LOCUS       NZ_WHZR01000001        21086 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. OM5714 A912_AS4_SC1_R2, whole genome shotgun
            sequence.
ACCESSION   NZ_WHZR01000001
VERSION     NZ_WHZR01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. OM5714
  ORGANISM  Streptomyces sp. OM5714
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915160)
  AUTHORS   Samborskyy,M.
  TITLE     Whole Genome Sequence of the phthoxazolin producer Streptomyces sp.
            OM5714
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915160)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2019) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: OCT-2017
            Assembly Method                   :: Newbler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 102.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010993835.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:48:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,730
            Genes (coding)                    :: 7,557
            CDSs (with protein)               :: 7,557
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 7, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 7, 5 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 58 of 173
            Pseudo Genes (incomplete)         :: 139 of 173
            Pseudo Genes (internal stop)      :: 18 of 173
            Pseudo Genes (multiple problems)  :: 36 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2708475
            Orig. end                         :: 2729561
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WHZR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(103..118)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.16"
                     /tool="antismash"
     gene            251..1015
                     /locus_tag="STPH1_RS11545"
                     /old_locus_tag="STPH1_2308"
     CDS             251..1015
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="STPH1_RS11545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2308"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003973740.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTRTQTPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SQDRTGQPVEWVRSVYRGDRYKFVARLKRPQD"
     misc_feature    1090..1104
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(1110..1122)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            1175..1432
                     /locus_tag="STPH1_RS11550"
                     /old_locus_tag="STPH1_2309"
     CDS             1175..1432
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973741.1"
                     /locus_tag="STPH1_RS11550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2309"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_164383283.1"
                     /transl_table=11
                     /translation="MSEDTEVSREPVVTPVRVVIGFCLVAPFVAMLWVGSYAKTDPDFI
                     GIPFFYWYQMAWVLISTLLTVTAYKLWQRDQRGRREGGAK"
     gene            1429..3039
                     /locus_tag="STPH1_RS11555"
                     /old_locus_tag="STPH1_2310"
     CDS             1429..3039
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444565.1"
                     /locus_tag="STPH1_RS11555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2310"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_164383284.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFIFFFVLVTAMGFLAARWRKAENEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFASASDKFTESGKGGVVPDSGGQWTYATLALGSALALFMYPHSITATLSSRSRNV
                     IRRNTTILPLYSLMLGLLALLGFMAIAAGVKVENGQLAIPQLFENMFPDWFAGVAFAAI
                     GIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPQQETKVSKLVSLLVKVGALIFVLGM
                     DKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPT
                     QKHFGGSSDEIPGIGEIGYIGLTAFVLNVLVTVVLTFVLRAVKAPDGVDETQPSDYTAD
                     AGDPGVEVELPPATAGSSH"
     gene            3112..3618
                     /locus_tag="STPH1_RS11560"
                     /old_locus_tag="STPH1_2311"
     CDS             3112..3618
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="STPH1_RS11560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2311"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_153178026.1"
                     /transl_table=11
                     /translation="MDFVIRRATAEEYDTLGEITAQAYLRDGLLDFGESDSYLDELRDV
                     AKRAAAAEVLVAVADGRVLGGVTFVPSGGPMADIARPGEAEIRMLAVAREARGRGAGEA
                     LVRACVDRARAVPGCTGVVLSTQAAMRTAHRLYERLGFVRTPDRDWNPLPELDDIMLLA
                     YALTL"
     misc_feature    3654..3668
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     regulatory      3679..3840
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    3685..3699
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     gene            3966..6341
                     /locus_tag="STPH1_RS11565"
                     /old_locus_tag="STPH1_2312"
     CDS             3966..6341
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444560.1"
                     /locus_tag="STPH1_RS11565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2312"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_164383285.1"
                     /transl_table=11
                     /translation="MTIAPADPASAAPVTATGEPDGPGAALLRTLTGLTADLPGADPGR
                     VAAAALRGRSAHADEAELRELATEAAAGLISEDPVYSRLAARLLTIGIRAEAASQGVVA
                     FTDSVATGHREGLIADRTAAFVRLHAARLDALVDRDADDRFGYFGLRTLYSRYLLRHPI
                     TRKTVETPQHFLLRVAAGLAEDDTTRSVDEVAALYGLMSRLDYLPSSPTLFNSGTRHAQ
                     MSSCYLLDSPRDELDSLYDRLHQVARLSKHAGGIGIAYSRVRARGSLIRGTNGHSNGIV
                     PFLKTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEDARRTHNLNLAHW
                     IPDEFMRRVDADGTWSLFSPADVPELTDLWGEEFDAAYRRAEEAGLARRTLPARELYGR
                     MMRTLAQTGNGWMTFKDTANRTANQTATPGHVVHSSNLCTEILEVTDDGETAVCNLGSV
                     NLGAFVDPAKGDMDWERLDATVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGAMG
                     LQDVFFQLRMPFDSPAAKALSTRIAERIMLAAYETSADLAERNGPLPAWEKTRTAQGVL
                     HPDHYGVEPAWPERWTALRARMAATGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLF
                     KRETLSGEFLQVNSYLVDDLKRLGVWDARTREALREANGSVQGFSWIPEDVRALYRTAW
                     EIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKQGLKTTYYLRSRPA
                     TRIARAAGRATTVPVQAAPDPEAVACSLENPESCEACQ"
     gene            6341..7372
                     /locus_tag="STPH1_RS11570"
                     /old_locus_tag="STPH1_2313"
     CDS             6341..7372
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973746.1"
                     /locus_tag="STPH1_RS11570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2313"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_153178028.1"
                     /transl_table=11
                     /translation="MTTETPATTATKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWHV
                     EEVDLHSDVADLAKLSPMEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLS
                     RQLFEEAVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFRWMDSVESIDR
                     LETKADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMH
                     MSFAFDVVDTVRKEEPELFDDELRQQVTDMLREAVEAELQFARDLCGDGLPGMNTDSMR
                     QYLECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLD
                     EDF"
     gene            complement(7285..7542)
                     /locus_tag="STPH1_RS11575"
                     /old_locus_tag="STPH1_2314"
     CDS             complement(7285..7542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973747.1"
                     /locus_tag="STPH1_RS11575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2314"
                     /product="hypothetical protein"
                     /protein_id="WP_153178029.1"
                     /transl_table=11
                     /translation="MTGNQIEGLVGMLATLGLLVLMVLPSVIGIVRDRRIDRQIREAQE
                     DGESRVRHEKETQKSSSRSTVPSTATWYAEGRRSKKLVNS"
     gene            7635..8603
                     /locus_tag="STPH1_RS11580"
                     /old_locus_tag="STPH1_2315"
     CDS             7635..8603
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030121.1"
                     /locus_tag="STPH1_RS11580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2315"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_153178030.1"
                     /transl_table=11
                     /translation="MLRNVAAVLLDGAHPFELGVICEVFGIDRSDEGLPGYDFAVVSAE
                     GPELTTHVGGLTVSTPYGLERLEEADLIAVPAGSDFVRREYPPDLLDALRRATDRGTRV
                     LSVCSGAFVLGAAGLLDGRRCAVHWHHAAELSRQYPRARVAPDVLYVDEDPVITSAGTA
                     AGIDACLHIVRKEQGTEVANRIARRMVVPPHRDGGQAQYIERPLPRSSCDTVGEVLAWM
                     EQHLDEEVTVEQLAARAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETM
                     DAIAWRAGFGTAAALRHQFVRTLGTTPHAYRRTFRGPEAAA"
     gene            complement(8619..10004)
                     /locus_tag="STPH1_RS11585"
                     /old_locus_tag="STPH1_2316"
     CDS             complement(8619..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="STPH1_RS11585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2316"
                     /product="cytochrome P450"
                     /protein_id="WP_164383286.1"
                     /sec_met_domain="p450 (E-value: 5.3e-70, bitscore: 235.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVNPETRAPGAPGAPELREPPVAGGGVPLLGHGWRLARDPL
                     AFMSQLRDHGDVVRIKLGPKIVYAVTNPELTGALALNPDYHIAGPLWESLEGLLGKEGV
                     ATANGPLHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWQAGRTIDATSESFRIAV
                     RVAARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLGPLYRLPLPANRRFNDALAD
                     LHLLVDEIIAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIAS
                     TIMWLLQALADHPEHADRIRDEVEAVTGGRPVAFEDVRKLTHTGNVIVEAMRLRPAVWV
                     LTRRTVAESELGGYRIPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAKNVPKYA
                     MKPFSAGKRKCPSDHFSMAQLTLITAALATKYRFEQVAGSNDAVRVGITLRPHDLLVRP
                     VAR"
     gene            complement(10001..11086)
                     /gene="cyc1"
                     /locus_tag="STPH1_RS11590"
                     /old_locus_tag="STPH1_2317"
     CDS             complement(10001..11086)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="STPH1_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2317"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_205616665.1"
                     /sec_met_domain="T1TS (E-value: 4.4e-64, bitscore: 216.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAFSHGTTATPTAIAVPSSLRLPVIEAAFPRQLHPYWPKLQETT
                     RAWLLEKRLMPADKVHEYADGLCYTDLMAGYYLGAPDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRPGAWRRLRGRLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPDTWNARFAR
                     HFHAVIEAYDREFHNRTRGIVPGVEDYLELRRLTFAHWIWTDLLEPSSGCELPDAVRKH
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVE
                     ECISEFLAVEQDALRFADGLADGTVRGKELSGAVRANVGNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     misc_feature    complement(10202..10204)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11346..11996)
                     /gene="def"
                     /locus_tag="STPH1_RS11595"
                     /old_locus_tag="STPH1_2318"
     CDS             complement(11346..11996)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="STPH1_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2318"
                     /product="peptide deformylase"
                     /protein_id="WP_164383288.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHPGVLPVDDDGFVVDTQDCEEREADWRGRGTSRPIT
                     VVGNPVLHKECEDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVSKKVFVYDCPDD
                     EGVRHVGVVCNPELVELPADRRSLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPV
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            complement(12077..13057)
                     /locus_tag="STPH1_RS11600"
                     /old_locus_tag="STPH1_2319"
     CDS             complement(12077..13057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="STPH1_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2319"
                     /product="hypothetical protein"
                     /protein_id="WP_153178034.1"
                     /transl_table=11
                     /translation="MRIFGKARHRPSASWRQATDRAFTLIGDGRYDDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDGGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRTPGDATDASEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARVEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLLEAATEADRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPAGLVKGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13171..14511)
                     /locus_tag="STPH1_RS11605"
                     /old_locus_tag="STPH1_2320"
     CDS             complement(13171..14511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444569.1"
                     /locus_tag="STPH1_RS11605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2320"
                     /product="metal-dependent phosphohydrolase"
                     /protein_id="WP_240469000.1"
                     /transl_table=11
                     /translation="MRPFPSRVPTPSPPRHGRGRPDTSPGRAATGRSPSSAPAALLLVP
                     GGAGLLALGCLASVLVAEPAQRPVALAFGGLVALGELTRRAGAEAREAAPLGAAGALAY
                     ALLGDVAGQPAHHGVAQTVTVVLAASLLGSVPHVARGGGPVLHPLARRVLTVGFAAVCF
                     RPLSNQGVFDDWSGPAYALLLLGLLALTTLCDAVLAVAPAHARTGWPFGPLLREELRGM
                     VGITSAVCATGAVMALAVSVAGLWALPVFSVPLLLAQLSYRRYAAVRATYRQTIASLAR
                     ATEIAGYTPAGHARRVAGLGVAVGRDLGLSGAELTVLEYAALMHDIGQLSLVDPVPAGA
                     TADLPVAEQRRIALLGGAVVRQTGVDAAVAVVVERQADPCREQPVAARIVRVVNAYEEK
                     ARDAGPGGVLTALEELRLATAGDYAPEVVEALARVLSRGSLTEPAAG"
     gene            complement(14675..15991)
                     /locus_tag="STPH1_RS11610"
                     /old_locus_tag="STPH1_2321"
     CDS             complement(14675..15991)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973754.1"
                     /locus_tag="STPH1_RS11610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2321"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_164383289.1"
                     /transl_table=11
                     /translation="MDAVPARARAYVVCVALVALLCLRPLPSVHAPWWAVLLLAGLYAG
                     SELVARSRFVGTCYPVLLAGAFLLPPPAAALVALPGALLSPVPRRPSGLRRVWRAAQLT
                     LAVWAAACVHWRLGGRDAVVEPAFPYALLPAGAAVLAFCLVLTLLDGGILTLADRVPPS
                     RAWRGLFSRSLAPIAVHGLAGLMMAVLWRSPYGPVAALLVLLPMCVAWWAFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMDDERVETLRFAGILHDVGK
                     LGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIRFLGEARAAVLHHHERLDGSGYP
                     YGLVGDRIPESARVVAVADAFDAMTSTRSYSRARPVAAALEELRRCAGAQFDPRMVRAL
                     VHALGRHGWRPAVTADGTPARADPVPGGGARDRVGKGAT"
     gene            complement(16117..16428)
                     /gene="rsrA"
                     /locus_tag="STPH1_RS11615"
                     /old_locus_tag="STPH1_2322"
     CDS             complement(16117..16428)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="STPH1_RS11615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2322"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_061442628.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDKEMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPGDLRAKVMGRLDLIRSGQSVPEHDVTATPSAPQES"
     gene            complement(16425..17108)
                     /gene="sigR"
                     /locus_tag="STPH1_RS11620"
                     /old_locus_tag="STPH1_2323"
     CDS             complement(16425..17108)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="STPH1_RS11620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2323"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_003973756.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPEGRGTGAESTAERSARFERDALEFLD
                     QMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKK
                     QREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIAV
                     YLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGESNEA
                     KGSGS"
     misc_feature    complement(17071..17086)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            complement(17387..18022)
                     /locus_tag="STPH1_RS11625"
                     /old_locus_tag="STPH1_2324"
     CDS             complement(17387..18022)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="STPH1_RS11625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2324"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_164383291.1"
                     /transl_table=11
                     /translation="MTEAVETDAGSARITWHRARDPRLVLALSHGAGGGIEARDLTALA
                     AALPAHGVSVALVEQPWRVAGKKLAPAPKTLDTGWRGVWPALTAPGPPVISGGRSAGAR
                     VACRTAGELGAHAVLALSFPLHPPGKPEKSRADELLRAGVPTLVVQGGNDPFGRPEEFP
                     EAPAGTYDLIEVPYGDHGFAVPKRAETTQEQALRVITDGVLKWIGALG"
     gene            complement(18045..18860)
                     /locus_tag="STPH1_RS11630"
                     /old_locus_tag="STPH1_2325"
     CDS             complement(18045..18860)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="STPH1_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2325"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_164383292.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEIEKWEPKESLEPDYNVAPTKEVYAVL
                     DRPLKDVEDPKPVRQLRKLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFSTRR
                     CILPADGYYEWVTGKQERDLEVEGRKKRPRKQPYFVTPADGSVFAMAGLYEFWRDRTLP
                     DDHPQAWWVTCSVITTEAETTPLAVAPADGPYALADIHPRMPLMLTPDRWDDWLDPART
                     DPDGLTSLLTPPPTGLMRAFPVSTAVSNVRNNGPELLKELEAPEEGTLF"
     gene            18911..19633
                     /locus_tag="STPH1_RS11635"
                     /old_locus_tag="STPH1_2326"
     CDS             18911..19633
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973759.1"
                     /locus_tag="STPH1_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2326"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_153178038.1"
                     /transl_table=11
                     /translation="MDHLATASLTSLWDEVSGTQPDPDLWVVIATLVAALAVVATRGSW
                     RIARNAITIAHEGGHGLVALLTGRTLTGITLHSDTSGLTVSRGKPHGVGMILTAVAGYT
                     APPLLGLGGAALLAAGRITLLLWLATALLVALLVMVRNAYGVLTVVVTGGTFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLARLTHAPAGVWFFLF
                     HAVSLCSLIGGGRWLLEL"
     gene            19766..21082
                     /gene="aroA"
                     /locus_tag="STPH1_RS11640"
                     /old_locus_tag="STPH1_2327"
     CDS             19766..21082
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824681.1"
                     /locus_tag="STPH1_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2327"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_153178039.1"
                     /transl_table=11
                     /translation="MTVNPAHTALWSAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTVLMAEALRAMGVEIEEGVGPDGTGEFWRVIPAGLRGPATVDVGNAG
                     TVMRFLPPVATLADGAVRFDGDPRSYERPLHGVIDALRVLGARIDDDGRGALPLTVQGG
                     GALEGGPVEIDASSSSQFVSALLLSGPRFNQGVEVRHTGSALPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGKVVIPDWPSRT
                     TQPGDRLREIFTEMGGSCELTDFGLVFTGSGAIRGIDVDLSEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGVFHTYEDHRM
                     ATAGAVLGLAVEGVQIENVATTAKTLPDFPDLWTGMLGA"
ORIGIN
        1 gcaagcgaca gttcgggcgg accgggaccg ggtgtaccac cccccaccga atgacctgcc
       61 ggccgggctc cgaacgcgcg taccagcgac gcctgacccc cctgtggact agaccaaggg
      121 tgttcccccg ggtatacaga ggggatcacg gagcgtgcgg gggccatccc ggcgcgaagc
      181 cgtgccacga tgtgagccgt ggccgacagg gaagcggtcg cttcggcacc cggagccggg
      241 aaggcagagc atgagcaccg acgtcagcag tgcggagaac gagggtgggg cgaccgtccg
      301 taccgcgcgc gtgcccaagt actaccgtct gaagaagcat ctgctcgaca tgacccggac
      361 ccagacgccg ggcacaccgg tcccgcccga gcgcaccctg gccgccgagt tcgacacctc
      421 gcgcacgacg gtgcgccagg ccctccagga gctggtcgtc gagggccgcc tggagcgcat
      481 ccagggcaag ggcaccttcg tcgccaagcc caaggtgtcg caggcgctgc aactcacctc
      541 gtacaccgag gacatgcggg cccagggtct cgaaccgacc tctcagctgc tggacatcgg
      601 ctacatcacc gccgacgacc ggctcgccgg actgctggac atcacggccg gcggccgggt
      661 gctgcgcatc gagcggctgc gcatggccaa cggcgaaccg atggccatcg agaccaccca
      721 cctcagcgcg aagcgcttcc cggcgctgcg ccgctccctg gtgaagtaca cgtccctcta
      781 caccgcgctc gccgaggtgt acgacgtcca tctcgcggag gccgaggaga ccatcgagac
      841 ctccctggcc accccgcgcg aggccggcct gctcggcacc gacgtgggcc tgcccatgct
      901 gatgctctcc cggcactcgc aggaccgcac cggtcagccg gtggagtggg tgcgctcggt
      961 ctaccggggc gaccgctaca agttcgtggc ccgcctcaag cggccccagg actagacctg
     1021 cccgcccggc acataaccgg catacctcca cgcgcgcggg cgcgaagttg cggttgagga
     1081 ccgatatacg gacgaggtct tccgctgtct tgacaccgtc acctacattt cgtgcgcact
     1141 gcacgaggtg atcagcgagg ggacggagcc gcgcatgtca gaagacacag aagtgagcag
     1201 agagccggtg gtgacgccgg tgcgcgtcgt catcgggttc tgtctcgtcg caccgttcgt
     1261 ggccatgctg tgggtcggtt cgtacgcgaa gacggacccg gacttcatcg gcatcccgtt
     1321 cttctactgg taccagatgg cctgggtact gatctccacc ctgctgacgg tgaccgcgta
     1381 caagctgtgg cagcgcgacc agcgcggacg ccgggaaggc ggggccaagt gaacgacggc
     1441 gtgaacggcg tcgcactcgc cgtcttcatc ttcttcttcg tgctcgtcac cgccatgggc
     1501 ttcctggccg cgcgctggcg caaggccgag aacgagcaca gcctcgacga gtggggcctc
     1561 ggcggccgct cgttcggcac ctgggtcacc tggttcctgc tgggcggcga cctgtacacc
     1621 gcgtacacct tcgtggccgt cccggcggcg atctacgcgg cgggcgcggc cggcttcttc
     1681 gcggtgccgt acacgatcct ggtctacccg ctgatcttca ccttcctgcc ccgcctgtgg
     1741 tcggtctccc acaagcacgg gtacgtgacg acctcggact tcgtgcgcgg acggttcggc
     1801 tccaagggcc tgtcgctggc ggtcgccgtc acgggcatcc tggcgaccat gccgtacatc
     1861 gcgctccagc tggtcggcat ccaggccgtg ctcgacgtga tgggcgtcgg tggcggcgag
     1921 gacaccaact ggttcgtcaa ggacctgccg ctgctgatcg ccttcggtgt gctggcggcg
     1981 tacacgtact cgtcggggct gcgcgcgccc gcgctgatcg cgttcgtgaa ggacacgctg
     2041 atctacatcg tcatcgcggt ggcgatcatc tacatcccga tcaagctggg cggcttcgac
     2101 gacatcttcg cgtcggcgag cgacaagttc accgagtcgg gcaagggtgg agtggtgccc
     2161 gactccgggg gccagtggac gtacgcgacg ctcgcgctcg gctcggccct ggcgctgttc
     2221 atgtacccgc actcgatcac cgcgacgctg tcctcgcgca gccgtaacgt gatccggcgc
     2281 aataccacga tcctgccgct gtactcgctg atgctgggcc tgctcgcgct gctcggcttc
     2341 atggcgatcg cggccggggt caaggtggag aacggccagc tggcgatccc gcagctgttc
     2401 gagaacatgt tcccggactg gttcgcgggc gtggccttcg cggcgatcgg catcggcgcg
     2461 ctggtcccgg cggcgatcat gtcgatcgcg gccgcgaacc tcttcacccg caacatctac
     2521 aaggacttca tcaagccgga cgccacgccg cagcaggaga ccaaggtctc caagctggtg
     2581 tcgctgctgg tgaaggtggg cgcgctgatc ttcgtcctgg gcatggacaa gaccgtcgcg
     2641 atcaacttcc agctgctggg cggcatctgg atcctgcaga ccttcccggc cctggtcggc
     2701 ggcctgttca cccgctggtt ccaccgctgg gcgctgctcg gcggctgggc ggtcggcatg
     2761 gtctacggca cggtcgccgc ctacggtgtc gcctcgccga cgcagaagca cttcggcggc
     2821 tcctccgacg agatccccgg catcggcgag atcggctaca tcggcctcac cgccttcgtg
     2881 ctgaacgtcc tggtcaccgt ggtcctgacc ttcgtcctga gggcggtcaa ggcgcccgac
     2941 ggcgtcgacg agacccagcc gagcgactac acggcggacg ccggcgatcc gggcgtcgag
     3001 gtggaactgc cgccggccac ggcgggcagc tcgcactgat ccccggttcg aggcgggccg
     3061 tcggagaaat ccggcggccc gttgtcgtac ccgtcgggca cactcggcgt catggacttc
     3121 gtgatccggc gggcgacggc cgaggagtac gacaccctcg gcgagatcac cgcgcaggcc
     3181 tacctgcgcg acggcctcct cgacttcggg gagagcgatt cgtacctgga cgagctgcgc
     3241 gacgtggcca agcgggcggc ggccgccgag gtgctggtcg ccgtggccga cggccgggtg
     3301 ctcggcggcg tgaccttcgt gccgtccggc ggccccatgg cggacatcgc gcgccccggc
     3361 gaggccgaga tacgcatgct cgccgtcgcc cgggaggcac gcggccgcgg ggccggcgag
     3421 gccctcgtgc gggcctgcgt cgaccgcgcc cgggccgtgc cggggtgcac cggcgtcgtg
     3481 ctgtcgaccc aggccgccat gcgcaccgca caccgcctct acgagcgtct gggcttcgtc
     3541 cgcacgcccg accgcgactg gaaccccctg ccggagctgg acgacatcat gctgctcgcc
     3601 tacgcactga cgctctgaca cggtcgcggc acccgtcaca acaccccacc aggacacaac
     3661 atctgggggt gctcgcgtcg ccgggcacaa gatgtatgct cgtgctcgct gtcgccgcag
     3721 gggaatccgg tgcgaatccg gaactgtccc gcaacggtgt acttgcgtgc atccgtacgt
     3781 cttcgcacgt acgcgcacgc ctgtccagtc cgaggacctg ccgacggtgc gcccggccgc
     3841 cctggcccgg gtgccatgac gtccgggcct cgtggagtgg gccggtggac gcgacgccgc
     3901 gtgcgctcgt gagctgcccc gccctccctc cgccaggccc cgtgccgagc gagggagtgc
     3961 tccacgtgac catcgcgcca gccgatccgg cttcagcggc cccggtgacg gcgaccgggg
     4021 aacccgacgg acccggtgcc gcactgctgc ggaccctgac cgggctgacc gccgacctcc
     4081 ccggcgccga ccccggccgg gtggccgccg ccgcactgcg cggccggtcc gcccacgccg
     4141 acgaggccga gctgcgggag ctggccaccg aggcggccgc cggtctgatc tccgaggacc
     4201 cggtctactc ccggctggcc gcccggctgc tgaccatcgg catccgcgcc gaggccgcct
     4261 cccagggtgt cgtcgccttc accgactccg tggccacggg ccaccgcgag ggcctgatcg
     4321 ccgaccgcac cgccgccttc gtccggctgc acgcggcccg cctggacgcg ctggtcgacc
     4381 gggacgccga cgaccgcttc ggctacttcg gcctgcgtac gctctacagc cgctacctgc
     4441 tccgccaccc gatcacccgc aagaccgtcg agacgcccca gcacttcctg ctgcgggtcg
     4501 ccgccggact cgccgaggac gacaccaccc ggtccgtgga cgaggtcgcc gccctctacg
     4561 gcctgatgag ccgcctggac tacctcccgt cctcccccac cctcttcaac tccggcaccc
     4621 ggcacgccca gatgtcgtcc tgctacctcc tggactcccc cagggacgag ctggactccc
     4681 tctacgaccg cctgcaccag gtggcccgcc tgtccaagca cgccggcggc atcggcatcg
     4741 cctactcccg cgtccgcgcc cggggttcgc tgatccgcgg caccaacggg cactccaacg
     4801 gcatcgtccc gttcctgaag acgctggacg cctcggtcgc cgccgtgaac cagggcggcc
     4861 ggcgcaaggg cgcggcggcc gtctacctgg agacctggca cgcggacgtc gaggagttcc
     4921 tggagctgcg ggacaacacc ggcgaggacg cccgccgtac gcacaacctg aacctcgcgc
     4981 actggatccc ggacgagttc atgcgccgcg tggacgccga cgggacctgg tcgctgttct
     5041 cccccgccga cgtgcccgag ctgaccgacc tgtggggcga ggagttcgac gccgcgtacc
     5101 gcagggcgga ggaggcgggg ctcgcccgca ggacgctgcc cgcccgggag ctgtacggcc
     5161 gcatgatgcg caccctcgcg cagaccggca acggctggat gacgttcaag gacaccgcca
     5221 accgcacggc gaaccagacc gcgacccccg gtcacgtcgt ccactcctcc aacctgtgca
     5281 cggagatcct ggaggtcacc gacgacgggg agacggcggt ctgcaacctg ggctcggtca
     5341 acctcggcgc cttcgtcgac cccgcgaagg gcgacatgga ctgggagcgc ctggacgcca
     5401 ccgtccgcac cgccgtgacc ttcctcgacc gggtcgtcga catcaacttc tacccgaccg
     5461 agcaggcggg ccgctccaac gcccgctggc gcccggtcgg tctcggcgcg atgggcctcc
     5521 aggacgtctt cttccagctc cgcatgccct tcgactcccc cgcggcgaag gcgctgtcca
     5581 cccgcatcgc cgagcggatc atgctcgccg cgtacgagac ctccgccgac ctcgccgaac
     5641 gcaacggccc gctgccggcc tgggagaaga cccgtacggc ccagggggtg ctgcacccgg
     5701 accactacgg cgtcgagccc gcctggccgg agcgctggac cgcgctgcgc gcgcgcatgg
     5761 cggcgaccgg gctgcgcaac tccctgctcc tggccatcgc cccgaccgcg accatcgcct
     5821 ccatcgccgg tgtctacgag tgcatcgagc cgcaggtctc caacctgttc aagcgcgaga
     5881 cgctgtcggg cgagttcctc caggtcaact cgtacctggt ggacgacctc aagcggctcg
     5941 gcgtgtggga cgcccgtacc cgtgaggcgc tgcgcgaggc caacggctcc gtgcagggct
     6001 tctcctggat ccccgaggac gtgcgcgcgc tgtaccgcac cgcctgggag atcccgcagc
     6061 gcggcctgat cgacatggcc gccgcccgca ccccgtacct cgaccaggcc cagtcgctga
     6121 acctgttcct ggagacgccg accatcggga agctctcctc gatgtacgcg tacgcctgga
     6181 agcagggcct gaagaccacc tactacctgc gctcgcgccc ggcgacccgg atcgcccgcg
     6241 ccgcgggccg cgccaccacc gtccccgtgc aggccgcccc ggaccccgaa gcggtcgcct
     6301 gctccctgga aaaccccgag tcctgcgagg cctgccagta atgaccaccg agacccccgc
     6361 gaccaccgcc acgaagaacc tgctcgaccc gggcttcgag ctgaccctgc gccccatgcg
     6421 ctacccggac ttctacgagc gctaccggga cgccatcaag aacacctggc acgtcgagga
     6481 ggtcgacctc cactcggacg tcgccgacct ggcgaagctc agcccgatgg agcagcacct
     6541 gatcggccgg ctcgtggcct tcttcgccac cggcgactcg atcgtcgcga acaacctggt
     6601 gctgaccctc tacaagcaca tcaactcccc cgaggcgcgg ctgtacctgt cccgccagct
     6661 cttcgaggag gccgtccacg tccagttcta tctgacgctc ctggacacct acctgcccga
     6721 cccggaggac cgcgccgccg ccttcgcggc cgtggagaac atcccgtcca tccgggagaa
     6781 ggccgagttc tgcttccggt ggatggactc ggtcgagtcg atcgaccgcc tggagaccaa
     6841 ggccgaccgc cgccgcttcc tgctcaacct gatctgcttc gcggcgtgca tcgagggcct
     6901 gttcttctac ggcgccttcg cctacgtcta ctggttccgc agccggggcc tgctgcacgg
     6961 tctggccacc ggcaccaact gggtgttccg ggacgagacc atgcacatgt ccttcgcgtt
     7021 cgacgtcgtc gacaccgtcc gcaaggagga gccggagctg ttcgacgacg agctgcggca
     7081 gcaggtcacc gacatgctga gggaggccgt cgaggccgag ctgcagttcg cgcgcgacct
     7141 gtgcggtgac ggcctcccgg ggatgaacac cgactcgatg cggcagtacc tggagtgcgt
     7201 ggccgaccag cgtctgaccc ggctcggctt cgccccggtg tacggctccg agaacccctt
     7261 ctccttcatg gagcttcagg gcgttcagga gttgaccaac ttcttcgagc ggcgcccctc
     7321 ggcgtaccag gtggcggtgg aaggcaccgt cgacctggac gaggacttct gagtctcctt
     7381 ctcgtggcgg acccggctct ccccgtcctc ctgggcctcc ctgatctgac ggtcgatgcg
     7441 cctgtcgcgc acgatgccga tcaccgaggg caggaccatg aggacgagga gtccgagggt
     7501 cgcgagcatt ccgacaaggc cttctatctg gtttccggtc atgacaccac tgtcgcgccg
     7561 gatgctcctt accgtcagtg gcaggactgc cgtaagacct cgatttcctg ccaccggcga
     7621 ggcacactgg cggcatgctg cgcaacgtgg ccgccgttct gctggacggc gcgcatccct
     7681 tcgaactcgg cgtgatctgc gaggtcttcg gcatcgaccg gagcgacgag ggcctgccgg
     7741 ggtacgactt cgcggtggtc tccgcggagg gccccgagct gaccacccac gtcggcggac
     7801 tgaccgtctc gacgccgtac ggtctcgagc ggctggagga ggccgacctg atcgcggtgc
     7861 cggcgggcag cgacttcgtc cgccgggagt acccgcccga cctgctggac gccctgcgcc
     7921 gggcgacgga ccggggcacc cgcgtactga gcgtgtgctc cggcgccttc gtgctgggcg
     7981 cggccggcct gctggacggg cggcggtgcg cggtgcactg gcaccacgcg gccgagctga
     8041 gccggcagta cccgcgggcc cgggtggcac cggacgtgct ctacgtcgac gaggacccgg
     8101 tcatcacctc cgccgggacg gccgccggca tcgacgcctg cctgcacatc gtgcgcaagg
     8161 agcagggcac ggaggtcgcc aaccggatcg cccggcgcat ggtggtgccg ccgcaccggg
     8221 acggcgggca ggcgcagtac atcgagcggc cgctgccgcg ctcctcctgc gacaccgtcg
     8281 gcgaggtgct ggcctggatg gaacagcacc tcgacgagga ggtcaccgtc gagcagctcg
     8341 ccgcacgggc gcacatgtcc ccgcgcacct tcgcccgccg cttccagcag gagacgggga
     8401 cgacccccta ccgctggatc ctgcgccagc gggtgctgct ggcccagcgg ctcctcgagg
     8461 cgacggacga gacgatggac gcgatcgcct ggcgcgccgg tttcggcacg gcggcggccc
     8521 tgaggcacca gttcgtccgg accctgggca ccaccccgca cgcctaccgg cgcaccttcc
     8581 ggggcccgga ggccgccgcc tgattcccta cggccgcgtc accgcgccac cggcctgacc
     8641 agcaggtcgt gcggacgcag cgtgatgccg acccggaccg cgtcgttcga acccgccacc
     8701 tgctcgaagc ggtacttcgt ggcgagcgcg gccgtgatca gcgtgagctg cgccatcgag
     8761 aagtggtcgc tggggcactt ccgcttgccc gcactgaacg gcttcatggc gtatttcggc
     8821 acattcttcg cgcgttccgg cagccaccgg tccgggtcga actccaggtt gtcgtcgtac
     8881 gacttcggat cgcgttggat tgcgtacgga ctgtagatga tgtccgcacc ggccggaatg
     8941 cgatagccac cgagttcgct ctcggccacc gtgcgccgcg tcaataccca tacggcggga
     9001 cgcaaacgca tggcctccac gatgacattg ccggtgtgcg tgagcttccg gacgtcctcg
     9061 aatgccacgg gacgcccgcc ggtgaccgcc tcgacttcgt cgcgtatgcg gtcggcatgt
     9121 tccggatggt cggcaagtgc ctggagcaac cacatgatcg tggacgcgat ggtttcactg
     9181 cccggggtga gtatcgcgac cacctggtcg tggatctcct gttccccgat cgggtcgcca
     9241 ttgtcgtcct tcgcctccag caatgccgtg agcaaatcgt ccggcttttg accggatgcc
     9301 cggcgttcgg cgatgatctc gtcgaccagc aggtgcagat cggccaatgc gtcgttgaat
     9361 cggcggttgg ccggaagcgg cagccggtag agcggtccga gcgggaccac catgcgccgg
     9421 tacatgcccc ggaagacggt ggcgagcgcg acgcacagcc gctcggcccg ctcgtccatg
     9481 tactgcccgc gcagcaggca gcgggccgct acgcgcacgg cgatccggaa ggactcggag
     9541 gtcgcgtcga tcgtccggcc ggcctgccag cgctcggtga gcgcgtgggc ctcctcctcc
     9601 atgatcggcc cgtaggcggg gatggcgtcg agccggaacg ccggctggat ggtgcgccgc
     9661 tggcgccggt ggagcggacc gttggcggtg gccacaccct ccttgccgag cagcccctcc
     9721 agcgactccc acagcgggcc cgctatgtgg tagtcggggt tcagggcgag ggcgccggtc
     9781 agctcggggt tcgtgaccgc gtagacgatc ttggggccga gcttgatgcg cacgacgtca
     9841 ccgtggtcgc gcagctggga catgaaggcc agcgggtcgc gggccagccg ccagccgtgg
     9901 ccgagcagcg gcacgccgcc gcccgcgacg ggcggttcgc gcagctccgg tgctcccggt
     9961 gcgcctggtg cacgggtttc ggggttgacg gactcgacgg tcatttctca cctgccgctt
    10021 cgttgttgac gtacgggggc gtggaccggt cgtcccagct gtcgaccatg tagcggccgg
    10081 actcgtggtg gaaccagtag acggaactga accagttccg catattgccg acgttggccc
    10141 gtacggcgcc gctcagttcc tttccgcgta cggttccgtc ggcgagtccg tcggcgaacc
    10201 gtaaggcgtc ctgctccacg gcgaggaatt cggagatgca ttcctcgacg cgtcgcctga
    10261 cttctccgat ggcttcttcc agcgtgagtg aatgatgggt gatgagactg attccgagat
    10321 tgtggacctc gtcccccgct atttccttcg gcagtgagca gaggtcgttg taccaggcgg
    10381 cgaattcctg actcagcagc gccgcccggc ggtatgccgg gtgtttccgt acggcgtcgg
    10441 ggagttcgca tcccgaactc ggctccagca ggtcggtcca gatccagtgc gcgaaggtga
    10501 gccggcgcag ttcgaggtag tcctcgacgc cgggcacgat tccgcgcgtg cggttgtgga
    10561 attccctgtc gtacgcctcg atcaccgcgt ggaagtgccg ggcgaaccgg gcgttccagg
    10621 tgtccggcag gaaggcgtag agccgccgga cgctgtcggc gaacccggcc accagcgtgt
    10681 cctcgtggtg caggtggtcc ccgggtgagt cgagcgccgt gtgcagccgg ccgcgcagcc
    10741 gccgccaggc gccgggacgg ccgtggacga tgtcgcggtc gtgccggtcg tcccagacga
    10801 agaaccacgc gctgtagtcc gctatcgcct gcatgacctc gtcgggtgcg ccgaggtagt
    10861 accccgccat gaggtccgtg tagcacagac catcggcata ttcatggacc ttgtccgccg
    10921 gcatgagccg cttttcgagc agccaggcgc gggtggtctc ctggagcttc ggccaatacg
    10981 gatgcagttg ccggggaaat gccgcctcga tcaccggaag acggagcgat gacggtactg
    11041 cgatcgcggt cggtgtcgct gtggtgccgt gtgagaaagc atgcacgaac aaacccctct
    11101 cagccgccgg tggcgcaccc ctctccctga gcggggcgtg cgccgttgcg tatccccgca
    11161 cttcccattc agcaccacaa ctgaccgttc tgggaacgga tttgcttcat tcactacccc
    11221 ccgatgccgg aattctcctg ttgtgtggcg gctttccgta gacgcacaca gacgaacggc
    11281 gcccgctcgg gggagacccg aacaggcgcc gtgcgcaagg gagatgtggg gcgggtgagg
    11341 cggtgtcagt cgttcgcgac gacggggtag cgcggctcgt tctcggccat ctgccgcagt
    11401 gcgtccttgc gttcgcgctt ggagagccgg tcgatgtaca ggtacccgta caggtggtcc
    11461 gtctcgtgct gcaaacaccg tgcgaagtac ccggtgccgc gcaccttgac ggggttgccc
    11521 ttctcgtcct gcccggtcac ctcggcgtag tcggggcggg cgagcggcgc gtaggcggtc
    11581 ggcacggaca ggcagccctc gttgctgtcg tccaggctgc ggcggtcggc gggcagttcg
    11641 accagctcgg ggttgcagac cacgccgacg tgacggacgc cctcgtcgtc ggggcagtcg
    11701 tagacgaaga ccttcttgga gacgccgatc tggttggcgg ccaggcccac gccctcggcg
    11761 gtgcgctggc tggcgaacat gtcggccacc agctgctgga actcctcgcc gaagtcggtg
    11821 acgtcctcgc actccttgtg cagcaccggg ttgccgacca ccgtgatcgg acgcgaggtg
    11881 ccgcgcccgc gccagtcggc ctcacgctcc tcgcagtcct gggtgtcgac gacgaacccg
    11941 tcgtcgtcca cggggagcac gcccgggtgc tgctgatcgg tgtcctgctg ggccatgacc
    12001 gacgtatgcc ttcctcgtac aaccaaaggg tgctgctgac gctgatgaag tgtcctggca
    12061 aagactacgg ggccgctcag cagacctctt ccaggtcccg ccagtcacgc gagtccgggc
    12121 tgtccgccac ccacccgtcc agcaacccct tcaccagccc cgccggcgca gccaccccgc
    12181 actcccgctc cggcacccac agctgcccgt cggtgcggtg cccgagcggc ccggggtggc
    12241 cgggttcgct gtggtcgtgc gggtcgaggt gctcgccctc gccctcgtcg gacggcatcc
    12301 gggactccga gcacatccgg cacagcagcc ggacggacga cgaccagtcc tcggccgcga
    12361 acccggcgtc ggcggccagc tgctccaggg cgtcccggtc ggcctcggtg gcggcctcca
    12421 ggaggaccac ccaggtgggc acgggcgagg gcgcccacag ctcgatctcg tcgaagacgg
    12481 ggtaggagtg cccggcgctg gtcgtccgct ccccgtgcgg cacgccgtcg tgcaggacga
    12541 cctcgcccca ccggcgcccg gacgacggca gcgggatgga cagcacctcg acgcgggcgg
    12601 ggtcgagccg ccggccccac accacctcgg cctcgccctc cggggacagc cgtacggccg
    12661 cgctgccgag gtccatgccg agcggctcgc tcgcgtccgt ggcgtccccc ggggtgcgca
    12721 ggccgtaggc ctgccaggcg cggcgggcca gcggccagtc ctggagggcg gtcgcggcga
    12781 tgccgacgtt ccaccagtcg ggggctccgc cgtcccggtc gagcagcgcg acggccctga
    12841 ggccggccgc cctggcctgc tcccagtcgt gccggaactt gtgcagcagc gccaggttga
    12901 accaggactc ggacagccag ggctccagat ccgccgctcg tgtcagcagc gcccccgcgt
    12961 cgtcgtagcg accgtcgccg atcagcgtga acgcgcggtc ggtggcctgc cgccaggagg
    13021 cggagggccg gtgccgtgcc ttgccgaaga tcctcacgat tcccgcctgc cagttccgtt
    13081 cagtgggctg gctgtgcctt tcgcgccccc ggacaccctc tcccgggcat caaaccacgt
    13141 acggctgcgg aggcgctcat tacccatggg ttacccagcc gcgggctcgg taaggctgcc
    13201 ccgggacagg acccgggcca gcgcttccac cacctcggga gcgtagtcgc cggcggtggc
    13261 caggcgcagc tcctccagcg ccgtcaggac accgccgggg ccggcgtccc gcgccttctc
    13321 ctcgtaggcg ttcacgaccc gcacgatccg cgcggcgacc ggctgctccc ggcaggggtc
    13381 ggcctgccgc tccaccacca ccgcgaccgc cgcgtcgacg ccggtctggc ggacgacggc
    13441 cccgccgagc agcgcgatcc gccgctgttc ggcgacgggc aggtccgcgg tggcgcccgc
    13501 cgggaccggg tcgaccaggc tgagctggcc gatgtcgtgc atgagggccg cgtactcgag
    13561 gacggtcagc tccgcccccg acagccccag gtcccgtccg acggccaccc cgagcccggc
    13621 gacgcggcgg gcgtgcccgg ccggggtgta cccggcgatc tcggtggcgc gggccaggga
    13681 ggcgatggtc tgccggtagg tggcccggac ggccgcgtac cgccggtagg agagctgggc
    13741 gagcagcagg ggcacggaga agacggggag cgcccacagt cccgcgacgc tcaccgcgag
    13801 cgccatcacc gcgccggtcg cgcacaccgc cgacgtgatc ccgaccatgc cgcgcagctc
    13861 ttcgcgcagc agtggtccga agggccagcc ggtgcgcgcg tgtgcgggag ccacggcgag
    13921 cacggcgtcg cacagcgtgg tcagggccag cagcccgagc agcagcagcg cgtaggcggg
    13981 gccgctccag tcgtcgaaga cgccctggtt ggacagcggc cggaagcaga cggcggcgaa
    14041 gccgacggtg agcacgcgcc gcgccagggg gtggaggacg gggccgccgc cgcgggcgac
    14101 gtggggcacg ctgccgagca gtgaggcggc gagcacgacg gtgacggtct gcgcgacgcc
    14161 gtggtgcgcg ggctgcccgg ccacgtctcc gagcagcgcg tacgccagcg cgccggccgc
    14221 cccgagcgga gccgcctccc gggcctcggc gccggcccgc cgggtcagct cgccgagggc
    14281 gaccaggccg ccgaaggcga gcgccaccgg ccgctgcgcg ggctccgcga ccagtacgga
    14341 ggcgaggcac ccgagcgcga ggagcccggc accgccgggt acgagaagca gcgccgccgg
    14401 ggccgaggac ggggaccggc ccgtcgccgc cctccccggg gacgtgtccg ggcgcccccg
    14461 cccgtgccgg ggcggggaag gggtcggcac ccgcgacggg aagggcctca tggtctgccc
    14521 ccgtccacgc ggccaccacg ccccgcgccg cgccccacca cccggagctg ccaccccgcg
    14581 tccccgcccc ccgcgccgcg ccccaccacc cggagccgcc accccgcgtg ccccgtgctc
    14641 gtacggacgc cccgcaccgg aggctccgga ttcctcacgt cgcccccttg ccgacccggt
    14701 cccgcgcgcc cccgcccggc accgggtcgg cgcgggccgg tgtgccgtcc gccgtcaccg
    14761 ccgggcgcca gccgtggcgg ccgagggcgt ggaccagcgc ccgcaccatc cgcggatcga
    14821 actgcgcacc ggcacaccgc cgcagctcct ccagcgccgc cgcgacggga cgggccctgc
    14881 tgtaggagcg cgtggacgtc atcgcgtcga aggcgtcggc caccgcgacc acccgggccg
    14941 actcggggat ccggtcgccg accagtccgt aggggtagcc gctgccgtcc agccgttcgt
    15001 ggtggtggag cacggctgcg cgggcctctc cgaggaagcg gatgccgcgc accatctcgt
    15061 gcccgtactc gggatgcagt tcgatcaccc gccgctcctc gggcgtcagc ggaccgtcct
    15121 tgcgcagcag ccgggtgggc acaccgagct tgccgacgtc gtgcaggatc ccggcgaagc
    15181 ggagggtctc gacgcgttcg tcgtccatgc ccagctcgcg ggcgatcatc atggaggcct
    15241 gcccgacgcg ttcactgtgg ccgcgcgtgt agccgtcctt gatgtcgacg gcctgtacca
    15301 gcgcccggat ggtcgcctgg tgcgcggccc gctcgcggtg gtactgggcg aaggcccacc
    15361 acgccacgca catcggcagc agcacgagca gcgcggccac cggaccgtag gggctgcgcc
    15421 acaggaccgc catcatcagt ccggcgagcc cgtgcacggc gatcggcgcg agggacctgg
    15481 agaagagccc ccgccacgcc cggctcggcg gtacgcggtc ggcgagggtg aggatgccgc
    15541 cgtccaggag ggtgagcacc aggcagaacg cgaggacggc ggccccggcc ggcagaaggg
    15601 cgtacgggaa ggcgggttcg acgaccgcgt cccggccgcc gagccgccag tggacgcagg
    15661 cggcggccca cacggcgagg gtcagctgcg cggcccgcca gacgcgccgc aggccggacg
    15721 gccgccgggg caccggggac agcagcgccc cgggcagcgc cacgagcgcg gcggcgggcg
    15781 gcggcagcag gaaggcaccg gcgagcagga cggggtagca ggtcccgacg aaccgggacc
    15841 gcgcgaccag ctcggagccc gcgtacagcc cggccagcag cagcaccgcc caccagggcg
    15901 cgtgcaccga cggcagcggc cgcaggcaga gcagggcgac gagggcgacg cacacgacgt
    15961 acgcacgcgc gcgtgccggt accgcgtcca tgagccccct ccccggccac ccggtaaggc
    16021 tcggagccta ggacggcgac ggggaggccg cgggcagata agccgcggat tagcacgtac
    16081 gagtgacgcg gaacggcttg agcggctcgg tgcggctcag gactcctggg gtgccgacgg
    16141 cgtggccgtc acgtcgtgct cgggcacgga ctgcccggac cggatgaggt ccagccgtcc
    16201 catgaccttg gcgcgcaggt cacccggcac gtcgtcctgt ccgcagcagc gcttgaccag
    16261 cttcttcacg gcctgctcca gcccgtactt ctccaggcag ggcgagcact cctcgaagtg
    16321 gtgctcgaac ttcacgcagt ccgagtccgg catctccttg tcgaggaact cgtagagatg
    16381 atcgaggatt tcgctgcaat ccgtctcgtg cggctctccg cagctcatga ccccgagcct
    16441 ttcgcttcgt tcgactctcc ggcgccggcc gggaccaggc cgcggtcgcg ggcgtagtcc
    16501 tccagcatgc cgcgcagctg acggcgtcca cggtgcagcc gggacatcac cgtaccgatg
    16561 ggtgtcccca tgatgtccgc gatctccttg taggcaaagc cctcgacgtc cgccagatac
    16621 acggcgatac ggaattcctc ggggatcgcc tggagcgcct gcttcacgtc cgagtcgggc
    16681 aggtggtcga gcgcctgcga ctccgcggag cgcagacccg tcgacatgtg cgactcggca
    16741 cgggcgagct gccagtcctc gatctcctcg gccgcgctgc gctggggttc gcgctgcttc
    16801 ttgcggtacg agttgatgaa ggtgttcgtg aggatgcggt acagccacgc cttgaggttg
    16861 gtgccctcgc ggaactggtg gaaggacgcg tacgccttgg cgtaggtctc ctgcaccagg
    16921 tcctcggcgt cggccggatt acgcgtcatg cggagcgcgg ccgagtacat ctggtcgagg
    16981 aactccagcg cgtcccgctc gaagcgcgcg ctgcgctccg cggtcgactc cgcgcccgta
    17041 ccccggccct cgggctgctc cgcctggccg tgttcggtcc ctgcgtcggt cccagtgacc
    17101 ggacccacct cctccgatgt cgtcgtgaaa ccgaggccgg tctcactcga atcggaggat
    17161 agacgacctg cggtcgggga cgcgtgccga tccggtccgc ccgccgcccg aataggggcg
    17221 gtcttggcag cgtgcagcac ggtccagtcc aggtcggcgc ggctgctacg actcgggcag
    17281 aaggctgaac ccatgcggcg gacttcctct cctacggcgt cggtgctgat tctcagcaac
    17341 gtacgtccgg cacaacagtg accgcgcggc ggtcattccc gggcgttcag ccgagtgcgc
    17401 cgatccactt caggacgccg tcggtgatca cccgcagcgc ctgctcctgg gtggtctccg
    17461 cccgcttggg cacggcgaag ccgtggtcgc cgtacggcac ctcgatcagg tcgtaggttc
    17521 ccgcgggcgc ctcgggaaac tcctccggtc tgccgaaggg gtcgttgccg ccctggacca
    17581 cgagggtggg gacgcccgcc cggagcagtt cgtcggcgcg ggacttctcc ggcttgcccg
    17641 gcgggtgcag ggggaagctg agcgccagga cggcgtgtgc gcccagttca ccggcggtgc
    17701 ggcaggcgac gcgggcgccg gcgctgcggc cgcccgagat caccggcggg ccgggcgcgg
    17761 tgagcgcggg ccagacgccc cgccagccgg tgtccagggt cttcggcgcg ggcgccagct
    17821 tcttgccggc cacccgccag ggctgctcca cgagggcgac gctcaccccg tgggcgggca
    17881 gtgcggccgc cagcgccgtc aggtcgcgcg cctcgatgcc gccgccggcg ccgtggctca
    17941 gggcgaggac gaggcggggg tcccttgccc ggtgccaggt gatgcgggcg gagcccgcgt
    18001 ccgtctcgac cgcctctgtc acaacctctg tcgtatccgt cacgtcagaa gagtgtgccc
    18061 tcttccggtg cctccagctc cttgagcagc tccggcccgt tgttgcggac gttgctcacg
    18121 gccgtggaga cggggaaggc ccgcatcagc ccggtgggcg ggggcgtcag cagggaggtc
    18181 agcccgtccg ggtcggtgcg cgccgggtcg agccagtcgt cccagcggtc cggcgtgagc
    18241 atcagcggca tccgggggtg gatgtcggcc agggcgtacg ggccgtcggc cggggcgacc
    18301 gcgagcggcg tggtctcggc ctcggtggtg atcaccgagc acgtcaccca ccaggcctgc
    18361 gggtggtcgt ccggcagcgt ccggtcccgc cagaactcgt acagcccggc catggcgaac
    18421 acggagccgt cggcgggggt cacgaagtac ggctgcttgc ggggccgctt cttgcgcccc
    18481 tcgacctcca ggtcgcgctc ctgcttgccg gtgacccact cgtagtagcc gtcggcgggc
    18541 aggatgcagc gccgggtgct gaaggcgcgg cggtaggagg gcttctcgtg gacggtctcc
    18601 gcgcgggcgt tgatcatccg ggcgccgccc tcgggcgtct tggaccagga cgggaccagg
    18661 ccccacttca gcttccgcag ctggcgaacc ggcttcgggt cctcgacgtc tttcagggga
    18721 cggtccagaa cggcgtagac ctccttggtg ggcgccacgt tgtagtcggg ttccaagctc
    18781 tccttgggct cccacttctc gatctcgaag attcccgcga gatcctcggg tcgacgactc
    18841 gccgcatacc gtccgcacat acgtgccaca ctgccagacc ccgcgtttct acgaggagcc
    18901 ctccccgaac atggaccacc tcgcaacggc ctcgctcacc tctctgtggg acgaggtctc
    18961 cggcacccag cccgatcccg acctgtgggt ggtgatcgcg acgctggtgg ccgcgctcgc
    19021 cgtcgtcgcg acgcgcggat cgtggcggat agcgcgcaac gcgatcacca tcgcccacga
    19081 gggcggccac ggcctggtgg ccctgctgac cgggcgcacc ctgaccggga tcaccctgca
    19141 ctcggacacc agcgggctga cggtgagccg gggcaagccg cacggcgtcg ggatgatcct
    19201 gacggcggtc gccggctaca ccgctccccc gctgctcggc ctcggcggcg ccgcactgct
    19261 ggcggccggg cgcatcacgc tgctgctgtg gctggcgacg gcgctgctgg tggccctgct
    19321 ggtgatggtc cgcaacgcgt acggggtgct gacggtcgtg gtcaccggcg gcacgttcgt
    19381 cctggtgtcg tggctggccg ggccgcaggt gcaggcggcg ttcgcgtacg cggtggtctg
    19441 gttcctgctc ctgggcgggg tgcgcccggc gttcgagttg caggccaagc ggtcgcgggg
    19501 cggcgccggg gactcggacg cggaccagct ggcgcggctg acccacgcgc cggcgggggt
    19561 gtggttcttc ctcttccacg cggtgtcgct gtgctcactg atcggcgggg ggcgctggct
    19621 gctggagctg tgaggcccgg cgtgcgccca cccgcacccc atggctgcgc atatatgcac
    19681 ggcaagtgca ctgttgcggt ttcggtcagg tttcgccgct tttgatcaag atctccgatc
    19741 gccttcagcc attaaagtgg ggcccatgac cgtgaacccc gcgcacaccg ccctctggtc
    19801 cgccccgcac gcgagcggag ccgtcgacgc gaccgtccac gtgcccggat ccaagtcggt
    19861 caccaaccgc gccctggtcc tggccgccct cgcctccgag cccggctggc tgcgccgccc
    19921 gctgcgctcc cgcgacaccg tgctgatggc cgaggcgctg cgcgcgatgg gtgtcgagat
    19981 cgaggagggc gtgggcccgg acggcaccgg cgagttctgg cgggtcatcc cggcgggtct
    20041 gcgcggcccg gccacggtcg acgtcggcaa cgccggcacg gtgatgcggt tcctgccgcc
    20101 ggtcgccacg ctcgccgacg gcgccgtccg cttcgacggc gacccccggt cctacgagcg
    20161 tcccctgcac ggcgtgatcg acgcgctgcg cgtgctgggc gcccgtatcg acgacgacgg
    20221 gcgcggcgcc ctgccgctga ccgtgcaggg cggcggtgcc ctggagggcg ggccggtcga
    20281 gatcgacgcg tcgtcctcct cgcagttcgt cagcgccctg ctgctgtccg gaccgcgctt
    20341 caaccagggc gtcgaggtgc ggcacaccgg ctccgcgctg ccgtccatgc cgcacatccg
    20401 catgaccgtc gacatgctgc gcgcggtcgg cgcccaggtc gacacccccg agtccggcgg
    20461 cgagccgaac gtgtggcggg tgacgccggg cgcgctgctc ggccgggacc tgaccgtcga
    20521 gcccgacctg tccaacgccc agccgttcct ggcggcggcg ctggtgaccg gcggcaaggt
    20581 cgtgatcccc gactggccgt cccgcaccac ccagcccggc gaccggctgc gcgagatctt
    20641 caccgagatg ggcggttcct gcgaactgac ggacttcggg ctcgtgttca ccgggtcggg
    20701 cgcgatccgc ggcatcgacg tcgacctgag cgaggtcggc gagctgaccc cgggcatcgc
    20761 ggccgtcgcc gccctcgcgg actccccgtc gaccctgcgc ggcgtggccc acctgcggct
    20821 gcacgagacg gaccggctgg ccgcgctcac caaggagatc aacgaactcg gcggtgacgt
    20881 caccgagacc gccgacggcc tgcacatccg cccgcgccgg ctgcacggcg gggtcttcca
    20941 cacctacgag gaccaccgca tggccaccgc cggcgccgtc ctcggcctcg cggtcgaggg
    21001 ggtgcagatc gagaacgtcg cgaccaccgc caagacgctg cccgacttcc ccgacctgtg
    21061 gaccgggatg ctcggggcgt agggac
//
