LOCUS       NZ_NBBO01000003        21612 bp    DNA     linear   CON 10-JUL-2024
DEFINITION  Bacillus subtilis strain TS4 scaffold_3, whole genome shotgun
            sequence.
ACCESSION   NZ_NBBO01000003
VERSION     NZ_NBBO01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 137088)
  AUTHORS   Kaul,S., Sharma,T. and Dhar,M.K.
  TITLE     Whole genome sequence of Bacillus subtilis, an endophyte of Crocus
            sativus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 137088)
  AUTHORS   Kaul,S., Sharma,T. and Dhar,M.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2017) School of Biotechnology, University of
            Jammu, B. R. Ambedkar Road, Jammu, J&K 180006, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 96.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010634645.1-RS_2024_07_10
            Annotation Date                   :: 07/10/2024 04:09:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,571
            CDSs (total)                      :: 4,476
            Genes (coding)                    :: 4,266
            CDSs (with protein)               :: 4,266
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 210
            CDSs (without protein)            :: 210
            Pseudo Genes (ambiguous residues) :: 0 of 210
            Pseudo Genes (frameshifted)       :: 144 of 210
            Pseudo Genes (incomplete)         :: 72 of 210
            Pseudo Genes (internal stop)      :: 24 of 210
            Pseudo Genes (multiple problems)  :: 27 of 210
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 100019
            Orig. end                         :: 121631
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NBBO01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="2"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](-)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11612)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            complement(421..540)
                     /gene="phrF"
                     /locus_tag="B6K89_RS01765"
                     /old_locus_tag="B6K89_01785"
     CDS             complement(421..540)
                     /codon_start=1
                     /gene="phrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391627.1"
                     /locus_tag="B6K89_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01785"
                     /product="phosphatase RapF inhibitor PhrF"
                     /protein_id="WP_041334633.1"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALCTVFVATTIANAPTHQIEVAQRGMI"
     gene            complement(524..1669)
                     /gene="rapF"
                     /locus_tag="B6K89_RS01770"
                     /old_locus_tag="B6K89_01790"
     CDS             complement(524..1669)
                     /codon_start=1
                     /gene="rapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="B6K89_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01790"
                     /product="response regulator aspartate phosphatase RapF"
                     /protein_id="WP_041334636.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQFIQGGVSLYEIEV"
     gene            1672..1902
                     /locus_tag="B6K89_RS23125"
                     /old_locus_tag="B6K89_01795"
     CDS             1672..1902
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="B6K89_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01795"
                     /product="hypothetical protein"
                     /protein_id="WP_041334639.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSV
                     YPQQFVQANTLLFHILLYLREQCMSEKEVKE"
     misc_feature    complement(1702..1718)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            1899..3253
                     /gene="ywhK"
                     /locus_tag="B6K89_RS01780"
                     /old_locus_tag="B6K89_01800"
                     /pseudo=""
     CDS             1899..3253
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="B6K89_RS01780"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01800"
                     /product="YncE family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLGSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFMSGSEVYLLTASLAIYILSVRMEQV"
     gene            3293..4669
                     /gene="ywhL"
                     /locus_tag="B6K89_RS01785"
                     /old_locus_tag="B6K89_01805"
     CDS             3293..4669
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="B6K89_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01805"
                     /product="YncE family protein"
                     /protein_id="WP_163189206.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDFPEGFKVDTAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGAITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTIVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPKDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    complement(3309..3326)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(4675..5376)
                     /gene="albG"
                     /locus_tag="B6K89_RS01790"
                     /old_locus_tag="B6K89_01810"
     CDS             complement(4675..5376)
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="B6K89_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01810"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_163189207.1"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMASYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(5373..6653)
                     /gene="albF"
                     /locus_tag="B6K89_RS01795"
                     /old_locus_tag="B6K89_01815"
     CDS             complement(5373..6653)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="B6K89_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01815"
                     /product="pitrilysin family protein"
                     /protein_id="WP_163189208.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 8.3e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     SRILFQLDSPFFQEIQQTYRLEINRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            complement(6658..7818)
                     /gene="albE"
                     /locus_tag="B6K89_RS01800"
                     /old_locus_tag="B6K89_01820"
     CDS             complement(6658..7818)
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="B6K89_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01820"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_163189214.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.4e-06,
                     bitscore: 21.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGYAAGSRFMYSANLFFDQQLKTCGNRLIHPLYNGNLHVDALMKTFADLSFPS
                     SLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            complement(7808..9118)
                     /gene="albD"
                     /locus_tag="B6K89_RS01805"
                     /old_locus_tag="B6K89_01825"
     CDS             complement(7808..9118)
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="B6K89_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01825"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_128738344.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     WMFLLHAAIFACVCLSAALMPAATIPLCAVHILWAVVIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            complement(9111..9830)
                     /gene="albC"
                     /locus_tag="B6K89_RS01810"
                     /old_locus_tag="B6K89_01830"
     CDS             complement(9111..9830)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="B6K89_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01830"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            complement(9827..9988)
                     /gene="albB"
                     /locus_tag="B6K89_RS01815"
                     /old_locus_tag="B6K89_01835"
     CDS             complement(9827..9988)
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="B6K89_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01835"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            complement(10001..11347)
                     /gene="albA"
                     /locus_tag="B6K89_RS01820"
                     /old_locus_tag="B6K89_01840"
     CDS             complement(10001..11347)
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="B6K89_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01840"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_024573031.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.7e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 4e-46, bitscore:
                     150.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.1e-07, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.6e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.7e-11, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.4e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        complement(11057..11332)
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B6K89_RS01820_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="B6K89_RS01820"
                     /locus_tag="B6K89_RS01820"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            complement(11372..11524)
                     /gene="sboX"
                     /locus_tag="B6K89_RS01825"
                     /old_locus_tag="B6K89_01845"
     CDS             complement(11372..11524)
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="B6K89_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01845"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            complement(11481..11612)
                     /gene="sboA"
                     /locus_tag="B6K89_RS01830"
                     /old_locus_tag="B6K89_01850"
     CDS             complement(11481..11612)
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="B6K89_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01850"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 3e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="B6K89_RS01830_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="B6K89_RS01830_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     misc_feature    complement(11703..11718)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     gene            11925..12353
                     /gene="ywiB"
                     /locus_tag="B6K89_RS01835"
                     /old_locus_tag="B6K89_01855"
     CDS             11925..12353
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="B6K89_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01855"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     gene            12350..14020
                     /gene="argS"
                     /locus_tag="B6K89_RS01840"
                     /old_locus_tag="B6K89_01860"
     CDS             12350..14020
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="B6K89_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01860"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     misc_feature    complement(14075..14090)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            14155..15342
                     /gene="narK"
                     /locus_tag="B6K89_RS01845"
                     /old_locus_tag="B6K89_01865"
     CDS             14155..15342
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="B6K89_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01865"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_014478287.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     gene            15440..16156
                     /gene="fnr"
                     /locus_tag="B6K89_RS01850"
                     /old_locus_tag="B6K89_01870"
     CDS             15440..16156
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="B6K89_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01870"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_003227573.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(16189..16908)
                     /gene="ywiC"
                     /locus_tag="B6K89_RS01855"
                     /old_locus_tag="B6K89_01875"
     CDS             complement(16189..16908)
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="B6K89_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01875"
                     /product="YwiC-like family protein"
                     /protein_id="WP_144530515.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQQWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     misc_feature    16979..16994
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            17052..17528
                     /gene="arfM"
                     /locus_tag="B6K89_RS01860"
                     /old_locus_tag="B6K89_01880"
     CDS             17052..17528
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="B6K89_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01880"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_014478284.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDSRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(17619..17633)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     misc_feature    17620..17633
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    complement(17642..17657)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            17723..21409
                     /gene="narG"
                     /locus_tag="B6K89_RS01865"
                     /old_locus_tag="B6K89_01885"
     CDS             17723..21409
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042126 - nitrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="B6K89_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_01885"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_163189209.1"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQTHQNPLDAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRQTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNIVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPAFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    21487..21501
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
ORIGIN
        1 aggatcatga gccgatccaa atgggcaaac tcctccaatt tcatggcctg tctgctccag
       61 tacctcatta ggagagagca ttcttgcttt aaagccaaat gttgcctgga ctttttgttg
      121 tcgatcttgg catcgccggc tgccacaatc agaatcgcct gatctccttc ccctctgaag
      181 gacagggtct tggcgattct agccgggctc acgccggtcg tctcagctgc ctgttcaact
      241 gtcgcgctcg acgtttcgaa ctccgtcaca tcattttcta gattccactg tttaaagtgg
      301 gttctcacac tttccagaga catgctgcat ttccactatt tttaagatta ttgaaaaaat
      361 cttagcatgg attgggagac tgggtaaaga ggggacaaaa aaaccgccga tggacggcgg
      421 ttaaatcatt cctcgttgtg caacttcaat ttggtgtgta ggtgcatttg caatagttgt
      481 tgccacgaac acagtgcata gagccagaca agagagtaat agtttagact tcaatttcat
      541 acaaactcac tcctccttga ataaattgcc ttacttgttc caccttcaaa aaataagcag
      601 aagctttttg aaaattttta cgttcatgat aatattttgc cacatcaata gcgaaatctt
      661 caagatcagc atacaacatt ttactttcga gaaaatcaaa aaatccttga attgcttctt
      721 catccggccc tgataagtat aaagatttca aaaattcaaa ctctgataaa tatattacat
      781 ctccggcctt ttgtgaataa gccattccct tactatgata ttcatgagct ttatccattt
      841 ttcctaattt ataatggatc tgtgtaatta aaaaatacgc ttgaggtaag gaaggaagaa
      901 tatttgattc ttcaaaaaca gctattgctc ttttgaaata aggtatggca tcctcatatt
      961 ggctttggct gtttttacaa agcccgatat tgtacaaagt tcttcccatt aattggggct
     1021 gcttttcagc ttctgccata gaataagctt tttgaaaatg tgagacggca tcctcatact
     1081 gttttaaatc taaaaaattg gtggcaaata aagaatgaca ctgcagcaat cttatattat
     1141 aagcttcatt ttctttgtat atttcatatg cttgccgtgc atagtccatt gaaaaatacg
     1201 tttgtttcat atagtaataa gattcagaca tcttaaagaa aaactcagct ttctctatcc
     1261 gatccttaac gaatatcagc ttgctttcgg cctttttgaa aaatttaata gccgacagat
     1321 attcccgctg atccagctca tacatgcctc tgaagaaatt aaaatagtac tcaagcagac
     1381 cagttaaacg agcctgtttt ttatcaatct caagcagcag atcagacagt ctcggctgtt
     1441 cctcaatcct cattttttct aacggttcaa ggtactcaag catcaggttg tgccgaaact
     1501 ccatcagtga atagtacaaa tgaaggtctt gatcttcttc catttgatcc agctcttgct
     1561 tgatttctcg tcgcaaatat tctgcatcgg gtatgctaaa tcggcgtatg tacatatacc
     1621 attcgttaat cttttctccg atggaagaag aagatatgac acctgtcacg tttgcaaatc
     1681 cctcccttca taattctata tatgtcatat tttatcatca acattcttgt gagaagcgca
     1741 aaaaaaccgc aattttttct ttcgttacac cgcatgtttg gagatatatt ttcaaaaaga
     1801 agcgtttacc ctcagcaatt tgtacaagca aacacgttac tcttccatat tctgttatat
     1861 ctgcgtgagc agtgtatgtc tgaaaaggaa gtgaaggaat gagaaaaaat aagctttcct
     1921 ttaaagaaaa agcaggagca gaacaagaag agtgcttatg tttttgtgag ggagaagcaa
     1981 gccgagaagc catgtttcaa gcgccgattg aattacctga aggatttgtc gttgatccgg
     2041 ctgaagctgt tgcaaacgtg acgtggaatg cagacagcct ttcttgtgtc agtgaccgtt
     2101 gcttaattca aacggggcca gagcctgatg aggtcggtgt tcaatttgca gtgcgcctgc
     2161 agggaaccgt tacgctactc ggcagtgtct cacctgtgcg aaatcaatat ggacaagggg
     2221 acggagctgt ttccgtcatt cacaatgcag aaatcgatca agtcgtctat tattccgatg
     2281 aaccggatga ttgcccggat atcagtgaca tcacgattga gaaccttgtt gttgttccgc
     2341 cgttttacgg cagtccttta tcggtgacgg ggacgattgt gcttgtaccg gagccggaac
     2401 ccgtctacgc gtttacagcg aatccaaatg atcaatcagt ttctgtgatt gatacaaaca
     2461 cccatactgt tgtgacaacg attgctcttc cgtacaatcc ggcaggtatt gaaattacgc
     2521 cagataaaag cgctgtgttt gtcttacatc ccaacaataa tgtgatttct gtcatcgatt
     2581 atgacacatt aacagtgaca gcaactatat tgctggatca gccgcctcga ttgataagat
     2641 ttatccctaa tcatgagttt gcttatgttt tcaccggtac tgccatttat gtgattggaa
     2701 ttgatacgtt gactgttgag aggtctattc ctgtagaagg ttttgatatt gcaattgacc
     2761 ccaatgggtt gttcgcctat gttcttaatt ttgggttagt gcaaaaagtg gacttatcta
     2821 ccggtgaagt cttaggaacg attgaacgag agcttatcgt atcatccata gaaacagatt
     2881 ctacggagcg gtatgcgtat gtattagaac aagaattctt attcaattat ttgacggtta
     2941 ttgatttaaa tacgtttacg atcagggata cccaagagct ggagcctgac gggctatatg
     3001 taatgtttat gagtggatca gaggtgtatt tactgacagc ttcactggca atttatattc
     3061 tgtcagtccg aatggagcag gtgtaattgg aaatcttccg caatcagcaa gagactttgc
     3121 gtttaccccg aatggcaaat ttctgtatgc aacccatttt tcagagcaga acatcactgt
     3181 ttacaacacg gatgattatt ctgtggaaac tgtcatatct cttggggttt caccgggagc
     3241 tattgcgatc taatcaactg aatgctgtgc atttttaaaa ggacgtgaaa tcatgaaaaa
     3301 gaatgatctt tctgctttac aggaaaattg tttctgtttt tgtgatgagg aaattagccg
     3361 ggaagcgccg tttcaagtgc cgatagattt ccctgagggc ttcaaggttg atacggccga
     3421 agcgtcagcg gctgttacat ggagtacaga caatttgtcc tgtatcagtg agccttgctt
     3481 aatccagact gggccggaac cagaagatat cggtgttcga tatgccgtga gagtacaagg
     3541 ggccattacg cttcttgtca gtgtgtcgcc tgtgcgaaat caatatggac aaggagacgg
     3601 ggctgtttct gtgattcata ctgaagagat tgatcaagtt gtttattatg cagcacagtc
     3661 tggccgctgt cctgatttca gtcaaatgac agtggaagat cttctcatcg tgccgccttt
     3721 ctacggcagt ccgctcacgg tggccgggac acttgtttta ccgccatcgc cagaccctca
     3781 atcgtatgtg tttactgcca atactggaga cagcacggtt tcggtcattg atgcagattt
     3841 aaacactatt gtaaaaacaa tcccgttttc tgacgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg aaataccaac cttgtctcag tgattgataa
     3961 taaaacatta accatcataa ataccattac tgttggagga gggccgagaa agatcgaatt
     4021 tgatccaaaa gatgagttcg catacgtgat ggccgccgga tctatatatg tgattaacac
     4081 ggcctctcaa tcggtcattg atgtcattcc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tataaatact gggcagttgg tagaaagtat catagataca tttgaatttc ccagtttaat
     4261 tgcaactcct tacgctggaa attttgcgta cgtgttgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt ctccattaag caggggaggg gacttcagcc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagcactaga gcttattttc tagagccata
     4441 tagtgaaccg tttcttatta ataacttata tgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg tctctccccg gcgcttttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gaccgtgtac cgcacaagtg attatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggtagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagcg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaatatgttc gcatgcaaaa caataaatac aggatcagta gcatcgcaag
     4921 tcccattgaa agggcagggg gcgtgtgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaag tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga cataatgaag atagagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagcc cgagccgcac agcgtcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggccacgg cctgaaccca gccgaaggaa taagacgcca tacctataag
     5341 cagcagtaaa agggtaaaga cagtgttttt tttcattgtc tgatcgcctc tttctgagaa
     5401 acgtgaatga tcgctttgtt agaagatgcc attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagaatcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catatatata agtctcggct gacaagcgat tgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa cggtgaatct aattgaaata gaatacgaga cgcgatatcc
     5821 caataaagct ttatcgtcaa cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccatgtat cttccatccg ctcctcatca cccagcacca ttttttgtga gagtgctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgcttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag cgtcatccga
     6061 tgggcttgat aggcagcctt ataggctttt tgtaaatcac tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatggtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggaa tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgcg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tcccggcttc caaaatcgat ttttacattg
     6541 cacagccgca ggtgggcgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagctgt tgaaaaaagg ctttcttttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcgcg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gacccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctttctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaaaacatgc cggtttacgg gtattcttcc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg ataaagtccg ttgcgtcgag
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccaaagacct cctcagccaa gcgagccgcc gagtaggaga agggatcagt
     7441 gaatttcttt tcgattttca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcatc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacggtt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcataa ccaaaagcgt caatgatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaattgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgaaata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggctaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aaccgctcca tagctgctgc tccgtctgcc agctgaagga gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttccgcttg atcggaagcg
     8221 tgatgagcag catccggtca tttttttcaa tcgagtacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa tcacttgctg attaaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaacg ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccattctc ttttgtaaaa cgaaaattca gatcgccgca
     8461 taaatgaatg catcttgccc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 ccaccgccca caggatatgg accgcgcaaa gcggaatcgt ggcggccggc atcaaagcgg
     8581 cgctgagaca tacacaggcg aatatcgccg catgcagcag aaacatccag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacaat gtctgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aaagttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgggcgag ccaaaagctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cggatcagcc
     9001 cgatttcaaa cacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat ggggattatg ttattcatgg
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtgaag aatagccgca taatcacaaa atctttgcac gacatcgagc
     9241 aggtgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcat tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaatagggga
     9361 gcgcgcagca ataagcctgt catcaataca accttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta ttttgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acacatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagcgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcaacc cgtaaacggc gcctttttct aaatgtaaat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcatcccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 aatcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt ccggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcgct gaaccgcggc gcttgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg tacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctttca tagggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggacaa
    10441 tatccctgcc tcttccgaaa tcatcaaccc aattgtaaga gaacgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatag
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacgat gattttttgc ttgtaagtct tcaaaagctc caggctctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcgtt tggatggaca aaaatttctc cgcctgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagcc gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggtgagct ttccaaataa cagtgggcgc atttcaaatt acagcggtgc gtcagctcaa
    10981 atgtggcgtg cagcggcatt ggaaattcat tgcttccgct cgtggtgatt gtatggcggc
    11041 tggcccggtt tccaagctga ataacctgct tgttctggag catgttgagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcaaagctc gtaagccgtt ttgttgagat
    11221 ccaaatactc aaagtcagaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 caccctcagg aagctggtga acccttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt tttgtttttc
    11641 tagcagatct atgttgtact tttatcttaa aactatcaaa ttactaattc aatacatata
    11701 ttttgaaaaa aatgttaaaa agaaatgata gatttcggaa aaatgtaaca tttcctaaag
    11761 gtaattagtg atatgatttt ctcttctata taaggaaatg ctttttatga ggtttatctt
    11821 caaatctgat gagcaatgat ggtaagatag aagcagttga agtttacaaa ccgaatgatt
    11881 atactattca agtcaaagtg gaatgatgaa aaggacgtgt cagaatgaag caagagacac
    11941 cgataacact ccatgtgaag tctgtgatcg aggatgacgg aaaccaagaa gtcatcgaat
    12001 tccgcaccac cggattttac tatgtaaaac aaaataaagt gtatctatct tattatgaag
    12061 aacacgactt aggcaaagtc aaaacgattg tgaaagtaag cgaaggcgaa gtcctggtca
    12121 tgaggtcagg cgctgtcaaa atgaatcagc gtttcgtaac gggagcttcc acaattgcta
    12181 aatataaaat gtcatttggt gagcttgagc tgaaaacaag cacaaaatcg attcaatctg
    12241 atctcgatga agaaaaaggc cgtatcagca tcgcatatga catgcatgtc ggagacgagc
    12301 aggagcattt acataatatg acgatcacgt atgagggagg aactcacgca tgaacattgc
    12361 ggaacaaatg aaggacgtgc tgaaagaaga aatcaaagcg gccgttctga aagcgggact
    12421 ggctgaagaa agccagattc ccaatgttgt tttagaaaca ccgaaagata aaacacacgg
    12481 cgactactca acgaatatgg cgatgcagtt ggcaagagtg gcaaaaaaag cgccgcgtca
    12541 aatcgctgaa gagattgtcg ctcattttga taaaggaaag gcttcgattg aaaaactgga
    12601 tatcgccggc ccgggtttta tcaatttcta tatgaacaat caatatttaa caaagctgat
    12661 tccgtctgta ctggaagcag gggaagcata cggggaaacg aacatcggaa acggtgaacg
    12721 agttcaggta gaattcgtat cagcgaatcc gacgggagac cttcacctcg ggcatgcgcg
    12781 cggggcggct gtcggcgatt ccttgtgcaa cgtgctttca aaagcgggtt acgatgtaag
    12841 ccgcgaatac tacattaacg atgcgggaaa ccaaatcaac aatctggcgc tttctgttga
    12901 agtccgttac tttgaagcac tcggattgga aaaaccgatg ccggaggatg gctaccgcgg
    12961 tgaggatatc attgcgatcg gaaagcgtct cgctgaggaa tacggtgatc gtttcgttaa
    13021 cgaagaggaa agtgaacgcc tcgcgttttt ccgtgaatac ggcctgaaat acgagctgga
    13081 aaagcttcgc aaggacttgg aaaacttccg tgtgccgttt gatgtgtggt attcagaaac
    13141 ttcactgtac caaaatggaa aaatcgacaa ggcgcttgaa gcgctccgcg aaaaaggcca
    13201 tgtctatgaa gaagacggcg cgacttggtt ccgttccacg acgttcggcg atgataaaga
    13261 ccgcgtattg atcaagaagg acggcacgta cacgtacctt cttcctgata tcgcgtatca
    13321 taaggacaag cttgaccgcg gctttgataa gctgatcaac gtttggggcg ccgatcacca
    13381 cggctacatc ccgcgtatga aagcggcaat cgaagcgctg gggtatgaaa aaggaacgct
    13441 tgaagtagaa atcattcagc tcgttcacct ttacaaaaac ggcgagaaaa tgaaaatgag
    13501 caaacggacc ggtaaagccg taacgatgcg tgacctgatt gaagaagtcg gtttggatgc
    13561 cgttcgttac ttctttgcga tgcgcagtgc ggacacccat atggattttg acttagatct
    13621 tgctgtatca acatctaacg aaaaccctgt gtattatgca caatacgcgc atgcccgtat
    13681 ttgcagcatg cttcgccaag gagaggagca gggacttaaa ccggcggcag atcttgattt
    13741 cagccatatt caatcagaaa aagaatacga tctgttgaaa acgatcggcg gcttcccaga
    13801 ggcagtggcg gaagcagcgg aaaaacgaat tccgcaccgt gtcacaaact atatttatga
    13861 tctggcttct gctctgcaca gcttctacaa cgcagagaaa gtcatcgacc ctgaaaatga
    13921 agagaaaagc cgcgcgcgcc tggctttaat gaaggcaacg caaattacgc tgaacaatgc
    13981 gcttcagctg atcggcgtat cggctccgga aaaaatgtaa tcacgatcaa aaggacaaag
    14041 tcttcgggct ttgtcctttt ttatgagaaa aacgtgtgat gtaattcaca atcctgtttg
    14101 ccgagttttt gtatgataag actgattatt gaatcattga aaggggcaag ccaaatgatc
    14161 aaccgtcaac acattcaatt atcgttacag tcattaagct tggtggcagg gtttatggtt
    14221 tgggtgctga tttcatcact catttcccaa atcacattag atattcattt aagcaagggt
    14281 gagatttctt tggtgacggc gattcctgtg atcctcgggt cgcttctccg cattccttta
    14341 gggtatttaa cgaacaggtt tggcgcgcgg ctcatgttta tggtcagctt catcctgctt
    14401 ttatttcctg tattttggat cagtatcgcg gattctctgt ttgatttaat cgcaggcggc
    14461 tttttcttag ggatcggggg agcggtgttt tccattgggg tgacctccct cccgaaatat
    14521 tatccgaaag aaaagcacgg tgtcgtcaat gggatttacg gtgcaggaaa tatcgggaca
    14581 gccgttacga catttgcagc gccggttatc gctcaagccg tcggatggaa atcaaccgtg
    14641 cagatgtatc tggttttgct ggctgtcttt gccttactgc acgttttgtt cggtgacagg
    14701 catgagaaga aggtcaaagt ttctgttaag actcaaatca aagccgttta ccggaatcat
    14761 gtgctatggt ttctgagcct gttttatttt attacgttcg gtgcctttgt cgccttcact
    14821 atctatctgc cgaactttct ggtggagcat tttgggctga atcctgcaga tgccggcttg
    14881 cggacggctg gctttattgc ggtttctacg ctgctcaggc ctgcaggcgg attcctggct
    14941 gataaaatga gcccgctccg catcttgatg tttgtttttg ccgggcttac attatcaggc
    15001 attatcctat cgttctcgcc gacaatcggc ctttatacgt ttggatcatt aaccgtggcc
    15061 gtctgctcag gcataggaaa cgggactgtt tttaaactgg tgcctttcta tttttcgaag
    15121 caagcgggga ttgccaatgg gattgtgtct gccatgggcg gattaggcgg cttttttcct
    15181 ccgctcatat tggcgagtgt atttcaggca acaggccagt acgcgatcgg gtttatggcg
    15241 ctttcagagg tggcgttagc cagttttgtc cttgtcatat ggatgtattg gcaggaaaga
    15301 atgaaaacac acacggagag aaacagccag agcatcaact aacactgggc attcacaaga
    15361 ttgttagttt tttctcgatg ggtacaaatc aattcacgtt acaataaaca cacaacgtga
    15421 ctttcttcga ggtgagctca tgaattttct ctctgttcga ccatctgata gtgatcttat
    15481 atccagcgat ctgcatgaat tgctggaatc gatcagcacg aaaagaaaaa tggaaaaaca
    15541 cacgtatttg tttcgggaag gaatggatgc agaagagctt tatctgattc aatcaggact
    15601 cattgaaatc ggcaagctga catctgacgg aaaagacctg acgcttagaa tctgccaaaa
    15661 gcatgatatc gtcggagaat taacactttt cactgaagaa ccaaggtata tgctcagtgc
    15721 aaaagtgcta gaggatggcg aggtgctcgt cattaataaa aataagctgg aaaaagaatt
    15781 aatccaaaat ggcgctttga catttgagtt catgaaatgg atgagcacgc acctccggaa
    15841 gattcagtcc aaaatcaggg atctgcttct tcatggcaaa aagggggcgc tctattctac
    15901 ccttatccgt ttatcaaaca gctacggagt ggagcgaagc gacggcattc tgattaacat
    15961 tgtcctgaca aatcaggatt tggcaaagtt ttgcgcggct gcacgggaaa gcgtcaatcg
    16021 tatgttggga gatctccgca aaaaaggggt tatttcgata gacgaatccg gaaaaattat
    16081 tttgcacaag cgggactatt tacgatgtga gattgagtgt gaaaattgcc cgctggagat
    16141 ttgcaatatt gactgaaaaa aacaaggaca gcggtgtcct tgtttttttt accttgtgat
    16201 aaacaggcac atgacggcaa gaaagaagca ggcattcacg atttccagaa tgccaatcgt
    16261 ttttacgggc caatcccttc catgaaaaaa ccatgcccgc aagctgctcg ggataaaagc
    16321 gagaaacgcc catcctgctc cgaaaagagc ggataaaaag gggagcagca ggtgatatcc
    16381 ccatgaccag tatgcaaatg tcctgttttt tctttcacga atcaccgatt ttacataaaa
    16441 ggaactcccg ataaaaaata aagcagactg caagaaaata aaccaagccc agccgtcgag
    16501 ggttcccatc cccagccagc agctcgcaaa cccgcccgaa caaaagaaca agacacctgc
    16561 aacatcattc aatagggctc gttcgttttt tcggcgggca aaatacatat gtatgagaaa
    16621 cagcggcagt aaagaaacgc ccacccagat gagaggcggc ttatgaaaga ccgagatcat
    16681 caaaaagcag caggcgggaa aaccgtaata acacatccac tgttgatatg gtttgctttg
    16741 tttctttttt aaggcaagcg taacgggata aaccgctaag tataggaaaa gccagcctag
    16801 gaagagcgga atatgccaaa taacggggcc tcccttgacc atgccgagta aaaatgggat
    16861 cagcagcatc gcccacgcgc cgtgctgctt cggaatcagc gccttcatcg aaatcctcct
    16921 tttttctttc attataaatg cagtcaccct cctgataagt gacattcatc atacaggctg
    16981 tgaaatacat cactgctgta caggctcagt cgagctacac taaagctatc cttagcacag
    17041 gaggttttcc tatgaatcag tgtgactatt tattatttct gaaacaactt cctatgttta
    17101 atgaagtgcc tctatccatt gtcgaaactt tgctgaaaaa cggcacgttt atccgcggct
    17161 catgtgatca gtctccatct tttcttcatt ctcaatctgt ctatattgta ttaaaaggca
    17221 gtgtccgttt catggacagc aggctccctg aagggtcgaa aaccgttgcg ctgtgggaaa
    17281 aaggcgatgt gtttccgatt gatgaaaaag gcgggcttta tttatcgccc tttatctcag
    17341 tcaatgccac ttcagacatt ctgattctca acatcccata ttacatattt aagaaaatga
    17401 tgtcttatca tccgcagctg caaatgaact ttttggctat gcttcagcaa aatgtttttt
    17461 gttcctatca attatttttg cggtatctgc atacatcaca ggatgaaaac gccgagcccg
    17521 gttcttaaat agagccggtt tttttgatct ttgaatgaaa ggcagctaat aacccaagcg
    17581 tcctgcctga acgcagcctt ccttctcctt tgtgtgaaca ttttgtgaaa aaagcggagt
    17641 gtgtgacata gttcacaagg aaacacgctg tctctgttta tagtgaactt agcatcacct
    17701 gactcggaag gagtgaactc tcatgaagaa aaagaaaagg agtccgttgt ttaggagatt
    17761 gaattatttc tctcctatcg aacaccattc aaataaacat agccaaacca cccgcgaaga
    17821 tcgcgattgg gagaatgtat acagaaacag atggcagtac gacaaagtcg ttcgctccac
    17881 ccacggcgtc aactgtacag ggtcttgcag ctggaatatt tatgtgaaaa acggaattgt
    17941 cacgtgggaa gggcaaaatt tgaattatcc atcaacaggc ccggatatgc ctgattttga
    18001 accgagaggc tgcccgcggg gggccagttt ttcatggtat atctacagcc cgctccgtgt
    18061 gaaatatcca tacgtgcgcg gtgtgctgat caatttgtgg cgggaggcat tgcagacgca
    18121 tcaaaatcca ttggacgcct ggaaatcgat cgtcgaaaac cctgaaaaag cgaagtctta
    18181 taaacaggcg agagggaaag gcggttttgt gcgcgctgaa tggccggagg tgctgaagct
    18241 gatttcagcc tctctgctgt atacagtgat gaaatacggg cctgacagaa acgtcggttt
    18301 ttctccgatt ccggccatgt ccatgatcag ccatgcatct ggctcccggt ttatgtcgtt
    18361 aatcggaggc cctatgctca gtttttatga ctggtatgcg gatcttcctc cggcatcccc
    18421 gcaaatttgg ggtgaccaga cggacgttcc ggaaagcagt gattggtaca attccggcta
    18481 tatcatcaca tggggctcca acgttccgtt aacgagaacg cctgacgcgc attttttggc
    18541 ggaggcccgc tataaaggcg ctaaggtcat ttcgatcagt ccggattttg cggaatcctc
    18601 aaagttcgcg gatgactggc tgagtattcg ccaagggact gacggggcgc ttgcgatggc
    18661 gatgggtcat gtcattctgc aggaatttta cgtgaaccaa gaaactgaac gttttattga
    18721 gtacgcgaag caatacactg attttccatt tctcgtcacc ctgtcaaaag aaaatggcgt
    18781 atacacagcg ggacggtttc tgcatgcgaa ggacatcggg cggcagacaa agcatgatca
    18841 gtggaagcct gcggtttggg atgaacagac aagttcattt gccatacccc aagggacaat
    18901 gggctcgcgc tgggacgggc agcagaaatg gaacctgcac atgattgatg aagaaactgg
    18961 ggaaccgatt gaaccccgtc tctctgtgct gggaatagag gacgaaatcg gcacggtgcg
    19021 catcccgtat ttttcaaatg acggaaacaa agtgctcgag cgggatcttc ctattaaaaa
    19081 aatgaacctg aacggtgaag aaacgtacat cacgaccgtg tttgacttga tactggctaa
    19141 ctacggcgtg aaccggggca tcggcgaacg atcggctgtc tcctatgatg atcctgagcc
    19201 gtttacgcct gcctggcagg aacaaatgac aggaatcaaa aaagaagctg tcgttaagat
    19261 tgccagagag tttgcccaaa atgcgatcga tacagacggc cggtccatga ttatcgtagg
    19321 ggccggcatt aaccactggt tcaactccga cacgatctac cgagcggtgt taaatattgt
    19381 tttacttgta ggcgcccaag gcgtaaacgg cggaggctgg gcccattacg tggggcagga
    19441 aaagctccga cctgctgaag ggtggcagac gattgcaact gcaaaggact gggagggcgt
    19501 gcctaagctg caaaacggca cctcattttt ctactttgcg acagatcagt ggcgttatga
    19561 ggaccagccg atcagtgatt tggcatcacc gattgctgcg tcatcccgct acaagcacca
    19621 cgctgattac aatgtactgg cggcgcggct ggggtggctt ccgtcttacc cggctttcaa
    19681 tcaaaatggt atcgatctgt ataaagaagc tgaaaaagca ggggcagcaa cacctgaaga
    19741 cgttggtgcg tacgtggcct cacagctcca agagaaaaaa ctgaaattcg cgattgaaga
    19801 tcccgataat gaagtgaatt tcccaagaaa tctcttcgta tggcgggcaa atctgatctc
    19861 aagctcagga aaagggcatg aatattttct caagcatttg ttagggacga cgaacggctt
    19921 gatgaatgac gacagcgaca gcatccgccc tgaagaaatc aaatggcggg agcaggcgcc
    19981 ggaaggaaag ctcgacttgt taatcaatct tgacttccga atggccggta cggcgctgta
    20041 ttccgatatc gtgctgccgg cggcgacatg gtatgaaaaa cacgatctca gcagcacaga
    20101 tatgcatccg ttcattcatc catttgctcc tgcgatctcg gctccgtggg aatcgaagtc
    20161 agactgggat attttcaagg cgctgtcaaa agccgtttcc gatctggcag aagaagtcga
    20221 tatggagccc gtgaaagaag tggttgcgac gccgctcctc cacgacacca tgcaggaatt
    20281 ggcccagcca ttcggcaaaa tcaatgactg gagcaaaggc gaatgtgaag ccattccggg
    20341 aaaaacgatg ccgaacatcc aagtcgttga acgggattac aaacacattt ttcataaaat
    20401 gactgcactt ggtccgaacg ttgctttaaa gccgagcgga acaaaaggga tgagctggtc
    20461 aatagccgat gaatatgaat cactcaaaca gagattggga gaaatcacct cggacagtgt
    20521 cgcaaagggg tgtccaaata taagtgaagc aaagcaggct gcagaagcga ttttaaccct
    20581 atcatccact tcgaatggaa aggtcgccgt caaagcatgg gaatcacttg aaaacatcac
    20641 gaacctgaag ctgaaagacc tggcggaaga acgcgaggaa gaatgcttta cgttcgaaca
    20701 aattacagcc cagccgaaaa cggtgatcac gtctccagcg ttttccggct ctgaaaaagg
    20761 agggcgcagg tattcgccgt ttacaacaaa tgttgaaaaa ttaattccgt ggcggacgct
    20821 gacaggcaga caatcctatt atgtcgatca tgaactgatg atggaattcg gtgaaacgat
    20881 ggcgacattc aaaccgatcc tccagcatcg cccgtttctg agcaagcggc ctgatcaaga
    20941 gggaaaagaa atcgtcctca attatttgac gccgcataat aaatggtctg tccacagcat
    21001 gtattttgat tctctgccga tgctgacgct gttccgcggc gggccaaccg tgtggatgaa
    21061 taaagatgat gcagaggaca cggatatcaa agacaacgat tggattgaat gctttaaccg
    21121 aaacggtgtt gtcgtcgcga gagcggtttt gtctcatcgg attcctaaag gaatggcgtt
    21181 tatgcaccat gcccaggacc gccacatcaa cgtgcccggc acaaagctga cgaataaccg
    21241 cggaggcacc cataacagcc cgacaaggat tcacgtcaag ccgacacaga tgatcggtgg
    21301 ctacgcccag ctcagctacg gctttaatta ttacggtcca acggggaatc agcgcgacct
    21361 gaacgtcgtc atccgcaagc tgaaggaggt cgattggctt gaagattaaa gcgcaaatcg
    21421 gtatggtcat gaacttggat aaatgcatcg gctgccacac gtgcagcgtc acctgcaaaa
    21481 acacgtggac aaaccgttcc ggtgcggaat atatgtactt caataatgta gaaacaaagc
    21541 cgggcatcgg ctacccgaag caatgggagg accaggacaa atataaaggc ggctggacat
    21601 tgaaaaaagg aa
//
