LOCUS       NZ_CP036534            22522 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. VN1 chromosome, complete genome.
ACCESSION   NZ_CP036534
VERSION     NZ_CP036534.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. VN1
  ORGANISM  Streptomyces sp. VN1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8341703)
  AUTHORS   Nguyen,H.T., Pokhrel,A.R., Nguyen,C.T., Pham,V.T.T., Dhakal,D.,
            Lim,H.N., Jung,H.J., Kim,T.S., Yamaguchi,T. and Sohng,J.K.
  TITLE     Streptomyces sp. VN1, a producer of diverse metabolites including
            non-natural furan-type anticancer compound
  JOURNAL   Sci Rep 10 (1), 1756 (2020)
   PUBMED   32019976
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8341703)
  AUTHORS   Pokhrel,A.R., Nguyen,H.T., Dhakal,D., Nguyen,C.T., Pham,V.T.T. and
            Sohng,J.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2019) Department of BT-Convergent Pharmaceutical
            Engineering, Institute of Biomolecule Reconstruction, Sunmoon-Ro221,
            Asan, Chungnam 333-708, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: HGAP3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011650445.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 03:53:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,284
            CDSs (total)                      :: 7,197
            Genes (coding)                    :: 7,083
            CDSs (with protein)               :: 7,083
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 44 of 114
            Pseudo Genes (incomplete)         :: 82 of 114
            Pseudo Genes (internal stop)      :: 3 of 114
            Pseudo Genes (multiple problems)  :: 15 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:32:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2720838
            Orig. end                         :: 2743360
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036534.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jae Kyung Sohng.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22522
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="11"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22522
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22522
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12522](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12522)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(8..21)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    607..623
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.08"
                     /tool="antismash"
     gene            646..2505
                     /locus_tag="EZV63_RS11900"
                     /old_locus_tag="EZV63_12030"
     CDS             646..2505
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028566.1"
                     /locus_tag="EZV63_RS11900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12030"
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="WP_166624106.1"
                     /transl_table=11
                     /translation="MHHSSTAGTGSTAQPSRRTVLIATATAAAVAGTALAAGSGTAYAD
                     ARGPGDDKLRALISRMTLEEKVGQLFVTRVYGHSATDPDQADIDANLEEIGVRTAAELI
                     AEYRVGGVIYFAWAHNTRDPHQIADLSNGIQKASLEQPRGLPVLISTDQEHGAVARVGE
                     PATLFPGAMAVGAGGSRSDARTLGRIAGAELRAMGIRQDYAPDADVNVNPANPVIGVRS
                     FGADPDAVAGLVAAEVTGFQRSGVAACAKHFPGHGDTATDSHTGFPVITHSREQWEELD
                     APPFRAAIEAGIDAIMTAHLMVPALDDSGDPATLSRPILTGILREELGYDGVVVTDSLG
                     MEGVRTKYGDERVPVLALKAGVDQLLNPPDLPLAWNAVLTAVREGELTEARLDESILRV
                     LRLKAKLGLFQDAYTGRRDVERTVGTRAHRAAADRIAERSTTLLVNEGRLLPLSRRAHR
                     RLLVVGADPASPSGTTGPPTGVLADALTELGFTATALSTGTAPSAEVVDRAVAAAGDAD
                     AVVVATYNVTAGSSQRTLVARLLETGKPVVAVAVRNPYDVAQLPGVPAFLAAYSWTDVE
                     VRAAARVIAGRVRPRGRLPVPVVSADDPDTVLYPLGHGLAYRS"
     gene            2709..3356
                     /locus_tag="EZV63_RS11905"
                     /old_locus_tag="EZV63_12035"
     CDS             2709..3356
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140869.1"
                     /locus_tag="EZV63_RS11905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12035"
                     /product="hypothetical protein"
                     /protein_id="WP_166624107.1"
                     /transl_table=11
                     /translation="MRERGAAGVRRALPALGALAAVLLTGCQGAPGEDGGDGERPVSAA
                     TSAGARPSGYGAVFLAVGECASSGTVGFTEVPCDSERAAARVVAREDGRARDGPPCPAT
                     TDFVLHISERRPSADEDGDGNVPRGYACMRGLRPPHPGDPGGGGGPRTVVGDCVRETGD
                     GKVRETACDAEGGEEPRYQVVRTVAERADCPAATVLYVRLGGELPVGCARPL"
     gene            complement(3400..4824)
                     /locus_tag="EZV63_RS11910"
                     /old_locus_tag="EZV63_12040"
     CDS             complement(3400..4824)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070008 - serine-type exopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S28"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449771.1"
                     /locus_tag="EZV63_RS11910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12040"
                     /product="S28 family serine protease"
                     /protein_id="WP_070388155.1"
                     /sec_met_domain="Peptidase_S28 (E-value: 1.1e-08, bitscore:
                     33.0, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKALRWLLALVVLIGTVSTAGAATAAEPKAVDIKDRLLSIPGMS
                     LIEEKPYTGYRFFVLNYTQPVDHRHPSKGTFQQRITVLHKDTDRPTVFYTGGYNVSTTP
                     SRREPTQIVDGNQISMEYRYFTPSRPAPADWSKLDIWQAASDQHRIFQALKPVYSENWI
                     STGGSKGGMTATYYERFYPRDMDGVVAYVAPNDVVNKEDSAYDRFFARVGTEECRDKLN
                     GVQREALVRRAPLEKKYAAYAADNGYTFDTIGSLDRAYEAVVLDYVWGFWQYSTLADCA
                     DIPADAENATDEAIWDSVDTISGFSAYTDQGLETYTPYYYQAGTQLGAPTIHFPHIEKK
                     YVRYGYQPPRNFVPRSIPMKFEPSAMRDVDTWVRHNAHQMLFVYGQNDPWGAEPFRLGH
                     GARDSYVFTAPGMNHGANVAGLVADQKAEATARILDWAGVAPAEVQDDPTAARPLAAFD
                     AKLDKRDVERETALRP"
     misc_feature    complement(4836..4851)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            5213..6370
                     /locus_tag="EZV63_RS11915"
                     /old_locus_tag="EZV63_12045"
     CDS             5213..6370
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="EZV63_RS11915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12045"
                     /product="ATP-binding protein"
                     /protein_id="WP_166624108.1"
                     /transl_table=11
                     /translation="MSAQGPAVRSLERQALLVTVVLRTSSAAVAAVVALLGLGSAASPW
                     WVLSGVAAVLVWAGLFGVRTLRGGPAGRFGAGDVVVCVLLCLLHSRLVPPSVLTASAGT
                     GWIDLVASVTVLNAQCFLRQPHGLLATVVIASTYTAGAPGVREAPVVLLLQGLLSAGMF
                     VLLRRAAHSTDAVLVARAEARANEAAGAAARADERDQQRRLHDTVLATLTMVSTGAITE
                     YSDVLRGRAAADLRVIRALGARADDAADSGHSAAQPARLDAALRTAVFAARPGLPPLTV
                     EFRAAPVLLPGPVATALADAVAEALTNVARHAGTTTARVGAREVGAGAVVEVLDGGSGF
                     DPATVPAHRRGLRESVTGRMAAVGGNASVESRPGAGTRVTLRWPG"
     gene            6367..7533
                     /locus_tag="EZV63_RS11920"
                     /old_locus_tag="EZV63_12050"
     CDS             6367..7533
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EZV63_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EZV63_12050"
                     /product="hypothetical protein"
                     /protein_id="WP_166624109.1"
                     /transl_table=11
                     /translation="MNRGAGPSAGESVAVRYTRVISVVVVLIVAVWHFGYDSLILVRGW
                     SRYEPAWAALASWLVLSAVQLVGSVLLLRGALRGPPAPLLTCVALLAGVVAVAAYPRGG
                     AISDLSWAANTVGWFGVLLLAQRPMRELVALLACTVALTTVALGAHGELGTGEAWARLI
                     AQSYTTAGIQLAFVLLSRELHHAARLTADAARAQADRMARRAAGEALHAERRRRYRYLR
                     DRIAPLLRELAEGRAHPGDEGVRRASAIEAARLRRLFAETEDADHPLLHELRACADVAE
                     RRDVDVTFVCYGELPDLPVAVRRRLTDGPILALASARNTARVTVVVTAGEVTVGVVADA
                     SADAVPRAVRSAGTSVLFDEKENLLWLESRWRLPVPRSTSASSTTTRW"
     gene            7476..8153
                     /locus_tag="EZV63_RS11925"
                     /old_locus_tag="EZV63_12055"
     CDS             7476..8153
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="EZV63_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12055"
                     /product="response regulator transcription factor"
                     /protein_id="WP_031039963.1"
                     /transl_table=11
                     /translation="MAPTGTALDVGIVDDHPVVIDGVRAWLAEEPGIRVGHTGETTADL
                     RAGTVDVLIADLSLDGRLVLSDIAELAAEGRRLVVFSQFTDESLVLDVLNTGVNGFVTK
                     NEGQAHLLHAVRAAAADRPYVPPTTAGVLVSDRSPVAPRLSQQERTSLLWWFQSMSKAS
                     VARRMGVSVHTVDMYIKRARVKYAQVGRPAPTKSDMLARAIEDGLVTPAELAGSAQWRP
                     PAP"
     gene            complement(8181..9035)
                     /locus_tag="EZV63_RS11930"
                     /old_locus_tag="EZV63_12060"
     CDS             complement(8181..9035)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="EZV63_RS11930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12060"
                     /product="ABC transporter permease"
                     /protein_id="WP_224309502.1"
                     /transl_table=11
                     /translation="MLESTTERPGRLAARSPGRRAAEFAALRALIRRETVRLVASPAQA
                     GLTLLNPLLYFVVLGTGLSGMVGSASGGGDYMAYVYPGILMMAVQMPALNAGMSIVRDR
                     ETGLLRAVLVAPVRRDTFLVGKCLGSTVTATAQGGLLLAFAGLAGLPYDPLLLLALLGE
                     LALVAFTLTALVTLAAVRITRIETFQSALGVTMLPLFFLSGAMFSTDGLPVWLAATTLV
                     NPLTYAVDALRQTVAGAVPGGALPTGPDWGGWTPPLAVELLVMCALGVAALVLAARRFS
                     RAG"
     gene            complement(9069..10004)
                     /locus_tag="EZV63_RS11935"
                     /old_locus_tag="EZV63_12065"
     CDS             complement(9069..10004)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123204.1"
                     /locus_tag="EZV63_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12065"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_166624110.1"
                     /transl_table=11
                     /translation="MSAPGSTAIRTRGLRRVYGGTVAVHGLDLTVAAGEKFGFLGPNGA
                     GKSTTIGMLSTLLRPSGGRAAVAGADVAHRPDEVRRRIGVVFQDPSTDRELTGWQNLYF
                     HGRLHGMPRREVRARARSLLDLVGLADRGDAPVGSYSGGMRRRLEVARALMHRPRVLFL
                     DEPTTGLDPQSRSQVWQKLHELGRRDGVTVFLTTHYLEEAENCDRIAVMDHGRLVAQGT
                     PHALKSAIGADVVHLRTDDDRSTARSIRERFGLDAEATPEGVRVGAADGAGWVPRLCAH
                     LTTGVTSVTVTRPSLDDVFLHHTGRSLRNP"
     gene            complement(10001..10372)
                     /locus_tag="EZV63_RS11940"
                     /old_locus_tag="EZV63_12070"
     CDS             complement(10001..10372)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382052.1"
                     /locus_tag="EZV63_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12070"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_224290818.1"
                     /sec_met_domain="PF13471 (E-value: 1.4e-25, bitscore: 88.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPPAVLAAAVARVLTRLPPARLRRVLTFASRGAGPASAAQALRA
                     RNAVVHVSLACAGPRCLQRSVAAALLCRLGGTWPQWCTGVVTEPFGAHAWVAVDGEPVG
                     EADAHARAFHVIMSVPPRR"
     gene            complement(10423..10680)
                     /locus_tag="EZV63_RS11945"
                     /old_locus_tag="EZV63_12075"
     CDS             complement(10423..10680)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385814.1"
                     /locus_tag="EZV63_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12075"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_037767284.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 1.3e-07,
                     bitscore: 30.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.2e-24,
                     bitscore: 84.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3e-12, bitscore: 45.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFALKPGVSLADTEHGTVLLDERSGRYWMLNRTGAVVLRSLLDG
                     ESPQEAARTLLRRYPDAADGAGGHVESLLDALRTAKVIVP"
     aSDomain        complement(10429..10677)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EZV63_RS11945_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="8.40E-27"
                     /identifier="RREFam002.1"
                     /label="EZV63_RS11945"
                     /locus_tag="EZV63_RS11945"
                     /protein_end="84"
                     /protein_start="1"
                     /score="84.0"
                     /tool="antismash"
                     /translation="SFALKPGVSLADTEHGTVLLDERSGRYWMLNRTGAVVLRSLLDGE
                     SPQEAARTLLRRYPDAADGAGGHVESLLDALRTAKVIV"
     aSDomain        complement(10510..10680)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EZV63_RS11945_Lasso_Fused_RRE.1"
                     /evalue="5.10E-10"
                     /identifier="RREFam003.1"
                     /label="EZV63_RS11945"
                     /locus_tag="EZV63_RS11945"
                     /protein_end="57"
                     /protein_start="0"
                     /score="30.3"
                     /tool="antismash"
                     /translation="MSFALKPGVSLADTEHGTVLLDERSGRYWMLNRTGAVVLRSLLDG
                     ESPQEAARTLLR"
     gene            complement(10690..12522)
                     /locus_tag="EZV63_RS11950"
                     /old_locus_tag="EZV63_12080"
     CDS             complement(10690..12522)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981695.1"
                     /locus_tag="EZV63_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12080"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_166624111.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.3e-37, bitscore:
                     129.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFVVLPDHPAGAEVLASVPSPGLPRPKVLEHHSGRPWLVGDWPD
                     DEIVCVGTGPRRLVLLGCAGVDPGALAARLDRARSPADLDDLARLPAGSFHLVASLDGE
                     VRVQGTLSTACQVFYTRAAGVTVAASRAESLAARAGAGIDEERVALELLSPFGPPAPLS
                     EGSVWRGVRSPRIGHCLEIRRDGTARTRRWWTPPEPERRLGDGDFVREALFDAVAARTA
                     GQPTVSADLSGGLDSTSLCFVAARTPGTDLATLHYEGHGGRGEDLAHARRAAEALPQAR
                     HLVVPPTDTPDWYAPFEHTPHDREGPLMFVRARATVEHQAGLVASLGARRHLQGVGGDE
                     LFLPGAMCLHGLLRRDPAAALPHIRALRAKRRWSLATTARTMAASPSYRRWLADEADRL
                     DADRSWGSGASWEIPARLPPWITRDAASTVRRLMREAVAADPEPLAALPVQHEMIWINR
                     VNGTVMRRNSSIGAHAGVTFHAPYTDDRVLEAVLSVRLADRVAATRLKPVLARALDGVV
                     PAGILHRTGKDDASPTLYAGLRRRRGELLDLAEDTRLARMGLIDTAELRRLLLATHADT
                     RPLMPFDPTLACELWLRALPAAGATTAAPSSRTP"
     gene            complement(12688..12810)
                     /locus_tag="EZV63_RS11955"
                     /old_locus_tag="EZV63_12085"
     CDS             complement(12688..12810)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="EZV63_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12085"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_107060642.1"
                     /transl_table=11
                     /translation="MAKEDVYEVPALIEVGDFAELTQLTSQGYWIDSPWGAWWL"
     misc_feature    complement(12804..12818)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.69"
                     /tool="antismash"
     misc_feature    12874..12888
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.14"
                     /tool="antismash"
     gene            complement(13191..16922)
                     /locus_tag="EZV63_RS11960"
                     /old_locus_tag="EZV63_12090"
     CDS             complement(13191..16922)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028569.1"
                     /locus_tag="EZV63_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12090"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_031039944.1"
                     /transl_table=11
                     /translation="MDAQRGWARRLAAYARRHPKDVVLALGASLGGMAVMALVPLITKV
                     IIDDVIGAKARSMAVWAGLLVGAAAVVYVLAYIRRYYGGRLALDVQHDLRTDMYATIMR
                     LDGRRQDELSTGQVVGRATSDLQLIQSLLFMLPMTIGNVLLFLISLGIMAWLSPPLTLI
                     ALAVAPALWFIARRSRTRLHPATWYAQAQAAAVAGVVDGSVGGVRVVKGFGQEEQETGK
                     LREVGRRLFAGRLRTIRLNATYTPALQAVPALGQVAMLALGGWLAVRGHITLGTFVAFS
                     TYLAQLVGPVRMLAMVLTVGQQARAGTERVLELIDTEPAIKDGTKVLPADAPATVEFDD
                     VAFGYDTDGEDGRPVLDGLSFEIRAGETLAVVGSSGSGKSTVSLLLPRFYDVRRGAVLV
                     GGHDVRELTLDSLRAAVGLVPEDSFLFSDTVRANIAYGRPDATDEEVEAAARAAQAHGF
                     IGDLPDGYDTTVGEHGLTLSGGQRQRVALARAILTDPRLLVLDDATSAVDARVEHEIHE
                     ALKQVMRDRTTLLIAHRRSTLGLADRIAVLDRGRLADLGTHEELQERSALYRRLLTDPD
                     ELGGVSPGHTRPAEKLEDTSVRDELDAEFDAERGVTPRLWTGDRTPKDAALAGTPATPE
                     LLARVDALPPADGTPDVDEARAVRPEESYGLRRLLAGFRTPLLISLALVAVDAGTGLLL
                     PVLIRHGIDEGVTQLALGAVWAASLLGLLAVLAQWTAQTGEIRMTGRTGERILYSLRLK
                     IFSQLQRLGLDYYERELTGRIMTRMTTDVDALSTFLQTGLVTAFVSVVTFFGILVALLV
                     IDVQLAFVVFATLPPLIIATYFFRRASVKAYELARERVSTVNADLQESVAGLRIVQAFR
                     REHDGGRRFAERSDGYRQARIRGQWLISVYFPFVQLLSSAAAAAVLIVGGTRIDNATLT
                     TGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLREPASTRTADRPRGVTS
                     LRGEIAFEDVHFRYGDEEEALTGIDLRIPAGQTVAFVGETGAGKSTLVKLVARFYDPTG
                     GRVTADGQDLRALDLTAYRHRLGVVPQEAYLFPGTVRDAIAYGRPDATDAQVEAAARAV
                     GAHEMIATLTGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLLLDEATAALDLATE
                     AQVNHATDRIAGRRTTLVVAHRLTTAARADRVVVMADGRVAEDGTHDELLALDGRYARL
                     WRTFVGAAEPEEPVGAAH"
     misc_feature    complement(16993..17010)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.89"
                     /tool="antismash"
     gene            complement(17041..18060)
                     /locus_tag="EZV63_RS11965"
                     /old_locus_tag="EZV63_12095"
     CDS             complement(17041..18060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065746.1"
                     /locus_tag="EZV63_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12095"
                     /product="esterase-like activity of phytase family protein"
                     /protein_id="WP_166624112.1"
                     /transl_table=11
                     /translation="MRPRILRTALAALTAGLAAAGCLTAAGPAAAQGSSPGNSQRNACS
                     RSVSLAGFSDVLDKTTYDGTYVGNLSALAPDRRGTVAALADRSSLFRLDARTLQPRGVI
                     PLADEEGAALDSEGLVVDRDGTYLVSSETEPSVRRYSRTGEILGRLPVPDDLRTAPEGR
                     AQENGSFEGLTLLPGGRTLLASMEYQLDGDPADLVRLQTWQRTRDGGFRLGDRYTYRTD
                     AGLGVSEVTALPDGRLLVLERGFTSGVGNTIRLHLADRPGRGTPRGTPLPKRLLADLAD
                     CPSLGATAGQPQPNPLLDNFEGMAVTGRSRDRTDVLIVSDDNQNDVQTTRFLRLRVRT"
     gene            complement(18259..18921)
                     /locus_tag="EZV63_RS11970"
                     /old_locus_tag="EZV63_12100"
     CDS             complement(18259..18921)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978002.1"
                     /locus_tag="EZV63_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12100"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_031039937.1"
                     /transl_table=11
                     /translation="MKSVDDVREAGGADRERAGAVAGAVPAGKHAGGRRPGETRTREAI
                     LDAARACFAERGFDATSMRRIAEAAEVDQSLVHHFYGTKENLFLQALEVPLKMPQALAA
                     AAEGGREGVGERMVRAHLALWDDLSTRPALMTMVRSASVHRVAAARLRETATTILADAL
                     GNVVTGEDAVLRSNLIATQLIGLAMMRYIAVLEPLAAADTDTVVRYYGPALQAIVEG"
     misc_feature    18989..19002
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.14"
                     /tool="antismash"
     gene            19056..20090
                     /locus_tag="EZV63_RS11975"
                     /old_locus_tag="EZV63_12105"
     CDS             19056..20090
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978003.1"
                     /locus_tag="EZV63_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12105"
                     /product="hypothetical protein"
                     /protein_id="WP_166624113.1"
                     /transl_table=11
                     /translation="MSTNLTTSAASEPDGGASSAPPPGGRKPVIRLAAIVVGLTAAITV
                     MLCAFALPSVNGGPHHAPLGVTGPAAQSVQAKLDGDAWDVTVYDDAEALTDAIEDRDAV
                     GGIALGSDGVTVLTATAGGQLISTAIGGLGETLAEQQHVSATVRDLVPFPADDPRGTGL
                     TGAALPMVFGGMLPAIVLLQVFPGHARLRTRLAGVVAFALAAGVAVSAVLTYGTGTLDG
                     NFWITSLGLALGMAALAVPFLGLESLFGFAGFGAGAAVTMFLGNPLSGLPTGPYWLPDG
                     WSTFGQLLPPGASGSLLRANAYFDGTGAGGPALVLTAWAAVGLVLMLAADRRNRRKGAA
                     RPAV"
     gene            20198..22492
                     /locus_tag="EZV63_RS11980"
                     /old_locus_tag="EZV63_12110"
     CDS             20198..22492
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325523.1"
                     /locus_tag="EZV63_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_12110"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_166624114.1"
                     /transl_table=11
                     /translation="MTSSATAPPHAATEPPAPSPADAPPRWSRPALLAILVLAAGLYAW
                     NLSGSGLNSFYSAAVLSGTESWKAWFFGSLDAGNFLTVDKPPLALMVMGLSCRLFGYGT
                     WQMMLPLIGAALATIWILHASVRRVWGHGAAAVAALVLALTPITVAINRDNNPDTLLVF
                     LMVAGAALGLRATRDGRLLPLLGSAVCFGLAFNTKMLQGWIALPAVFLVYVYASDLGWA
                     KRVRNLALAAVALAVASFWWAAAVSLVPASERPYIGGSTDGTAWDLILGYNGLGRILGG
                     DGNMGGGGGAGGGGGFSGTAGIGRMFNDVLGGQISWLLPFAGIALAGGLVLCGRAPRTD
                     LTRAALVLWGGWTVLHYLTFSMAEGTMHPYYTTALAPGIAALCGGGGVMLLRAFRADRR
                     WVWVLPLALGVTGLWAVVLLRRASGWNTWLWPSVAVVMALAVAGLLVFRSGRRVRLLAV
                     SVAAAVVAGIAGPAAYAWSVPSGSGGGMGGTNPTAGPSTGGGMGGPGFGGGGRGGAPGG
                     GEGAPGGGGQGGQPQGGGRGGPGGGSFPGGGSAPDGGPAPGGGDGRASEGAGDSTGTAP
                     EGSGAGTDGQQGSTGGSGGDGGGGGMGGPGGGGGGGMGGASTELVAYLKKHQDGAKWLL
                     AVSSSQSAAQLILSSGEPVISMWGWSGSDNAMTLARLKELVQKGELHYVQVGGGMGGGP
                     GGGDGLSSQVTEWIQEHGTAVDESEYGGTSTDASDSESQSDSQSGSQSGSQGSQSDSAS
                     GLYRLDPADVD"
ORIGIN
        1 gcaggcgtcg atcggggacg acctgtgcga cctgctggtc ccgaaggggc accgcttcgc
       61 ggggcgggcg gccgtgcggc gggcggagct gggcggcgag cggtggatct gccagccgcc
      121 cggccgggtc tgccacgact ggctgatgcg gaccctgcgc ggcgccgggc acgagccgga
      181 catcgtccac caggcggacg agaacccgac gctcgtggcg ctggtggcgg ccgggctggg
      241 catcgccctc atcccccggc tggggcgcgg gccgctgccg gacggcgtgg tggaggtggc
      301 gctcgaaccg atgccggtac ggcggctgta cgcgctgtgg cgcacgggcg cggcacgccg
      361 cccggcgatc gcggaaacgg tccgcaccct gcgcgcccac tggccggccg cctcgaccca
      421 cgccgccccg gcgacgacaa gtgcggtccg ctccggccgc cccgccgcgc acccggcctg
      481 acccgccgat cgccgcccgg cgacggcgcc cggccgcacg ccgtcgccgg gcgtcgcgac
      541 accacggccg ggccactcgt gtgcggtccc ttgactggca gaaaccttcc ggatattgct
      601 gattccttgg aagtttcctt caccagccct ccggaaggag cgcacgtgca ccacagcagc
      661 acggccggca cgggaagcac cgcacagccc tccagacgca ccgtcctcat cgccaccgcc
      721 accgccgccg cggtcgccgg cacggccctc gcggccggga gcggcaccgc gtacgccgac
      781 gcccgcgggc ccggcgacga caagctgcgt gccctgatct cccgcatgac gctggaggag
      841 aaggtcgggc agctcttcgt cacccgggtc tacggccact ccgccaccga ccccgaccag
      901 gccgacatcg acgccaacct ggaggagatc ggcgtccgca ccgcggccga gctgatcgcc
      961 gagtaccggg tcggcggcgt catctacttc gcctgggcgc acaacacccg cgacccgcac
     1021 cagatcgccg acctctccaa cggcatccag aaggcgtccc tggaacagcc gcgcggcctc
     1081 cccgtgctga tctcgaccga ccaggagcac ggcgcggtgg cccgcgtggg cgagcccgcc
     1141 accctcttcc cgggggcgat ggccgtcggc gccggcggct cgcgctccga cgcccgcacc
     1201 ctcggccgga tcgcgggcgc cgagctgcgc gcgatgggca tccggcagga ctacgccccc
     1261 gacgccgacg tgaacgtcaa cccggccaat ccggtgatcg gcgtacggtc cttcggcgcc
     1321 gaccccgatg ccgtggccgg gctggtggcg gccgaggtga cggggttcca gcggtccggg
     1381 gtcgccgcgt gcgccaagca cttccccggg cacggcgaca ccgccaccga cagccacacc
     1441 ggcttcccgg tgatcacgca cagccgcgag cagtgggagg agctggacgc accgcccttc
     1501 cgcgcggcga tcgaggccgg tatcgacgcg atcatgaccg cgcacctgat ggtccccgcg
     1561 ctcgacgact ccggcgaccc ggccaccctc tcccgtccca tcctcaccgg catcctccgc
     1621 gaggagctgg gctacgacgg ggtcgtggtc accgactccc tcggcatgga gggcgtacgg
     1681 accaagtacg gcgacgagcg cgtgcccgtg ctggcgctga aggcgggcgt cgaccagctg
     1741 ctcaacccgc cggacctgcc gctcgcctgg aacgcggtcc tgaccgccgt acgggagggc
     1801 gaactcaccg aggcgcggct cgatgaatcg atcctgcgcg tgctgcggct gaaggcgaag
     1861 ctgggtctct tccaggacgc gtacaccggt cgccgggacg tcgagcggac cgtcggcacc
     1921 cgggcccacc gggccgcggc cgaccggatc gccgagcgga gcaccacgct gctggtcaac
     1981 gagggtcgcc tgctgccgct ctcgcgccgg gcgcaccgca ggctgctggt ggtgggcgcc
     2041 gacccggcct cgccctcggg cacgaccggg ccgcccaccg gcgtcctcgc ggacgccctg
     2101 acggagctgg gcttcacggc caccgccctg tccaccggca ccgcgccctc cgccgaggtc
     2161 gtcgaccggg ccgtcgcggc ggccggggac gccgacgcgg tggtcgtcgc cacgtacaac
     2221 gtcaccgcgg gcagcagtca gcgcaccctg gtcgctcggc tgctggagac cgggaagccc
     2281 gtcgtcgcgg tcgccgtccg caacccgtac gacgtcgccc agctccccgg tgtgcccgcc
     2341 ttcctcgccg cctactcctg gacggacgtc gaggtgcggg cggcggcccg ggtgatcgcc
     2401 ggacgggtgc ggccccgcgg gaggctgccg gtgccggtgg tctccgcgga cgacccggac
     2461 acggtgctct acccgctggg acacggcctg gcctaccggt cgtagccggc gcggcgggta
     2521 cgcacagccg ccgcggccgg tactcgtcgc ggtcgcggcc ggtcctcgca gccgtcgcgg
     2581 ccggtcggag cgcgggctgc gacgcgcgcc ggggggtgcc ccggcgctcc tgcccgaagc
     2641 atcccgcgcg tctggcgtgc gcccgctccg gcgggccacg ctggacgggg gatccggtgg
     2701 ggggcgcaat gcgtgagcga ggggccgcgg gagtgcggcg ggcactgccg gcgctggggg
     2761 cgctggcggc ggtgctgctg acgggctgcc agggggcgcc cggcgaggac ggcggtgacg
     2821 gggaacggcc ggtgtcggcg gcgacgtccg ccggggcgcg gccgtccggg tacggggcgg
     2881 tgttcctggc ggtcggcgag tgcgcttcgt cggggacggt cggcttcacc gaggtgccgt
     2941 gcgacagcga gcgggcggcg gcgcgggtcg tcgcccggga ggacggccgt gcgagggacg
     3001 ggccgccgtg ccccgccacc accgacttcg tcctgcacat cagtgagcgg cgcccgtccg
     3061 cggacgagga cggcgacggg aacgtgcccc gcggatacgc ctgcatgcgc gggctccggc
     3121 cgccgcaccc cggcgacccg ggcggcgggg gcggcccgcg caccgtcgtc ggcgactgcg
     3181 tgcgcgagac cggggacggc aaggtgcgcg agaccgcctg cgacgcggag ggcggggagg
     3241 agccgcggta ccaggtcgtc cggacggtcg ccgagcgcgc cgactgcccg gccgccaccg
     3301 tcctgtacgt ccgcctgggc ggcgagctgc cggtgggctg tgcccggccg ctgtgagcgg
     3361 cggccgggca cagcccacgg gtgtgacgcg gtggcggtgc tacgggcgca gcgccgtctc
     3421 ccgctcgacg tccctcttgt ccagcttggc gtcgaaggcc gccagcggcc tggccgccgt
     3481 cgggtcgtcc tggacctcgg cgggtgcgac gcccgcccag tcgaggatgc gggccgtggc
     3541 ctcggccttc tggtcggcca ccagaccggc gacgttggcg ccgtggttca tgccgggcgc
     3601 ggtgaacacg taggagtcgc gcgcgccgtg gccgagtcgg aacggctcgg cgccccacgg
     3661 gtcgttctgg ccgtacacga acagcatctg gtgggcgttg tgccgcaccc acgtgtcgac
     3721 gtcccgcatc gccgacggct cgaacttcat cgggatcgag cggggcacga agttgcgcgg
     3781 cggctggtag ccgtagcgga cgtacttctt ctcgatgtgc gggaagtgga tcgtcggcgc
     3841 gcccagctgg gtgcccgcct ggtagtagta cggcgtgtac gtctccaggc cctggtcggt
     3901 gtaggcggag aagccggaga tcgtgtcgac ggagtcccag atcgcctcgt cggtggcgtt
     3961 ctcggcgtcg gccgggatgt ccgcgcagtc ggcgagggtg ctgtactgcc agaagcccca
     4021 cacgtagtcg aggacgacgg cctcgtaggc gcggtcgagg ctgccgatgg tgtcgaaggt
     4081 gtagccgttg tcggccgcgt acgccgcgta cttcttctcc agcggcgccc ggcgcaccag
     4141 cgcctcgcgc tgcacgccgt tgagcttgtc gcggcactcc tccgtcccga cgcgggcgaa
     4201 gaagcggtcg taggccgagt cctccttgtt caccacgtcg ttgggggcga cgtaggcgac
     4261 gacgccgtcc atgtcacgcg ggtagaagcg ctcgtagtag gtggcggtca tgccgccctt
     4321 ggagccgccg gtggagatcc agttctccga gtagacgggc ttcagcgcct ggaagatgcg
     4381 gtgctggtcg ctggcggcct gccagatgtc cagcttggac cagtcggccg gcgcgggccg
     4441 cgacggggtg aagtagcggt actccatgga gatctggttg ccgtccacga tctgcgtcgg
     4501 ctcgcgccgg ctgggggtcg tggagacgtt gtagccgccg gtgtagaaga ccgtcgggcg
     4561 gtcggtgtcc ttgtgcagca cggtgatccg ctgctggaac gtgcccttgg acgggtgccg
     4621 gtggtcgacc ggctgggtgt agttgaggac gaagaagcgg tagccggtgt acggcttctc
     4681 ctcgatcagg ctcatgcccg gtatggacag cagccggtcc ttgatgtcga cggccttcgg
     4741 ctcggcggct gttgccgcgc ccgccgtgct gacggtgcct atcagcacca cgagcgccag
     4801 cagccatctg agcgccttgc gcatgcaccc tccctgtgaa acagatgtcc gccggaagct
     4861 atcggagcaa gtcgcgcgga caccaggggt gacgggaaga taccgccggc cgtcgtgggt
     4921 ccgcggcggt gcaggactga ccaagtcccg tgcacccgtg acacattccg gggcccgcgg
     4981 tgcccttagg gtccacgggc gggactctca ctgacacggg accacggacc tgaaggatca
     5041 cgtcgtgcga tcagcggacc acagacactc cggcgcggtc gcggcagcag cccggcggcg
     5101 tctcgaccga gccggctgag ccgcgtccga cggcatggga cgcaccccgg actccgccac
     5161 ggccgcccct cccctcctgc ctctcccgct cctcccgccg tcaggggcgg cggtgtccgc
     5221 ccaggggccc gccgtacgca gcctggagcg tcaggcgctg ctggtcaccg tggtcctgcg
     5281 gacgtcgagt gcggcggtgg ccgcggtggt ggcgctcctg gggctgggat cggcggcgag
     5341 tccgtggtgg gtgctgtcgg gcgtcgccgc ggtgctggtg tgggcgggcc tgttcggcgt
     5401 ccgcaccctg cgcgggggcc cggccggccg gttcggtgcc ggtgacgtcg tggtctgcgt
     5461 cctgctctgc ctgctccatt cccggctggt gcctccctcg gtgctgacgg cgtcggccgg
     5521 caccgggtgg atcgacctcg tggccagcgt caccgtgctc aacgcgcagt gcttcctgcg
     5581 ccagccccac ggactgctcg cgaccgtcgt gatcgcctcg acctacacgg ccggcgcccc
     5641 cggagtgcgg gaggcgcccg tcgtgctgct gctccagggc ctgctgagcg ccgggatgtt
     5701 cgtcctgctg cgccgcgccg cgcactcgac ggacgccgta ctggtggcca gggcggaggc
     5761 gcgcgcgaac gaggcggccg gggcggcggc ccgggcggac gagcgcgacc agcagcggcg
     5821 cctgcacgac acggtgctcg ccaccctcac catggtgagc accggtgcga tcaccgagta
     5881 ctccgacgtg ctgcggggcc gtgccgcggc cgacctccgg gtcatccggg cgctcggtgc
     5941 ccgtgcggac gacgcggcgg actccgggca ctcggccgcg cagccggccc ggctggacgc
     6001 ggcgctgcgc accgcggtct tcgccgcgcg gcccggactg cccccgctga ccgtggagtt
     6061 cagggccgcg ccggtgctgc tgcccggtcc ggtcgcgacc gcgctggcgg acgccgtcgc
     6121 ggaggccctg acgaacgtcg cccggcacgc cggcaccacc acggcccggg tgggtgcgcg
     6181 agaggtcggg gccggtgcgg tcgtggaggt cctggacggg gggagcggct tcgaccccgc
     6241 gaccgtgccc gcgcaccgca ggggcctgcg ggagtcggtc accggccgga tggcggccgt
     6301 gggcgggaac gcgtccgtcg agtcccggcc gggcgccggg acccgcgtca cgctgcggtg
     6361 gcccgggtga acaggggtgc gggcccctcc gcgggcgagt cggtcgcggt ccggtacacg
     6421 cgggtgatca gcgtcgtggt cgtgctcatc gtcgccgtct ggcacttcgg ctacgactcg
     6481 ctgatcctgg tgcgcggctg gtcgcggtac gagccggcct gggcggccct ggcctcctgg
     6541 ctggtgctct ccgccgtcca gctggtcggc tccgtcctcc tgctgcgggg cgcgttgcgc
     6601 ggcccgccgg ccccgctcct gacgtgcgtc gcgctgctgg ccggcgtcgt ggccgtcgcg
     6661 gcgtatccgc ggggcggggc gatcagcgac ctcagctggg ccgcgaacac ggtgggctgg
     6721 ttcggcgtac tgcttctggc gcagcgcccg atgcgtgagc tggtcgccct gctggcctgc
     6781 accgtcgcgc tgacgaccgt ggcgctcggg gcgcacggcg aactcggcac cggtgaggcc
     6841 tgggcccgcc tgatcgccca gtcctacacc acggccggta tccaactcgc cttcgtcctg
     6901 ctcagccggg agctgcacca cgccgcccgg ctcaccgccg acgcggctcg ggcgcaggcc
     6961 gaccgcatgg cgcggcgggc ggccggggag gccctgcacg cggagcggcg gcgccggtac
     7021 cgctacctgc gcgaccggat cgcaccgctg ctgcgcgagc tggccgaggg ccgggcgcat
     7081 ccgggggacg agggcgtgcg gcgggcgagc gcgatcgagg cggcgcggct gcgcaggctg
     7141 ttcgccgaga cggaggacgc ggaccatccg ctgctgcacg agctgcgggc ctgcgccgat
     7201 gtcgccgaac gccgcgacgt ggacgtcacg ttcgtctgct acggggagct gcccgacctc
     7261 cccgtggcgg tgcgccggcg gctgacggac ggcccgatcc tggccctcgc gtcggcgcgg
     7321 aacaccgccc gggtcacggt cgtcgtgacg gccggcgagg tgacggtggg cgtggtggcc
     7381 gacgcgtcgg ccgacgcggt gccgcgtgcc gtccggtccg ccggcacatc ggtgctgttc
     7441 gacgagaagg agaacctgtt gtggctggaa tcccgatggc gcctaccggt accgcgctcg
     7501 acgtcggcat cgtcgacgac cacccggtgg tgatcgacgg cgtccgggcc tggctggccg
     7561 aggagccggg catccgtgtc ggacacaccg gcgagaccac ggcggacctg cgcgccggca
     7621 cggtggacgt gctgatcgcg gacctcagcc tcgacggccg gctggtgctg tcggacatcg
     7681 ccgaactcgc cgcggagggc cggcggctgg tcgtcttctc ccagttcacc gacgagtcgc
     7741 tggtgctgga cgtactgaac acgggcgtca acgggttcgt caccaagaac gagggccagg
     7801 cccatctgct gcacgccgta cgggccgccg cggcggaccg cccctacgtg ccgccgacca
     7861 cggcgggcgt tctggtctcg gaccgcagcc cggtggcgcc ccggctgtcc cagcaggagc
     7921 ggacgtcgct gctgtggtgg ttccagtcca tgtccaaggc gtcagtggcc cgccgcatgg
     7981 gcgtgtccgt gcacaccgtg gacatgtaca tcaagcgggc ccgggtcaag tacgcccagg
     8041 tcggcaggcc cgcaccgacg aagtccgaca tgctggcccg cgcgatcgag gacggcctgg
     8101 tcacccccgc cgaactggcg ggctccgcgc agtggagacc gccggcgccg tgacgcccgc
     8161 ccctgtccct ccccctcccc ctaaccggca cgggagaagc ggcgggccgc cagcaccagg
     8221 gcggcgacgc ccagagcgca catcaccagc agctcgacgg ccagcggcgg tgtccagccg
     8281 ccccagtcgg gcccggtcgg gagcgcaccg cccggcacgg ccccggccac ggtctgccgc
     8341 agcgcgtcca cggcgtaggt cagcgggttg acgagcgtcg tcgcggccag ccacaccggc
     8401 aggccgtccg tcgagaacat ggcacccgac aggaagaaca gcggcagcat ggtcaccccg
     8461 agcgccgact ggaacgtctc gatccgggtg atgcggacgg ccgccagggt cacgagcgcg
     8521 gtcagggtga acgccaccag cgccagttcg ccgagcaggg cgaggagcag cagcgggtcg
     8581 tagggcaggc cggcgagtcc ggcgaacgcg agcagcaggc cgccctgggc ggtcgccgtc
     8641 acggtgctgc cgaggcactt gccgaccagg aaggtgtcgc gccggaccgg tgcgaccagc
     8701 acggcgcgca gcagccccgt ctcgcggtcg cggacgatgg acatccccgc gttcagcgcg
     8761 ggcatctgca cggccatcat caggatcccc gggtagacgt aggccatgta gtccccgccg
     8821 ccggacgcgg agccgaccat gccgctcagt ccggtcccga ggaccacgaa gtagagcagc
     8881 gggttcagca gcgtcaggcc cgcctgggcg gggctcgcga ccagccggac cgtctcccgc
     8941 cggatcagtg cccgcagtgc ggcgaactct gcggcgcgcc ggccgggcga ccgcgccgcg
     9001 agccggccgg gtcgctccgt ggtggactcc agcacgtcgg ttccttccct cgtcctcgtg
     9061 tccggccgct acggattgcg cagggagcgg ccggtgtggt gcaggaaaac gtcgtccagg
     9121 ctgggtctcg tcacggtcac cgacgtgacg cccgtggtca ggtgggcgca gagccgcgga
     9181 acccagcccg ccccgtccgc cgcgccgacc cgcacgccct ccggcgtcgc ctcggcgtcc
     9241 agaccgaacc gctcgcggat cgaccgggcc gtgctgcggt cgtcgtccgt ccgcaggtgc
     9301 acgacgtcgg cgccgatcgc cgacttgagt gcgtggggcg tcccctgcgc caccaggcgg
     9361 ccgtggtcca tcaccgcgat ccggtcgcag ttctcggcct cctccaggta gtgcgtggtc
     9421 aggaagacgg tcacgccgtc gcgccggccc agctcgtgca gtttctgcca gacctgggac
     9481 cggctctgcg ggtcgagtcc ggtcgtcggc tcgtcgagga acagcacccg cggccggtgc
     9541 atcagggcgc gggccacctc cagccggcgc cgcatgccgc cggagtagga gccgacgggc
     9601 gcgtcgcccc ggtcggcgag gcccaccagg tcgagcagcg aacgggcccg ggcgcgcacc
     9661 tcgcgtcgcg gcatgccgtg caggcgcccg tggaagtaca ggttctgcca cccggtcagt
     9721 tcacggtcgg tggaggggtc ctggaagacg acgccgatcc tgcgcctgac ctcgtcgggg
     9781 cggtgcgcga cgtccgctcc cgccacggcc gcccgcccgc cgctgggacg caggagagtg
     9841 gagagcatgc cgatggtggt ggacttgccc gcgccgttgg ggccgaggaa gccgaacttc
     9901 tcccccgcgg ccaccgtcag gtcgagtccg tgcacggcca cggtgccgcc gtagacgcgc
     9961 cgcaggccgc gggtgcggat cgccgtggag ccgggggcgc tcaccggcgg ggcggtacgg
    10021 acatgatgac gtggaaggcg cgcgcgtgtg cgtcggcctc gcccacgggc tcgccgtcca
    10081 cggccaccca ggcgtgtgcc ccgaagggct ccgtgaccac accggtgcac cactggggcc
    10141 aggtgccgcc cagccggcac agcagcgcgg cggcgacgga ccgttgcaga cagcgcggac
    10201 cggcgcaggc caggctcacg tgcaccacgg cgttgcgcgc ccgcagcgcc tgcgccgcgc
    10261 tcgcggggcc cgcgccccgg ctcgcgaacg tcagtacgcg gcgcagccgg gccggaggca
    10321 gccgggtcag cacgcgtgcc accgcggcgg cgagtacggc gggcgggcgc agcggccagg
    10381 gcggggggtc cgcggactcc aggcgcaggg tggtgccccc gctcacggga cgatcacctt
    10441 ggccgtgcgc agggcgtcga gcaggctctc tacgtggccg ccggccccgt cggccgcgtc
    10501 ggggtagcga cgcagcagcg tccgcgccgc ctcctgcggc gactcgccgt ccagcagaga
    10561 gcgcaggacg acggcaccgg tgcggttcag catccagtag cgcccgctgc gttcgtcgag
    10621 caggacggtg ccgtgctcgg tgtcggcgag ggacaccccg ggcttcaggg cgaaggacat
    10681 cgggcctcct tatggcgttc gggacgaggg ggcggcggtg gtcgcgcccg ccgcgggcag
    10741 ggcccgcagc cacaactcgc aggcgagggt cgggtcgaag ggcatcagcg gccgggtgtc
    10801 ggcgtgcgtg gcgagcagca gccggcgcag ctccgccgtg tcgatcagac ccatgcgggc
    10861 caggcgcgtg tcctcggcga ggtcgagcag ttcaccgcgg cgccggcgca ggcccgcgta
    10921 gagggtgggg ctggcgtcgt ccttgccggt gcggtgcagg atcccggccg gtacgacgcc
    10981 gtccagggcc cgtgcgagca ccggcttgag ccgggtcgcg gcgacccggt cggccagccg
    11041 cacggacagg accgcctcca gtacccggtc gtcggtgtag ggggcgtgga aggtgacgcc
    11101 cgcgtgggcg ccgatgctcg aattgcggcg catcaccgtg ccgttgaccc ggttgatcca
    11161 gatcatctcg tgctgcaccg gcagcgcggc cagcggttcg gggtccgccg cgaccgcctc
    11221 gcgcatcagg cggcgtacgg tcgacgcggc gtcccgggtg atccagggcg gcagcctggc
    11281 cgggatttcc caggaggcgc ccgagcccca ggaccggtcc gcgtcgagcc ggtccgcctc
    11341 gtcggccagc cagcggcggt aggacggcga ggccgccatc gtgcgcgccg tcgtggcgag
    11401 cgaccagcgg cgcttggcgc gcagcgcgcg gatgtgcggc agcgcggccg ccgggtcgcg
    11461 gcggagcagt ccgtgcaggc acatcgctcc cggcaggaac agttcgtcgc cgccgacgcc
    11521 ctggaggtgg cggcgcgcgc ccagggaggc gacgaggccg gcctggtgct cgacggtggc
    11581 cctggcccgg acgaacatca acgggccctc ccggtcgtgc ggggtgtgct cgaacggcgc
    11641 gtaccagtcc ggcgtgtccg tcggcggcac cacgaggtgc cgggcttgcg gcagcgcttc
    11701 cgcggcccgg cgggcgtggg ccaggtcctc gccccggccg ccgtgtccct cgtagtgcag
    11761 ggtggccagg tccgtgccgg gggtgcgggc ggcgacgaag cagaggctcg tcgagtccag
    11821 gccgccggag aggtcggcgc tcaccgtcgg ctggcccgcg gtccgtgccg cgacggcgtc
    11881 gaacagtgct tcgcgcacga agtcgccgtc gccgagccgg cgttcgggct cgggcggggt
    11941 ccaccagcgc cgggtacggg cggtgccgtc gcggcggatc tccaggcagt gcccgatgcg
    12001 ggggctgcgc acgccgcgcc acaccgaccc ctcgctgagc ggcgcgggcg ggccgaacgg
    12061 ggacagcagt tcgagggcga cgcgttcctc gtcgatgccc gcgccggcgc gggcggcgag
    12121 gctctcggcc cgggaggccg ccaccgtgac accggcggcc cgggtgtaga agacctggca
    12181 cgcggtggac agggtgccct ggacccgcac ttcgccgtcg agcgaggcga ccaggtggaa
    12241 gctgccggcg ggcaggcggg cgaggtcgtc caggtccgcc ggggaccggg cccggtccag
    12301 ccgggccgcc agggccccgg ggtcgactcc cgcgcaaccg agcagcacca ggcggcgcgg
    12361 accagtgccg acgcacacga tctcgtcgtc cggccagtcg cccacgagcc aggggcgccc
    12421 ggagtggtgc tccagcacct tggggcgcgg cagcccggga gacggcaccg atgcgaggac
    12481 ctcggcaccg gccggatggt cgggaagtac cacgaactcc atgcgtatcc tccaccggag
    12541 tgccgagggg gcggcccggc cggcgtgtgg agtcggccgg acctctcccc cgatgtggag
    12601 tgaccgggaa gcggacggcc ggtgcgtggg actgctgctc cggcgccgct tcccgcgtca
    12661 cccggccccg tggggcctac gggtggctca gagccaccag gcgccccacg ggctgtcgat
    12721 ccagtagccc tgggacgtca gctgggtgag ctcggcgaag tcgccgacct cgatcagggc
    12781 gggaacctcg tacacgtctt ccttggccat gaaagccacc tccgtctgtc gagtggcgcc
    12841 ggtcggtccc ggacgccggg tgtcggtccg acgggacgat ccgttgcgct cactcggccc
    12901 gtccgcctgg cacaacgcta tggaccgggc cactcggacg cacgacacct gttcgagtga
    12961 caagcgcctg tgcgaggagg tctgcgcgag gtggtctgtg tgcccaacag tccgcccacc
    13021 accgcggacg gcgtcgtggc gaccgtccgc gcctccggcg ggagtaccgg gagtaccggg
    13081 agacgcggtc gagcggcgcg gcggcacctg cgcacgggtc ggtacagccc ccgcgcacag
    13141 gcgtacggcg cgccgtggac gtcgcacggc cgccggcgcg gccgggcggg tcagtgcgcc
    13201 gcgccgaccg gctcctccgg ttcggccgcg ccgacgaagg tccgccacag ccgggcgtac
    13261 cggccgtcga gcgcgaggag ttcgtcgtgc gtgccgtcct cggcgacccg tccgtcggcc
    13321 atgacgacga cgcggtccgc gcgggcggcg gtggtcagcc ggtgggcgac gacgagcgtc
    13381 gtgcggcgtc ccgctatgcg gtcggtggcg tggttgacct gcgcctcggt ggccaggtcc
    13441 agggcggccg tggcctcgtc gaggagcagt acgtccgggt cgacgagttc cgcgcgggcc
    13501 agcgcgatga gctggcgctg gccggcggag aggttgcggc cgcgttcggc gacctcgtgg
    13561 aggtagccgc cggtgagggt ggcgatcatc tcgtgggcgc ccaccgcccg tgccgccgcc
    13621 tccacctggg cgtcggtggc gtcggggcgg ccgtaggcga tggcgtcccg gacggtgccg
    13681 gggaagaggt acgcctcctg cgggacgacg cccagccggt gccggtaggc ggtcaggtcg
    13741 agggcgcgca ggtcctgccc gtcggcggtg acccggccgc cggtcgggtc gtagaaccgg
    13801 gccaccagct tgaccagcgt cgacttgccc gcgccggtct cgccgacgaa ggcgacggtc
    13861 tgcccggcgg ggatgcgcag gtcgatgccg gtgagggcct cctcctcgtc gccgtaccgg
    13921 aagtgcacgt cctcgaaggc gatctcgccc cgcagggacg tcaccccgcg gggccggtcg
    13981 gcggtccggg tggaggcggg ctcgcgcagg agttcctgga tgcggccgag ggagacggac
    14041 gcctgctggt agccgtcgaa gacctgggag agctgctgga ccggcgcgaa gaacaggtcg
    14101 atgtagagca ggtacgcgac cagcgcaccg gtcgtcaggg tcgcgttgtc gatccgcgtg
    14161 ccgccgacga tcagtacggc cgccgcggcg gccgacgaca gcagctgcac gaacgggaag
    14221 tagaccgaga tcagccactg gccgcggatg cgggcctgcc ggtagccgtc gctgcgctcg
    14281 gcgaaccggc gcccgccgtc gtgctcgcgc cggaaggcct gcacgatccg cagcccggcc
    14341 accgactcct ggaggtcggc gttgaccgtg gagacccgct cgcgggccag ctcgtacgcc
    14401 ttcacgctgg cccggcggaa gaagtacgtg gcgatgatca gcggcggcag cgtcgcgaag
    14461 acgacgaacg ccagctgcac gtcgatcacc agcagcgcga cgaggatgcc gaagaacgtg
    14521 acaaccgaga cgaaggcggt gaccaggccg gtctgcagga acgtggacag cgcgtccacg
    14581 tccgtcgtca tccgggtcat gatccggccg gtcagctcgc gctcgtagta gtcgagtccg
    14641 agccgctgga gctgggagaa gatcttcagc cggagcgagt acaggatccg ttcgcccgtg
    14701 cggccggtca tccggatctc gccggtctgc gccgtccact gggcgagcac ggcgagcagc
    14761 ccgagcagcg aggcagccca gaccgcgccg agggcgagct gtgtgacgcc ctcgtcgatg
    14821 ccgtgccgga tcagtacggg cagcagcagg cccgtgcccg cgtccacggc gacgagggcg
    14881 aggctgatca gcaggggggt gcggaagccg gccagcaggc ggcgcaggcc gtaggactcc
    14941 tccggccgga ccgccctggc ctcgtcgacg tccggggtgc cgtccgccgg gggcagcgcg
    15001 tccacccggg cgaggagttc cggggtggcc ggggtgcccg cgagggcggc gtccttcggg
    15061 gtccggtcgc cggtccacag ccggggcgtg accccgcgct cggcgtcgaa ctcggcgtcc
    15121 agctcgtcgc gtacggaggt gtcctccagc ttttcggcgg ggcgggtgtg cccgggcgag
    15181 acgccgccga gttcgtcggg gtcggtgagc aggcgccggt agagggcgga gcgttcctgc
    15241 agctcctcgt gggtgccgag gtcggcgagg cggccgcggt cgaggacggc gatgcggtcg
    15301 gcgaggccga gggtggagcg gcggtgcgcg atgaggagcg tggtgcggtc ccgcatgacc
    15361 tgcttcagcg cctcgtggat ctcgtgctcg acgcgggcgt ccacggcgga ggtggcgtcg
    15421 tcgaggacca gcaggcgggg gtcggtgagg atcgcccggg cgagcgcgac gcgctggcgc
    15481 tggccgccgg agagggtcag tccgtgttcg ccgacggtcg tgtcgtaccc gtcgggcagg
    15541 tcgccgatga acccgtgggc ctgcgccgcc cgtgccgcgg cctcgacctc ctcgtcggtg
    15601 gcatcggggc ggccgtacgc gatgttggcg cgcacggtgt cggagaagag gaaggagtcc
    15661 tcgggcacca gcccgacggc ggcccgcagc gagtccaggg tcagctcgcg cacgtcgtgc
    15721 ccgccgacga ggacggcgcc gcgccgcacg tcgtagaagc gcggcaggag cagcgagacc
    15781 gtggacttgc cggaaccgga ggagccgacg acggcgagcg tctcgccggc gcggatctcg
    15841 aaggagagcc cgtcgaggac cgggcggccg tcctcgccgt ccgtgtcgta gccgaaggcg
    15901 acgtcgtcga actcgacggt cgcgggggcg tcggccggca gcaccttcgt gccgtccttg
    15961 atcgcgggct cggtgtcgat cagctccagg acccgctcgg tgccggcacg ggcctgctgg
    16021 ccgacggtga ggaccatggc gagcatgcgg accgggccga cgagctgggc gaggtaggtg
    16081 gagaaggcga cgaaggtgcc gagcgtgatg tgcccgcgca ccgccagcca gccgccgagg
    16141 gccagcatgg cgacctgccc gagcgcgggg acggcctgga gggccggggt gtaggtggcg
    16201 ttcagcctga tcgtccgcag ccgtccggcg aagagcctgc gcccgacctc ccgcagcttc
    16261 ccggtctcct gctcctcctg cccgaagccc ttcacgacgc gtacgccgcc gaccgagccg
    16321 tcgaccaccc cggcgacggc cgcggcctgc gcctgcgcgt accaggtggc ggggtgcagg
    16381 cgggtccggc tgcgacgggc gatgaaccag agcgccgggg cgacggccag cgcgatcagg
    16441 gtgagcggcg gggacagcca ggccatgatg cccagggaga tcaggaagag cagcacgttc
    16501 ccgatggtca tcgggagcat gaagagcagg ctctggatca gctggaggtc gctggtcgcc
    16561 cgcccgacga cctgtcccgt ggacagctcg tcctgccgtc gcccgtccag ccgcatgatc
    16621 gtcgcgtaca tgtcggtgcg caggtcgtgc tggacgtcga gggcgaggcg gccgccgtag
    16681 tagcggcgga tgtacgccag gacgtagacg acggccgcgg cgccgacgag gagcccggcc
    16741 cagacggcca tggaccgggc cttcgcaccg atcacgtcgt cgatgatcac cttggtgatc
    16801 agggggacga gggccatgac cgccatgccg cccagcgagg cgccgagggc cagtacgacg
    16861 tccttgggat ggcgccgggc gtaggccgcc agtcgtcgtg cccatccccg ttgcgcgtcc
    16921 acgcggtgcc ctccggtcgg tcgtcctgct cacctgatct accggaaggc tccaacacgg
    16981 gcgaggtggg atttcatccc gctgtaacaa ttcggggcac cgctcacggg cggcagtcgc
    17041 tcacgtgcgc acgcggagcc tgaggaagcg ggtcgtctgt acgtcgttct ggttgtcgtc
    17101 gctgacgatc aggacgtccg tacggtcccg ggagcggccg gtgacggcca tgccctcgaa
    17161 gttgtcgagg agcgggttgg gctggggctg cccggcggtg gcgccgagcg aggggcagtc
    17221 ggcgaggtcg gcgaggagcc gcttggggag cggggtgccg cgcggggtgc cgcggccggg
    17281 gcggtcggcc aggtggaggc ggatcgtgtt gccgacgccg gaggtgaagc cccgctccag
    17341 gacgagcagg cgcccgtcgg gcagggcggt gacctcggag acgccgagcc cggcgtccgt
    17401 ccggtacgtg taccggtccc cgagccggaa gccgccgtcc cgcgtccgct gccaggtctg
    17461 gaggcggacc aggtcggcgg ggtcgccgtc gagctggtac tccatcgagg cgagcagcgt
    17521 gcgaccgccg gggaggaggg tcagcccctc gaagctcccg ttctcctgcg cgcgtccctc
    17581 gggagcggtg cggaggtcgt ccggcacggg gaggcggccg aggatctcgc cggtgcggga
    17641 gtagcggcgg acggacggct cggtctcgga ggagacgagg taggtgccgt cccggtcgac
    17701 gaccagcccc tcggagtcga gcgcggcgcc ctcctcgtcg gcgagcggga tcacgccccg
    17761 cggctgcagg gtccgcgcgt ccagccggaa gagggacgag cggtcggcga gcgcggccac
    17821 ggtgccgcgc cggtcggggg cgagggcgga gaggttgccg acgtaggtgc cgtcgtacgt
    17881 cgtcttgtcg aggacgtcgg agaagccggc gagggagacg gagcgcgagc aggcgttccg
    17941 ctgggagttc cccggagagc ttccctgggc ggcggccggt ccggcggcgg tgaggcagcc
    18001 ggccgcggcg agacctgcgg tgagggcggc gagggcggta cggaggattc tcgggcgcat
    18061 ggccgtcacc ctagggcgcg ggggtggccg ggagttggcc gcttctcgaa ggacggggtt
    18121 ccgggcgccc cggcgtttcc ggcgccccgg agtctccggc atccctgggg tttccggcac
    18181 tccgcgagtc cgcgccccgg gcacggccgg ccgccggacg ggccgcccgg gagttggggc
    18241 ctgccgccgg acggcgcctc agccctccac gatcgcctgg agagcggggc cgtagtagcg
    18301 gaccacggtg tcggtgtcgg ccgcggccag gggttcgagg accgcgatgt accgcatcat
    18361 cgcgagtccg atgagctggg tggcgatcag gttcgaccgc aggaccgcgt cctcgcccgt
    18421 gacgacgttg ccgagcgcgt ccgccaggat cgtggtcgcg gtctcgcgca gccgggcggc
    18481 ggccacgcgg tgcacggacg ccgaacgcac catggtcatg agcgcgggcc gcgtcgagag
    18541 gtcgtcccac agcgcgaggt gcgcgcgcac catgcgctcc ccgaccccct cgcgtccgcc
    18601 ttccgcggcg gcggcgaggg cctgcggcat cttcagcggc acctccagcg cctgcaggaa
    18661 gaggttctcc ttcgtgccgt agaagtggtg gaccagcgac tggtccacct ccgcggcctc
    18721 cgcgatgcgg cgcatgctcg tcgcgtcgaa cccgcgctcg gcgaaacacg cccgggccgc
    18781 gtccaggatc gcctcgcggg tgcgggtctc cccgggccgc cggcccccgg cgtgcttgcc
    18841 cgccggaacc gccccggcca ccgccccggc ccgctcgcgg tcggcaccgc ccgcctcacg
    18901 cacatcgtcg acgctcttca tgcccccatg atgcccgccg cccgtcggtc cgcattaagt
    18961 catcacatga tgaactcagc gcatgatgag tttatagtga gacagatcct ccccgcctcc
    19021 ttctccctct ctccctctct cccgggacgg ttgccatgtc cacgaacctc accacctccg
    19081 ccgcatcgga gccggacggc ggcgcctcct ccgccccgcc gccgggcggc cggaagcccg
    19141 tcatacggct cgccgccatc gtggtcggcc tgaccgcggc gatcaccgtg atgctgtgcg
    19201 ccttcgccct gccgtccgtc aacggcggcc cccaccacgc cccgctgggc gtcaccggcc
    19261 ccgccgcgca gagcgtgcag gcgaagctgg acggcgacgc gtgggacgtc acggtgtacg
    19321 acgatgccga ggccctcacc gacgccatcg aggaccgtga cgccgtgggc ggcatcgccc
    19381 tgggctccga cggcgtcacc gtcctcaccg cgaccgcggg cggtcagctg atctccaccg
    19441 cgatcggcgg gctcggcgag acgctcgccg agcagcagca cgtctccgcc accgtccggg
    19501 acctcgtacc gttcccggcg gacgacccgc ggggcaccgg actcaccggc gccgcgctcc
    19561 cgatggtctt cggcggcatg ctccccgcga tcgtcctgct ccaggtcttc cccggccacg
    19621 ccaggctgcg gacccggctc gccggagtgg tggccttcgc gctcgcggcg ggagtcgccg
    19681 tcagcgccgt tctcacgtac gggaccggca cgctcgacgg caacttctgg atcacctcgc
    19741 tcggactcgc cctgggcatg gccgcactcg ccgttccctt cctggggctc gagtcgctgt
    19801 tcggcttcgc cggattcggc gccggggccg cggtgacgat gttcctcggc aacccgctct
    19861 ccggcctccc caccggcccg tactggctgc cggacggctg gtccaccttc gggcaactcc
    19921 tgccgcccgg cgcctcgggc agcctgctgc gcgccaacgc ctacttcgac ggcaccggcg
    19981 cgggcggccc ggcgctcgtc ctgaccgcct gggccgccgt cggcctggtc ctcatgctcg
    20041 ccgccgaccg ccgcaaccgc aggaagggcg ccgcccggcc ggcggtgtga ccgcacggcc
    20101 cgacctgacg cggggcgggc gctccccgcc ggagattcac agcctgtccc caggcggacc
    20161 acagcccgcg cccaacggcc gtggagacgg tggcccggtg acatcttctg ccaccgctcc
    20221 cccgcacgcg gccaccgagc cgcccgcccc ctcccccgcc gacgccccgc cccggtggtc
    20281 gcggcccgcg ctgctcgcga tcctcgtcct ggcggccggg ctgtacgcct ggaacctgtc
    20341 cgggtccgga ctgaacagct tctacagtgc cgccgtgctc agcggcaccg agagctggaa
    20401 ggcgtggttc ttcggctcgt tggacgcggg gaacttcctc accgtcgaca agccgcccct
    20461 cgccctgatg gtcatgggcc tgtcctgccg cctcttcggc tacggaacct ggcagatgat
    20521 gctgccgctg atcggggccg cgctggcgac gatctggatc ctgcacgcgt ccgtgcggcg
    20581 ggtgtggggc cacggcgcgg cggcggtcgc cgcgctggtg ctggcgctga ccccgatcac
    20641 ggtcgccatc aaccgggaca acaacccgga caccctcctg gtgttcctga tggtggccgg
    20701 ggcggcgctc ggcctgcggg cgacccgcga cgggcggctg ctgccgctgc tgggctcggc
    20761 ggtctgcttc gggctggcct tcaacacgaa gatgctccag ggctggatcg cgctgccggc
    20821 ggtcttcctc gtgtacgtgt acgcgagcga cctcggctgg gcgaagcgcg tccggaacct
    20881 ggcgctcgcc gcggtcgccc tggccgtcgc cagcttctgg tgggcggctg ccgtgtccct
    20941 ggtgccggcc tccgagcggc cgtacatcgg cggttcgacg gacggcacgg cgtgggacct
    21001 gatcctgggc tacaacgggc tcggccggat cctcggcggc gacggcaaca tgggcggagg
    21061 cggcggagca ggtggcggcg ggggcttctc gggcaccgcg ggcatcgggc ggatgttcaa
    21121 cgacgtcctc ggcggccaga tctcctggct gctccccttc gcgggcatcg cgctcgccgg
    21181 cggcctggtg ctgtgcggcc gggcgccccg taccgacctc acccgggccg cgctcgtgct
    21241 gtggggcggc tggacggtcc tgcactacct gacgttcagc atggccgagg gcaccatgca
    21301 tccgtactac acgaccgcgc tcgcaccggg catcgccgcg ctctgcgggg gcggcggcgt
    21361 gatgctgctg cgtgccttcc gggccgaccg gcgctgggtg tgggtcctgc cgctcgccct
    21421 cggggtcacc ggcctctggg cggtcgtgct gctgcgccgt gcctccggct ggaacacctg
    21481 gctgtggccg tcggtcgcgg tggtcatggc gctggcggtc gccggactgc tggtcttccg
    21541 ctcggggcgc cgggtgcggc tgctggcggt gtccgtggcg gcggccgtcg tcgcgggcat
    21601 cgcgggtccg gcggcgtacg cctggtcggt gccgtccggt tccgggggcg gcatgggcgg
    21661 gaccaacccg accgcggggc cttcgacggg cggcggcatg ggcggtccgg gtttcggagg
    21721 cggcggccgg ggcggggccc cgggcggcgg cgagggcgcg cccggcggcg ggggccaggg
    21781 cggacagccg cagggcggcg gccggggcgg tccgggaggc gggagcttcc ccggcggtgg
    21841 atcggccccg gacggcgggc ccgccccggg cggcggcgac ggccgggcct ccgagggtgc
    21901 gggcgactcg accggcacgg ccccggaggg cagcggcgcg ggcacggacg ggcagcaggg
    21961 cagcaccgga ggctccggcg gagacggtgg cggcggcggc atgggcggtc cgggcggcgg
    22021 aggcggcggt ggcatgggcg gtgccagcac cgaactggtc gcctacctga agaagcacca
    22081 ggacggtgcc aagtggctgc tcgccgtgtc gagttcgcag agcgccgcgc agctcatcct
    22141 cagcagcggc gaaccggtca tctccatgtg gggctggtcc ggcagtgaca acgcgatgac
    22201 cctcgccagg ctcaaggagc tggtgcagaa gggcgagttg cactacgtcc aggtcggcgg
    22261 gggcatgggc ggcggccccg gcggcggtga cggactcagc tcccaggtga ccgagtggat
    22321 ccaggagcac ggcacggccg tggacgagag cgagtacggc ggcacctcca ccgacgcgtc
    22381 cgactccgag tcgcagtccg attcgcagtc cggttcgcag tccggctcac agggctcgca
    22441 gtcggacagc gcgtccggtc tctaccggct ggaccccgcg gacgtggact gaccaccgca
    22501 ccacccaccg gaaggatcat ca
//
