgatgc cgatcgccgt gcggccgagg gcgggcgacc ggtggcgggc
    17221 cggggcggtg ggcgcgttca tcgctcgccg ctcgggggcg cgtgccccgc ggaaggggat
    17281 gacgggatca tcatccggtc atcgtgaacc catccgaacc cgaagtttcc tccgtggaac
    17341 ggtggttcag accattgggc cgtcggcttg gggcccggcg gaatcgatca agcggtggtc
    17401 gccgcgccgg cgcaccccgg cgcggatcgg cccgccgacc tgcgcgggtt cacccatagg
    17461 tgtgagccgg gcgaaacatg ggccactggc atgtgcgcgt aggcactgcg tgccgcgggg
    17521 gagcggcgga gggcggggcg tggacgcggt ccgggccggc ggcaacagac atcgtcgaca
    17581 ccctgatgtt ccggggcgcc cggtgcgaga attcggtcca cacaagccag ccgtcgacta
    17641 tgtgcggacc aacccggcac atgcgttgcc acaggtccat cgaggtccat cgaggtccat
    17701 cgaggtgcat tccccacatg cacaccaccg tggtactccc cgactgcgta cgagccgcca
    17761 tgaacgggca tatgcctatt cggcgctccc gagtgaaggt gatggggcca tgtccgcgga
    17821 catgaaggtg ctactggtcg acgaccacga ggacaacctg ttcgccatgg agagcatcct
    17881 cgcgccgctc ggctacccgc tggagctcgc gaccagcggg gacgccgccc tcaaggccgc
    17941 gctgcacggg gggatagcgg tcgcggtcct cgacgtcgtg atgcccggcg tgagcggcct
    18001 ggacgtcgcc cgctacctga gccgcctcac ccagacccag ctgatccccg tcatcctggt
    18061 gaccgggatg ggccaggaca gtgaactggc cgcccaggca ctgcacttgg gcgtggccga
    18121 ctacctgatc aagccccttg acccctgggc cttacggatc aaggtccagt acctctaccg
    18181 cgccagcccc ctcctcacgg ccgccccgcg gcagcgcggc ccccgcaacc accctgcgga
    18241 accggctcaa ctcccggcac ggcgacgcca gttgcaccca ccggaaacca tccgcgtccc
    18301 gcggcggccg gacgagcccc cgcgctgaga aggccccgcc cgggttcccg gacggggcct
    18361 tcctgtgccg atcgggcggc ttaggccgcg ggagccgcgg cggtgacggt gtaggcgccc
    18421 ggcagatatc ccggtgaccg ggtgccgacc gtgtagccgg gcccgcccac cacgacgtcg
    18481 tagacgcccg gtgccacgtc ctgcgtggtg agcagcacgg tgagagaggt gccgtcgggg
    18541 ctgacggaga cggcccggct catgctgtac gggcttgccg agctgccgtt ggaggcgagt
    18601 tgcaccgggg tgccgagcgt caggtcggtg ccgtgcagca ccacctgctg cgtcccggcc
    18661 gggccgctcg ccgggctcac ggaggacacg tcgggcgcct tggggtagct ggaacagccc
    18721 tgctggcaga ccccctgcat cgtgtactcg accggggtgg acgccgatcc cgcgctcacc
    18781 accatcacgt actcgcccgc ttcggcggag gagccggtca ggcagtcgaa gctgaagtca
    18841 ccgacgttgt tgccgaagca ctggtacgcg tagtcggtgc cggttccgcc gaagcgggtg
    18901 ttgctcagga ggctcaccga cggcgtgccg gtggtgctgt tgtcggcgcc gtagacggag
    18961 aaccgctgcg agggcttcat ggtgacgacg gcgcagtacg ccgtcgccga ctcggtgaag
    19021 acgccgccgc gcacggagaa cccgtcgggc gagaccgaat tggccgtgca ctccggcgcc
    19081 cagcccgccg ccgtaccgat gcgccaggtg tcgagatgcg cgtcgatggg cgcatcggtg
    19141 tatccgagag ccgtggcgaa gacgacgtag gacgtcgacc cggtggcgcg gcaggaagag
    19201 ccgctctgcg tcatgcacac gatcgtgccg gaggcgtcgg ccacacccag ctcggcgccc
    19261 gtgccccagg cggcggtcgg agtgcgcacg ccgaaccaga acttgtccgt cgacgctccc
    19321 tcgacgcgca cgcatccgct gtccagcgcc gagccgaagg tcaacccggt ggacgtgccg
    19381 ccgacggcga gcgactgggg ggcggcgcac gtggccgtcg gggagatgtc ccgccggacc
    19441 aggtggtacg tgtcggggcc gccggtgccg accagcgccg ccgtgtaggc caccccgggc
    19501 cggaacgcac aggtggtcgt ggagctgacg ctcgtcccgc acaccgcgtt gcccgcgccg
    19561 tcgtacaccc gcaccgaggc gttgacccgg ttcgccgtgt tcgtgtagtc gaacatctcg
    19621 gcggcggagt ggtcgccggc gccaatggcc aggcacgacg tccggtgctc cgccgtgagc
    19681 gccacttcgg tgcccggtga acggccgaac ggcgtctgcg cccaggtggt gcagccggtg
    19741 gcgtcgccgg tgcggtggat cgtgacccgg tacgcgccct tggcgggccc ggccagcacc
    19801 gcgtggaagg gcgcggttcc ggtcagccgg cagacgccga agtcgtagtc ggagccgcac
    19861 tgttggacgc ccttggcgtc gaagacggtc acatcggggt ccgcgccgtc ggcgggcggg
    19921 ctgtcgacca ggtagaggcc ttccccggtg gccgtcgcga gagtgcggca gagctgctgg
    19981 ccggcgccct tgaaggtgcc cgtcgcgggc cccgaggcga agccgtcgtc gcgcgcggcg
    20041 gtgcagccct tcgtctggtc cgtggcgtgg aaggcgatgc cgaaggcgtc cgaggcgtcg
    20101 cctgcgtcgc gcgcccagac gtagtcgccg gcctccaggg tgcagggctc ggtcggggtg
    20161 gcggggcaca ccgtcgtgcc gtcgggccgg tagagcctgc cggagacggc ggaggcggtg
    20221 ccgataggcg agaacaggta cggcccggtg gcgggcacgc gcagggtgcg gcagcgcgtc
    20281 gtcgaacccg tgccgggaac cgtgccgtac gcctgcggct gtacgacggg gcagccggcc
    20341 ggcttggaca ggcgagcggt ggtgaggccg taggtgacgc ccgtggcgta cggctggttc
    20401 agctgcacac ggaacggggc ggtgcccttc agcgcgcagt cgatgtcggc actgcccgtc
    20461 tgacgggtgg agcagacctg cgccccggtg ctgtcgtaga ccgtcgtggt cacctgtccc
    20521 gtggacacgt gggctcgcag cacgtccccg tcggccatgg gcagggtgta gcagcggccc
    20581 gccgagccgg cggcgagggt gccgtcgaag gtcttcggtg ccgcgagcga ggtgttggcg
    20641 gcggccacct tggtgcagga ggtgccggag agcagcgtgg tgtacgcgac ggagaagccg
    20701 ccgctgccga aggcgtcggt gaacgacagg gtgtacgtgc cggccgtcgc cgtccggcac
    20761 cgcgccggtc cgtatccgtc gggctgctcg caggaggccg cggagccgtc cggggcggtc
    20821 agcttcgggt gctcggcctg gttgtcggtg gagacgacct ggaccaggac cacgtcgttc
    20881 ggccgcgcca gggcgaccgt gaagctcgcg ccctgcgccg gccactgcgc gcaggtgtac
    20941 acggtgtccg gtgcgagcgc tccggagcag acgtccggcg taccgctccg gccgatctgc
    21001 cgtgcggcgg ccgcgtgctg ctgcccggcc ttgtccttct gcgccgtgtc cttctgtggc
    21061 gtggcgccgg gccggacgac cttgccggtc gcagcctcgg aggccggacg cgcctcggaa
    21121 cggtcctgcg cggccggggc cttcccgctc ggcgcggccg acaccgggct cgcggccggc
    21181 acgggaacgg cggccgccgc cgcggtgccg gtctgtccgg cgagcgaggc gacgacggcg
    21241 acgatcagag ccaccgacga gacgacgccc gaagccacgg gtctctttct ctgccgctcg
    21301 tagcggctgc gcagttgcac catgtggtcc ccccctggga acgaagaact cacccctgtt
    21361 gtgcacagga gtgccgatcg ggcggagtgt aacgagggcg tcggacagcc gttcgacctt
    21421 tttccggccc gcccccaggg ccggcggcgc ggccgccccg gacgcggccg ccccggacat
    21481 ggccgccccg gacgtggccg ccccggacac ggaggagccg gaacacggag gagccggaac
    21541 acggaggggg tcgggaagtt gggagagccg gaacacggag gaggccggga aacaggaagg
    21601 ccgggatctg gggtgagcac ctgggcccgg agaaggcccg accatgggga tgccccggac
    21661 acggagaagg ccccggccgg tttcccggtc ggggccttca acatcgtgcc cggtgaggca
    21721 ctggcggagg atacgagatt cgaactcgtg aggggttgcc cccaacacgc tttccaagcg
    21781 tgcgccctag gccactaggc gaatcctccg cggcaaacaa tacaagacgt tgaggggtgc
    21841 tcgcgaactc gttcccacct cagggatcag gtaccctgtg cggagcccct cacgtggcgc
    21901 tatctgactg aactccccca gggccggaag gcagcaaggg taggtcggct ctggcgggtg
    21961 cgtggggggc gccttatttt gtgcggcgcg ggatgcccgt tccccttgcg ggcggggccg
    22021 gttcggccgg ggggcccggg acgggccgtc gtcggcgggc ccggttgtca gtgggccccg
    22081 ataacctcgt atgcgtgtcg tcccttgcgc tgtaccgccg ctaccgcccc gagtcgttcg
    22141 ccgaggtcat cgggcaggag catgtcactg acccgctgca gcaggcgctg cggaacaacc
    22201 gggtcaatca cgcgtacctg ttcagcgggc cgcggggctg tggcaagacg accagtgctc
    22261 gcatcctggc ccgctgtctg aactgtgagc aggggccgac gcccaccccg tgcggggagt
    22321 gccagtcctg ccgggacctc gcgcgcaacg ggccgggttc catcgacgtg atcgagatcg
    22381 acgcggcttc gcacggtggt gtcgacgacg cccgtgagct gcgcgagaag gccttcttcg
    22441 gccccgcctc cagccgctac aagatctac
//
