LOCUS       NZ_WHZR01000001        21161 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. OM5714 A912_AS4_SC1_R2, whole genome shotgun
            sequence.
ACCESSION   NZ_WHZR01000001
VERSION     NZ_WHZR01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. OM5714
  ORGANISM  Streptomyces sp. OM5714
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7915160)
  AUTHORS   Samborskyy,M.
  TITLE     Whole Genome Sequence of the phthoxazolin producer Streptomyces sp.
            OM5714
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7915160)
  AUTHORS   Samborskyy,M., Dickens,S. and Scott,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2019) Biochemistry, DNA Sequencing Facility,
            University of Cambridge, 80 Tennis Court Road, Cambridge,
            Cambridgeshire CB2 1GA, United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: OCT-2017
            Assembly Method                   :: Newbler v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 102.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010993835.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:48:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,820
            CDSs (total)                      :: 7,730
            Genes (coding)                    :: 7,557
            CDSs (with protein)               :: 7,557
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 7, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 7, 5 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 58 of 173
            Pseudo Genes (incomplete)         :: 139 of 173
            Pseudo Genes (internal stop)      :: 18 of 173
            Pseudo Genes (multiple problems)  :: 36 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:03:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2679806
            Orig. end                         :: 2700967
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WHZR01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21161
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="16"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21161
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21161
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11161](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11161)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(16..981)
                     /locus_tag="STPH1_RS11400"
                     /old_locus_tag="STPH1_2278"
     CDS             complement(16..981)
                     /NRPS_PKS="Domain: PKS_ER (20-318). E-value: 1.3e-33.
                     Score: 108.4. Matches aSDomain:
                     nrpspksdomains_STPH1_RS11400_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571395.1"
                     /locus_tag="STPH1_RS11400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2278"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_153177997.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.2e-20, bitscore:
                     70.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAVYAARIDRDQPLAGLELGELPAPEARPGWSVVDVRAASLNHH
                     DLWSLRGVGLPEDRLPMILGCDAAGVDADGNEVVLHSVIGQTGHGVGPKEPRSILTERY
                     PGTFAEQVAVPTWNILPKPRELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAG
                     GGVATAAIVLGKAAGLRVFATSRDEAKRKRALELGAVEAVETGARLPQRVDAVIETVGA
                     ATWSHSIKSLRPGGTLVISGATSGDRPSHAELTRIFFLELKVVGSTMGSKDELEDLLSF
                     CAATGVRPVIDEVLPMDRAREGFERMASGGQFGKIVLSNS"
     aSDomain        complement(28..921)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_STPH1_RS11400_PKS_ER.1"
                     /evalue="1.30E-33"
                     /label="STPH1_RS11400_PKS_ER.1"
                     /locus_tag="STPH1_RS11400"
                     /protein_end="318"
                     /protein_start="20"
                     /score="108.4"
                     /tool="antismash"
                     /translation="GELPAPEARPGWSVVDVRAASLNHHDLWSLRGVGLPEDRLPMILG
                     CDAAGVDADGNEVVLHSVIGQTGHGVGPKEPRSILTERYPGTFAEQVAVPTWNILPKPR
                     ELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIVLGKAAGLRVFA
                     TSRDEAKRKRALELGAVEAVETGARLPQRVDAVIETVGAATWSHSIKSLRPGGTLVISG
                     ATSGDRPSHAELTRIFFLELKVVGSTMGSKDELEDLLSFCAATGVRPVIDEVLPMDRAR
                     EGFERMASGGQFGKIVL"
     CDS_motif       complement(469..522)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STPH1_RS11400_0002"
                     /evalue="6.00E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="STPH1_RS11400"
                     /protein_end="171"
                     /protein_start="153"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GDSVLVQGAGGGVATAAI"
     CDS_motif       complement(553..591)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_STPH1_RS11400_0001"
                     /evalue="5.60E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="STPH1_RS11400"
                     /protein_end="143"
                     /protein_start="130"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AACLPTAWLTAYR"
     gene            complement(1287..2516)
                     /locus_tag="STPH1_RS11405"
                     /old_locus_tag="STPH1_2279"
     CDS             complement(1287..2516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997977.1"
                     /locus_tag="STPH1_RS11405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2279"
                     /product="NADP-dependent malic enzyme"
                     /protein_id="WP_153177998.1"
                     /transl_table=11
                     /translation="MAAEIVNPRSDSDASAEQETGAEPLDSFDPAFALHRGGKMAVQAT
                     VPVRDKEDLSLAYTPGVAKVCSAIAEQPDLVHDYTWKSSVVAVVTDGTAVLGLGDIGPE
                     ASLPVMEGKAILFKQFGGVDAVPIALNCTDADEIVETVVRLAPSFGGVNLEDISAPRCF
                     EIERKLQERLDIPVFHDDQHGTAVVTLAALRNAARLSGRTLGELRAVISGAGAAGVAIA
                     KMLVEAGIGDVAVADRKGVVSADRDDLTPVKRELAGFTNKAGLSGSLDAALSGADVFIG
                     VSGGTVPEPAVASMAKGAFVFAMANPNPEVHPEVARKYAAVVATGRSDFPNQINNVLAF
                     PGIFAGALQVRASRITEGMKLAAAEALASVVGDDLAADYVIPSPFDERVAPAVTAAVAA
                     AARAEGVARR"
     misc_feature    2545..2560
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(2757..2767)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(2856..2870)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.43"
                     /tool="antismash"
     gene            3155..4117
                     /locus_tag="STPH1_RS11410"
                     /old_locus_tag="STPH1_2281"
     CDS             3155..4117
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973710.1"
                     /locus_tag="STPH1_RS11410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2281"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_164383272.1"
                     /transl_table=11
                     /translation="MTARSTRRTTAAHSRLAAVGAIAVAGALLLTGCGDQTENGDSGGS
                     DNQSSGGAPLADKLPQSIRDKGTIKVGSDIAYAPVEFKDDSGKTVGIDPDLADALGKQL
                     GVKFEFENGTFDTLITGLRSKRYDIAMSAMTDTKDRQEGIDADTGKKVGQGVDFVDYFT
                     AGVSIYTKKGDDQGIKTWSDLCGKKLVLQRGTVSEDLAKAENEKCPAGKKISMEAFDND
                     QQAQTRLRAGGADAGSSDFPVAAYAVKTSGGGKDFQIVGEQVEAAPYGIAVAKDNTQLR
                     DALKAALDAVIANGEYKKIMDKWGVAEGAVTEAAVNGGK"
     gene            4148..5098
                     /locus_tag="STPH1_RS11415"
                     /old_locus_tag="STPH1_2282"
     CDS             4148..5098
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973711.1"
                     /locus_tag="STPH1_RS11415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2282"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_153178000.1"
                     /transl_table=11
                     /translation="MTVDIDKTAGGPAGTPPTPPEAIKAIPVRHYGRYVSAVVAIALLA
                     AVVYAFSQGKINWGAIPDYFFDDRVLTGMGKTLLITVLAMLIGVVGGILLAVMRLSKNP
                     VTSSIAWFYIWFFRGTPVLVQLVVWFNLGLVFEYINLGPFYRDEWSDFMTPFLTALLGL
                     GLNEAAYMAEICRAGLLAVDEGQTEAAHALGMSHAKTLRRIVVPQAMRVIVPPTGNEVI
                     NMLKTTSLVSVVQYAELFRVAQDIGQTSGAPAEMLFLAAAWYLLLTSVFSVGQYYLERY
                     YARGSSRSLPPTPMQKIRANLFSLSNRSSTTGGAA"
     gene            5095..5856
                     /locus_tag="STPH1_RS11420"
                     /old_locus_tag="STPH1_2283"
     CDS             5095..5856
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="STPH1_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2283"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_054099059.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGAVEVLKGIDLEVKQGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPH
                     MTAVENVMEAPVQVKGMSRSQARDRARGLLERVGLGDKAGNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFM
                     DNGVVVESGNPRDVLTDPQHDRTKAFLSKVL"
     gene            complement(5919..6722)
                     /locus_tag="STPH1_RS11425"
                     /old_locus_tag="STPH1_2284"
     CDS             complement(5919..6722)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030136.1"
                     /locus_tag="STPH1_RS11425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2284"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_164383273.1"
                     /transl_table=11
                     /translation="MTDADATTTTATTISTTTAAGADWQAWQQSWDRQQEWYMPDREER
                     FQIMLDMVEALVGPAPRVLDLACGTGTITARLLARFPQATSTGVDLDPALLAIAEGTFA
                     GDERVDLVTADLKDPDWPARLPHDTYDAVLTATALHWLHAEPLADLYGRVAELVRDGGL
                     FMNADHMIDDTTPRINAAERAQRHTRMDAAKDQGALDWAQWWQLAAKDPVLAGPTARRF
                     EIYGEHADGDMPSAAWHARVLREKGFGEARPVWCSPSDTLLLALK"
     misc_feature    complement(6815..6830)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            6823..7452
                     /locus_tag="STPH1_RS11430"
                     /old_locus_tag="STPH1_2285"
     CDS             6823..7452
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="STPH1_RS11430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2285"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_007444606.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPSRGQDALTSVEAVRELFGANQSAARR
                     ASDADVTRFRSVRGRLRAVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDHRAEDGS
                     PLWHMHLADHPSNATAGFAAIAAMGLAFHLTEYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSAGTGLTADSAQRTAANGER"
     gene            complement(7356..7793)
                     /gene="sodX"
                     /locus_tag="STPH1_RS11435"
                     /old_locus_tag="STPH1_2286"
     CDS             complement(7356..7793)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="STPH1_RS11435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2286"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_007444623.1"
                     /transl_table=11
                     /translation="MPEQLSQETERARGALPFGPAEVTGPSMVPTLHHGDVLLVHWGAR
                     VRPGDVVVLRHPFQQDLLVVKRAAERRGTGWWVLGDNAFAGGDSTDYGVVPQDLVLGRV
                     RFRYRPPRPGQRSPFAAVRWALSAVRPVPADRSASRRLRAR"
     gene            7939..8334
                     /gene="sodN"
                     /locus_tag="STPH1_RS11440"
                     /old_locus_tag="STPH1_2287"
     CDS             7939..8334
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="STPH1_RS11440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2287"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_003973716.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVTVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGN
                     DDPHFQTRATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     SKDPATGQKALDYIAQIDKIFWETKKA"
     gene            complement(8442..8663)
                     /locus_tag="STPH1_RS39470"
     CDS             complement(8442..8663)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973717.1"
                     /locus_tag="STPH1_RS39470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_164383274.1"
                     /transl_table=11
                     /translation="MDSDTYVCPVCGQPVEAVARRHKTLGAWVPTWGPGPCHNPECAAG
                     PEPDTRTAGTRTRPGTERHRRGATAEKP"
     misc_feature    8617..8632
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            complement(8690..9057)
                     /locus_tag="STPH1_RS11450"
                     /pseudo=""
     CDS             complement(8690..9057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="STPH1_RS11450"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRKLTYFIACSIDGFIGGPDGDASFMYPFVDEASRSSRRTWSAGS
                     GS"
     misc_feature    9115..9133
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.31"
                     /tool="antismash"
     gene            complement(9135..9761)
                     /locus_tag="STPH1_RS11455"
                     /old_locus_tag="STPH1_2290"
     CDS             complement(9135..9761)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444621.1"
                     /locus_tag="STPH1_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2290"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_164383275.1"
                     /transl_table=11
                     /translation="MGVAIRTAGADDRDLVVRLLDEAFQDDPVSSWVFPGEEYRRRTHH
                     RLMAAFADAVFADGRIDLTEDGAACALWLPVPADEYPGAEPDSGSGADVEDVPARIREA
                     VDPDNERVEAIARLTEGIHPTGRAHAYLWMIGVVPGRQGEGLGTALIESVLDRCDREGL
                     PAYLEASSARGKALYERLGFEFTGRAVDLPEGPCMWPMWREPRTR"
     gene            complement(10001..11161)
                     /locus_tag="STPH1_RS11460"
                     /old_locus_tag="STPH1_2291"
     CDS             complement(10001..11161)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973720.1"
                     /locus_tag="STPH1_RS11460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2291"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_164383276.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-60, bitscore:
                     203.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEIRRGATATRRSTGTPETHGFIGTQRDEEPAESSGGQGPVMAE
                     GHEAATLLRESRASVDPELRSAIASLPDAMRRIALYHFGWQHADGTPATGNAGKAIRPA
                     LVLTAATALGGPAARAAAGRAAAAVELAHNFTLLHDDVMDRDVTRRHRPTAWAVFGVAD
                     AILAGDALQALALRLLAADPHPASAAAAARLSDCVMELCEGQHVDTALEGRPPGEVTLD
                     ETLAMAEAKTGALLGCACALGALYAGAAPEDVDALDAFGREAGLAFQLIDDVIGIWGDP
                     RHTGKPAGADLAARKKSLPVVAALTSGTPAAAELAELYAAPYDEDKEDLERTALVVERA
                     GGRDWAQAQAADRMARAMQELARAVPAPEAAGGLLALAEFVTRRST"
     misc_feature    11189..11204
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.47"
                     /tool="antismash"
     gene            complement(11247..12653)
                     /locus_tag="STPH1_RS11465"
                     /old_locus_tag="STPH1_2292"
     CDS             complement(11247..12653)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="STPH1_RS11465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2292"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_153178013.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQTRPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDIQGGTYRVNRRMTFAVGDGRVTFVKTGDRVEVIPAELGELPALRSYEDDEVL
                     SELAQRCEQREFGPGEVIASFGGRTDEVYLLAHGKIEKIGTGPYGDDAVLGVLADGAYF
                     GDQALLDGDAIWEYTARTVTACTVLVLPRQEVEQVAERADSLREHLEQRRAVPQQRTNK
                     HGEKEIDLAAGHSGEPDIPHTFVDYEARPREYELSVAQTVLRIHSRVADLYNQPMNQTE
                     QQIRLTVEALKERQEHELINNREFGLLHNCEYDQRIQPHDGVPGPDDLDELLSRRRGTK
                     LLLAHPRAIAAIGREFNRRGLVPETIDVAGNRIPTWRGVPIYPCNKIPVTEARTSSIIA
                     MRTGEQDQGVIGLRATGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     misc_feature    complement(12721..12734)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.09"
                     /tool="antismash"
     gene            12992..13570
                     /locus_tag="STPH1_RS11470"
                     /old_locus_tag="STPH1_2293"
     CDS             12992..13570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030135.1"
                     /locus_tag="STPH1_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2293"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_164386326.1"
                     /transl_table=11
                     /translation="MSASSFLKALKAEGLTVVEVGDWRDHNRDHKGPWGPVHGVLLHHT
                     VTRGSARTVEICRKGHEDLPGPLCHGVITKDGTVHLVGYGRANHAGPGDDDVLRAVVAE
                     KAPPPDNEADTDGNRHFYGFECENLGDGDDPWPAAQLDAIERAAAAVCRHHGWNERSVL
                     GHLEWQPGKVDPRGFTMASMRERIRDRLK"
     gene            13627..14535
                     /locus_tag="STPH1_RS11475"
                     /old_locus_tag="STPH1_2294"
     CDS             13627..14535
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973723.1"
                     /locus_tag="STPH1_RS11475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2294"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_164383277.1"
                     /sec_met_domain="PALP (E-value: 8.5e-18, bitscore: 63.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTDSRGLAALRPRLPSPLQEVADDRFERRGVRLLLKRDDLIHP
                     DLVGNKWRKLAPNLAAADGRTVVTFGGAYSNHLRAAAAAGRLLGLPTVGVVRGQELAGL
                     PLNPSLARCAADGMRLHFVDRSTYRRKSEPETLAALLRAVGAEDAVVVPEGGSSPQAVR
                     GCRALGEELGEHADVAAVACGTGGTLAGLAAGLPAGRRALGTAVLRGGFLERDIRRLQE
                     HAFGGPRGTWSLEERFHHGGYARTTPGLDAFAADFEDRHGLAVERVYVAKMLYALLALA
                     EEGAFPRGTTLAAVVTGRPFP"
     gene            complement(14567..16159)
                     /locus_tag="STPH1_RS11480"
                     /old_locus_tag="STPH1_2295"
     CDS             complement(14567..16159)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973724.1"
                     /locus_tag="STPH1_RS11480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2295"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_164383278.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAVAGAGRRVPVPVPLLLVAAGLAVSYVPGVP
                     DYTLDPHIVLPLLLPPLLYTAATDSSYLDLRAQARPVALLSVGYVLFATFVVGGAAYFI
                     VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRVTTILQGESLVNDATAITAFKVA
                     LAAAVGEGATWAGGIGEFLIAAVGGVGVGLVLMVPLHWLRTHLTEALLQNTLSLLIPFV
                     AYAVAEQVHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGEYEGAEAAGYALAVFLVVAVARFVWVYPATFLPRLSARVRAREGELSWK
                     GPFVIGWAGMRGVVSLAIAFSIPLTVHGGEPFPERNLILFLTFTTVIGTLVVQGVSLPP
                     LIRLLKFPAHDARAETLAEANAQAQASRVADERLDALLADERNALPVPLADRLRTVLER
                     RRNAVWERLGQVNPVTGETVDDTYRRLSREMIGAEREVFVRLRDGRYIDDEMLRTLLRR
                     LDLEEAAAYRETT"
     gene            16221..16481
                     /locus_tag="STPH1_RS11485"
                     /old_locus_tag="STPH1_2296"
     CDS             16221..16481
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="STPH1_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2296"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_007444602.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPEPCGETCPECLAEGTDPVQLRLCLSCGHVG
                     CCDSSPRRHATAHHAKTGHPVMRTFEPGESWRWCFVDHVLV"
     misc_feature    complement(16590..16603)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            16732..17145
                     /locus_tag="STPH1_RS11490"
                     /old_locus_tag="STPH1_2297"
     CDS             16732..17145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985353.1"
                     /locus_tag="STPH1_RS11490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2297"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_003973726.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVSISLYKQRGAGPGPT"
     gene            17163..18227
                     /locus_tag="STPH1_RS11495"
                     /old_locus_tag="STPH1_2298"
     CDS             17163..18227
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="STPH1_RS11495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2298"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_228126109.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPAEGTRSPNEARRTADGIDGIPEQARPHPEDETS
                     PEAVAPVDGQRTGDTPVPPVRPEERARERATGGTMSEHERHSDGHAPGARGTQGTRHDP
                     HDRSGARLLFAELRTLTKDSPEYAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVA
                     TIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLALTTAT
                     AELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLG
                     AEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLA
                     RTLAQLREKLLVEE"
     gene            complement(18266..18718)
                     /locus_tag="STPH1_RS11500"
                     /old_locus_tag="STPH1_2299"
     CDS             complement(18266..18718)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444616.1"
                     /locus_tag="STPH1_RS11500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2299"
                     /product="hypothetical protein"
                     /protein_id="WP_153178017.1"
                     /transl_table=11
                     /translation="MSSEQTPDPASPAAEEAEPRPVRVTAAAAIAALEGLALVVGGAWM
                     LVEGLTGHPDDRTAAVTGGITLIVLALLPLLAARGLLRLRGWSRGPAVITQIVSLPVAY
                     NMAGADGLAVPAGVVLGVAALTALYLLINPETTLALGIRGPGNAGK"
     gene            18852..19820
                     /locus_tag="STPH1_RS11505"
                     /old_locus_tag="STPH1_2300"
     CDS             18852..19820
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="STPH1_RS11505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2300"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_153178018.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAAQSDDVDLVVALGGDGTVNEVVNGLLHAGPDPDHLPGLAVVPGGSTNVFARALG
                     LPNHAVEATGALLDALREGSERTVGLGLASGTPGTEDEAVPARWFTFNAGLGFDAGVVG
                     RVEQHRERGKKSTHALYVRQVVRQLIGEPHRRSGTITLERPGEDPVTDLVLSIVSNTCP
                     WTFLGNRPIYASPQASFDTALDVFGLKRLSTAAVARYGTQLLTSSPERGPRGRHAVTLH
                     DLTEFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(19905..19919)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.74"
                     /tool="antismash"
     misc_feature    complement(19910..19919)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20081..20096)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20084..20095
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20141..20398
                     /locus_tag="STPH1_RS11510"
                     /old_locus_tag="STPH1_2301"
     CDS             20141..20398
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="STPH1_RS11510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="STPH1_2301"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003973730.1"
                     /transl_table=11
                     /translation="MDWRHRAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
ORIGIN
        1 ccagaagtaa ggacctcagg agttgctgag cacgatcttg ccgaactgcc ctccggaagc
       61 catccgctcg aacccctcgc gggcccggtc catcgggagc acctcgtcga tgacgggccg
      121 cacaccggtg gcggcgcaga aggacagcag gtcctccagc tcgtccttgg aacccatcgt
      181 ggagccgacg accttgagct ccaggaagaa gatccgggtc agttcggcgt gggagggccg
      241 gtcgccgctg gtggccccgg agatgaccag cgtgccgccg ggccgcagcg acttgatgga
      301 gtgcgaccag gtcgcggcgc ccacggtctc gatgacggcg tcgacccgct gcggcagccg
      361 cgccccggtc tcgacggcct ccacggcacc cagctccagg gcccgcttgc gcttggcctc
      421 gtcccggctg gtggcgaaga cccgcagccc cgccgccttg ccgagcacga tcgcggccgt
      481 ggcgacaccg ccgccggcgc cctgcaccag cacggagtca ccgggacgca ccccggcgtt
      541 ggtgaacagc atccggtacg ccgtcagcca ggcggtcggc aggcaggcgg cctcctcgaa
      601 ggaaagctcc ctgggcttgg gcaggatgtt ccaggttggc acggcgacct gctcggcgaa
      661 cgtccccggg tagcgctcgg tgaggatgga gcggggctcc ttgggaccga ccccgtggcc
      721 ggtctggccg atcacggagt gcaggacgac ctcgttgccg tccgcgtcga ccccggcggc
      781 gtcgcagccg aggatcatcg gcagccggtc ctcggggagg ccgacaccgc gcagggacca
      841 caggtcgtgg tggttgaggg aggcggccct gacatcgacg acactccagc cggggcgggc
      901 ctcgggagcc ggaagctctc ccaactccag gccggccagc ggctggtcgc ggtcgattcg
      961 ggcggcgtag acagcgaaca tgaccttgac gataggttcc ccaccgccca accgaaacca
     1021 cacacccatg tgacacaccc cctcttgcgc ccgccgccgt agctgcgggc agtcgtgccc
     1081 cgtccccccc agctgcgggc agtcgtgccg ctggggcggc acgggtgggc gcagcggcac
     1141 ccggccagcg ccggccaccg ccccaccccc gcccagccca agcgcaccgg cacccgcacc
     1201 cgcacccgca cctgcacccc aaacaagcga gcggccccgc ccaccaggga cgagaccgct
     1261 caccacaccc gcagaggttc acaccgtcac cggcgcgcaa ccccctccgc ccgagccgcc
     1321 gcggccaccg ccgccgtcac ggccggcgcc acccgctcgt cgaagggcga cggaatgacg
     1381 tagtccgcgg cgaggtcgtc ccccaccacg gacgccagcg cctcggccgc cgcgagcttc
     1441 atgccctcgg tgatccgcga cgcccgcacc tggagagcgc ccgcgaagat gcccgggaac
     1501 gccagcacgt tgttgatctg gttcgggaag tccgagcgcc ccgtcgccac gaccgccgcg
     1561 tacttgcggg cgacctccgg atgcacctcg gggttcgggt tggccatcgc gaagacgaac
     1621 gcacccttcg ccatcgaggc caccgccggc tccggcaccg taccgccgga gaccccgatg
     1681 aagacgtcgg cgcccgacag ggccgcgtcc agcgaacccg acagcccggc cttgttggtg
     1741 aagccggcca gctcccgctt caccggcgtc aggtcgtccc ggtcggccga gacgacgccc
     1801 ttgcggtcgg cgaccgcgac gtccccgatg ccggcctcca ccagcatctt ggcgatggcg
     1861 accccggccg cgcccgcgcc cgagatcacc gcccgcagtt cgcccagcgt ccgcccgctc
     1921 agccgcgccg cgttccgcag ggccgccagc gtcacgacgg ccgtgccgtg ctggtcgtcg
     1981 tggaagaccg ggatgtccag gcgctcctgg agcttgcgct cgatctcgaa gcaccgcggc
     2041 gccgagatgt cctcgaggtt gacgccgccg aaggagggcg cgagccggac cacggtctcg
     2101 acgatctcgt cggcgtcggt gcagttcagg gcgatcggga ccgcgtccac gccgccgaac
     2161 tgcttgaaga ggatggcctt gccctccatc acgggaaggg aggcctcggg cccgatgtcc
     2221 ccgagcccca gcaccgccgt cccgtccgtc acgaccgcga cgaccgacga cttccaggtg
     2281 tagtcgtgca cgaggtcggg ctgctcggcg atcgcgctgc acactttcgc gacgccgggc
     2341 gtgtacgcca gggacaggtc ttccttgtcg cggaccggca cggtggcctg cacggccatc
     2401 ttgccgccgc ggtgcagcgc gaacgcgggg tcgaaggagt cgagcggctc ggcgcccgtc
     2461 tcctgctccg cactggcgtc gctgtcgctg cgaggattga cgatctccgc tgccactttg
     2521 tcttacccct taagagttca tggattgagg gtttgtccac tcctggtgag gaatgggcgg
     2581 gcaccgcaca gggagatggc tgtctgggcc acgaggcccc tgcgcgacgg gcgcgccgca
     2641 cacgcgccct gagcccctga tgaggggtgt aaagaacctt cttacccgac ggacggcccc
     2701 cgcgacgagt ccgataagcg caagctcaca tgccggaccc cgcgccccgc atgtcggtga
     2761 catggctcat agccggggtt ccggacaacc tcccggcacc ccttgacata cccgcgaact
     2821 ccaccttcga cggcccggct cacccacgat ccagcttcgg ataacgagaa attccgtaga
     2881 tcttccggcc ggaagggcag attcccgcaa aggttcggtc gtgatgtacc gacctggtgc
     2941 ggttcggggg gtgacccgtt atccgatttt gacatggcgt cccccctgaa tggccgagtc
     3001 cgaatggcaa gatgccgtaa tcgcacgagg tcgcggcgct cgaagatgtg tgcccgcgac
     3061 gacccgcggc gccgtccggc ccccggccgg cgtccgtccc accggaactc caccgtcccc
     3121 atcgggtact ccctcatccg ccggaggaac caccatgacc gcacgctcca cccgtcgtac
     3181 gaccgccgcg cactcccggc tagcagcggt cggtgcgatc gcggtcgcag gcgccctgct
     3241 gctcaccgga tgcggtgacc agaccgagaa cggcgactcc ggcggcagcg acaaccagtc
     3301 ctcgggcggc gccccgctgg ccgacaagct gccccagtcg atccgcgaca agggcaccat
     3361 caaggtcggc tccgacatcg cctacgcacc ggtcgagttc aaggacgact ccggcaagac
     3421 cgtcggtatc gaccccgacc tcgcggacgc cctgggcaag cagctcgggg tgaagttcga
     3481 gttcgagaac ggcaccttcg acaccctgat caccggcctg cgctccaagc ggtacgacat
     3541 cgccatgtcc gcgatgaccg acaccaagga ccgccaggag ggcatcgacg ccgacaccgg
     3601 caagaaggtc ggccagggcg tcgacttcgt cgactacttc accgccggtg tctcgatcta
     3661 caccaagaag ggcgacgacc agggcatcaa gacctggtcc gacctgtgcg gcaagaagct
     3721 cgtgctccag cgcggcacgg tctccgagga cctcgccaag gccgagaacg agaagtgccc
     3781 ggccggcaag aagatctcca tggaggcctt cgacaacgac cagcaggccc agacccgcct
     3841 gcgcgcgggc ggcgcggacg ccggttcctc cgacttcccg gtcgcggcct acgcggtgaa
     3901 gacctccggc ggcggcaagg acttccagat cgtcggcgag caggtcgagg ccgccccgta
     3961 cggcatcgcg gtcgccaagg acaacacgca gctgcgcgac gccctcaagg cggcgctgga
     4021 cgcggtgatc gccaacggcg agtacaagaa gatcatggac aagtggggcg tggcggaagg
     4081 cgccgtcacc gaggccgccg tcaacggcgg caagtgaccg cgcggcgggc gctgaaaggc
     4141 aacatccgtg actgttgaca tcgacaagac ggcgggcggc ccggccggca ccccgccgac
     4201 cccgcccgag gccatcaagg ccatcccggt ccggcactac gggcggtacg tctccgcggt
     4261 cgtcgcgatc gcgctgctgg ccgcggtcgt gtacgcgttc tcccagggca agatcaactg
     4321 gggcgcgatc ccggactact tcttcgacga ccgtgtcctg accggcatgg gcaagaccct
     4381 cctgatcacc gtcctcgcga tgctgatcgg cgtcgtcggc ggcatcctgc tcgccgtgat
     4441 gcggctgtcg aagaacccgg tgacctcgtc catcgcgtgg ttctacatct ggttcttccg
     4501 cggcacaccg gtcctggtgc agctggtcgt ctggttcaac ctgggtctgg tcttcgagta
     4561 catcaacctc ggcccgttct accgcgacga gtggtcggac ttcatgacgc cgttcctgac
     4621 ggcgctgctc ggcctcggtc tgaacgaggc ggcgtacatg gcggagatct gccgcgccgg
     4681 tctgctcgcg gtcgacgagg gccagaccga ggcggcgcac gcgctcggca tgagccacgc
     4741 caagacgctg cgccggatcg tggtcccgca ggcgatgcgc gtgatcgtgc cgccgacggg
     4801 caacgaggtc atcaacatgc tgaagacgac ctccctggtg tcggtcgtcc agtacgccga
     4861 gttgttcaga gtcgcccagg acatcggcca gacctcgggc gcaccggccg agatgctgtt
     4921 cctcgcggcg gcctggtacc tgctgctgac ctcggtcttc agcgtcggcc agtactacct
     4981 ggagcggtac tacgcccgcg gctccagccg cagtctgccg ccgaccccga tgcagaagat
     5041 cagggcgaac ctgttctccc tgtcgaaccg ctccagcacg accggaggtg cggcatgacc
     5101 gccatggtca aggcagaagg cgtccacaag tccttcggtg ccgtcgaggt tctcaagggc
     5161 atcgacctgg aggtcaagca gggcgaggtg ttctgcctca tcggcccctc cggctccggc
     5221 aagtcgacgt tcctgcgctg catcaaccac ctggagaaga tcaacgccgg gcgtctctac
     5281 gtcgacggcg agctggtcgg ctaccgccag aagggtgaca agctctacga gctgaaggac
     5341 agcgaggtcg ccctcaagcg ccgggacatc ggcatggtct tccagcgctt caacctgttc
     5401 ccgcacatga cggccgtgga gaacgtcatg gaggcaccgg tccaggtcaa gggcatgagc
     5461 aggagccagg ccagggaccg cgcgcgcgga cttctggagc gggtgggcct gggcgacaag
     5521 gccggcaact acccctcgca gctctccggg ggccagcagc agcgcgtggc catcgcgcgg
     5581 gccctggcca tggacccgaa gctgatgctg ttcgacgagc cgacctcggc gctcgacccc
     5641 gagctggtgg gcgacgtcct cgacgtcatg cgggacctcg cggagtccgg catgacgatg
     5701 gtcgtcgtca cccacgagat gggcttcgcc cgcgaggtcg gcgacagcct cgtcttcatg
     5761 gacaacggcg tggtcgtcga gtcgggcaac ccgcgcgacg tcctgaccga tccgcagcac
     5821 gaccggacga aggcgttcct gtccaaggtc ctctgaccgt ccgcacgacc acgccgaggg
     5881 gcggtacgga tctccgtacc gcccctcggc gtgtggtcct acttgagcgc cagcagcagg
     5941 gtgtccgacg gcgagcacca caccgggcgc gcctcgccga agcccttctc gcgcagcacg
     6001 cgcgcgtgcc acgccgccga gggcatgtcg ccgtccgcgt gttcgccgta gatctcgaaa
     6061 cgccgtgcgg tgggtccggc gagcaccggg tccttggcgg cgagctgcca ccactgcgcc
     6121 cagtccagcg cgccctggtc cttggcggcg tccatgcgcg tgtgccgctg cgcgcgctcg
     6181 gccgcgttga tccggggcgt cgtgtcgtcg atcatgtggt ccgcgttcat gaagagacca
     6241 ccgtcgcgga ccagctccgc gacccggccg tagagatccg cgaggggttc ggcgtgcaac
     6301 cagtgcaggg ccgtggcggt cagcacggcg tcgtacgtgt cgtgcggcag ccgggccggc
     6361 cagtcggggt ccttgaggtc ggcggtcacg aggtcgaccc gctcgtcgcc cgcgaaggtg
     6421 ccctcggcga tggcgaggag cgcggggtcg aggtccacgc ccgtgctcgt ggcctgcggg
     6481 aaccgggcga gcagccgggc cgtgatggtg ccggtgccgc aggccaggtc gagcacgcgc
     6541 ggcgcggggc ccacgagcgc ctcgaccatg tcgagcatga tctggaaccg ttcctcgcgg
     6601 tccggcatgt accactcctg ctgccggtcc cagctctgct gccacgcctg ccagtcggct
     6661 cccgccgcgg tggtcgtgct gatcgtggtg gccgtggtcg tggtggcgtc cgcgtccgtc
     6721 atcgagcccc tccgtgcctg cgtcactgta ataccctgga agcacagtca gccattacct
     6781 gaccgcaggc acgaccctag agccccttcg taaggactac aagtggaact ggcctattac
     6841 tcggattacg ccgtacgtct cgtcaacacc gaggaaccgt cgcggggtca ggatgcactg
     6901 acctcggtgg aggccgtccg agagctcttc ggcgccaacc agtccgcggc ccggcgcgcg
     6961 tccgacgccg acgtgacgcg gttccgctcg gtccggggcc ggctgcgcgc ggtcttcgag
     7021 gcggccgacg gcggcgacga gaccctcgcc gtggacctgc tgaactcgct gctcctggag
     7081 ttcccggtga gcccgcagat ctccggccac gaccaccgcg cggaggacgg cagcccgctg
     7141 tggcacatgc acctggccga ccacccctcc aacgcgaccg ccggtttcgc ggccatcgcg
     7201 gcgatgggcc tggccttcca cctcaccgag tacggcgtcg accggctggg cctgtgcgag
     7261 gctgccccct gccgcaacgc ctacctggac acctccacca accgatcccg ccgctactgc
     7321 tccgaccgct gcgccacccg cgccaacgtg gcggcctacc gcgcccgcaa gcgcctggag
     7381 gcggaccggt cggccggcac cggcctgacc gccgacagcg cccagcggac cgcggcgaac
     7441 ggcgaacgct gacccggccg cggcggccgg tacctgaacc ggacccggcc cagtacgagg
     7501 tcctgcggga ccaccccgta gtcggtgctg tccccgcccg cgaacgcgtt gtccccgagc
     7561 acccaccagc cggtcccgcg ccgttcggcc gcccgcttga ccacgagcag gtcctgctgg
     7621 aagggatgcc gcagtacgac cacgtcaccc ggccggaccc gcgcccccca gtgcacgagc
     7681 agcacgtcac cgtggtgcag cgtgggcacc atcgacggcc cggtcacctc ggccgggccg
     7741 aagggcagcg cccctctggc gcgctcggtc tcctgcgaca gttgctccgg catcacccgg
     7801 cacctccccg gtctttcctc caccagtctc agtctcaccc gggacttttg tcctaagccc
     7861 acgggggcac ccgcgaaaac gggtctccca gggagtaatg tcccccctga gaagacgatc
     7921 acgaggaagg aacgcttcat gctttcccgc ctgtttgccc ccaaggtcac ggtcagcgcc
     7981 cactgcgacc tgccctgcgg cgtgtacgac ccggcccagg cccgcatcga ggcggagtcg
     8041 gtgaaggccg tccaggagaa gatggccggc aacgacgacc cgcacttcca gacgcgcgcc
     8101 acggtcatca aggagcagcg cgccgagctc gcgaagcacc acgtctccgt gctgtggagc
     8161 gactacttca agccgccgca cttcgagaag tacccggagc tgcaccagct ggtcaacgac
     8221 accctgaagg ccctgtcggc cgccaagggc tcgaaggacc cggcgaccgg ccagaaggcc
     8281 ctggactaca tcgcccagat cgacaagatc ttctgggaga ccaagaaggc ctgacgaggg
     8341 tcagcgcctc gggccggcga tcggtgcacc atcgcaggcc gcagcggagc ccgaaggggc
     8401 ccggccgcca tcccggccgg gccccttcgg cgttgccgtg gtcagggttt ctccgcggtc
     8461 gcccctcggc ggtgtcgctc ggtcccgggc cgcgtgcggg tgcctgcggt gcgggtgtcc
     8521 ggctcgggac ctgccgcgca ctccgggttg tggcacgggc cgggtcccca ggtcggaacc
     8581 cacgcgccca gcgtcttgtg gcgccgggcg accgcttcga ctggctgtcc gcacacggga
     8641 cagacgtacg tgtcgctgtc catgtcccca gggtagaacg ggcggcggct cagcgcttcc
     8701 ggtggtacgt gcgcaccacg gcgccgttgc cgaagctccg caccgagtac gagacgaact
     8761 cggagacctc gaaggcggag gcgaacatcg gcatgccggt accgaggatc accgggtagg
     8821 tcttgatgac cagctcgtcg atctcgtcga ccagctcccc ggcgacgacc gacccgccgc
     8881 acaggtagat gtccaaggcg ctgtcctccg ccttcagctc ccggacccgg ccgaccaggt
     8941 ccgccgagac gatctcgacg cctcgtcgac gaacgggtac atgaacgacg cgtcgccgtc
     9001 cggcccgccg atgaagccgt cgatcgaaca ggcgatgaag tacgtgagct tgcgcaaacc
     9061 ggtctcccct acaggtcgaa cacgttgacc actacggcca cagtactccg cgtgtagttg
     9121 tatggattac gcgttcatcg ggtccggggc tcgcgccaca tgggccacat acagggaccc
     9181 tccggcagat ccacggcccg cccggtgaac tcgaaaccga ggcgttcgta cagcgccttg
     9241 ccccgggcgc tgctcgcctc cagataggcg ggcagcccct cgcggtcgca gcggtcgagc
     9301 acgctctcga tcagcgcggt gcccagcccc tcgccctgcc gcccggggac caccccgatc
     9361 atccacaggt acgcgtgggc ccggccggtg gggtggatgc cctccgtgag ccgggctatc
     9421 gcctccacgc gctcgttgtc cgggtcgacg gcttcgcgga tccgggcggg cacgtcctcg
     9481 acgtccgcgc cggacccgct gtccggctcg gcaccgggat actcgtccgc cgggacgggc
     9541 agccacagcg cgcaggcggc accgtcctcc gtgaggtcga tgcgtccgtc ggcgaagacg
     9601 gcgtcggcga acgcggccat gagccggtgg tgcgtccgtc gccggtactc ctcgccgggg
     9661 aagacccagc tgctcaccgg atcgtcctgg aacgcctcgt ccagcagccg gacgaccaga
     9721 tcccggtcgt ccgcccccgc cgtccggatc gccacaccca tgcctcgccc cttcgactca
     9781 acgccgtctg catgtacggc ggttgagcct atccggtggg ccccacaccc agcgggagag
     9841 acggggaggc gggccccgca caccgtgggg aagtgcggga cccgccggac cggagccgtc
     9901 ggcggtgcgg ccgtacgtcg gtcaggtgcc gtacggccct gcacgggctc cggggtcttg
     9961 cgccggccgc tccggcggtt cacgcccgcc ggggcggccg tcaggtgctg cgccgggtca
    10021 cgaactcggc cagcgcgagc agtccgcccg ccgcctccgg ggcgggcacg gcacgggcca
    10081 gctcctgcat ggctctggcc atccggtcgg ccgcctgggc ctgcgcccag tcccggccgc
    10141 cggcccgctc caccaccagg gcggtgcgct ccaggtcctc cttgtcctcg tcgtacggtg
    10201 ccgcgtacaa ctcggcgagt tcggcggcgg ccggagtgcc ggaggtgagg gcggcgacca
    10261 ccggcagtga cttcttgcgg gcggccaggt ccgcaccggc cggcttgccg gtgtggcgcg
    10321 ggtcgcccca tatgccgatg acgtcgtcga tcagctggaa ggccagcccc gcctcacggc
    10381 cgaaggcgtc cagggcatcg acgtcctccg gggcggcgcc cgcgtacagc gcgccgaggg
    10441 cacaggcaca gcccagcagg gcacccgtct tggcctcggc catggcgagc gtctcgtcga
    10501 gggtgacctc gcccggtggg cgcccctcca gcgccgtgtc cacgtgctgg ccctcgcaca
    10561 gctccatgac gcagtcggag agccgggcgg ccgccgccgc ggacgcgggg tgcgggtccg
    10621 cggcgagcag ccgcagggcg agcgcctgaa gggcgtcccc ggcgaggatc gcgtcggcga
    10681 caccgaacac ggcccaggcg gtcggccgat gacgccgggt gacgtcccgg tccatcacgt
    10741 cgtcgtgcag cagggtgaag ttgtgagcca gttccaccgc cgccgcggcc cggccggccg
    10801 ccgcacgggc cgccggcccg ccgagcgcgg tcgccgccgt gaggacgagc gcggggcgga
    10861 tcgccttgcc cgcgttgccc gtcgcgggcg taccgtccgc gtgctgccag ccgaagtggt
    10921 agagcgcgat ccggcgcatc gcatcgggca gcgatgcgat ggcggagcgc agttccgggt
    10981 cgaccgacgc ccgtgactcc ctgaggagcg tggccgcctc gtgcccttcg gccatcaccg
    11041 gcccctgtcc cccggacgac tccgccggct cctcgtcgcg ctgtgtgccg atgaacccgt
    11101 gcgtctccgg cgttccggtg gaacggcgcg tcgcggtggc gccgcgccgg atctccgtca
    11161 tggactcacc ttccccctgg gcccgtccgt accccggggg tgtacccgcc cgggagggcg
    11221 gggacacggc gtccgggaca gtgacgtcac cgccagcggc cgatctcgac gttctccagg
    11281 acgccgagcg cgtccggcac gaggaccgcg gccgagtagt aggccgtgac caggtacttg
    11341 atgatggcct gttcgttgat gcccatgaag cgcaccgaca gactcggctc gatctcgtcg
    11401 gggatgccgg tggcccgcag gccgatgacg ccctggtcct gctcgccggt acgcatcgcg
    11461 atgatcgagg acgtacgggc ctcggtgacc gggatcttgt tgcacgggta gatcggcacg
    11521 ccgcgccagg tcgggatgcg gttcccggcg acgtcgatcg tctccgggac gagtccgcgc
    11581 ctgttgaact cgcggccgat ggcggcgatg gcccgcgggt gggcgaggag cagcttggtg
    11641 ccgcgccggc ggctcagcag ctcgtcgagg tcgtccggac cgggcacgcc gtcgtgcggc
    11701 tggatgcgct ggtcgtactc gcagttgtgc agcaggccga actcgcggtt gttgatgagt
    11761 tcgtgctcct ggcgctcctt cagcgcctcg accgtcagcc ggatctgctg ctcggtctgg
    11821 ttcatcggct ggttgtacag gtcggccacg cgggagtgga tgcgcagcac ggtctgggcg
    11881 acgctcagtt cgtactcacg gggccgggcc tcgtagtcga cgaaggtgtg cgggatgtcc
    11941 ggctcgccgc tgtggccggc ggcgaggtcg atctccttct cgccgtgctt gttggtgcgc
    12001 tgctgcggga cggcgcgtcg ctgctccagg tgctcgcgca gggagtcggc ccgctccgcg
    12061 acctgctcca cctcctggcg gggcagcacg agcaccgtgc aggcggtgac cgtccgggcg
    12121 gtgtactccc agatggcgtc cccgtccagg agcgcctggt cgccgaagta ggcgccgtcg
    12181 gcgaggacgc cgagcaccgc gtcgtcgccg tagggaccgg tgccgatctt ctcgatcttg
    12241 ccgtgcgcca gcaggtagac ctcgtcggtc cggccgccga acgaggcgat gacctcgccg
    12301 gggccgaact cccgctgctc acagcgctgc gcgagctccg acaggacctc gtcgtcctcg
    12361 tacgagcgca gggccggcag ttcgcccagc tccgcgggga tgacctcgac gcggtcgccg
    12421 gtcttcacga acgtcacgcg gccgtcgccg acggcgaagg tcatccgccg gttcacgcgg
    12481 tacgtgccgc cctgaatgtc cacccagggg agcgtgcgca gcagccagcg cgagctgatc
    12541 tcctgcatct ggggaacgga cttggtggtg gtggccaggt tccgcgcggc cgccgtgccg
    12601 aggctctgct gcggcctggt ctgctcggtg cggacctctt cgcctaccga cataaggaat
    12661 tgccctcccg gtcatgccgg acgactgggc ccggcatcga tgtgcgtgga ccagccttcc
    12721 tcacggagcg tgccggtgct attacacgaa agagcgggaa tggatcacgc gcggccgggg
    12781 cagacatgag agcttgttcg gcatctcggc ggcatgtccg actccgtgcg gcccggtccg
    12841 gcgccgacgg ccgggacgag attgtccgaa acggctcgca cacggaccga acaagtaata
    12901 ggagccgctc cgtttcggta caagccccct acgaggcggt cgcgtcgggc ggtcgccgcg
    12961 cagcgcgaag gagccggccg tggcctcacc catgtccgcg agcagtttcc tcaaggccct
    13021 gaaggcggag ggcctcaccg tcgtcgaggt gggcgactgg cgggaccaca accgcgacca
    13081 caagggcccc tggggccccg tgcacggggt gctgctgcac cacacggtca ccaggggcag
    13141 cgcccggacg gtggagatct gccgcaaggg ccacgaggac ctgcccggcc cgctgtgcca
    13201 cggcgtgatc accaaggacg gcacggtcca tctggtcggc tacggccggg ccaaccacgc
    13261 cggtcccggc gacgacgacg tcctgcgcgc cgtcgtcgcg gagaaggcgc cgcccccgga
    13321 caacgaggcc gacaccgacg gcaaccggca cttctacggc ttcgagtgcg agaacctcgg
    13381 cgacggcgac gacccctggc cggcggcgca gctggacgcg atcgagcggg ccgccgcggc
    13441 cgtgtgccgc caccacggct ggaacgagcg gtccgtcctc ggtcacctgg agtggcagcc
    13501 ggggaaggtg gatccgcgcg gcttcaccat ggcatcgatg cgggagcgga tccgcgaccg
    13561 cctcaagtga tcccgaaccg gccggggcga cgtgtccgac gcgggcggcg gcgcgacaat
    13621 ggcggggtga ccggcaccga ctcccgcggc ctcgctgccc tgcggccccg tctgccctcc
    13681 cccttgcagg aggtggccga cgaccgcttc gaacggcgcg gtgtccggct gctgctcaag
    13741 agggacgatc tgatccaccc cgacctggtg ggcaacaaat ggcggaagct ggcgccgaac
    13801 ctcgccgcgg cggacggccg cacggtcgtc acgttcggcg gcgcctactc caaccacctg
    13861 cgggccgcgg ccgccgcggg ccggctgctc gggctgccca cggtgggggt cgtccgcggt
    13921 caggaactgg caggcctgcc gctcaacccg tcgctggccc ggtgcgccgc cgacggcatg
    13981 cggctgcact tcgtcgaccg ctcgacgtac cgccgcaaga gcgaaccgga gaccctggcc
    14041 gcgctgctgc gcgcggtggg cgccgaggac gccgtcgtcg tccccgaggg gggcagcagc
    14101 ccacaggccg tccgcggctg ccgcgcgctg ggcgaggagc tgggcgaaca cgccgacgtg
    14161 gccgccgtcg cctgcggtac cggcggcacg ctggccgggc tggccgccgg gctccccgcg
    14221 gggcggcggg ccctcggcac agccgtgctc aggggcggct tcctggagcg cgacatacgg
    14281 cggctccagg agcacgcgtt cggcgggccg cgcggcacct ggagcctgga ggagcgtttc
    14341 caccacggcg gctacgcccg cacgacgccc ggcctcgacg ccttcgccgc ggacttcgag
    14401 gaccgccacg gcctggccgt ggagcgcgtc tacgtcgcca agatgctgta cgccctgctc
    14461 gcgctcgccg aggagggcgc ctttccgcgc gggacgaccc tggcggcggt cgtcaccggc
    14521 cggcccttcc cctgagcggt cccccgccgc cgcgcccgtg cgccgctcag gtggtctccc
    14581 ggtacgccgc cgcctcctcc aggtccagcc ggcgcagcag cgtccggagc atctcgtcgt
    14641 cgatgtagcg gccgtcccgc aaccggacga agacctcgcg ctcggcgccg atcatctccc
    14701 gggagagccg ccggtaggtg tcgtcgacgg tctcgccggt gacgggattg acctggccca
    14761 gccgttccca gaccgcgttg cggcggcgct ccaggaccgt gcgcaggcgg tcggcgagcg
    14821 ggaccggcag ggcgttgcgc tcgtcggcga gcagggcgtc caggcgctcg tccgcgaccc
    14881 gcgaggcctg cgcctgggcg ttcgcctccg ccagcgtctc ggcccgcgcg tcgtgcgccg
    14941 ggaacttcag caggcggatc agcggcggca gactgacgcc ctggacgacc agcgtgccga
    15001 tgaccgtcgt gaaggtcagg aacaggatga ggttgcgctc ggggaagggc tcgccgccgt
    15061 gcacggtgag cgggatggag aaggcgatgg ccagggagac cacgccgcgc atcccggccc
    15121 agccgatgac gaacggcccc ttccaggaga gctcgccctc gcgcgcgcgt acgcgtgccg
    15181 acagccgggg caggaaggtc gccgggtaca cccacacgaa cctcgccacg gcgaccacca
    15241 ggaagacggc gagggcgtac ccggcggctt cggcgccctc gtactccccc aagcccttga
    15301 ggacgacggg cagctggagt ccgatgaggg cgaacacggc cgactccagg acgaacgcga
    15361 ccatcttcca gaccgcctcc tcctggagcc gggtggcgaa atcgacctcc cacgcgcggt
    15421 ggcccaggta gagggcgacg acgaccaccg cgagcacccc cgaggcgtgc acctgctcgg
    15481 cgaccgcgta ggcgacgaac gggatcagca gggagagcgt gttctgcagc agcgcctccg
    15541 tcaggtgggt gcgcagccag tgcagcggca ccatcaggac cagcccgaca ccgacgccgc
    15601 ccaccgcggc gatcaggaac tcgccgatcc cgccggccca ggtggcgccc tcgccgacgg
    15661 ccgccgcgag cgccaccttg aaggcggtga tcgcggtggc gtcgttcacc agggactcgc
    15721 cctggaggat cgtggtgacg cgcgagggca gccccacgcg tcgggcgacc gccgtggccg
    15781 cgacggcgtc cggcggcgcc acgaccgcgc cgagcaccag cgccgcggtc agcggcaggc
    15841 ccggcacgat gaagtaggcc gcaccgccga cgacgaaggt ggcgaacagg acgtagccca
    15901 cggacagcag ggccaccggc cgggcctgcg cccgcaggtc caggtaggag ctgtcggtgg
    15961 ccgcagtgta gagcagcggg ggcagcagca ggggcaggac gatgtgcggg tcgagggtgt
    16021 agtcgggcac gccggggacg tagctcaccg ccaggcccgc cgcgaccagc agcagcggta
    16081 ccggcaccgg cacgcgccgt cccgccccgg cgaccgcggc actgcccgcc accagcaaca
    16141 gcagcggcat cacgtccatc gtcctcgccc gccctcgtct tccgcgcggt catccgcaca
    16201 cccgtcgtaa cctggcaatc atgaaacagt gcacgcacgc cgacgcgctg ccgcacccgg
    16261 aacccgagcc gtgcggcgag acctgcccgg agtgcctggc cgagggcacg gacccggtgc
    16321 agctgaggct ctgtctcagc tgcggtcacg tcggctgctg cgactcctcg ccgcggcggc
    16381 acgcgacggc gcatcacgcg aagaccggtc atccggtgat gcggaccttc gagcccgggg
    16441 agagctggcg ctggtgcttc gtcgatcacg tcctcgtgtg acctctgccc gggacggttc
    16501 gaccgtctga cgtctgggta cgtcaacccg gcgcacgctc ttccgatttg ggcccgccga
    16561 ccccctagcc actgtgcgtg ttcgcgtgtt tactatgagt gacagcacgg ggttggggtc
    16621 tcggggacag gaaacttcgg agcgcgataa cgtcaccgct gaaccacgta tcgcgttatc
    16681 ccgaggggcg tccctcggcc ctgtaacgct tgtaccacct tggaggtgag ggtgtcccag
    16741 atcgcaggcg agcccgcgac ccaggacttc gtcgaagtcc ggctgccggc cgcgggtgcc
    16801 tacctgtcgg tgctgcgtac ggcgacggcc ggcctcgcag ctcgtttgga cttcaccctc
    16861 gacgagatcg aggacctgcg catcgcagtc gacgaggcct gcgcgatcct gcttcagcag
    16921 gccgtgcccg gctcggtgct cagttgcgtc ttccgcctcg tcgacgactc gctcgaggtc
    16981 accgtctcgg cgccgaccac ggacggccat gccccgtcgc gggacacctt cgcgtggacg
    17041 gtgctctccg ccctcgcggg caaggtctcc tccgccgtgg acgaggacaa aaccgtttcg
    17101 atcagcctct acaaacagcg cggcgcggga cccgggccga cgtgagggac ggggacgggc
    17161 cggtgcggga cgaagagcgc ggtacacggg agctgccggc cgagggcaca cgttctccga
    17221 acgaggcgcg acgcacggcg gacggcatcg acggcatccc cgagcaggcc cggccgcatc
    17281 cggaggacga gacctcgccc gaggccgtcg ctccggtcga cgggcagcgg accggggaca
    17341 cccccgtccc gcccgtccga ccggaggagc gggctcggga aagggcgacg ggcgggacga
    17401 tgagcgagca cgagcgacac tccgacggcc acgcgccggg tgcacggggc acgcagggca
    17461 cacggcacga cccgcacgac cgcagcggtg cgcgcctcct gttcgccgag ctgcgcacgc
    17521 tgacgaagga cagcccggag tacgcggagc tgcgcaaccg gctggtccgc atgcacctgc
    17581 cgctcgtcga gcatctcgcg cgccgcttcc gcaaccgcgg cgagcccctg gacgacctca
    17641 cccaggtcgc cacgatcggg ctgatcaagt cggtcgaccg cttcgacccg gaccgcgggg
    17701 tggagttctc cacgtacgcg acacccacgg tcgtcggcga gatcaagcgg cacttccggg
    17761 acaagggctg ggcggtgcgt gtcccgcgcc ggctccagga gctgcggctg gccctgacga
    17821 cggccacggc ggagctgtcc cagctgcacg gccgctcccc cacggtccac gagctcgccg
    17881 agaagctggc gatctcggag gaggaggtcc tggagggcct ggagtcggcc aacgcgtact
    17941 ccacgctgtc cctggacgtc ccggacaccg acgacgagtc cccggccgtc gccgacaccc
    18001 tcggcgccga ggacgaggct cttgaggggg tcgagtaccg ggagtcgctc aagccgctgc
    18061 tcgaagacct tccgccgcgg gagaagcgca tcctgctgct gcgcttcttc ggcaacatga
    18121 cgcagtccca gatcgcgcag gaggtcggga tctcgcagat gcacgtgtcg cggctgctgg
    18181 cccgcacgct ggcgcagctg cgggagaagc tgctggtcga ggagtagccg cgcggccgcc
    18241 cggcagcggg cggggcgtcc gccggctact tcccggcgtt gcccggtccc cggattccga
    18301 gggccagggt ggtctcgggg ttgatgagca ggtacagagc ggtgagcgcc gcgacaccga
    18361 gcacgacgcc ggcggggacg gccaggccgt cggcccccgc catgttgtag gcgacgggca
    18421 gcgacacgat ctgcgtgatc acggcgggcc cccggctcca cccccgcagg cggagcagcc
    18481 cgcgggcggc gagcagcggc agcagggcga ggacgatcag ggtgatgccc ccggtgacgg
    18541 ccgcggtccg gtcgtcgggg tgcccggtga ggccctccac gagcatccag gcgccgccga
    18601 cgacgagcgc caggccctcc agcgcggcga tcgcggccgc ggcggtcact cgtacggggc
    18661 ggggctctgc ctcttcggcg gccggggagg cggggtcggg ggtctgctcg ctgctcaccc
    18721 ctgcagggta gccgtcggcg cacccgcgtc cccggccgcc cgggtgtcgg gcgtatcacg
    18781 cggcgcgggc cccggtgggg atcttcacat cggtctgggc cgagtaccgc ccagtaggta
    18841 ccctgcacag catgcgtgca cttctcgtgg tcaatccggc ggcaaccacc acgagtgcgc
    18901 gtacgcgcga cgtgctgatc cacgcgctcg cgagcgagat gaagctggag gcggtcacca
    18961 ccgagtaccg cggccacgca cgcgacctcg gccggcaggc ggcgcagagc gacgacgtcg
    19021 acctggtggt ggccctcggc ggcgacggca cggtgaacga ggtcgtcaac ggtctgctgc
    19081 acgcgggccc cgacccggat cacctgcccg gcctcgcggt cgtccccggt ggttccacca
    19141 acgtcttcgc ccgcgccctc ggcctgccca accacgcggt ggaggccacc ggggccctgc
    19201 tggacgccct gcgcgagggc agcgagcgga ccgtcggcct cggcctggcg tcgggtacgc
    19261 cgggcacgga ggacgaggcg gtcccggccc gctggttcac cttcaacgcc ggcctggggt
    19321 tcgacgccgg tgtggtgggc cgggtcgagc agcatcgcga gcgcggcaag aagtcgacgc
    19381 acgccctcta cgtccgtcag gtggtgcgcc agctcatcgg cgagccgcac cgccgcagcg
    19441 ggacgatcac gctggagcgg ccgggcgagg acccggtcac cgatctggtg ctgtccatag
    19501 tctcgaacac ctgtccctgg acgttcctcg gcaaccgtcc gatctacgcc tccccccagg
    19561 cctcgttcga caccgcgctc gacgtcttcg gcctcaagcg gctgtcgacc gccgccgtcg
    19621 cccggtatgg cacccagttg ctcacttcgt cccccgagcg cggaccgcgc ggccggcacg
    19681 cggtcaccct gcacgacctg accgagttca ccttgcattc gaaggtgcct ctgccccttc
    19741 agatggacgg tgaccacctg gggttgcgca ccagcgtgac gttcacaggc gtacgccgtg
    19801 cactgcgtgt gattgtgtga gcagaagggg cgaaagtcct ttcactcgaa cgtttagacc
    19861 agcatccacc ccatggaagt acggctgtga cctagtcgac accgaagaat caaaaaaaac
    19921 tttccggaag gggttgtatc cgccgccgag gtttgcgagt ctcttcttgg cgatcgggac
    19981 agcccgcaag accggcatcc acagatcacc ggaacccctc ttcaaaccac aggaccacgc
    20041 cagggaacct ggcggtaggc ccttcccttg ttgagggatt cgtgaaagcg ttcacattca
    20101 caagcagccc agcatgtaat accaaggaga ggtagcagcc atggactggc gtcaccgcgc
    20161 cgtttgccgc gaggaagacc ccgagctctt cttccccatc ggcaacaccg gtcccgcgct
    20221 gctgcagatc gaggaagcca aggccgtctg ccgtcgctgc cccgtcatgg agcagtgcct
    20281 gcagtgggcg ctcgagtccg gccaggactc cggcgtctgg ggtggtctca gcgaggacga
    20341 gcgccgcgca atgaagcgcc gtgccgcccg caaccgggct cgtcaggcct ccgcctgaca
    20401 acccacccct actgacagcc tcagcttggc ggcgcgtaca gcgagtacgc atcccccgct
    20461 cccgagccgc agcgcgcagt acccccgatg cgcatcggac gacacagcgc acgagcactg
    20521 gcctcggacc ctcaccggtc cggggctttt tgctgtgcgc acggccctgt cggccgctcg
    20581 tgctacttct cggcgggcac cgggatgtcg aggatcaccc gggtgccgcg ctccgcggcc
    20641 gggaccatgt cgaagctgcc gcccaactcg ccctccacca gggtgcggac gatctgaagg
    20701 ccgagattgc cggagcggtg cgggtcgaag tcctcgggca gcccgacgcc gtcgtcctgg
    20761 acggtgacga gcagccgggc ctccttggtc gtaccgccgc gcacggccga gacctcgacc
    20821 gtgccggtgt cgctgtcccg gaagccgtgc tccagggcgt tctgaagcac ctcggtcagc
    20881 accatggaca gcggggtggc gacctcggcg tcgaggatgc cgaagcggcc ggtgcgccgg
    20941 ccggtgaccc tgcccgggga gatctcggcc accatcgcca gcacccggtc ggcgatctcg
    21001 tcgaactcca cgcgctcgtc caggttctgg gagagcgtct cgtgcacgat cgcgatcgag
    21061 cccacccggc gcacggcctc ctccagtgcc tcgcggcccc ggtcggactc gatgcgccgg
    21121 gcctgtaggc gcagcagagc ggccaccgtc tggaggttgt t
//
