LOCUS       NZ_CP036534            28188 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. VN1 chromosome, complete genome.
ACCESSION   NZ_CP036534
VERSION     NZ_CP036534.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. VN1
  ORGANISM  Streptomyces sp. VN1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8341703)
  AUTHORS   Nguyen,H.T., Pokhrel,A.R., Nguyen,C.T., Pham,V.T.T., Dhakal,D.,
            Lim,H.N., Jung,H.J., Kim,T.S., Yamaguchi,T. and Sohng,J.K.
  TITLE     Streptomyces sp. VN1, a producer of diverse metabolites including
            non-natural furan-type anticancer compound
  JOURNAL   Sci Rep 10 (1), 1756 (2020)
   PUBMED   32019976
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8341703)
  AUTHORS   Pokhrel,A.R., Nguyen,H.T., Dhakal,D., Nguyen,C.T., Pham,V.T.T. and
            Sohng,J.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2019) Department of BT-Convergent Pharmaceutical
            Engineering, Institute of Biomolecule Reconstruction, Sunmoon-Ro221,
            Asan, Chungnam 333-708, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: HGAP3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011650445.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 03:53:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,284
            CDSs (total)                      :: 7,197
            Genes (coding)                    :: 7,083
            CDSs (with protein)               :: 7,083
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 44 of 114
            Pseudo Genes (incomplete)         :: 82 of 114
            Pseudo Genes (internal stop)      :: 3 of 114
            Pseudo Genes (multiple problems)  :: 15 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:32:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4243451
            Orig. end                         :: 4271639
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036534.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jae Kyung Sohng.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28188
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="15"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..28188
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28188
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18188](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18188)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    36..50
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     gene            233..892
                     /locus_tag="EZV63_RS18895"
                     /old_locus_tag="EZV63_19150"
     CDS             233..892
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959866.1"
                     /locus_tag="EZV63_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19150"
                     /product="hypothetical protein"
                     /protein_id="WP_166624548.1"
                     /transl_table=11
                     /translation="MTPVLLPLGALLAASVLAAPMAGAAPQADRPASAPSGWEKVDGAE
                     LAEITKDSDATKQAPLAEGKASARAAEPDVWAFASRYNGRFVATEKSYAAPNTGVLRAR
                     SAEFSGSWEEYELEWDDATETYALKSHANDRYVTVEQNYTGNTQNVLRARSTSVGGWER
                     FVFWYNETEERWALQSASNGLFVTMENNTTGKLQYVLRARSASVGGWESFDLYSVI"
     gene            complement(973..3543)
                     /locus_tag="EZV63_RS18900"
                     /old_locus_tag="EZV63_19155"
     CDS             complement(973..3543)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014717.4"
                     /locus_tag="EZV63_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19155"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_166624549.1"
                     /transl_table=11
                     /translation="MFDIAWSTIKNRKGGFVAAFIAVICGSAVITACGVLFVSGLLSGV
                     APERYAGATVMVGGRQTKDVKENFDPYYAERVTVPASVAEQISRVDGVEKVVRDHSVEM
                     TLQKDDGSARGEPMPLEHPLYGHGWSSAALGPFELAEGSEPGGVGETVLDSGLARAAGV
                     KVGDTVRLSVGTTPQDYKVAGLVDAPGGGLDRQSAAFFTDARAAGLSQRPDRLTAIGVL
                     GEDGTDAGELAGRIEAAVTGTDVVAYTGDAIGDLEFLDVGQSRGFLVMLSASFGGTALG
                     VVVFVVSSTLGLAIHQRRRELAMLRAVAATPRQVHKLIGSEVLLVAATGAVLGAAPGFL
                     VAGLLRDAFADVGVLPADFELSFNPLPAVAAVLLSVLGALLAGFIAARRIARIKPVEAL
                     SESQVEKGELGRTRKAVALALLGLGLVTSIVLPLLIPGQLAIAGAGGSLLLLMVGSALI
                     SPVLVQTTTRLLTPLLMRSKVSGYLAAANSTTNARRLSSAVVPLALGTAMALMQLSMLN
                     TVEVTAKEQAATGVVSDYVVTSGTTGLSTDLAQKVRAVDGVGTVTPVARSQVLITYVEI
                     DKPVSNPFSAQGLEPRDLDRTLDLDVREGSLDELRGDTVALSRIAADTARLDVGDTADV
                     DLGDGTHKELKVVALYGKGLGFGDVTLPHGMLTGHTANQQDTALLVTGEDGGGGAGGKV
                     ESGLADLADGTPGLVVQSPEEFGAVEQGEFTQQSSTSLIANALLILYVLIAVVNTLVMA
                     TTGRSREFGMLRLIGTSKQQTRRMMFLESWVVILTAVVVGIAIAIPPAVGAALGTTGQP
                     IPYVEPLAWGGIVVFVALLGWLSISLPTRSALRGRPIDAVYATE"
     gene            complement(3554..4297)
                     /locus_tag="EZV63_RS18905"
                     /old_locus_tag="EZV63_19160"
     CDS             complement(3554..4297)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007827456.1"
                     /locus_tag="EZV63_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19160"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_211269688.1"
                     /transl_table=11
                     /translation="MTVGTQTAAMRLDSVTKTYGEGDNAVTALRGISLEVPRGTFTAVM
                     GPSGSGKSTFLHCIAGLDQPTTGRVFLGDTELSGLKEAQLTAVRRERIGYVFQAYNLMS
                     ALTVRQNITLVARLADMAVDEAWLRELLTRVGMSEYVDRRPGQLSGGQQQRVAIARALA
                     TRPDALLADEPTGALDTRTSQEVLKLFRQVVDEIGQTVLMVTHDPVAASYADTVLFLAD
                     GQLAGRLYKPSPAEVAEHMTHLGDW"
     misc_feature    4395..4410
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     gene            complement(4432..4629)
                     /locus_tag="EZV63_RS18910"
                     /old_locus_tag="EZV63_19165"
     CDS             complement(4432..4629)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EZV63_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EZV63_19165"
                     /product="hypothetical protein"
                     /protein_id="WP_166624550.1"
                     /transl_table=11
                     /translation="MDLRRAGGTPAAREDPAGTECGEPLRAERGVLVLRTGTGEARVPL
                     ADATALLPVDTCPGAGSRNG"
     gene            complement(4620..5609)
                     /locus_tag="EZV63_RS18915"
                     /old_locus_tag="EZV63_19170"
     CDS             complement(4620..5609)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310749.1"
                     /locus_tag="EZV63_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19170"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_227730235.1"
                     /transl_table=11
                     /translation="MYRAFLFQDEDAHRPAQLADSADDCVKAAVARLIDLSLLTPSRES
                     PGGLRAVDPSRGMRVLLQQEQHELARREHRIKHNTTMLDLLASEYAAVRRQAHSDGVER
                     LYGADHISTRLEALAESCRHESLAFYLEPPAHPAHPADPGDRPADEPGQAAVPPRLYEQ
                     ALARGARLRSIYLDGIVRDDATRSHALWTVEHRGEVRTAPSLPMGLLIVDTTAAVVGGL
                     PGEDPESVLLFSGKPVVLAVRALFEAYWDHSDRFPCDDFGDAQADEVTPQERKLLELLA
                     EGLTDGAVARALGISVRTERRKVAELMDRLGVSSRFAAGVQATRRRWI"
     misc_feature    complement(5671..5686)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     CDS             5769..5969
                     /gene="allorf_4249220_4249420"
                     /locus_tag="allorf_4249220_4249420"
                     /protein_id="allorf_4249220_4249420"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRTGRGGTRGRRLPCAPPRPRHVAATCLAGSCQIMVQTGALHDDF
                     LSLPVDADGRGGATAEGVVEK"
     CDS_motif       5769..5858
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRTGRGGTRGRRLPCAPPRPRHVAATCLAG"
                     /locus_tag="allorf_4249220_4249420_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5859..5969
                     /prepeptide="core"
                     /locus_tag="allorf_4249220_4249420_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="3650.0"
                     /monoisotopic_mass="3647.8"
                     /core_sequence="SCQIMVQTGALHDDFLSLPVDADGRGGATAEGVVEK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRTGRGGTRGRRLPCAPPRPRHVAATCLAG"
                     /leader_location="[5768:5858](+)"
                     /alternative_weights="3668.0"
                     /alternative_weights="3686.0"
                     /alternative_weights="3704.0"
     CDS             5966..6121
                     /gene="allorf_4249417_4249572"
                     /locus_tag="allorf_4249417_4249572"
                     /protein_id="allorf_4249417_4249572"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSAPRPRRRSACAARRSGRVPEDGDADISRQAGTCRRAGKVRTAH
                     RRRKTP"
     CDS_motif       5966..6007
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSAPRPRRRSACAA"
                     /locus_tag="allorf_4249417_4249572_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6008..6121
                     /prepeptide="core"
                     /locus_tag="allorf_4249417_4249572_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="4118.5"
                     /monoisotopic_mass="4116.2"
                     /core_sequence="RRSGRVPEDGDADISRQAGTCRRAGKVRTAHRRRKTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSAPRPRRRSACAA"
                     /leader_location="[5965:6007](+)"
                     /alternative_weights="4136.6"
                     /alternative_weights="4154.6"
                     /alternative_weights="4172.6"
                     /alternative_weights="4190.6"
     misc_feature    complement(6433..6446)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            6487..7278
                     /locus_tag="EZV63_RS18920"
                     /old_locus_tag="EZV63_19175"
     CDS             6487..7278
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991789.1"
                     /locus_tag="EZV63_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19175"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_031040638.1"
                     /transl_table=11
                     /translation="MLFRILGHLRIREELELRSPLRRAILTALLLRPGRPVGMTELAEL
                     LWDDPPSSALANLRSHFTGLRRDLDRAQPGLSRRITTCRGSQSGYRIEAGPNEIDLPTF
                     VDASRQGRNLLARGELDGAIAMLEGALTLWRGPFGQDLPVTRWFDAHATGLRNGRLDTY
                     EDLFTALLMARRTEMLSYRIETVVAEAPYRQRLWELLAAVYCVQGDAVSALGVLNRCRA
                     VLVEDLGLDVPPSVEAMRGAALTWDSEEALRLITRAPLARS"
     gene            complement(7345..8700)
                     /locus_tag="EZV63_RS18925"
                     /old_locus_tag="EZV63_19180"
     CDS             complement(7345..8700)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     conventional flavin-dependent halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016693.4"
                     /locus_tag="EZV63_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19180"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_166624552.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.2e-25,
                     bitscore: 89.0, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTENVDVVVVGGGPAGSTAAGLLAKAGHEVLVLERETFPRYHI
                     GESMVSGMAPLMEELGLVAELDARFQHKSGITLRWGKDPEPWRSDFSAAFSSTGSHFTH
                     AWHVTRSEFDELLLDNARSLGAKVHEAAQVTEVLKDESGRTTGVVYTQGGETHRATARF
                     VVDASGQGRLLTRRLTQTSWQEDLRNVAVWSYFDSYTPLDHKDDILVEAIEGGGWVWGI
                     PLSDTRLSMGYVLPVDKLTEEARAGRTQRDVFLDCLRRSNLAKTMVDVEALGELSTTRD
                     WSHVCDTFHGPGWVAVGDSAAFIDPLFSSGVWLGTSGAWLAARALDAALRDEDREEASL
                     QHFDAVYRQLFQDILAYVRFFMDPTRLREEYEERAREIGNMVTQSSRVGFISMISGVSA
                     VADVVDFDPMNVEEVEDLMQEWDEQASGSREADGAGRGPGVATVPQGTPATP"
     gene            complement(8789..9775)
                     /locus_tag="EZV63_RS18930"
                     /old_locus_tag="EZV63_19185"
     CDS             complement(8789..9775)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991781.1"
                     /locus_tag="EZV63_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19185"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_037766227.1"
                     /transl_table=11
                     /translation="MKYSILLPVTPARPEQAVLFANLVQWTAAERLWQGQSLVLDSHHL
                     ATWLAGIGVRVPMGFGVSLMPLRSPYQAAFEARSVALATGHPVVAGFGPGPVSFQQAVL
                     GRPYARPLQASREYATVVRRLVSGADAAVEGQYFSVAARLLKRPAPPVEVGLGVLRPKM
                     AALAGEVADRAITWLLPAAHLAGTVIPAVRGADRTLGTPARTTAIVPVAVARAGRDATA
                     LAEATCGNHLKAAHYQDALRKAGIPVSERGDAQDAALVVDAGAFLYGTEDQIHERLAEF
                     AAAGVDEVVLNTTGVAQLHGPKAAAQDLLQLLGGVRGGSAAEAGPVL"
     gene            complement(9786..9974)
                     /locus_tag="EZV63_RS18935"
                     /old_locus_tag="EZV63_19190"
     CDS             complement(9786..9974)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EZV63_RS18935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EZV63_19190"
                     /product="hypothetical protein"
                     /protein_id="WP_166624553.1"
                     /transl_table=11
                     /translation="MSREENTMSENKRAGMAASFPLFVGAVVAAAAAAQENWGGAALGL
                     VAGVVISLILVARRRKR"
     gene            complement(10001..12922)
                     /gene="lanM"
                     /locus_tag="EZV63_RS18940"
                     /old_locus_tag="EZV63_19195"
     CDS             complement(10001..12922)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="EZV63_RS18940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19195"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_166624554.1"
                     /sec_met_domain="DUF4135 (E-value: 6.5e-59, bitscore:
                     198.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.6e-20, bitscore:
                     70.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVQVATDARPATGPTAAADAHVVTEPQVAVEDFLPFYRNRIPR
                     QVVVDRLRGPLSQAAAPEHAGTLVDQVWEDLVTAVEGHSLRVLIGEFHEFRQSRGLPAT
                     AGSDEAISRFRRHIEDPDNCRELLGRYDVLRRRLTVVLDRFLDAYDDLFTAFRDDRPRL
                     VERGLLTDGGDTLASLITTGGDPHNDNRRVVGVRLAGGGRLVFKPRTLAADDFVRDLYA
                     VVDPYLAHSLGGCVPESLSVGDHGWQSFVTPRAMTGPDQPARYFYRFGALCALFGAIGA
                     SDLHDENLLAAGEHPCVIDTEMMLRPGSGTGDGSLEQRLNNHVEASVASTMLVPNVRPE
                     SPIDVIMAGVGVSGEQVSGKMKKSALQDGGTDALRLRWEPIVYQHKENVPRLGDEKLAS
                     VRFYRDIVAGYTDALGAVRERRAIEEVIGRYAELPVRCLIRSTMVYGRFLDAATQPRYL
                     RDAGESERFLGLLKQFPRQLAPEARAFAGEAERVAMDTGNVPYFTGRAGTTELATHTDR
                     LPGAHPSSPADAARAGLALHAAQSDRYHRFVLEECFGELAEAAPDVMSAQSVFAPVLDT
                     PAGEPWWPHIARILQDIQVTYSDADGVQCGWVGGVGPDRGVPTLLPGNYLSFHDNGGIV
                     TFLQDAAEHDPRFAELYRRADRGLSALLQVYDEAQLRAPESVFTGAASMMLTRPRRQDR
                     AWTARLLERVPERIEAGTLEKDLANGPAGLLMAVLARLEAGQDRLMDEEQLGRLCDLVL
                     GQAATPLDRAWYDVAHGDVGMWWAVSRIGRYLGDAALSGEAADRLTERLSAGELPPVPG
                     WCNGSAGVLLVSAEILTSAGRPEVLTGGRLAELLDGATSSRGDRPVDLSVCHGSSGVVQ
                     SLIATSRLLEDRSLLGRAAEYREQTARAAGARGFHTGCPGRTSLLGYMFGWSGIGHTDL
                     MLDEALDGRAPAFVPVALTAAGAPEEPAPPRRPGANVRASAAR"
     gene            complement(12919..15147)
                     /locus_tag="EZV63_RS18945"
                     /old_locus_tag="EZV63_19200"
     CDS             complement(12919..15147)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991785.1"
                     /locus_tag="EZV63_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19200"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_224219933.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.2e-28, bitscore:
                     95.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTATQKTDTQKKDTRGKVRTARRVPTVTQVTQTECGLCSSIA
                     LLRYYGRAEEIVSARSVMEAGRDGLSASQLAQFLESRGMRVKPYRVRNVAALANFTSPV
                     ILYWENYHFVVLESFDGRTAVVMDPAVGRRRISRAELEKSFTEIVLSAEPGDTFERKRA
                     TPFAEWRKFLVITAETKKRIALVALLSLSGYGTVLGIPVLTRWAVDRYAQWQGFGDAAV
                     VLAAVLAAAVCYLALHLTRVVLLSSLIAVLGKDLMSQTFTRLLNLPFKFFTTRPPGELM
                     YRLNSVTAVRDLVSSRTAQGVLDVGTLLCVTVYLLVTEWRLGSVAVGIFLLNALYLMKT
                     RYRVTEAVDSEIAYLAKSQGTQLDAIVSIPAIKMGGYAEEFLRGWNETYGNSLDAMRTR
                     MRLQQGRIAGLSTTTQMFGPLILLLLSLYMVSHGSISLGAAVSVQAISATYFSLANSVF
                     QTYTSFNEVSRYVARLSEISDEEPEAAGGDRTELVAPSVTLKNVDFRFTLHSELVVRNV
                     SMTIGAGERVALVGPSGSGKSTLGRIICGLYEATGGTIEYGGHDLGEYDRSALRRTIGY
                     IPQEVHMHNRTILENLTLGKDLSEEYVREFCGRLGILDFVEELPMGYQTLVSDMGANFS
                     GGQRQRIAIARALLGDPKILVMDEATAALDNINERRVLRAISEIGATQIVIAHRLATVK
                     SADRIYVFDNGTITEAGTHESLLGDGDLYADLYGEDDLERTLVAGERA"
     gene            complement(15150..18188)
                     /locus_tag="EZV63_RS18950"
                     /old_locus_tag="EZV63_19205"
     CDS             complement(15150..18188)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179558.1"
                     /locus_tag="EZV63_RS18950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19205"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_166624555.1"
                     /sec_met_domain="DUF4135 (E-value: 6.3e-70, bitscore:
                     235.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.5e-43, bitscore:
                     147.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSAINYYPEFDDTEIEETITPLAAFDDEVRAVVSREPQQPAVLP
                     SRPGVVKDWTARAEEYPFQQVVRDIAAGAADGDPLAAFPGLFADRDDALTELLDRAEAR
                     IRELYTRPLVAAVNHAREQGSLLGETPRERYRYFVDEAVRGSVASAGGLDFPVLRNLTP
                     VVLAGTVDSVVELCSRLVADRAAIRDTFGIAVEDRLVSFGRPQGDTHHHGRAVCILAFE
                     SGTRLVYKPRDVSCEAGFAVLADEFNAAFGTRLHAVTALARDGYGYVEYVETEDVSAIS
                     ERFLYESGELAAVLYLLNARDMHFENIVPTRRGPVPVDLETVLHPERIHVGPVPEADGN
                     AYGTIGRSVYGVGILPLVMAGRRGDQGGHVDLGFLGGPGRGASPFKQMSFDEPYTDRIR
                     LSLKAQEVSARRTVVGERTEEEILRLGRSMADGFTRTYRAVLAAPGTWTALLRKAADGL
                     RIRYVHNPTALYSQTLRMVTGPSALDDTDTYLALLKRIAIASKTSDRTLIASELRQLAE
                     RDVPYFTVSATGTRVCDGDGREVGAAFGSSPLDLALDKAAGLGETDLGEQLRLIRSAFT
                     AQFPDNHLTPARPTEAPSGGGADSGERAALTSLARELTDGLVATSLPDRFAHLPRTWIG
                     PLASAEADRPWPPGVLGYDLYTGRTGIALTLAAAGRVLDDERCLAVARQIFSTTGEILA
                     SHRYETRSLQQAGYAGYTGMSGILFCLSAAGRLIGEEAWVSAAQGAVPLVLEQIRAVPV
                     DELPLDVISGLAGVLNCFAAVADPTGSGVAAPEGREAVTEVALLLTRALGRDGALARSV
                     LDQSGFAHGISGVVHALGRAHPLLPAEHRAPVGTALTDLVRRLDTFYDPAERNWSSQLS
                     RQGSFATGWCHGATSVALALSGAAGVLGHETVAARRDQAVENTLRLGFGRNLTWCHGDL
                     GNHGALRFIAGPDGSPLHDEVRQKERQWLRPEVMRRKLADPDSRYAHTNSLMVGSAGLA
                     LHLLNRIDPGLRLCPLTLTVEGR"
     misc_feature    complement(18280..18294)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(18302..18315)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.76"
                     /tool="antismash"
     gene            complement(18358..18522)
                     /locus_tag="EZV63_RS18955"
     CDS             complement(18358..18522)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237615.1"
                     /locus_tag="EZV63_RS18955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_164711404.1"
                     /transl_table=11
                     /translation="MRENQKDFLGAYDEAELIELSEADVTGGTTPVSVAVSVAASVAFC
                     PTTKCTKEC"
     CDS_motif       complement(18490..18522)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRENQKDFLGA"
                     /locus_tag="EZV63_RS18955_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18358..18489)
                     /prepeptide="core"
                     /locus_tag="EZV63_RS18955_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.70"
                     /molecular_weight="4247.7"
                     /monoisotopic_mass="4245.1"
                     /core_sequence="YDEAELIELSEADVTGGTTPVSVAVSVAASVAFCPTTKCTKEC
                     "
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRENQKDFLGA"
                     /leader_location="[18489:18522](-)"
                     /alternative_weights="4265.7"
                     /alternative_weights="4283.7"
                     /alternative_weights="4301.7"
                     /alternative_weights="4319.8"
                     /alternative_weights="4337.8"
                     /alternative_weights="4355.8"
                     /alternative_weights="4373.8"
     misc_feature    complement(18525..18540)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.84"
                     /tool="antismash"
     gene            complement(18557..18721)
                     /locus_tag="EZV63_RS18960"
                     /old_locus_tag="EZV63_19210"
     CDS             complement(18557..18721)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237622.1"
                     /locus_tag="EZV63_RS18960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19210"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_037766215.1"
                     /sec_met_domain="mature_ha (E-value: 1.4e-10, bitscore:
                     39.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQGDLSLIEEIEEQDFDGVAYGACTTNTFSLSDALGNHGGWCTL
                     TKECQPNCS"
     CDS_motif       complement(18650..18721)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MYQGDLSLIEEIEEQDFDGVAYGA"
                     /locus_tag="EZV63_RS18960_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18557..18649)
                     /prepeptide="core"
                     /locus_tag="EZV63_RS18960_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="3079.3"
                     /monoisotopic_mass="3077.3"
                     /core_sequence="CTTNTFSLSDALGNHGGWCTLTKECQPNCS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MYQGDLSLIEEIEEQDFDGVAYGA"
                     /leader_location="[18649:18721](-)"
                     /alternative_weights="3097.4"
                     /alternative_weights="3115.4"
                     /alternative_weights="3133.4"
                     /alternative_weights="3151.4"
     gene            complement(18963..19724)
                     /locus_tag="EZV63_RS18965"
                     /old_locus_tag="EZV63_19215"
     CDS             complement(18963..19724)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="EZV63_RS18965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19215"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_031040619.1"
                     /transl_table=11
                     /translation="MSSLNAAVDFEWSKVRTVRSMVWSLVLCVALSLALAVVTGAVVRR
                     QYADEPAPSSFDPVSAGFSGLRLGMIGLVVFGVLAVTSEYSTGTIRSSLAAVPRRGVFY
                     AAKMLTGGLAAGAVSCVAVLTSFFLAQATMGEESVSLTDDGVPAALVGAVLFTTLLCLF
                     SMGVAALLRSSVLTMGILMPLFFTVSTILTNVPGVGRAAQFLPDQAGGLALYRHAPDGY
                     VLNAWSGLAVLAAWTAAALGAGYLALRRRDA"
     gene            complement(19724..20641)
                     /locus_tag="EZV63_RS18970"
                     /old_locus_tag="EZV63_19220"
     CDS             complement(19724..20641)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173620.1"
                     /locus_tag="EZV63_RS18970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19220"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_037766208.1"
                     /transl_table=11
                     /translation="MIEVRELTKRYGKVRAVDGLSFRVEPGRVTGFLGPNGAGKSTAIR
                     AMVGLDRPTSGEVLVDGKRYEDLPRPLTTVGALLDARAVHGGRSVRGHLAGLARSNRLP
                     ARRVDELLETVGLASVADKRAKGLSLGMSQRLGIAAALLGDPQTLLLDEPVNGLDPEGV
                     KWVRDLVKRVAGEGRAVLISSHLMSEMALTADHLIVIGRGRLLADTPAHDFITGNSRSY
                     VLIRTPEPERMRDLLAARGVQVDHGPDGSLEAVGTDQKTVGTLAAESRIALYEVTTTTA
                     SLEDAFMQFTADSVEYRAEQGAAR"
     misc_feature    20608..20623
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            complement(20943..21251)
                     /locus_tag="EZV63_RS18975"
                     /old_locus_tag="EZV63_19225"
     CDS             complement(20943..21251)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018106117.1"
                     /locus_tag="EZV63_RS18975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19225"
                     /product="transcriptional regulator"
                     /protein_id="WP_031040612.1"
                     /transl_table=11
                     /translation="MDADFDAFLHPAPRLTIVALLAPADWTEFGFIRDTIGTSDSALSK
                     QLSALAAEEYIEVRKQPASAGRRKLARLTPKGREAFARHAAALERIAVTARTARPAD"
     gene            complement(21251..21757)
                     /locus_tag="EZV63_RS18980"
                     /old_locus_tag="EZV63_19230"
     CDS             complement(21251..21757)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571767.1"
                     /locus_tag="EZV63_RS18980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19230"
                     /product="hypothetical protein"
                     /protein_id="WP_051159658.1"
                     /transl_table=11
                     /translation="MPTDDQHDGSAVDQHALTPADARAALDDIRTRREQSGAAELRFAL
                     SRPSLLTAALLLFVSFASFDLPNPWGGAVLLPGLLLVALLVLRHTYGAPVRNRPGTRGV
                     LLGVVGGLAGYAVFRGLAAALSAGGVPTPHLLSAAVVVGGCLLAAPRVREVADARLRGR
                     ADRRR"
     misc_feature    21804..21822
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.97"
                     /tool="antismash"
     misc_feature    complement(21821..21837)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.17"
                     /tool="antismash"
     gene            21881..22864
                     /locus_tag="EZV63_RS18985"
                     /old_locus_tag="EZV63_19235"
     CDS             21881..22864
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547826.1"
                     /locus_tag="EZV63_RS18985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19235"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_063741515.1"
                     /transl_table=11
                     /translation="MKPLMLEGLSKRFGSQQALEKLTLAVRPGEITGFVGGNGAGKTTA
                     MRIGVGVLEPDEGRVLWGDAPVTRAETERFGYMPEERGLYPKMTVARQLTYLGELHGLS
                     RAEARDAMVRWTERLRITQHRDKRVATLSLGNQQRVQLAAALVHDPDVLLLDEPFSGLD
                     PLAVDDMSEVLRTKAEQGVPVLFSSHQLDLVEQLCDRVAIVRAGRLAACGTHQELRPAD
                     SRGQVYVEIDGAGGDWPADCAAAAAHRAHEQGVLVDLAAGRTENDLLAQAARHGTIRQM
                     RRHEPSLAELFRDLVEPADDPPTDRGEPDAPASDPARTSDLDKVSA"
     gene            22861..24036
                     /locus_tag="EZV63_RS18990"
                     /old_locus_tag="EZV63_19240"
     CDS             22861..24036
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024110.4"
                     /locus_tag="EZV63_RS18990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19240"
                     /product="ABC transporter permease"
                     /protein_id="WP_052410823.1"
                     /transl_table=11
                     /translation="MKRPGSRQHTLRPTRVRLVYTRELRARMCTRGYVVGLALLSLVTF
                     GLVMGFSMLGGTGDSTVAVCGAPAESTGTAPPGIRVTSCDGMTDGRKLVENKDADAAVV
                     VTGNRATLLSRADTGDQAKAGAEALATSWAGHQALLRQDVDLQRLERDTAAAELTTVTV
                     GKSVGTLQLGAAATLIIVLFTQIVNQGSVIAQGVVEEKSTRVVEVLLATLTPLELLMGK
                     VAGIITAGMVQVATMLGAVVCGQALVSDTSTELPGAQALVVTVLWFLLTFALFASLYAA
                     AGSLVSRPEDLQGVLTPVMLLALAPVGTATAAATDLSASWISVVQYIPPFSGLLMPLKA
                     SVGTANLPEQLIAAALLLAATVCCITLAARIYSNSVLRVGAPVRWRQALAA"
     gene            complement(24251..24955)
                     /locus_tag="EZV63_RS18995"
                     /old_locus_tag="EZV63_19245"
     CDS             complement(24251..24955)
                     /EC_number="2.7.7.-"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007492065.1"
                     /locus_tag="EZV63_RS18995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19245"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_166624556.1"
                     /transl_table=11
                     /translation="MDGIDAARAVVEKQHPEARTAFLGGSVATGRGTATSDLDIVVLLH
                     GAPAPYRESLQYAGWPVEMFVHTEATWHAYIDRELPTRRSPLLWMCAAGLVLFDTDGLG
                     ARLAAHARKLTDAGPPPVPAEEIDDHRYAITDLLDDLAGSTDRSERLFIAGELVRRTGE
                     LALAIAGSWGGGGKWLARRLETAVPGLGARLHHGLQEVLSGRVEPLVAVVDEVLGQVGG
                     RLWVGYKRAGTP"
     CDS             complement(25080..25289)
                     /gene="allorf_4268531_4268740"
                     /locus_tag="allorf_4268531_4268740"
                     /protein_id="allorf_4268531_4268740"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIRHGARPPHTRPTEAAHLQRFDQEKDQTTWTQPLPNLIRDDEVV
                     GSNPATPTDETPGQGPDPQCGSGP"
     CDS_motif       complement(25149..25289)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MIRHGARPPHTRPTEAAHLQRFDQEKDQTTWTQPLPNLIRDDEVVGS"
                     /locus_tag="allorf_4268531_4268740_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(25080..25148)
                     /prepeptide="core"
                     /locus_tag="allorf_4268531_4268740_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.20"
                     /molecular_weight="2085.1"
                     /monoisotopic_mass="2083.9"
                     /core_sequence="NPATPTDETPGQGPDPQCGSGP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIRHGARPPHTRPTEAAHLQRFDQEKDQTTWTQPLPNLIRD
                     DEVVGS"
                     /leader_location="[25148:25289](-)"
                     /alternative_weights="2103.1"
                     /alternative_weights="2121.1"
                     /alternative_weights="2139.2"
     gene            complement(25305..26132)
                     /locus_tag="EZV63_RS19000"
                     /old_locus_tag="EZV63_19250"
     CDS             complement(25305..26132)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024487.4"
                     /locus_tag="EZV63_RS19000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19250"
                     /product="C-terminal helicase domain-containing protein"
                     /protein_id="WP_227730240.1"
                     /transl_table=11
                     /translation="MTGGLTVLTDTRGRPALANRSAVIWTDVTGRAARPPFGGSWVNED
                     EIRKVQDSVRYLLEQLPLEATVGVVTPFTAQAETLRKRLRPYDEERLRIGTVHTFQGGE
                     RDVMVFSLVAGEGMHPGAVEWIGGQLNLWNVAITRARGHLIVVGDKELWRNRGGVGTAL
                     LEAADRNGVPLGGGDDDVLLKRLYRILSLAEGATVTLGETVHGHPVDALVGGTSTTTMR
                     AVLLDRGVEESSDAARHLRLMLHRRNLLSSEDGKVEAIRWPAWRLYETGERRE"
     gene            complement(26129..26482)
                     /locus_tag="EZV63_RS19005"
                     /old_locus_tag="EZV63_19255"
     CDS             complement(26129..26482)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EZV63_RS19005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EZV63_19255"
                     /product="hypothetical protein"
                     /protein_id="WP_037766200.1"
                     /transl_table=11
                     /translation="MTSTNPAGPDPAARPKRRTFSPEYKLRIVAEYDAALKNEKGAVLR
                     RERLYHSHVKEWRAARDAGALEKLVDQRTGPARPKKSAAEAENEKLRRQVERLEKELAR
                     NQAALIVLGRLLL"
     gene            complement(26511..27128)
                     /locus_tag="EZV63_RS19010"
                     /old_locus_tag="EZV63_19260"
     CDS             complement(26511..27128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354767.1"
                     /locus_tag="EZV63_RS19010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_19260"
                     /product="hypothetical protein"
                     /protein_id="WP_051159656.1"
                     /transl_table=11
                     /translation="MAIARRSGDELIHANGRTVGKLADFWSWACSDLTSNTVRGVLAEY
                     LVATALGAATGTRTEWDAVDIRTPQNWRIEVKSTAYLQSWAQSQTSKVSFGIAPASGWD
                     ARTDITPADALRSADVYVFCLLHHREKQTLDPLDLGQWTFYVLPTHVLDERCRLQKTIT
                     LASLESLKPLKTGFVGLPEAVSACAGPSLPASGETSRFVGSA"
     CDS             complement(27182..27301)
                     /gene="allorf_4270633_4270752"
                     /locus_tag="allorf_4270633_4270752"
                     /protein_id="allorf_4270633_4270752"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRPGFGSQLGVIFGIRLPVTPQGAAFCLFSARAYASRPG"
     CDS_motif       complement(27257..27301)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRPGFGSQLGVIFGI"
                     /locus_tag="allorf_4270633_4270752_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(27182..27256)
                     /prepeptide="core"
                     /locus_tag="allorf_4270633_4270752_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="2516.8"
                     /monoisotopic_mass="2515.3"
                     /core_sequence="RLPVTPQGAAFCLFSARAYASRPG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRPGFGSQLGVIFGI"
                     /leader_location="[27256:27301](-)"
                     /alternative_weights="2534.9"
                     /alternative_weights="2552.9"
     tRNA            complement(27360..27433)
                     /anticodon=(pos:complement(4270848..4270850),aa:Pro,
                     seq:cgg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EZV63_RS19015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EZV63_19265"
                     /product="tRNA-Pro"
     gene            complement(27360..27433)
                     /locus_tag="EZV63_RS19015"
                     /old_locus_tag="EZV63_19265"
ORIGIN
        1 ggagttgtgg ggttgcctgc aagaggaggg gaaagaagtt tcgattaatt cactgtcttc
       61 acgcgtcctc caccgtttac gctgtggcgg ttgcgtcacc aggcgcgacc gctgccgaag
      121 tgcccgggga ggggcaccga ccgcagtcgc aggggggcga gagctacggg aaccaccgtc
      181 tcgccgtgcc cggacccgtt ccacgaatgg tgaggaattg actgtgagac gtatgacccc
      241 cgtccttctg cccctcggcg ccctgctggc cgcctccgtc ctggccgcgc cgatggccgg
      301 agccgctccg caggccgacc ggccggcgtc cgcccccagc ggctgggaga aggtcgacgg
      361 cgccgaactg gccgagatca ccaaggactc ggacgccacc aagcaggcac cgctcgccga
      421 gggcaaggcc tccgcgcggg cggcggagcc cgacgtgtgg gccttcgcgt cgcgctacaa
      481 cggccggttc gtcgccacgg agaagtcgta cgccgccccc aacaccggcg ttctgcgcgc
      541 ccgttccgcc gagttcagcg gctcctggga ggagtacgag ctggagtggg acgacgccac
      601 cgagacctac gcgctgaagt cccacgccaa cgaccgctac gtgacggtcg agcagaacta
      661 caccggcaac acccagaacg tgctgcgcgc ccgctccacg agcgtcggcg gctgggagcg
      721 gttcgtcttc tggtacaacg agaccgagga gcggtgggcg ctccagtccg cgtcgaacgg
      781 tctcttcgtc accatggaga acaacaccac cggcaagctt cagtacgtgc tgcgcgcccg
      841 ctccgcgtcg gtcggcggct gggagtcgtt cgacctctac tcggtcatct gacccgagca
      901 ggcgccccgc acacggcggt gaccgcccgc gagctgctcc agccgcgggc ggtcaccgcc
      961 gtacgcgcgt cctcactccg tcgcgtacac cgcgtcgatc gggcggccgc gcagggccga
     1021 gcgggtcggc aggctgatcg acagccaccc cagcagggcg acgaagacca cgatgccgcc
     1081 ccaggccagc ggctcgacgt acgggatcgg ctggcccgtc gtgcccaggg cggcgcccac
     1141 ggccggcggg atcgcgatgg cgatgccgac gaccacggcg gtgaggatca ccacccagga
     1201 ctccaggaac atcatccgcc gcgtctgctg cttgctggtg ccgatcagcc gcagcatgcc
     1261 gaactcgcgg ctgcgacccg tcgtcgccat gaccagcgtg ttcaccacgg cgatgagtac
     1321 gtacaggatc agcagcgcgt tcgcgatcag gcttgtcgag gactgctggg tgaactcgcc
     1381 ctgctcgacg gcgccgaact cctcgggact ctgtacgacg agaccggggg tgccgtcggc
     1441 caggtcggcc agcccggact ccaccttccc cccggcaccg cccccgccgt cctcgccggt
     1501 gaccagcagg gccgtgtcct gctggttggc ggtgtgcccg gtcagcatcc cgtgcgggag
     1561 ggtgacgtcg ccgaagccga ggcccttgcc gtagagggcg acgaccttca gctccttgtg
     1621 cgtgccgtcg ccgaggtcca cgtcggcggt gtcaccgacg tccagccggg cggtgtcggc
     1681 ggcgatccgg ctgagcgcca ccgtgtcgcc gcgcagctcg tccaggctgc cctcgcgcac
     1741 gtccaggtcg agggtgcggt ccaggtcgcg cggctccagg ccttgggcgc tgaaggggtt
     1801 cgagaccggc ttgtcgatct cgacgtaggt gatcagcacc tgcgagcggg ccaccggcgt
     1861 gacggtgccg acaccgtcga cggcgcggac cttctgcgcc aggtcggtgg agaggcccgt
     1921 ggtgccgctg gtgaccacgt agtcggagac gacaccggtc gccgcctgct ccttcgcggt
     1981 cacctcgacc gtgttcagca ttgacagctg catcagcgcc atcgcggtgc ccagcgccag
     2041 cggcaccacc gcgctgctga gcctgcgggc gttggtggtg ctgttggccg ccgccaggta
     2101 gccgctcacc ttcgaccgca tgagcagcgg cgtcagcagg cgggtcgtcg tctgcaccag
     2161 gacggggctg atcagcgcgc tgcccaccat gagcagcagc agcgaaccgc cggcccccgc
     2221 gatcgccagc tggccgggga tcagcagcgg cagcacgatc gacgtcacca ggccgagtcc
     2281 cagcagtgcg agggcgacgg ccttgcgggt ccggcccagc tcgcccttct ccacctgcga
     2341 ctcgctcagc gcctccaccg gcttgatcct cgcgatccgg cgagccgcga tgaacccggc
     2401 cagcagcgcg cccagtacgg acagcagcac ggcggcgacg gccggcagcg ggttgaacga
     2461 cagctcgaag tcggccggca gcacccccac gtccgcgaag gcgtcccgca gcagtccggc
     2521 caccaggaag ccgggcgccg cgcccagcac cgcaccggtg gccgccacca gcagcacctc
     2581 gctgccgatc agcttgtgca cctggcgcgg tgtcgccgcg acggcgcgca gcatggccag
     2641 ttcgcgacgg cgctggtgga tggcgagacc gagggtcgag gagacgacga agacgacgac
     2701 gccgagcgcc gtgccgccga acgaggcgga cagcatgacg aggaagccgc gggactggcc
     2761 gacgtccagg aactccaggt cgccgatcgc gtcaccggtg taggcgacga cgtcggtccc
     2821 ggtgacggcg gcctcgatcc gcccggcgag ttcgcccgcg tcggtcccgt cctcgcccag
     2881 gacgccgatc gccgtcagcc ggtcgggacg ctgggagagg ccggcggccc gcgcgtcggt
     2941 gaagaacgcg gccgactgcc ggtccaggcc gcctccgggc gcgtcgacca gcccggcgac
     3001 cttgtagtcc tgcggcgtcg tcccgaccga gagccgtacg gtgtccccga ccttcacccc
     3061 ggccgcgcgg gcgagaccgg agtccagcac cgtctcccca acgccgcccg gttcggagcc
     3121 ctcggccagc tcgaaggggc ccagcgcggc cgacgaccag ccgtggccgt acagcgggtg
     3181 ctccagcggc atcggctcgc cgcgtgcgct gccgtcgtcc ttctgcagcg tcatctcgac
     3241 ggagtggtcc cgtacgacct tctcgacgcc gtcgacgcgg gagatctgct cggccaccga
     3301 cgccggcacg gtgacgcgct cggcgtagta cgggtcgaag ttctccttga cgtccttggt
     3361 ctgccggccg ccgaccatga cggtcgcgcc ggcgtaccgc tcgggtgcga cgcccgagag
     3421 cagcccggac acgaacagca cgccgcaggc ggtgatgacg gccgagccgc agatcacggc
     3481 gatgaaggcc gcgacgaacc cgcccttgcg gttcttgatg gtgctccatg cgatgtcgaa
     3541 cacgacggcc gcctcaccag tcgccgaggt gcgtcatgtg ctcggcgacc tcggccggtg
     3601 acggcttgta cagccggccc gccagctgcc cgtcggcgag gaagagcacc gtgtcggcgt
     3661 aggacgcggc gaccgggtcg tgggtcacca tcagcacggt ctggcctatc tcgtccacga
     3721 cctgccggaa cagcttgagg acctcctggc tcgtgcgggt gtccagcgcg ccggtcggct
     3781 cgtcggccag cagcgcgtcc ggccgggtcg ccagggcgcg ggcgatcgcg acgcgctgct
     3841 gctggccgcc ggagagctgg cccgggcggc ggtcgacgta ctcgctcatc ccgacccggg
     3901 tcagcagctc gcgcagccac gcctcgtcca cggccatgtc cgcgaggcgc gcgacgaggg
     3961 tgatgttctg ccgcaccgtc agcgccgaca tgaggttgta ggcctggaag acgtagccga
     4021 tccgctcccg tcgtacggcc gtcagctggg cctccttcag gccggacagc tccgtgtcgc
     4081 ccaggaagac gcggccggtg gtcggctggt cgagcccggc gatgcagtgc aggaaggtgc
     4141 tcttgccgga accggagggc cccatgacag cggtgaaggt gccgcgcggg acctccaagg
     4201 agatgccccg cagggcggtg accgcgttgt ccccttcgcc atacgttttc gtgacggagt
     4261 ccagcctcat ggccgccgtc tgcgtaccca ctgtcatgtg cgcgtgccct tccggttgtt
     4321 ggcagcttca ccgtaggggg acgccggacg gggcaacgag ccacctgggg cccgtatcgg
     4381 gggtggggcc aggtacaccc ctggggcgtg ggaggcgagt ggtgcgcggg atcagccgtt
     4441 gcgtgacccg gcgccggggc aggtgtccac cggcagcagc gccgtcgcgt cggcgagggg
     4501 caccctggcc tcccccgttc cagtcctcag caccagcaca ccgcgctcgg cgcgcagggg
     4561 ctctccgcac tccgtgcccg ccgggtcctc acgagcagcc ggggttcctc ctgcgcgcct
     4621 cagatccacc gccgacgggt cgcctgcacc ccggccgcga accggctgga gacgccgagc
     4681 cggtccatga gctcggccac tttccggcgc tccgtgcgca cgctgatccc gagcgcccgt
     4741 gccacggcgc cgtcggtcag gccctcggcg agcagttcga gcagcttgcg ctcctgaggg
     4801 gtgacctcgt cggcctgcgc gtcgccgaag tcgtcgcagg ggaaccggtc ggagtggtcc
     4861 cagtacgcct cgaacagcgc ccgcacggcc aggacgaccg gcttgccgct gaagagcagc
     4921 accgactccg ggtcctctcc gggcagtccg ccgaccacgg cggccgtcgt gtccacgatc
     4981 agcagcccca tcgggaggga gggggcggtc cgcacctcgc ccctgtgctc caccgtccac
     5041 agggcgtggg aacgcgtcgc gtcgtcacgc acgatgccgt cgaggtagat cgaccggagg
     5101 cgggcccccc gggcaagggc ctgctcgtag agtctcggtg gcaccgccgc ctgaccgggc
     5161 tcgtcggccg gcctgtcccc ggggtcggcg ggatgggcgg gatgggccgg gggttcgagg
     5221 tagaaggcca ggctttcgtg ccggcaggac tccgcgagcg cctcaagacg cgtactgatg
     5281 tggtccgcgc cgtacaaccg ctccacaccg tcgctgtggg cctgtctcct gacggccgcg
     5341 tattcgctgg cgaggaggtc gagcatggtc gtgttgtgct tgatgcggtg ttcccggcgg
     5401 gcgagttcgt gctgttcctg ctggagcagc acacgcattc cgcgcgacgg atcgacagcc
     5461 ctcaggcctc ccggggactc cctggaaggg gtgagcagcg acaagtcgat gagccgcgcg
     5521 acggcagcct tgacgcagtc gtcggcgctg tcggcgagtt gtgccggccg gtgggcgtcc
     5581 tcgtcctgaa acaggaaagc gcggtacact tcaagcgtat tctggtcaag tggtgccact
     5641 tctttcattt cgtcccccgt tgcgtcgcgc tggaatatgc atccgagggc cgcacttcgc
     5701 aactcactga tgcgaaccgt cacggccgcc gcgatgctcc gccaccagtt tgcacggtcg
     5761 tcgcaagagt gcggacggga cgtggtggga cccgcggtcg acgactcccg tgtgccccgc
     5821 cgcgcccgcg tcacgtggca gctacctgct tggcaggtag ctgccagatc atggtgcaga
     5881 caggcgcact tcatgatgat ttcctctcct tgcccgttga tgcagatggg agaggtgggg
     5941 cgaccgctga aggtgtggtc gagaagtgag cgcaccgcga ccccgccgac ggagcgcgtg
     6001 tgcggcccgg cgaagcggcc gcgtccccga ggacggtgac gcggacatct cgcgccaggc
     6061 ggggacctgc cgccgggccg gcaaggtgcg gacggcgcat cgccgccgga aaacgccata
     6121 gaggaacaga ggctggaaag ccggcacaaa cagacagaaa cagactcggg ggagtggttc
     6181 ggatgttcag tcgtgccgca cggcccgtcg ggttcggaac attaccgagc cggcggcgtg
     6241 acgcccttcg ggggccatcg cggaccgcgt gcggtgatcg cggcagagac cacggcgaat
     6301 gaccaacacc cgagttccgg gcgcgccgtt cacttttgcc cggaaagtac gttagatcta
     6361 cacatcgagg aattgtgggg gacaattatg acctcgggca tgcgaaattc gacttctgcg
     6421 agaccctttt ccgcaacggt ggtgccgttc accgtcgcgt gtccccctct tcgctgaggg
     6481 ggcgcgatgc tgttcagaat tctcggacat ctccggatac gggaagagct tgaacttcgc
     6541 tccccactgc ggcgggcgat tctcacggcc cttctcctga gacccggtcg gcccgtcggg
     6601 atgacggaac tggccgaact cctgtgggac gacccgcctt cgtccgccct ggccaacctc
     6661 cgcagccact tcaccggtct gcggcgcgac ctcgaccgtg cccaaccggg gctgagccgg
     6721 aggatcacga cctgccgcgg ctcccagagc ggctaccgga tcgaagccgg accgaacgag
     6781 atcgacctgc ccacgttcgt cgacgcctcc cggcagggcc gcaacctgct ggcacggggc
     6841 gaactcgacg gcgccatcgc catgctggag ggcgcactga ccctgtggcg cggtccgttc
     6901 gggcaggacc tgccggtgac gcgctggttc gacgcacacg cgacgggact gcgcaacgga
     6961 cgcctcgaca cctacgagga cctcttcacc gccctgctca tggcgcggcg gaccgagatg
     7021 ctctcctacc gcatcgagac ggtcgtggcg gaggcgccct accggcagcg cctgtgggag
     7081 ctcctggccg ccgtgtactg cgtccagggt gacgcggtga gcgccctggg cgtgctcaac
     7141 cgctgccgcg cggtcctcgt cgaggacctc ggtctcgacg tgcctccgag cgtcgaggcg
     7201 atgcggggcg cggcgctcac ctgggacagc gaggaggcgc tccggctgat cacgcgggcc
     7261 cccctggccc ggtcgtaggc tcccggcatc accgcgccgg ccggcgtccg cacggacgcc
     7321 ggccggcgcg gtgatgccag gacttcaggg cgtcgcgggc gtcccctggg gcacggtcgc
     7381 gacgccgggc ccgcggcccg ctccgtcggc ctcccggctc ccggacgcct gctcgtccca
     7441 ctcctgcatg aggtcctcga cctcctcgac gttcatcggg tcgaagtcca cgacgtccgc
     7501 gacggcgctc acacccgaga tcatcgagat gaagccgacc cgtgaactct gcgtcaccat
     7561 gttcccgatc tcccgcgccc gctcctcgta ctcctcgcgc agccgggtcg ggtccatgaa
     7621 gaagcggacg taggccagga tgtcctggaa caactggcgg tagacggcgt cgaagtgctg
     7681 cagcgacgcc tcctcccggt cctcgtcccg cagcgcggcg tcgagcgccc gggccgcgag
     7741 ccacgccccg gacgtgccca gccacacgcc ggacgagaac agcgggtcga tgaacgcggc
     7801 ggagtccccc accgccaccc agcccgggcc gtggaacgtg tcgcacacgt gggaccagtc
     7861 gcgtgtcgtg ctcagttcgc cgagcgcctc cacgtcgacc atcgtcttcg cgagattgct
     7921 cctgcgcagg cagtccagga agacgtcgcg ctgggtacgg cccgcccggg cctcctcggt
     7981 gagcttgtcg acgggaagga cgtaccccat gctcagcctg gtgtccgaga gcgggatgcc
     8041 ccacacccag ccgccgccct cgatggcctc gacgaggatg tcgtccttgt ggtcgagggg
     8101 ggtgtaggag tcgaagtagc tccagaccgc gacgttgcgc agatcctcct gccagctggt
     8161 ctgcgtcagc cggcgggtca gcaggcggcc ctgaccggag gcgtcgacca cgaaccgcgc
     8221 ggtggcccgg tgggtctcgc cgccctgcgt gtagaccacc ccggtcgtcc tgcctgactc
     8281 gtccttgagg acctcggtga cctgggcggc ctcgtggacc ttcgcgccga ggctgcgggc
     8341 gttgtcgagc agcaactcgt cgaactcgct gcgcgtgacg tgccaggcgt gcgtgaagtg
     8401 gctgcccgtc gaggagaacg ccgcggagaa gtcgctgcgc cacggttcgg ggtccttgcc
     8461 ccaccgcagg gtgatcccgc tcttgtgctg gaagcgggcg tccagctccg ccacgagccc
     8521 cagctcctcc atgagcggtg ccatgccgga caccatggac tcgccgatgt ggtagcgggg
     8581 gaaggtctcc cgctccagga cgagtacctc gtggccggcc ttggcgagca ggccggcggc
     8641 cgtggagccg gccgggccgc cgcccacgac gacgacgtcg acgttctcgg tgcgcgacat
     8701 ggggtcctgt tctctctact aggaggtctc tactgggaag tggtgcgtgt ctcgggtcgt
     8761 gtacggaggg gagcaagagg gcgcgcggtc agagcaccgg gccggcctcg gccgccgaac
     8821 cgccgcggac tccgccgagg agctgcagaa ggtcctgggc ggccgctttg gggccgtgca
     8881 gctgcgcgac accggtcgtg ttgaggacga cctcgtccac gccggcggcg gcgaactcgg
     8941 ccagccgctc atggatctgg tcctcggtgc cgtacaggaa ggcgcccgcg tccacgacca
     9001 gcgccgcgtc ctgcgcgtca ccccgctcgg acaccgggat cccggccttg cgcagcgcgt
     9061 cctggtagtg ggccgccttc agatggttgc cgcaggtcgc ctcggccagt gcggtggcgt
     9121 cccggcccgc acgggcgacc gcgaccggca cgatggccgt cgtgcgcgcc ggtgtcccga
     9181 gcgtacggtc ggcaccgcgc accgccggga tcaccgtccc ggcgaggtgg gcggcgggca
     9241 gcagccaggt gatggcccgg tcggccacct cgcccgcgag ggccgccatc ttcgggcgca
     9301 gcacgccgag acccacctcg accggcggcg ccggacgctt cagcagccgg gccgccacgg
     9361 agaagtactg gccctccacc gcggcgtccg cacccgacac cagccggcgc acgacggtgg
     9421 cgtactcccg ggatgcctgc agcggtctgg catacggccg tccgagcacg gcctgctgga
     9481 aggagaccgg tcccggaccg aacccggcca ccacggggtg cccggtcgcg agcgccaccg
     9541 agcgcgcctc gaaggccgcc tggtacggcg accgcagcgg catcagggag acgccgaacc
     9601 ccatcgggac gcgcaccccg atcccggcca gccaggtggc caggtgatgg gagtcgagga
     9661 ccagcgactg cccctgccac agccgctcgg ccgccgtcca ctgcacgagg ttcgcgaaca
     9721 gcaccgcctg ttcggggcgg gccggcgtca ccggcagcag aatcgagtac ttcatcgcgt
     9781 gccgcctacc gcttgcgccg gcgcgccacg aggatcagcg agatgacgac gccggccacc
     9841 aggcccagcg cggcgccgcc ccagttctcc tgggccgccg ccgctgccgc cacgacggcc
     9901 ccgacgaaca gcggaaacga agccgccata ccggcccgct tgttctcact catggtgttc
     9961 tcttccctac tcatggtgtg cttttccttg ccttgggccg tcaacgcgcc gcgctcgccc
    10021 ggacgttcgc tccgggccgg cgcggcggtg ccggctcctc cggcgctccg gcggcggtca
    10081 gcgcgaccgg tacgaaggcc ggcgcccggc cgtccagcgc ctcgtccagc atgaggtcgg
    10141 tgtggccgat gccggaccag ccgaacatgt agccgagcag cgaggtcctc cccggacagc
    10201 cggtgtggaa acccctggcc ccggccgccc gcgccgtctg ctcgcggtac tccgccgccc
    10261 gcccgagcag cgaccggtcc tccagcagcc ggctcgtggc gatcagcgac tggacgacac
    10321 cgctggagcc gtggcacacc gacaggtcca ccggccggtc tccgcgcgac gacgtcgccc
    10381 cgtccagcag ttccgcgagg cgtccgccgg tcagcacctc cggacggccg gccgacgtga
    10441 ggatctccgc cgagaccagc agcacgcccg cgctgccgtt gcaccagccc ggcaccggcg
    10501 gcagctcccc ggcggacagc cgttccgtca gccggtccgc ggcctcgccc gacagggccg
    10561 cgtcgcccag gtaccggccg atgcgggaga cggcccacca catgccgacg tccccgtgcg
    10621 ccacgtcgta ccaggcgcgg tccagcggtg tcgcggcctg gccgagcacc aggtcgcaca
    10681 gtcggccgag ctgctcctcg tccatcagcc ggtcctggcc ggcctcgaga cgcgccagga
    10741 cggccatgag gaggccggcg gggccgttgg ccaggtcctt ctccagcgtg ccggcctcga
    10801 tccgctccgg cacgcgctcc agcagccgcg ccgtccacgc gcggtcctgc cggcggggcc
    10861 gcgtcagcat catcgaggcg gccccggtga acacgctctc cggagccctc aactgggcct
    10921 cgtcgtacac ctggagcagc gcgctcagtc cgcggtcggc acgccggtac agctccgcga
    10981 aacggggatc gtgttccgcg gcgtcctgca ggaaggtgac gatccctccg ttgtcgtgga
    11041 acgacaggta gttgcccggg agcagggtgg ggaccccgcg gtcgggtccc accccgccga
    11101 cccagccgca ctgcacgccg tccgcgtccg agtacgtcac ctggatgtcc tggaggatgc
    11161 gggcgatgtg gggccaccag ggctcacccg cgggcgtgtc gaggacgggc gcgaagacgc
    11221 tctgggcgga catcacgtcg ggcgcggcct cggcgagttc gccgaagcac tcctccagga
    11281 cgaaccggtg gtagcggtcg ctctgggcgg cgtgcagcgc gaggccggcc cgggcggcgt
    11341 ccgccggcga ggacgggtgc gcccccggca gccggtcggt gtgggtggcc agttcggtgg
    11401 tgccggcccg gcccgtgaag tagggcacgt tcccggtgtc catcgcgacg cgctcggcct
    11461 caccggcgaa cgcgcgtgcc tcgggcgcca gttggcgggg gaactgcttg agcagcccca
    11521 ggaaccgctc gctctccccg gcgtcgcgca ggtaccgcgg ctgggtggcc gcgtcgagga
    11581 accggccgta caccatcgtc gagcggatca ggcagcgcac gggcaactcg gcgtagcggc
    11641 cgatgacttc ctcgatcgcc cggcgctccc ggacggctcc cagcgcgtcg gtgtacccgg
    11701 cgacgatgtc gcggtagaag cgcacggacg cgagcttctc gtcgccgagc cgcggcacgt
    11761 tctccttgtg ctggtacacg atgggttccc agcgcagccg gagggcgtcc gtgccgccgt
    11821 cctggagggc gctcttcttc atcttgccgg acacctgctc gccgctgacg ccgacgcccg
    11881 ccatgatcac gtcgatcggc gactcgggcc tgacgttcgg gaccagcatg gtggaggcca
    11941 cggacgcctc cacgtggttg ttcagccgct gctccagcga gccgtccccg gtcccggagc
    12001 cgggccggag catcatctcc gtgtcgatca cgcacgggtg ctccccggcg gccagcaggt
    12061 tctcgtcgtg caggtcggac gcgccgatgg cgccgaagag cgcgcacagc gccccgaacc
    12121 ggtagaagta ccgggccggc tggtccgggc cggtcatggc ccgcggcgtg acgaagctct
    12181 gccatccgtg gtcccccacg gacagcgact cgggcacgca tccgcccagg gagtgcgcga
    12241 gatacggatc gaccacggcg tacaggtcgc ggacgaagtc gtcggccgcc agtgtgcgcg
    12301 gtttgaagac cagccgcccg ccgccggcca ggcgcacgcc cacgacgcgc cggttgtcgt
    12361 tgtgggggtc gccgcccgtg gtgatcaacg aggcgagcgt gtcgcccccg tccgtgagca
    12421 gaccgcgctc cacgagccgc ggccggtcgt cgcggaaggc ggtgaacagg tcgtcgtacg
    12481 cgtccaggaa gcggtccagg accacggtga gccgacggcg caggacgtcg tagcggccga
    12541 gcagctctcg gcagttgtcc gggtcctcga tgtggcggcg gaacctgctg atcgcctcgt
    12601 cgctcccggc ggtcgcgggc agcccccggg actgccggaa ctcgtggaac tccccgatga
    12661 gcacccgcag ggagtgcccc tccacggcgg tgacgaggtc ctcccagacc tggtcgacca
    12721 gtgtcccggc gtgctcgggc gcggccgcct gcgagagcgg gccgcgcagc cggtccacga
    12781 cgacctgccg gggaatccgg ttccggtaga acggcaggaa gtcctcgacc gccacctgcg
    12841 gttcggtcac cacgtgtgcg tcggccgccg ccgtcggacc ggttgccggt cgtgcgtcgg
    12901 tcgccacctg tacatcgctc atgcccgctc tcccgccacc agggtccgct ccaggtcgtc
    12961 ctcgccgtac aggtccgcgt acaggtcgcc gtcgcccagg aggctctcgt gcgttcccgc
    13021 ctcggtgatc gtcccgttgt cgaagacgta gatccggtcg gccgacttca ccgtggccag
    13081 gcggtgcgcg atcacgatct gggtggcccc gatctccgag atggcccgca gcacacggcg
    13141 ttcgttgatg ttgtcgagcg ccgccgtggc ctcgtccatc acgaggatct tcgggtcgcc
    13201 cagcagggcg cgcgcgatgg ctatccgctg gcgctgaccg cccgagaagt tggcccccat
    13261 gtcggagacc agggtctggt agcccatcgg cagctcctcg acgaagtcga ggatgcccag
    13321 ccggccgcag aactcccgga cgtactcctc cgacaggtcc ttgcccagcg tgaggttctc
    13381 cagaatggtg cggttgtgca tgtgcacctc ctgggggatg tagccgatgg tgcggcgcaa
    13441 cgcggacctg tcgtactccc cgaggtcgtg gccgccgtac tcgatggtcc cgccggtggc
    13501 ctcgtagagc ccgcagatga tccggccgag ggtgctcttg cccgagcccg acggcccgac
    13561 gagggccacg cgctctcccg cgccgatcgt catcgagacg ttccggacca ccagctcgct
    13621 gtggagcgtg aaccggaagt cgacgttctt cagggtcacg gacggtgcga ccagctcggt
    13681 gcggtcgcct ccggccgcct ccggctcctc gtcggatatc tccgagagcc gggccacgta
    13741 ccgggacacc tcgttgaacg aggtgtacgt ctggaacacc gagttggcca gcgagaagta
    13801 ggtcgcggag atggcctgca cggagacggc cgccccgagc gagatgctgc cgtggctgac
    13861 catgtagagg ctgagcagca gcaggatcag cgggccgaac atctgcgtgg tcgtcgacag
    13921 ccccgcgata cggccctgct gcagacgcat ccgggtccgc atggcgtcca gcgagttgcc
    13981 gtacgtctcg ttccagccgc gcaggaactc ctccgcgtag ccgcccatct tgatggcggg
    14041 gatcgacacg atggcgtcga gctgggtgcc ctggctcttg gccaggtacg cgatctccga
    14101 gtcgacggcc tcggtcaccc ggtaccgcgt cttcatcagg tacagcgcgt tgagcaggaa
    14161 gatgccgacc gcgacggatc ccagccgcca ctcggtgacg agcaggtaca ccgtgacgca
    14221 gagcagggtc cccacgtcga ggacgccctg ggcggtccgg gaggagacca ggtcgcgcac
    14281 cgccgtcacg ctgttgagcc ggtacatcag ttcgcccggc ggccgtgtgg tgaagaactt
    14341 gaacggcagg ttgagcagcc tggtgaacgt ctggctcatc aggtccttgc cgagcacggc
    14401 gatcagcgag gacagcagca cgactctcgt cagatgcagc gcgaggtagc acacggcggc
    14461 cgccagcacg gcggccagga ccacggccgc gtcgccgaaa ccctgccact gcgcgtaccg
    14521 gtcgaccgcc caccgggtga gcacgggaat gccgagcacc gtgccgtaac cgctgagcga
    14581 cagcagcgcc accagggcga tccgcttctt cgtctccgcg gtgatcacca ggaacttgcg
    14641 ccactccgcg aacggcgtgg cgcgcttgcg ctcgaaggtg tcgcccggct cggcggacag
    14701 cacgatctcg gtgaagctct tctccaactc ggcgcggctg atgcgccgtc ggccgaccgc
    14761 ggggtccatg acgaccgcgg tgcggccgtc gaagctctcc aggacgacga agtggtagtt
    14821 ctcccagtac aggatcaccg gtgaggtgaa gttcgcgaga gcggccacgt tccgtacccg
    14881 gtacggcttg acccgcatcc cgcgagattc gaggaactgc gccagctggc tggccgacag
    14941 gccgtcgcgg cccgcctcca tcaccgagcg ggcgctgacg atctcctccg cgcgcccgta
    15001 gtaccgcagc agcgcgatgg acgagcacag gccgcactcc gtctgcgtca cctgcgtcac
    15061 cgtcggcacc cggcgcgccg tgcgcacctt cccccgggtg tccttcttct gggtgtccgt
    15121 cttctgggtc gccgtcgtcg ccgtcacggt caacgccctt ccacggtgag ggtgagcggg
    15181 cacaggcgca gcccggggtc gatccggttg agcaggtgca gggcgagccc cgcgctgccg
    15241 accatcaggc tgttggtgtg cgcgtaccgg ctgtccggat cggccagctt gcgccgcatc
    15301 acctcgggcc ggagccactg gcgctccttc tgccgcacct cgtcgtggag cggactcccg
    15361 tccggccctg cgatgaagcg cagcgcgccg tggttgccca ggtcgccgtg gcaccaggtc
    15421 aggttgcggc cgaagccgag gcgcagggtg ttctcgaccg cctggtcccg ccgggccgcg
    15481 acggtctcgt ggccgagcac gccggcggcg cccgacaggg cgagcgcgac actggtcgcg
    15541 ccgtggcacc agccggtggc gaagctgccc tgccgcgaca gctgggacga ccagttccgc
    15601 tcggcggggt cgtagaacgt gtcgagccgc cggaccaggt cggtcagcgc cgtcccgacc
    15661 ggtgcccggt gctccgccgg cagcaggggg tgggcgcggc cgagggcgtg cacgacgccg
    15721 ctgatgccgt gggcgaagcc ggactggtcc agcaccgacc gggcgagggc gccgtcccgc
    15781 ccgagtgccc gcgtgagcag gagcgcgacc tcggtgacgg cctcgcgccc ctcgggggcc
    15841 gcgactccgc ttccggtggg gtccgcgacg gccgcgaagc agttcagcac gccggcgagg
    15901 ccgctgatga cgtccagcgg cagctcgtcc accggtacgg cgcggatctg ctccaggacc
    15961 aggggcaccg ccccttgggc ggcgctcacc cacgcctcct caccgatgag ccggcccgcc
    16021 gccgagaggc agaacaggat gcccgacatg cccgtgtagc cggcgtatcc ggcctgctgg
    16081 aggctccggg tctcgtagcg gtgcgaggcc aggatctcgc cggtcgtgga gaagatctgc
    16141 cgggccacgg ccaggcagcg ctcgtcgtcc aggacccgtc cggccgcggc gagggtgagg
    16201 gcgatgccgg tccggccggt gtacaggtcg tagccgagca cgccgggcgg ccaggggcgg
    16261 tccgcctccg cggacgcgag cggcccgatc caggtcctgg gcaggtgcgc gaaacggtcg
    16321 ggcagcgagg tcgcgaccag gccgtcggtg agttcgcggg ccagcgaggt gagggccgcg
    16381 cgctcaccgg agtccgcacc gccgccggaa ggggcctcgg tgggccgggc gggcgtgagg
    16441 tggttgtccg ggaactgggc cgtgaacgcc gaacggatga gccgcagttg ctctcccagg
    16501 tcggtctcgc cgaggccggc cgccttgtcg agggcgaggt ccagcgggga ggagccgaac
    16561 gcggcgccca cctcgcggcc gtccccgtcg cagacgcggg tgccggtggc gctgacggtg
    16621 aagtagggga cgtcgcgctc ggccagctgc cgcaactccg aggcgatcag cgtccggtcc
    16681 gaggtcttgc tcgctatggc gatccgcttg agcagcgcga ggtaggtgtc cgtgtcgtcg
    16741 agcgcgctcg gacccgtgac catgcgcagg gtctgggagt agagcgcggt ggggttgtgg
    16801 acgtagcgga tccgcagccc gtcggcggcc ttgcgcagga gcgcggtcca ggtgccgggt
    16861 gccgcgagga ccgcccggta ggtccgggtg aagccgtcgg ccatgctccg gcccaggcgc
    16921 aggatctcct cctcggtccg ctcaccgacc acggtccggc gcgcggacac ctcctgggcc
    16981 ttcagggaga gccggatccg gtccgtgtac ggctcgtcga agctcatctg cttgaacggg
    17041 gacgcgcccc gccccggccc gccgaggaac ccgaggtcga cgtggccgcc ctggtccccc
    17101 cgccggcccg ccatcaccag cggcaggatg cccaccccgt agaccgaccg cccgatcgtg
    17161 ccgtacgcgt tcccgtcggc ctccggcacc ggtccgacgt ggatgcgctc cgggtgcagc
    17221 accgtctcca ggtccaccgg gacgggaccg cggcgggtcg gcacgatgtt ctcgaagtgc
    17281 atgtcccgcg cgttcaacag gtagagcacg gcggccagtt cgccgctctc gtagaggaag
    17341 cgctcggaga tcgcggagac gtcctcggtc tcgacgtact ccacgtatcc gtagccgtcg
    17401 cgggcgagcg ccgtgaccgc gtggagacgg gtgccgaagg ccgcgttgaa ctcgtccgcg
    17461 agcacggcga agcctgcctc gcaggacacg tcgcgcggtt tgtagaccag gcgggtgccg
    17521 gactcgaagg ccaggatgca gacggcccgg ccgtggtggt gggtgtcgcc ctgcggccgg
    17581 ccgaaggaga ccagccggtc ctccaccgcg atgccgaagg tgtcacggat cgccgcacgg
    17641 tcggccacca accgggagca gagttcgacg acggagtcga cggtgccggc cagcaccacc
    17701 ggcgtcaggt tccgcagtac ggggaagtcg aggccgccgg ccgaggcgac cgagccgcgg
    17761 acggcctcgt cgacgaagta ccggtagcgc tcgcgggggg tctctcccag cagggagccc
    17821 tgctcacggg cgtggttcac ggccgcgacc agcggacggg tgtacagctc gcggatccgc
    17881 gcctcggccc ggtcgaggag ttcggtcagc gcgtcgtcgc ggtcggcgaa caggccgggg
    17941 aaggcggcga gcggatcgcc gtccgcggcc cccgccgcga tgtccctgac cacctgctgg
    18001 aacgggtact cctccgcccg cgccgtccag tccttgacga ccccgggcct ggagggcagc
    18061 acggcgggct gctgcggctc acgggagacg accgcgcgga cctcgtcgtc gaaggcagcg
    18121 agcggggtga tggtctcctc gatctcggtg tcgtcgaact ccgggtagta gttgatcgca
    18181 gatctcatgg cccgtctttc cgcccgtgct gtgaagtgac cctgaccccc aaaggacaag
    18241 gcggaatgga cccttggggg tgcttcggtc cattccgcct ggccgattac atcgaccgtg
    18301 cagaactcac gttctgcgtg atcgctccca cccgccgctg accggagggc aggagaatca
    18361 gcactccttg gtgcacttgg tggtcgggca gaaggcgacg ctggccgcca ccgacaccgc
    18421 gacggagacc ggggtggtgc cgccggtcac gtcggcctcg ctcagctcga tgagctcggc
    18481 ctcgtcgtag gcgccgagga agtccttctg gttctcacgc atggtgttcc ctctcgtcgt
    18541 ttcggttggg cggggttcag ctgcagttgg gctggcattc cttggtgagg gtgcaccagc
    18601 cgccgtggtt gcccagcgcg tcggacagag agaaggtgtt cgtggtgcag gcgccgtacg
    18661 cgacgccgtc gaagtcctgc tcctcgatct cttcgatgag ggacaggtcg ccctgataca
    18721 tcaacgttct cccttgtgtc atgggtcgta acgccgcacc ggacttccgt gtcggcgtct
    18781 ggatcccatc ctgggagact gatgttcgac tcccgcatcg cgtcggaggg gatgcgggca
    18841 tcggccgcgc atagggttcg catgcgcggc gcacccgggc ctcgcacgcc ccggtgtcgg
    18901 gcgcccccgg gcctcgcagg cccgcggttt cgggcgcccc cgggcgtcac gcgctcccgg
    18961 tgtcaggcgt cgcggcgccg cagcgcgagg tagccggcgc ccagcgcggc ggccgtccac
    19021 gccgcgagga ccgcgagccc ggaccacgcg ttcagcacgt acccgtcggg cgcgtgccgg
    19081 tagagcgcca gcccgccggc ctggtccggc aggaactgcg cggccctgcc cacgccgggg
    19141 acgttcgtga ggatcgtgga gaccgtgaag aacagcggca tcaggatgcc catggtgagc
    19201 accgaggagc gcaggagagc ggcgacgccc atcgagaaca ggcagagcag ggtggtgaag
    19261 agcacggcgc cgaccagcgc ggccggcaca ccgtcgtcgg tgagcgacac gctctcttcc
    19321 cccatggtcg cctgcgcgag gaagaagctg gtgagcacgg cgacgcagga caccgcaccg
    19381 gcggcgagcc ccccggtgag catcttggcc gcgtagaaca ccccgcgccg cggaaccgcg
    19441 gccagtgaac tgcggatcgt tcccgtggag tactcgctgg tgacggccag caccccgaag
    19501 accacgagac cgatcatccc gagccgcagt ccgctgaacc cggcggagac gggatcgaac
    19561 gacgacggcg cgggctcgtc cgcgtactga cgccgtacga cggctccggt caccaccgcg
    19621 agggcgaggc tgagggcgac gcacagcacg aggctccaca ccatggagcg cacggtgcgc
    19681 accttggacc actcgaagtc gacggccgcg ttcagactgc tcatcaccgt gctgccccct
    19741 gttccgcccg gtactcgacg gaatccgccg tgaactgcat gaaggcgtcc tccagggacg
    19801 cggtcgtcgt ggtcacctcg tagagggcga tccggctctc ggcggccagg gtccccaccg
    19861 tcttctggtc ggtgcccacc gcttcgaggg acccgtcggg cccgtggtcc acctggacgc
    19921 cgcgcgccgc caacaggtcg cgcatgcgct cgggttcggg ggtacggatc aggacgtacg
    19981 accgggagtt gccggtgatg aagtcgtggg cgggagtgtc ggcgaggagc cttccccggc
    20041 cgatcacgat caggtggtcg gcggtcagcg ccatctcgct catcaggtgg ctggagatca
    20101 gcacggcgcg gccctcgccc gccacgcgct tcaccaggtc gcggacccac ttcacgccct
    20161 ccgggtcgag gccgttgacc ggctcgtcga gcagcagggt ctgcggatcg ccgagcaggg
    20221 cggcggcgat gcccaggcgc tgggacatgc ccagggacag ccccttcgcc cgcttgtccg
    20281 ccacgctcgc gagcccgacc gtctccagca gctcgtcgac gcgccgcgcc ggcagccggt
    20341 tgctgcgggc cagcccggcc aggtgccccc gcacgctccg gccgccgtgc accgcgcggg
    20401 cgtcgagcag cgcgcccacg gtggtgaggg gccggggcag gtcctcgtac cgcttgccgt
    20461 cgacgaggac ctcgcccgag gtgggcctgt cgagaccgac catcgcgcgg atcgccgtcg
    20521 atttcccggc gccgttcggg cccaggaacc cggtgacccg tcccggctcg acacggaaac
    20581 tgagcccgtc gaccgctcgg acctttccgt accgtttggt cagttctcgc acttcgatca
    20641 tcgcggtgag tctcctgtgg tgaaccttgc tcgcctggac gtgactgggg acgtgacggt
    20701 ggaggggaca gggggcgggg gaggggggag gggctgtggg catggcggcg ggaccccacc
    20761 gctcgtggaa aagggcgggc gggaagagcg ggcgggtccc ggccgcccgc gggcaggccg
    20821 gccccgcccg gcgccgccgc acgctcacgg gcgcggcggg accaaccggg ttgctgcgcg
    20881 ggtcagtcgg tgttggcgcg gttcagtcgg ttctcgcggg aatcagccgt ctctcgcggg
    20941 ggtcagtcgg ccggccgagc ggtgcgggcc gtcaccgcga tccgctccag cgccgccgcg
    21001 tgccgggcga acgcctcccg tcccttgggt gtgagccgtg cgagtttgcg ccgcccggcc
    21061 gaggccggct gtttgcgcac ttcgatgtac tcctcggccg cgagcgccga caactgcttg
    21121 gacagggccg agtcactcgt accgatcgtg tcccggatga acccgaactc cgtccagtcg
    21181 gcgggcgcca gcagggccac gatcgtcagc cgcggagccg ggtgcaggaa ggcgtcgaag
    21241 tcggcgtcca tcagcggcgc cgatccgccc ggccccgcag ccgggcgtcg gcgacctcgc
    21301 ggacccgggg cgccgccagc aggcagccgc cgaccaccac ggccgcggac aggaggtggg
    21361 gcgtgggcac cccgcccgcg gagagcgccg ctgccagccc ccggaacacc gcgtagccgg
    21421 cgagcccgcc gaccaccccc agcagcacgc cccgggtgcc cggcctgttg cggaccggtg
    21481 caccgtacgt gtgccggagc accagcagcg ccaccaggag cagcccgggg agcagcacgg
    21541 ccccgcccca ggggttgggc aggtcgaagg acgcgaagga gacgaacagc agcagtgcgg
    21601 ccgtcagcag ggacggacgc gacagggcga agcggagttc cgccgcgccg gactgctccc
    21661 gacgggtgcg gatgtcgtcg agtgcggccc gggcgtcggc cggcgtgagg gcgtgttggt
    21721 cgacggcgct tccgtcgtgc tggtcgtcgg tcggcatggg acctcgcacc ttcctgccga
    21781 agggacgtac tttcctaccg agaaagtagc agacagtttc ctgttgggaa agtacactcc
    21841 cggcacggac ccacggggtg acagtgaacg gggaggatct atgaaaccct tgatgctgga
    21901 ggggttgtcg aagcgctttg gcagccaaca agcgctggaa aagctgacgt tggcagtgcg
    21961 gccgggagag ataaccggct tcgtcggcgg caacggagca ggcaagacca ccgccatgcg
    22021 gatcggcgtc ggggtgctcg aaccggacga gggacgggtg ctctggggtg acgcaccggt
    22081 caccagggcg gagacggaac gattcggcta catgccggaa gagcgcgggc tgtaccccaa
    22141 gatgacggtg gcccgccagc tgacctacct cggcgaactc cacggcctct cgcgcgccga
    22201 ggcccgtgac gcgatggtcc gctggacgga gcggctgcgg atcacccagc accgcgacaa
    22261 gcgggtcgcc acgctcagtc tgggcaacca gcagcgcgtc cagctggccg ccgccctggt
    22321 ccacgatccc gacgtactcc tcctggacga gccgttctcg ggcctggacc ccctcgcggt
    22381 ggacgacatg agcgaagtcc tgcgcaccaa ggcggagcag ggcgtgcccg tactcttctc
    22441 cagccaccag ctggacctcg tcgagcagct ctgcgaccgg gtcgcgatcg tgcgcgccgg
    22501 gcgcctcgcg gcctgcggca cgcaccagga gctgcgcccc gcggactcgc gcggacaggt
    22561 gtacgtcgag atcgacggcg ccggcgggga ctggcccgcg gactgcgccg cggccgccgc
    22621 ccaccgggcc cacgaacagg gcgtcctggt cgacctcgcc gcgggccgca ccgagaacga
    22681 cctgctggcg caggcggcac ggcacggcac catacggcag atgcggcggc acgagcccag
    22741 cctcgccgag ctgttccggg acctggtgga accggccgac gacccgccca cggaccgtgg
    22801 agagccggac gccccggcct ccgacccggc tcgtacctcc gacctggaca aggtgtccgc
    22861 atgaagcgcc cgggctccag acagcacacg ctgcgcccca cccgtgtccg actggtgtac
    22921 acccgcgagc tgcgcgcacg catgtgcacc cggggctacg tcgtcggcct cgccctgctc
    22981 tccctcgtca ccttcggcct ggtcatgggc ttcagcatgc tgggcggcac cggcgactcg
    23041 acggtggcgg tgtgcggcgc gccggccgag tcgaccggca ccgcccctcc cggcatacgg
    23101 gtcacgtcct gcgacggcat gaccgacggc cgaaagctcg tcgagaacaa ggacgcggac
    23161 gccgccgtgg tcgtcaccgg caaccgcgcc accctcctct cgcgcgccga caccggcgac
    23221 caggcgaagg cgggagccga ggcactcgcc acgtcgtggg ccggccacca ggccctgctc
    23281 cggcaggacg tggacctgca acgcctggaa cgggacaccg ccgccgccga actcaccacc
    23341 gtgacggtcg gaaagtccgt cggcaccctc cagttgggcg ccgcggcgac gctgatcatc
    23401 gtgctgttca cgcagatcgt gaatcagggg tcggtgatcg cccagggcgt ggtcgaggag
    23461 aagtcgaccc gggtggtcga ggtgctgctg gccacgctca cgccgctgga gctcctcatg
    23521 ggcaaggtcg ccggcatcat cacggccggc atggtgcagg tggcgacgat gctgggcgcc
    23581 gtcgtctgcg gacaggcgct ggtgtccgac acgagcacgg aactgccggg agcgcaggcc
    23641 ctggtggtga cggtgctctg gttcctgctg acgttcgccc tgttcgcctc gctgtacgcg
    23701 gcggccggct ccctggtgtc gcgccccgag gacctgcagg gcgtactcac cccggtgatg
    23761 ctgctcgccc tcgccccggt cggcacggcg acggcagccg ccaccgacct ctccgcgtcc
    23821 tggatctcgg tcgtgcagta catcccgccc ttctccggcc tcctgatgcc gctcaaggcg
    23881 tcggtcggca cggccaacct gcccgagcaa ctgatcgccg ccgcactcct gctggcggcc
    23941 acggtctgct gcatcaccct cgccgcccgc atctacagca actcggtcct cagggtgggc
    24001 gccccggtgc gctggcgcca ggccctggcc gcgtaggccg ccgccggtcc cgggcggtac
    24061 gacgacggtc gcaccgcccg ggaccgtgca gcgcgcccac ccgtcgtaca ccgccgctga
    24121 ggcactgacc ggcacggcgc gcgccgcggc cttcgaacaa accggccgat cgtgcccggt
    24181 tgccggcgtg catgcacgag acgcgaacca ggcccggcac ggggctgctt ccgcccgaag
    24241 acgagtgggt tcaaggcgtt cccgcacgct tgtagccgac ccacaaccgg ccgccgacct
    24301 gcccgagcac ctcgtcgacg acggccacga gaggctccac cctcccgctc agtacctcct
    24361 gcagtccgtg gtggaggcgt gcaccgagcc ccggcacggc cgtctcgagg cgacgtgcca
    24421 gccacttccc gccaccgccc caggacccgg caatcgccag cgccaactcc ccggtccgac
    24481 ggaccagttc gcccgcgatg aacagccgct cgctccggtc ggtgctcccc gcgaggtcgt
    24541 cgaggaggtc ggtgatcgcg tagcggtggt cgtcgatctc ctccgccggc accgggggcg
    24601 gcccggcgtc ggtcagcttc cgggcatgtg cggcgagccg cgccccgagc ccgtcggtgt
    24661 cgaagagcac caggccggcg gcacacatcc acaacagcgg cgaccgccgc gtgggcagct
    24721 cccgatcgat gtaggcgtgc cacgtcgcct cggtgtgcac gaacatctcc accggccagc
    24781 cggcgtactg gaggctctcc cgataggggg ccggtgcccc gtggagcagc accacgatgt
    24841 cgaggtccga cgtcgccgta ccgcgaccgg tggcgacact gccgcccagg aacgcggtac
    24901 gcgcttcggg gtgctgcttc tctacaacgg cgcgcgcggc atcgatccca tccatacccc
    24961 aactatcacc gctgcgcccc gtcgtacgca cgtactttct ctcccccacc ccgccctgcc
    25021 accccgcatc ccccggcagc cgcctcccta ccggctctca aaggccccca ggaaacacct
    25081 cagggacccg acccgcactg cggatcaggc ccctgacctg gtgtttcatc tgtcggggtg
    25141 gcgggatttg agcccacgac ctcgtcgtcc cggatgaggt tcggcagagg ttgcgtccag
    25201 gtggtttggt ctttttcctg gtcaaagcgt tggaggtgag cggcctcagt ggggcgggtg
    25261 tgtggagggc gagcgccgtg ccggatcacg gcacgaacca gaactcactc tcgccgttcg
    25321 cctgtctcgt acagcctcca agcaggccat cgaatggctt cgacttttcc gtcctcactg
    25381 ctcagcaggt tgcgccgatg cagcatgagc cgaaggtggc gagctgcgtc ggagctctct
    25441 tcgactcccc tgtcaagcaa tacagccctc atagtggtgg tgctggtgcc tcccaccaga
    25501 gcgtccaccg gatgcccgtg aacggtctcg cccagcgtga cggtggcccc ctctgccagg
    25561 gagaggatcc ggtacaggcg tttcagcagc acatcgtcat ctccgccacc gaggggtacg
    25621 ccgttccggt ctgcggcctc cagcagcgct gtgcccacgc cgccccggtt ccgccatagt
    25681 tccttgtccc ctaccacgat gaggtggccg cgtgcccggg tgatggcgac gttccacagg
    25741 ttcagctgtc caccgatcca ctcgacggct ccaggatgca tgccttcgcc ggcgacgaga
    25801 gagaacacca tgacatcgcg ttctccgccc tggaaggtgt gcaccgtacc gatgcgcagg
    25861 cgctcctcgt cgtacggtcg cagccgcttg cgtagtgtct cggcctgagc ggtgaacgga
    25921 gtgacaacgc cgacggtggc ctcgagcggg agctgctcca gtagatagcg aacgctgtcc
    25981 tgcactttgc ggatctcgtc ctcattgacc caggagccgc cgaacggcgg gcgggcggcc
    26041 cgcccggtca catccgtcca gatgacagcc gagcgattcg ccagagcagg ccggccgcgg
    26101 gtgtcggtga ggactgtcag cccccccgtc atagaagaag tcgtcccagt actattagtg
    26161 cggcctggtt ccgggccagt tccttctcca gccgctccac ctggcggcgc agcttctcgt
    26221 tctccgcctc ggcagccgac ttcttcggcc tcgccgggcc ggtccgctgg tcgaccagct
    26281 tctccagggc cccggcatcc cgcgcggccc gccactcctt gacgtgcgag tggtacagcc
    26341 gctcgcggcg caggaccgca cccttctcgt tcttgagcgc ggcgtcatac tcggccacga
    26401 tccgcagctt gtactcggga ctgaaggtgc ggcgcttcgg ccgggcagcc gggtcaggtc
    26461 ctgcggggtt ggtactggtc acgtgggggt ggttctcctg tcgtgcccac tcatgctgac
    26521 ccaacgaagc gggacgtctc acccgaggcc ggcagagagg gtccggcgca ggctgagacg
    26581 gcttccggga ggccgacgaa accggtcttc aacggtttga ggctctcaag gctggccaag
    26641 gtgatggtct tctgaagccg acaacgctcg tccaagacgt gagtgggcag gacatagaag
    26701 gtccactggc caaggtccag gggatctagg gtctgcttct cccggtgatg cagaaggcag
    26761 aacacgtaca cgtccgcgct gcgcagtgca tcggctggag tgatgtcggt ccgggcgtcc
    26821 caaccggagg cgggcgcgat gccgaaggag actttcgacg tctgcgactg tgcccacgac
    26881 tgtaggtagg ccgttgactt cacctcgata cgccagttct ggggcgtacg gatgtcaacc
    26941 gcgtcccatt cggtacgggt acccgtggca gcgcccagcg cggtggccac gaggtactcg
    27001 gccagcacgc ctcgcacggt gttgctggtc aggtcggagc acgcccaact ccaaaagtcg
    27061 gcgagcttgc ccaccgtcct gccgttggcg tgtatcaact catcgccgct gcgacgcgcg
    27121 atggccatcg gcccaagctc ggttcccaca cagtcctccg aactatcaag caggtacaga
    27181 gttaaccggg gcgcgatgcg tacgcccgag ccgagaagag gcagaaggcc gctccctggg
    27241 gagtcaccgg gagccggatc ccgaagatca cacccagttg gctcccaaaa ccgggacgca
    27301 aagcaaaaca ggcccggctc tgatctctca gaaccggacc tgacctggtg tttcagctgt
    27361 cggggtggcg ggatttgaac ccacgacctc ttcgtcccga acgaagcgcg ctaccaagct
    27421 gcgccacacc ccgattgtcg ctgctcgtcg cggcgacgtc gtttacttta gcccaccggt
    27481 cgccggagac gaaatccgat tcagcggcgg ccgcggagca gggtggggcg gatgtggtcg
    27541 agggccacga ggagggcggc cacggcgtag agggcgaggc cgatgaggag ggcgttgccg
    27601 aggacgctct tgtaaccgtg ctggtcgacg tccaggaagg ggtagaggta gtgggcctgc
    27661 gtgccgggcg ggtggagctc gccgcgggcc agggagaagg ccaggtaggc cagggggtag
    27721 aggagccagc cgggtgcttg gcgttgacgc agttggccgg gggtggtgaa gaggagccag
    27781 tccagggccg cggccaccgg caccgccgtg tgcaggatgt gggtcgcggc ggtctgccag
    27841 cccgcgccgg tgccgtcccc gtaggtgaag gggctcgtcg ggttggccag gagggcgtgg
    27901 tggacgaggg cggccgcgac gacgtagaag agggtcgcgc cggtgaggga ggccggcagg
    27961 gggtggtggg cggaccacgc gcactgcgcc gaggccagca tcaccagcgc cagcagtatg
    28021 ccgctcagga tcgtgaagtt gctcagggtg tcggccaccg ggccgcccgc ggtcagctcc
    28081 agcgccactc cggtcagggc cagcagggcg atgagggtcc ggaaggccgc gaccgggcgg
    28141 cggcgtacgg ggagcagcac cgctcggggc gggaccacgg tgggcagc
//
