LOCUS       NZ_WHZR01000001        24046 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. OM5714 A912_AS4_SC1_R2, whole genome shotgun
            sequence.
ACCESSION   NZ_WHZR01000001
VERSION     NZ_WHZR01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. OM5714
  ORGANISM  Streptomyces sp. OM5714
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915160)
  AUTHORS   Samborskyy,M.
  TITLE     Whole Genome Sequence of the phthoxazolin producer Streptomyces sp.
            OM5714
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915160)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2019) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: OCT-2017
            Assembly Method                   :: Newbler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 102.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010993835.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:48:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,730
            Genes (coding)                    :: 7,557
            CDSs (with protein)               :: 7,557
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 7, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 7, 5 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 58 of 173
            Pseudo Genes (incomplete)         :: 139 of 173
            Pseudo Genes (internal stop)      :: 18 of 173
            Pseudo Genes (multiple problems)  :: 36 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7566173
            Orig. end                         :: 7590219
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WHZR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24046
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="27"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24046
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24046
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14046]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14046
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(180..196)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.91"
                     /tool="antismash"
     misc_feature    560..575
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.32"
                     /tool="antismash"
     gene            631..1953
                     /locus_tag="STPH1_RS33810"
                     /old_locus_tag="STPH1_6705"
     CDS             631..1953
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446464.1"
                     /locus_tag="STPH1_RS33810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6705"
                     /product="cation:proton antiporter"
                     /protein_id="WP_164385942.1"
                     /transl_table=11
                     /translation="MGHADTLLAMGGAFVAAAFFARLGGRIGLPTIPLFMLAGILLGPH
                     TPGFVLVEDAHDFEMLSALGLVLLLFYLGLEFHLDDLRSGGKRLLTAGGVYLLLNVGAG
                     LGFGLVLGWGAREALVLAGVLGISSSAIVTKILIDLGRIGRPETRLILGVIVVEDIFLA
                     LYLAALQPVIAGAHGVADTVLQAGKAFGFLLVLAAAARYGTRLVGRLIDTRDNELLVIS
                     FLGAAVLVAGVSELLGVADAIGAFMVGLILAGTPSGPRIRELVQPLRDAFAAIFFFAFG
                     LAIDPGDLASVAGPVAAAAALTVVMNVVAGLCVARVYHYGSEPAAEIATTLVARGEFAL
                     ILAAMAAGAGLDARLAPFIAGYVLVLAVLGPVVAGRAHVLAAALRAAGRLLPGATAPVP
                     VPVPGDGNGGRTEADSLPVPAEVSSSPGSPPSSPERAEAER"
     gene            2102..2545
                     /locus_tag="STPH1_RS33815"
                     /old_locus_tag="STPH1_6706"
     CDS             2102..2545
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031627.1"
                     /locus_tag="STPH1_RS33815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6706"
                     /product="hypothetical protein"
                     /protein_id="WP_153181324.1"
                     /transl_table=11
                     /translation="MIEWVPLGSGARPVPRPVSAPLVWAGAFGGALLLVALLNGTVGSG
                     RPGFALVALSLLAALLGLCARFTAAPGTAVLCWLSLNGFAIPPAGTLTWAGPRDAFWLA
                     CLLGAALVGTALARVVHARAAYRRLTTATGLDAPEPGTGPGDV"
     gene            complement(2722..3900)
                     /locus_tag="STPH1_RS33820"
                     /old_locus_tag="STPH1_6707"
     CDS             complement(2722..3900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031628.1"
                     /locus_tag="STPH1_RS33820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6707"
                     /product="S1 family peptidase"
                     /protein_id="WP_164385943.1"
                     /transl_table=11
                     /translation="MRRSRLRHLGLAGLLVLGGLTAAGTLPASAADASSTSPSASTDRQ
                     PASAGLLDAMQRDFDLSRSEAEDRLAAERDATGLEPVARRAAGTAFGGSWFDPDAGELT
                     VALTSDAAPSTVRAVRATGAQVRTVEHSARQLDAAKARVDRLDAPAGVSSWRVDHSANT
                     VVVDVVESERADNDVQSFLERAREAGPVTVRSVPSAPQTFAAGTVGGDPYYTGNVRCSI
                     GFSVHGGFVTAGHCGRAGAGVSGWDGSYIGTFQGSSFPDNDYAWVSVGSGWWTVPVVLG
                     WGTVSDQLVRGSNVAPVGASICRSGSTTHWHCGTVLAHNETVNYSDGSVVHQLTKTSVC
                     AEPGDSGGSFISGDQAQGVTSGGWGNCSGGGETWFQPVNEILNRYGLTLHTA"
     misc_feature    complement(3965..3979)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     misc_feature    3966..3980
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 27.13"
                     /tool="antismash"
     gene            4167..4673
                     /locus_tag="STPH1_RS33825"
                     /old_locus_tag="STPH1_6708"
     CDS             4167..4673
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-141). E-value:
                     3.3e-10. Score: 32.5. Matches aSDomain:
                     nrpspksdomains_STPH1_RS33825_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031629.1"
                     /locus_tag="STPH1_RS33825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6708"
                     /product="SRPBCC family protein"
                     /protein_id="WP_153181326.1"
                     /transl_table=11
                     /translation="MAVRHRLIQATPEAVWDVLADGNTYVEWVVGPSEVTPRAGQWPRV
                     GATIAYEVRLGPLRLHNESVVRRCVEGSELELEAKAGRLGTARIAVELRPWGEQCLVIV
                     DEHPLRGPGGLLHNVGVEALIQVRHRAMLARLAKLCESEAGDRCRPDPPDVLGPVGHRP
                     GTGRA"
     aSDomain        4176..4589
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STPH1_RS33825_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.30E-10"
                     /label="STPH1_RS33825_Polyketide_cyc2.1"
                     /locus_tag="STPH1_RS33825"
                     /protein_end="141"
                     /protein_start="3"
                     /score="32.5"
                     /tool="antismash"
                     /translation="RHRLIQATPEAVWDVLADGNTYVEWVVGPSEVTPRAGQWPRVGAT
                     IAYEVRLGPLRLHNESVVRRCVEGSELELEAKAGRLGTARIAVELRPWGEQCLVIVDEH
                     PLRGPGGLLHNVGVEALIQVRHRAMLARLAKLCE"
     gene            4666..6303
                     /locus_tag="STPH1_RS33830"
                     /old_locus_tag="STPH1_6709"
     CDS             4666..6303
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446458.1"
                     /locus_tag="STPH1_RS33830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6709"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_164385944.1"
                     /sec_met_domain="DAO (E-value: 1.9e-08, bitscore: 32.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAPDAVDAVVVGAGPNGLVAANLLADAGWSVTVLEEQPEPGGA
                     VRHDGEVAPGFVNDLFSSFYPLAAASPILGGLRLEDHGLRWAHAPHVLAHPLTDGTCAV
                     LDRDVATTAASLDAFAPGDGAAWERLHAVWDRYRADIVDALFTPFPPVRAGARLALRLR
                     GAGGLRLARTLVLPVRRMGEEEFRGEGGKLLLAGNALHADLAPEAAGSGGFGWLMSMLG
                     QTYGFPVPVGGSGALTGALVHRLRARGGTLHCGRRVERVLVRDRRAVGVRTADGETVTA
                     RRAVLADVSVPALYGGLVPPADLPDQVLADLRRFQWDFATFKVDWALDGPVPWRCEAAA
                     RAGTVHLADGLDELTRFAAQIAMRQVPDRPFSLFGQMTTTDPTRSPSGTESAWAYTRVP
                     HDIRADAGDEGITGSWDTRERELMADRVERHVERFAPGFRALVRARRVLAPPALQAMDA
                     NLEGGAINGGTTAMHQQLVFRPVPGTGRPETPVAGLFLASAGAHPGGGVHGAPGANAAR
                     AALRQHRFAGLARVQRALTRRDRAGDRC"
     gene            6362..7240
                     /locus_tag="STPH1_RS33835"
                     /old_locus_tag="STPH1_6710"
     CDS             6362..7240
                     /NRPS_PKS="Domain: PKS_KR (9-180). E-value: 1.3e-16. Score:
                     52.9. Matches aSDomain:
                     nrpspksdomains_STPH1_RS33835_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446456.1"
                     /locus_tag="STPH1_RS33835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6710"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_164385945.1"
                     /sec_met_domain="adh_short (E-value: 4.4e-33, bitscore:
                     113.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSPLQNRTVVVTGAARGLGAAVARACARRGARLALLGLEKPCL
                     DALAADLPTPALAVETDVTDPAALADAADETRRRLGKPSVVVSNAGVAHGGPFATSDPA
                     EWRRVVDVNLTGSAHTARAFLPDLLDTAGYHLQIASLASLGAAPLMSAYCASKAGVEAF
                     THSLRAEVAHRGVAVGIAYLNWIDTDMIRDADRYPVLRELRAHMPPPARRTFPPEDVAA
                     RLVRAVERRRTAVYVPGWLRLVQLGRVTLPPAVVRLSRHELPRMEAEEALDHTGPLGAG
                     GLADRAADPRQ"
     CDS_motif       6389..6478
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STPH1_RS33835_0001"
                     /evalue="4.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="STPH1_RS33835"
                     /protein_end="39"
                     /protein_start="9"
                     /score="19.2"
                     /tool="antismash"
                     /translation="TVVVTGAARGLGAAVARACARRGARLALLG"
     aSDomain        6389..6901
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STPH1_RS33835_PKS_KR.1"
                     /evalue="1.30E-16"
                     /label="STPH1_RS33835_PKS_KR.1"
                     /locus_tag="STPH1_RS33835"
                     /protein_end="180"
                     /protein_start="9"
                     /score="52.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVVVTGAARGLGAAVARACARRGARLALLGLEKPCLDALAADLPT
                     PALAVETDVTDPAALADAADETRRRLGKPSVVVSNAGVAHGGPFATSDPAEWRRVVDVN
                     LTGSAHTARAFLPDLLDTAGYHLQIASLASLGAAPLMSAYCASKAGVEAFTHSLRAEVA
                     HRGVAVGI"
     gene            complement(7269..8771)
                     /locus_tag="STPH1_RS33840"
                     /old_locus_tag="STPH1_6711"
     CDS             complement(7269..8771)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144561.1"
                     /locus_tag="STPH1_RS33840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6711"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_205616859.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.4e-07, bitscore:
                     27.0, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 5.3e-11, bitscore: 41.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLCPGPGRERVEGGAPSVAVIGGGIAGLAAATVLAERGVRVVLYE
                     REPVLGGRVSGRTFALPDGTPATMSRGFHAFFRQYYNLRGLLRRGDPGLAMLTGLPDYP
                     LRHSSGLHDGFRRIPRTPPFSALAFVALSPSFGLRDLTSLRPSAALPLLDVRTRRVHER
                     LDDLSAHDFLDSLRFPPAARHLAFEVFSRSFFADPRELSAAEMALMFHIYFLGSSEGLL
                     FDVPREPFPQALWDPLAGHLARHGVEVRTDTAVEAVRPGPSGGRLVVDAAGARPYDAVV
                     LAMDVGGLRDVVSRSPHLGDAGWRTRVARLRNAPPFLVSRLWLDRPVAPGRPGFLGTSG
                     YGSLDNVSVLSHWEGEAARWAARTGGCVVELHAYAVPSAAVREVEEKRLVDQLHRVYPE
                     TRRARVVAARHEWRADCPLFTVGGYRDRPTVRTPDPAVVVAGDLVRTDLPVALMERAAT
                     SGFLAAGALLERWGVRGETLWTVPDRGRSAPLRALARRFGAH"
     gene            complement(<9194..9955)
                     /locus_tag="STPH1_RS33845"
                     /old_locus_tag="STPH1_6712"
                     /pseudo=""
     CDS             complement(<9194..9955)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324137.1"
                     /locus_tag="STPH1_RS33845"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6712"
                     /product="methyltransferase domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="PCMT (E-value: 0.00015, bitscore: 20.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLRDAALTTAFDRGAGRYDRLVALNPGYHSQLRRSARRLGLAD
                     GGAGGRVLDLGCGTGASTAALAAAFPAAEIVGVDASAGMLERARAKRWPSRVRFVHAAA
                     EDLDLEDLDLEDLDREDLDREGLDRAEVRGPFDAVFAAYLFRNVSDPDAVLRSVRRMLV
                     PGGRLAVHEYALGGRRGNRLVWDAVCRAVILPLGTATGDRELYRHLWRSVAAFDTAPAF
                     GARLGRAGFAGVRVLPLPGWQTGITHTFVGRR"
     gene            complement(10001..11203)
                     /locus_tag="STPH1_RS33850"
                     /old_locus_tag="STPH1_6713"
     CDS             complement(10001..11203)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982459.1"
                     /locus_tag="STPH1_RS33850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6713"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_164386602.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 2.6e-90, bitscore:
                     302.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDAEIVVVGAGAAGLSLVHRLPAAAPPGAASSVVLVDPPPGPLR
                     PPRRTWCFWEAGCGRFDRAATATWEWLRVHGRDGTVVRRHIAPARYKMIRSDDFEALVE
                     RDLKDRPGLRRVEATVGAVTVLPDATVRVAATDASGAPVGLRARWVFDSRPPDRLPAAR
                     TRLLQHFRGWFVRTERPAFDPGVVDLMDFRTAQPRRGLSFGYVLPTGRHTALVEYTEFG
                     PAPLTTEAYDGALEDYTRRVLRTGAMEVLSTEQGVIPMTDAIFERRAGGCDRVFRIGVA
                     GGATRASTGYTFAAVQRQSEAVARAVRAGRRPVPPPPHPARARWMDAVLLRALDTGRVD
                     GPDLFFRLFDRVPAARLLRFLDGGSRLSEDLAVGVRVPVLPMLRTAAELPWLPRRHLPV
                     R"
     gene            11537..13054
                     /gene="crtI"
                     /locus_tag="STPH1_RS33855"
                     /old_locus_tag="STPH1_6714"
     CDS             11537..13054
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004992099.1"
                     /locus_tag="STPH1_RS33855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6714"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_164385946.1"
                     /sec_met_domain="DAO (E-value: 2.6e-17, bitscore: 62.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTVPGRTDHVVVVGAGLAGLAATLHLLGAGRRVTVVERDPLPG
                     GRAGRRALGGYHLDTGPTVLTMPDLADEAFAAVGERLRDRVELLPLHPAYRACFADGTT
                     LDVHTGADAMAAEVERFAGAREAAGYRRLRDWLGRLYTVQMRRFIDANFDSPLGLLTPD
                     LARLAALGGFGRLDARIARFLTDERLQRIFSFQALYAGVAPSRALAAYAVIAYMDTVAG
                     VYFPRGGLHALPRAMAAAAADAGADLRLGRDVTRLERSGTRVTAVVTDHERIPCDAVVL
                     TPDLPVAHRLLGRRPRRPVALRHAPSAVVLHAGTTRTWPHLAHHTLSFGAAWRRTFDEL
                     TRTGTLMTDPSLLITRPTAHDPTLAPEGRHLHYVLAPCPNTDIGPGAHAWSDLAPRYRD
                     RLLATLERRGLTGIAAAVEEECLVTPADWTAQGHAAGTPFSVAHTFAQTGPFRPRNLVR
                     GTDNAVLAGCGTTPGVGVPTVLVSGKLAAARITGTPARARSARGGSR"
     gene            13051..14046
                     /locus_tag="STPH1_RS33860"
                     /old_locus_tag="STPH1_6715"
     CDS             13051..14046
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607879.1"
                     /locus_tag="STPH1_RS33860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6715"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_164385947.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.2e-117,
                     bitscore: 388.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.9e-65,
                     bitscore: 219.1, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="T1TS (E-value: 0.0012, bitscore: 17.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARELDAAGITDPELRAAYTRCRLLNARHGRTYFLATRLLPADR
                     RPAVHALYGFARRADDIVDDMGAEATPAERAAALTRLDRLLRRALTGGRPSTEPVVLAL
                     ADTAARYAIEPAHFTDFMASMRADLTVTDYATYADLRTYMHGSAAVIGLQMLPVLGTVT
                     ARAPAAPHAAALGVAFQLTNFLRDVGEDLDRGRIYLPADLLAAHGVHRDLLLWSRATGR
                     HDRRVTAALRAAEDLTRGVYREAEPGLAMLDPVARPCIRTAFLLYRNILDTIADGGYAV
                     LHRRAVVPRRRRAAVAADGLVRVLAARLRARRTAVPAPVPCDAVDVKEPR"
     gene            14043..15065
                     /locus_tag="STPH1_RS33865"
                     /old_locus_tag="STPH1_6716"
     CDS             14043..15065
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324141.1"
                     /locus_tag="STPH1_RS33865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6716"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_164385948.1"
                     /transl_table=11
                     /translation="MSTEPRPRRGRLPLRLRRRAIPWERQRPTWREARPALVAAALERA
                     GARPSGNWYVLGASTDVRPARPLSGTVEGVEVVVWRDARGRLVGGPGACPHLGAPLADS
                     PVRCGTLVCHWHGLALDGAPFAGWEPLPVHDDGVLVWARLDTVGEEPPTPEPLVPGRPP
                     RPTALTSVWRGVGTCEPEDVVANRLDPWHGAWFHPYSFVDLTVVEAPGESAHPDGDGDR
                     FLVDVSFRLTGRLVVPVRAEFTAPGPRTVVMRITGGEGTGSVVESHATPLGPGGDGRPR
                     TAVVEAVLATSDRPGFPLARRLAPALRPLMRAAAGRLWRDDLAYAERRAHLRARGQFPG
                     "
     gene            15081..15557
                     /locus_tag="STPH1_RS33870"
                     /old_locus_tag="STPH1_6717"
     CDS             15081..15557
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971750.1"
                     /locus_tag="STPH1_RS33870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6717"
                     /product="MSMEG_6728 family protein"
                     /protein_id="WP_164385949.1"
                     /transl_table=11
                     /translation="MQTFLPHPGFRDSALALDRRRLGKQRVEALQVLRGLTVPGYGWRR
                     HPAVRMWTGYEEALVRYGLDVCRVWREQGHQDSCAASLVAGLAECRPGEPVRDQPALAA
                     AGELPPWLGDEAFHRSHRSALVRKEPEVYAELFPGVPDDLPYVWPASDRERGER"
     gene            complement(15570..16319)
                     /locus_tag="STPH1_RS33875"
                     /old_locus_tag="STPH1_6718"
     CDS             complement(15570..16319)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016328064.1"
                     /locus_tag="STPH1_RS33875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6718"
                     /product="hypothetical protein"
                     /protein_id="WP_164385950.1"
                     /transl_table=11
                     /translation="MRTGKVATAVATASVSVALLAGCGGDSADEDKPFEGQSADDIAAK
                     AVEATRQAKSMHVKGDTRLEDGSTVTIDVSVDQEKNCQGTVGAGGTEADVRHTEATLYL
                     RGDEQYWENALKQQPDAAQKMASKLQDKWVKMPANDATTAGVCDKQGLVAAMDEDESER
                     RGMKRGSTTDVDGEQALQLTKDASGGEKLTLYVATEGEPYILKTTTEGGKSPGSVTFSE
                     YGEKVNPEQPPADETVDMKDLAGRQQT"
     misc_feature    complement(16342..16355)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            16535..17470
                     /locus_tag="STPH1_RS33880"
                     /old_locus_tag="STPH1_6719"
     CDS             16535..17470
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446513.1"
                     /locus_tag="STPH1_RS33880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6719"
                     /product="EamA family transporter"
                     /protein_id="WP_164385951.1"
                     /transl_table=11
                     /translation="MNATTTRGALLAALACLLVGGSFTANSLLGDYPYAGGQFLRYGLA
                     FLLLLPLTGPGATTRLRALGAGRWVRLALLAAVGMVGFNLAVLAAERTAEPAVPGVFVG
                     CAPVVVAVVVPLLEGRRPQRVVLYGALFVALGAFTVQGWGRTDGAGLAFSVCALVGEVG
                     FAVLAVPVLRPLGPRLLSTVVCGVAAAESALAGVLADGGGWLRRPDAVETGALLWQAVV
                     VTVVGFVCWYMGMQRIGAERATLFSGLIPVAAACTAPLVGTGSYGAAQAVGSALVFAGV
                     AVGSGALPVGRRRQSAAGRQRAFERSLEKL"
     gene            complement(17434..18972)
                     /locus_tag="STPH1_RS33885"
                     /old_locus_tag="STPH1_6720"
     CDS             complement(17434..18972)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446557.1"
                     /locus_tag="STPH1_RS33885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6720"
                     /product="MFS transporter"
                     /protein_id="WP_164386603.1"
                     /transl_table=11
                     /translation="MDDAKSDGGSGPRSGAKVPSTVARLPRQVREELTLRLRRTKRAFR
                     EEDVQVVEKPLLKRAVGASALGNCMEWFDFGVYSYLAATIGKVFFPGASPAAQVISSFA
                     TFAAAFVVRPLGGLFFGPLGDRVGRQKVLATTMIMMALGTFSIGLIPSYASIGIAAPVL
                     LLFARMVQGFSTGGEYGGATTFVAEYSPDRRRGFLSSWLDFGTFVGYALGSALVTVLNL
                     ALTDAQMLHWGWRLPFLIAGPLGIIGLYMRLKLEESPAFQQQLDEHEKGLAQESAGSEF
                     RTIVREHWRPLLVCMGLVLLYNVTNYMVTGYLPTYQTETLDRSSGFADVLVLIGMVWIV
                     LLITFLGRLSDHVGRRPLYAVGAASMIVLAIPAFLLLKADGIWAPVLGVLLLSTLLACF
                     AAPSAATLPALFPTAVRYAAMAIGFNFAVAAFGGTTPLVAEALVSITGDELMPAYYLMV
                     AGAIGLVAVRFLPESAQVPLHGSQPMVGSRQEQRELITTSKDLYSFSKDRSKAL"
     gene            complement(19103..20440)
                     /locus_tag="STPH1_RS33890"
                     /old_locus_tag="STPH1_6721"
     CDS             complement(19103..20440)
                     /GO_function="GO:0004806 - triglyceride lipase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971746.1"
                     /locus_tag="STPH1_RS33890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6721"
                     /product="lipase family protein"
                     /protein_id="WP_164385952.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 3.2e-06, bitscore:
                     25.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPRPHLLVAAIAAALALGAQAVPAVAADGAATDPAPTTSRGVEI
                     PAFYTPPSELPGADGTVIRSEPLPLALSLPGIDGPLPGRATRLMYKSTDANGEAVAVTG
                     AYIEPAAKWRGEGPRPLVAVAPGTMGQGDQCAASMALEHPLRLNGQTVSVGYEDLSVYR
                     LLLRGVAVVVTDYVGLGTTDRLHTYVNRVDGAHAVLDAVRAARSLDSSSVTSGSRVGLF
                     GYSQGGGATAAAAELQPSYAPDVELSGTYAGAPPADLTKVTEAIDGGDLAGALGWSLNG
                     FLQTEPALRPIADRYINAAGEEALKDLSTMCVGDALFGYGGESSTDWTKTGQSLGDIIR
                     AEPALQDFLAEQRIGALKPGSPVRVATGVSDDLVPHGQARRLAVDWCDKGGKVTYVPVL
                     LPGVGSGLLNHFGPLLADQGNALSWLTDRLSGEPAGSNCWSMPVQP"
     misc_feature    complement(20571..20588)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.07"
                     /tool="antismash"
     misc_feature    20574..20588
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.52"
                     /tool="antismash"
     gene            complement(20741..22825)
                     /gene="cdtC"
                     /locus_tag="STPH1_RS33895"
                     /old_locus_tag="STPH1_6722"
     CDS             complement(20741..22825)
                     /codon_start=1
                     /gene="cdtC"
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031636.1"
                     /locus_tag="STPH1_RS33895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6722"
                     /product="siderophore ABC transporter permease CdtC"
                     /protein_id="WP_164385953.1"
                     /transl_table=11
                     /translation="MAVTATEPATEPTAARPSTVPSSRSGAAAVTAGIVLLVAVLAVVD
                     LTQGTAAVGPSEVLKALTGQADPDDASVVVASRLPRTTAGLLVGAVLGMAGAVLQAVSR
                     NVLASPDTLAVNAGSYLALGLAAATGVSLPMLASSGVAFVGGLAAAAVVLGLSGLGTGT
                     VRLVLAGTALMLGLNSMTEGLLLLFPEQTEGLYAWNQGSIAQNGFDGVVQMLPIALIGL
                     AGLMLTARRVDALALGDDAARGLGVPVRATRVTVVVLAALLSAAAVTLAGPIGFVGLCA
                     PALVRPLARRFRGFGRSRTVMPAAALTGAALVLGSDVLLRALIADDRAVSVPTGVVTSL
                     VGAVFLVAMALRVRDTAGAGAPDRLRTPGRGVFLTTAAVLVVVLVGLVIAAVLVGDTKL
                     LLGDVVNWAQGRAGRTVSFVLDTRVPRVLAALGAGAALALAGTLVQAVTRNPLAEPNVL
                     GVTGGGALGAVILVTTVPAAGTWGVAGAAFAGSAVTAVLVFGLAARGGFRQNRLVLVGI
                     GVASGTAALISLLIVLTDPFNATKALTWLSGSTYGRTMPDVVPVALTLLVGIGVAVARR
                     TELDLISLDEDTPRLLGLRLARGRLGFLVLSVVLSATAVACAGTIGFVGLVAPHAARAL
                     VGRRHVRVVPVAILLGAILVCAADLIGRTVIAPAQLGAGLMTAVIGTPYFLYLLVRSRR
                     "
     gene            complement(22833..23816)
                     /locus_tag="STPH1_RS33900"
                     /old_locus_tag="STPH1_6723"
     CDS             complement(22833..23816)
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971744.1"
                     /locus_tag="STPH1_RS33900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_6723"
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_164385954.1"
                     /transl_table=11
                     /translation="MRRLLLTAAATTAAALTLAACGTTEPAADKTEKKASEAITLKDGK
                     GTEVKLDGPATKVVATEWNVVESLVSLGVDPVGVADVKGYKTWDSAVPLKNEPKDIGTR
                     GEPSMDTVASLAPDLIVATTDLTPAAVKQLREVAPVIEVTSADGTGQIDQMLENVDLIA
                     KATGTTDKAKSLREGFEAKVTEGKKALADAGMSGQNLAFADGYVTANQVSVRPYTATSL
                     IGEVNEAIGLKNAWTVKGDASYGLGATDVEGLTKLPKDTQFAYIGNDDDPSATPFTGEL
                     AKNSVWKSLPFVKAGDVHRLDDGIWMFGGPGSMEAYIDAVVGALTK"
     misc_feature    complement(23990..24004)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
ORIGIN
        1 cggcgcgccg tcctcccgcg ccccgggcaa caggacgcgc cgcggccggt atccccgagt
       61 cggccgcggc gcctcccccc cccgggggcc gcccagcggc tcccccgctc cggtgggcga
      121 tgggtgtcgg ccgccggacc atttgggtgt cgtccccgat ggtcgcgccg tggcccgccg
      181 tgtgaccgtg taccgacgcc gcgcccccgg gggtccctcg gggccggggg acgtttcggg
      241 gaagctccgt cccgcccgtt cgcgggcgtt gccgcacggt tcggtgcggg tctgcggtgc
      301 gggtctgcgg tgcgggtgtg cggtgcgcac cccgggcgca ggggcggcgg atggtcatgc
      361 cggttcaccg ccgcggacgc gccacggatg cgtgcgctcg tcgtccgggc gtgtggccgg
      421 ccagccggtt tcctcccttt cgcctccggg cggtgtcatg ccacggcgtt ccgggcggtc
      481 cacgaccgag aaggacgacc gacgaaggac gaccgacgaa gcacggcaga ccaaacacga
      541 ccgacgaagc acgaccgaga aggagaatgc gcatccatcc ccgtcaagtg aagccctccc
      601 gaccccgcgt gtggccgaag gcggtgaccc gtgggacacg ctgacaccct gctcgccatg
      661 ggcggtgcct tcgtggccgc cgcgttcttc gcccgtctcg gcgggcggat aggactcccg
      721 acgatccccc tgttcatgct cgcaggcatc ctgctcggtc ctcacacacc gggtttcgtc
      781 ctggtggagg acgcgcacga cttcgagatg ctctccgcgc tcggactggt gctgctgctc
      841 ttctacctgg gtctggagtt ccacctcgac gacctcagga gcggcggcaa acggctgctg
      901 acggccgggg gcgtctatct gctcctcaac gtcggcgccg ggctcggctt cggcctcgtc
      961 ctcgggtggg gcgcccgcga ggcgctggtg ctggcggggg tgctcggcat ctcctcgtcc
     1021 gcgatcgtca ccaagatcct catcgacctg ggccggatcg gccgcccgga gacccggctg
     1081 atcctcggtg tcatcgtcgt cgaggacatc ttcctcgcgc tgtacctggc cgcccttcag
     1141 ccggtcatcg cgggcgcgca cggcgtggcc gacacggtcc ttcaggccgg caaggccttc
     1201 ggcttcctgc tggtgctggc cgccgcggcc cgctacggca cccggctcgt gggccgcctg
     1261 atcgacacgc gggacaacga actgctcgtc atcagcttcc tcggcgccgc ggtgctcgtc
     1321 gccggggtct ccgaactcct cggcgtcgcc gacgcgatcg gcgccttcat ggtcggcctg
     1381 atcctcgccg gcactccctc cgggccgcgg atccgcgaac tggtgcaacc gctgcgcgac
     1441 gccttcgcgg cgatcttctt cttcgccttc gggctcgcca tcgaccccgg tgacctcgcc
     1501 tccgtcgcag gcccggtcgc cgcggcggcg gcactgaccg tggtcatgaa cgtcgtcgcc
     1561 gggctgtgcg tcgcccgggt gtaccactac ggcagcgaac cggccgcgga gatcgcgacc
     1621 accctcgtcg cccgggggga gttcgcgctg atcctggccg ccatggccgc gggcgccgga
     1681 ctggacgcac ggctcgcccc cttcatcgcc ggatacgtgc tcgtcctcgc cgtcctcggt
     1741 cccgtcgtcg cgggacgcgc ccacgtactc gccgccgcgc tgcgggccgc cggccggctg
     1801 ctgcccgggg cgacggcacc ggtcccggtc cccgtaccgg gtgacgggaa cggcgggcgg
     1861 acggaggcgg acagcctgcc ggtgccggcc gaggtgtcct cctcgccggg ttccccgccc
     1921 tcgtccccgg aacgcgccga ggcggagcgg tagagcggga gcagacgtcc gggcgagccg
     1981 cacgggtggc cggtcgtcgc cgtcggcgga acggcgccgc gactcccggt gggacaatct
     2041 gaccacgggg tgtcgtccga cgccgtgggc ggacgcgtcc ggaccggaag gagccgtcag
     2101 catgatcgag tgggtgcccc tgggcagcgg tgccagaccc gtgccccggc cggtctcggc
     2161 tcccctggtg tgggcggggg ccttcggcgg cgccctcctc ctggtcgcgc tcctcaacgg
     2221 caccgtgggc tcggggcgtc ccggcttcgc tctggtcgcg ctctccctgc tggcggccct
     2281 gctcgggctc tgcgcccggt tcacggcggc gccggggacg gccgtcctgt gctggctgtc
     2341 cctcaacggc ttcgccattc cgccggccgg caccctcacg tgggccggcc cgcgggacgc
     2401 gttctggctg gcctgcctgc tcggcgcggc cctcgtcggc acggcgctgg cccgcgtggt
     2461 ccacgcgcgg gccgcctacc gccggctcac cacggcgacg ggcctcgacg cgccggagcc
     2521 gggaaccggt cccggcgacg tctgagccgc ccgggcacgg ggccgtgagg acgtccgagc
     2581 ccccgggcgc agggccgcga cgacgtccga gccgacgacc accggggcgt gggcatggcg
     2641 tagcccggcc cccgacaccg gcggtgcggg aggggcggac cggagacccg gccccggccg
     2701 cccctcccca ccgccgccgg atcaggccgt gtgcagggtc aggccgtagc ggttcaggat
     2761 ctcgttgacc ggctggaacc aggtctcccc gccgccggag cagttgcccc agccgcccga
     2821 ggtgacgccc tgcgcctggt caccactgat gaaggagccg ccggagtcgc cgggctcggc
     2881 gcacacactg gtcttggtca gctggtgcac caccgaaccg tcgctgtagt tgaccgtctc
     2941 gttgtgggcg agcacggtgc cgcagtgcca gtgcgtggtg gagccggagc ggcagatcga
     3001 ggcacccacc ggcgccacgt tcgagccgcg cacgagctgg tcggagaccg tgccccagcc
     3061 cagcacgacc ggcaccgtcc accagccgct gcccacgctg acccacgcgt agtcgttgtc
     3121 ggggaacgac gagccctgga acgtgccgat gtacgagccg tcccagccgc tgacccccgc
     3181 gccggcccgg ccgcagtgcc cggcggtgac gaacccgccg tgcacggaga agccgatgga
     3241 gcagcggacg ttgccggtgt agtacgggtc accgccgacc gtgcccgcgg cgaacgtctg
     3301 cggggccgac ggcaccgagc gcaccgtgac cggtccggcc tcgcgcgccc gctcgaggaa
     3361 gctctggaca tcgttgtcgg cgcgctcgct ctcgaccacg tcgacgacca ccgtgttggc
     3421 gctgtggtcg acgcgccagc tgctgacgcc ggcgggggcg tcgaggcggt cgacgcgtgc
     3481 cttggccgcg tccagctgcc gcgcgctgtg ctcgacggtg cgcacctgcg cgccggtggc
     3541 gcggaccgcc cgcacggtcg agggcgccgc gtccgaggtg agggccacgg tcagttctcc
     3601 ggcgtcgggg tcgaaccagg agccgccgaa ggccgttccg gcggcccggc gtgccacggg
     3661 ctcgaggccg gtggcgtcgc gttcggccgc cagccggtcc tcggcctcgg agcggctgag
     3721 gtcgaagtcc cgctgcatgg cgtcgaggag accggcggag gcaggctgcc ggtcggtgga
     3781 ggcggagggg gaggtggagg aggcgtcggc cgccgaggcc ggcagtgtgc cggccgcggt
     3841 gaggccgccg agcacgagga ggccggccag gccgaggtgc ctgagtctgc tgcgtctcac
     3901 gggagttgcc cttcgtcgtt ccagcaaggt gggggtggaa cagccggcat ggaacaaccg
     3961 cggtttgaga gcgctctcat cgggttgttc cgagcttagc cagcccttgt catcaggtcc
     4021 atgccaatgc acgagctttc cgtgccacct gttccgcgcc gcggcgacct cgccgttcgg
     4081 tccggttggc cggtcgccga ctgggcactc agactccgtc ctcgctgtgg cggccccatg
     4141 gcggcccctg gacgtgggag gtacacgtgg cggttcggca caggctgatc caggcgaccc
     4201 cggaggccgt ctgggacgtc ctcgcggacg gaaacacgta cgtggagtgg gtggtgggcc
     4261 cctcggaggt cacccccagg gccgggcagt ggccgcgggt cggcgcgacg atcgcgtacg
     4321 aggtgcggct cggtccgctg cggctgcaca acgagtcggt ggtcaggcgc tgcgtggagg
     4381 gctccgaact ggagctggag gccaaggcgg gccggctcgg cacggcccgg atcgccgtgg
     4441 aactgcgccc gtggggcgag cagtgcctgg tgatcgtgga cgagcaccca ctgcgcggcc
     4501 ccggcggcct gctgcacaac gtcggcgtcg aggcgctgat ccaggtgcgg caccgcgcca
     4561 tgctcgccag gctcgcgaaa ctgtgcgagt ccgaggccgg cgaccgctgc cgtcccgacc
     4621 cgcccgacgt gctcggtccc gtgggccacc ggccgggaac cggccgtgcc tgacgccccg
     4681 gacgccgtcg acgccgtcgt ggtcggagcc gggcccaacg gcctggtggc ggcgaacctg
     4741 ctggccgacg ccggctggag cgtgacggtc ctggaggagc agcccgagcc gggcggcgcg
     4801 gtgcgccacg acggcgaggt cgcccccggc ttcgtcaacg acctgttcag ttccttctac
     4861 ccgctcgccg ccgcctcccc gatcctcggc ggactgcggc tggaggacca cggactgcgc
     4921 tgggcccacg cgccccatgt actggcgcac cccctgaccg acggcacctg cgccgtcctc
     4981 gaccgagacg tcgccaccac cgccgcctcg ctcgacgcct tcgcacccgg ggacggcgcc
     5041 gcctgggagc ggctgcacgc ggtgtgggac cgctaccggg ccgacatcgt ggacgccctg
     5101 ttcaccccct tcccaccggt gcgcgccggc gccaggctgg ccctgcggct gcgcggcgcg
     5161 ggcgggctga ggctcgcccg caccctggtg ctgccggtgc gccgcatggg cgaggaggag
     5221 ttccggggcg agggcggcaa actgctgctg gccggcaacg ccctgcacgc cgacctcgcg
     5281 cccgaggcgg ccggcagcgg cggcttcggc tggctgatgt cgatgctcgg acagacctac
     5341 ggcttccccg tgcccgtcgg cggctccggc gccctcaccg gggccctggt ccaccggctg
     5401 cgcgcccggg gcggcaccct gcactgcggg cggcgcgtcg aacgggtcct ggtccgcgac
     5461 cggcgcgccg tcggcgtccg caccgccgac ggggagacgg tgaccgcccg ccgcgccgtc
     5521 ctcgcggacg tctccgtccc cgccctctac ggcgggctcg tccctccggc ggacctgccg
     5581 gaccaggtcc tcgccgacct gcggcgcttc cagtgggact tcgccacctt caaagtggac
     5641 tgggcgctgg acggtcccgt gccctggcgg tgcgaggcgg cggcccgggc cggcaccgtg
     5701 cacctcgccg acggcctcga cgagctgacc cggttcgccg cccagatcgc catgcggcag
     5761 gtccccgacc gtcccttctc gctgttcggg cagatgacga ccaccgaccc gacccgctca
     5821 ccgagcggca ccgagtccgc ctgggcctac acccgcgtcc cccacgacat ccgagccgac
     5881 gcgggcgacg agggcatcac cggcagctgg gacacccggg agcgggaact gatggccgac
     5941 cgggtcgaac gccacgtgga acggttcgcc cccggattcc gtgcgctggt ccgggcccgc
     6001 cgagtgctcg ccccgccggc gctccaggcc atggacgcca acctggaggg cggcgccatc
     6061 aacggcggca ccaccgccat gcaccagcaa ctcgtcttcc gccccgtgcc cggcaccggg
     6121 cggccggaga caccggtggc cggtctcttc ctcgcctccg cgggcgccca cccgggaggc
     6181 ggggtgcacg gggcacccgg cgccaacgcc gcgcgcgccg cgctgcgtca gcaccggttc
     6241 gcggggctcg cccgggtgca gcgggccctg acccgacgag accgggcggg cgaccgttgc
     6301 tgaacgccgg tgaccgtccg cacaagcccc cgagccgtcc gacgaagagg gaagggcccc
     6361 cgtgacagac agccccctcc agaaccgcac cgtcgtcgtg accggcgccg cacgcggact
     6421 cggcgccgcc gtggcccgcg cctgcgcccg ccgcggcgcc cggctcgcac tgctcggcct
     6481 cgagaagccg tgcctcgacg ccctggcggc ggacctgccg accccggcac tcgccgtcga
     6541 gaccgacgtc accgacccgg ccgcactggc cgacgcggcc gacgagaccc gcaggcgcct
     6601 gggcaagccg tcggtcgtgg tgtcgaacgc cggagtcgcg cacggcggac cgttcgccac
     6661 gtccgacccc gccgagtggc gccgcgtcgt cgacgtcaac ctgaccggta gcgcccacac
     6721 ggcccgcgcc ttcctgccgg acctgctcga caccgcgggc taccaccttc agatcgcctc
     6781 gctggcctcg ctcggcgccg cacccctgat gagtgcctac tgcgcctcca aggccggcgt
     6841 ggaggccttc acccactcgc tgcgcgccga ggtggcccac cgcggcgtcg ccgtgggcat
     6901 cgcctacctc aactggatcg acaccgacat gatccgcgac gccgaccgct acccggtgct
     6961 gcgcgaactg cgcgcccaca tgccgccccc ggcccgccgc acctttccgc cggaggacgt
     7021 cgccgcccgc ctggtgcgcg ccgtggaacg ccgccgtacc gccgtgtacg tgccgggctg
     7081 gctgcgcctg gtccagctgg ggcgcgtgac cctgccgccc gcggtcgtac ggctgtcccg
     7141 ccacgaactg ccccggatgg aggccgagga ggccctggac cacaccggac cgctgggcgc
     7201 tggcgggctg gccgaccgcg cggcggaccc gcggcagtag ccgccggcgg ggcgcggacg
     7261 ggcctgtgtc agtgcgcccc gaaccgccgg gccagggccc gcagcggcgc cgaccggccc
     7321 cggtcgggca ccgtccacag cgtttcgccc cgcacccccc agcgctccag cagggcgccc
     7381 gcggcgagga acccggaggt ggcggcgcgc tccatcagcg ccaccggcag atccgtacgg
     7441 accaggtccc cggcgaccac gacggccgga tcgggcgtgc gcaccgtggg gcggtcgcgg
     7501 tagcccccga cggtgaacag cgggcagtcc gcccgccatt cgtgccgtgc ggcgaccacg
     7561 cgggcccggc gggtctccgg gtacacccgg tgcaactggt cgacgaggcg cttctcctcg
     7621 acctcgcgga cggccgccga cggcacggcg taggcgtgga gttcgacgac gcagcccccg
     7681 gtgcgcgccg cccagcgggc cgcctcgccc tcccagtggg acagcacgct gacgttgtcc
     7741 agcgagccgt aaccgctggt gccgaggaac ccgggccggc cgggcgcgac cgggcggtcc
     7801 agccacagcc gggagaccag gaacggcgga gcgttccgca gccgcgccac ccgcgtccgc
     7861 cagccggcgt cccccaggtg cggcgagcgg gacaccacgt cccgcagccc accgacgtcc
     7921 atggcgagca ccacggcgtc gtacggccgg gccccggcgg cgtcgaccac gagccgcccg
     7981 ccggacgggc cgggccggac cgcctcgacg gcggtgtccg tgcgcacctc gaccccgtgc
     8041 cgcgccagat gcccggcgag gggatcccac agcgcctgcg ggaacggctc acgtggtacg
     8101 tcgaacagca acccctcgct ggagccgagg aagtagatgt ggaacatcag cgccatctcc
     8161 gcggccgaca gctcgcgcgg gtcggcgaag aagctgcggg agaacacctc gaaggccagg
     8221 tgccgggcgg ccgggggaaa acgcagggag tcgaggaagt cgtgggcgct gaggtcgtcc
     8281 aggcgctcgt ggacgcggcg ggtgcggacg tcgaggagcg gcagcgcggc cgagggccgc
     8341 agggacgtca ggtcccgcag cccgaaactg ggactcaggg cgacgaaggc gagggcgctg
     8401 aacgggggag tgcgcggaat ccggcggaag ccgtcgtgca gcccgctgct gtgccgcagg
     8461 gggtagtcgg gcaggccggt cagcatggcc aggccgggat cgccacggcg caacaggccc
     8521 cgcaggttgt agtactggcg gaagaaggcg tggaaccccc ggctcatcgt ggcgggcgtg
     8581 ccgtccggca gggcgaacgt ccggcccgag acccggccgc cgagcacggg ctcgcgctcg
     8641 tacagcacga cgcgcacccc gcgttccgcc aggacggtgg ccgccgccag gcccgcgatg
     8701 ccaccgccga tcaccgccac cgacggcgcg ccgccctcga cgcgctcccg cccgggcccg
     8761 ggacacagca tccgcgcccg ccggtcccgc ccgggcggcc gcaccgcacg gccccggccg
     8821 ccggcacccc gccggatcac cgggcccctc cgccgcgcgc ggggcggaca cgcgtgccgc
     8881 cggacccggt gccggggacc cggacggcgt cgtgacgcgg gccggtggtc ggcgcgtccc
     8941 cggttccggc gccgtcggtc cgggaaccgg gggccccggc tccgcgagtc cggacggcgt
     9001 cgtggtgcgc gtggccggtt cgcgcgtcgg cggttccggc gccgtcggcc ggagtcccgg
     9061 aggccggtgc gacgtcgttc cccgcgccgc ccgtgcggac accgccgctc ccggtgccgt
     9121 cggtccgggt gccgctgccg ccggtccgca cgctgcccgt ctcgcgcgcc gtaccgcccg
     9181 gttccccgtg ggcgcgacgg ccgacgaagg tgtgggtgat acccgtctgc cagccgggca
     9241 gcggcagcac acggaccccc gcgaacccgg cccgccccag ccgcgcgccg aacgccgggg
     9301 ccgtgtcgaa cgccgcgacg ctgcgccaca ggtgccggta cagctcccgg tcgcccgtcg
     9361 ccgtgcccag cggcaggatg acggcgcggc acaccgcgtc ccacaccagc cggttgccgc
     9421 gccgcccgcc gagcgcgtac tcgtgcaccg ccagccggcc accggggacc agcatccgcc
     9481 gcaccgaccg caggacggcg tcggggtcgg acacgttgcg gaacaggtag gcggcgaaca
     9541 ccgcgtcgaa ggggccgcgg acctcggccc ggtccaagcc ctcccggtcc aagtcctccc
     9601 ggtccaagtc ctccagatcc aggtcctcca gatccaggtc ctcggccgcc gcgtgcacaa
     9661 agcgcacccg cgagggccac cgcttggccc gggcccgctc cagcatgccg gccgaggcgt
     9721 ccaccccgac gatctcggcc gccgggaagg ccgcggccag ggcggcggtc gaggcccccg
     9781 tgccgcagcc caggtccagc acccggcccc cggcaccgcc gtccgcgagg cccagccggc
     9841 gggccgagcg gcgcaactgg gagtggtagc cggggttgag cgcgacgagg cggtcgtagc
     9901 ggccggcccc gcggtcgaag gcggtggtca gcgcggcgtc gcgcagcaag ggcatcgggg
     9961 gctcctggcg ggtcgagggt cgagggtcgg cggacggcgt tcagcggacg ggcaggtgac
    10021 ggcgcggcag ccacggcagt tcggccgccg tgcgcagcat cggcaggacg gggacgcgca
    10081 ccccgaccgc gaggtcctcg gacagccgcg acccgccgtc gaggaaccgc agcagccgcg
    10141 cggcgggtac gcggtcgaac agccggaaga agaggtcggg cccgtcgacc cggccggtgt
    10201 ccagcgcgcg cagcagcacc gcgtccatcc accgggcccg cgccggatgc gggggcggcg
    10261 gcaccgggcg gcggcccgcg cgcaccgcac gggcgacggc ctcggactgc cgctgcacgg
    10321 cggcgaacgt gtagccggtg gacgcccgcg tcgccccgcc cgcgacgccg atccggaaga
    10381 cccggtcgca gcccccggcc cgccgctcga agatggcgtc ggtcatgggg atgaccccct
    10441 gctcggtcga caggacctcc atggcgccgg tgcgcagcac acggcgcgtg tagtcctcca
    10501 gcgcaccgtc gtacgcctcg gtcgtcaggg gcgccgggcc gaactcggtg tactcgacca
    10561 gcgcggtgtg ccgtccggtc ggcagcacgt agccgaacga caggccccgg cgcggctgcg
    10621 cggtgcggaa gtccatcagg tcgaccaccc ccgggtcgaa ggccggccgc tcggtgcgca
    10681 cgaaccagcc gcggaagtgc tggagcagcc gggtgcgggc ggccggcagc cggtccggcg
    10741 gacgggagtc gaagacccag cgggcgcgca ggccgaccgg cgcgcccgag gcgtccgtgg
    10801 ccgccacccg cacggtggcg tccggcagga cggtcaccgc gccgacggtg gcctcgacgc
    10861 gccgcagccc cggacggtcc ttcaggtccc gctccaccag cgcctcgaag tcgtccgagc
    10921 ggatcatctt gtagcgggcc ggcgcgatgt gccgccggac gaccgtgccg tcccggccgt
    10981 gcacccgcag ccactcccac gtcgccgtcg ccgcccggtc gaagcggccg cacccggcct
    11041 cccagaagca ccaggtgcga cgcgggggcc gcagcggtcc gggcggcgga tcgaccagga
    11101 cgacggagga cgccgcaccg ggcggcgccg cggccgggag ccggtggacc agggacagcc
    11161 cggccgcccc cgcaccgacg accacgatct ccgcgtcgag cacgcccgcc tccttcgcgt
    11221 cggtgtccac ccgccggccc gcccaggtcc ggtccgcccg gtccggtcct gccgcggtcc
    11281 ggtccggcgg agtattccgc ccgccgcggt ccgcggaacg tccggcgcgc tggacggcgc
    11341 gacacgggta cccgcccggg gacgcgatac cgccgggcgg gtgactgccg gacggcaacc
    11401 ggcccgtggg gcgtcgcccc gggggcgaag ggggaaggct gacgccgacc cgtacgagag
    11461 gacccgcaat gcgccgcagc acggccgacc acggcgacca ccggccgcac ccaccgctcg
    11521 cgggccgggg cgcgcgatga cgcggacggt gcccggccgc accgaccacg tcgtggtcgt
    11581 cggggccggt ctcgccgggc tggccgccac cctgcacctg ctgggcgccg gccgccgggt
    11641 gacggtcgtg gaacgcgacc cgctgcccgg cggccgggcc ggacggcgcg cactcggcgg
    11701 ctaccacctc gacaccggcc cgaccgtgct gaccatgccc gacctcgccg acgaggcctt
    11761 cgcggccgtc ggcgaacggc tgcgcgaccg cgtcgaactc ctgcccctgc accccgccta
    11821 ccgcgcctgc ttcgccgacg gcaccaccct cgacgtccac accggcgccg acgcgatggc
    11881 cgccgaggtc gaacggttcg ccggcgcccg ggaggcggcc gggtaccggc ggctgcgcga
    11941 ctggctcggg cggctgtaca cggtgcagat gcgccggttc atcgacgcca acttcgactc
    12001 gccgctcggc ctgctcaccc ccgacctggc ccggctcgcc gccctcggcg gattcggccg
    12061 gctggacgcc cgtatcgcac ggttcctgac cgacgagcgg ctccagcgga tcttctcctt
    12121 ccaggccctc tacgccggtg tcgcaccctc ccgggcgctg gccgcctacg ccgtcatcgc
    12181 ctacatggac accgtcgccg gcgtgtactt cccgcgcggc ggcctgcacg ccctgccccg
    12241 ggccatggcc gcggccgccg ccgacgccgg ggccgacctg cgcctcggac gggacgtcac
    12301 ccgcctggaa cggtccggca cccgcgtcac ggcggtcgtc accgaccacg agcgcatccc
    12361 gtgcgacgcc gtcgtcctca cccccgacct gcccgtcgcc caccggctcc tcggccgccg
    12421 cccgcgccgc cccgtcgccc tgcgccacgc gccctcggcc gtggtcctgc acgccggcac
    12481 cacccgcacc tggccgcacc tggcccacca cacgctctcc ttcggcgccg cgtggcggcg
    12541 gaccttcgac gaactcacca ggaccggcac cctcatgacc gacccgtccc tgctgatcac
    12601 ccggcccacc gcccacgacc ccaccctcgc ccccgagggc cgccacctcc actacgtcct
    12661 cgcgccctgc cccaacaccg acatcggccc cggcgcccac gcctggagcg acctcgcgcc
    12721 ccgctaccgc gaccggctgc tcgccaccct ggaacgccgg ggactgaccg gcatcgccgc
    12781 cgccgtggag gaggagtgcc tggtgacacc cgccgactgg accgcgcagg ggcacgccgc
    12841 gggcaccccg ttctccgtcg cccacacctt cgcccagacc gggcccttcc ggccccgcaa
    12901 cctcgtacgc ggcaccgaca acgcggtcct cgcgggctgc gggaccaccc cgggcgtcgg
    12961 cgtgccgacc gtactcgtct ccgggaagct ggccgccgcc cggatcaccg gcacaccggc
    13021 ccgcgcccgg tcggcgaggg gcgggtcgcg atgaccgccc gcgaactcga cgccgccggc
    13081 atcaccgacc cggaactgcg ggccgcctac acccggtgcc ggctcctcaa cgcccgccac
    13141 ggacgcacct acttcctggc cacccgcctc ctgcccgccg accgcaggcc cgccgtgcac
    13201 gccctgtacg ggttcgcgcg ccgggcggac gacatcgtcg acgacatggg ggccgaggcc
    13261 acgcccgccg aacgcgccgc cgccctcacc cgcctcgacc ggctgctgcg gcgggcactc
    13321 accggcggac ggccgagcac cgaaccggtg gtgctcgcgc tggccgacac cgccgcccgg
    13381 tacgccatcg aaccggcgca cttcaccgac ttcatggcct cgatgcgcgc cgacctcacg
    13441 gtcaccgact acgccaccta cgccgacctg cgcacctaca tgcacggctc ggccgccgtc
    13501 atcggcctcc agatgctccc cgtgctgggc accgtgaccg cccgcgcccc ggccgccccg
    13561 cacgccgccg cgctgggcgt cgccttccag ctgaccaact tcctgcggga cgtcggcgag
    13621 gacctggacc gcggccggat ctacctgccc gccgacctgc tcgccgcgca cggcgtccac
    13681 cgggacctgc tgctctggag cagggccacc ggccgccacg accggcgcgt caccgccgcg
    13741 ctgcgggccg ccgaggacct cacccggggt gtctaccgcg aggccgagcc cggactcgcc
    13801 atgctcgacc ccgtcgcgcg gccctgcatc cgtaccgcgt tcctgctcta ccggaacatc
    13861 ctcgacacca tcgcggacgg cgggtacgcg gtactgcacc ggcgcgcggt ggtgccccgc
    13921 cggcggcgcg cggccgtcgc ggccgacggg ctcgtacgcg ttctcgccgc ccggctccgg
    13981 gcgcgccgca ccgccgtgcc cgcaccggtg ccgtgcgacg ccgtggacgt gaaggagccc
    14041 cgatgagtac cgaaccccgc ccccgccggg gacgcctgcc cctgcggctg cggcgccgcg
    14101 cgatcccctg ggagcggcag cggccgacgt ggcgcgaggc ccgccccgcc ctcgtcgccg
    14161 ccgcactcga acgcgccggg gcccgcccct cgggcaactg gtacgtcctc ggcgcgagca
    14221 ccgacgtacg tcccgcgcgc ccgctgtccg gcaccgtcga gggcgtcgag gtcgtcgtct
    14281 ggcgggacgc gcgcgggcgg ctggtgggcg gccccggcgc ctgcccccac ctcggcgccc
    14341 cgctggccga cagccccgtg cggtgcggca cgctcgtgtg ccactggcac ggactcgccc
    14401 tggacggcgc cccgttcgcc gggtgggaac ccctgccggt ccacgacgac ggcgtactgg
    14461 tgtgggcacg gctggacacg gtgggggagg agccacccac cccggagccc ctcgtgcccg
    14521 gccggccgcc ccggccgacg gccctgacgt cggtgtggcg cggcgtgggg acctgcgagc
    14581 ccgaggacgt ggtcgccaac cggctcgacc cgtggcacgg agcctggttc cacccgtact
    14641 ccttcgtgga cctcaccgtc gtcgaggcgc ccggggagag cgcgcacccc gacggggacg
    14701 gcgaccgctt cctcgtggac gtgtccttcc ggctgaccgg ccgtctggtc gtccccgtac
    14761 gcgccgagtt caccgcgccc gggccccgca ccgtcgtcat gcgcatcacc gggggcgagg
    14821 gcaccggatc cgtcgtggag agccacgcca cgccgctcgg cccgggcggc gacggccggc
    14881 cgcgcaccgc ggtggtcgag gcggtgctcg ccacctcgga ccggcccggc ttccccctcg
    14941 cccggcgcct ggcaccggcc ctgcggccgc tgatgcgggc cgccgcgggc cgcctgtggc
    15001 gcgacgacct cgcctacgcc gaacgccgcg cacacctgcg cgcccgcggc cagttccccg
    15061 gctgaacgga gcgccaccgc atgcagacct tccttcccca cccgggcttc cgggactccg
    15121 cactggccct ggaccggcgc cgcctcggca aacagcgcgt ggaggcgctc caggtgctgc
    15181 gcggactcac cgtccccggc tacggctggc gcagacaccc cgccgtgcgg atgtggacgg
    15241 gctacgagga ggcgctcgtc cgctacggtc tcgacgtctg ccgggtctgg cgcgagcagg
    15301 gccaccagga cagctgcgcg gcctcactcg tcgcggggct cgccgagtgc cgccccggtg
    15361 aaccggtgcg cgaccagccg gcactggcag ccgccgggga actgccgccc tggctcggcg
    15421 acgaggcctt ccaccgcagc caccgctcgg ccctggtgcg caaggagccg gaggtgtacg
    15481 ccgaactgtt cccgggagtc ccggacgacc tgccctatgt gtggccggct tcggaccggg
    15541 agcgcggaga gcggtgacgc ccgggacggt caggtctgct gcctgcccgc gaggtccttc
    15601 atgtcgaccg tctcgtcggc cggcggctgc tcggggttca ccttctcgcc gtactcgctg
    15661 aacgtgacgc tgccggggct cttgccgccc tcggtcgtgg tcttcaggat gtacggctcg
    15721 ccctccgtcg cgacgtagag ggtgagcttc tcgccgccgg aggcgtcctt ggtcagctgc
    15781 agggcctgct cgccgtccac gtccgtcgtc gagccgcgct tcatgccccg gcgctcggac
    15841 tcgtcctcgt ccatggcggc gacgagcccc tgcttgtcgc agaccccggc ggtcgtggcg
    15901 tcgttcgccg gcatcttcac ccacttgtct tggagcttgg acgccatctt ctgtgccgcg
    15961 tcgggctgct gcttcagggc gttctcccag tactgctcgt cgccccgcag gtagagagtc
    16021 gcctcggtgt gccgcacgtc cgcctcggtc ccgccggcgc cgacggtgcc ctggcagttc
    16081 ttctcctggt cgaccgaaac gtcgatggtg acggtgctgc cgtcctccaa ccgggtgtcg
    16141 cccttcacgt gcatggactt cgcctgccgg gtcgcctcga cggccttcgc ggcgatgtcg
    16201 tcggcgctct gcccctcgaa cggcttgtcc tcgtcagccg aatcgccgcc acagccggcc
    16261 aggagggcga cggagacgct cgcggtcgcc acggcggttg ccacctttcc ggtacgcact
    16321 ggcagttcct tcccatgtct gttcatcacc gtcaaatcct ctgctgtccc gatgtgttgg
    16381 catcggggcc ttccgactac cccggatccc cgtggcatgc acacgaggga gaagcggtga
    16441 cggtcgtgtg agcggccctc gtcccgattg gtccccgaca gcgcacccga agtggacccc
    16501 gtggcgggcc gccgcgctcc ctagcgtcgt ggccatgaac gccaccacca cgcgcggggc
    16561 cctgctcgcc gcgctcgcct gcctcctcgt cggaggatcc ttcaccgcca acagcctgct
    16621 cggcgactac ccgtacgcgg gcggccagtt cctgcgctac ggcctggcct tcctgctgct
    16681 cctgccgctc accggtccgg gcgcgacgac ccggctgcgg gcgctcggcg ccggccggtg
    16741 ggtgcgcctc gcgctgctcg cggccgtggg catggtcggc ttcaacctcg ccgtgctcgc
    16801 cgcggagcgc acggccgagc ccgcggtgcc cggcgtcttc gtgggctgcg cgcccgtggt
    16861 cgtcgccgtc gtcgtccccc tcctggaggg gcgccggccg caacgggtcg tcctgtacgg
    16921 ggcgttgttc gtggccctgg gggccttcac ggtccagggc tggggccgta ccgacggcgc
    16981 gggcctcgcc ttctcggtgt gcgcgctggt cggcgaggtc gggttcgccg tgctggcggt
    17041 gcccgtactg cggcccctcg gcccgcggct gctgtccacc gtggtgtgcg gtgtcgcggc
    17101 ggccgagtcg gctctggcgg gcgtcctggc cgacggcggc gggtggctgc gccggccgga
    17161 cgcggtggag acgggcgcgc tgctgtggca ggcggtggtg gtcaccgtcg tcgggttcgt
    17221 gtgctggtac atgggcatgc agcggatcgg ggccgagcgt gccaccctgt tctccgggct
    17281 gatcccggtc gccgcggcct gcacggcccc cctcgtcggc acgggttcct acggcgcggc
    17341 ccaggccgtg ggcagcgccc tggtcttcgc cggggtcgcc gtggggtcgg gcgcgctgcc
    17401 cgtcgggcgc cggcgacaat ccgcggcggg gcgtcagagg gccttcgagc ggtccttgga
    17461 gaagctgtag aggtccttcg aggtcgtgat cagctcacgc tgttcctgcc gggagcccac
    17521 catgggctgc gagccgtgca gcggcacctg ggcgctctcg ggcaggaacc tcacggccac
    17581 caggccgatg gcgcccgcga ccatcaggta gtaggcgggc atcagctcgt cgccggtgat
    17641 gctcaccagg gcctcggcga cgagcggcgt ggtgccgccg aaggccgcga cggcgaagtt
    17701 gaagccgatg gccatcgcgg cgtagcgcac ggcggtcggg aacagcgcgg gcagggtggc
    17761 cgcgctgggc gcggcgaagc aggccagcag ggtggacagc agcagcaccc ccaggaccgg
    17821 cgcccagatg ccgtccgcct tcagcagcag gaacgccggg atcgcgagga cgatcatcga
    17881 cgcggcaccg acggcgtaca gcgggcggcg gccgacgtgg tcgctgagcc gtccgaggaa
    17941 ggtgatcaac agcacgatcc acaccatgcc gatcagcacc agcacgtccg cgaagccgct
    18001 ggagcggtcc agggtctccg tctggtaggt cggcagatag ccggtgacca tgtagttggt
    18061 gacgttgtag agcagcacca ggcccatgca gacgagcagc gggcgccagt gctcgcgcac
    18121 gatcgtcctg aactcgctgc ccgccgactc ctgggccagg cccttctcgt gctcgtcgag
    18181 ctgctgctgg aaggcggggg actcctccag cttgagccgc atgtacaggc cgatgatgcc
    18241 gagcggcccg gcgatcagga acggcagccg ccagccccag tgcagcatct gggcgtcggt
    18301 cagcgccagg ttcagaacgg tgaccagcgc cgagcccagc gcgtagccga cgaaggtgcc
    18361 gaagtcgagc cagctggaga ggaagccgcg ccgccggtcg ggtgagtact cggcgacgaa
    18421 ggtggtggcg ccgccgtact cgccgccggt ggagaagccc tggaccatcc gggcgaacag
    18481 cagcaggacc ggggcggcga tgccgatgct ggcatagctg gggatgaggc cgatggagaa
    18541 ggtgccgagc gccatcatga tcatggtggt ggcgagtacc ttctgccggc cgacgcggtc
    18601 cccgagcggg ccgaagaaca ggccgccgag cgggcgtacg acgaaggccg cggcgaaggt
    18661 ggcgaaggag gagatgacct gggcggcggg tgaggcgccg gggaagaaca ccttgccgat
    18721 ggtggcggcc agatagctgt agacgccgaa gtcgaaccac tccatgcagt tgccgagcgc
    18781 cgaggccccg accgcgcgct tgagcagggg cttctcgacg acctggacgt cctcctcgcg
    18841 aaacgcccgc ttggtgcggc gcagccggag ggtcagttcc tcgcgcacct gccgcggcag
    18901 gcgcgcgacc gtactcggca ccttcgcccc gctccggggt ccggacccgc cgtcggactt
    18961 cgcgtcgtcc acgccgctgc cttcctgtcg ttccgccacg gttcgcctga gcgaattctg
    19021 tgccgcagtt cggaaggggc gcatgccggc gccgctgccc ggggcggcgc ggatgccccg
    19081 ggcagcggcg gtgcggtacg gctcagggct gtaccggcat gctccagcag ttggagccgg
    19141 ccggctcgcc ggacagccgg tcggtgagcc aggagagggc gttgccctga tcggcgagca
    19201 gcgggccgaa gtggttgagc agtccgctgc ccacgcccgg cagcagcacg gggacgtagg
    19261 tgaccttgcc gcccttgtcg caccagtcga cggccagccg gcgggcctgg ccgtggggga
    19321 ccaggtcgtc gctgacgccc gtcgccacgc ggacggggct gccgggcttc agcgcgccga
    19381 tgcgctgctc ggcgaggaag tcctggagcg ccggctcggc ccggatgatg tcgccgaggg
    19441 actgcccggt cttcgtccag tccgtgctgc tctcgccgcc gtaaccgaag agcgcgtcgc
    19501 ccacgcacat ggtcgacagg tccttcagcg cctcctcgcc cgcggcgttg atgtaccggt
    19561 cggcgatggg ccgcagggcg ggctcggtct gaaggaagcc gttgagcgac cagcccagcg
    19621 cgcccgccag gtcgccgccg tcgatagcct ccgtcacctt ggtcaggtcg gcgggcggcg
    19681 caccggcgta ggtgccggac agctcgacgt ccggggcgta ggagggctgc aactcggccg
    19741 cggccgccgt cgcacccccg ccctggctgt acccgaacag gccgacccgg gagccggagg
    19801 tgacggacga cgagtcgagg gagcgcgcgg cgcgcacggc gtccagcacg gcgtgcgccc
    19861 cgtcgacgcg gttgacgtag gtgtgcagcc ggtcggtggt gcccaggccc acgtagtcgg
    19921 tgacgacgac ggcgacgccg cgcagcagca gccggtagac cgacaggtcc tcgtaaccga
    19981 cggagaccgt ctgcccgttg agccgcagcg ggtgctccag ggccatcgag gcggcgcact
    20041 ggtcgccctg ccccatggtg ccgggcgcga cggcgaccag ggggcgcggt ccctcgccgc
    20101 gccacttcgc ggccggttcg atgtaggcgc cggtgacggc gacggcctcg ccgttcgcgt
    20161 cggtggactt gtacatcagc cgggtcgccc ggccggggag cgggccgtcg atcccgggca
    20221 ggctcagcgc cagggggagc ggctcgctgc ggatcaccgt cccgtcggcg cccgggagtt
    20281 cggacggcgg ggtgtagaag gcgggtatct cgacgccgcg cgacgtcgtg ggggccgggt
    20341 cggtggccgc gccgtcggcc gcgaccgccg ggacggcctg cgcaccgagg gcgagcgcgg
    20401 cggcgatcgc cgccacgagc aggtggggac gtgggggcat ggcgaacctc ctggggaaag
    20461 gccggatccg gtcgtccgcg gccccgtggg gccggggccg tggtcgcgct gctcctgtgg
    20521 ggttacggga ccgtaaccgg acaggggtta ccaggggtag cacctgactc attacggttc
    20581 agtaacttga cgccatgtct aacaagagcc cggccgggtt gtcccccggg gcccgcggtc
    20641 ggctccgtgc ggaacgcgcc gacccgggag cgggccggcc gcaccgggat caggtgcccg
    20701 ggccacccgc tcccgggcgt cgaggtcgtc ccacggtcgc ctagcgacgg ctccgtacca
    20761 gcaggtacag gaagtacggc gtgccgatca ccgctgtcat gagccccgcg ccgagctggg
    20821 ccggggcgat caccgtgcgg ccgatgaggt cggcggcgca gacgaggatg gcgcccagca
    20881 ggatcgccac cggcacgacc cgcacgtggc gccggcccac gagggcgcgt gccgcgtgcg
    20941 gagccaccag cccgacgaac ccgatggtgc ccgcgcaggc caccgcggtc gcgctgagga
    21001 cgacgctcag caccaggaac ccgaggcggc cccgggccag ccgcaggccg agcaggcgcg
    21061 gggtgtcctc gtccagcgag atcaggtcca gctcggtgcg ccgggcgacc gcgacaccga
    21121 tgccgacgag cagcgtcagc gcgaccggca cgacgtcggg catggtccgt ccgtaggtcg
    21181 aacccgacag ccaggtcagc gccttggtgg cgttgaacgg gtcggtgagc acgatcagca
    21241 gactgatcag cgccgccgtc ccggaggcca cgccgatgcc gacgaggacc agccggttct
    21301 gccggaagcc gccccgggcg gcgagcccga agacgaggac ggcggtgacg gcggaccccg
    21361 cgaacgcggc ccccgccacg ccccacgtcc cggcggccgg gaccgtggtc accaggatca
    21421 ccgcacccag cgcgccgcca ccggtcacac cgaggacgtt cggttcggcg agcggattgc
    21481 gggtgacggc ctgcacgagc gtgccggcca gggcgagcgc cgcgcccgcg cccagcgcgg
    21541 cgagcacccg cggcacccgc gtgtccagga cgaaggagac ggtccgcccg gcccgtccct
    21601 gggcccagtt gacgacgtca ccgagcagca gcttggtgtc gcccaccagt acggcggcga
    21661 tcacgagccc caccaggacc acgaccagga cggcggccgt cgtcaggaac accccgcggc
    21721 cgggggtgcg cagccggtcc ggtgccccgg cgccggcggt gtcccgcacc cgcagcgcca
    21781 tggcgaccag gaacacggcg ccgaccaggc tggtgaccac acccgtgggc acggacaccg
    21841 cgcggtcgtc cgcgatcagg gcccgcagca gcacgtccga accgagcacc agggccgcgc
    21901 cggtgagcgc cgccgcgggc atcaccgtac gggagcggcc gaagccgcgg aaccggcggg
    21961 cgagcggacg caccagggcg ggcgcgcaca ggccgacgaa gccgatcggg ccggcgagcg
    22021 tgacggcggc ggcggacagc agtgccgcca gcacgacgac cgtgacccgg gtggcccgca
    22081 ccgggacgcc gagaccgcgc gcggcgtcgt cgccgagggc cagcgcgtcc acccggcggg
    22141 ccgtcagcat cagcccggcc aggccgatca gggcgatcgg cagcatctgc acgacgccgt
    22201 cgaagccgtt ctgggcgatg ctgccctggt tccacgcgta caggccctcc gtctgctccg
    22261 ggaagagcag cagcagtccc tccgtcatgg agttgaggcc cagcatcagc gcggtgcccg
    22321 ccagcaccag ccggacggtc cccgtgccga ggccggacag accgagcacg acggccgccg
    22381 ccgcgagtcc gcccacgaag gcgacaccgg acgaggcgag catcggcagc gagacacccg
    22441 tggcggcggc cagccccagc gccaggtagg aaccggcgtt cacggcgagg gtgtcggggg
    22501 aggcgagcac gttgcggctg accgcctgga gcacggcgcc ggccatgccc aggaccgcgc
    22561 cgaccaggag ccccgcggtc gtgcggggca gccgggaggc gacgacgacg gacgcgtcgt
    22621 ccgggtcggc ctgcccggtc agggccttga ggacctcgga cggaccgacg gcggcggtgc
    22681 cctgggtgag gtcgacgacg gcgaggacgg cgaccagcag gacgatcccg gccgtcaccg
    22741 cggccgcgcc cgaccgggac gacgggaccg tcgacggacg ggccgcggtg ggctcggtgg
    22801 cgggttcggt tgcggtgacg gccatgaccc cgctacttcg tcagggcgcc gacgacggcg
    22861 tcgatgtacg cctccatcga cccgggaccg ccgaacatcc agatgccgtc gtcgagccgg
    22921 tgcacgtcgc ccgccttcac gaacggcagg gacttccaga ccgagttctt cgccagctca
    22981 ccggtgaacg gggtggcgct cgggtcgtcg tcgttgccga tgtaggcgaa ctgggtgtcc
    23041 ttgggcagct tggtcaggcc ctcgacgtcg gtggcgccga gaccgtagga cgcgtcgccc
    23101 ttgaccgtcc aggcgttctt cagaccgatg gcctcgttga cctcgccgat gagcgaggtg
    23161 gcggtgtagg ggcggaccga gacctggttg gcggtgacgt agccgtcggc gaaggcgagg
    23221 ttctggccgg acatcccggc gtcggccagg gccttcttgc cctcggtgac cttcgcctcg
    23281 aagccctcgc gcagcgactt cgccttgtcc gtggtgccgg tggccttggc gatgaggtcg
    23341 acgttctcca gcatctggtc gatctgaccg gtgccgtcgg cggaggtcac ctcgatcacc
    23401 ggggcgacct cgcgcagctg cttcacggcg gccggggtga ggtccgtggt ggcgacgatg
    23461 aggtcggggg cgagggaggc gacggtgtcc atgctgggct cgccgcgggt gccgatgtcc
    23521 ttgggctcgt tcttcagcgg aacggcgctg tcccaggtct tgtatccctt gacgtccgcg
    23581 acgccgaccg ggtcgacgcc gagcgagacg aggctctcga cgacgttcca ctcggtggcg
    23641 acgaccttgg tggccggccc gtcgagcttc acctcggtgc ccttgccgtc cttgagcgtg
    23701 atcgcctcgg aggccttctt ctccgtcttg tcggcggcgg gttcggtggt gccgcaggcg
    23761 gcgagggtca gcgccgcggc ggtagtggcg gccgcggtga gcaggaggcg tctcatgagg
    23821 tggtgccgag cctttcgagg gttcgtatgt ggtggcggcc gaccgggcgc gtgcgcagcc
    23881 ggccggtcgt ggggtcggtg tcgacgtcga tccggatgcc gtacacggcg gtcaggcgct
    23941 ccggggtcag tacgtcctcg ggcgggccgt cggcgacgat ccggcccgct tcgaggaggg
    24001 tgatccggtc ggcgacggcg gccgcctggt cgaggtcgtg caggac
//
