LOCUS       NZ_NJRE01000007        27659 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain 18-3 18-3_R1_(paired)_contig_7, whole
            genome shotgun sequence.
ACCESSION   NZ_NJRE01000007
VERSION     NZ_NJRE01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 203493)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 203493)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010578165.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:36:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,453
            CDSs (total)                      :: 4,376
            Genes (coding)                    :: 4,252
            CDSs (with protein)               :: 4,252
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 5, 2 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 72 of 124
            Pseudo Genes (incomplete)         :: 64 of 124
            Pseudo Genes (internal stop)      :: 16 of 124
            Pseudo Genes (multiple problems)  :: 23 of 124
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:28:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 27659
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NJRE01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27659
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..27659
                     /SMILES="NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27659
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:7659](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..7659)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            complement(<1..7659)
                     /gene="srfAA"
                     /locus_tag="CE047_RS16000"
     CDS             complement(<1..7659)
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (4-303). E-value:
                     5.1e-98. Score: 320.0. Matches aSDomain:
                     nrpspksdomains_CE047_RS16000_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (466-867). E-value:
                     1.6e-112. Score: 368.1. Matches aSDomain:
                     nrpspksdomains_CE047_RS16000_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (976-1044). E-value: 2.6e-24. Score:
                     77.2. Matches aSDomain: nrpspksdomains_CE047_RS16000_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1058-1345). E-value:
                     8.9e-106. Score: 345.2. Matches aSDomain:
                     nrpspksdomains_CE047_RS16000_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1510-1908). E-value:
                     1.8e-109. Score: 358.0. Matches aSDomain:
                     nrpspksdomains_CE047_RS16000_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2015-2084). E-value: 3.6e-30.
                     Score: 96.0. Matches aSDomain:
                     nrpspksdomains_CE047_RS16000_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2098-2384). E-value:
                     4.8e-109. Score: 355.9. Matches aSDomain:
                     nrpspksdomains_CE047_RS16000_Condensation_LCL.2"
                     /codon_start=1
                     /gene="srfAA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388230.2"
                     /locus_tag="CE047_RS16000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="surfactin non-ribosomal peptide synthetase SrfAA"
                     /protein_id="WP_163136463.1"
                     /sec_met_domain="PP-binding (E-value: 4.8e-15, bitscore:
                     49.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-121, bitscore:
                     398.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.6e-98, bitscore:
                     323.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITFYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDYV
                     LVEQAIQEFIRRNDAIRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQWS
                     REETKKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYLELA
                     SGSETKEGISHSFIDHVLSEQEYAQSKRFEKDKAFWNKQFESVPELVSLKRNASAGGSL
                     DAERFSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTFMGNRT
                     NAKEKQMLGMFVSTVPLRTNIDGGQAFSEFVKDRMKDLMKTLRHQKYPYNLLINDLRET
                     KSSLTKLFTVSLEYQVMQWQKEEDLAFLTEPIFSGSGLNDVSIHVKDRWDTGKLTIDFD
                     YRTDLFSREEINMICERMITMLENALTHPEHTIDELTMISDAEKEKLLARAGGESVSYR
                     KDMTIPELFQEKAEQLSDHPAVVFEGRTLSYRTLHEQSARIANVLKQKGVGPDSPVAVL
                     IERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTESKVAAPEADAE
                     LIDLDQAIAEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVESLQQTI
                     YQSGSQTLRMALLAPFHFDASVKQIFASLLLGQTLYIVPKKTVTNGAALTAYYRKNSIE
                     ATDGTPAHLQMLAAAGDFEGLKLKHMLIGGEGLSSVVADKLLKLFKEAGTAPRLTNVYG
                     PTETCVDASVHPVIPESAVQSAYVPIGKALGNNRLYILDQKGRLQPEGVAGELYIAGDG
                     VGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEYLGREDDQVKVRGYRI
                     ELGEIEAVIQQAPDVAKAVVLARPDEQGNLEVCAYVVQKPGSEFAPAGLREHAARQLPD
                     YMVPAYFTEVTEIPLTPSGKVDRRKLFALEVKAVSGTAYTAPRNETEKAIAAIWQDVLN
                     VEKAGIFDNFFETGGHSLKAMTLLTKIHKETGIEIPLQFLFEHPTIAALAEEADHRESK
                     AFAVIEPAEKQEHYPLSLAQQRTYIVSQFEDAGVGYNMPAAAILEGPLDIQKLERAFQG
                     LIRRHESLRTSFVLENSTPRQNIHDSVDFNIEMIERGGRSDEAIMASFVRTFDLAKAPL
                     FRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELARIYKGEQLPELRLQYKDYAVWQ
                     SRQAAEGYKKDQVYWKEVFAGEIPVLQLLSDYPRPPVQSFEGDRVSIKLDAGVKDRLNR
                     LAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPSAGRNHSDTEGIIGMFVNTLALRS
                     EVKQDETFTQLISRVRKRVLNAFSHQDYPFEWLVEELNIPRDVSRHPLFDTMFSLQNAT
                     EGIPAVGDLSLSVHETNFKIAKFDLTVQARETDEGIELDLDYSTKLFKQSTADRLLTHF
                     ARLLEDAAADPEKPISEYKLLSEEEAASQIQQFNPGRTPYPKDKTIVQLFEEQAANTPD
                     HTALQYEGESLTYRELNERANRLARGILSLGAGEGRTAAVLCERSMDMIVSILAVLKSG
                     SAYVPIDPEHPIQRMQHFFRDSGAKVLLTQRKLKALAEEAEFKGVIVLADEEESYHADA
                     RNLALPLDSAAMANLTYTSGTTGTPKGNIVTHANILRTVKETNYLSITEQDTILGLSNY
                     VFDAFMFDMFGSLLNGAKLVLIPKETVLDMARLSRVIERENISILMITTALFHLLVDLN
                     PACLSTLRKIMFGGERASVEHVRKALQTVGKGKLLHMYGPSESTVFATYHPVDELEEHT
                     LSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVSGEGLVKGYYNRPELTEEKFVPHPF
                     TSGERMYKTGDLARWLPNGDIEFIGRIDHQVKIRGQRIELGEIEHQLQTHDRVQESVVL
                     AVDQGAGDKLLCAYYVGEGDISSQEMREHAAKDLPAYMVPAVFIQMDELPLTGNGKIDR
                     RALPIPDANVSRGVSYVAPRNGTEQKVADIWAQVLQAEQVGVYDHFFDIGGHSLAGMKM
                     LALVHQELGVELSLKDLFQSPTVEGLAQVIASAEKGTAASISPAEKQDTYPVSSPQKRM
                     YVLQQLEDAQTSYNMPAVLRLTGELDVERLNSVMQQLMQRHEALRTTFEIKDGETVQRI
                     WEEAECEIAYFEAPEEETERIVSEFIKPFKIDQLPLFRIGLIKHSDTEHVLLFDMHHII
                     SDGASVGVLIEELSKLYDGETLEPLRIQYKDYAVWQQQFIQSELYKKQEEHWLKELDGE
                     LPVLTLPTDYSRPAVQTFEGDRIAFSLEAGKADALRRLAKETDSTLYMVLLASYSAFLS
                     KLSGQDDIIVGSPVAGRSQADVSRVIGMFVNTLALRTYPKGEKTFADYLNEVKETALSA
                     FDAQDYPLEDLIGNVQVQRDTSRNPLFDAVFSMQNANIKDLTMKGIQLEPHPFERKTAK
                     FDLTLTVDETDGGLTFVLEYNTALFKQETIERWKQYWMELLDAVTGNPNQPLSSLSLVT
                     ETEKQALLEAWKGKALPVPTDKTVHQLFEE"
     CDS_motif       complement(346..465)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0025"
                     /evalue="2.10E-12"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2438"
                     /protein_start="2398"
                     /score="39.3"
                     /tool="antismash"
                     /translation="KETALSAFDAQDYPLEDLIGNVQVQRDTSRNPLFDAVFSM"
     aSDomain        complement(508..1365)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.80E-109"
                     /label="CE047_RS16000_Condensation_LCL.2"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2384"
                     /protein_start="2098"
                     /score="355.9"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="DTYPVSSPQKRMYVLQQLEDAQTSYNMPAVLRLTGELDVERLNSV
                     MQQLMQRHEALRTTFEIKDGETVQRIWEEAECEIAYFEAPEEETERIVSEFIKPFKIDQ
                     LPLFRIGLIKHSDTEHVLLFDMHHIISDGASVGVLIEELSKLYDGETLEPLRIQYKDYA
                     VWQQQFIQSELYKKQEEHWLKELDGELPVLTLPTDYSRPAVQTFEGDRIAFSLEAGKAD
                     ALRRLAKETDSTLYMVLLASYSAFLSKLSGQDDIIVGSPVAGRSQADVSRVIGMFVNTL
                     ALRTY"
     CDS_motif       complement(514..603)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0024"
                     /evalue="3.70E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2382"
                     /protein_start="2352"
                     /score="45.0"
                     /tool="antismash"
                     /translation="DIIVGSPVAGRSQADVSRVIGMFVNTLALR"
     CDS_motif       complement(862..894)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0023"
                     /evalue="2.90E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2266"
                     /protein_start="2255"
                     /score="13.5"
                     /tool="antismash"
                     /translation="QYKDYAVWQQQ"
     CDS_motif       complement(925..990)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0022"
                     /evalue="6.60E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2245"
                     /protein_start="2223"
                     /score="31.5"
                     /tool="antismash"
                     /translation="MHHIISDGASVGVLIEELSKLY"
     CDS_motif       complement(1186..1299)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0021"
                     /evalue="3.30E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2158"
                     /protein_start="2120"
                     /score="58.1"
                     /tool="antismash"
                     /translation="TSYNMPAVLRLTGELDVERLNSVMQQLMQRHEALRTTF"
     aSDomain        complement(1408..1614)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_PCP.2"
                     /evalue="3.60E-30"
                     /label="CE047_RS16000_PCP.2"
                     /locus_tag="CE047_RS16000"
                     /protein_end="2084"
                     /protein_start="2015"
                     /score="96.0"
                     /tool="antismash"
                     /translation="EQKVADIWAQVLQAEQVGVYDHFFDIGGHSLAGMKMLALVHQELG
                     VELSLKDLFQSPTVEGLAQVIASA"
     aSModule        complement(1408..4485)
                     /complete
                     /domains="nrpspksdomains_CE047_RS16000_Condensation_LCL.1"
                     /domains="nrpspksdomains_CE047_RS16000_AMP-binding.2"
                     /domains="nrpspksdomains_CE047_RS16000_PCP.2"
                     /locus_tags="CE047_RS16000"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1906..1971)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0020"
                     /evalue="3.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1918"
                     /protein_start="1896"
                     /score="38.0"
                     /tool="antismash"
                     /translation="FIGRIDHQVKIRGQRIELGEIE"
     aSDomain        complement(1936..3129)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_AMP-binding.2"
                     /evalue="1.80E-109"
                     /label="CE047_RS16000_AMP-binding.2"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1908"
                     /protein_start="1510"
                     /score="358.0"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEEQAANTPDHTALQYEGESLTYRELNERANRLARGILSLGAGEG
                     RTAAVLCERSMDMIVSILAVLKSGSAYVPIDPEHPIQRMQHFFRDSGAKVLLTQRKLKA
                     LAEEAEFKGVIVLADEEESYHADARNLALPLDSAAMANLTYTSGTTGTPKGNIVTHANI
                     LRTVKETNYLSITEQDTILGLSNYVFDAFMFDMFGSLLNGAKLVLIPKETVLDMARLSR
                     VIERENISILMITTALFHLLVDLNPACLSTLRKIMFGGERASVEHVRKALQTVGKGKLL
                     HMYGPSESTVFATYHPVDELEEHTLSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVS
                     GEGLVKGYYNRPELTEEKFVPHPFTSGERMYKTGDLARWLPNGDIEFIGRIDHQVKIR"
     CDS_motif       complement(2053..2142)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0019"
                     /evalue="2.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1869"
                     /protein_start="1839"
                     /score="42.4"
                     /tool="antismash"
                     /translation="PAGIAGELCVSGEGLVKGYYNRPELTEEKF"
     CDS_motif       complement(2257..2280)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0018"
                     /evalue="8.00E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1801"
                     /protein_start="1793"
                     /score="3.4"
                     /tool="antismash"
                     /translation="YGPSESTV"
     CDS_motif       complement(2650..2703)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0017"
                     /evalue="6.40E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1670"
                     /protein_start="1652"
                     /score="18.8"
                     /tool="antismash"
                     /translation="LTYTSGTTGTPKGNIVTH"
     CDS_motif       complement(2902..2943)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0016"
                     /evalue="2.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1586"
                     /protein_start="1572"
                     /score="14.6"
                     /tool="antismash"
                     /translation="LAVLKSGSAYVPID"
     CDS_motif       complement(3466..3585)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0015"
                     /evalue="2.50E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1398"
                     /protein_start="1358"
                     /score="64.9"
                     /tool="antismash"
                     /translation="RKRVLNAFSHQDYPFEWLVEELNIPRDVSRHPLFDTMFSL"
     aSDomain        complement(3625..4485)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.90E-106"
                     /label="CE047_RS16000_Condensation_LCL.1"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1345"
                     /protein_start="1058"
                     /score="345.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLISDG"
                     /tool="antismash"
                     /translation="QEHYPLSLAQQRTYIVSQFEDAGVGYNMPAAAILEGPLDIQKLER
                     AFQGLIRRHESLRTSFVLENSTPRQNIHDSVDFNIEMIERGGRSDEAIMASFVRTFDLA
                     KAPLFRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELARIYKGEQLPELRLQYKDY
                     AVWQSRQAAEGYKKDQVYWKEVFAGEIPVLQLLSDYPRPPVQSFEGDRVSIKLDAGVKD
                     RLNRLAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPSAGRNHSDTEGIIGMFVNTL
                     ALRSEV"
     CDS_motif       complement(3634..3723)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0014"
                     /evalue="9.80E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1342"
                     /protein_start="1312"
                     /score="50.1"
                     /tool="antismash"
                     /translation="DIIVGTPSAGRNHSDTEGIIGMFVNTLALR"
     CDS_motif       complement(3979..4011)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0013"
                     /evalue="6.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1227"
                     /protein_start="1216"
                     /score="12.5"
                     /tool="antismash"
                     /translation="QYKDYAVWQSR"
     CDS_motif       complement(4042..4107)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0012"
                     /evalue="1.60E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1206"
                     /protein_start="1184"
                     /score="27.0"
                     /tool="antismash"
                     /translation="MHHLISDGVSIGIMLEELARIY"
     CDS_motif       complement(4300..4410)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0011"
                     /evalue="4.20E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1120"
                     /protein_start="1083"
                     /score="54.5"
                     /tool="antismash"
                     /translation="YNMPAAAILEGPLDIQKLERAFQGLIRRHESLRTSFV"
     aSDomain        complement(4528..4731)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_PCP.1"
                     /evalue="2.60E-24"
                     /label="CE047_RS16000_PCP.1"
                     /locus_tag="CE047_RS16000"
                     /protein_end="1044"
                     /protein_start="976"
                     /score="77.2"
                     /tool="antismash"
                     /translation="EKAIAAIWQDVLNVEKAGIFDNFFETGGHSLKAMTLLTKIHKETG
                     IEIPLQFLFEHPTIAALAEEADH"
     aSModule        complement(4528..7647)
                     /complete
                     /domains="nrpspksdomains_CE047_RS16000_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_CE047_RS16000_AMP-binding.1"
                     /domains="nrpspksdomains_CE047_RS16000_PCP.1"
                     /locus_tags="CE047_RS16000"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5029..5094)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0010"
                     /evalue="3.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="CE047_RS16000"
                     /protein_end="877"
                     /protein_start="855"
                     /score="38.1"
                     /tool="antismash"
                     /translation="YLGREDDQVKVRGYRIELGEIE"
     aSDomain        complement(5059..6261)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_AMP-binding.1"
                     /evalue="1.60E-112"
                     /label="CE047_RS16000_AMP-binding.1"
                     /locus_tag="CE047_RS16000"
                     /protein_end="867"
                     /protein_start="466"
                     /score="368.1"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FQEKAEQLSDHPAVVFEGRTLSYRTLHEQSARIANVLKQKGVGPD
                     SPVAVLIERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTESKVAA
                     PEADAELIDLDQAIAEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVE
                     SLQQTIYQSGSQTLRMALLAPFHFDASVKQIFASLLLGQTLYIVPKKTVTNGAALTAYY
                     RKNSIEATDGTPAHLQMLAAAGDFEGLKLKHMLIGGEGLSSVVADKLLKLFKEAGTAPR
                     LTNVYGPTETCVDASVHPVIPESAVQSAYVPIGKALGNNRLYILDQKGRLQPEGVAGEL
                     YIAGDGVGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEYLGREDDQVK
                     VR"
     CDS_motif       complement(5176..5265)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0009"
                     /evalue="5.00E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="CE047_RS16000"
                     /protein_end="828"
                     /protein_start="798"
                     /score="47.6"
                     /tool="antismash"
                     /translation="PEGVAGELYIAGDGVGRGYLHLPELTEEKF"
     CDS_motif       complement(5383..5406)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0008"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="CE047_RS16000"
                     /protein_end="759"
                     /protein_start="751"
                     /score="5.7"
                     /tool="antismash"
                     /translation="YGPTETCV"
     CDS_motif       complement(5797..5856)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0007"
                     /evalue="7.40E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="CE047_RS16000"
                     /protein_end="621"
                     /protein_start="601"
                     /score="33.8"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGRPKGVMIEH"
     CDS_motif       complement(6034..6075)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0006"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="CE047_RS16000"
                     /protein_end="542"
                     /protein_start="528"
                     /score="17.8"
                     /tool="antismash"
                     /translation="MGILKAGGAYVPID"
     CDS_motif       complement(6598..6711)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0005"
                     /evalue="6.50E-10"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="CE047_RS16000"
                     /protein_end="354"
                     /protein_start="316"
                     /score="31.6"
                     /tool="antismash"
                     /translation="KDLMKTLRHQKYPYNLLINDLRETKSSLTKLFTVSLEY"
     aSDomain        complement(6751..7647)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE047_RS16000_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="5.10E-98"
                     /label="CE047_RS16000_Condensation_Starter.1"
                     /locus_tag="CE047_RS16000"
                     /protein_end="303"
                     /protein_start="4"
                     /score="320.0"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVISDG"
                     /tool="antismash"
                     /translation="FYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDYVLVEQ
                     AIQEFIRRNDAIRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQWSREET
                     KKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYLELASGSE
                     TKEGISHSFIDHVLSEQEYAQSKRFEKDKAFWNKQFESVPELVSLKRNASAGGSLDAER
                     FSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTFMGNRTNAKE
                     KQMLGMFVSTVPLRTNID"
     CDS_motif       complement(6763..6852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0004"
                     /evalue="9.30E-12"
                     /label="C5_starter_265-294"
                     /locus_tag="CE047_RS16000"
                     /protein_end="299"
                     /protein_start="269"
                     /score="37.3"
                     /tool="antismash"
                     /translation="DVVTGTFMGNRTNAKEKQMLGMFVSTVPLR"
     CDS_motif       complement(7183..7248)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0003"
                     /evalue="1.70E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="CE047_RS16000"
                     /protein_end="159"
                     /protein_start="137"
                     /score="20.7"
                     /tool="antismash"
                     /translation="VHHVISDGISMNILGNAIMHIY"
     CDS_motif       complement(7462..7581)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0002"
                     /evalue="4.00E-06"
                     /label="C2_starter_024-063"
                     /locus_tag="CE047_RS16000"
                     /protein_end="66"
                     /protein_start="26"
                     /score="19.5"
                     /tool="antismash"
                     /translation="ISNLAGIGKLVSADAIDYVLVEQAIQEFIRRNDAIRLRLR"
     CDS_motif       complement(7606..7644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE047_RS16000_0001"
                     /evalue="6.60E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="CE047_RS16000"
                     /protein_end="18"
                     /protein_start="5"
                     /score="9.5"
                     /tool="antismash"
                     /translation="YPLTDAQKRIWYT"
     misc_feature    complement(8085..8099)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.42"
                     /tool="antismash"
     misc_feature    8104..8117
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.77"
                     /tool="antismash"
     gene            complement(8233..8595)
                     /gene="hxlR"
                     /locus_tag="CE047_RS16005"
     CDS             complement(8233..8595)
                     /codon_start=1
                     /gene="hxlR"
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388229.2"
                     /locus_tag="CE047_RS16005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional activator HxlR"
                     /protein_id="WP_003246265.1"
                     /transl_table=11
                     /translation="MSRMDDKRFNCEKELTLAVIGGKWKMLILWHLGKEGTKRFNELKT
                     LIPDITQKILVNQLRELEQDMIVHREVYPVVPPKVEYSLTPHGESLMPILEAMYEWGKG
                     YMELIDIDKNVMKESL"
     gene            8827..9459
                     /gene="hxlA"
                     /locus_tag="CE047_RS16010"
     CDS             8827..9459
                     /EC_number="4.1.2.43"
                     /GO_function="GO:0043801 - hexulose-6-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019647 - formaldehyde assimilation via
                     ribulose monophosphate cycle [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388228.1"
                     /locus_tag="CE047_RS16010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="WP_021481819.1"
                     /transl_table=11
                     /translation="MELQLALDLVNIPEAIELVKEVEQYIDVVEIGTPVVINEGLRAVK
                     EIKEAFPQLKVLADLKIMDAGGYEIMKASEAGADIITVLGATDDATIKGAVEEAKKQKK
                     KILVDMINVKDIESRAQEIDALGVDYICVHTGYDLQAEGKNSFEELTTIKNTVKNAKTA
                     IAGGIKLDTLPEVIQQKPDLVIVGGGITSAADKAETASKMKQLIAQG"
     gene            9465..10022
                     /gene="hxlB"
                     /locus_tag="CE047_RS16015"
     CDS             9465..10022
                     /EC_number="5.3.1.27"
                     /GO_function="GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="hxlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388227.1"
                     /locus_tag="CE047_RS16015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="WP_021481820.1"
                     /transl_table=11
                     /translation="MKTTEYVAEILNELHRSAAYISNEEADQLADHILSSHQIFTAGAG
                     RSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAKSL
                     HGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYDAVI
                     LKLMEKKALDSETMFTHHANLE"
     misc_feature    10057..10066
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    complement(10058..10071)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.99"
                     /tool="antismash"
     misc_feature    complement(10059..10072)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.47"
                     /tool="antismash"
     misc_feature    10060..10073
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.86"
                     /tool="antismash"
     misc_feature    10061..10074
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.14"
                     /tool="antismash"
     gene            10133..11854
                     /gene="tlpC"
                     /locus_tag="CE047_RS16020"
     CDS             10133..11854
                     /GO_function="GO:0004888 - transmembrane signaling receptor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="tlpC"
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388226.2"
                     /locus_tag="CE047_RS16020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyl-accepting chemotaxis protein TlpC"
                     /protein_id="WP_161621339.1"
                     /transl_table=11
                     /translation="MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMA
                     TEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQTQINGNEDIVDLLGEKTGDTITIFQ
                     GDTRVATNVMKNGERAVDTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKDQNG
                     NIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIIVSVILVLVFTRKINKRLNALKSAF
                     ESAGNGDMTIEVSDKTGDELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGA
                     EETNQASEKITEAVQQIANGAQDQITRIENSESSLKQASADIRDISANTAAIADKGQLA
                     QSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLL
                     ALNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEH
                     VKTEAAEGVTMIQRTRDAFKEIAAATGEISAEISDLSASVTNISASAHHINDSFAANTA
                     DIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGIISQFKMINQAANG"
     misc_feature    11863..11876
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.98"
                     /tool="antismash"
     gene            12022..12471
                     /gene="nucA"
                     /locus_tag="CE047_RS16025"
     CDS             12022..12471
                     /EC_number="3.-.-.-"
                     /codon_start=1
                     /gene="nucA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388225.3"
                     /locus_tag="CE047_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-entry nuclease"
                     /protein_id="WP_014475770.1"
                     /transl_table=11
                     /translation="MNITTDIIKTILLVIVIIAAAAVGLIKGDFFSADQKTSQTKEYDE
                     TIAFPSDRYPETAKHIKDAINEGHSEVCTIDRDGAEERREQSLKDVPSKKGYDRDEWPM
                     AMCKEGGEGASVEYISPADNRGAGSWVGHQLTDYPDGTKVLFTIQ"
     gene            12498..12896
                     /gene="nin"
                     /locus_tag="CE047_RS16030"
     CDS             12498..12896
                     /codon_start=1
                     /gene="nin"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388224.1"
                     /locus_tag="CE047_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA-entry nuclease inhibitor"
                     /protein_id="WP_021481824.1"
                     /transl_table=11
                     /translation="MIKSWKPQELSISYHQFTVFQKDSTPPVMDWTDEAIEKGYAAADG
                     AISFEAQRNTKAFILLRLNSSETVNSYEKKVTVPFHVTENGIHIESIMSKRLSFDLPKG
                     DYQLTCWTVPAEMSDLHADTYIIDAVSV"
     gene            complement(12933..14366)
                     /gene="bglC"
                     /locus_tag="CE047_RS16035"
     CDS             complement(12933..14366)
                     /EC_number="3.2.1.86"
                     /codon_start=1
                     /gene="bglC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388223.1"
                     /locus_tag="CE047_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="WP_046160040.1"
                     /transl_table=11
                     /translation="MIHQHPESFPKHFLWGSASAAYQIEGAWNEDGKGPSVWDVFTKIP
                     GKTFKGTNGDIAVDHYHRFKEDVALMAEMGLKAYRFSVSWPRIFPKGKGEINEAGLAFY
                     DRLIDELLSHHIEPVLTLYHWDLPQALMDEYGGFESRNIIEDFNHYCITLYKRFGDRVK
                     YWVTLNEQNYNFNHGFITAMHPPGVKDRKRFYEANHIAFLANAKAIESFREYVPEGKIG
                     PSFAYSPAYPLSSHPEDILAFENAEEFTNNWWLDMYCWGTYPQIPFRYLEKQGWAPTIE
                     PGDMDLLAKGKPDFVGVNYYQTITYERNPLDGVSEGKMNTTGQKGTNQETGIPGVFKTK
                     KNPHLTTSNWDWTIDPIGLRIGLRRITSRYQLPVFITENGLGEFDKVEDGTVQDDYRID
                     YLRSHLEQCRQAISDGVDLIGYCSWSFTDLLSWLNGYQKRYGFVYVNRDEESTSDLKRL
                     KKKSFYWYQDVIKTNGESL"
     misc_feature    14394..14414
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.59"
                     /tool="antismash"
     gene            complement(14438..15166)
                     /locus_tag="CE047_RS16040"
     CDS             complement(14438..15166)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014662733.1"
                     /locus_tag="CE047_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AAA family ATPase"
                     /protein_id="WP_021481826.1"
                     /transl_table=11
                     /translation="MFLKKVTLLRDKILDFDRFPFTIPAISQLNDILFTSQVTFFVGEN
                     GSGKSTLLEAIADKCEFNTAGGSRNNVYELRESDSHLGDYIRLSWLPKVTNGFFLRAES
                     FYHLSLHLDEMELDAPQPYRSYGGRPLHNQSHGESFMSLFRHRFKEKAIYLLDEPEAAL
                     SPARQLAFLRVIHDLVKGGNVQMIIATHSPILLGYPNANILSFDGGRIHHIEYENTEHV
                     QLTRYFLGQREKILAELFRD"
     gene            complement(15185..15526)
                     /locus_tag="CE047_RS16045"
     CDS             complement(15185..15526)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003224880.1"
                     /locus_tag="CE047_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3147 family protein"
                     /protein_id="WP_032724911.1"
                     /transl_table=11
                     /translation="MAVLSKVIISALIIGFVTEISKRHPTYGGIIAALPLVSLLSLFWM
                     QIQGEKTAQLSQFASGVLTGIPATVCLLAILAFLLKIHVPFWFALCVGILGWAMFLWMQ
                     KIFLNILFN"
     gene            complement(15514..15936)
                     /locus_tag="CE047_RS16050"
     CDS             complement(15514..15936)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014478795.1"
                     /locus_tag="CE047_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_170939093.1"
                     /transl_table=11
                     /translation="MEMDLISKLNQQWTDIYYLLHYQHKDNISHQAIRIMQHIEKQGEA
                     TIGALAEYLSVSHNTASEHTKRLIQKGFIAKRRSQQDERKVLVFLTQEGRSVLEQHTQL
                     DKEKLKEIIERMSTSEKKLLEQAFELLSREAKQWQF"
     misc_feature    15991..16005
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.42"
                     /tool="antismash"
     gene            complement(16063..16395)
                     /gene="yckD"
                     /locus_tag="CE047_RS16055"
     CDS             complement(16063..16395)
                     /codon_start=1
                     /gene="yckD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388222.1"
                     /locus_tag="CE047_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YckD family protein"
                     /protein_id="WP_021481829.1"
                     /transl_table=11
                     /translation="MKRITINIITMFIAAAVISLTGTAEAAEKQQQPPANVTLTDQQKK
                     EIEQLEAEILKKRKDVISKYVQYGVLPKERGEHIKNHLDKHFEMMKQNGFVPKHHPHPH
                     KFEKRH"
     gene            complement(16476..16932)
                     /gene="yckC"
                     /locus_tag="CE047_RS16060"
                     /pseudo=""
     CDS             complement(16476..16932)
                     /codon_start=1
                     /gene="yckC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388221.1"
                     /locus_tag="CE047_RS16060"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="RDD family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNIYKPAGYWIRLGAALLDYIIVSVPLLLIYWLITGKDPNDSMFI
                     SLVVLLYSILLPVFWRGYLIGKRICGIRIVKKRRITSQLVNNVFTGYCSRPGLRYNLRT
                     RLDRQPDSNCRTRRQTDPA"
     gene            complement(16951..17147)
                     /locus_tag="CE047_RS16065"
                     /pseudo=""
     CDS             complement(16951..17147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009513942.1"
                     /locus_tag="CE047_RS16065"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSKDECQTYQGNTCESEGCSRPVTHLCQYRKKWSRDMKPIIRII"
     gene            17309..18172
                     /gene="yckB"
                     /locus_tag="CE047_RS16070"
     CDS             17309..18172
                     /codon_start=1
                     /gene="yckB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388220.1"
                     /locus_tag="CE047_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_080481234.1"
                     /transl_table=11
                     /translation="MKSFMHSKAVIFSFTMAFFLILAACSGKNEADSKDTGWEQIKDKG
                     KIVVATSGTLYPTSYHDTDSGSDKLTGYEVEVVREAAKRLGLKVEFKEMGIDGMLTAVN
                     SGQVDAAANDIDVTKDREKKFAFSTPYKYSYGTAIVRKDDLSGIKTLKDLKGKKAAGAA
                     TTVYMEVARKYGAKEVIYDNATNEQYLKDVANGRTDVILNDYYLQTLALAAFPDLNITI
                     HPDIKYMPNKQALVMKKSNAALQKKMNEALKEMGKDGSLTKLSKQFFNKADVSKKIDAD
                     VQDVDL"
     gene            18182..18862
                     /gene="yckA"
                     /locus_tag="CE047_RS16075"
     CDS             18182..18862
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yckA"
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388219.1"
                     /locus_tag="CE047_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_003234624.1"
                     /transl_table=11
                     /translation="MINSIQWEYIFNTKLAIESFPYVIKGIGYTLLISFVSMFAGTVIG
                     LFISLARMSKLALLRWPAKLYISFMRGVPILVILFILYFGFPYIGIEFSAVTAALIGFS
                     LNSAAYIAEINRSAISSVEKGQWEAASSLGLSYWQTMRGIILPQSIRIALPPLANVLLD
                     LIKASSLAAMITVPELLQHAKIIGGREFDYMTMYILTALIYWAICSIAAVFQNILEKKY
                     AHYV"
     gene            complement(18910..20103)
                     /gene="zinU"
                     /gene_synonym="yciC"
                     /locus_tag="CE047_RS16080"
     CDS             complement(18910..20103)
                     /codon_start=1
                     /gene="zinU"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178: cobalamin synthesis protein/P47K family protein"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="yciC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388218.1"
                     /locus_tag="CE047_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc metallochaperone ZinU"
                     /protein_id="WP_021481831.1"
                     /transl_table=11
                     /translation="MKKIPVTVLSGYLGAGKTTLLNSILQNREGLKIAVIVNDMSEVNI
                     DAGLVKQEGGLSRTDEKLVEMSNGCICCTLREDLLIEVEKLAKDGRFDYIVIESTGISE
                     PIPVAQTFSYIDEEMGIDLTKFCQLDTMVTVVDANRFWHDYQSGESLLDRKEALGEEDE
                     REIADLLIDQIEFCDVLILNKCDLVSEQELEQLENVLRKLQPRARFIRSVKGNVKPQEI
                     LHTGLFNFEEASGSAGWIQELTAGHAEHIPETEEYGISSFVYKRRLPFHSTRFYRWLDQ
                     MPKNVVRAKGIVWCASHNNLALLMSQAGPSVTIEPVSYWVAALPKLEQEQVKQQEPEIL
                     EEWDPEFGDRLTQLVFIGTDLDEETITKELDQCLLTEYEFDSDWSLFEDPFKWKLNQ"
     gene            complement(20131..20289)
                     /locus_tag="CE047_RS16085"
                     /pseudo=""
     CDS             complement(20131..20289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097674.1"
                     /locus_tag="CE047_RS16085"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKDLAVGKDLRWGKRIKRGWSLY"
     gene            complement(20407..20991)
                     /gene="yciB"
                     /locus_tag="CE047_RS16090"
     CDS             complement(20407..20991)
                     /EC_number="2.3.2.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /gene="yciB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388217.2"
                     /locus_tag="CE047_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L,D-transpeptidase"
                     /protein_id="WP_163136465.1"
                     /transl_table=11
                     /translation="MKLSLFIIAVLMPASLLSACSDHAEEHASINTKKTVKNITDVRKT
                     AKTSIDWTKSSGGEYPDIKQKHVWIDVNVKEQKAYIKEGSNTIYTMMISSGLDQTKDDA
                     TPKGTFYVEPERGEWFFSEGYQEGAEYWVSWKNHGEFLFHSVPMTKDQKVIKTEAEKLG
                     TKASHGCIRLTIPDAKWVYENIPEHTKVVIS"
     gene            complement(20988..21902)
                     /gene="folE2"
                     /locus_tag="CE047_RS16095"
     CDS             complement(20988..21902)
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="folE2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388216.2"
                     /locus_tag="CE047_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="WP_163136467.1"
                     /transl_table=11
                     /translation="MNQHTLLPKKTERLQYFGSVSPIKGEKPVEKEKMKDLQNIRKDYF
                     FDIQHVGVANVSHPVTITSAMMPAEQTTAANFTMTCNLPRNQKGINMSRLTELLQVYHQ
                     NGWVLSFSSLQQFTKELAENMDISSATVEVRFPWFFERKSPKLEKAGLMHADIFMSVTY
                     RKDQPFKQRAGISAKVTTLCPCSKEISEYSAHNQRGTVSIWADIHPAASLPSDVKADLL
                     HAAESNASARLYPVLKRPDEKAVTETAYENPRFVEDLARLIAADLFELEWVSAFEIECR
                     NEESIHLHDAYAKLCFSKEVDKI"
     gene            complement(22019..23224)
                     /gene="nasA"
                     /locus_tag="CE047_RS16100"
     CDS             complement(22019..23224)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nasA"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388215.2"
                     /locus_tag="CE047_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrate/nitrite transporter"
                     /protein_id="WP_015252853.1"
                     /transl_table=11
                     /translation="MKLSELKTSGHPLTLLCSFLYFDVSFMIWVMLGALGVYISQDFGL
                     SPFEKGLVVAVPILSGSVFRIILGILTDRIGPKKTAVIGMLVTMIPLLWGTFGGRSLTE
                     LYAIGILLGVAGASFAVALPMASRWYPPHLQGLAMGIAGAGNSGTLFATLFGPRLAEQF
                     GWHIVMGIALIPLLIVFILFVSMAKDSPAQPAPQPLKSYLHVFGQKETWFFCLLYSVTF
                     GGFVGLSSFLSIFFVDQYQLSKIHAGDFVTLCVAAGSFFRPVGGLISDRVGGTKVLSVL
                     FVIVALCMAGVSSLPSLSMVIVLLFVGMMGLGMGNGAVFQLVPQRFRKEIGMVTGIVGA
                     AGGIGGFFLPNILGSLKQMTGTYAIGFITFSCIALLAFALVLAAGYYWRKSWSAESSPA
                     DV"
     gene            23404..25719
                     /gene="nasB"
                     /locus_tag="CE047_RS16105"
     CDS             23404..25719
                     /codon_start=1
                     /gene="nasB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388214.2"
                     /locus_tag="CE047_RS16105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="assimilatory nitrate reductase electron transfer
                     subunit NasB"
                     /protein_id="WP_163136469.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.3e-59, bitscore:
                     192.8, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 3.3e-17, bitscore:
                     56.3, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQRLVLAGNGMAGIRCIEEVLKLNHHMFEIVIFGSEPHPNYNR
                     ILLSSVLQGEASLDDITLNSKDWYDKHGITLYTGETVIQIDTDQQQVITDRKRTLSYDK
                     LIVATGSSPHILPIPGADKKGVYGFRTIEDCQALMKMAQHFQKAAVIGAGLLGLEAAVG
                     LQHLGMDVSVIHHSAGIMQKQLDQTAARLLQTELEQKGLTFLLEKDTVSISGATKADRI
                     HFKDGSSLKADLIVMAAGVRPNIELAVSAGIKVNRGIIVNDFMQTSEPNIYAVGECAEH
                     NGTVYGLVAPLYEQGKALASHICGVPCEEYQGSAPSAALKIAGIDVWSAGKIQEDERTT
                     SIKIYDEQAGVYKKALFVDDKLAGVILFGDTRDKQRLLDSLLKQRDISIVKKQIIEPET
                     SGPLLESMPSSETICQCNTVTKGAIEDAVHTNSLTTVEEVKHCTKATGSCGGCKPLVED
                     LLRHMTNSEYTKPAGTPSFCSCTDFTEDDIIAELQRRPFTNPAEVMNQLDWRTKKGCST
                     CVPAIQYYLEMLYPGFVQPEPATEETCILIPQMYGGRTNAEQLRTIANIIEAYSIPDVS
                     ITHGQRLKLSGIKPADLPNIKKDLKMPVYTNEHRHALQSIKACTCGQNRSIQQLAAQIE
                     RQLETLPLPAPISISLSCETDCTDAALQDVGAIRTQAGWDIYIGGVRGTHARSGALFCV
                     TENEDSTAGMIKGLIQYYRETAHYLEAVHQWIDRLGIVHIREVLFEEDLRAQLLESLQT
                     DLSLIQNPTVETGAYKKG"
     misc_feature    complement(25821..25833)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    complement(26372..26385)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(27016..27031)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.09"
                     /tool="antismash"
     misc_feature    complement(27318..27334)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.77"
                     /tool="antismash"
ORIGIN
        1 ctcttcgaat agctgatgaa ctgttttgtc tgtcggcaca ggcagcgcct tgcccttcca
       61 tgcctcaaga agcgcttgct tttctgtctc tgtgaccagt gacaggctgg aaagcggctg
      121 gttcgggttc ccagtaactg catctaaaag ctccatccaa tattgcttcc atcgttcaat
      181 cgtttcctgc ttaaacagag ctgtattgta ttcgagtacg aatgtaagcc ctccgtcggt
      241 ttcgtcaacc gtcagcgtga ggtcaaactt ggctgttttc cgttcaaacg gatgcggctc
      301 aagctgaatc cctttcattg ttaaatcctt tatattcgca ttttgcattg aaaaaactgc
      361 atcgaataac gggtttctgc ttgtgtcacg ctgaacttga acatttccga tcaaatcctc
      421 aagcgggtaa tcctgcgcat caaatgcgct gagtgccgtt tctttcactt cgttaagata
      481 gtcagcaaag gtcttttcac ccttcggata cgtgcgaagc gccaatgtat tgacgaacat
      541 tccgatgacg cggctgacgt ccgcttgaga tcgtccggcc acaggtgaac cgacgatgat
      601 atcgtcttgc ccgctaagtt ttgataaaaa tgcactgtat gaagccagaa gcaccatgta
      661 aagcgtggaa tccgtttctt ttgcaagcct gcgcagagca tcagctttgc ctgcttctaa
      721 tgaaaatgca atgcggtctc cctcaaatgt ttgaacggca ggccgactgt aatcagtcgg
      781 aagcgtcagc accggcagct ctccgtccag ctccttcagc caatgctctt cttgcttctt
      841 gtaaagctca gactgaatga actgctgctg ccacacggca taatccttat attgaatacg
      901 gagcggctca agggtttctc cgtcgtacag ctttgaaagc tcctcaatca gcacaccgac
      961 agatgcacca tcagaaataa tatgatgcat atcgaacagc agcacatgct cagtgtctga
     1021 atgcttgata agccctattc tgaacagtgg aagttggtcg attttgaaag gcttaataaa
     1081 ctcagaaacg atccgctctg tctcttcttc cggggcttcg aaataggcta tctcgcactc
     1141 agcctcttcc cagatccgct gcaccgtttc tccatctttt atttcaaacg tggttctcaa
     1201 ggcttcatga cgctgcatta actgctgcat gacgctgtta agcctttcaa catcaagctc
     1261 acctgtcagg cgcagaaccg ccggcatgtt atagctcgtt tgcgcatcct caagctgctg
     1321 aagcacgtac atccgttttt gcggtgaaga aacaggatac gtatcttgtt tctctgccgg
     1381 gctgatactt gcggctgtcc ctttttcagc agaggcaatc acctgtgcca agccctcaac
     1441 cgtcggtgat tggaagagat ccttgagtga cagctcaacg cccagttcct gatgaaccaa
     1501 ggcaagcatc ttcatgcctg ctaatgaatg tccgccaatg tcaaagaagt ggtcataaac
     1561 gccgacttgt tctgcctgaa gtacctgtgc ccaaatgtct gcgacttttt gttccgttcc
     1621 attgcgtggc gcaacatatg aaacacctct tgaaacgttg gcatcaggaa tcggcagcgc
     1681 tctccggtca atttttccgt tccctgtcag cggcagctcg tccatttgga taaataccgc
     1741 aggaaccata tatgccggca agtccttcgc agcatgctct ctcatctctt gtgatgagat
     1801 gtctccctct ccgacatagt aagcacacaa cagtttatct cccgctcctt gatcaacggc
     1861 aagcacaaca ctctcctgaa cacgatcatg ggtttgcagc tgatgttcga tttctccaag
     1921 ctcgatgcgc tgtccgcgaa tcttcacctg atggtcgatt cgcccgataa attcgatgtc
     1981 gccattcggc agccatctcg caaggtctcc cgttttatac atgcgttcgc cggatgtaaa
     2041 cggatgggga acaaatttct cctcagtcag ttctggacgg ttgtaatagc ctttcacgag
     2101 tccttcgccg ctgacgcaaa gctctccggc aatcccggca ggctgcacgt gtcccgtacg
     2161 gtcaagaatg tatacttccg tattgctgac cggttttcca atcggaacag acagcgtgtg
     2221 ctcctccaat tcatcaaccg gatgatacgt cgcgaaaacc gtgctttcag acggtccata
     2281 catgtgaagg agcttgccct ttccaaccgt ttgcaaagct tttctgacat gctcaaccga
     2341 ggcccgttcc ccgccaaaca taatcttgcg aagcgttgac aagcatgccg gattcaagtc
     2401 cacaagcaag tggaacaaag cggttgtaat catgagaatg ctgatgttct cccgttcaat
     2461 gacgcgggac aggcgagcca tgtccaaaac ggtttccttc ggtatcagca ccagcttggc
     2521 tccgtttaac aaagagccga acatatcgaa cataaacgcg tcaaacacgt aattggaaag
     2581 accgagaatc gtatcctgtt ctgtaatgct gagataattc gtttccttca ccgtgcggag
     2641 gatattggca tgtgtcacga tattcccctt aggtgttcca gtcgttccgg aagtatacgt
     2701 caggttggcc attgctgcag aatcaagagg cagtgcgaga tttcgcgcat cggcatgata
     2761 gctttcttcc tcatcggcta gcacgataac gcccttaaat tccgcttctt ccgccaaagc
     2821 ctttaatttc ctctgagtga gaagcacctt tgctccgctg tcacggaaga aatgctgcat
     2881 ccgctgaatc ggatgttccg gatcgatcgg aacataagcc gaacctgatt ttaatactgc
     2941 caagatcgac acaatcatat ccattgaccg ctcgcataag acagccgcag ttctgccttc
     3001 gccagctcca agagaaagaa tgccgcgggc taaacgattg gcccgttcat tcagttcacg
     3061 ataagtgagt gattcgcctt catattgaag cgcagtgtgg tctggcgtat tcgccgcttg
     3121 ctcctcaaac agctgaacaa ttgttttatc tttcggataa ggtgttctgc ccgggttaaa
     3181 ctgctgaatt tgcgaagcgg cctcctcttc agaaagaagc ttatactcag aaatcggctt
     3241 ctctggatca gccgcagcat cttcaagcaa acgcgcaaaa tgcgtaagca gcctgtctgc
     3301 cgtgctttgt ttaaacagct tcgtgctgta atccaaatca agctcaatgc cttcatcggt
     3361 ttctctcgcc tgcaccgtca aatcaaattt ggcaatcttg aaattggtct catgaacaga
     3421 caaggacaga tcgccgacag ccggaatgcc ctctgtcgcg ttttgaaggc tgaacatcgt
     3481 gtcaaacagc ggatgcctgc taacatcacg cgggatgttc aattcttcaa caagccactc
     3541 aaacggatag tcctgatgag aaaaggcatt cagcacccgt ttgcggacac gcgagatcaa
     3601 ttgggtaaac gtctcatcct gcttcacctc actgcgaagc gcaagcgtat tgacgaacat
     3661 cccgataatg ccctctgtat cggagtgatt tctgcccgct gacggcgtcc cgacaatgat
     3721 gtcatcctgt cccgtatact ttgacaaaag cgtatagtaa gcggaaagca tcaccatata
     3781 caaagtggcg ccgttttgtt cagccaaacg attgaggcga tcctttaccc ccgcatccag
     3841 cttgattgac acccgatccc cttcaaagct ttggacaggc ggtcttggat aatcggacag
     3901 aagctgaagc accggtatct cgcctgcaaa gacttccttc caataaacct gatccttctt
     3961 gtacccttca gcagcctgtc tgctttgcca tacagcgtag tccttatact ggagacgaag
     4021 ctcaggaagc tgttcgcctt tataaatgcg tgctaactcc tccagcataa tgccaatgga
     4081 tacaccgtca gaaatcaaat ggtgcatgtc aaacagcagc atatgacggt tctcttcaag
     4141 ccccagcaaa ccgattctga acagcggagc tttcgccaaa tcaaatgtcc gaacgaatga
     4201 agccataatt gcctcatctg agcggccgcc tctttcaatc atttcgatgt tgaaatcaac
     4261 gctatcgtga atgttctgtc tcggcgtgct gttttcaaga acaaatgatg ttctcaatga
     4321 ctcgtggcgt cggattaatc cctgaaatgc gcgctccagc ttttgaatat ctaaaggccc
     4381 ttccagaatt gctgctgccg gcatgttgta gccgactccc gcatcctcga actggctgac
     4441 gatatatgtt cgctgctgtg ccagggaaag cgggtaatgc tcctgttttt cagcaggttc
     4501 aatcaccgca aaagctttgc tttctctgtg atcagcttcc tctgcaagag ccgcaatcgt
     4561 cggatgctca aacaaaaatt gaagcggaat ctcgatgcct gtttccttat gaatctttgt
     4621 taaaagggtc atggccttca atgaatgccc gcccgtttca aagaaattgt caaaaatccc
     4681 cgccttctca acgttcagca cgtcctgcca aatggctgcg attgcttttt cagtctcatt
     4741 tcgcggcgct gtataggcag tgccgctgac agccttcacc tctagtgcaa acagcttgcg
     4801 gcggtcgact ttgccgcttg gcgtaagcgg aatttctgtc acttctgtaa agtaagccgg
     4861 caccatatag tcaggaagct gtctggccgc atgctccctc aaaccggctg gcgcaaattc
     4921 gcttccaggc ttctgcacaa catatgcgca aacctcaaga tttccctgtt cgtcagggcg
     4981 tgccaaaaca acggcttttg caacgtctgg cgcctgctga atcacggctt caatttcccc
     5041 aagctcaatc cggtatccgc ggactttgac ctggtcgtcc tctctgccta aatattcgat
     5101 tgttccatct ggaagccagc gcaccacatc cccggtccgg tacatgcgat cgcccggcac
     5161 gaatggatct tgtaaaaact tttcttccgt taattcaggc aaatgcaaat agcctcggcc
     5221 cacaccgtct cccgcgatat aaagctcgcc cgccacgcct tcaggctgta gccggccttt
     5281 ttgatccaaa atatataagc gattgttccc cagcgctttc ccgatcggca catacgctga
     5341 ttgaactgca ctctcaggga taaccggatg aacagacgcg tcaacgcacg tttcagtcgg
     5401 cccgtataca ttggtcaaac gcggcgctgt gcctgcttct ttaaacagct tcagcagctt
     5461 gtccgcaaca acagatgaca ggccttctcc tccgatcagc atgtgcttca gttttaggcc
     5521 ttcaaaatcg cctgctgctg ccagcatttg caaatgagcc ggtgttccgt ccgtcgcctc
     5581 aatgctgttc ttccgataat atgcagtaag ggcggccccg ttcgtcactg ttttcttcgg
     5641 tacgatataa agggtttgtc ccaaaagaag cgacgcgaag atctgcttca ctgacgcatc
     5701 aaagtggaac ggcgcaagca atgccatccg cagggtttgg ctgccgcttt gataaatcgt
     5761 ctgctgcaga gattcaacca aatgatgaac ctggcgatgc tcgatcataa cgcctttcgg
     5821 gcgtccggtt gtccccgatg tgtaaataat gtaggcaagg ttccgtgcgt tcacatctgc
     5881 attcaggctt tcttctgcac cttccgcaat cgcctgatct aagtcaatca gctcagcatc
     5941 ggcttcaggc gccgcaacct tcgattcagt caggatgaag tccgccccgc aatcctccaa
     6001 aatatattga atgcgctcag caggaaaacc cggatcaatc ggcacatagg ctccgccggc
     6061 ttttaaaatc cccattatag ctgtaatcat ccgttcagaa cgttcaatca aaaccgcgac
     6121 aggactgtcc gggccaaccc ctttttgttt cagcacattg gcgatgcgtg cggattgttc
     6181 atgtaacgtt cgataggaca atgtacgacc ttcaaataca accgctggat gatctgaaag
     6241 ctgctcagcc ttttcttgga acagttccgg gatcgtcatg tccttacggt agctcacaga
     6301 ttcaccgccg gccctcgcaa gcagcttctc tttctccgca tcagaaatca tcgttaattc
     6361 atcaattgta tgttctggat gcgttaacgc gttctccagc atcgtaatca tgcgctcaca
     6421 aatcatgttg atttcttcac gtgaaaataa atcagtgcgg taatcaaaat ctatggtgag
     6481 tttcccagta tcccatcgat ccttcacatg gatcgaaaca tcatttaatc cgctgccgct
     6541 gaaaatcggc tcagtcaaaa aggcaaggtc ctcttctttt tgccattgca tcacctgata
     6601 ttcaagagaa acagtaaaca gcttggtcag agagctcttt gtttcacgca aatcgttgat
     6661 caggagatta tacgggtact tttggtggcg gagtgtcttc atgagatcct tcatccggtc
     6721 tttgacaaat tctgaaaacg cctgcccgcc gtcaatgttt gtccgaagcg gaaccgtaga
     6781 aacaaacatg ccaagcatct gcttctcttt cgcatttgtc cggttgccca taaaggttcc
     6841 cgtcacaaca tcattctggc cgctgaccct gtacaaatag gcggcgagca gcgattgaaa
     6901 taccgaaaga acactgactt tattcgcctc acaaaacgac agaatctgct gatgaagcgc
     6961 ttcaggcaca tctttagaga acctctcagc atctaaactt ccccctgcgg atgcattccg
     7021 tttcagggaa acaagttcag gcaccgattc aaattgcttg ttccaaaacg ccttgtcctt
     7081 ttcaaaccgc ttcgattgag catattcctg ttcagataaa acatgatcga taaatgaatg
     7141 cgagattcct tcttttgtct ctgagccgct ggctaattct aaataaatgt gcatgatcgc
     7201 attcccgaga atattcatgg agataccatc agaaatcacg tgatgaacat ttgcgtaaaa
     7261 ccacacttca ttttccttta tggtgaacaa ggaaaaacgg aacaaatcac aatcgtacaa
     7321 cggcaacggt tttttcgttt cctcccggct ccattgtgaa ataaactcta tcgcattcgg
     7381 atcttcagta gtgtcagtat gttttatatc aacaggccga tactcgctaa tatattgaac
     7441 aggctccccg ttttcatcta gccgcaaccg aaggcgaatg gcgtcatttc tgcgaataaa
     7501 ctcttgaatc gcctgctcaa caagcacata atcaatcgca tcagctgaaa ccagcttacc
     7561 aatccccgca agatttgaaa tgctcgtgtg aggataaaat ttttctgtat accaaattcg
     7621 tttttgtgca tccgttaaag ggtaaaaagt tatttccata ttgtcatacc tcccctaatc
     7681 tttataagca gtgaacatgt gcaacgcatt ttctctttct tatccatatc agcttttaat
     7741 tcttatgaac taacagccga aatagcccaa agtactacac ttaaaaagca gagcttccaa
     7801 acaaaaaaca gattgccgct ataaaaacgg gcagccgtca gtcagcattg cggcgtttaa
     7861 cataagcgga taaagaccgc aagatcccct atcctaacag gaaacaattt tggctattta
     7921 ttcattgttt tcaatatttt ttatcttact accgttcact ttaaatgaaa aaaatgtttt
     7981 tatcaccgaa aaatgggtga aaagtttcat gcgggatgcc gaaagattcc agtttattta
     8041 cagggatatt tttgcgggat accgcaatca tttccactaa acattattta cagaaaaata
     8101 aaaattttta aaccaaactg ctgcgttcaa ttctttttat tgctgactgc aatttacaat
     8161 ctttacatga ctatgtgtac cgcacaaaaa ccgaaaaaaa ggcaaaaaaa agacaccctt
     8221 gcgaagagcg tcttacaacg attctttcat gacatttttg tcgatatcaa tcaattccat
     8281 atagcctttc ccccactcat acatggcttc aagaataggc atgaggcttt ctccgtgcgg
     8341 ggtcagagaa tattcaacct tcggcgggac aaccggatac acttccctgt gaacaatcat
     8401 atcctgctca agctctctca gctgattcac gaggatcttc tgcgtaatat caggaatcaa
     8461 tgtttttaat tcattgaacc gttttgtgcc ttcttttcct aaatgccata aaatgagcat
     8521 tttccattta ccgccaatca ctgcaagcgt taattccttc tcacaattaa accttttgtc
     8581 gtccatccgg ctcaatagaa tcccccctta gtaacctttt tgtatgttaa atacgtatca
     8641 tcacttactt acttttttgc agactctttt ttcattatac tcactcataa aatcaagcga
     8701 aagaaatctg attgcctctc ctcacagtat cctccaagta acttgttgac ttcaaagtgc
     8761 ctacttctca acaaaagagg gaacctatag aatgaacaat aattcgaaaa agggagtgga
     8821 tcaacaatgg aattacagct tgcattagac ctcgtcaaca ttccagaagc cattgagctt
     8881 gtcaaagagg tagaacaata catcgacgta gttgaaatcg gaacaccggt cgtcattaat
     8941 gaaggcctaa gagccgttaa agaaataaaa gaagcatttc ctcaattgaa ggttcttgca
     9001 gacctgaaaa tcatggatgc cggaggctac gaaattatga aagcgtcgga agcaggcgct
     9061 gacatcatca ccgttttagg ggctacagac gacgcaacga ttaaaggcgc agtagaagaa
     9121 gccaaaaaac aaaagaagaa aatcttagtg gacatgatta acgtgaaaga tatcgagtcc
     9181 cgtgcgcaag aaattgacgc actcggtgtt gactacatct gcgtccacac tggctatgat
     9241 cttcaagcag agggcaagaa ctctttcgaa gaattaacga caatcaaaaa caccgtaaaa
     9301 aacgcaaaaa ccgcaatcgc gggcggcatc aaacttgata cactgccaga agtgatccag
     9361 caaaagcctg accttgtcat tgtcgggggc ggaattacaa gcgcagctga taaggcggaa
     9421 acagcttcaa aaatgaagca gctgattgcc caaggataac tccgatgaaa acgactgaat
     9481 acgtagcgga aattctcaat gagttacacc gttcagcagc ttatatttct aatgaagagg
     9541 ctgaccagct tgccgatcac attctttcat cccaccaaat tttcactgcg ggtgcggggc
     9601 ggtctggcct gatggcaaaa tccttcgcga tgagattgat gcacatgggc ttcaacgccc
     9661 atatagtagg tgagattctc actccgccgc tcgccgaagg agatctagtt attatcggct
     9721 caggatcagg cgagacaaag agcttgattc ataccgcagc aaaagcaaaa agcttacacg
     9781 gaattgttgc cgctttaacc atcaatccgg aatcaagcat cggaaaacaa gcggacctca
     9841 tcatcagaat gcctggttct cctaaagacc agtcaaacgg aagctataaa accattcagc
     9901 caatgggatc attatttgaa caaactttgc tgctcttcta tgatgcagtg attttaaaac
     9961 tcatggagaa aaaagcactc gattctgaaa ctatgttcac tcaccacgca aaccttgaat
    10021 agcatcacac aaccggcctg aaaatcaggc cggttttatt tttttaaaaa taaaacttta
    10081 aacccaaaaa cccgataagt aatatgacct ataaatcata aaaggaggaa ttatgttgat
    10141 aaaacgattt aagatgaagc taggaactaa aattctttgc ctcgttttcg tggtgattct
    10201 tttgttttcg gcatcagttg gcactgtgat gcttaaagaa attacagaaa gcatgaaaca
    10261 aatggcaact gaaaaagcga aaggtgatct cgctttaagc agcacatata ttgatgatgt
    10321 catgtcaggc gactggcagg tgaaaaacaa taagctctat aaagggcaaa cacaaatcaa
    10381 tggaaatgaa gatattgttg atctgcttgg tgaaaaaaca ggtgatacca ttaccatttt
    10441 ccaaggcgat actcgtgttg caaccaatgt catgaagaat ggcgaaagag ctgtcgacac
    10501 ccaggcttct tctgaagtta tcgccgctgt tttaaagaaa ggaaagcgtt tttacggaca
    10561 agcagatgta gcaggttctt cttatcagac tgcatacatg ccgttaaaag atcaaaatgg
    10621 gaacatcatc ggcatgctgt ataccggagc taatcaaagt attttagcat cacttacaca
    10681 atcacttttc actcaattcg ctatcgttct tgttatcgtc attatagtat cagtcatcct
    10741 tgttttggtt ttcaccagaa aaatcaacaa gcggctgaac gctttaaaaa gcgcctttga
    10801 aagtgccgga aacggagata tgacaataga ggtgtcagac aaaaccggtg acgagctttc
    10861 agaactaagt gtctattata ataagatgag aatgaagctg aacgatacca tacaaaccgt
    10921 acaacaatca gcccttcagc ttgcgtcagc ctctcagcaa ctctcagccg gagcagagga
    10981 aacaaatcaa gcttcagaaa aaatcacaga agctgtacag cagattgcaa atggagccca
    11041 agatcagatc acccgaattg aaaacagtga aagctcttta aaacaagctt cagcagacat
    11101 ccgggatatt tctgcaaata ctgccgctat cgctgacaaa gggcagctcg cgcaatcaaa
    11161 agcagacatt ggacaaaagg aaattgcaaa tgtacaggcg caaatggatg cgattcacca
    11221 gtcaattcag aaaagcggag aaatcataca ccagttagac ggccgctcta aacaaattga
    11281 gcaaatttta tcggtcatca cccaaattgc cgatcagaca aacctgcttg cgctgaatgc
    11341 agcaattgaa gctgccagag ccggtgaaca aggaaaaggc tttgctgttg ttgctgatga
    11401 agtacgtaaa ttagcggaag agtctcaaca gtctgcggga cagatttcaa aactgatcat
    11461 agaaatacaa aaggatatga atcggtctgc aagatctgtt gagcatgtga aaacagaagc
    11521 tgcagaagga gtcaccatga tccagcgcac cagagatgca tttaaggaaa ttgcagctgc
    11581 aacaggtgaa atcagcgccg agattagtga tttatcagca tctgtaacaa acatttcagc
    11641 cagtgcacat catataaatg attcctttgc agccaatacg gccgacatta aagaatctac
    11701 taaaaatacc cggcaagcgg ctgcattaac agaggagcag tttgctgcaa tggaggagat
    11761 taccgcagct tctgaaacac tttctcaatt agctgaagag cttaccggta tcataagcca
    11821 atttaaaatg attaatcaag ccgcaaacgg ctgatgactt actatcatta ttgtaaattg
    11881 gcaatcgtat tttgcttaaa acaaatattt cgatctgcta aaattacgat ttctgcaata
    11941 aactgagcgt aaaacataaa atttaaacct ttacaccaaa tgctttctgg attactcttg
    12001 tgtcagtttt aaaagcggga ggtgaacatc acgacggaca tcataaaaac aatacttctc
    12061 gtcatcgtca tcatagcagc tgcagctgtc ggcctgataa aaggagactt tttctcagct
    12121 gatcaaaaaa cgtctcaaac gaaagaatat gatgaaacaa tcgccttccc ttctgaccgt
    12181 tatcccgaaa cggccaagca tattaaggat gcgataaatg aggggcactc agaggtgtgc
    12241 actatcgaca gagacggagc tgaggaacgc cgcgagcaat cattaaagga cgtaccttcc
    12301 aaaaaggggt atgacagaga tgaatggcca atggccatgt gcaaagaagg cggtgaggga
    12361 gcttctgtag aatacatttc tcccgctgac aaccgcggag caggctcttg ggtcgggcat
    12421 cagcttaccg attacccaga cggcacaaag gttttattca caattcagta aacagtacat
    12481 agaggaggaa cagcacattg atcaaatcat ggaagccgca agaactttcg atttcatatc
    12541 atcaatttac tgtatttcaa aaggattcta cacctcctgt aatggattgg actgacgaag
    12601 cgattgaaaa aggatatgct gcggcagacg gagccatttc ctttgaggca cagcgaaata
    12661 caaaggcctt tattcttttg cgcctgaaca gttcagaaac agtaaactcc tacgaaaaaa
    12721 aagtgactgt tccttttcat gtcacagaaa acggaattca tattgaaagc atcatgtcta
    12781 aaagactgtc ctttgatctg cctaaaggag actatcaatt gacatgctgg actgtgccgg
    12841 ctgaaatgtc agatttgcac gccgacactt atattattga tgctgtttct gtgtaatgaa
    12901 aaacccctga gagaataact ctcagggact ctttataaac tttctccgtt tgtcttgatg
    12961 acatcttgat accaataaaa gctttttttc ttcaagcgtt ttaaatcgga tgtgctttct
    13021 tcatcacgat tgacatatac aaatccgtat cttttttggt agccgttcag ccagcttaac
    13081 agatcagtaa acgaccagct gcaatagccg attaaatcga caccgtcact gatggcttgt
    13141 ctgcattgct caagatgcga acgcaaataa tcaattcgat aatcatcctg tacagtgccg
    13201 tcttcaactt tatcaaattc acccaaaccg ttctctgtta taaacactgg aagctgatag
    13261 cggcttgtaa ttcggcgaag accgatacgc agcccaattg ggtcaattgt ccaatcccag
    13321 ttgctcgttg tcagatgcgg attttttttc gttttgaaca ctccgggtat ccccgtctcc
    13381 tgattggttc ctttttggcc tgtcgtattc attttccctt ctgacacacc atcaagcgga
    13441 tttcgttcat aggtgatcgt ctgataataa ttgacaccta caaaatcagg cttccctttg
    13501 gcgagcaggt ccatatctcc tggttcaatt gtcggcgccc atccctgttt ttccaagtag
    13561 cggaatggaa tttgcgggta ggttccccag caatacatgt caagccacca attgttcgta
    13621 aattcttcgg cgttttcaaa tgccagtata tcctctggat ggcttgataa agggtaagcc
    13681 ggagaataag caaagctagg gcctattttg ccttcaggca catattctct aaatgattcg
    13741 atggcttttg cattagccag aaacgcaata tggtttgctt cgtaaaatcg ttttctgtct
    13801 ttcactccag gcggatgcat ggctgtaata aatccgtgat taaaattgta gttctgttcg
    13861 tttaacgtaa cccaatattt caccctgtct ccaaaacgtt tataaagagt aatacagtag
    13921 tgattaaaat cctctatgat gtttctggat tcaaacccgc cgtattcgtc cataagcgct
    13981 tgaggcaaat cccagtgata taaagtcaga accggctcga tgtgatgaga aagcaattca
    14041 tcaatcagtc tatcgtaaaa cgctagacct gcttcattga tctctccttt tccttttgga
    14101 aaaatccgtg gccagctgac ggaaaatcga tacgctttta accccatctc agccatcaga
    14161 gcgacatctt ctttaaatcg gtgataatgg tcaaccgcaa tgtcgccatt ggttccttta
    14221 aacgttttgc ccggtatttt cgtaaacaca tcccaaacag aagggccttt gccatcttca
    14281 ttccaagcgc cttcaatctg gtacgctgca gaagcagagc cccacaaaaa atgtttcgga
    14341 aaagattctg gatgctggtg gatcatagtg tttatcactc ctgaattatt gataaaccta
    14401 tcataggcta tgaaacgcgt ttcagatcaa ctcgatgtta gtcgcggaac agctcagcta
    14461 atattttttc tctttgtcca agaaaatatc gtgttaattg aacatgctct gtattctcat
    14521 attcaatatg atgtattctt ccaccatcaa agcttaaaat attagcattg ggatagccca
    14581 gtaggattgg ggagtgagtc gcaatgatca tctgtacatt tccgcccttc accaaatcat
    14641 gtataactct caaaaaagct aattgtctag ctggagaaag tgctgcttct ggctcatcta
    14701 aaaggtaaat cgctttctct ttaaaacgat gacggaatag agacataaag gactctccat
    14761 gtgattgatt gtgtagcggc ctccctccat aggaacggta tggctgagga gcatctagtt
    14821 ccatctcatc cagatgaaga gaaagatgat aaaacgattc agcccttaag aagaagccat
    14881 ttgttacctt tggaagccaa gataaacgta tataatctcc taaatgggaa tctgactccc
    14941 gtaattcata gacattattt cggcttccgc ccgctgtatt gaattcacac ttatctgcta
    15001 tcgcttcaag caaagtagat tttccagatc cattttcccc cacaaaaaaa gtcacttggc
    15061 tagtaaataa gatgtcattt aattgactta tagccgggat agtaaaagga aatctgtcaa
    15121 agtccaaaat cttatctcga agaagagtaa ccttttttaa aaacatagca tctcctttct
    15181 atactcagtt aaataatata ttgagaaaga tcttctgcat ccataaaaac atagcccatc
    15241 ctagtattcc aacacataat gcaaaccaaa acggcacatg aattttcagc aaaaaagcca
    15301 aaatagctag taaacaaact gtagctggga ttcctgtaag cacaccagat gcaaattgac
    15361 ttaattgagc tgttttttca ccttgtattt gcatccaaaa aaggcttaat aaactgacca
    15421 agggcaaagc agcaatgatg ccgccatagg tcggatgtct ttttgatatt tcagtaacaa
    15481 aaccgataat caacgcagag atgattactt tacttaaaac tgccattgtt tagcttccct
    15541 acttaaaagt tcaaatgcct gttcaagtaa tttcttttct gatgtgctca ttcgttcaat
    15601 tatttctttt aatttctctt tatctagctg tgtatgctgt tcaagaacag atcttccttc
    15661 ttgtgttaag aaaactaaaa cttttcgttc atcctgttga cttcgccgtt tagctataaa
    15721 tcccttttga atcaaacgtt tagtatgctc tgacgctgta ttgtgagaga cagacaagta
    15781 ttcagccaaa gctcctattg tcgcctcacc ttgcttttca atatgctgca taatccgtat
    15841 tgcctggtga gaaatattat ctttatgttg ataatgtaat aaataataaa tatctgtcca
    15901 ctgctgatta agtttagaga ttaaatccat ctccatcatt atacacccca tttgtatctt
    15961 attataagat ataatcaaca aaagcgatat attttttgga aaattcattc agtaactttt
    16021 aacaataaaa aagcacccaa ttcccattgg atgcttacca ttttaatgtc ttttttcaaa
    16081 tttatgcgga tgaggatggt gctttggaac aaagccgttt tgtttcatca tttcaaagtg
    16141 tttgtccaag tgatttttga tgtgttctcc tctttcttta ggcaggacac catattgtac
    16201 atactttgag atcacgtctt tgcgcttttt aagaatctct gcttccagtt gttcaatctc
    16261 tttcttttgc tgatctgtca gtgtaacatt tgcgggaggc tgctgctgtt tttcagcggc
    16321 ctcagctgta ccggtcagag aaatgacagc cgctgcaatg aacattgtga tgatgttgat
    16381 ggttattcgt ttcatccagt ttattcctcc aatctatttt tcatatgttt tgctgccttg
    16441 tattttttat gcataaaaat aaaaagagcg aaccattatt cgctctttct aatctcttcg
    16501 tcagcattaa gttcttcttc acctggcgtc gcataagtga catacgttcc cgcgattaaa
    16561 tcatgcaggg tccgtttgtc ttctcgtacg gcaattagaa tcaggctggc gatcaagccg
    16621 agtccgaagg ttataacgta aaccaggccg gctacaataa cccgtaaaaa cattgttaac
    16681 aagctgactt gtgatccgtc ttttttttac gattctgatt ccgcagattc tttttccgat
    16741 aaggtagccg cgccaaaaca ccggcagcaa aatagagtac agcagaacaa ccaaactgat
    16801 gaacatgctg tcattcgggt cttttcctgt aatcagccaa tagatcagca aaagaggcac
    16861 ggagactata atgtagtcta acaatgcagc tccaagtctg atccaatatc cggctggttt
    16921 gtaaatgttc atttgactcc ccattatggt ttaaatgttt ccattttctt tctcatcgaa
    16981 tatatcatat gccttagggg catcagcaag acttaaatta ttctgatgat cggtttcatg
    17041 tctcttgacc atttcttccg gtattggcat agatgagtga cgggtctgct gcatccttca
    17101 ctttcacatg tgtttccttg gtacgtctgg cattcatcct tggacaattc cttttttcat
    17161 cacctcttcc cttcatagac gcttttaaac acccacccat gtcttttgta tacacaattc
    17221 gaactttttg aaaacgcgat caacatattg caacccctta tgttcaatgc tatcttttta
    17281 gttgattaac agattggggg aactataggt gaaatcattc atgcattcca aagccgttat
    17341 attcagtttc acaatggctt tctttcttat attggcagcc tgttccggca aaaatgaagc
    17401 cgattccaag gatacaggct gggagcagat taaggataaa gggaaaatcg tagtcgctac
    17461 atcaggcacg ctttatccca cttcttatca tgataccgac tctggctccg ataagctgac
    17521 aggctacgag gttgaagtcg ttcgtgaagc ggcaaaacgc ctgggattga aggttgagtt
    17581 caaggagatg ggcattgacg ggatgctgac agcggtgaac agcggacagg ttgacgcagc
    17641 cgcgaatgac atcgatgtga cgaaggaccg cgagaagaag ttcgcatttt ctactccata
    17701 taaatattca tacggcacgg caatcgtccg taaagacgat ttatccggga ttaaaacgct
    17761 taaggattta aaagggaaga aagcggctgg cgcggctaca accgtctaca tggaggtcgc
    17821 gagaaaatac ggcgccaaag aagtgattta tgataatgcg acgaatgagc aatatttaaa
    17881 agatgttgcc aacggacgca ctgacgtcat tttaaacgac tattacctgc agacacttgc
    17941 gctcgcggca ttcccggatc tcaacattac aattcatcct gacatcaagt acatgccgaa
    18001 caaacaggcc cttgtcatga aaaaaagcaa tgcggcactt cagaaaaaga tgaacgaagc
    18061 attgaaagag atgggcaagg atggttcttt gactaaactg tcgaaacaat tcttcaataa
    18121 agcagatgta tcaaaaaaaa ttgatgccga cgttcaggac gttgatttgt aatcggacgc
    18181 catgatcaat agcattcaat gggaatatat tttcaacaca aagctggcta ttgaatcgtt
    18241 cccttatgtc ataaaaggca ttgggtatac actgctcatc tcttttgtaa gcatgtttgc
    18301 gggaactgtg atcggcctgt tcatatcact cgccagaatg tctaagcttg ctttgttaag
    18361 atggccggcg aagctctata tctcatttat gcggggcgtt ccaattttgg tgattttgtt
    18421 tatcctttat ttcgggtttc cttatatcgg cattgaattt tccgctgtca cggctgcttt
    18481 aatcggcttt agcctaaaca gcgccgccta cattgcggaa attaaccgtt cagccatttc
    18541 atccgtcgaa aaaggacagt gggaagccgc atcctcgctg ggtctttcct attggcagac
    18601 gatgaggggc atcattttgc cgcaatcgat acgtattgcg ctgcctccgc ttgccaatgt
    18661 gttgctcgac ttaatcaagg catcatctct cgctgcgatg attacagtgc cggaattgct
    18721 ccagcatgcg aaaatcatcg ggggcagaga gtttgattat atgaccatgt atattctgac
    18781 cgctctcatt tattgggcca tctgctccat tgccgcggtc tttcagaata tccttgagaa
    18841 aaaatacgct cattatgttt aaacaaacgt ttcattaaaa aaagccgccc ccaggggacg
    18901 gctttttttc tattgattca gcttccattt aaacgggtcc tcaaacagcg accagtcgga
    18961 atcaaattca tattcagtca gcaggcattg atcaagctct ttcgtaatcg tttcttcatc
    19021 caggtcagtt ccgataaaaa ctagctgcgt taggcggtcg ccgaactccg ggtcccactc
    19081 ctccaggatt tccggctctt gctgtttgac ttgctcctgc tcaagcttcg gcagcgccgc
    19141 cacccaataa gatacaggct caatcgtaac cgacggacct gcttgcgaca tcagcaaagc
    19201 aaggttgtta tgagatgcgc accagacgat tcctttggca cgtaccacgt tctttggcat
    19261 ttgatccaac caacggtaaa atcgtgtaga atgaaacggc aaacgtctct tatatacaaa
    19321 tgaagagata ccgtattctt ctgtttccgg gatgtgttcc gcatggcctg ccgtcagctc
    19381 ttgaatccag ccggccgatc cgctcgcttc ctcgaagtta aataaccctg tatgcaaaat
    19441 ctcctgcggt tttacatttc ctttgacgga acgaatgaac ctggctcttg gctgcagttt
    19501 acgaagaacg ttttcaagct gttcgagctc ttgctcgctg accaaatcac atttatttaa
    19561 gatcagtaca tcgcaaaact caatttgatc gatcaagagg tcggcgattt ctctttcatc
    19621 ctcttccccc aatgcttctt tgcggtccag aaggctttca cctgactgat aatcatgcca
    19681 aaaacggttg gcatcaacca ctgtcaccat cgtatccagc tgacaaaatt ttgtaagatc
    19741 gattcccatc tcttcatcga tataagagaa agtctgggcc accgggatcg gttcgctgat
    19801 tcctgttgat tcgatgacga tataatcaaa ccgtccgtct tttgccagct tctcaacttc
    19861 aattaataag tcttcgcgaa gcgtgcagca aatgcagccg tttgacattt ccacaagctt
    19921 ttcatctgtt ctggaaaggc ccccttcctg cttgaccaag cccgcgtcaa tgttcacctc
    19981 gctcatatcg tttacgataa ccgctatttt caagccttcg cgattttgca gaatgctgtt
    20041 cagcaatgtt gtttttcccg cacctagata accgctcagt acggtaaccg gaattttttt
    20101 cataatagtg cctccattaa aatagaatga ttacgattta aattgaatac ttcgccgtat
    20161 gtacaatggt gtagagcagc ttttcgcgct cttttctcgc tccacccgat ttctaaatca
    20221 gtaaaggctc caaccgcgtt taatcctttt tccccatcgc aaatccttgc cgacagcaag
    20281 atccttaatc gatgcctttc cgctttttca cagatgcaca gccaatgata agccatttat
    20341 cacaaaacgt aatagttacg atttaaattg tatggtcttt tttccttttt gtcaacgatt
    20401 ttcaattcag ctgatcacca cttttgtatg ttcagggata ttttcatata cccatttcgc
    20461 atctggaatg gtcagcctga tacatccgtg agatgctttc gttcctagtt tttctgcttc
    20521 cgttttgatg actttttgat ccttagtcat tggcacacta tgaaataaaa attcaccgtg
    20581 atttttccat gatacccagt attctgcgcc ttcctggtat ccttcggaga aaaaccattc
    20641 tccccgttca ggctctacat aaaaggtgcc ctttggcgta gcatcatctt ttgtttgatc
    20701 aagaccagaa gagatcatca ttgtatagat ggtgttgctt ccttccttga tgtaagcctt
    20761 ctgctccttc acattcacat caatccagac atgcttctgt ttaatatccg ggtattctcc
    20821 gcccgaagac tttgtccaat caatgcttgt ttttgctgtt tttcgaacgt ccgttatgtt
    20881 tttgaccgtt ttctttgtat tgatacttgc gtgttcttct gcatggtcgg agcaggctga
    20941 cagcaggctg gctggcataa gaactgcaat aatgaataat gagagtttca tattttatcc
    21001 acttccttcg aaaaacacag cttcgcatag gcatcgtgga gatggatcga ttcttcattg
    21061 cggcattcaa tctcaaaggc agacacccat tcaagctcaa acaaatctgc agcaatcagc
    21121 cgggcgagat cctcaacaaa cctcggattt tcataggccg tttctgtcac ggctttttca
    21181 tcaggccgct tcaataccgg atacagtctc gcagaagcat ttgattctgc ggcgtgaagc
    21241 aaatcagctt taacatcact tggcagcgat gcggccggat gaatatccgc ccaaatgctg
    21301 accgttcccc tctgattatg ggcactgtat tcgctgattt ccttggagca agggcacaga
    21361 gtcgttactt ttgctgagat gccggcacgc tgtttaaacg gctgatcttt gcgataggtg
    21421 acagacatga atatatcagc atgcatcaaa cccgctttct caagcttcgg gcttttccgt
    21481 tcgaaaaacc acggaaacct cacttcaact gtggcagatg atatgtccat gttttctgca
    21541 agctctttcg taaattgctg aagagaggaa aatgagagaa cccagccgtt ttgatgatag
    21601 acttgcagca gctctgttaa ccggctcata ttaatcccct tctgatttct cggcaaatta
    21661 caagtcattg taaagttcgc agccgttgtt tgctcggcag gcatcatggc agaagtgatt
    21721 gtcactggat gggacacatt agcgacacct acatgctgaa tgtcaaaaaa ataatccttc
    21781 ctgatatttt gcaggtcctt cattttctct ttttccactg gtttctcgcc tttgatcgga
    21841 ctgaccgatc caaagtattg aagacgctcc gtttttttcg ggagcagcgt atgttgattc
    21901 attcagaaaa ctcctctcac taacaaatcg taataattac tatttatttt gatcggttca
    21961 ctgttggaaa tcaagagaaa ataaaaaaga cacgcacaaa tgcgtgtccg tcaaaatcct
    22021 aaacatccgc cgggctgctt tccgcgctcc agcttttccg ccagtaatag cctgcggcaa
    22081 gcacaagtgc aaacgccagc agcgcgatac aggaaaacgt gataaaaccg atagcatatg
    22141 tgcctgtcat ctgtttgaga gatcctaaga tgttcggcag gaaaaaccct ccgattcctc
    22201 cggccgcacc gacgattccc gtcaccatgc caatttcttt gcgaaaacgc tgcggcacga
    22261 gctggaatac tgcgccgtta cccattccga gccccatcat tccgacaaac aatagaacaa
    22321 taaccattga aagagatggc aggctgctga ctccggccat acacagtgcc acgatgacaa
    22381 acagtacaga aagaactttc gtgccgccga cacgatccga aatcaagccc ccgacaggcc
    22441 ggaaaaagct ccccgccgcc acacataatg taacgaagtc ccctgcgtga atttttgaca
    22501 gctggtattg atcaacaaag aaaatagata aaaagcttga gagcccgaca aatccgccaa
    22561 atgtgacgct gtacagcagg cagaaaaacc atgtttcctt ttgcccgaac acatgcagat
    22621 agcttttaag cggctgcgga gccggctgtg caggagaatc ctttgccatg gatacaaaaa
    22681 gaataaagac gatcaataat ggaattagcg caattcccat gacaatgtgc cagccgaact
    22741 gctctgccag acgagggcca aacaaggttg caaacaacgt gccgctgttc cccgctccgg
    22801 caatccccat cgcaagtccc tgcaaatgag gcggatacca gcggctggcc ataggcagcg
    22861 ctacagcaaa gcttgccccc gccacgccaa gcagaatccc gatggcatac agctcagtca
    22921 gggaacggcc gccgaatgtc ccccaaagca gcggaatcat cgtcaccagc atcccgatca
    22981 ctgccgtttt tttcggtccg attctgtccg ttaaaatacc aagaatgata cgaaacactg
    23041 atccagataa aatcggcaca gctacgacaa gccctttctc aaaaggagac aggccaaaat
    23101 cctgagaaat ataaacaccc agcgccccta gcataaccca tatcataaaa ctgacatcaa
    23161 agtataaaaa ggaacagagc aaagtgagtg gatgaccgct agttttcagt tccgacagct
    23221 tcataagatt cccctttcta gaccctcatt attttacatt ttctgaatca aggatatagg
    23281 accattattt tctggaaaag acatgtgtaa gtttttgtga cacgtttaat gcgttaacag
    23341 tgcattgtga cataattttt aataggagaa aacttacgag cttcgccaaa ggaggtctga
    23401 tacatgaaga aacaaagatt ggtgttagcg ggaaacggca tggccggaat ccgctgtatt
    23461 gaagaagtat taaagctgaa tcatcacatg tttgagattg tcattttcgg aagcgagccg
    23521 catcccaatt acaatcgcat tctcttatcc tctgtattgc agggtgaagc gtcactcgat
    23581 gatattacac tgaacagcaa ggattggtac gacaagcacg ggatcacgct ttacacaggc
    23641 gaaacggtta ttcagattga tacagatcag cagcaggtca tcacagatcg gaaacgcact
    23701 ctgtcgtatg acaaattaat agtggcaaca ggttcctccc ctcatattct ccctatcccc
    23761 ggggcagaca aaaaaggtgt ctatggattt cggacaatag aagactgcca agcgctgatg
    23821 aagatggctc agcactttca aaaggctgcg gtaatcggag ccggcttatt aggactggaa
    23881 gctgcagtcg gtttacagca tctcggtatg gatgtcagcg tcattcacca ctccgccggc
    23941 attatgcaaa aacagctcga tcaaacagcg gcgcggctgc tgcaaacaga gctggaacaa
    24001 aaaggcctaa cctttcttct ggagaaagac accgtctcca tttccggcgc caccaaggca
    24061 gaccgaatcc attttaaaga tggctcttca ttaaaagcag acttgattgt gatggcggcc
    24121 ggcgtcagac cgaatattga attagctgta tccgctggaa tcaaagtgaa ccgcgggatc
    24181 atcgtgaatg acttcatgca gacaagcgaa ccgaatatct acgccgttgg tgaatgcgcc
    24241 gaacataacg ggacggtgta cggattggtg gcaccgcttt atgagcaggg aaaagctctc
    24301 gccagtcata tttgcggcgt tccatgtgag gaatatcaag gctcagcacc atctgcggct
    24361 ttaaaaatag ctggaatcga tgtgtggtca gcaggaaaga tccaagagga tgaacgcacg
    24421 acgagcatca aaatctacga cgaacaagca ggcgtttata aaaaagcgct ttttgtagat
    24481 gacaaactgg ccggtgttat tttattcgga gacacccgtg acaagcagcg gcttctcgac
    24541 agcctgctta aacaacgaga catctccatt gtcaaaaagc agatcatcga accggagaca
    24601 agcggccctt tattagaatc catgccttcc agtgaaacga tttgccaatg caacacagtg
    24661 acgaaaggcg cgattgaaga cgcggtgcac acgaatagct taacaactgt tgaggaagtc
    24721 aagcactgca ccaaagccac tgggtcctgc ggaggatgca aaccgctcgt tgaagacctt
    24781 ttgaggcaca tgaccaacag cgaatatacg aagcccgccg gcacaccttc gttttgcagc
    24841 tgtactgatt ttacagaaga cgacatcatc gctgagcttc agcgcaggcc attcactaat
    24901 ccggcagaag tgatgaacca gcttgactgg agaacaaaaa aaggatgcag tacttgtgtt
    24961 cctgcgattc aatactatct ggaaatgctg taccccgggt ttgtccagcc tgagccagcc
    25021 actgaagaga catgcatcct gattccgcaa atgtacggcg ggcggacaaa cgcggagcag
    25081 ctaagaacca tcgccaacat cattgaggca tacagcattc ccgacgtatc catcactcac
    25141 ggccaaaggc tgaagctttc cgggatcaag cctgcggatc tcccgaacat aaaaaaagac
    25201 ctgaagatgc ccgtttacac taatgaacac cgacacgcgc tgcaaagcat caaagcatgt
    25261 acatgcgggc aaaatcgatc gattcagcag ctggcagccc aaatcgaaag acaacttgag
    25321 acgcttccct tacccgctcc catttctatc agcttatcat gtgaaacaga ctgcaccgat
    25381 gccgccctgc aagatgtcgg cgcaattcgg acacaagctg gctgggacat ttacatcgga
    25441 ggcgtccggg gaactcatgc ccgttcagga gctctgtttt gcgtgactga gaacgaagac
    25501 agcactgccg gcatgatcaa aggactgatc cagtattatc gggaaacggc tcattactta
    25561 gaagctgttc atcagtggat agaccgtctc gggatcgttc atatcagaga agtgctattc
    25621 gaagaagacc taagggcaca gctgctggaa agcctccaaa cagatctgtc actgattcaa
    25681 aacccgactg tagagacggg tgcatataag aaaggatgag gcattttgac tgaacgactg
    25741 cttagatatt tccgtgataa acagcaagac gtccaatcag aaaaaacata tgacactcaa
    25801 tgcccgtttt gcagcatgca gtgcaaaatg cagctcgtgg aacaaaccat cgtcacgcgc
    25861 aaaaagtaca ctgcgatcgg gattgataat cctacaacac agggtcggct atgcatgaag
    25921 ggcatgaacg cccaccagca tgccctgaac tcctcccgca tcacccggcc gctgctgaag
    25981 aaaaacggcg agtttatgcc tgtttcctgg gaagaagcac tgaattacat taaagaccaa
    26041 gtgacaatga tccaagcaga acacggccat gacgctatgg cggtatacgg aagcgcctcg
    26101 attacaaatg aagaggcgta tttgttaggg aaattcgcac gggtgggctt acagacaaaa
    26161 tacatcgact acaacggaag gctttgtatg tccgccgcag caaccgcagc caaccaaaca
    26221 ttcggcgcgg acagaggctt aacgaatccc ttatcagaca ttccccacac ccgtgtgatc
    26281 attctggccg gcaccaatat cgcggagtgc cagcctacga ttatgccata ttttgaaaaa
    26341 gcgaaagaaa acggagctta catcattgcc attgatccgc gtgaaacagc gacaacaaaa
    26401 atcgccgatc ttcatttgaa aatcaaaccc ggcacagacg ccgctcttgc caacggtctc
    26461 gtcaaaatca tcatcgacga acagctcgca aaagaagatt ttattcaatc acgaacaaat
    26521 ggattcgaag agctgaagca gtatactgac tcgttgaacc tgaatgacat cgccgaacag
    26581 acgagtgtcc cgctggtgga tataagaaaa gcggctgtaa agtttgccaa ggaaacgtcc
    26641 ggcatgctgt ttacagcccg cgggattgaa cagcaaaccg atggcacagc ggctgtgaaa
    26701 ggcttcttaa acatggtgct gatcacagga aaaatcggca agccttactc aggttacggg
    26761 gcgatcaccg gacaaggcaa cgggcaaggt gcaagagagc atggccaaaa agccgatcag
    26821 cttccgggct atcgatctat tgaaaacgaa caacaccggg cacatgttgc gaaagtgtgg
    26881 ggaatccatc aggatgatct gccgcgaaaa ggtgtctcag cctatgaaat gatggaaaaa
    26941 atcaacgacg gcgacatcaa aggattgttc ctcatgtgct ccaatcctgc tgtctccagc
    27001 ccaaatgcga atctcgtgaa aaaggcttta aggaaactga cattctttgt tgcaatcgat
    27061 ttgtttattt ctgagactgc gaaatacgca gatgtgattt tacctgcctc ctcttactta
    27121 gaagatgaag gcaccatgac aaatgtagaa ggacgcgtga cattaagaga agcaagccgg
    27181 ccatgccccg gcgaagcaaa gcatgattgg cagatcattt gtgatctcgc atccgctctc
    27241 ggcaagggcc gctacttttc ttatacgtca gcggaggata tttttaatga attgagagaa
    27301 gcgagccgag gcgggattgc cgattattca ggcatctcat acgacaggct cagacgtgaa
    27361 ggcggcattc attggccgtg tccggaatct gatcatcccg gaactgggcg cttgtttaca
    27421 gaatcatttg ctcatccgga tcaaaaagcg gcattaagtg tgattccaaa cgaaccacct
    27481 gttccaaaag agaagccgac agccgattat ccgctttatt taacgacagg cagagtcatg
    27541 tctcactact taacaggcgt ccaaacaaga aaaagcgccg cccttgccgc gagacatttt
    27601 gaatcgttta tggaaatcca tccgcaaaca gcagcgacct acaatatcga ggaccgtgt
//
