LOCUS       NZ_CP036534            21059 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. VN1 chromosome, complete genome.
ACCESSION   NZ_CP036534
VERSION     NZ_CP036534.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. VN1
  ORGANISM  Streptomyces sp. VN1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8341703)
  AUTHORS   Nguyen,H.T., Pokhrel,A.R., Nguyen,C.T., Pham,V.T.T., Dhakal,D.,
            Lim,H.N., Jung,H.J., Kim,T.S., Yamaguchi,T. and Sohng,J.K.
  TITLE     Streptomyces sp. VN1, a producer of diverse metabolites including
            non-natural furan-type anticancer compound
  JOURNAL   Sci Rep 10 (1), 1756 (2020)
   PUBMED   32019976
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8341703)
  AUTHORS   Pokhrel,A.R., Nguyen,H.T., Dhakal,D., Nguyen,C.T., Pham,V.T.T. and
            Sohng,J.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2019) Department of BT-Convergent Pharmaceutical
            Engineering, Institute of Biomolecule Reconstruction, Sunmoon-Ro221,
            Asan, Chungnam 333-708, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: APR-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: HGAP3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_011650445.1-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 03:53:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,284
            CDSs (total)                      :: 7,197
            Genes (coding)                    :: 7,083
            CDSs (with protein)               :: 7,083
            Genes (RNA)                       :: 87
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 44 of 114
            Pseudo Genes (incomplete)         :: 82 of 114
            Pseudo Genes (internal stop)      :: 3 of 114
            Pseudo Genes (multiple problems)  :: 15 of 114
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:32:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 237496
            Orig. end                         :: 258555
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP036534.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jae Kyung Sohng.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    463..480
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.29"
                     /tool="antismash"
     misc_feature    complement(566..581)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.01"
                     /tool="antismash"
     gene            complement(667..1686)
                     /locus_tag="EZV63_RS00700"
                     /old_locus_tag="EZV63_00735"
     CDS             complement(667..1686)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446243.1"
                     /locus_tag="EZV63_RS00700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00735"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_031032192.1"
                     /transl_table=11
                     /translation="MRVSLKDVAAHAGVSVKTVSNVVNDYPYVTAAMRERVQRSIDELG
                     YRPNLTARHLRKGRTGIIALALPELGNPYFAELAAAVIDAAAAHDYTVLLDHTGGRREQ
                     EILVSQGFRARVIDGLILSPIELETEDLRDRTGDVPMVLLGERDYDLPYDHIAIDNVAA
                     ARAAVRHLIGLGRREVAFIGDRRGRSEPAQLRVRGWREELAEAGLPADDGLVADTDGWG
                     HADGAAAMARILEAGRRPDAVFAYNDLVAIGAMRVLHARGLRVPEDIAVVGFDDVVEGR
                     FGAVTLTSVSPDKEAIGRLAVESVLARLGGKPAEPRRFRADHRLAERESTLGRGAANA"
     misc_feature    complement(1767..1783)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.52"
                     /tool="antismash"
     misc_feature    1776..1791
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    1816..1827
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            2100..3719
                     /locus_tag="EZV63_RS00705"
                     /old_locus_tag="EZV63_00740"
     CDS             2100..3719
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012363.4"
                     /locus_tag="EZV63_RS00705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00740"
                     /product="carboxylesterase family protein"
                     /protein_id="WP_107448182.1"
                     /transl_table=11
                     /translation="MLLGTVLAAAPVNAAPADGGHRTTVVRTDLGRVEGLDQGRSSGTY
                     SWLGIPYAQPPVGPLRWRAPVTHRPWQGLRDATAYGDGCAQQGRLFSPAPSGPHYGLDV
                     RDGLDEPVGAEDCLTLNVFRPSTAKKDLPVVVFVHGGSNVVGYSADPMYDGRALARGAD
                     AVVVTVNYRLGVFGWLDLPGLKTGDPAGDSGNFGTLDQIEALRFVRRNASVFGGDASNV
                     TVMGESAGAVDVWALMTSPLSRGLMDKAVPLSGGLKFSAPAQARTYAEAFLDEAVGPGG
                     SREEAVRRLRELPADDVVRAQVRRGAAVGDPPAVLADGVVLPADHHDVVRTGRLREMPV
                     LAGNTFEEGKLFGSLVDAYRPTDRERFTKQYFFDPDKPSPFGVRDFIADRYLPADGPGG
                     WNEAAGRLTDSIFTGIVHDSMDSMREAGNEHLYYYQFGWDREPAPFDTVYGAAHAMDLP
                     FVFGTFDEGLFTFAFSRRNEPGRLQLSKLMTESIRAFVRTGRPQHRGLGAHWGRWPHSM
                     VFDATDRSADARPGSADGRSRG"
     gene            complement(3838..4095)
                     /locus_tag="EZV63_RS00710"
                     /old_locus_tag="EZV63_00745"
     CDS             complement(3838..4095)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948466.1"
                     /locus_tag="EZV63_RS00710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00745"
                     /product="hypothetical protein"
                     /protein_id="WP_037771195.1"
                     /transl_table=11
                     /translation="MTKSRKTAEPAPAPEPAPEPVPCPDVAARAAAFLDGQQITTTQCG
                     LCGTEIAGVNGRYSCGVCGWTNPWWEGTSTLPGATDYDQG"
     gene            complement(4155..5138)
                     /locus_tag="EZV63_RS00715"
                     /old_locus_tag="EZV63_00750"
     CDS             complement(4155..5138)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057132.1"
                     /locus_tag="EZV63_RS00715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00750"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_166623426.1"
                     /transl_table=11
                     /translation="MTHQQRPIGSGFTPASTADEVLAGTDLTGRNIVVTGGHAGIGREA
                     TRALTARGASVTVGSRNPERAREALVGLDGVQIGRLDLADPASVDAFAVRWNVSGRPLH
                     VLVNCAGVAAPQEREVDSRGYELQFAVNHLGHFQLTRALLPALRAAHGARVVNVTSGAH
                     RFSTIRWNDPHFDSGDYTPQLAYAQSKNANVLFTVELDRRWAGDGIRGYAVHPGVVVGT
                     ALNSAAGTDGLRAAGLIDEDGRPVIDPVVGKKTVQQGAATVVFGAASPLLADIGGVYLK
                     DSDVAPLDDEHRPVTADSLPADAASHSIDPQNAARLWELSERLLGA"
     gene            complement(5283..6284)
                     /locus_tag="EZV63_RS00720"
                     /old_locus_tag="EZV63_00755"
     CDS             complement(5283..6284)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140210.1"
                     /locus_tag="EZV63_RS00720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00755"
                     /product="chlorophyllase"
                     /protein_id="WP_228773691.1"
                     /transl_table=11
                     /translation="MPASASASASASASAPAPGTVREATPVLSYAPVTLRVPGRPADLT
                     LRVTAPETGTDLPLILLSHGHGGSLSLSSEDGYAPVAQRWAAAGFVVIQPTHLSSRRLG
                     HLWETTAGAPLFWRSRAEDMIHVLDHLDEIERVVPLLAGRLDREAVAVAGHSLGGSTAE
                     LLLGAGVTDPDSGERVSLLEPRIKQGLLLAAPGRGGDTLNGPMADQVPVFRTVDFTTMT
                     GSALVVAGDQDDSRHFTDMGPAWHYDPYHLAPGAKTLLTVFGAGHLLGGIQGYDAAESA
                     QLSDENPGHVAAIARLSAAYLHSRFGRGDDAWKQARQELTTGPEAVGRVESK"
     gene            6545..7090
                     /locus_tag="EZV63_RS00725"
                     /old_locus_tag="EZV63_00760"
     CDS             6545..7090
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018570589.1"
                     /locus_tag="EZV63_RS00725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00760"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_107405235.1"
                     /transl_table=11
                     /translation="MRADARRNQEKLLAAAAEVFVGSGVDAPIRQIAARAGVGMGTIYR
                     HFPTRSDLVVAVFRHQIEECAEAGPRLLSEAGSPFAALQRWIDLFVDLLVTKHGLAQAL
                     QSDSSRFAPLHAYFLDRLQPVATRLLDAAAEAGEIRPGIHPYELLRGIGNLCIGHDDDP
                     RYDPRRLIALLLQGLRRP"
     gene            <7299..7781
                     /locus_tag="EZV63_RS00730"
                     /old_locus_tag="EZV63_00765"
                     /pseudo=""
     CDS             <7299..7781
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003956973.1"
                     /locus_tag="EZV63_RS00730"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00765"
                     /product="peptidase C39 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="CEPVGLGVAVRRRWPSSPVEVLLDTDRPVLLDHCSDGEREWRAVV
                     QRASRTDAGRLGVPIRSRRLSLDGLRGAVGRGEHVLLLVSPAAMQGFDVPHWVLCHAVV
                     PGAVVPEDPWCNTGAGDTWADTHLLPVADASLDAMSLLTDHPFRGAVRIGRPARRD"
     gene            complement(7925..8224)
                     /locus_tag="EZV63_RS00735"
                     /old_locus_tag="EZV63_00770"
     CDS             complement(7925..8224)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972498.1"
                     /locus_tag="EZV63_RS00735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00770"
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="WP_037771204.1"
                     /transl_table=11
                     /translation="MTYGCLASMQTRPGFREEVASILLSAAEGLREAGCDIYVVGLADE
                     DDTTIRVTEVWKTKEHHDASLELPGAKEAIGRAMPLLTGEFTKQELSVAGGLGL"
     gene            8539..9981
                     /locus_tag="EZV63_RS00740"
                     /old_locus_tag="EZV63_00775"
     CDS             8539..9981
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576907.1"
                     /locus_tag="EZV63_RS00740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00775"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_166623427.1"
                     /transl_table=11
                     /translation="MSAPDSVTGPVTDESGPAAPAENPLTSLSTHAARQLATTHKSEPQ
                     MRGISSRWLIRRLPWVDVGGGTYRVNRRLHLGVGRGRVQFEQNGADDVRVIPRTLAELP
                     ALRGYADHDVLEELAGRFSVHEVRAGQVLHEAGRPVTEIFLIVHGRLTRYTAGRYGEEE
                     VLGVVTDGDHVGDEAIGRSDPLWQTSVRAETAGVVLALARDDLRELTGRAPSLAAHLAA
                     HTERQRLPVNRRGEADVPVRSGHSGEPTLPGGFVDYELTPREYELSLTQTVLRVHTRVA
                     DLFSDPMDQTRQQLRLTIQEIRERQEWELVNNRDFGLLHNVDHGQRISTSTGPPTPDDM
                     DELLSMRRATRLFLAHPKAIAAFFRQCNKRGLVPGSATVNRHHVPAWRGVPIFPCGKIP
                     VSGSHTTSIVAMRTGESDQGVVGLYQTGIPEEYEPGLNVRWMGVNSSAVVNYLVTAYYS
                     LAILVPDAAGVLENVQLGRVAD"
     misc_feature    complement(9996..10010)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.8"
                     /tool="antismash"
     gene            10001..11059
                     /locus_tag="EZV63_RS00745"
                     /old_locus_tag="EZV63_00780"
     CDS             10001..11059
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018093087.1"
                     /locus_tag="EZV63_RS00745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00780"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_037771305.1"
                     /sec_met_domain="T1TS (E-value: 9.4e-55, bitscore: 185.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTDNRTPAFSLPGPPSPARSLRARGDTAVPGLRYRPVAPADPE
                     KAAEIDRRLEAWARALDLFPPEWSGDFAQFRFGRAVALQHPEAADMERLTVAGKLLLAE
                     NIVDSCYCEEDEGRGGARLGLGGRLIMAQSALDPLHSTPEAEEGWRVGVQADGPLRSYH
                     WALKDYSAVATPSQTGRLVHDLARLHMGYLAEAAWAQTRHLPRVWEYLVMRQFNNFRPC
                     LSIVDAVDGYELPEAVYARPETQRITALACNATTIVNDLYSFTKELASDPEHLNLPQVV
                     AANDQCGLKTAYLRSVDIHNEIMEAFETESALLSETSPLVERYARGLADWVSGNHEWHA
                     SNTERYSLPDYW"
     gene            11125..12000
                     /locus_tag="EZV63_RS00750"
                     /old_locus_tag="EZV63_00785"
     CDS             11125..12000
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117983.1"
                     /locus_tag="EZV63_RS00750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00785"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_194962951.1"
                     /transl_table=11
                     /translation="MTTAHTGTTPVPVPTQSTYQNRVAEYWNAEENPVNLELGALDDLY
                     HHHYGIGDADRSVLDDPDPDQRRERITHELHRLEHSQAEFLASRLGNVSPTDRVFDAGC
                     GRGGGSIVAHLRYGCHTDGVTISRKQADFANEQARKRGVDGKVRYHHRNMLDTGLDTGA
                     YAASWNNESTMYVELDLLFAEHSRLLRRGGRYVVITGCYNDTYSQASREVSLINAHYIC
                     DIHPRSAYFKALARNRLVPVHVQDLTAATIPYWELRRNAEHLVTGIEDTFLTAYRNGSF
                     QYLMIVADRV"
     gene            12176..13147
                     /locus_tag="EZV63_RS00755"
                     /old_locus_tag="EZV63_00790"
     CDS             12176..13147
                     /NRPS_PKS="Domain: PKS_KR (21-159). E-value: 8e-12. Score:
                     37.4. Matches aSDomain:
                     nrpspksdomains_EZV63_RS00755_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949815.1"
                     /locus_tag="EZV63_RS00755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00790"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_166623429.1"
                     /transl_table=11
                     /translation="MPSTSPTPPWNVHRLPRADGRVFLITGGNAGIGYFAAEQLSATGA
                     TVVLGSRDPGKARAAGDSIRARVAGARVRAVRLDLADLSSLRTAVESLGVAHLDAVVHN
                     AGVALDDPPRTETVHGHELMFGTNHLGHFALTHWLMPLLSAAPAARVVTMGSFAAKSER
                     LDLDDLQSRADYRPKRTYGRSKLAQMYFGVELDRRLRAAGSTVRSVVVHPGGALDSLTP
                     SRPPVQVRNTGARLRAAPAALLVQGKDAGAWPAVRAVLDPAVDGGQLWGPRVFGLRGLP
                     RREPLWPQLADSGVAARLWDASCDLTGTAPGPDRREAPPHGA"
     CDS_motif       12239..12331
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EZV63_RS00755_0001"
                     /evalue="1.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="EZV63_RS00755"
                     /protein_end="52"
                     /protein_start="21"
                     /score="14.4"
                     /tool="antismash"
                     /translation="VFLITGGNAGIGYFAAEQLSATGATVVLGSR"
     aSDomain        12239..12652
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EZV63_RS00755_PKS_KR.1"
                     /evalue="8.00E-12"
                     /label="EZV63_RS00755_PKS_KR.1"
                     /locus_tag="EZV63_RS00755"
                     /protein_end="159"
                     /protein_start="21"
                     /score="37.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VFLITGGNAGIGYFAAEQLSATGATVVLGSRDPGKARAAGDSIRA
                     RVAGARVRAVRLDLADLSSLRTAVESLGVAHLDAVVHNAGVALDDPPRTETVHGHELMF
                     GTNHLGHFALTHWLMPLLSAAPAARVVTMGSFAA"
     gene            complement(13182..13553)
                     /locus_tag="EZV63_RS00760"
                     /old_locus_tag="EZV63_00795"
     CDS             complement(13182..13553)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575784.1"
                     /locus_tag="EZV63_RS00760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00795"
                     /product="VOC family protein"
                     /protein_id="WP_031032215.1"
                     /transl_table=11
                     /translation="MTATVEGPDFIALQVTDVPAAAAFFEEHLGLRRAPVSPPGAVVFG
                     TAPIPFAVREPLPGTDLSADAVPGLGVALWLRTDDAHQLHAQLVAAGVDVAGPVQDSPF
                     GPTFAFTGPEGYRLTVHGG"
     gene            13636..14097
                     /locus_tag="EZV63_RS00765"
                     /old_locus_tag="EZV63_00800"
     CDS             13636..14097
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151172.1"
                     /locus_tag="EZV63_RS00765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00800"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_031032218.1"
                     /transl_table=11
                     /translation="MTERTPVPPPHPAQDVTEHVGYRLKRTAAALRGAMDRALREHGLT
                     VPQYSCLELLDERPGLSNADLARGTFVTRQSANVVLRGLGDAGLITRPATADHGRALPA
                     HLTPAGRERLHAARGAVYAVEARMITGVPADRLPALLADLDAMTEALGD"
     misc_feature    14183..14196
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            14203..14868
                     /locus_tag="EZV63_RS00770"
                     /old_locus_tag="EZV63_00805"
     CDS             14203..14868
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828617.1"
                     /locus_tag="EZV63_RS00770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00805"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_070387226.1"
                     /transl_table=11
                     /translation="MTDPATTTEHHREGGVWARVHTERAALAADLAGLTDEEWATPSLC
                     AGLTVREVLAHLTAGASLNTVKWLAGVVRCRFDFDKQVAVRLAEHLGTTPGETLERFRR
                     VVSSTTKPPLPVVAMLGETIVHGEDIRRSLGIRRAQPVEAVTEVAEYYRGSDLVVEAKG
                     RIGGLRLVADDGPFTTGSGALVSGPTLSLVMAMTGRAAHCDDLAGDGAEILRGRCGPA"
     gene            complement(14939..15601)
                     /locus_tag="EZV63_RS00775"
                     /old_locus_tag="EZV63_00810"
     CDS             complement(14939..15601)
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446254.1"
                     /locus_tag="EZV63_RS00775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00810"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_166623430.1"
                     /transl_table=11
                     /translation="MRLLLIRHGQTPSNLKHLLDTAEPGPGLTALGEEQAAALPGALAS
                     ERIDALYASTLVRTRETAAPLASATGLDVRVRPGIRELIAGDLEMRGDDEAARTYLRTA
                     FAWSAGDVGLRMPGGEDGVEALGRYDAVVAEAYESGAGTVAMVSHGAAIRMWVAARADN
                     VDVDYAARHALANTGVVILTGSPEQGWHVLLWEGGSVGPLPHTPDPDDPAGAAVPAE"
     gene            complement(15710..16987)
                     /gene="manD"
                     /locus_tag="EZV63_RS00780"
                     /old_locus_tag="EZV63_00815"
     CDS             complement(15710..16987)
                     /EC_number="4.2.1.8"
                     /GO_function="GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="manD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058550.1"
                     /locus_tag="EZV63_RS00780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00815"
                     /product="D-mannonate dehydratase ManD"
                     /protein_id="WP_166625882.1"
                     /transl_table=11
                     /translation="MAAVSDHPRTDPVKITAADVVVTSPGRNFVTLRITTEDGLTGLGD
                     ATLNGRELAVEAYLREHVAPLLPGRDAHAVEDTWQYLYRGAYWRRGPVTMAAVAAVDTA
                     LWDIKGKAAGLPVYQLLGGACRTGALAYGHASGRDVPELLDSVREHLADGFRAVRIQSG
                     IPGLDSVYGVAASAAGDGERYDYEPARRTRAAHPRPTEETWDTRAYLRHMPTVFEAVRN
                     TFGPELPLLHDGHHRMTPIQAARLGKDLEPYDLFWLEDATPGEDQGALRLIREHTTTPL
                     AIGEVFNSVHDYTTLLQERLIDYVRSAVTHTGGITAVRKLLDMAAVYGIRSGMHGPTDI
                     SPVGMAAALHLDLAVHNFGIQEYMRHAPDTLEVFHTSYRFEDGLLHPGDAPGLGVELDD
                     EAAARFPYRPAYLPVNRLGDGTVHDW"
     gene            complement(17117..18640)
                     /locus_tag="EZV63_RS00785"
                     /old_locus_tag="EZV63_00820"
     CDS             complement(17117..18640)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131479.1"
                     /locus_tag="EZV63_RS00785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00820"
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_166623431.1"
                     /transl_table=11
                     /translation="MGFEATYADFSVDPPRLSNAEAGFHGGGFAGSHVALGADGAVTLD
                     FEVQDPQDVPQATLTVTALVSKLGSSLGYAPMTVRLQGETLAQDLTVPGGGDLPHDNVL
                     AVPGDLLKPGTNRLEIRSSPKAASMLWLYRVTLDPVRERGRSERARTAGAARDSVFAYR
                     TELRPAHASSAPWQSAPRLLFHLDRGEQSLPAQLGWRGEDGAEATIGFASGMADFRGCY
                     RAEDGTAYEYRGDLTDRWPFSDETEHLSAYPLHRFRTEEGWGGGWHRSHDLRLLVDDGG
                     APVEGVHWRDRRGNSGSAVLHTVHRDVEVTDVDASDEFDDGGEGADNLLAGERTKWLAW
                     DDTARLDFTLARPAAVASYTLTSANDAPDRDPRDWRLHGSRDGRNWTPLDARTGETFAG
                     RWESRQFTLRGRARAYRHYRLDILRNAGAGETQLAGVRFAEAPDGQSFTGYYQRHDEGP
                     IGYRGTPAATEPSGPSADPGLAPELEAAAASLTETSRTLAALAERLRGR"
     misc_feature    complement(18912..18921)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(18931..19665)
                     /locus_tag="EZV63_RS00790"
                     /old_locus_tag="EZV63_00825"
     CDS             complement(18931..19665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152148.1"
                     /locus_tag="EZV63_RS00790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EZV63_00825"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_166623432.1"
                     /transl_table=11
                     /translation="MHITSERRLDDGVVEREFTLDGIPGILWTPAAASAPVPLILLGPP
                     PLGLRRVYPRLVGRARHAATDGFAAATIELPGSGDRPRRPAAEQARARMRRAVEAGEPV
                     TDEIVDALILPLVDEAVPEWQACLDALLALPEIGGPVGYSGGVVSIGVRLAVVEPRIVA
                     AGLFAGSLVPRAMFEEARRVTIPLHVLLQWDDEGNDRQAALDLFDAFGSEEKSLHANMG
                     GHTGVPQYEGEAAARFFARHLK"
     misc_feature    complement(19661..19674)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.39"
                     /tool="antismash"
     misc_feature    19739..19753
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            20059..20367
                     /locus_tag="EZV63_RS00795"
                     /old_locus_tag="EZV63_00835"
     CDS             20059..20367
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EZV63_RS00795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EZV63_00835"
                     /product="hypothetical protein"
                     /protein_id="WP_037771217.1"
                     /transl_table=11
                     /translation="MNYRTNVRTERRREGSKGGPFTVSLTGQWLVVALFASAIAILSRR
                     QEGTFLWIGSVLGLAAAAGFFVQFDSVANWRRGLLCALALLLGAMFTLQVFIALFTD"
     misc_feature    complement(20062..20076)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.39"
                     /tool="antismash"
     misc_feature    20068..20081
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.59"
                     /tool="antismash"
ORIGIN
        1 ggtgagcagc ttgacgcccc gcttccgggc ctcgtccttg agggactggg tctcggcgat
       61 gcggaacggg ttcgcctcct tctccgactg ggagaagccg acggtcgcac ccttcaggtc
      121 cagcttcttc gcgccgtagg cgtcgatggt gcaggtcttg ctccccggct tcggagtgac
      181 ggccttctgc tcggcgccgg ccgcggacga ggcggactgc ttcttgtccg acgcgtcgtc
      241 ctccgacttc gcgcaggcgg tcgcggtcag ggccacagcg gtggccaggg ccacggccac
      301 ggagcgggcg aggaggtgcg gacgatgagt ggtgcgctgc atggtgaccc cgatccgggt
      361 ggcgctgaaa gggaactggg gagccgaact acgagcgaca gacgactgct tctccccctg
      421 cggcaggccg tgttcggtcc gccgcacaga ggttttacat cgttgcaaga atgctgtaaa
      481 cccctcgtgc acgacctgcg accgaacccg gacccgcctc ttgacttgcg cctgacacct
      541 cactgaaact gagtggtccg gctacgtgac aacgatgtca gtaacggtgt cggcggtcga
      601 cgtgcgaact cgaccacggc cctcgcacga gtcgccgacg tacggcccgc gcgacggcct
      661 cacgcctcag gcgttcgccg cgccgcgccc cagggtgctc tcccgctccg cgagccggtg
      721 gtcggccctg aagcggcgcg gctcggccgg cttgcccccg agccgggcca gcaccgactc
      781 caccgccagc cggccgatgg cctccttgtc cggggacacc gaagtgagcg tcaccgcgcc
      841 gaaccgcccc tcgacgacgt cgtcgaaccc gacgacggcg atgtcctcgg gcacgcgcag
      901 ccctcgcgcg tgcagcaccc gcatcgcccc gatggccacg aggtcgttgt aggcgaacac
      961 cgcgtcgggc cgccgccccg cctccaggat ccgggccatc gccgccgcgc cgtccgcgtg
     1021 cccccacccg tcggtgtcgg cgaccagccc gtcgtcggcg ggcagccccg cttcggccag
     1081 ttcctcgcgc cagccgcgca cccgcagttg ggccggttcg ctgcggccgc gccggtcgcc
     1141 gatgaacgcc acctcccggc ggccgaggcc gatcaggtgg cggaccgcgg cacgtgccgc
     1201 cgcgacgttg tcgatggcga tgtggtcgta cggcaggtcg tagtcccgtt cgccgaggag
     1261 caccatcggc acgtctcccg tgcggtcgcg caggtcctcc gtctccagct cgatgggact
     1321 gaggatgagc ccgtcgatca cccgtgcccg gaacccctgg ctgaccagga tctcctgctc
     1381 ccggcgtccg ccggtgtggt cgaggagcac ggtgtagtcg tgcgcggctg ccgcgtcgat
     1441 gacggccgcg gccagttcgg cgaagtaggg gttccccagt tcgggcaggg cgagcgcgat
     1501 gatgcccgtg cgccccttgc gcaggtggcg cgcggtcagg ttcggccggt atccgagttc
     1561 gtcgatggac cgctggacgc gctcccgcat ggccgcggtg acgtagggat agtcgttgac
     1621 cacgttggag acggtcttga cggagactcc cgcatgcgcg gcaacgtcct tgaggctgac
     1681 ccgcacgtcg aatccctccg cagcggcccc cactcggcgc ccggtgcgcg agggcctgtc
     1741 tcccgctccg gccggactcc aagcctctgg gctgaattta caacgttata cagcccgtct
     1801 ccgggcactg acaagcgaaa tgaacgcccg ctcgggggca tcctgggcag cctcacctca
     1861 tcctcacatg gtggcaccac ccgcccgtgg ccgggcacgt ccgcgaccgc cgcgccgacg
     1921 gtggttcttc ttgccaccgg accgccggca gccatggagc attcccacct cgtgacgccc
     1981 cgcaccggtc cctacagtga cggccaccac accgggttgt cccggtccgc cccggaccgg
     2041 gcagagcccc ccgctcgaag ggagtggagc cagtgaggac gacgaggcgt cttggtgccg
     2101 tgcttctcgg gacggtgctc gcggccgcgc cggtgaacgc ggcgccggcc gacggcggcc
     2161 accggaccac cgtggtgcgg accgatctgg gcagggtcga gggactcgac caggggcggt
     2221 cgagcggaac gtactcctgg ctgggcatcc cctatgcgca accgcccgtg gggccgctgc
     2281 gctggcgtgc cccggtgacg caccgcccgt ggcagggcct gcgggacgcc accgcgtacg
     2341 gggacggctg cgcccagcag ggccggctct tcagcccggc accgagcggt ccccactacg
     2401 ggctggacgt ccgggacggc ctggacgagc ccgtcggcgc cgaggactgc ctcaccctca
     2461 acgtgttccg tccctcgacg gcgaagaagg acctgccggt cgtcgtcttc gtccacggcg
     2521 gcagcaatgt ggtcgggtac tcggcggacc cgatgtacga cgggcgcgca ctggcgcgcg
     2581 gggcagacgc ggtcgtggtc acggtcaact accggctggg ggtcttcggt tggctcgacc
     2641 tgcccggtct gaagaccggc gacccggccg gcgactcggg caacttcggg acactggacc
     2701 agatcgaggc cctccgcttc gtccgtcgca acgcgtccgt cttcggcggt gacgcgtcga
     2761 acgtgaccgt gatgggcgag tccgccggtg ccgtcgacgt ctgggccctc atgacgtcgc
     2821 ccctgagcag gggcctgatg gacaaggccg tcccgctcag cggcggcctc aagttctccg
     2881 ctcccgccca ggctcgcacc tacgccgaag ccttcctcga cgaggccgtc ggccccggcg
     2941 gcagccggga ggaggccgtg cgacggctgc gggagctgcc cgcggacgac gtcgtgcggg
     3001 cccaggtgcg ccgcggtgcg gccgtcggcg atcccccggc ggtgctggcg gacggcgtcg
     3061 tgctgcccgc ggaccaccac gacgtcgtcc ggacgggccg gttgcgcgag atgcccgtgc
     3121 tggcgggcaa caccttcgag gaagggaagc tcttcgggtc actcgtcgac gcctaccgcc
     3181 ctaccgaccg cgagcgcttc accaagcagt acttcttcga tcccgacaag ccctccccct
     3241 tcggcgtccg tgacttcatc gccgaccgct acctgccggc cgacggcccc ggcgggtgga
     3301 acgaggcggc cggacggctg accgacagca tcttcaccgg gatcgtccac gactccatgg
     3361 actccatgcg ggaggccggc aacgagcacc tgtactacta ccagttcggc tgggaccggg
     3421 aaccggcacc gttcgacacg gtctacggtg ccgcgcacgc catggacctg cccttcgtct
     3481 tcggcacctt cgacgagggg ctgttcacgt tcgccttcag ccgccgcaat gaaccgggcc
     3541 gcctgcagct ctcgaagctg atgacggaga gcatccgcgc cttcgtgcgc accgggcgcc
     3601 cgcagcaccg cggcctcggc gcgcactggg gccggtggcc gcacagcatg gtcttcgacg
     3661 ccaccgaccg gagcgccgac gcgcggcccg ggtcggccga cggccggtct cgcgggtgac
     3721 ggccggtctc gcggctgacg gacgcggtgc ggagtctccc ggctcgttcc ggggccgggt
     3781 gccgaggcgc gccgggcggg gtcgggcccg gggccggggc acgccgggcg gccgccctca
     3841 tccctggtcg tagtccgtcg cgcccggcag cgtgctggtc ccctcccacc acgggttggt
     3901 ccagccgcag accccgcagg agtaccgccc gttcactccg gcgatctccg tgccgcacag
     3961 tccgcactgc gtcgtcgtga tctgctggcc gtccaggaag gcggccgccc tcgcggccac
     4021 gtccggacac ggcaccggct cgggtgccgg ttcgggtgcc ggtgccggtt cggcggtctt
     4081 gcggcttttc gtcacgcccg tgagcctacg cgcgtttcgg gtccggacgg agcccgctgc
     4141 tccagcctcc tccgtcaggc gccgagcagc cgctcgctca actcccagag gcgcgcggcg
     4201 ttctgcgggt cgatggagtg ggacgccgcg tccgccggga gactgtccgc cgtcaccggc
     4261 cggtgctcgt cgtccagcgg tgccacatcg ctgtccttca gatagacgcc cccgatgtcc
     4321 gcgaggagcg ggctcgcggc gccgaacacg acggtcgcgg cgccctgctg caccgtcttc
     4381 ttcccgacca ccgggtcgat gaccggcctg ccgtcctcgt cgatcagtcc ggcggcacgc
     4441 agcccgtccg ttccggccgc gctgttgagc gccgtaccca cgaccacgcc cggatggacc
     4501 gcgtagccgc ggatgccgtc cccggcccag cggcggtcca gttcgacggt gaagaggacg
     4561 ttggcgttct tcgactgggc gtaggccagt tgcggggtgt agtcgccgga gtcgaagtgc
     4621 ggatcgttcc agcggatggt ggagaagcgg tgggcgccgg aggtgacgtt gaccacccgg
     4681 gcgccgtgcg ccgcccgcag agcgggcagc agggcgcgcg tgagctggaa gtggccgaga
     4741 tggttgacgg cgaactgcaa ctcgtagccc cgtgagtcca cttcccgctc ctggggcgcc
     4801 gccacccccg cgcagttcac cagaacgtgc agggggcgcc cggaaacgtt ccaccggacg
     4861 gcgaacgcgt cgaccgaggc ggggtcggcg aggtcgagcc ggccgatctg cacgccgtcg
     4921 aggccgacca gagcttcccg tgcccgctcc gggttgcgtg agccgacggt caccgacgcg
     4981 ccccgcgccg tcagggctcg ggtggcttcg cggccgatgc ccgcgtgccc gccggtgacg
     5041 acgatgttcc ggccggtcag gtcggtgccg gccagtacct cgtcggccgt cgaggccggt
     5101 gtgaatccgg acccgatggg ccgctgctgg tgagtcatgt gcttgtcctc ttcttcatcg
     5161 ggtttcatcg ggttcatcgg ggtgtcgcgt tcgtcggctc gtcggggtgg cgtgccgcct
     5221 cgccttgccg ggcaccgccc ggcccgggtt gcggtccgga cagggcccgt ccgccggtcc
     5281 gcctacttcg actcgacacg tccgaccgct tcggggccgg tcgtcagctc ctgccgggcc
     5341 tgcttccagg cgtcgtcgcc acggccgaac cgggagtgca ggtaggccgc gctcagccgg
     5401 gcgatcgcgg cgacgtgacc ggggttctcg tccgacaact gcgcgctctc ggccgcgtcg
     5461 tacccctgga tgccgccgag caggtgcccc gcgccgaaga cggtgagcag ggtcttggcc
     5521 ccgggggcga ggtggtaggg gtcgtagtgc caggccggcc ccatgtccgt gaagtgccgg
     5581 gagtcgtcct ggtcaccggc cacgaccagc gcggacccgg tcatcgtggt gaagtcgacg
     5641 gtgcggaaca ccggcacctg gtcggccatc ggcccgttga gggtgtcgcc gccccggccg
     5701 ggcgcggcca gcagcaggcc ctgcttgatc cgcggttcca gaaggctcac tcgctctccc
     5761 gagtcggggt cggtgacgcc cgcacccagc aggagttcgg ccgtcgagcc gcccagggag
     5821 tgcccggcga cggccaccgc ctcgcggtcg aggcgcccgg cgagcagcgg cacgactctc
     5881 tcgatctcgt ccaggtggtc gaggacgtgg atcatgtcct cggcgcgcga acgccagaac
     5941 agcggcgcgc cggcggtggt ctcccacagg tggccgagcc gtcgggagct gaggtgcgtg
     6001 ggctggatca cgacgaatcc ggccgccgcc caccgctggg cgaccggcgc gtagccgtcc
     6061 tccgaggaca ggctgaggga tccgccgtga ccgtgggaga gcaggatgag cggcaggtcg
     6121 gtcccggtct cgggcgcggt gacccgcagt gtcaggtccg cggggcggcc cgggacccgc
     6181 agcgtcacgg gggcgtagga caacacgggg gtggcctcgc ggacggtgcc gggagcgggc
     6241 gcggatgcgg atgcagatgc ggatgcggat gcggatgcag gcatggtctg tgttcctttc
     6301 ggcgcgccga cgggggctgg ccccgcaggg gtggtggaag cgtccggtcg ccgcttccgc
     6361 agcaatcgga acatcgctcc gtttacttta cggaacatcg ttccgcttag caagcggagt
     6421 atcgttccgc attggtccgc atgccggtcc gcatgccgcg agaacctgca tgccacgaga
     6481 ccacgagaag gagagtgcgg tgcccaccac ggacgggtcg gacacgggcg ggacggcccg
     6541 gcacatgcgc gccgacgccc ggcgcaacca ggagaaactg ctggccgcgg ccgccgaggt
     6601 gttcgtcggc tcgggcgtcg acgcgccgat ccgccagatc gcggccaggg cgggcgtcgg
     6661 catgggaacc atctaccggc acttcccgac ccgctcggac ctcgtcgtgg ccgtcttccg
     6721 ccaccagatc gaggagtgcg ccgaagccgg gccgaggctc ctgtccgagg ccggatcccc
     6781 gttcgccgcg ctgcagcggt ggatcgacct cttcgtcgac cttctggtca ccaagcacgg
     6841 tctcgcccag gcactgcagt cggacagcag tcggttcgcc ccgctgcacg cctacttcct
     6901 cgaccgcctg cagcccgtcg ccacgcgcct tctcgacgcc gccgcggagg ccggcgagat
     6961 ccggccgggc atccacccct acgagctgct gcggggcatc ggcaatctct gcatcgggca
     7021 cgacgacgat ccccgctacg acccccgccg gctgatcgca ctgctgctgc agggactccg
     7081 ccgcccctga cgcactcgcc acaggcgccc cgacccggcc ggcccagggg cagtcggtgc
     7141 aggtacggcg gctcaacccg cgtcaccccc tcgaccgcac ggcggagaga ggggtggcgg
     7201 tccgctgttc cgccggaagc gctgcccggc atcccccgcc ggagcacacc gtcgcgccga
     7261 aggcggacgg gttcggtccg ctgccggggc cgcgcccgtg cgagcccgtc ggactgggcg
     7321 tcgcggtacg ccgcaggtgg ccgtcgtcgc cggtggaggt gctgctcgac acggaccggc
     7381 ccgttctgct cgaccactgc tccgacggcg agcgggagtg gcgggcggtc gtccagcggg
     7441 cgtcccggac ggacgccgga cggctgggtg tgccgatccg ctcccggcgg ctgtcgctgg
     7501 acggcttgcg cggtgcggtc ggccggggcg agcacgttct gctgctggtc tcgccggccg
     7561 cgatgcaggg gttcgatgta ccgcactggg tgctctgcca cgccgtcgtg ccgggggccg
     7621 tggtgccgga ggacccgtgg tgcaacacgg gggccgggga cacctgggcc gacacccatc
     7681 tgctgcccgt cgccgacgcg tcgctcgacg cgatgtccct gctgacggat cacccgttcc
     7741 gcggcgccgt ccgcatcggc cgcccggcgc gccgggactg aacccgcacg gggactcgcc
     7801 gcggcttccc ggccttcccc gcgctcctcg ccctccccgc cccgactccc ctccgcttcc
     7861 gcgtgctcga ccggtgcgcg caagcggggg gtcgattgca cgccccggtg gcgtcgaggg
     7921 atcgtcagag accgaggccg cccgcgaccg agagctcctg cttggtgaac tcccccgtca
     7981 gcaggggcat ggccctgccg atggcctcct tcgcccccgg cagttccagc gacgcgtcgt
     8041 ggtgctcctt ggtcttccag acctccgtca cccggatcgt cgtgtcgtcc tcgtcggcca
     8101 ggcccacgac gtagatgtcg catcccgcct cccggaggcc ctccgcggcg ctcagcagga
     8161 tcgaggccac ctcctcgcgg aagccgggcc gggtctgcat cgatgccagg cagccgtagg
     8221 tcacaccggg ttcccgtctc ctcgggcgga ccggacgtcc gccacggcag gaccctgcca
     8281 cacccccacg aacgcgacgg gcgccggccg gaacccgggg gacgggtggg gcggtttccc
     8341 tgccgtgggg cgtgcgggca ggtcgtgagt gcggcgttcg cctcatcagg gaggtttgtg
     8401 caccttgacc gcaagaccgc ccccttcacg ccgtatccga aggatgtccc gacactggtt
     8461 gtcttggcgt tgcgcacggc cacctcgggc accaccggtc gttcccgctc acttctgctc
     8521 gttcgcctgg gaggccacgt gtccgctccg gacagtgtca cgggtccggt caccgacgaa
     8581 tccggacccg cggcgcccgc ggagaacccg ctcaccagtc tcagcacgca cgccgcacgc
     8641 cagttggcga ccacccacaa gtccgagccc cagatgcggg gcatctcctc gcggtggctg
     8701 atcaggagac ttccgtgggt ggacgtgggg ggcggcacct accgcgtcaa ccgccggctg
     8761 cacctcgggg tcggccgcgg acgggtccag ttcgagcaga acggcgccga cgacgtccgg
     8821 gtgattccgc ggacgcttgc cgagctgccg gcgctgcggg gctacgcgga ccacgacgtc
     8881 ctcgaagagc tggccggccg cttctcggtc cacgaggtcc gggcgggcca ggtcctgcac
     8941 gaggcgggcc ggcccgtcac cgagatcttt ctgatcgtgc acgggcgcct cacccggtac
     9001 acggccggca ggtacggcga ggaagaggtc ctcggggtag tgaccgacgg cgaccatgtg
     9061 ggcgacgagg ccatcggccg gtccgacccg ctgtggcaga cgtcggtgcg cgccgagacg
     9121 gccggcgtgg tgctggcgct ggcacgggac gacctccgtg agctcaccgg ccgggcgccg
     9181 tcgctcgccg cccacctggc cgcccacacg gagcggcagc gcctgccggt gaaccgccgg
     9241 ggcgaggccg acgtccccgt gcggtccggc cacagcggcg agcccacgct gccgggcggc
     9301 ttcgtcgact acgagctcac gccgcgcgag tacgagctgt ccctgaccca gaccgtgctg
     9361 cgcgtgcaca ccagggtcgc cgacctcttc agcgacccca tggaccagac ccggcagcag
     9421 ctgcggctga ccatccagga gatccgcgag cgccaggagt gggagctcgt gaacaaccgg
     9481 gacttcggcc tgctgcacaa cgtcgatcac ggccagcgca tcagcacgtc cacgggcccg
     9541 ccgacacccg acgacatgga cgaactgctg tccatgcgcc gcgcgacccg gctgttcctc
     9601 gcccatccga aggcgatcgc cgcgttcttc cggcagtgca acaaacgcgg tctggtgccc
     9661 ggttccgcca cggtcaacag gcaccacgtc cccgcgtggc ggggcgtccc gatcttcccg
     9721 tgcggcaaga tccccgtctc cgggtcccac acgacgagca tcgtcgcgat gcgcacgggc
     9781 gagtcggacc agggcgtcgt gggtctgtac cagaccggaa tccccgagga gtacgagccc
     9841 gggctgaacg tccgctggat gggcgtcaac agctccgccg tcgtcaacta cctcgtgacc
     9901 gcctactact cgctggccat cctcgtaccg gacgcggccg gcgtcctgga gaacgtccag
     9961 ctcggccgtg tcgccgactg accgggtgga gcccctgacc atgagtacca ccgacaaccg
    10021 cacgcccgcg ttctcgctgc cgggcccgcc gagtcccgcc cggtccctgc gcgcccgggg
    10081 cgacaccgcc gtcccggggc tcaggtaccg tccggtcgcc cccgccgacc cggagaaggc
    10141 cgccgagatc gaccgcagac tcgaggcctg ggcccgcgcg ctcgacctgt tccccccgga
    10201 gtggagcggg gacttcgcac agttccggtt cggccgcgcc gtcgctctcc agcaccccga
    10261 agcggccgac atggagcgcc tcaccgtcgc cggcaagctc ctgctggccg agaacatcgt
    10321 cgacagctgc tactgcgagg aggacgaggg caggggcggc gcccggctcg gtctcggcgg
    10381 gcgactgatc atggcccagt ccgctctgga tcccctgcac agcacgcccg aggccgagga
    10441 gggctggcgc gtcggcgtcc aggccgacgg tcccctgcgg tcgtaccact gggccctgaa
    10501 ggactactcg gccgtcgcca cgcccagcca gaccggccgg ctggtgcacg acctggcccg
    10561 gctgcacatg ggctatctcg ccgaggccgc ctgggcccag acgcgtcacc tgccgcgcgt
    10621 ctgggagtac ctggtgatgc gccagttcaa caacttccgg ccctgtctgt ccatcgtcga
    10681 tgccgtggac ggatacgagt tgcccgaagc cgtctacgcc cgccccgaga cgcagcggat
    10741 caccgccctc gcctgcaacg ccacgaccat cgtcaacgac ctgtactcct tcaccaagga
    10801 gctggccagc gaccccgagc acctgaacct gccccaagtg gtcgccgcga acgaccagtg
    10861 cggactgaag accgcctatc tgcgcagcgt cgacatccac aacgagatca tggaggcatt
    10921 cgagacggag tccgcgctgc tgtccgagac ctcgcccctc gtcgagcgat acgcccgggg
    10981 gctcgccgac tgggtctccg gcaaccacga atggcacgcg agcaacaccg agcgctacag
    11041 cctgcccgac tactggtgag cggcattccg caccaccggc agacggcaga acggaacacg
    11101 caccacagct acagggagcc atcgttgacc accgcccaca ccggcacgac ccccgtaccg
    11161 gtccccactc agtccacgta ccagaaccgc gtcgcggagt actggaacgc cgaggagaac
    11221 ccggtcaacc tcgaactcgg cgcactcgac gacctgtacc accaccacta cggcatcggt
    11281 gacgccgaca ggtcggtact ggacgatccg gacccggacc agcgccgcga gcggatcacc
    11341 catgaactgc accggctgga gcacagccag gcggagttcc tcgcctcccg cctcgggaac
    11401 gtctccccca ccgaccgggt cttcgacgcc ggctgcgggc gcggcggcgg cagcatcgtc
    11461 gcccacctcc gctacggctg ccacaccgac ggggtgacca tctcccgcaa gcaggccgac
    11521 ttcgcgaacg agcaggcccg caagcgcggc gtggacggca aggtgcgcta ccaccaccgc
    11581 aacatgctcg acaccggtct cgacaccggc gcctacgcgg cctcctggaa caacgagtcc
    11641 acgatgtacg tcgagctgga cctgctgttc gccgagcact cgcgcctgct gcgccgcggc
    11701 ggccggtacg tggtgatcac gggctgctac aacgacacct acagtcaggc gtcgcgcgag
    11761 gtgtccctca tcaacgccca ctacatctgc gacatccacc cccgctcggc ttatttcaag
    11821 gccctggcac gcaaccgtct cgtccccgtc cacgtccagg acctcaccgc ggcgaccatc
    11881 ccctactggg aactgcgccg caacgccgag cacctcgtca ccgggatcga ggacaccttc
    11941 ctcacggcgt accgcaacgg cagcttccag tacctgatga tcgtggccga ccgcgtgtga
    12001 cgttatttcg ggccggggcg gggggagtga cggccggcgg acggtgccgt ccgccggccg
    12061 tcggtgcggt gtcgccgtcc cgtaggcgat ctgtcggtga ccgctgcgag cgtgggcgtc
    12121 gagccggccg gcgaacagcc gcagccgtcg tcgtcagcga agggtccccg ccgtcatgcc
    12181 gtccacatcc cccaccccgc cctggaacgt ccaccggctg ccccgtgccg acggccgcgt
    12241 cttcctgatc accggcggca acgccggcat cggctacttc gccgcggagc agctgtcggc
    12301 gacgggggcg accgtcgtcc tgggcagccg ggaccccggg aaggcgcggg ccgccgggga
    12361 ttccatccgt gcgcgggtcg ccggtgcgcg agtgcgggcc gtccggctgg acctcgccga
    12421 cctctcgtcg ctgcgcaccg ccgtggagtc gctcggagtg gcgcacctcg acgcggtggt
    12481 gcacaacgcc ggcgtcgccc tcgacgaccc gccccgcacg gagacggtgc acggacacga
    12541 gctgatgttc ggcacgaacc acctggggca cttcgccctg acccactggc tgatgccgct
    12601 gctgtcggcc gcgccggcgg cccgcgtcgt caccatgggc agcttcgcgg cgaagtcgga
    12661 acggctcgac ctggatgacc tgcagtcccg ggcggactac cggcccaaac gcacctacgg
    12721 acgctccaag ctggcgcaga tgtacttcgg tgtcgaactc gaccgccgcc tgcgtgccgc
    12781 cggctccacg gtgcgcagcg tggtggtcca tcccggcggc gcgctggact cgctcacccc
    12841 gtcacgcccg cccgtccagg tacggaacac cggcgcgcgg ttgcgtgcgg cgcctgccgc
    12901 actcctcgtc cagggcaagg acgccggtgc gtggcccgcg gtccgggccg tgctcgaccc
    12961 ggccgtggac ggcggccagc tgtgggggcc gcgcgtgttc ggcctgcgcg gtctgccccg
    13021 gcgcgaaccg ctgtggcccc agctcgccga ctccggggtc gcggcgcggt tgtgggacgc
    13081 gagctgcgac ctgaccggca ccgctcccgg accggaccga cgggaggcgc cgccgcacgg
    13141 ggcgtagccc gccgagcacg gtcacggcat cggccgcggt atcagcctcc gtggacggtg
    13201 agccggtagc cctcggggcc ggtgaaggcg aaggtcggcc cgaagggact gtcctgcacg
    13261 ggcccggcga cgtcgactcc cgcggcgacg agctgtgcgt gcagttgatg ggcgtcgtcg
    13321 gtgcgcagcc acagcgccac cccgaggccc gggacggcgt ccgcggagag gtcggtgccg
    13381 gggagcggct cacggacggc gaaggggatc ggcgcggtgc cgaagacgac ggcacccggc
    13441 ggcgagacgg gggcgcgccg caggccgagg tgctcctcga agaaggcggc ggccgcgggc
    13501 acgtccgtga cctgcagggc gatgaagtcg ggaccctcga cggtggcggt catggttcct
    13561 ccaggaactc tcaatgtcag gactttgaca tagaggactg taggcgcccg gggcgacgca
    13621 tgtcaaaatg ctgacatgac cgaacggacg cccgtccccc cgcctcatcc cgcccaggac
    13681 gtcaccgaac acgtgggata ccgcctcaaa cgcaccgcgg ccgccctgcg cggcgccatg
    13741 gacagagcgc tgcgcgagca cgggctgacc gtcccgcagt actcctgcct ggagctcctc
    13801 gacgagcggc cgggcctgtc caacgccgac ctcgcccgcg gcaccttcgt cacccggcag
    13861 tccgccaacg tggtgctgcg cggtctgggg gacgccgggc tgatcacccg gccggcaacc
    13921 gccgatcacg gtcgcgccct gcccgcgcac ctcactccgg cgggacgcga acgcctgcac
    13981 gccgcccgcg gcgccgtcta cgccgtcgag gcacgcatga tcaccggcgt gccggccgac
    14041 cgcctgccgg ccctgctcgc cgacctcgac gccatgaccg aggccctcgg cgactgacgg
    14101 acgctccgag gcgcccgacg gaggcaccga tgagttctgc ggggcgggcg ggtccctcac
    14161 ggtgacggca gatcacagtc cacgaacagg agttcttctt ccatgactga tccggcgacg
    14221 accacggaac accaccgcga aggcggggtc tgggcccgcg tccacaccga acgggcggcg
    14281 ttggcggccg acctcgcggg actgacggac gaggagtggg caacgccttc gctgtgcgcg
    14341 ggactgacgg tgcgcgaggt gctggcgcac ctcacggcgg gtgcgagcct gaacaccgtg
    14401 aagtggctgg ccggtgtcgt ccgctgccgg ttcgacttcg acaagcaggt ggccgtgcga
    14461 ctggccgagc acctgggcac gacccccggc gagaccctcg aacgtttccg gcgcgtcgtc
    14521 tccagcacga ccaagccccc cttgccggtg gtcgcgatgc tgggcgagac gatcgtgcac
    14581 ggggaggaca tccggcgctc actgggcatc cgccgcgcgc agcccgtcga ggccgtcacg
    14641 gaggtggccg agtactaccg gggctcggac ctcgtggtcg aggccaaggg acgtatcggc
    14701 ggtctgagac tcgtggcgga cgacggtccg ttcacgaccg gctccggggc tctcgtgtcc
    14761 ggccccacgc tgtcgctggt gatggcgatg acggggcgcg cggcccactg cgacgacctc
    14821 gcaggcgacg gggcggagat cctccggggc cgctgcgggc ccgcctgaca cggtgtcgtg
    14881 gcgaccggcc cggacgcaac cgtccgggcc gcggtcccgt cgcggtacgc ccgcgccgtc
    14941 actccgcggg aacggcggcc cccgccggat cgtccgggtc cggcgtgtgg ggaagcgggc
    15001 ccacggagcc gccctcccag agcagcacgt gccatccctg ctcgggcgag ccggtgagga
    15061 tgacgacgcc cgtgttcgcc agggcgtgcc gggcggcgta gtcgacgtcc acgttgtcgg
    15121 cccgcgccgc cacccacatg cggatcgcgg caccgtggct gaccatggcc accgtccccg
    15181 caccgctctc gtacgcctcg gcgacgacgg cgtcgtagcg ccccagcgcc tccacgccgt
    15241 cctcgccgcc gggcatgcgg agccccacgt cccccgccga ccaggcgaaa gcggtccgca
    15301 gataggtgcg ggccgcctcg tcgtcgccgc gcatctccag atcaccggcg atcagttccc
    15361 ggataccggg gcggacgcgg acgtccagtc cggtggccga ggccagcggc gcggcggtct
    15421 cccgggtgcg tacgagcgtc gacgcgtaca gggcgtcgat cctctccgac gccagcgcac
    15481 cgggcagcgc cgcggcctgt tcctctccga gggccgtcag accggggccg ggctccgccg
    15541 tgtccaggag gtgcttgagg ttggacgggg tctggccgtg cctgatgagc aggagacgca
    15601 tgcgaagagg gacctcctcg ggaccgggtg acgacgcggt ggcgggctca cctccactct
    15661 gccacgctcc gcggccggcc cgcgtgcagg cacccccggg ccccggcgct caccagtcgt
    15721 ggacggtacc gtcgccgagc cggttcacgg gcaggtaggc gggccggtag ggaaagcgtg
    15781 ccgcggcctc gtcgtcgagt tcgacgccga ggcccggggc gtcgcccggg tgcaggaggc
    15841 cgtcctcgaa gcggtaggag gtatggaaca cctcaagggt gtccggggca tggcgcatgt
    15901 actcctggat gccgaagttg tgcacggcga ggtcgagatg gagggcggcg gccataccga
    15961 cgggcgagat gtcggtcgga ccgtgcatgc ccgacctgat gccgtacacg gccgccatgt
    16021 cgagcagttt ccgtaccgcg gtgatgccac cggtgtgggt caccgccgag cggacgtagt
    16081 cgatcagccg ttcctggagc aacgtggtgt agtcgtggac cgagttgaag acctccccga
    16141 tggccagcgg ggtggtggtg tgttcgcgga tcaggcgcag cgccccctgg tcctcgcccg
    16201 gtgtcgcgtc ctccagccag aacaggtcgt agggttccag gtccttcccg agccgagccg
    16261 cctggatcgg cgtcatgcgg tggtgtccgt cgtgcagcag ggggagttcg gggccgaagg
    16321 tgttccgtac cgcttcgaac accgtgggca tgtggcgcag gtaggcgcgg gtgtcccagg
    16381 tctcctcggt ggggcgcggg tgcgcggcgc gggtgcggcg ggcgggctcg tagtcgtagc
    16441 gttccccgtc accggcggcg gaggcggcga cgccgtacac ggagtcgaga ccggggatgc
    16501 cgctctggat gcggacggcc cggaagccgt ccgccaggtg ctcgcgcacg gagtcgagca
    16561 gttccggtac gtcccggccg gaggcgtgtc cgtaggccag cgcgcccgtc cggcaggcgc
    16621 cgccgaggag ttggtacacc ggcaggccgg cggccttgcc cttgatgtcc cacagcgcgg
    16681 tgtccacggc ggctacggcg gccatggtga ccgggccccg gcgccagtag gcaccccggt
    16741 acaggtactg ccaggtgtcc tcgacggcgt gcgcgtcccg tccgggcagc agaggggcca
    16801 cgtgttcccg cagataggcc tcgacggcca gctcgcgccc gttgagggtg gcgtcaccga
    16861 ggccggtgag tccgtcctcg gtggtgatgc gcagggtgac gaagttgcgg ccggggctgg
    16921 tgacgacgac atcggcggcg gtgatcttca cgggatccgt cctcgggtgg tcggaaacgg
    16981 cggccaggcg ctgctgcacc cggccgcgcg ttccgcacgg agcgtgcggc gcgcccggcc
    17041 ggggcccacc ctagggtccg tcttcacatt cccgtctgcc aggcgacgac agaccctagg
    17101 ccgtgcgcgg ctcggttcag cgcccgcgca gccgctcggc cagggccgcg agcgtccggg
    17161 aggtctcggt caggctcgcc gctgcggcct cgagttccgg agcgagaccg ggatcggcgg
    17221 aaggcccgga gggctcggtg gccgccggcg tgccgcggta gccgatgggg ccttcgtcgt
    17281 ggcgctggta gtagcccgtg aaggactgcc cgtcgggcgc ctccgcgaac cggacaccgg
    17341 cgagctgggt ctcgcccgca ccggcgttgc ggaggatgtc gagacggtag tggcggtacg
    17401 cccgggcgcg gccgcggagg gtgaactgcc tcgactccca ccgcccggcg aacgtctccc
    17461 cggtgcgggc gtccaacggc gtccagttgc ggccgtcgcg ggagccgtgc agtctccagt
    17521 cgcgggggtc ccggtcgggg gcgtcgttcg ccgacgtcag ggtgtaggag gcgactgcgg
    17581 cggggcgggc cagggtgaag tcgagccgtg cggtgtcgtc ccatgccagc cacttggtgc
    17641 gctcgcccgc caggaggttg tccgccccct ctcccccgtc gtcgaactcg tcgctcgcgt
    17701 cgacgtccgt cacctcgacg tccctgtgga cggtgtgcag cacggccgag cccgagttgc
    17761 cgcgccggtc gcgccagtgg accccctcga cgggtgctcc gccgtcgtcg accaggagcc
    17821 gcaggtcgtg ggagcggtgc cagccaccgc cccacccctc ctccgtgcgg aagcggtgca
    17881 gggggtacgc cgagaggtgc tccgtctcgt ccgagaaggg ccaccggtcg gtgaggtcac
    17941 cccggtactc gtacgcggta ccgtcctccg cccggtagca gccgcggaag tccgccatgc
    18001 cggacgcgaa gccgatggtg gcctcggccc cgtcctcgcc gcgccagccg agctgcgcgg
    18061 gcagggactg ctcgccccgg tcgagatgga agagcagccg cggtgcggac tgccaggggg
    18121 cggaggaggc atgggccggg cgcagctccg tacggtaggc gaacaccgag tcccgagcgg
    18181 ctccggccgt gcgggcccgc tccgagcggc cgcgttcccg gacggggtcc agggtgaccc
    18241 ggtacagcca gagcatgctg gcggccttgg gggaggagcg tatctccagc ctgttggtgc
    18301 cgggcttcag caggtctccg ggtacggcga ggacgttgtc gtggggcaga tcccctccgc
    18361 cgggcacggt caggtcctgg gccagcgtct cgccctgcag gcgcacggtc atgggcgcgt
    18421 acccgagcga ggatccgagc ttggagacga gggccgtgac ggtgagcgtc gcctgcggga
    18481 cgtcctgcgg gtcctgcacc tcgaagtcca gcgtcaccgc cccgtccgcg cccagtgcca
    18541 catgggaccc ggcgaagccc ccaccgtgga acccggcctc cgcgttcgac agtcggggcg
    18601 gatcgaccga gaaatccgcg tacgtcgctt caaagcccat gcgtactcca taagttgatg
    18661 gcccgtcacc tcggcccgcg ctcgacggcg ccgaccgtga tgacggacct tagcccccag
    18721 gaccgacaac gcggacggcg gaggacgcgg cggcgaggcc cggccgacgt cagcgccccg
    18781 gcccggaccc gggtcggtcc gccggcccgg caccgttcgc gagggtgcgg gcgcagccac
    18841 ggtccgctga tgtctccggc atgaagcgcg ccgcgatgac gacgacgtcg gagagtgtcc
    18901 cggcgcgctc gggccgcctt cccgtcggcc tcacttcagg tgccgggcga agaaccgggc
    18961 cgcggcctcc ccctcgtact gcggcacgcc ggtgtgtccg cccatgttgg cgtgcaggga
    19021 cttctcctcg gagccgaagg cgtcgaacag gtccagggcc gcctgccggt cgttgccttc
    19081 gtcgtcccac tgcagcagga cgtgcagcgg aatggtgacc cggcgggcct cctcgaacat
    19141 ggcccggggg acgaggcttc cggcgaagag gccggcggcc acgatgcgcg gctcgaccac
    19201 cgccagccgg acgccgatgg agaccactcc ccccgagtag ccgaccgggc cgccgatctc
    19261 cggcagtgcg aggagggcgt ccaggcaggc ctgccattcc ggaaccgcct cgtcgaccag
    19321 cgggaggatg agggcgtcga cgatctcgtc ggtgaccggc tctccggcct ccacggcccg
    19381 gcgcatccgg gcgcgggcct gctccgcggc gggccgacgg ggccggtcac cgctgccggg
    19441 aagctcgatg gtggccgcgg cgaagccgtc cgtcgcggcg tgccgggccc gtcccaccag
    19501 ccgggggtac accctgcgca gtccgagcgg cggggggccg agcagaatca gcggaaccgg
    19561 tgcggacgcg gccgcgggcg tccacaggat gccgggaatc ccgtcgaggg tgaattcacg
    19621 ctcgacgacg ccgtcgtcga gacgtcgttc ggaagtgatg tgcatggtcg tgcctttcgg
    19681 gagtgctcat gaacggcgct cccggacgac ctaccgcccg accgtgactc ctgcggagag
    19741 cacccatgtc gatactgcgt tcacgggtac cacctcctcg ttctctcgca cggcctccgg
    19801 aaaggtagca gcggcagccg cgggccacca agcgggtttt ccccggggag gcgggtgcgg
    19861 tggcgtcctc ggagggcgcc gggtacgcac ttgtacgcac cggcgtccgt cgccgccgcg
    19921 cggaggcccg caccggccat agggtgacca ccggtttcgg ccctcgcgcc accgctgccc
    19981 ggccgcgccc gccgatcgct ctcccggtcg tccgcctgcg aattgacagc cgatcggggg
    20041 cgcgtttagc ttctcgccat gaattaccga acaaatgttc gcacggagcg tcggcgagaa
    20101 ggatcgaaag gcggcccctt caccgtctcg ctgacagggc agtggcttgt cgtcgccctg
    20161 ttcgcctcgg cgatcgcgat actttcccgc cgccaagaag gaaccttcct ctggatcggt
    20221 tccgtactcg gcctggcggc cgcggcgggc ttcttcgtgc aattcgattc cgtcgcgaat
    20281 tggcggcgcg gcctgctctg cgcactggcg ctcctcctgg gtgccatgtt caccctgcag
    20341 gtcttcatcg cactcttcac cgactgacgc gtctcccggg ggaaaacatg tcgtcgatcg
    20401 ttcccatggc attcctgctc atcctgttga tcctcctggc aggcttcgtc gccgcccgga
    20461 gggggcggcg gaagctgatg cgcgacatcg gcctggtcac cgcctactgc cgtcggcagg
    20521 ggtggcagca ggcgccaccc gaccgggaca tcaacgcacg caccctgctc ctcttccagg
    20581 ccacggggac cacccggctg cgcgtgcagg cgcagtacgc cggccggtac cggggcgtgt
    20641 cctttcaggc cgcgcaggtc gcccgccctc cgcggcccgg gcgggtgacg gcacagtggg
    20701 tgtctgtcgt ctaccttccc cgcccggtcc cgggtcccag agtccagttg gccaagcgcg
    20761 gactctcgtc ggcgaacttc ctgagcggcc ggaccacgat cgacaacggg ccgttcgacg
    20821 cgacgttcca cgtcgtggcc gaggacgagg cgttcgcacg gtccgttctc cgtccctccc
    20881 ttgcgggagc cctgtgcggg gacgcgcggg cactggacgg cgtggtggct ctcgaacacc
    20941 accatctgtt cgccctgcgg cacgggcagc tcacccccga gaagctgcgg gccatgctcg
    21001 acctcctcgt ggacatcggc tcgtccgtcg actggcaggc ggcgcccgcc caccgtccg
//
