LOCUS       NZ_NBBO01000002        20270 bp    DNA     linear   CON 10-JUL-2024
DEFINITION  Bacillus subtilis strain TS4 scaffold_2, whole genome shotgun
            sequence.
ACCESSION   NZ_NBBO01000002
VERSION     NZ_NBBO01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 230055)
  AUTHORS   Kaul,S., Sharma,T. and Dhar,M.K.
  TITLE     Whole genome sequence of Bacillus subtilis, an endophyte of Crocus
            sativus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 230055)
  AUTHORS   Kaul,S., Sharma,T. and Dhar,M.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2017) School of Biotechnology, University of
            Jammu, B. R. Ambedkar Road, Jammu, J&K 180006, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 96.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010634645.1-RS_2024_07_10
            Annotation Date                   :: 07/10/2024 04:09:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,571
            CDSs (total)                      :: 4,476
            Genes (coding)                    :: 4,266
            CDSs (with protein)               :: 4,266
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 210
            CDSs (without protein)            :: 210
            Pseudo Genes (ambiguous residues) :: 0 of 210
            Pseudo Genes (frameshifted)       :: 144 of 210
            Pseudo Genes (incomplete)         :: 72 of 210
            Pseudo Genes (internal stop)      :: 24 of 210
            Pseudo Genes (multiple problems)  :: 27 of 210
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:42:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 95198
            Orig. end                         :: 115468
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NBBO01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20270
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10270](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10270
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    78..91
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     gene            complement(1214..3091)
                     /gene="htpG"
                     /locus_tag="B6K89_RS00530"
                     /old_locus_tag="B6K89_00550"
     CDS             complement(1214..3091)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="htpG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391861.1"
                     /locus_tag="B6K89_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00550"
                     /product="molecular chaperone HtpG"
                     /protein_id="WP_163189150.1"
                     /transl_table=11
                     /translation="MAKKEFKAESKRLLDMMINSIYTQKEIFLRELISNSSDAIDKIYY
                     KALTDDALTFDKDSYYIKVAADKDARTLTISDTGIGMTKDELEQHLGTIAKSGSLAFKK
                     ENELKDGHDIIGQFGVGFYAAFMVADVVTVISKALGSEEAYKWESAGADGYTIEPCEKD
                     SVGTDIILKIKENTEDDSYDEFLEEYRLKAIIKKYSDFIRYPIKMDTTINKPKEGSENE
                     FEEVQEEQTVNSMVPIWRKNKSELTDEDYEKFYAEKHYGFDKPLTHVHISVDGAVRYNA
                     ILFVPDMPFDYYSKEYEKGLELYSNGVLIMNKCADLLPDHFSFVKGMVDSEDLSLNISR
                     EMLQHDRQLKLIAKNISKKIKSELQSLLKKDREKYETFYKSFGRQLKFGVYNDFGANKD
                     QLKDLLLFYSSKEKKLVSLDEYVSRMPEEQKYIYYATGDSYDRIEKLPQTEMVADKGYE
                     ILYFTEDIDEFAIKMLASYQEKEFKSVSSGDLGIDTDEDQKQSEEEENKYKDLFEEMKN
                     ILSDKVKNVRISKRLKSHPVCLAADGEVTIEMEKILNAMPDSQNVKAEKVLEINPNHEV
                     FQTLQDAFEQDKEKLSLYTNLLYNQALLIEGLPIQDPVEFTNNICKVMV"
     gene            complement(3259..3510)
                     /locus_tag="B6K89_RS00535"
                     /old_locus_tag="B6K89_00555"
     CDS             complement(3259..3510)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391862.1"
                     /locus_tag="B6K89_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00555"
                     /product="hypothetical protein"
                     /protein_id="WP_014481429.1"
                     /transl_table=11
                     /translation="MKVQHKKELKFYCFITIPSAFVVLTVISFLLQEITFPVTASAFLN
                     ASWHNLLFLIPFGLFFYPVHIWMKREFGRWNDTEKKRG"
     gene            3627..4448
                     /gene="yxbG"
                     /locus_tag="B6K89_RS00540"
                     /old_locus_tag="B6K89_00560"
     CDS             3627..4448
                     /NRPS_PKS="Domain: PKS_KR (7-160). E-value: 6.7e-09. Score:
                     27.8. Matches aSDomain:
                     nrpspksdomains_B6K89_RS00540_PKS_KR.1"
                     /codon_start=1
                     /gene="yxbG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391863.2"
                     /locus_tag="B6K89_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00560"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_160832095.1"
                     /sec_met_domain="adh_short (E-value: 2.1e-32, bitscore:
                     106.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.2e-38, bitscore:
                     125.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRLENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEE
                     TVDAIRKNGGQAESFHLDVSNENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYP
                     VDLFDRIIAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGIT
                     NLTRAMAIDYARNGIRVNSISPGTIETPLIDKLAGTKEQEMGEQFREANKWITPLGRLG
                     QPKEMATVALFLASDDSSYVTGEDITADGGIMAYTWPGKMLIDEKWKEETK"
     aSDomain        3648..4106
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6K89_RS00540_PKS_KR.1"
                     /evalue="6.70E-09"
                     /label="B6K89_RS00540_PKS_KR.1"
                     /locus_tag="B6K89_RS00540"
                     /protein_end="160"
                     /protein_start="7"
                     /score="27.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRK
                     NGGQAESFHLDVSNENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRI
                     IAVDLRGTFLCSKYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKG"
     CDS_motif       3654..3731
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_B6K89_RS00540_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="B6K89_RS00540"
                     /protein_end="35"
                     /protein_start="9"
                     /score="17.4"
                     /tool="antismash"
                     /translation="VITGAATGIGQATAEVFANEGARVII"
     gene            complement(4477..5619)
                     /gene="yxbF"
                     /locus_tag="B6K89_RS00545"
                     /old_locus_tag="B6K89_00565"
     CDS             complement(4477..5619)
                     /codon_start=1
                     /gene="yxbF"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391864.1"
                     /locus_tag="B6K89_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00565"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_163189151.1"
                     /transl_table=11
                     /translation="MPESAEAQVKEALLALLKERDIQHITMKEIAEKAKVSRGSLYLYY
                     EDKFSIIEDVIEDMKEGLGKALFDAFRHMDTLHLNKKRQTVHPTLSFVHEHRSFFSVMM
                     NRGHFHRFFKDVFQQDVLLAPIHVNLTPIERDIYGHYRALYTYAIILYWLNEDAAASPE
                     AISQKVWELVSQKRFYWLFGKAVPGEREKEKQIDRRVVRTREALQKALLDVLEEKKDYT
                     AITISDITRKSNIRRATFYDHYASKEELLQTMIQRSCAEIIDHLTIASSPNEFSLKEAE
                     KALASLLSALSNMPIVHFLNREWGVPHVIPDMFKALESFYLHQQTGIHAEKKLYAHYVS
                     AMIIGLLLYRLDEGKTHEPEVLAREFLQFLDVKKYKVVLL"
     gene            5761..7098
                     /gene="aldX"
                     /locus_tag="B6K89_RS00550"
                     /old_locus_tag="B6K89_00570"
     CDS             5761..7098
                     /codon_start=1
                     /gene="aldX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391865.2"
                     /locus_tag="B6K89_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00570"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_163189152.1"
                     /sec_met_domain="Aldedh (E-value: 3.6e-101, bitscore:
                     332.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQQVKDDIQRVFQLQKKQQKALRASTAEQRREKLQRFLDSVIAH
                     EEEIIEAIRKDVRKPYHEVKKAEIEGTKKAIRDNMNNLEQWMAPKEVGSSLSPDANGIL
                     MYEPKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFD
                     EKEVAIFEGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTI
                     IDSEYDLMDAAKKIAIGKFVNAGQTCIAPDYLFIKKDVQDRFAGILQTVVNAGFMEDDH
                     TPDRSKFTQIVNDRNFNRVKDLFDDAIEKGAEVVFGGVFDASDRTISPTVLKNVTPDMK
                     IMQEEIFAPILPMMNYEDIDEVIDYVNDRDKPLALYVFSKNQDLIDNVLQHTTSGNAAI
                     NDVVVHFSDVNLPFGGVNTSGIGSYHGVYGFKEFSHEKGVFIQAAE"
     gene            complement(7137..7616)
                     /gene="yxbD"
                     /locus_tag="B6K89_RS00555"
                     /old_locus_tag="B6K89_00575"
     CDS             complement(7137..7616)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="yxbD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391866.2"
                     /locus_tag="B6K89_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00575"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_003244176.1"
                     /transl_table=11
                     /translation="MNIIPTCQIPKDLVSAFFQKHWGSPQMVISSGIYNCDELDGYGML
                     NDDNQIVGLITYIFEEDACEIISLDSVIENKGIGTALLEKAEEACRERNIKQIKLITTN
                     DNIHALAFYQKRGYRLDRLFVNAVETARKMKPEIPLLADNKIPIRDELLLVKELQ"
     gene            complement(7696..8688)
                     /gene="yxbC"
                     /locus_tag="B6K89_RS00560"
                     /old_locus_tag="B6K89_00580"
     CDS             complement(7696..8688)
                     /GO_process="GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /gene="yxbC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391867.1"
                     /locus_tag="B6K89_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00580"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_003243554.1"
                     /transl_table=11
                     /translation="MSAVTESVLESIISPVTMSEFLEEYWPVKPLVARGEVERFTSIPG
                     FEKVRTLENVLAIYNNPVMVVGDAVIEESEGITDRFLVSPAEALEWYEKGAALEFDFTD
                     LFIPQVRRWIEKLKAELRLPAGTSSKAIVYAAKNGGGFKAHFDAYTNLIFQIQGEKTWK
                     LAKNENVSNPMQHYDLSEAPYYPDDLQSYWKGDPPKEDLPDAEIVNLTPGTMLYLPRGL
                     WHSTKSDQATLALNITFGQPAWLDLMLAALRKKLISDNRFRELAVNHQSLHESSKSELN
                     GYLESLIQTLSENAETLTPEQIFQSQDSDFDPYQSTQLVFRQLLTSYKF"
     misc_feature    8732..8745
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.23"
                     /tool="antismash"
     assembly_gap    8970..9010
                     /estimated_length=41
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     assembly_gap    9115..9171
                     /estimated_length=57
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            9267..10001
                     /gene="yxbB"
                     /locus_tag="B6K89_RS00565"
                     /old_locus_tag="B6K89_00585"
     CDS             9267..10001
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="yxbB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391868.1"
                     /locus_tag="B6K89_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00585"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_029318574.1"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     ADHEIESVTWMLTIEKEKEGAL"
     gene            10001..10270
                     /gene="yxbA"
                     /locus_tag="B6K89_RS00570"
                     /old_locus_tag="B6K89_00590"
     CDS             10001..10270
                     /codon_start=1
                     /gene="yxbA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391869.1"
                     /locus_tag="B6K89_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00590"
                     /product="PqqD family protein"
                     /protein_id="WP_033882790.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.8e-09, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.9e-12, bitscore: 41.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.4e-09,
                     bitscore: 31.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIEHEAIKVKQGA"
     aSDomain        10082..10252
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B6K89_RS00570_PqqD_RRE.1"
                     /evalue="4.30E-10"
                     /identifier="RREFam006.1"
                     /label="B6K89_RS00570"
                     /locus_tag="B6K89_RS00570"
                     /protein_end="84"
                     /protein_start="27"
                     /score="30.2"
                     /tool="antismash"
                     /translation="GITLNEMASDIYNHIDGKVSIHDICSKIVNEYDVDYQTCLEDCME
                     LFELLIEHEAIK"
     aSDomain        10088..10255
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B6K89_RS00570_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.70E-10"
                     /identifier="RREFam002.1"
                     /label="B6K89_RS00570"
                     /locus_tag="B6K89_RS00570"
                     /protein_end="85"
                     /protein_start="29"
                     /score="31.1"
                     /tool="antismash"
                     /translation="TLNEMASDIYNHIDGKVSIHDICSKIVNEYDVDYQTCLEDCMELF
                     ELLIEHEAIKV"
     gene            10274..10756
                     /locus_tag="B6K89_RS00575"
                     /old_locus_tag="B6K89_00595"
     CDS             10274..10756
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391870.1"
                     /locus_tag="B6K89_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00595"
                     /product="hypothetical protein"
                     /protein_id="WP_003243073.1"
                     /transl_table=11
                     /translation="MEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     gene            10777..13020
                     /gene="asnB"
                     /locus_tag="B6K89_RS00580"
                     /old_locus_tag="B6K89_00600"
     CDS             10777..13020
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391871.2"
                     /locus_tag="B6K89_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00600"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_163189153.1"
                     /sec_met_domain="GATase_7 (E-value: 2e-44, bitscore: 144.4,
                     seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-95, bitscore:
                     313.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYHENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSILRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETHSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     gene            13017..14216
                     /gene="yxaM"
                     /locus_tag="B6K89_RS00585"
                     /old_locus_tag="B6K89_00605"
     CDS             13017..14216
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yxaM"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391872.2"
                     /locus_tag="B6K89_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00605"
                     /product="MFS transporter"
                     /protein_id="WP_163189154.1"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIILNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALGGFTALVLLTLTIRIEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     gene            complement(14280..15512)
                     /gene="pgpK"
                     /locus_tag="B6K89_RS00590"
                     /old_locus_tag="B6K89_00610"
     CDS             complement(14280..15512)
                     /codon_start=1
                     /gene="pgpK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391873.2"
                     /locus_tag="B6K89_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00610"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_163189155.1"
                     /transl_table=11
                     /translation="MVKSFRMKALIAGAAVAAAVSAGAVSDVPAAKVFQPTAAYAAETV
                     FSQNNGASGFLTGRYDVQAMAPAMFNWSRESRFAGNTDGTLKWQNDIRTTPQNGAGAVI
                     DGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGTNGVIYLASYDKKIYFI
                     DKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKPTSKSTWTERWKMKTNG
                     VVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAFKGYPVIDKDGNIYAGN
                     QDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSGELFSISKNGDMNWSFY
                     TDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDSNVVSSPQLAEDGTLYI
                     GSYTKLMAFGK"
     misc_feature    complement(15546..15561)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.55"
                     /tool="antismash"
     gene            complement(15613..16038)
                     /gene="yxaJ"
                     /locus_tag="B6K89_RS00595"
                     /old_locus_tag="B6K89_00615"
     CDS             complement(15613..16038)
                     /codon_start=1
                     /gene="yxaJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391875.2"
                     /locus_tag="B6K89_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00615"
                     /product="DUF5391 family protein"
                     /protein_id="WP_163189156.1"
                     /transl_table=11
                     /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGISLAAAAVNVIWFVAAFRPGAENTSVNTLT"
     misc_feature    complement(16094..16107)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.05"
                     /tool="antismash"
     misc_feature    complement(16106..16119)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    16106..16120
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.73"
                     /tool="antismash"
     gene            16295..16750
                     /gene="yxaI"
                     /locus_tag="B6K89_RS00600"
                     /old_locus_tag="B6K89_00620"
     CDS             16295..16750
                     /codon_start=1
                     /gene="yxaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391876.1"
                     /locus_tag="B6K89_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00620"
                     /product="RDD family protein"
                     /protein_id="WP_015250840.1"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFVINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     gene            complement(16780..>17415)
                     /locus_tag="B6K89_RS00605"
                     /old_locus_tag="B6K89_00625"
                     /pseudo=""
     CDS             complement(16780..>17415)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391877.2"
                     /locus_tag="B6K89_RS00605"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00625"
                     /product="DUF418 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="YGSGSLKDIAEQRIHDRLVYMSSNGMLTYNPLNFFFASIPYFSMF
                     LLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDKEICLLIGAPFLMFF
                     YVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYHYGLGLYGKVYPAAG
                     VLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIVKKTKV"
     gene            <17416..18319
                     /locus_tag="B6K89_RS00610"
                     /old_locus_tag="B6K89_00630"
                     /pseudo=""
     CDS             <17416..18319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391880.2"
                     /locus_tag="B6K89_RS00610"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="B6K89_00630"
                     /product="SDR family oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VVAAARNEDALKELTDELKEKGHDAIWVKANVGKEEDVNRIAETD
                     RDQHIRPL"
     gene            complement(18378..18809)
                     /gene="yxaD"
                     /locus_tag="B6K89_RS00615"
                     /old_locus_tag="B6K89_00635"
     CDS             complement(18378..18809)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="yxaD"
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391881.1"
                     /locus_tag="B6K89_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00635"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_003243994.1"
                     /transl_table=11
                     /translation="MQNQNPVELIEYELTTFIRRAVYLDQSEKRTGNLERSSYLLLRQL
                     DEFGPARVKELAESFKLDISTLSRQAAALEAKELIYRFSDPSDGRVSLFTITKLGKQLL
                     KADQQKRLERYEQMLKEWSTQEKEMFGELLQRMNKAFID"
     gene            19036..19440
                     /gene="yxzK"
                     /locus_tag="B6K89_RS00620"
                     /old_locus_tag="B6K89_00640"
     CDS             19036..19440
                     /codon_start=1
                     /gene="yxzK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097798.1"
                     /locus_tag="B6K89_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00640"
                     /product="CidA/LrgA family holin-like protein"
                     /protein_id="WP_009968420.1"
                     /transl_table=11
                     /translation="MKVIRIILQVLILYVFFMIGEAIQHLFHLPVSGSIVGLVLLLICL
                     GLRIVPVSIIEDGAGFLLSFLPLLFIPAMTGVINYPSLISFNGLMLLITVVLSTIVTII
                     AAGFASQLLEKKAKKREEKEKCSKHVSRSL"
     gene            19410..20102
                     /gene="yxaC"
                     /locus_tag="B6K89_RS00625"
                     /old_locus_tag="B6K89_00645"
     CDS             19410..20102
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yxaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391882.3"
                     /locus_tag="B6K89_RS00625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6K89_00645"
                     /product="LrgB family protein"
                     /protein_id="WP_128422520.1"
                     /transl_table=11
                     /translation="MQQACIAIIIILLTVAAYLAMVKLYKRFPLPFLIPVLTTTILIVA
                     ALMMFHVSYEGYMIGGKWINSLLGPAVVALAYPLYKQWHIIVKHCIPILGGVLVGLCMG
                     MISGLIFAEAFGIDHDLLLSILPKSITTPVAIQIAAGLGGVPSMTVVFVMIAGFSGVIL
                     GPLFLKWLRIRSSLGQGIALGSASHALGTSKALEYGELAVSMSSVSMTLCAVLGSFFGP
                     LVVWLFHI"
ORIGIN
        1 gcaggagaaa ggttgtattt gtcctttcca tcattttcat tatcggtgcg ctcgcttgcg
       61 cgttttctca aacaatcggc atgctgattg catctagggt gatactcggg ttggccgtcg
      121 gcggttcaac ggcacttgtg cccgtgtatc tttccgaaat ggcaccgacg aaaattcgcg
      181 ggacactcgg cacaatgaac aacttaatga ttgtcaccgg gattttgctc gcctatatcg
      241 ttaactacct gttcacaccg tttgaagcgt ggcgctggat ggtcggtctg gccgcagtac
      301 ctgccgtgct tctattaatc ggcatcgcgt tcatgccgga atcgccaaga tggctcgtga
      361 agcgcggccg tgaagaagaa gcgagacgca tcatgaacat cactcatgac cccaaagaca
      421 ttgaaatgga attggcagag atgaagcaag gagaagcgga gaaaaaagaa acgacacttg
      481 gcgtgctgaa agccaaatgg attcgcccca tgcttctgat tggcgtcggc cttgccattt
      541 tccagcaggc ggtcggcatt aacacggtca tctactacgc gccaaccatt tttacgaagg
      601 ccggtcttgg cacatcagct tcggcgctcg gcacaatggg aatcggcatc ctcaacgtca
      661 tcatgtgtat cactgccatg atcttaattg accgtgtcgg ccgcaaaaaa cttctgatct
      721 ggggaagtat cggcatcaca ctgagccttg ccgctttatc aggcgtgctc ctaacgctcg
      781 gactttccgc atcaacagcg tggatgacag tagtctttct aggtgtctat atcgtctttt
      841 accaggcgac atggggtccg gtagtgtggg tgctcatgcc tgagctcttc ccgtccaaag
      901 cacgcggagc cgcgacaggg ttcacgactt tggtgttatc ggcggccaat ctgatcgtgt
      961 cgctcgtctt cccgctgatg ctaagcgcga tgggcatcgc atgggtcttt atggttttct
     1021 cagtcatttg tcttctctca tttttcttcg cgttctacat ggtaccggaa accaaaggga
     1081 aaagcttgga ggaaattgaa gcaagcctga aaaaacggtt taaaaagaag aaaagcaccc
     1141 aaaaccaagt gctgaatgag cgtacattat aaaaaaagga atcgtctcct tatgggacga
     1201 ttcctttttc tgtttacacc atgaccttgc aaatattgtt cgtaaattcc acagggtcct
     1261 gaatcggcag gccttcgatg agaagcgcct gattgtacag aaggtttgtg tacaggctca
     1321 gcttctcttt atcttgttca aacgcgtcct gcagcgtttg gaatacctcg tgattcgggt
     1381 tgatttccag cactttttcc gccttcacat tttggctgtc aggcatcgcg tttaagattt
     1441 tttccatctc aattgtcact tcgccgtcag cagcaaggca gactggatgt gatttaagcc
     1501 gttttgagat tctgacgttt ttcactttgt ctgacagaat gtttttcatt tcctcaaaca
     1561 gatccttata cttgttttcc tcttcctcgg actgcttttg atcctcatcc gtgtctatgc
     1621 caaggtctcc gcttgatacg gacttgaatt ctttttcctg ataagaagcc agcattttaa
     1681 ttgcaaactc atcgatgtcc tcagtaaagt agaggatttc atagcctttg tccgccacca
     1741 tttccgtttg cggcagtttc tcaatgcggt cgtaagaatc accggtcgcg taataaatgt
     1801 atttctgctc ctcaggcatt ctggaaacat actcgtctaa gctgaccagt tttttctctt
     1861 ttgaagagta gaataatagg agatccttca attgatcctt attcgcgcca aaatcattgt
     1921 acacgccgaa tttcagctgt ctgccgaacg acttgtagaa cgtctcgtat ttctcgcggt
     1981 cttttttcaa caggctttgc agctcgcttt tgattttctt gctgatgttt ttcgcgatca
     2041 gcttcagctg gcggtcatgc tgcagcattt ctctggaaat attcagcgat agatcctcag
     2101 aatcgaccat gcccttcaca aagctgaagt ggtccggtag caggtctgcg cacttattca
     2161 tgatcagcac gccattggaa tacagctcca agcctttctc atattccttg gaatagtagt
     2221 caaacggcat gtcagggacg aatagaatcg cgttgtagcg aaccgctcca tccacgctga
     2281 tatgaacgtg tgtcagcggt ttatcaaacc cgtaatgctt ttcagcatag aatttttcat
     2341 aatcctcatc tgtcagctcg cttttgtttt ttctccagat cggcaccatg ctgttgaccg
     2401 tctgctcttc ctgcacctct tcaaattcat tttcgctgcc ttccttcggc ttattaatgg
     2461 ttgtatccat tttgatcggg tagcgaatga agtcggagta cttcttgatg atcgctttta
     2521 aacgatattc ctctaaaaac tcgtcatagc tatcatcttc tgtgttctct ttgattttca
     2581 ggataatgtc tgtaccgaca gaatcctttt cacacggttc aatcgtatag ccgtctgcac
     2641 ccgcagactc ccatttataa gcttcttcgc tgccaagcgc tttactgatg actgtcacga
     2701 catcggcaac cataaatgcc gcgtaaaaac cgacaccgaa ctgcccgata atgtcatgtc
     2761 cgtctttcag ctcgttttcc tttttaaacg cgagggaacc gctttttgca attgttccaa
     2821 gatgctgttc aagctcatcc tttgtcattc cgatccccgt atcagagatg gttaatgttc
     2881 tcgcatcttt gtcagctgcg acctttatgt agtaactgtc tttatcaaac gtaagcgcat
     2941 cgtccgtaag cgctttgtaa tagattttgt caatcgcatc actcgaattg gagattaact
     3001 cgcgcaggaa aatttctttt tgggtataaa tggagttaat catcatatcc agcaagcgtt
     3061 tagactctgc tttaaactct tttttcgcca ctcttgatcg ctcctttacc attatgtaaa
     3121 cccttttcag catctattta tcacataaga tgacaattgt caattagatt gatagatgca
     3181 tatatatgta aatttaacat tagttggatt tgttttcact ctttttctca ctcattctca
     3241 taaaaaagag aggcttcatc atcctctctt tttttctgtg tcattccagc ggccaaactc
     3301 ccgcttcatc catatatgca ccgggtagaa aaacaaaccg aacggtatca aaaacaatag
     3361 attatgccat gaagcattca gaaatgcgct tgcagtcacc ggaaacgtaa tctcttgcaa
     3421 taaaaaagag atgacagtca gcacaacaaa tgcagatgga atggtaatga agcaataaaa
     3481 cttgagctcc ttcttatgct gtaccttcaa acatacaaac ctcccaacaa tttctaattc
     3541 atcttaacat atgctggcct ttcttttctc gcatgtttat cactgcacat agcgggaaga
     3601 caaatagaaa aaggaggtct cgtatcatgg gaagacttga aaacaaaaca gcagtgatca
     3661 caggcgccgc gacaggcatt gggcaagcga cggcagaggt ttttgccaat gaaggcgcgc
     3721 gtgtgatcat cggagatatc aataaagatc aaatggaaga aacagttgac gcaatcagaa
     3781 aaaacggagg acaggccgaa tcctttcacc tcgatgtgtc aaatgaaaac agtgtgaaag
     3841 catttgctga tcaaatcaag gatgcatgcg gaacgattga tatactgttt aataatgccg
     3901 gcgttgatca ggaaggcgga aaggtgcacg aatatccggt tgacctgttt gaccgcatta
     3961 tcgccgtcga cctgcgcggc acattccttt gcagcaaata tctgattccg ctcatgctcg
     4021 aaaatggagg ctccatcatc aacacctcct ccatgtcagg ccgggccgcg gatctcgacc
     4081 gctccggcta caatgctgca aaaggcggga tcacgaacct gactagagcg atggcgattg
     4141 attacgctcg aaacggcatc cgcgtcaatt ctatctcacc gggcacgatc gaaacaccgc
     4201 tgattgataa actggcaggc acaaaagaac aggaaatggg cgaacaattc cgcgaagcca
     4261 acaaatggat cacgccgctc ggacgtcttg gccagcccaa agaaatggca acagtggcac
     4321 tgttcctcgc atcagacgac agctcatacg tcacaggaga agacatcacc gcagacggcg
     4381 gcatcatggc gtacacatgg cctgggaaga tgctgattga tgagaaatgg aaggaagaaa
     4441 cgaaataaga gagggagccc cctctctttt tgtcttttaa agcaatacaa ccttatattt
     4501 cttcacatcc aaaaactgca aaaactccct cgccagcact tctggctcat gcgtctttcc
     4561 ttcatccagc cgatacaaaa gcaacccgat aatcattgcg gatacataat gggcataaag
     4621 ctttttctct gcgtgaatac cagtttgctg atgcagataa aacgattcca gcgctttgaa
     4681 catatcaggt atcacatgag gaacacccca ttcccgattg agaaaatgga caatgggcat
     4741 gtttgacaaa gcagaaagca gactggcgag cgccttctcc gcttccttta aggaaaattc
     4801 attcgggctg gaggcaatcg tcaggtgatc aatgatctcc gcacatgatc gctgtatcat
     4861 ggtttggagc agttcctctt tactggcata gtgatcataa aaggttgcac ggcggatatt
     4921 gcttttccgg gtaatgtcag aaatcgtgat ggccgtgtag tcttttttct cctccaacac
     4981 gtccagcaaa gccttctgca gcgcctctct cgttcgaacc acccgcctgt cgatttgctt
     5041 ctccttctct cgctctcctg gcacagcttt tccaaacagc caataaaacc gcttttgaga
     5101 aacaagctcc cataccttct ggctgatggc ttcaggagac gcggccgcat cctcattcag
     5161 ccaatacagg ataatcgcgt acgtgtacaa ggcccgataa tgtccataaa tgtcccgttc
     5221 aatcggcgtt aaattcacat ggatcggagc cagcagcaca tcctgctgaa acacatcctt
     5281 aaaaaaacga tgaaaatgtc ctctgttcat catcacagaa aaaaaggatc gatgctcatg
     5341 aacaaaggac agcgtcggat gcaccgtttg ccgttttttg ttcaaatgaa gggtatccat
     5401 atgtctgaag gcgtcaaaaa gcgctttgcc cagtccttcc ttcatatctt cgatcacatc
     5461 ctcaatgatt gaaaacttat cctcataata aaggtagagc gatccgcggc tcactttggc
     5521 cttctcagcg atttctttca ttgtgatgtg ttgaatatct ctttctttca ataaagccag
     5581 cagcgcctct ttcacttgag cttcggcaga ttccggcaca aaagacaccc ccaatcatta
     5641 gacaaatgtt cgatatatgt acggtaacgt atagatggtt caccgttgtc tttcttacag
     5701 aaaaggtacc actttataat aggtccgaga taagaagaaa gcaaatgagg gggatttaca
     5761 atggaacagc aagtaaagga cgacattcag cgcgtttttc agcttcagaa aaaacagcaa
     5821 aaagcattgc gcgcttcaac agcggaacag cggagagaaa agcttcaacg ctttttagat
     5881 tccgtcatcg cccatgaaga agaaatcatc gaagcgatcc gcaaagacgt ccgcaaacca
     5941 tatcacgaag tcaaaaaagc ggaaatcgaa ggaacaaaaa aagcgattag agataatatg
     6001 aataacctgg aacaatggat ggcgcctaaa gaagtcggtt catcgttaag ccctgacgca
     6061 aacggaattc ttatgtacga gcctaaaggc gtcacactca tcctcggccc gtggaactat
     6121 ccgtttatgc tgacgatggc gccgcttgcc gcttctctcg cagccggaaa cagcgcgatt
     6181 gtgaagctgt ccgatttcac gatgaacacg agcaacattg ccgctaaagt gataagagac
     6241 gcttttgatg aaaaagaagt cgcgattttt gaaggagagg ttgaggtggc aaccgaacta
     6301 cttgatcagc cgttcgacca tattttcttc actggaagca caaatgtcgg gaaaatcgtc
     6361 atgacagcgg ctgccaaaca cttggcatct gtcacacttg agcttggcgg caagagcccg
     6421 acgattattg acagtgaata cgatctgatg gacgcagcga aaaagatcgc catcgggaaa
     6481 ttcgtaaacg ccggccaaac ctgcatcgca cctgattacc tgttcattaa aaaagacgtt
     6541 caggacaggt tcgcggggat tttacaaaca gtcgtcaacg ctggatttat ggaggatgat
     6601 cataccccag accgcagcaa atttacgcag atcgtcaatg accgcaactt caaccgcgtc
     6661 aaagatctgt tcgacgatgc catcgaaaaa ggggcggaag tggtgttcgg cggcgtattc
     6721 gatgccagcg accgcacgat ctcgccaacc gttttgaaaa acgtcacgcc tgacatgaaa
     6781 atcatgcagg aggaaatctt cgcaccgatc ctgccaatga tgaactatga agacatcgac
     6841 gaggtcatcg attacgtaaa tgaccgcgat aaaccgcttg cactttatgt gttcagcaaa
     6901 aaccaagacc tgattgacaa cgtccttcag cacacgacat caggaaatgc cgccatcaat
     6961 gatgtcgtcg tccatttcag tgacgtcaac ctgccattcg gcggcgtcaa cacaagcgga
     7021 atcggctcct atcatggggt atacggattc aaagagtttt ctcatgagaa gggtgtattt
     7081 attcaggccg ctgaataatc gcatgatcaa aaggcgcttc cttagaggag cgccttttat
     7141 tgtaactcct tgaccaaaag caattcatca cggataggta ttttattatc tgccagtaaa
     7201 ggaatttcgg gcttcatctt tctggccgtc tcgactgcat tcacaaatag tcgatccaac
     7261 cggtaccctc tcttctgata aaacgctaat gcatgaatat tatcattggt tgtgatcagt
     7321 tttatttgtt tgatatttct ctctctgcat gcttcctcgg ctttctctag cagagctgtt
     7381 ccgatccctt tattctcaat gacactatcc agcgaaatga tttcacaggc atcttcttca
     7441 aatatgtatg taataaggcc aacaatctgg ttatcatcgt tgagcattcc ataaccatct
     7501 aattcatcgc agttataaat accgctagaa ataaccattt gcggactgcc ccagtgtttt
     7561 tgaaaaaacg cggaaacaag atctttaggt atctggcatg tcggaataat attcatattt
     7621 tcctcctttt agctgaacaa aaataagaga attaacaacc tattttatgt cattaatccc
     7681 cttatctagt atttactaga acttataact tgtcaaaagc tgtctgaata ccaattgcgt
     7741 ggattgataa ggatcaaaat ctgaatcctg agattggaag atttgctctg gggtcaatgt
     7801 ctctgcgttc tctgataacg tttgaatcag actttccaaa tatccattta actctgattt
     7861 ggacgattca tgtagggatt gatgatttac agcgagttct ctaaatctgt tatcactgat
     7921 taattttttt cgaagagctg ctagcatcaa gtcaagccat gcaggctggc caaatgtaat
     7981 atttaaagct aacgttgctt gatcagattt ggtggagtgc cataaacctc ttggcaaata
     8041 cagcatggtt cccggtgtta aattaacgat ttctgcatct ggcagatcct cttttggcgg
     8101 atctcctttc caatatgact gtaaatcatc aggatagtaa ggagcctctg ataaatcata
     8161 gtgctgcatt ggattgctca cattttcatt cttggcaagc ttccatgttt tctcaccttg
     8221 aatttgaaaa atcaagttgg tgtaggcgtc aaaatgggct ttgaatcccc cgccattttt
     8281 cgccgcgtaa acaatggctt tggaagaagt acccgcaggc agtcttaatt ccgctttgag
     8341 tttttctatc caccttctga cttggggaat aaataggtcg gtgaaatcaa actctaatgc
     8401 agcccctttt tcataccact ctaaagcctc tgcaggtgac acaagaaatc tgtctgtgat
     8461 cccttcagat tcttcaatca cagcatcacc aacgaccatg actggattat tgtagatagc
     8521 caatacgttt tctagcgttc taaccttttc aaaccccggt atgcttgtaa atctctccac
     8581 ttctcctctg gctaccaaag gttttacagg ccaatattct tctaaaaact cactcatcgt
     8641 tacaggactg atgatagact ccaaaaccga ttcggttaca gcactcatat tatccctccc
     8701 aaaaaaagta acttcatcac aaagatataa catttttttc taaaagtaaa tattgacaga
     8761 attatcagag gattataata tttagttgtg cgtgatagcc tattttttta caatgaagga
     8821 gggaacagga tgaaaaaggc ttataagaaa cctcgtcttt ttgaactacg ccgtgctgta
     8881 gcagctggcg gccattaatc tcatatagca tttgacatct agtactctat tttaggaggg
     8941 atgctcaatg aaaaaagctt ataagaaacn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9001 nnnnnnnnnn ctgcgccgtg ctgtagcagc tggcggccat taatctcata tagcatttga
     9061 catctagtac tctattttag gagggatgct caatgaaaaa agcttataag aaacnnnnnn
     9121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nttgcgccgc
     9181 gctgtagcag ctggcggtca ttaatcttat ccaaaacgat taacgtttga ggctatcacg
     9241 ccaacttgat aaggaggatg ctgaagatga ttacggctga agaatgcaga acgtacaaag
     9301 aatttgttga tctttaccaa tcctatcttt accccttgct tggcgccaga ctgtcccgga
     9361 tgtattcccc caaaaacaaa gtcattatcg atatgggcac aggtccaggt tatttaagca
     9421 ttcagttggc taaaagaaca aatgcgcacg tgcatgctgt cgatattaac ccggccatgc
     9481 atgaaatcgc tcaagaagaa gctaaaaaaa gcggagtaag tagcctgatt tcatttgatt
     9541 tggaagatgt ccaccattta tcttacgctg accaatatgc tgacttcatc gtctcctact
     9601 cttgcctgca tcattgggaa gacgttgtta aaggacttaa agagtgctat agagttctgg
     9661 ctccgggcgg aaaaattgtc attttggata catttaatcc ccaaggaagc catttagaga
     9721 ttatgcgaaa acaaatcaaa gaaccggaat acttcaggtt tgtaagagag gcatttgaag
     9781 aaagttattc ctttgaagac attcaccagt ttgttcagga tgccggcatt cccaattatt
     9841 cattagaaac ctttcacttt ttaccggagg attttataga aagcttagat gagctggagg
     9901 atgctcccct gtgggaacaa aatgatcaaa gcgctgatca tgaaattgag tctgtcacat
     9961 ggatgttaac gatagaaaaa gaaaaggaag gtgcattgta atgatcaatg aatcaactgt
    10021 tttatccaaa aatccagaaa tgccatcaag aaaatatttg aaaagcatta ttatagagcc
    10081 gggcatcact ttaaatgaaa tggcatcaga tatttataac catatcgacg gcaaggtcag
    10141 catacatgat atttgctcaa aaatcgtcaa tgaatatgat gttgattatc aaacctgctt
    10201 agaagattgt atggagctgt ttgagttgct tattgaacat gaagcaatca aagttaagca
    10261 gggggcatga gaattggaaa aacaaaaagt gcttgcttta ccagacgatg tacatgagct
    10321 gagtacacac cgttctaaat caatcgtaaa ttacatcatc actctgcttg cctttgccaa
    10381 aaaacaagga ttgactcatc aagatattgt aagctggatt cacgagcaat atgaggaaag
    10441 aggatattat gatgagtgga gacacattaa cagccaacaa ccagttggat catttgtgga
    10501 actctttata aaaggaagac gtttacttta tgacaaaatt gaattgtttg aaacagaaga
    10561 taaatatgtc gtaaataccc acacttggta tgaaaaagaa cctagtgagg ccttttttta
    10621 ttttgaaatt gatcccgaag aattttctgc gtacgcttcc attctcgcaa tcgaaaacgc
    10681 aaaacgtctc ggaattaaaa tcgatattgt aaaagaaaca gatgtagaga cagcttatat
    10741 ctataaacat caataacgct attgggaggg agacatatgt gcgggctcgc gggtattata
    10801 aatctggctg ctccccgttc tcaggaatgt acctttcata tattgaaagg catggcagat
    10861 gccatcagct ataggggacc ggatgatgaa caatatcata ttgattccaa agtcggcttt
    10921 gcatttcggc gattgtccat tcttgacctt gtaaatggac agcagccctt tttaaatgag
    10981 gatggatcaa tcgtcgttat ggtaaatgga gaaatttata actataaaga actgaaggct
    11041 tctttacaca atcatatgtt taaaacgaca tctgattgtg aagtaattgt tcatttatat
    11101 gaagaaaaag ggattggatt tgtagacgac atcatcggaa tgttttcaat agccatttgg
    11161 gacaaaaata aaaacaaagt atttttagtt cgtgaccgct ttgggattaa accgcttttt
    11221 tacacagagc taaaacacga gcttatattt gcctctgaaa taaaatccct attttctcat
    11281 cctcactgtc cccgccaatt taattggaaa gaagcactct cagacatttg gctaagcggg
    11341 gaagcagcca gtaatcataa agaaaccact tccttttttg taaacatcca aaatctcgat
    11401 gctggccatt atctcgaaat taatttgaca acaaatgaac gaaaaacagc aagctattgg
    11461 tctttacagg atattttgct caggcaaggc tatcatgaga atctccatcc cgatgacctg
    11521 attgaaggat atagagaact gctggcagat tcagtccata gatgtttaca aagcgacgtt
    11581 gaagtcgggt tgtttcttag cggtggcatt gattcagctg cagtcgcaca ttttgctgca
    11641 gaaaaacagg atctccatac gtttacagta ttaagccaaa gtacatttac aaatgaagat
    11701 gctaaatatg cccattggct ggctaaagat ttacaccttc caaatcatca ggttctctat
    11761 caattaggga acgatgagtt attacaacca gagtcatata aacatttgtt atggatctgt
    11821 gaaacaccgt tttgcggacc ggaacaatta tataagtttc atttacataa gtatgccaaa
    11881 gcgataaggc caaacctgaa agtcatgctg accggccagg gcagcgacga atttaacggc
    11941 ggttacagca cgacactttc accagccgag aacccaagtt gggaaggatt tattgaatcg
    12001 gtcaatacga tggagatgaa ccggctgcat cggctgcagg gaaatatctt tagagtgtgg
    12061 gaggagcatt ttggactttc tcctataaac ctttcttatt taaagagcaa tgattccagc
    12121 caagcagatc cttggcaatc gtatgtcctg acaaaatacc gtgacctgca aatgtataat
    12181 tgctggcatg aagatcggat cgccgcggct aatcatatcg aaaaccgtgt accgttcttg
    12241 gaccatcggc ttgttgaatg ggtttgcgga atacctgatg gactccgtaa agacttgtta
    12301 tgggataagt cgatattgcg aaaatcatta acaaatgagc tgcatacaag ctatacccac
    12361 cggccaaagg ttcctttttt ctatggtaag gacgtgagat atacacataa aatgatgttt
    12421 catcttctga agaaaaacaa ttatcagctt atagaggagg ccttctctca cagcgatgcc
    12481 tccagcataa tacaggttga acacattcat gccatcatga catatttgga ggacgatcct
    12541 gagtttacaa attttgaatt tttattaaga ctggtgaaca tgggactttt atcaaaaatg
    12601 actaaagaaa cccattctgt tcaattagac ataaccagcc atttagaatc gataacaata
    12661 aaagactggc actcacagga aggtgatatt gccagccgtt taaatatctc agccaataag
    12721 tgtgaaggac aagatatttt ggcgctaaac cctggcgtca ctctgttaag gccggaaagc
    12781 gatagtgagc attgcatcta cattgcggaa gaaggattta ttcagtttat tgtttcggag
    12841 gaagacgtcg gagcttggct gcatattctc tgcgatatta atggaaaaga cacacttcat
    12901 acgattttag acagacatgg tgtcagcctt gaagaagtgg ccaaatatat tcaagaagcc
    12961 atcgaacaca atatcatttt gatcaaacaa aaaaatctgc cagaaggagc atatagatga
    13021 gcatctttta ttcgttttcc gcacttaggg gattagcaat ggggattttt tcgcctattt
    13081 ggattcttta tctgatatct aaagattatg atttccttca gattggatta atgggagcgg
    13141 tacttgaaat tgctaagctt atatttgaag ttccttccgg cgtttttgct gatcgttatg
    13201 gaattaaaat ttcaattgcc agttcattct ttttctccat ccttacatgg gccttcttcc
    13261 cttttatcga ttcagctgct atttgcatac tggctatgat catatgggct ttatcagatt
    13321 ccttaatttc cggttctttt gaaacttgga tgagccgtgt cgcaggggaa gatcgattcg
    13381 gcaaagaaat gatgaaaaac acacaattgc taatcacttt tttaattatt ggaagtattg
    13441 ccagcgggta tttgtattca ttaaatatct attttccttt cctgctcgtt atggtgatct
    13501 acttattact atttatttgg atgtctgtat ttattaaagt cccttctgtt tccgaaacaa
    13561 atcatgggga tcagaaccaa catgattcga taaagattat caaagaaagt ttaaaaatta
    13621 tccttaacaa aaaaagggtt cttttaatcg tcatagccgg tttctttaca gccacagcct
    13681 atgacacaat ttcccgttac tggcagcctt ttttgagtga tttaggcttt tcagaaaagt
    13741 cactgggata tatttttgcc ctaggagggt ttaccgctct cgttcttttg acattaacca
    13801 tcaggatcga aaagaagatc gaaaaaaatc catatctcgc tttaacctca ttggattcca
    13861 tgggcatggt catgactttt ctattgtcta gagcattcag gccgctgggc attccatgta
    13921 cagcgttttt gcttgcaatt gaagatattc atcatccgat cgtaacaagt tacttaaata
    13981 agtttttccc cgattcatac aagaacacac ttttctcgtt aaactcaggg gtaggagcaa
    14041 ttggagaaat tctttccggt gtcattttcg gcatcatttc cgcagccttt gggctctctg
    14101 ccatgtttgt tgttgtagct gtatttctat taatccctat tatcctttat acgatagtgc
    14161 ctaagattaa agacaatgat atgaaagttc agattgaaaa atcccagcaa gtgtaaatgt
    14221 tttgtatcac agtaagaaga ccttcttatt aaaagaaggt cttccgctat tctattcagt
    14281 tatttcccaa aagccatcag cttcgtataa cttccaatat aaagtgttcc gtcctcagcg
    14341 agctgaggag aagacacgac gttgctgtcg gtttgatagc tccataattc attgccgttt
    14401 gcgtctgccg cataaacctt catatcatct gacccgaaat aaaccgttcc cttcgcgtca
    14461 atcagcggcg ccgttctgac agggccgtct gtatagaatg accagttcat atccccgttt
    14521 ttgctgatgg aaaacagctc gccgcttcct gagccgatgt agatattgcc attatgatca
    14581 atcgcaggag atgagctgga gaacccgttt agcgggaatg tccatttcaa actgcctgtt
    14641 gatgtataag catacagctg tccatcttgg ttgccggcat aaatgtttcc gtccttatca
    14701 atcaccggat atcctttaaa cgcatttgac gtcgttctgg accatttcac ctgtccggtt
    14761 ccggagttga tcgcataaaa cacgtaatta tatgtgccga catacacggt gccgtttttg
    14821 gcaagcaccg gcacagagct gacgacacca tttgttttca tcttccagcg ctctgtccaa
    14881 gttgattttg acgtcggttt gatcgcgtga acataattat caagtgttga gaaatacaac
    14941 gtcccgtctg aaccgatcac cgtttcagag cttggcccgc cgcttaacgg aaccgttgtt
    15001 aaaatttctc ccgtttcttt gtcaataaaa taaatctttt tgtcatagga tgccaaatag
    15061 ataacgccgt tggtcccaag tacaggagat tgcgtatatg tttttccaag attgcccgtc
    15121 acccatttga ctgagccgtc tggattaaag gctttcattt ccccgtctct ggaatgaaga
    15181 tatactgtgc cgtctccgtc aatcacagcc cccgctccat tttgcggagt cgttctgatg
    15241 tcgttttgcc atttcagcgt cccgtctgta tttccggcga accggctttc gcgtgaccag
    15301 ttaaacatgg caggcgccat cgcttgtaca tcatatcttc ctgtcaaaaa gccagatgct
    15361 ccattatttt gagaaaatac cgtttccgcc gcataagcag ctgtcggctg aaacactttg
    15421 gcagcgggca catcagaaac agcaccggcc gaaacagccg ccgccaccgc agctcccgca
    15481 atcaaagctt tcatacgaaa tgacttgacc atcattgaga cccccattat atgtaacttc
    15541 taatttgtga ccatcataac atattcatcc attttataaa tctatttcac aaaaacatca
    15601 caaactagaa aactatgtaa gagtattcac ggacgtattt tcagcacccg gccgaaatgc
    15661 agccacaaac caaatgacgt tgacagcagc cgcagcgaga ctaattccca aaacaaagat
    15721 cacctcagaa agcagatggt cactaaagaa actaaacatc aagataaaac cggccgaaga
    15781 caaatgaatc aaaagtccga agccgcaaag caccgccatg acatacctca ttgcatcgac
    15841 tccgagcata taaacgagaa atggaatgaa atacaagaca aggatcatac cgacagctga
    15901 ccacatgcca gctgaattaa actgattggc cgccgctccc gttccggcca gcggcgaaag
    15961 tgaagccgcc acaatcacgg cgcaaaaaag aaacgcagaa atggttgtca tgatcgccac
    16021 gctatttttt ttagacatca aactcctcct ttaatagaaa tattaacctt ttttattata
    16081 agtaagttga atgttatatt cattatattt ttaaaaaatt ccagaataca tacacaattg
    16141 ctatgcttct ttctagtata tttatatagt aaaaaacaaa ggataaaaga ctcatttttc
    16201 tgtaatatca ggattttatc accataccat attgcatgta cttgtttttc aaagtatact
    16261 attccagatt aattcagagg agagagaaaa atacatggaa aaaccagcag gattttggat
    16321 tcgtttttta gcttatttta ttgatggcat tattgtatct gttcctagtt atattattct
    16381 atttgtgatc aattctgttt ttgtagctgg ggctgtggca acaaaccctt acatgacgga
    16441 agaagagtat ttagtgaaat acatgacgct tgcatttttg cctactatgc tgatcatgat
    16501 cgtcatcagc gtattatatt acgggctgct cacggcttct aaaatgcaag gcacacttgg
    16561 caaaaaaatt cttggcctga aagtggtcaa tgaacaaggc gaacgggttt ctgtcggaca
    16621 gggaattggc cgttactttg cctatatctt atctggaatc atcttttata tcgggtttat
    16681 catgatcgcc tttggagaga aaaaaggcct gcatgacatc atttgcaaaa cacgtgtcgt
    16741 gtataaataa tagaaaaaag tctagacgcc aataggcatc tagacttttg ttttctttac
    16801 aataggctgc cacgacagat acgtagcgct tctccacagc cactcaaacg gccccatccg
    16861 aaagacacga agccaaaggt ggctgaagac catttgaacg gcacaaacag caattgtaat
    16921 gagcacgccc gcagcagggt acacttttcc atacaggccc aagccgtaat gataaaaaat
    16981 ccaagtgcac acaatagact gcatcaaata attggtaaat gccatcctcc caacagcgga
    17041 gaatgattgc agcactgttc tcactcttgt tttatgataa agatagacaa ccgttgtaac
    17101 atagaaaaac atgaggaaag gcgcgccaat cagcaaacat atttctttat ccgttacact
    17161 gtacagcacc tgggcgccga tgccgatgac aagcccagcc atccacaatc gttttaatcc
    17221 tttgcgatgc ttttccggtt catgcaagta ccgagatttc gctgccgcag ctcccagcaa
    17281 aaacatgctg aaatatggaa tggatgcaaa gaagaagttg agcggattat acgtaagcat
    17341 gccattcgaa gacatgtaaa caagacggtc gtggatccgc tgttctgcaa tgtccttcag
    17401 gctgccgctt ccatagtcgt ggcagcagcg cgaaatgaag acgcgctgaa ggagctcact
    17461 gatgaactta aggaaaaagg gcacgacgcc atatgggtaa aggcgaatgt cggaaaagaa
    17521 gaggacgtca accgcatcgc agaaaccgac cgcgatcagc acattcggcc gctttgacac
    17581 atgggtcaac aatgcggccg tctcgacttt cggacatgcc atggacgtca ccgtcgaaga
    17641 catgaagcgc atgttcgaca caaatttctg gggacctgtt tacggaacaa gtgcggctgt
    17701 caaacactac accggcagag gtgtgccggg cgcactcatt aatgtaggaa gcctgttcgg
    17761 agacagggga acagtcattc aatccacata tgcgtctgcc aaatttgcgc ttcacggctg
    17821 gacggaaagc atccgaatgg agcttgaaaa ggaacaggcg cccgtctcgg taacgctcat
    17881 ccacccgggc agaattgaca caccatataa cgagcatgcg cacagctacc tcgacaaaca
    17941 gccggctcat taccgctcca tgatctatcc gccggaagcg gtcgccgaag ctatcctgtt
    18001 tgccgccgaa caccctaagc gcgacatgta catcggctca caggccaaag ccatcgccat
    18061 gctgggcgcg ctttttcctc gtctgaccga cagactgatg gaaaaaatca tgtatcacag
    18121 ccagcatgcc gaaagaccgt ccaaaccgcg agaagaaagc gctctttatg atgagggctg
    18181 cggtatgcat gacagaggca caaataaagg atggatgagg tcaagaagct actacacaaa
    18241 agcgacgaag cgccccattg tatcggcggc tgttgttgcc ggactagtgg cttgggctgc
    18301 cgccaaacga tgcagataat ctctgaccat gatagaaaaa cccatgctgt tccagcgaac
    18361 catgggtttt ttagctgtta atcgataaaa gccttgttca tacgctgcag cagctcgccg
    18421 aacatctctt tttcctgtgt tgaccattct ttcagcatct gttcataacg ttcaaggcgc
    18481 ttttgctgat cggcttttaa tagttgtttg ccgagttttg taatggtaaa caggctgact
    18541 ctcccatcag acgggtctga gaaacgatag atgagctcct ttgcctctaa tgcagctgct
    18601 tgtcttgaaa gagtagaaat atcaagctta aacgattctg ccaattcctt aacacgagca
    18661 ggcccaaact catccaattg tctcagtaat aagtacgaag atctctccaa attccctgtt
    18721 cttttctctg attgatccag ataaacagct ctcctgataa aagtcgtcag ctcatattca
    18781 attaattcaa ctggattttg attttgcaat cgctctcgct ccctattcca atctccggca
    18841 ttgacaacat catatatact tgtataatac aaatgtacat taacttaata aatacaagtc
    18901 gttatatgac taaatcaatt attatacttg tatagtacaa tcatataaaa agaaagtaaa
    18961 gcgattcctc agaaccatcc tagaagcaag caccagaaag gaggaagctg ttctgattgg
    19021 agagcagcac ttgatgtgaa agtcatacga attattttgc aagtgttgat attatatgta
    19081 ttttttatga tcggggaagc cattcagcat ctgtttcatt tacccgtgtc aggaagcatc
    19141 gttggattgg tattgcttct gatctgcttg ggcctccgta ttgttcccgt ctccatcatt
    19201 gaagacggag cagggttttt attatccttc cttccattgt tgttcatccc ggcaatgaca
    19261 ggagtgataa actatccgtc tctcatttca ttcaatggcc tgatgctgct gattacagtc
    19321 gttctgagca ccatcgtcac gatcattgcg gctggattcg ccagccagct attagagaaa
    19381 aaagctaaaa aacgggagga gaaagagaaa tgcagcaagc atgtatcgcg atcattataa
    19441 ttcttttaac agttgccgct tatttagcga tggtcaaact ctataagcga ttcccgcttc
    19501 catttctgat ccctgttctg acaacgacca ttttgattgt agcggctttg atgatgtttc
    19561 atgtttccta tgaaggctat atgatcgggg ggaaatggat caattctttg cttgggccgg
    19621 ctgtcgtggc actggcctat ccgctttata aacaatggca tatcattgtc aaacattgta
    19681 ttcccatttt aggcggcgtc ctggtcggat tatgcatggg aatgatcagc gggctgatct
    19741 tcgcagaagc attcgggatt gatcatgatc tcttattatc cattctgcca aagtcgatca
    19801 caacccctgt cgctattcag atcgccgccg gtcttggcgg cgtcccttcc atgacagtcg
    19861 tatttgtcat gattgcgggc ttttcaggcg tcatcctcgg gcctcttttc ctaaaatggc
    19921 ttcgcatacg cagttccctt ggacaaggca ttgcattagg cagcgcctcc catgcactgg
    19981 gtacctccaa agcgttggaa tatggggaat tggccgtatc catgagttcc gtctccatga
    20041 cgctttgtgc ggtgctcggc tcattcttcg gcccgctcgt cgtctggctg tttcatattt
    20101 aacaaagaaa gactgccccg ggggagggca gtctttttcg tttaagaagc aaaaaaatca
    20161 atcagcggct gaaagtcctt agataaatca acgtcattcg gttctgcttg aagcaggcgg
    20221 tcaatcatac gctccagctc ctcaacatca ttcttatcgg tatattcaat
//
