LOCUS       NZ_CP036534            22211 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. VN1 chromosome, complete genome.
ACCESSION   NZ_CP036534
VERSION     NZ_CP036534.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. VN1
  ORGANISM  Streptomyces sp. VN1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8341703)
  AUTHORS   Nguyen,H.T., Pokhrel,A.R., Nguyen,C.T., Pham,V.T.T., Dhakal,D.,
            Lim,H.N., Jung,H.J., Kim,T.S., Yamaguchi,T. and Sohng,J.K.
  TITLE     Streptomyces sp. VN1, a producer of diverse metabolites including
            non-natural furan-type anticancer compound
  JOURNAL   Sci Rep 10 (1), 1756 (2020)
   PUBMED   32019976
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8341703)
  AUTHORS   Pokhrel,A.R., Nguyen,H.T., Dhakal,D., Nguyen,C.T., Pham,V.T.T. and
            Sohng,J.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2019) Department of BT-Convergent Pharmaceutical
            Engineering, Institute of Biomolecule Reconstruction, Sunmoon-Ro221,
            Asan, Chungnam 333-708, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: HGAP3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011650445.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 03:53:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,284
            CDSs (total)                      :: 7,197
            Genes (coding)                    :: 7,083
            CDSs (with protein)               :: 7,083
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 44 of 114
            Pseudo Genes (incomplete)         :: 82 of 114
            Pseudo Genes (internal stop)      :: 3 of 114
            Pseudo Genes (multiple problems)  :: 15 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:32:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6392351
            Orig. end                         :: 6414562
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036534.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jae Kyung Sohng.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22211
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22211
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22211
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12211](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12211
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(277..636)
                     /locus_tag="EZV63_RS28270"
                     /old_locus_tag="EZV63_28680"
     CDS             complement(277..636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445342.1"
                     /locus_tag="EZV63_RS28270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28680"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_031043024.1"
                     /transl_table=11
                     /translation="MTGGDAGGRLVRPFTLTGGRTRPSRADFTLITTVTACDPQPDRAA
                     RPQPEHLRILRLCARPVAVAEVAARLDLPVSVVVILLSDLVEADRITARPPHPVNLATP
                     DLDLLQKVRDGLGRL"
     gene            complement(638..1057)
                     /locus_tag="EZV63_RS28275"
                     /old_locus_tag="EZV63_28685"
     CDS             complement(638..1057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326005.1"
                     /locus_tag="EZV63_RS28275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28685"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_003972853.1"
                     /transl_table=11
                     /translation="MTRPSPATHTELDQLLTGLVERVADVNQAVVLSEDGLVVSKSTGF
                     LRDDAERLAATASGLMSLSKGVSMDFRGGPVRQALIEMANSYLILTSAGPGAHLVVLTG
                     PNADVGVVAYQMNMLVKKIGEHLSAAPRATAGPGE"
     gene            complement(1054..3690)
                     /locus_tag="EZV63_RS28280"
                     /old_locus_tag="EZV63_28690"
     CDS             complement(1054..3690)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327592.1"
                     /locus_tag="EZV63_RS28280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28690"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_166625148.1"
                     /transl_table=11
                     /translation="MPARKTRKKGARRRLGSIRLSLILLALVPGVTLAGMWSVTTIQMF
                     SEGLQLRAQTQLSRDTGAMGTEATLALQQERSLSAAWLAAPDGDRTALDEQREKTDAAV
                     AQLVGQSDAIDRAPSRISDRLYSVLGSVTSLEYYRSQVDNPTDITSEQALDQFTSIVDD
                     QIHAFQELSQVDDGDLTSQAGPLVSLEQAAELASQEDARLTLAWPSDRMDDEQWTRFTQ
                     LVHTRRWLVQSQIVPSLSGSAKTQTERILASAEWKSMQDVEDQVLAARTAGGENRIDLP
                     DARQRWVTAFEKIRVQYGQLIRQQTEGLLDRSAGEARGLLIKAGILSAGGLVALLLCVF
                     ISWRITRSLSRRLRGLRLATLGLAEERLPDVVARLERGEKVDVESATPPLDYGHDELGQ
                     VAQAFNTAQRTAVHTAVELADTRRGFQKVILGIARQSQNLVNMQLGKLDALEREHTDPE
                     ILKGLYELDSTASQLRRYEENLVIISGEQPRRTWRDPVSLVDILRSAVGEVAEYQRVEL
                     HADEEVGLAPPAVADVIHLLAELIDNATAYSPAPNPVGVRAALVAKGLAIEIEDRGLGM
                     SEEDYASFNEQLAVAPQFDVVALADDLRLGMFVVARLAHRHGVTVTLRPSPYGGTTAIV
                     LIPYEIVVRDVTGGSGSGDGRGVPAVPTSDMADPAGSARPSVSAAASAASPSSGPSGSP
                     GPSGDFAVTAAVGGAGRTASPAGPTSNGAAPAQRPVRPPRPLPVSRSAPAADSAERGGL
                     APLPRRVPQTSLAAELRDEDLGGRDGRNGSSDDWADFTAERAASSLAGFQRGSLRAQTD
                     DDAHDGTDDGMNGIHFGPDPAGPPAHPDHDAGPTPGDHSDSDGQVFSPAAPSTPPADRR
                     SPTKDSR"
     gene            complement(3756..4769)
                     /locus_tag="EZV63_RS28285"
                     /old_locus_tag="EZV63_28695"
     CDS             complement(3756..4769)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972851.1"
                     /locus_tag="EZV63_RS28285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28695"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_037762826.1"
                     /transl_table=11
                     /translation="MSTSHPSTHSFRPLRAAAFAAAVCLLAAGCSVFGGDEDGSAADAA
                     GGSGSNRMRIVMVTHGDEGDAFWDRVRKGAEAAAAKDGVDLTYAGDADTADQADLVRDA
                     VRDKVDGIAVTLAKTQAMKAPVAEAKAAGIPVVGLNSGMDAWRGTGLLTYFGQDESVAG
                     RAVGDKLNSLKAKHALCVIHERGNVAVEARCAGVKKTFEGETEMLYVEGSDMEAVRTSV
                     TARLKQDNSIDEVVMNGAAFALTAVDSVDEAGSKAKVATFDLSEDLIAAIKRGDIQFAV
                     DQQPYLQGYLSVDALWLYRTNGNVSGGTEAPVLTGPAFVTRENADEVGKYAAGGTR"
     gene            complement(5222..5680)
                     /locus_tag="EZV63_RS28290"
                     /old_locus_tag="EZV63_28700"
     CDS             complement(5222..5680)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326008.1"
                     /locus_tag="EZV63_RS28290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28700"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_166625149.1"
                     /transl_table=11
                     /translation="MPGDRRRGFRAAFRDWRSGRPFWGGLLLALGGAEVLFTMKASFKV
                     VIHVGMQGVAGYLLPVVMLLCGVLALVNPAQRLFYSLIGVLASLGTWITSNLGGFLVGL
                     LLGCVGSCLVFGWLPDQESRRDRRRRRKAARAARTAPPPLEQGAGGTA"
     gene            complement(5680..6330)
                     /locus_tag="EZV63_RS28295"
                     /old_locus_tag="EZV63_28705"
     CDS             complement(5680..6330)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675692.1"
                     /locus_tag="EZV63_RS28295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28705"
                     /product="DUF6230 family protein"
                     /protein_id="WP_166625150.1"
                     /transl_table=11
                     /translation="MAPSPDDTPSAGNTSEHARPGRVRLRRAAVLAVPAAAVTATLAVL
                     TAQGALGVQFAISGMPFTVTATELDGNGFAQFGGLDNMAEGSPNAGDTGGQVLVVTSVI
                     ENAKLTKLCQSVDLGGTNLLITAGDGSTRVSASNLTTDSTFLSGDASFNNIEIGNDAGT
                     LDKAGPKGRGPIGVFSQQADTVHIKNLRQTNYATTAAVFKLPGLKLRFSGSGC"
     misc_feature    complement(6510..6525)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     misc_feature    6624..6644
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            6957..7613
                     /locus_tag="EZV63_RS28300"
                     /old_locus_tag="EZV63_28710"
     CDS             6957..7613
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="EZV63_RS28300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28710"
                     /product="hypothetical protein"
                     /protein_id="WP_037762820.1"
                     /transl_table=11
                     /translation="MRTRTLLTLTAAVAALALPAAVPAAAAADTPVLTTGTAGGTPVAV
                     GDTLTAPLASGTSATFRSSAGGSSGVSCTSSQFTVTVTDNPTAPGTATESLTAHTFDSA
                     SCSSNVTGVLGVTGIQVANLPYTTTVSSEGAVAVTPPSGSTVRTTVSLRTLLGSINCVY
                     EAPGLSGTAANDDNSIAFADQHFTKVSGSGLCFADGYFTATYAPVTDGSATVFVN"
     gene            7820..8467
                     /locus_tag="EZV63_RS28305"
                     /old_locus_tag="EZV63_28715"
     CDS             7820..8467
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030630.1"
                     /locus_tag="EZV63_RS28305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28715"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_166625151.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIVGAAADLFDRRGYESTSLSEIVAHAGVTKGA
                     LYFHFAAKEDLAHAIMEIQSTTSRRLATELAARGYTALESLMRLTFGMARLCEEGPVLR
                     AGLRLAAGGVPVRPPLPHPFTEWREIATSRLLDAVRQSDVHPDIDVASVAHTLVCSIVG
                     TRLVSGALEPAGRQPRRLAEMWHILIRGMVPVTRRARYVTLAARLERETPTA"
     gene            8569..9816
                     /locus_tag="EZV63_RS28310"
                     /old_locus_tag="EZV63_28720"
     CDS             8569..9816
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445377.1"
                     /locus_tag="EZV63_RS28310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28720"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_166625152.1"
                     /transl_table=11
                     /translation="MPATPAESAPVILGDEPGSFPHGVLAERHPAIVRQVRAAFPYGPE
                     VRDALDALLASCADGVVEPVPAGADPTGRDRERWAGWGMDAYAGRSWYDVPWLWAESHF
                     YRRLLDAVGYFGPGVWQGVDPFRPAKLAELDAPETGEELAALDTLADLPAEERIRALLH
                     GSLWGNRADLGFRLSEGGTGTREQVDALVADDSDALWSLLPPAGTGPTGPTGAAGAATP
                     ARPRTLCLVADNAGRELVPDLLLVSHLLAEGRVDRAVLHLKPYPYYVSDATPADLLDAL
                     RRLAAAGGTAAVYGERLWNALADGRVTVRAHPFSCAPLPYAEMPDDLRAEFAAATVTVL
                     KGDLNYRRLVGDRWWPPTTSFADATGYFPGPVAALRTLKSDVVTGLTAGTEAALEASGE
                     RRWRTSGTHALIQVRR"
     gene            10001..12211
                     /gene="cyc2"
                     /locus_tag="EZV63_RS28315"
                     /old_locus_tag="EZV63_28725"
     CDS             10001..12211
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564389.1"
                     /locus_tag="EZV63_RS28315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28725"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_166625153.1"
                     /sec_met_domain="T1TS (E-value: 4.4e-77, bitscore: 259.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQPFELPHFYLPHPARLNPHLDEARAHSTTWAREMGMLEGSGV
                     WEQSDLDAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLEKYKRTQDRLGGKA
                     HLDRLPLFMPLDPTAGMPEPENPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESL
                     WELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGTRPLRVLMETFS
                     DAVHLRNDLFSYQREVEDEGELSNGVLVLETFFDCTTQEAAELVNDVLTSRLHQFEHTA
                     FTEVPAVALEKGLAPSGAAAVAAYTKGLQDWQSGGHEWHLRSSRYMNKGALPTAGWQAL
                     TGPGTSAADVGALLAAAAAGRARPYAWTPFQKVGPSVIPDIRMPYPLELSPALEGARRH
                     LFEWCAEMGILSEGVWDEDKLGSCDLPLCAAGLDPDATQDQLDLASGWLAFGTYGDDYY
                     PLVYGHRRDLAAARLTTARLSACMPLDGEPVPPPANAMERSLIDLWARTTAGMTPEERE
                     PLKTAVDTMTEAWVWELANQIQNRVPDPVDYLEMRRATFGSDLTLGLCRAGHGPSVPPE
                     VYRSGPVRSLENAAIDYACLLNDVFSYQKEIEYEGEIHNAVFVVQNFFGVDYPAALRVV
                     QDLMNQRMRQFEHVVAHELPVVYDDFQLSDEAREIMHGYVTDLQNWMAGILNWHRNVPR
                     YKAEYLAGRTHGFLPDRIPAVPVSASRSVPVSEWGRSPVPTP"
     misc_feature    complement(10005..10020)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            12287..12874
                     /locus_tag="EZV63_RS28320"
                     /old_locus_tag="EZV63_28730"
     CDS             12287..12874
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327594.1"
                     /locus_tag="EZV63_RS28320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28730"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_037762817.1"
                     /transl_table=11
                     /translation="MEQTALRPKPMPGREPGTGTEPAAARRPRPGRRRRRVTTVLLGVL
                     AALVLLLTGVGLGTVGATVVGMSRLAEMQRGPAAQEPGAGASPGTRAAPAHPSAAPSPS
                     PARAGATLGVEAVDDRKPGARIVGVHMPGPGFAAGLVRGDVLLTFGTTRVDSAADLAHA
                     VARARPGKGVRITVRHESGGYQQLTAVPGVVT"
     misc_feature    complement(12991..13004)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            13094..14224
                     /locus_tag="EZV63_RS28325"
                     /old_locus_tag="EZV63_28735"
     CDS             13094..14224
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="EZV63_RS28325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28735"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_166625154.1"
                     /transl_table=11
                     /translation="MTGSHAAASFTADDYRARMDRAARAAAGAGLAGLLVAPGPDLVWL
                     TGYTPPADTERLTLLVLAPDRDPVLVVPALEAPDARNATGASALTLHDWTDGKDPYAAT
                     AALLGASGRFGISDNAWAMHLLALQRTLPGTSYASLTEALPMLRAVKDAAELDLVAAAG
                     AAADEAFEEIRDVRFGGRRESEVAADLAGLLRRFGHSQVDFTIVASGPNGANPHHEVGD
                     RVIEDGDMVVLDFGGLKDGYGSDTSRTVHVGEPTDEERRVHDLVREAQEAGFRAVRPGA
                     ACQDVDRAARAVIAGAGYGEYFIHRTGHGIGVTTHEPPYMIEGEEQPLVPGMCFSVEPG
                     VYLPGRFGVRIEDIVTVTEDGGRRFNGTTRELVVVE"
     gene            14325..15260
                     /locus_tag="EZV63_RS28330"
                     /old_locus_tag="EZV63_28740"
     CDS             14325..15260
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326016.1"
                     /locus_tag="EZV63_RS28330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28740"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_070389414.1"
                     /sec_met_domain="APH (E-value: 6.7e-17, bitscore: 60.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVGSLLGGSTEPDVRPVAAGADPATWWVGPR
                     HVLRLAPDGDAAVRQRRELRLRELVRPRVPVAVPTSVAHGEWAPGLTYTLDARLTGGSG
                     EDHDVSALGEADLAALLTGMREVPGRQAEALGVPRAAPRSLETLRRTAERAARRLAEAD
                     EFDPARPERLTGQAAAQLGAQQGTAVLVHHALAGEHLVVGADGRVRGVLGWTDAVLGDP
                     AEDIAGLALCVGAPAAVRAATLAGYGARPCLRGLWLARCDTVVQLADALHGRSGPPPAA
                     LLRTRLRRAWEPILLERVTELRGDDPDDAP"
     gene            complement(15366..17111)
                     /gene="treZ"
                     /locus_tag="EZV63_RS28335"
                     /old_locus_tag="EZV63_28745"
     CDS             complement(15366..17111)
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034231.1"
                     /locus_tag="EZV63_RS28335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28745"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_070389415.1"
                     /sec_met_domain="Alpha-amylase (E-value: 4.6e-13, bitscore:
                     48.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQAGRVTLECDGVTRTLEQDPERPGWWCGRSEARDGSR
                     YGFAVDDGPVLPDPRSRRQPDGPDGLSAVVDHDRYPWRTPWAGRPLPGGVLYELHVGTF
                     TPPGTLDAAAARLDHLVELGVTHVQLMPLCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNYLPAFGPYFTDTHHTPWGVAVNLDAPGSDEVR
                     AYLVGSALAWLRDYRLDGLRLDAVHALVDTRACHFLEQLSAAVDALAADLGRPLFLIAE
                     SDLNDPRIITPRAEGGLGVHAQWNDDFHHALHTALTGESQGYYADFARDPLAALAKTLT
                     RGYFHDGTWSSFRGRGHGRPLDRARTAAHRLTGYSQTHDQIGNRAQGDRLAALVSPGLA
                     ACAATLTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPELARAVRDGRRREFAAHGWREE
                     DVPDPQDPATRERSCLDWSEPGREPHARVLDWYRRLIALRAGQPDLTDPDLADSRVAYD
                     PAARWLAFRRGDIRVAVNLGPGPAAIPLGNRPARVLAAWEPVTGPGPDGLLHLPGESSV
                     VLVQE"
     gene            17285..17836
                     /locus_tag="EZV63_RS28340"
                     /old_locus_tag="EZV63_28750"
     CDS             17285..17836
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="EZV63_RS28340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28750"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_031043055.1"
                     /transl_table=11
                     /translation="MTSSFEFNTYPARLSDAERDKALKVLRDGAAMGRLSHDTFVRRME
                     LALTARRPEELAVLTADLNTEGRLSRLVFGTVEAVSGFGARLATAWRAERLPKLLLPHP
                     GTGHPLRIGRDPASGLRLSHETVSRVHAELSRQGGMWVLRDLGSTNGTTVNGRRVIGAA
                     VVRDGDQIGFGRMAFRLAGD"
     gene            18038..19363
                     /locus_tag="EZV63_RS28345"
                     /old_locus_tag="EZV63_28755"
     CDS             18038..19363
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445382.1"
                     /locus_tag="EZV63_RS28345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28755"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_051159502.1"
                     /transl_table=11
                     /translation="MDELGARADALVARHPRHARLRRVGTSRAGAPLLLLSVGRGSRQV
                     LVVAGPHANEPVGGATALRLAERAVADLRLTEGADATWNLLLCVDPDGLRRNEGWLSGP
                     YTLGRYARNFFRPGFLEQPEWLPDGPDRAALPETRTLLGLQEELRPFLQCSLHGVDVGG
                     GFVELTHELPGIAGRVSHTAARLGVPRELGAYDTLYWPQLGPAVYRIPPPRRGDFTAAI
                     TEAAVDSTWCHPQRYGTVTAVVEAPMWGVAAVADASPPSDRDAMLRFVSHTLRQDARRL
                     QRLLARIRPHLAAVPGAAHLLAPVDDYLLVCPGLADTWDPDTDDGSGRPLPPMSTAHLV
                     ALRLAGRRLALRTAGLLHQLVTRAGADPEGVLPELDRLVDEGCADYLDGCGARWIPVAR
                     QVEYQTRVVLAAFELAGRRPAEDPRPVEAGRGPGAAVPMHRE"
     gene            complement(19383..21998)
                     /gene="treY"
                     /locus_tag="EZV63_RS28355"
                     /old_locus_tag="EZV63_28765"
     CDS             complement(19383..21998)
                     /EC_number="5.4.99.15"
                     /GO_function="GO:0047470 - (1,4)-alpha-D-glucan
                     1-alpha-D-glucosylmutase activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972839.1"
                     /locus_tag="EZV63_RS28355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_28765"
                     /product="malto-oligosyltrehalose synthase"
                     /protein_id="WP_228773808.1"
                     /sec_met_domain="Alpha-amylase (E-value: 2.2e-14, bitscore:
                     52.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPERPGPVPSPAASPVPSATYRLQLQPDFRFEAAAAAVPYLASL
                     GVSHLHLSPVLEAVPGSRHGYDVVDHARVRAELGGEEGLRALARTAREHGLGLVVDIVP
                     NHMAMSPRHNRALWEVLREGPESPYARWFDIDWRAGGGQVLLPVLGAPVGEVLDDLRAD
                     GGVLRYHEHAFPLRDGTADLPLPQLLDAQWYRPVWWRLARTELNYRRFFSISELIGLRV
                     EDPEVFEATHATVLRLLREGVVDGLRVDHPDGLADPGAYLARLHEATGGRWTVVEKILA
                     DGERLPAAWPVAGTTGYDALRHVDGLFTDPAGYGELLGRYRAFAAPQPDRGGDWAATVR
                     RAAYRVLTHELATELDRLTRLAHRLCAASPQPAPRDRAPWALGTALRELLVRLEVYRPY
                     TAADAGEVVTGEAAAEARLAFTVPEEAGAVDVVRDLVLGRYGDGPDHEEFRARFAQTAS
                     ALRAKSVEDTAFYRYVPLLSATEVGGNPGGPALDPEVFHAYCARVQRDWPATGTVVSTH
                     DTKRSADVRAALAVLTECPARWADVLTEVARAGEGAPDPQLAWAAWQTVFGLGPADGGR
                     VRDALLKHVREAGLHTGWTERVASYEEAVEAFVAAGPCGAPGERVAELRKAVEPHVRAN
                     VLGTALVHLTMPGVPDLYQGTEHEYLALVDPDNRRPVDFPTAHPATGSDGESGERAGGA
                     SGAGGASGAGGAGGAGGASGASGAGGAGGAGGASGAGGAGGAGSTGGAGGAGSTGGAGG
                     AGSTGGAGKTVVTRAALALRARRPGAFGGAATYEPVRAEGPAAEHCVAFARSGDVVTAV
                     TRLSLRLAQEGGWRGTTLPLPPGRWADTLAPGREFTGHARVEELFADTPVALLERVGDQ
                     "
ORIGIN
        1 aacaggtaca gcaccaggtc ccgggtgatg gtgatccgcc cgaagtccag ggccacggtc
       61 gtggcccgct tctcctcgat gccggcgaga tcgtcgatgt cgagtcccgc cgcggtcagc
      121 ggctcctcgg tgcgcagcgg ggcgatctcg ctcaccgacc cgaccatggt ggtcttgccg
      181 acgccgaagc ccccggcgat gaggatcttg acggcatccg gcgcggcgga gcgcgcggtg
      241 gggcgggggg atgccgtggg cgccggagcg gcgcggtcag agccggccaa ggccgtccct
      301 cactttctgc agcaggtcca ggtccggtgt ggcgaggttg accgggtgcg gcggccgggc
      361 cgtgatccgg tccgcctcca ccaggtccga gagcaggatc acgaccacgc tcaccggcag
      421 gtcgaggcgg gccgcgacct ccgccacggc caccggcctg gcgcacagcc gcaggatccg
      481 caggtgctcg ggctgcggac gcgcggcccg gtcgggctgc ggatcgcacg cggtcaccgt
      541 cgtgatgagc gtgaagtcgg cgcggctggg ccgggtccgg ccgccggtca gggtgaacgg
      601 ccgtacgagc cggccccccg cgtcgcctcc ggtcacgtca ctcgccgggg ccggcggtgg
      661 cccgcggtgc cgcgctcagg tgctcgccga tcttcttcac cagcatgttc atctggtacg
      721 ccacgacgcc gacgtcggcg ttcggcccgg tgagcacgac caggtgcgcg ccggggccgg
      781 cggaggtgag gatcaggtag ctgttggcca tctcgatgag cgcctggcgg accgggccgc
      841 cgcggaagtc catgctgacg cccttgctca gactcatcag ccccgaggcg gtcgccgcca
      901 gccgctccgc gtcgtcccgc aggaacccgg tggacttgct gacgaccagt ccgtcctcgg
      961 agagcaccac cgcctggttc acgtcggcga cccgctccac gagtccggtg agcaattgat
     1021 ccagctcggt gtgcgtggcg ggggagggtc gggtcatcgg ctgtccttcg tcggcgatcg
     1081 gcggtcggca gggggagtcg agggggcggc tggggagaac acctggccgt cggagtcgga
     1141 gtggtcgccg ggggtggggc cggcgtcgtg gtcggggtgg gccggaggcc cggcggggtc
     1201 ggggccgaag tggatgccgt tcatgccgtc gtccgtgccg tcgtgcgcgt cgtcgtccgt
     1261 ctgggcccgc agcgagccgc gctggaaacc ggcgagggag gaggcggcgc gctcggccgt
     1321 gaagtcggcc cagtcgtcgg acgaaccgtt cctgccgtcc cggccgccga ggtcctcgtc
     1381 gcgcagttcg gcggcgaggc tggtctgcgg caccctccgg ggcagcggcg ccagaccgcc
     1441 ccgctcggcg gagtcggcgg ccggcgcgga ccggctcacg gggagcggcc gcggcggccg
     1501 tacgggccgt tgcgcgggag cggcgccgtt cgacgtcggc ccggcgggcg aggccgtccg
     1561 tccggctccg ccgactgccg cggtcacggc gaagtcaccg gaggggccgg gggagccgga
     1621 gggacccgaa gacggggaag cggcggaggc ggcggcggag acggacgggc gggccgagcc
     1681 tgccgggtcc gccatgtcgg acgtgggcac cgcgggtacc ccccttccgt cgccggaccc
     1741 gctcccgccg gtcacgtcac ggaccacgat ctcgtacggg atcagcacga tcgccgtggt
     1801 cccgccgtac ggcgacgggc gcagcgtgac ggtgacgccg tgccggtgcg cgaggcgtgc
     1861 caccacgaac atgccgagcc gcaggtcgtc ggcgagggcc accacgtcga actgcggtgc
     1921 caccgccagc tgttcgttga aggaggcgta gtcctcctcc gacatgccga gtccgcggtc
     1981 ctcgatctcg atcgccagac ccttggccac cagcgccgcc cgcacgccga ccgggttggg
     2041 ggcgggggag tacgcggtcg cgttgtcgat cagctcggcg agcaggtgga tcacgtccgc
     2101 caccgcgggc ggggcgaggc cgacctcctc gtcggcgtgc agctccacgc gctggtactc
     2161 ggcgacctcg ccgacggcgc tgcgcaggat gtcgaccagc gagacgggat cgcgccaggt
     2221 acgccggggc tgctcgccgc tgatgatgac gaggttctcc tcgtagcggc gcaactggct
     2281 cgctgtggag tccagttcgt acagcccctt gaggatctcg gggtcggtgt gctcgcgttc
     2341 cagcgcgtcc agcttgccga gctgcatgtt gacgaggttc tggctctgcc gggcgatgcc
     2401 caggatcacc ttctggaagc cgcgccgggt gtcggccagt tcgaccgcgg tgtgcacggc
     2461 ggtgcgctgg gccgtgttga acgcctgcgc gacctggccg agttcgtcgt gcccgtagtc
     2521 cagcggcggt gtcgccgact ccacgtcgac cttttcgccc cgctccagcc gggccaccac
     2581 gtcgggcagc cgctcctcgg ccaggccgag cgtggccagc cgcagcccgc gcaggcgccg
     2641 ggagagcgag cgggtgatgc gccaggagat gaagacgcag agcagcaggg ccaccaggcc
     2701 gcccgcgctg aggatgccgg ccttgatcag caggccgcgg gcctcaccgg cgctgcggtc
     2761 gaggagtccc tcggtctgct gccggatgag ctggccgtac tggacgcgga tcttctcgaa
     2821 ggcggtgacc cagcgctgcc gcgcgtcggg caggtcgatc cggttctccc cgcccgccgt
     2881 gcgggccgcg agcacctggt cctcgacgtc ctgcatcgac ttccactcgg cgctcgcgag
     2941 gatccgctcg gtctgcgtct tcgcactgcc gctcagggag ggcacgatct ggctctgcac
     3001 cagccaacgg cgggtgtgca ccagctgggt gaatcgcgtc cactgctcgt cgtccatccg
     3061 gtcggacggc caggccagcg tgagccgggc gtcctcctgg gaggccagct cggcggcctg
     3121 ctccagggag accagcgggc ccgcctgcga agtgaggtcg ccgtcgtcga cctgggagag
     3181 ctcctggaag gcgtggatct ggtcgtcgac gatcgaggtg aactggtcga gcgcctgctc
     3241 ggaggtgatg tcggtggggt tgtccacctg gctgcggtag tactcgaggc tggtcaccga
     3301 gccgagcacc gagtacagcc ggtccgagat acgggagggg gcgcggtcga tcgcgtcgga
     3361 ctggccgacc agctgcgcga ccgccgcgtc cgtcttctcg cgctgctcgt ccagtgccgt
     3421 ccggtcgccg tccggcgcgg ccagccacgc ggccgacagg ctgcgctcct gctgcagggc
     3481 cagggtggcc tcggtgccca tggcgccggt gtcgcggctc aactgcgtct gggcacgcag
     3541 ctgcagtccc tccgagaaca tctggatcgt cgtgacgctc cacatcccgg cgagggtgac
     3601 gcccggaacc agcgcgagga ggatcaggga gagacgtatg gagccgaggc ggcgccgggc
     3661 acccttcttc cgtgtcttcc gtgcaggcat tgtcgtccta ggcgatcagt gggtgggggc
     3721 ggatgtgcgc cggcgtcggc tgccgcgggg cccggtcacc gggtgcctcc cgcagcgtac
     3781 ttgccgacct cgtcggcgtt ctcgcgggtc acgaacgcgg gcccggtcag gaccggggcc
     3841 tcggtgccgc cgctgacgtt gccgttggtg cggtacagcc acagggcgtc caccgagagg
     3901 tagccctgga ggtacggctg ctggtcgacg gcgaactgga tgtccccgcg cttgatggcg
     3961 gcgatcaggt cctcgctgag gtcgaaggtg gccaccttcg ccttgctgcc cgcctcgtcg
     4021 accgagtcga ccgcggtcag ggcgaacgcc gcgccgttca tgaccacctc gtcgatgctg
     4081 ttgtcctgct tcagccgggc ggtgacggac gtgcggacgg cctccatgtc gctgccctcg
     4141 acgtagagca tctctgtctc gccctcgaag gtcttcttca cgccggcgca gcgtgcctcc
     4201 actgcgacgt tgccccgctc gtggatgacg cacagggcgt gcttggcctt gagggagttc
     4261 agcttgtcgc cgacggcgcg gccggcgacg ctctcgtcct ggccgaagta ggtcaacagg
     4321 ccggtcccac gccaggcgtc catgccggag ttgaggccga cgacggggat gccggcggcc
     4381 ttggcctcgg ccaccggtgc cttcatggcc tgcgttttgg ccagcgtcac ggcgatgccg
     4441 tcgaccttgt cgcggacggc gtcgcgcacc aggtcggcct ggtcggcggt gtcggcgtcg
     4501 cccgcgtagg tgaggtcgac gccgtccttc gcggccgccg cctccgcgcc cttgcggacc
     4561 cggtcccaga aggcgtcacc ctcgtcgccg tgggtgacca tgacgatcct catccggttg
     4621 gatccggacc cgcccgcggc gtctgccgcc gagccgtcct cgtccccgcc gaatacggag
     4681 cagcctgcgg ccagcagaca gacggccgcg gcgaaggccg cggcgcgcag aggtctgaag
     4741 gagtgggtgg acgggtgaga tgtactcatg ggggttgggg cacctcgctg tgcagccgag
     4801 caggaggaac gggacgagcg tcccggagcc gcgggtcagt gcgccaaccg ggtgaaactc
     4861 gcctggccgg agcaaaccgt gtgtgacggc tgggagtcaa gtgatcagcg acctggtgtg
     4921 agtcgtcggt gccgcatcgt gatgaacgcg gtcggcgaaa gcgggcggaa gcggaatccc
     4981 gggcggtatg cagccgcggg ggcgcacgtc cgccgtgctc ggcacccgac gtccggcacc
     5041 gggcgtccgg caccgggtat ccggaatcgg gtaccgggcg ggcggcggcg ggtattcgga
     5101 atcgggtgcc gggcgtccgg cgccgggtat tcggaatgcg gcagtgggcg ggcggcgccc
     5161 ggcgtccgcg ctccgggtgc gtgccggagc gcggatgccg ggcggtccgt gcgccgggtg
     5221 gtcaggcggt gccgcccgcg ccctgctcca ggggtggcgg ggccgtgcgt gcggcccgtg
     5281 ccgccttcct gcggcgtcgg cggtcgcggc gcgactcctg gtccggaagc cagccgaaga
     5341 ccaggcagct gccgacgcag ccgaggagca gcccgacgag gaagccgccc aggttggagg
     5401 tgatccaggt gcccagggag gccagcacgc cgatgaggga gtagaagagg cgctgggcgg
     5461 ggttcaccag cgccagcact ccgcacagca gcatcacgac cggcagcagg tacccggcga
     5521 cgccctgcat gccgacgtgg atcacgacct tgaaggacgc cttcatggtg aacaggacct
     5581 cggccccgcc cagggcgagc agcaggccgc cccagaacgg ccgtccggac cgccagtcgc
     5641 ggaacgcggc ccggaagccc ctgcgccggt cgccgggcat cagcagcccg acccgctgaa
     5701 gcgcagcttg aggccgggca gcttgaacac cgcggccgtg gtggcgtagt tggtctgacg
     5761 caggttcttg atgtgcacgg tgtcggcctg ctggctgaag acgccgatcg gtccgcgccc
     5821 cttcggtccc gccttgtcca gcgtgccggc gtcgttgccg atctcgatgt tgttgaagga
     5881 ggcgtcgccc gacaggaacg tcgagtcggt cgtcagattg ctcgcggaga cccgggtgct
     5941 cccgtcgccc gcggtgatga ggaggttggt gccgcccagg tcgacgctct ggcacagctt
     6001 ggtgagcttg gcgttctcga tcaccgaggt gacgaccagt acctggccgc cggtgtcgcc
     6061 ggcgttcgga ctgccctcgg ccatgttgtc gagtccgccg aactgggcga atccgttgcc
     6121 gtcgagttcc gtggcggtga cggtgaaggg catgccggag atggcgaact gcacgccgag
     6181 ggcgccctgg gcggtgagga ccgccagagt cgcggtgacg gcggcggcgg gcaccgcgag
     6241 gaccgcggcc cggcgcagcc tgacccggcc gggtctcgcg tgctcggagg tgttgccggc
     6301 ggacggggtg tcgtccgggg acggggccat gtctgctccc agaggcatag tgaacgcggt
     6361 tcgggcttca gcggcgcgtt gtcctggcgc ggacagcggc tggggcgcac gtctcccgtc
     6421 aactcccggc ggttgcaggg gcgttcacgt tacgcaccag tagccattcg ggaagttacc
     6481 ggtggttaca gtgcagggtc aagcaagttg tgagtaaaga gtgggggttg cgtgccgcct
     6541 gccgctttct ctgtgcggtg acctctgcgt tgcgcgagaa tgcgggcttc cttcgtccat
     6601 ctgcttgacg cagacacgac atcagcctta caactggctc tgtttcccgg atccgtggcg
     6661 ccggatccgt tcccgcggcg ctcgccgcat tcccggcccc gttctccacg ggggctccgc
     6721 cgcactcgcg ggtcagaccc gcgcccgccg gtgtcgcacc gtccgccggc ggctccgcgc
     6781 cgcgtgcacc accgttccca cgctccgagc ccggcaccgc accgcgcccg ccggaccgtc
     6841 acggcacccg tcacggacgc acggttcccg gaccccggca caccggcccg gccgggactc
     6901 cgcgcgccgg tccgactccg cttcaccgaa ccccacttca gagaagaggc agccgcatgc
     6961 gaacccgtac cctgctcacc ctcaccgccg ccgtcgccgc cctcgccctg ccggccgcgg
     7021 tccccgccgc ggccgccgcc gacaccccgg tcctcaccac cggcaccgcc ggcggcacac
     7081 ccgtcgcggt gggggacacc ctcaccgccc cgctggcgag cggcaccagt gccaccttcc
     7141 gctccagcgc gggcggcagc agcggcgtct cctgtacgtc ctcgcagttc accgtcaccg
     7201 tcaccgacaa ccccacggcc cccggcacgg ccaccgagtc gctcaccgcc cacaccttcg
     7261 acagcgccag ttgctccagc aacgtcaccg gcgtcctcgg tgtcaccggc atccaggtcg
     7321 ccaacctgcc ctacaccact accgtctcct ccgagggagc cgttgccgtc accccgccga
     7381 gtggttccac cgtccgcacc accgtgtccc tgcgcaccct gctcggcagc atcaactgcg
     7441 tctacgaggc cccgggcctg agcgggacgg cggccaacga cgacaactcg atcgccttcg
     7501 ccgaccagca cttcaccaag gtctccggct ccggactctg tttcgccgac ggctacttca
     7561 ccgccaccta cgcgcccgtg accgacggca gcgcgaccgt cttcgtcaac tgacggaaac
     7621 cgccccggca ccgtcccggc accgcgtcga aacccccggt ccgcccggcc cgccccgcaa
     7681 cgggcggacc gggccccggc acgtgcggac ggccggcaag ggtcctgatc tgacgggcag
     7741 ttagccggtg agttatcgtg tacagggggt gcagacaggc ggcacagcct gtgagttcca
     7801 gcccaggaga gatcagtcga tggcgaggca gctacgcgcc gagcagaccc gcgcgacgat
     7861 cgtcggcgcc gccgccgacc tgttcgaccg tcgcggctac gagtcgacca gcctgagcga
     7921 gatcgtcgcc cacgccggtg tcaccaaggg tgccctgtac ttccacttcg cggcgaagga
     7981 ggacctcgcc cacgccatca tggagatcca gtccacgacc tcgcgccgac tggcgacgga
     8041 gctggccgcc cggggctaca ccgcgctgga gtcgctgatg cggctcacct tcggcatggc
     8101 ccggctgtgc gaggagggtc cggtcctgcg cgccggactg cggctggccg ccgggggagt
     8161 gccggtacgg ccgccgctgc cgcacccctt caccgagtgg cgggagatcg ccacctcccg
     8221 gctgctggac gccgtccggc agtccgacgt gcacccggac atcgacgtgg cctccgtcgc
     8281 ccacaccctc gtctgctcca tcgtcggcac ccggctcgtg agcggcgccc tggaacctgc
     8341 cgggcggcag ccgcgccggc tggccgagat gtggcacatc ctgatccgcg gcatggtccc
     8401 ggtgacccgg cgcgcccgct acgtcaccct cgcggcccgc ctggaacgcg agacgcccac
     8461 ggcctgacgg agcccggggt cccgcgtgcc cggcgggtgc gcggccaggc cgccgtccgc
     8521 cgcgcgggag gcggctcccc cgacggcccg cgcggtacgg tgaggcgcat gcccgccacc
     8581 ccggccgagt ccgcccccgt catcctcggc gacgagccgg ggtccttccc gcacggcgtg
     8641 ctcgccgagc ggcaccccgc catcgtccgg caggtacgtg cggcgttccc ctacggcccc
     8701 gaagtgcggg acgccctcga cgcgctcctc gcgagctgcg ccgacggggt ggtcgaaccg
     8761 gtgcccgccg gagccgaccc caccggccgc gaccgggagc gctgggcggg ctggggcatg
     8821 gacgcctacg ccggccgctc ctggtacgac gtgccctggc tgtgggccga gagccacttc
     8881 taccgccggc tcctcgacgc cgtcgggtac ttcggccccg gcgtctggca aggcgtcgac
     8941 cccttccggc ccgccaagct cgccgaactc gacgccccgg agaccggcga ggaactcgcc
     9001 gccctcgaca cgctcgccga cctgcccgcc gaggagcgga tccgggccct gctgcacggc
     9061 tcgctctggg gaaaccgcgc ggacctcggc ttccgcctct ccgagggcgg caccggcacc
     9121 cgggaacagg tggacgccct ggtcgccgac gacagcgacg ccctgtggtc cctgctgccg
     9181 cccgccggga ccggccccac cggccccacc ggcgccgcgg gcgctgcgac acccgcccgc
     9241 cccaggaccc tgtgcctcgt cgccgacaac gccggccggg agctcgtccc cgacctgctc
     9301 ctcgtgtcgc acctgctcgc cgagggtcgc gtcgaccggg cggtgctgca cctcaagccg
     9361 tacccctact acgtctccga cgccacgccc gccgacctgc tcgacgcgct gcggcgcctc
     9421 gccgcggcgg gcggcacggc ggcggtgtac ggcgaacggc tgtggaacgc gctggccgac
     9481 ggccgcgtca ccgtccgcgc ccaccccttc tcctgcgcgc ccctgccgta cgcggagatg
     9541 cccgacgacc tgcgcgcgga gttcgccgcg gccaccgtca ccgtcctcaa gggagacctg
     9601 aactaccgcc gcctggtggg tgaccggtgg tggccgccga ccacgtcctt cgcggacgcc
     9661 accgggtact tccccggccc cgtcgccgca ctgcgcaccc tgaagtccga cgtggtcacc
     9721 ggcctgaccg ccgggaccga ggcggccctc gaagcgagcg gggagcggcg ctggcggacg
     9781 agcgggacgc acgcgctgat ccaggtgcgg cgctgagcgg gtccgggcgg tgtgccgggc
     9841 cggcaggagc gaggtgctga gccggccgcg cgagatgccg ggccggtgcg agcgaggtac
     9901 tgagcgcgga aagttcccgg attcggcgct tgttcacgcg atggtgtgat catgtgccgc
     9961 ccgggggatg tgcccgaagt gccctgggta gggcccggcc atgacgcaac agccgttcga
    10021 actcccgcac ttctacctgc cgcatcccgc gcgcctcaat ccccatctcg acgaggcccg
    10081 cgcccactcg acgacgtggg cccgcgagat gggcatgctg gagggatccg gggtctggga
    10141 gcagtccgac ctcgacgcgc acgactacgg actgctctgc gcctacaccc accccgactg
    10201 cgacggaccg gcgctctccc tgatcaccga ctggtacgtg tgggtcttct tcttcgacga
    10261 ccacttcctg gagaagtaca agcgcaccca ggaccgcctc ggcggcaagg cgcacctgga
    10321 ccggctgccc ctgttcatgc ccctggaccc caccgccggc atgcccgagc cggagaaccc
    10381 ggtcgaggcc ggcctcgccg acctctggac acggacggtg ccggccatgt cggccgactg
    10441 gcgccgccgc ttcgcggtcg ccaccgagca cctgctcaac gagtccctgt gggagctgtc
    10501 caacatcaac gaggggcgga tcgccaaccc cgtcgagtac atcgagatgc gccgcaaggt
    10561 cggcggcgcc ccctggtcgg cgggcctggt ggagtacgcg acggcggagg tgcccgccgc
    10621 cgtcgccggg acccggccgc tcagggtgct gatggagacc ttctccgacg ccgtccacct
    10681 gcgcaacgac ctcttctcct accagcggga ggtcgaggac gagggcgagc tgagcaacgg
    10741 cgtgctggtc ctggagacct tcttcgactg caccacccag gaggccgccg agctggtcaa
    10801 cgacgtcctc acctcccggc tgcaccagtt cgagcacacg gcgttcaccg aagtgcccgc
    10861 ggtggccctg gagaaggggc tggcgccgtc cggtgccgcc gccgtcgccg cctacacgaa
    10921 ggggctgcag gactggcagt ccggcgggca cgaatggcac ctgcgctcca gccggtacat
    10981 gaacaagggc gcgctgccca ccgccggctg gcaggccctg accggccccg gcacctcggc
    11041 cgcggacgtc ggcgcgctgc tcgccgccgc ggccgccgga cgcgcccgcc cctacgcctg
    11101 gacccccttc cagaaggtcg gaccgtccgt catcccggac atccgcatgc cgtacccgct
    11161 ggagctgagc cccgccctgg agggcgcccg gcgccatctg ttcgagtggt gcgcggagat
    11221 gggcatcctc agcgagggcg tctgggacga ggacaagctc gggagctgcg acctcccgct
    11281 gtgcgccgcc ggcctcgacc cggacgccac ccaggaccag ctcgacctcg cctccggctg
    11341 gctcgccttc gggacctacg gcgacgacta ctacccgctg gtctacggcc accgccgcga
    11401 cctggccgcg gcccgcctga ccaccgcccg gctgtcggcc tgtatgccgc tcgacggcga
    11461 accggtcccg ccgccggcca acgccatgga gcgctccctg atcgacctgt gggcgcgtac
    11521 gacggccggg atgacgcccg aggagcggga acccctgaag acggccgtcg acacgatgac
    11581 cgaggcctgg gtgtgggagc tggccaacca gatccagaac cgcgtccccg acccggtgga
    11641 ctacctggag atgcggcggg ccaccttcgg ctccgacctc accctgggcc tgtgccgcgc
    11701 cggccacggc ccctcggtgc cgcccgaggt ctaccgcagc ggccccgtcc gctccctgga
    11761 gaacgccgcg atcgactacg cctgcctgct caacgacgtc ttctcctacc agaaggagat
    11821 cgagtacgag ggcgagatcc acaacgcggt gttcgtcgtg cagaacttct tcggcgtcga
    11881 ctaccccgcc gccctccgcg tcgtgcagga cctgatgaac cagcgcatgc gccagttcga
    11941 gcacgtcgtc gcacacgaac tgcccgtcgt ctacgacgac ttccagctct ccgacgaggc
    12001 gcgggagatc atgcacggct acgtgaccga cctgcagaac tggatggcgg gcatcctcaa
    12061 ctggcaccgc aacgtgccgc gctacaaggc ggagtacctc gcggggcgca cccacggttt
    12121 cctcccggac cggatcccgg ccgtgcccgt ctccgcgtcc cggtcggtgc ccgtctccga
    12181 gtggggaagg agccccgtgc cgacgccctg accgacgttc agtctcactc tttcgtggct
    12241 cgtcacgcgc cggtgcgccg ggtagagcac ttcccggagg cgatccatgg aacagacagc
    12301 gttgcgtccc aagccgatgc ccggccggga accgggcacc ggcaccgaac ccgccgccgc
    12361 ccggcgtccg cggcccgggc gccggcgccg ccgggtcacc accgtgctgc tcggcgtgct
    12421 cgccgcgctc gtgctgctcc tcacgggcgt ggggctcggc acggtgggtg ccacggtggt
    12481 gggcatgagc agactcgccg agatgcagcg cgggccggcg gcgcaggaac cgggcgcggg
    12541 ggcctcgccg ggcacgcggg ccgccccggc gcacccgtcg gccgccccct cgccgtcccc
    12601 ggcgcgggcc ggggcgaccc tcggggtgga ggccgtggac gaccggaaac ccggggcccg
    12661 gatcgtgggc gtacacatgc ccggccccgg attcgcggcg gggctggtcc ggggcgacgt
    12721 actcctcacc ttcggtacga cccgcgtcga ctcggccgcc gacctcgccc acgcggtggc
    12781 ccgtgcccgc ccgggcaagg gggtcagaat caccgtgcgc cacgagagcg gcggctacca
    12841 gcagctcacc gccgtcccgg gcgtcgtcac gtgaccgcag gcgggcggct cgggaccggc
    12901 cggtgccgcc ccgaacgcgt gcggcacgcg tgcggcgcat accgggccgg gaccgaggtc
    12961 cgcgtcgcgg ccgggcgtcg cccgcgacgg gtgatccacg tcaattggct cgcgctgacc
    13021 ccgtgccggg ggcaggatgc tgctcgtagt gacttcgtcc ttcgcactcg ccccttcgcc
    13081 cagggaggcc cggatgaccg gcagccacgc cgccgcttcc ttcaccgccg acgactaccg
    13141 ggctcgcatg gaccgcgccg cgcgtgcggc cgccggcgcc gggctggccg gactcctggt
    13201 cgccccgggc ccggacctcg tgtggctcac cggctacacg ccgccggccg acaccgagcg
    13261 cctcaccctc ctcgtcctcg cccccgaccg cgaccccgtg ctcgtcgtcc cggcgctgga
    13321 ggcccccgac gcccggaacg ccaccggcgc gtccgcgctg accctgcacg actggaccga
    13381 cggcaaggac ccctacgcgg ccaccgccgc cctcctcggc gcgtccgggc gtttcggcat
    13441 cagcgacaac gcctgggcca tgcatctgct cgccctccag cggaccctgc ccggcacctc
    13501 ctacgcctcc ctcaccgagg cgctgcccat gctgcgcgcc gtgaaggacg cggccgagct
    13561 ggacctggtg gcggcggcgg gcgcggcggc ggacgaggcc ttcgaggaga tccgcgacgt
    13621 gcgcttcggc ggccgccgcg agtcggaggt cgccgccgac ctggccgggc tgctgcgccg
    13681 gttcgggcac tcccaggtcg atttcaccat cgtcgcctcg gggccgaacg gcgccaaccc
    13741 gcaccacgag gtgggcgacc gcgtcatcga ggacggcgac atggtcgtcc tcgacttcgg
    13801 cggcctgaag gacggctacg gctcggacac ctcccgcacc gtccacgtcg gcgaacccac
    13861 cgacgaggag cgccgggtgc acgacctggt gcgcgaggcg caggaggccg gcttccgcgc
    13921 ggtgcggccc ggcgccgcct gccaggacgt cgaccgggcc gcccgcgcgg tcatcgccgg
    13981 cgccggatac ggcgagtact tcatccaccg caccgggcac ggcatcggcg tcaccacgca
    14041 cgaaccgccc tacatgatcg agggcgagga gcagcccctc gtgcccggca tgtgcttctc
    14101 cgtcgagccc ggcgtctacc tgcccggccg gttcggggtg cgcatcgagg acatcgtcac
    14161 cgtcaccgag gacggcggcc ggcgcttcaa cggcacgacc cgggagctgg tcgtcgtgga
    14221 gtgaccggac gcggcgggac ccgggacgtc cggaagacgc ggcgcccccg gcggacgccg
    14281 cagacctggc agacccggca gacccggaag acggcggcgc gaccatgacc caggcaccga
    14341 cacccaccgc ggacaccgtc cgccgactgg tcggctccct gctcggcgga agcacggaac
    14401 ccgacgtccg gcccgtcgcc gcgggcgccg accccgccac ctggtgggtc ggcccccggc
    14461 acgtgctgcg gctggccccc gacggcgacg ccgccgtgcg ccagcgccgc gagctgcgcc
    14521 tgcgcgagct ggtccggccg cgcgtgccgg tcgcggtgcc gacgagcgtg gcgcacggcg
    14581 agtgggcgcc gggactgacc tacacgctgg acgccaggct gaccgggggc tcgggggagg
    14641 accacgacgt gtccgccctg ggcgaggcgg acctcgcggc gctgctgacc gggatgcgcg
    14701 aggtgccggg acggcaggcc gaggccctgg gcgtgccccg ggccgcccca cgctccctgg
    14761 agacactgcg ccggaccgcc gagcgggccg cccggcgcct ggccgaggcc gacgagttcg
    14821 acccggcccg gcccgagcgg ctgaccggcc aggcagcggc ccagctcggt gcccagcagg
    14881 gcacggcggt cctcgtccac cacgccctgg ccggcgagca cctcgtggtc ggcgccgacg
    14941 gccgggtgcg cggcgtcctc ggctggaccg acgcggtcct cggcgacccg gctgaggaca
    15001 tcgcggggct ggccctctgc gtcggcgcac ccgccgcggt ccgcgccgcc accctcgccg
    15061 gctacggcgc ccgcccctgc ctgcgcggcc tgtggctggc ccgctgcgac acggtcgtcc
    15121 agctcgccga cgcgctccac gggcggtccg gtccgccccc ggccgccctg ctcaggacgc
    15181 ggctgcggcg cgcctgggag ccgatcctgc tggaacgcgt gacggaacta cgcggagacg
    15241 acccggacga cgcgccctga agcccttcgg cccccagccc tcggcgtccc cgggcgccgc
    15301 gccgccgccg cgcccgtgcc gcccctcatt ccccctcgct cctgtccccc ccctgtcacc
    15361 ccctgtcact cctgcacgag taccacgctc gactcgcccg gcaggtggag gaggccgtcc
    15421 gggcccgggc ccgtcaccgg ttcccacgcg gccaggacgc gtgcggggcg gttgccgagg
    15481 gggatcgccg ccggtccggg gcccagattg acggccaccc ggatgtcgcc gcgccggaag
    15541 gccagccagc gggccgccgg gtcgtaggcc accctgctgt ccgcgaggtc ggggtcggtc
    15601 aggtccggct gcccggcgcg cagggcgatc agccgccggt accagtccag cacgcgcgcg
    15661 tgcggctcgc gtccgggctc ggaccagtcg aggcaggagc gctcgcgcgt cgccgggtcc
    15721 tgcgggtcgg gcacgtcctc ctcccgccag ccgtgcgcgg cgaactcgcg ccgcctgccg
    15781 tcgcgcacgg cccgcgccag ctccgggtcg gtgtggtcgg tgaagaactg ccacggcgta
    15841 ccggccgccc actcctcgcc catgaacagc atcggagtga agggcgccgt cagcgtcagg
    15901 gtggccgcgc aggccgccag gccgggggag acgagggcgg ccagccggtc gccctgggcg
    15961 cggttgccga tctggtcgtg ggtctggctg tagccggtca gccggtgcgc ggcggtgcgg
    16021 gcccggtcga gcgggcggcc gtggccgcgc ccacggaagc tggaccaggt gccgtcgtgg
    16081 aagtagccgc gggtcagcgt cttggcgagc gccgccagcg gatcgcgcgc gaagtcggcg
    16141 tagtagccct gcgactcgcc ggtcagcgcg gtgtgcaggg cgtggtggaa gtcgtcgttc
    16201 cactgcgcgt gcacgcccag accgccctcc gcgcgcggcg tgatgatccg cgggtcgttc
    16261 aggtcggact cggcgatcag gaacagcggg cggcccaggt cggccgcgag cgcgtccacc
    16321 gcggccgaca gctgctccag gaagtggcac gcgcgcgtgt ccaccagggc gtgcaccgcg
    16381 tccaggcgca gcccgtcgag ccggtagtcc cgcagccagg ccagcgcgct gcccaccagg
    16441 tacgcccgga cctcgtccga ccccggcgcg tccaggttga cggccacgcc ccagggcgtg
    16501 tggtgggtgt cggtgaagta ggggccgaag gccggcaggt agttgcccga ggggcccagg
    16561 tggttgtgga ccacgtccag gacgacgccc aggcccagtt cgtgggcccg gtccacgaac
    16621 cgcttcagtg cctcgggccc gccgtacggc tcgtgcaccg cccacagcga gacgccctcg
    16681 tatccccagc cgtgccggcc cgggaagggg cacagcggca tcaactgcac gtgggtgacg
    16741 cccagttcca ccagatggtc caggcgtgcg gcggcggcgt cgagcgttcc cgggggcgtg
    16801 aaggtgccca cgtgcagctc gtacaggacg ccgccgggca gtgggcgccc ggcccacggc
    16861 gtacgccacg ggtaccggtc gtggtcgacg accgcgctga gcccgtcggg accgtccggc
    16921 tgccggcgcg agcgcgggtc gggcagcacc ggcccgtcgt ccaccgcgaa gccgtaccgc
    16981 gagccgtccc gcgcctcgct ccggccgcac caccaccccg gccgctccgg atcctgctcc
    17041 agcgtgcgcg tgacgccgtc gcactccagc gtcacccggc cggcctgcgg tgcccacacc
    17101 tcgaactgca cggacggttc cccttcgtct gcccaccgtg acacagcccg tccatggtcc
    17161 tgcatcgggg gccggtccgc cggggaatgc cgccgcccgc cgcgggtgtc gtcggcgcac
    17221 cgcgcgcggc ggccgttctc gcgtcttctg gacacgtcgc cgcgactgac cgacaatcac
    17281 ctgcgtgacg tcgtccttcg agttcaacac gtaccccgcg cggttgtcgg acgcggagcg
    17341 cgacaaggcg ctcaaggtgc tgcgggacgg cgccgccatg ggacggctgt cccacgacac
    17401 cttcgtccgc aggatggagc tggcgctcac cgcccgccgc ccggaggagc tggcggtgct
    17461 caccgccgac ctgaacaccg agggacggct gtcgcggctg gtgttcggga ccgtcgaggc
    17521 ggtgtccggg ttcggcgccc ggctcgccac ggcctggcgg gccgagcggc tgcccaagct
    17581 gctgctgccc caccccggca ccggtcatcc gctgcgcata gggcgcgatc cggcgagcgg
    17641 gctgcggctg agccacgaga cggtctcccg ggtgcacgcg gaactcagcc gccagggcgg
    17701 catgtgggtg ctgcgcgacc tgggttcgac caacggaacc accgtcaacg gacggcgcgt
    17761 catcggtgcc gccgtggtcc gcgacggcga ccagatcggc ttcggacgga tggccttccg
    17821 cctcgcgggg gactgagacc gggccgccgc cgagcacacc cgtggccccg gcttcaccgg
    17881 gggtgatggg cccttgaccg gcgccatccc tttgcgtttc gcggtgttga cgtacccccc
    17941 aagtcgtgac tgactgtgcg tacaccgcgc acaccaggtg tatcgacggc ccgcatcgtg
    18001 gaggtgtgcc ctgccgcccc tcctgcgcta tccgaccgtg gacgagctgg gcgcccgggc
    18061 cgacgcactc gtcgcacgtc atccccggca cgcccggctg cgccgcgtcg gcacgtcccg
    18121 cgcgggcgcc ccgctgctgc tgctgtcggt cggccgcggc agccgccagg tcctcgtcgt
    18181 cgccggaccg cacgccaacg agcccgtggg cggcgccacc gccctgcggc tcgccgaacg
    18241 ggccgtcgcc gacctccgcc tgaccgaggg cgccgacgcc acctggaacc tgctgctgtg
    18301 cgtcgacccc gacggtctgc gtcgcaacga gggatggctg tccggcccgt acacgctcgg
    18361 ccgctacgcc cgcaacttct tccggcccgg cttcctggag cagcccgagt ggctgcccga
    18421 cggacccgac cgcgccgccc tgcccgagac ccgcaccctg ctcggactcc aggaggagct
    18481 gcgtccgttc ctccagtgct ccctgcacgg cgtcgacgtg ggcggcggct tcgtcgagct
    18541 gacccacgag ctgcccggca tcgccggccg cgtctcccac accgccgccc ggctcggcgt
    18601 accccgcgaa ctgggcgcct acgacaccct gtactggccc cagctcgggc ccgccgtcta
    18661 ccgcatcccg ccaccccgtc gcggcgactt caccgcggcc atcaccgagg ccgccgtcga
    18721 ctccacgtgg tgccacccgc agcgctacgg caccgtcacc gcggtcgtcg aggcgccgat
    18781 gtggggcgtg gcggccgtgg cggacgcctc gcccccctcc gaccgggacg cgatgctgcg
    18841 cttcgtgagc cacaccctgc ggcaggacgc ccggcggctg cagcgcctcc tcgcccggat
    18901 ccggccgcac ctcgccgccg tgcccggcgc cgcgcacctg ctcgccccgg tcgacgacta
    18961 cctgctcgtc tgccccggac tcgcggacac ctgggacccc gacaccgacg acgggtcggg
    19021 ccgcccgctg ccgccgatga gcaccgccca cctggtcgcg ctgcggctgg ccggacggcg
    19081 cctcgccctg cggaccgccg ggctgctcca ccagttggtc acccgcgcgg gggccgatcc
    19141 ggagggtgtc ctgccggaac tcgaccggct cgtcgacgag ggctgcgccg actacctgga
    19201 cggctgcggg gcccgctgga tacccgtcgc ccggcaggtg gagtaccaga cccgcgtcgt
    19261 cctggccgcc ttcgaactgg ccgggcggcg ccccgcggag gatccccgcc cggtcgaggc
    19321 gggccggggc ccgggagcag cggtgccgat gcaccgggag tgacctcccc gccgggacgg
    19381 cgtcattggt cccccacccg ctcgagaagc gccaccggcg tgtcggcgaa cagctcctcc
    19441 acgcgcgcgt gccccgtgaa ctcccgcccc ggtgccagcg tgtcggccca ccgtcccggc
    19501 ggcagcggca gcgtcgtccc gcgccagccg ccctcctggg ccagccgcag cgacagccgg
    19561 gtcacggccg tcaccacgtc accggagcgg gcgaacgcca cgcagtgctc cgccgcgggc
    19621 ccctcggcgc gcacgggttc gtacgtcgcc gcgccgccga aggccccggg ccgccgcgcc
    19681 cgcagcgcga gcgccgcacg ggtcaccacc gtcttgcccg cgccacccgt gctgcccgcg
    19741 ccacccgcgc cacccgtgct gcccgcgcca cccgcgccac ccgtgctgcc cgcgccaccc
    19801 gcgccgcccg cgccactcgc gccgcccgcg ccgcccgcgc cgcccgcgcc actcgcgcca
    19861 ctcgcgccgc ccgcgccgcc cgcgccgccc gcgccactcg cgccgcccgc gccgctcgcg
    19921 ccgcccgcgc gctccccgct ctccccgtcg ctcccggttg ccgggtgggc cgtcgggaag
    19981 tcgaccggtc gccggttgtc cgggtccacc agggccaggt actcgtgctc ggtgccctgg
    20041 tagaggtccg gcacgcccgg catcgtcaga tggaccaggg cggtgccgag gacgttggcg
    20101 cgcacgtgcg gttccacggc cttgcgcagc tcggccaccc gctcgcccgg cgccccgcac
    20161 ggccccgccg ccacgaacgc ctccaccgcc tcctcgtacg acgccacccg ctccgtccag
    20221 ccggtgtgca ggcccgcctc gcgcacgtgc ttgagcagcg cgtcccggac ccgcccgccg
    20281 tccgccgggc ccagcccgaa caccgtctgc caggccgccc acgcgagctg ggggtccggc
    20341 gccccctcac ccgcgcgggc gacctccgtc aggacgtccg cccaccgcgc gggacactcg
    20401 gtcagcaccg cgagggccgc gcgcacgtcg gcgctgcgct tggtgtcgtg ggtcgacacc
    20461 accgtgcccg tcgcgggcca gtcgcgctgc acgcgcgcgc agtaggcgtg gaagacctcc
    20521 ggatcgaggg ccggcccccc cgggttcccg cccacctccg tcgccgacag cagcggcacg
    20581 tagcggtaga aggccgtgtc ctcgacggac ttggcccgca gcgcggaggc ggtctgcgcg
    20641 aaccgggccc ggaactcctc gtggtcgggt ccgtccccgt accgccccag gaccaggtcc
    20701 cgtacgacgt ccaccgcgcc ggcctcctcg ggcaccgtga acgcgagccg cgcctcggcc
    20761 gccgcctccc ccgtgacgac ctccccggcg tcggccgccg tgtacggccg gtacacctcc
    20821 agccgcacca gcagttcccg caacgccgtg cccagcgccc acggcgcccg gtcgcgcggc
    20881 gcgggctgcg gcgaggcggc gcacaggcgg tgggccagcc gggtcaggcg gtccagctcg
    20941 gtggccagct cgtgcgtcag cacccggtac gccgcccgcc gcaccgtcgc cgcccagtcg
    21001 ccgccccggt ccggctgcgg ggcggcgaag gcccggtacc gtccgaggag ttccccgtac
    21061 cccgccgggt cggtgaagag cccgtcgacg tggcgcaggg cgtcgtagcc ggtcgtcccg
    21121 gcgacgggcc aggcggctgg gagccgctcc ccgtccgcga ggatcttctc gaccaccgtc
    21181 caccgcccgc cggtcgcctc gtgcagccgc gccaggtagg cgcccgggtc ggcgagcccg
    21241 tcggggtggt cgacgcgcag cccgtcgacg acgccctcgc gcagcagccg cagcaccgtg
    21301 gcgtgggtgg cctcgaacac ctccgggtcc tccacccgca ggccgatcag ctccgagatg
    21361 ctgaagaacc gccggtagtt cagctcggtg cgggccagcc gccaccacac ggggcggtac
    21421 cactgcgcgt ccaggagctg cggcagcggc aggtccgcgg tgccgtcccg cagcgggaac
    21481 gcgtgctcgt ggtagcgcag tacgccgccg tcggcccgga ggtcgtccag cacctcgccg
    21541 accggggccc cgagcaccgg cagcagcacc tgaccgccgc ccgcccgcca gtcgatgtcg
    21601 aaccaccgcg cgtacggcga ctcggggccc tcgcgcagca cctcccacag ggcgcggttg
    21661 tggcgcggcg acatcgccat gtggttgggc acgatgtcca ccaccaggcc gagaccgtgc
    21721 tcccgcgcgg tgcgcgccag cgcgcgcagc ccctcctcgc cgcccagctc cgcgcgcacg
    21781 cgcgcgtggt cgacgacgtc gtagccgtgc cgcgagcccg ggaccgcctc caggacgggg
    21841 gacaggtgca ggtgcgacac gccgagcgag gccaggtacg gcacggccgc cgccgcggcc
    21901 tcgaagcgga agtcgggctg cagttgcagc cggtaggtgg ccgacgggac gggggaggcg
    21961 gccggggacg gcaccgggcc gggtcgctca ggtgtcatgg agacctacgt acccgccccg
    22021 ccgcctttcg tgtcaccggc cccctgcacg ggtgaaggaa gcgcgccccg ggccggccct
    22081 tcacaccggc cgctgcagca ccgtcagact ccggtccacc agggtcagcc ggtccccggc
    22141 ctgcaccttg gggcccgtct gcgaggggac cggatccggg cgggaggtgt ccacgacgac
    22201 ctcccactgc c
//
