LOCUS       NZ_NJRE01000002        20747 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain 18-3 18-3_R1_(paired)_contig_2, whole
            genome shotgun sequence.
ACCESSION   NZ_NJRE01000002
VERSION     NZ_NJRE01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 904110)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 904110)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010578165.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:36:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,453
            CDSs (total)                      :: 4,376
            Genes (coding)                    :: 4,252
            CDSs (with protein)               :: 4,252
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 5, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 1, 5, 2 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 72 of 124
            Pseudo Genes (incomplete)         :: 64 of 124
            Pseudo Genes (internal stop)      :: 16 of 124
            Pseudo Genes (multiple problems)  :: 23 of 124
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:28:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 267219
            Orig. end                         :: 287966
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NJRE01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20747
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="1"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20747
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10747](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10747)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(436..1368)
                     /gene="hprK"
                     /locus_tag="CE047_RS05955"
     CDS             complement(436..1368)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hprK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391380.1"
                     /locus_tag="CE047_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="WP_003228097.1"
                     /transl_table=11
                     /translation="MAKVRTKDVMEQFNLELISGEEGINRPITMSDLSRPGIEIAGYFT
                     YYPRERVQLLGKTELSFFEQLPEEEKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEK
                     NGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETA
                     LELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRS
                     NKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMN
                     FRLKRMGLNAAEQFTNKLADVIEDGEQEE"
     misc_feature    1480..1495
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            1550..2740
                     /gene="nagA"
                     /locus_tag="CE047_RS05960"
     CDS             1550..2740
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391381.1"
                     /locus_tag="CE047_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_038829910.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.1e-43, bitscore:
                     144.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESLLIKDIAIVTENEVIKNGYVGINDGKISTVSTERPKESYSK
                     EIQAPANSVLLPGMIDIHIHGGYGADTMDASFSALDIMSSRLPEEGTTSFLATTITQEH
                     GNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVALFKK
                     WQQEAGGLIKIVTLAPEEDQHFELIRHLKDESIIASMGHTDADSAMLSDAAKAGASHMT
                     HLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIHSHPLAAKLAFLAKGSSKLILITD
                     SMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTLAGSILKMNEGARHMREFTNCSWTDIA
                     NITSANAAKQLGIFDRKGSVTVGKDADLVIVSSDCEVILTICRGNIAFISKEADQI"
     gene            2737..3465
                     /gene="nagB"
                     /locus_tag="CE047_RS05965"
     CDS             2737..3465
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391382.1"
                     /locus_tag="CE047_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_038829909.1"
                     /transl_table=11
                     /translation="MKVMECQTYEELSQKAARITADTIKEKPDAVLGLATGGTPEGTYR
                     ELIRLHQTENLSFQNVTTVNLDEYAGLSSDDPNSYHFYMNDRFFQHIDSKPSRHFIPNG
                     NADDLEAECRRYEQLVESLGGTDIQLLGIGRNGHIGFNEPGTSFKSRTHVVTLNEQTRQ
                     ANARYFPSIDSVPKKALTMGIQTILSSKRILLLISGKSKAEAVRKLLEGNISEDFPASA
                     LHLHSDVTVLIDREAASLRP"
     gene            3483..4214
                     /gene="nagR"
                     /gene_synonym="yvoA"
                     /locus_tag="CE047_RS05970"
     CDS             3483..4214
                     /codon_start=1
                     /gene="nagR"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="yvoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391383.1"
                     /locus_tag="CE047_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylglucosamine utilization transcriptional
                     regulator NagR"
                     /protein_id="WP_003228089.1"
                     /transl_table=11
                     /translation="MNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFG
                     ISRMTVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRL
                     IDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHIPFELAGELNESHFQ
                     SSIYDHIERYNSIPISRAKQELEPSAATTEEANILGIQKGAPVLLIKRTTYLQNGTAFE
                     HAKSVYRGDRYTFVHYMDRLS"
     gene            complement(4234..8103)
                     /gene="yvnB"
                     /locus_tag="CE047_RS05975"
     CDS             complement(4234..8103)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yvnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391384.1"
                     /locus_tag="CE047_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_038829908.1"
                     /transl_table=11
                     /translation="MRKYTVIASILLSFLSVLSGGHHESKAFPVVQQELFQTPHYIPLL
                     ENPPQIDVKAEMRSNLMIEAQVRDNSYQAFSAFLFYKQSNELGYKMVPMDPTPGAVRKF
                     LAQIPKRLIWNSELEYYIVMSNGKQRVESEMKKLKLEGYQADLAHIPELLITELAVDTK
                     NIGRADGYEFIEIFNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPDERILIPSGETFVV
                     WLKPAGHPELTSEDFNRYYQTQLKEGKNLAVIDETEGMANTRPRAVVISTNTGKDISVA
                     HYRKHALRRLSSVLYKYPLNGTAELLNISIGEKNPSPGTVLQAQVPEQKRKIKLDKEKP
                     VIEDLTDRKPVRPAESIELRADIRDRSLVKTAAFYYRTDENKPFKRILAEKDRNDNLYH
                     YIVYSPELIGKDQLEYYVAAGDGINEARTPVKMIDIKQTSKSHGLRMNIENRDTLSGTQ
                     FLKATTEGRADRIKLWIDGKKQVTEPAMEKEVYFAFDTRKTNLYFKNAVTMEGKVLKVF
                     DDTTNKYRTYSVPLPETLLRKGKQLQRITIRSGSKVSPFDTAENRDDFLVKNARLVLSD
                     GTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLEWDTSKLSEGAHHIQA
                     SDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSKIEEAEASLDGESI
                     TLPYHTSSSDLLPGKHSLKVTATDLAGNKTVIERIFKTEREHPDQPEVIDSEADTHKAK
                     LSVRVKDPTNDAMDVGFYRGFQYTARNHVKIFKHASLTEPPKSFVPESETPFTNKELER
                     VSAADGKTVSTENKELFPYHRFEVTVDPSIDENDLAEAVWKGSSLPGRKVTMYAWNYRT
                     NDWQPVDSFVAKDDKPFTLKASVIAADFVRESKMNVIVQDEIPPAKDMYTFVWMSDTQY
                     YAESYPHIFDKQTEWIKDNQKQLNIKYVFHTGDIVDDSADIRQWKNADRSMSVLDKSGI
                     PYGVLAGNHDVGHKDGSYRAFGKYFGSDRFDKKLHYGGSYKNNRGHYDLISSNGNDYIM
                     LYMGWGITNEDIAWMNQVLKKHPDRMAILAFHEYLLVSGNRSPIGEKIFKEIVKPNPNV
                     VMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQGGPEGGQGYLRLLQFDQANDM
                     VHVSTYSPYVKDKNYYDTDTYGNKDEFSLSLDLKPRIKKVETDYFECNVYTNEELGKRE
                     QVKSGDTAEFRWDHLEPQSVYYWYIIVEDSFNGKTKSPIWKFKTKKETYRPAPDQFDFR
                     HVSNP"
     gene            8268..8729
                     /gene="pchA"
                     /locus_tag="CE047_RS05980"
     CDS             8268..8729
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pchA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391385.1"
                     /locus_tag="CE047_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_021480697.1"
                     /transl_table=11
                     /translation="MNNSIHDELFQAIQQFALKRDKRVWQKVQIPSSQHLDHLKKDWTL
                     TQLHIVSCLHTSKNVNNSFLASRLHISKAAVSKAIQALLKHNIITVTKKPGNKKEIFYT
                     LTESGKELAGLHERLHQKAKEQYKQLFNEFSIDELKTVTAFINLWIKHM"
     gene            complement(8768..9985)
                     /gene="cypX"
                     /locus_tag="CE047_RS05985"
     CDS             complement(8768..9985)
                     /EC_number="1.14.15.13"
                     /codon_start=1
                     /gene="cypX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391386.1"
                     /locus_tag="CE047_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pulcherriminic acid synthase"
                     /protein_id="WP_038829907.1"
                     /sec_met_domain="p450 (E-value: 6.6e-37, bitscore: 123.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSIKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISR
                     YHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFIGDALDHL
                     SPLIKQNAENLLAPYLERGKIDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVAD
                     FITSISQSPEARAHSLWCSEQLSQYLMPVIEERRVNPGSDLISILCTSEYEGMAMSDKD
                     ILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPPVQ
                     LIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHREDLGIKSAFSGA
                     ARHLAFGSGIHNCVGAAFAKTEIEIVANIVLDKMRNIRLEEDFCYAEFGLYTRGPVSLH
                     IVFDRA"
     gene            complement(10001..10747)
                     /gene="pchC"
                     /locus_tag="CE047_RS05990"
     CDS             complement(10001..10747)
                     /EC_number="2.3.2.22"
                     /codon_start=1
                     /gene="pchC"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391387.1"
                     /locus_tag="CE047_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclo(L-leucyl-L-leucyl) synthase"
                     /protein_id="WP_163135875.1"
                     /sec_met_domain="CDPS (E-value: 2.2e-84, bitscore: 278.3,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGMVTERRSVHFIAEPLTENCREIFERRRHVLVGISPFNSRFSE
                     DYIHRLIGWAKAQFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERAL
                     VAHGGDPKAIHTFSDFMDNKAYQLLRQEVEHAFFEQPHFRHACLDMSREAIIGRARGVS
                     LMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHEFSIC
                     MRPNQGYLIVQEMAQMLSEKRITCEG"
     misc_feature    10873..10888
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    10875..10889
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.98"
                     /tool="antismash"
     misc_feature    complement(10876..10891)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.77"
                     /tool="antismash"
     gene            11173..11682
                     /gene="pchR"
                     /locus_tag="CE047_RS05995"
     CDS             11173..11682
                     /codon_start=1
                     /gene="pchR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391388.1"
                     /locus_tag="CE047_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pulcherriminic acid biosynthesis transcriptional
                     regulator PchR"
                     /protein_id="WP_163135876.1"
                     /transl_table=11
                     /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEVAEEDVAEIPK
                     NMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVY
                     FKLTRKGRRIFNLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQTDGT
                     PDKPVK"
     gene            11703..12914
                     /gene="pchE"
                     /locus_tag="CE047_RS06000"
     CDS             11703..12914
                     /codon_start=1
                     /gene="pchE"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391389.1"
                     /locus_tag="CE047_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_003228068.1"
                     /transl_table=11
                     /translation="MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTA
                     MVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLITGILATAAASIGCAVTTDFTLFLIF
                     RMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGAAGY
                     EGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSF
                     VLFFIYFAVIVYLPILLTEHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLF
                     IGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAI
                     GMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQK
                     KHHM"
     gene            complement(12942..13301)
                     /gene="yvlD"
                     /locus_tag="CE047_RS06005"
     CDS             complement(12942..13301)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yvlD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391390.1"
                     /locus_tag="CE047_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phage holin family protein"
                     /protein_id="WP_003228066.1"
                     /transl_table=11
                     /translation="MVKWAVSILVNALLLIVIDGYIDSIHISSIGAAIIASLILSILNV
                     LIKPLLIIFTLPVTMVTLGLFLFVINAITLMMTASIMGDSFQIDGFGTAIWASVILSVF
                     HLLIQKGILEPLRKK"
     gene            complement(13303..13500)
                     /gene="yvlC"
                     /locus_tag="CE047_RS06010"
     CDS             complement(13303..13500)
                     /codon_start=1
                     /gene="yvlC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391391.1"
                     /locus_tag="CE047_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PspC domain-containing protein"
                     /protein_id="WP_003228065.1"
                     /transl_table=11
                     /translation="MNKLYRSEKNKKIAGVIGGLAEYFNWDASLLRVITVILAIMTSVL
                     PVLLIYIIWIFIVPSERDMK"
     gene            complement(13505..14602)
                     /gene="yvlB"
                     /locus_tag="CE047_RS06015"
     CDS             complement(13505..14602)
                     /codon_start=1
                     /gene="yvlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391392.1"
                     /locus_tag="CE047_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4097 domain-containing protein"
                     /protein_id="WP_014478112.1"
                     /transl_table=11
                     /translation="MKQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALSV
                     HVHDEEEPFTTAKKESGKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQFKD
                     TDFSSVELQIANGSVNIVPWEDDDIRAECQAKVYRADSQDAARHAFLQHIECEIKGNKF
                     FIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSFSHLT
                     AEKAIAETANGQIKLASHSCGTIEAETINGLIDLRGKSESIDVQSFNGNIAINVTESDC
                     RSIYAKTTTGSVELAIPDDLAVKAELKSNLGSLSHELMDVEMLKEKNDTIQKEMMFTSN
                     QAHDQNITVFSESLTGAIKLKYSQR"
     gene            complement(14627..14953)
                     /gene="yvlA"
                     /locus_tag="CE047_RS06020"
     CDS             complement(14627..14953)
                     /codon_start=1
                     /gene="yvlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391393.1"
                     /locus_tag="CE047_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein YvlA"
                     /protein_id="WP_032726939.1"
                     /transl_table=11
                     /translation="MNRNQAIIASLCYFSVFIAPIIVPIVAYFVVNEKETKRHAIRSLI
                     SHIVPFVGWLFLFIALLGGAVAIDGDSLLPVFVIIGGAVIYFLVVIGIIIWNVIQGIKV
                     LREA"
     gene            15171..15401
                     /locus_tag="CE047_RS06025"
     CDS             15171..15401
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391394.1"
                     /locus_tag="CE047_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003235419.1"
                     /transl_table=11
                     /translation="MEKDPSDYTVTQESVLKLIHEQKRMNREMIAELEQIHGPFPISHD
                     IQYIKVLLDSSNTHIVQDLMSVSKQLYKKTL"
     misc_feature    complement(15187..15202)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(15600..16421)
                     /gene="hag"
                     /locus_tag="CE047_RS06030"
     CDS             complement(15600..16421)
                     /codon_start=1
                     /gene="hag"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391416.1"
                     /locus_tag="CE047_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flagellin Hag"
                     /protein_id="WP_029318328.1"
                     /transl_table=11
                     /translation="MRINHNIAALNTLNRLSSNNSASSKNMEKLSSGLRINRAGDDAAG
                     LAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHAILQRMRELTVQAGNTGTQQ
                     TEDLTAIKDEMDALTEEIDGISQRTEFNGKKLLDGSETAGFTFQIGANAGQNINVTIGN
                     MDATTLGVKGIDVSADDFSFDTEIVKIDSAITSVSNQRAKLGAVQNRLEHTINNLGASS
                     ENLTAAESRIRDVDMAKEMSDFTKNNILSQASQAMLAQANQQPQNVLQLLR"
     gene            complement(16759..19632)
                     /gene="uvrA"
                     /locus_tag="CE047_RS06035"
     CDS             complement(16759..19632)
                     /EC_number="3.1.25.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391396.1"
                     /locus_tag="CE047_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_003228057.1"
                     /transl_table=11
                     /translation="MAMDRIEVKGARAHNLKNIDVTIPRDQLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMDKPDVDAIEGLSPAISIDQKTTSRNPRSTVGTVT
                     EIYDYLRLLYARVGKPHCPEHGIEITSQTIEQMVDRILEYPERTKLQVLAPIVSGRKGA
                     HVKVLEQIRKQGYVRVRIDGEMAELSDDIELEKNKKHSIEVVIDRIVVKEGVAARLSDS
                     LETALRLGEGRVMIDVIGEEELMFSEHHACPHCGFSIGELEPRLFSFNSPFGACPTCDG
                     LGMKLEVDADLVIPNQDLSLKENAVAPWTPISSQYYPQLLEAVCTHYGIDMDVPVKDLP
                     KHQLDKVLYGSGDDLIYFRYENDFGQIREGEIQFEGVLRNIERRYKETGSDFIREQMEQ
                     YMSQKSCPTCKGYRLKKEALAVLIDGRHIGKITELSVADALAFFKDLTLSEKDMQIANL
                     ILREIVERLSFLDKVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSRLSGVLYILDEPSI
                     GLHQRDNDRLISALKNMRDLGNTLIVVEHDEDTMMAADYLIDIGPGAGIHGGQVISAGT
                     PEEVMEDPNSLTGSYLSGKKFIPLPPERRKPDGRYIEIKGASENNLKKVNAKFPLGTFT
                     AVTGVSGSGKSTLVNEILHKALAQKLHKAKAKPGSHKEIKGLDHLDKVIDIDQAPIGRT
                     PRSNPATYTGVFDDIRDVFAQTNEAKVRGYKKGRFSFNVKGGRCEACRGDGIIKIEMHF
                     LPDVYVPCEVCHGKRYNRETLEVTYKGKSISDVLDMTVEDALSFFENIPKIKRKLQTLY
                     DVGLGYITLGQPATTLSGGEAQRVKLASELHKRSTGRTLYILDEPTTGLHVDDIARLLV
                     VLQRLVDNGDTVLVIEHNLDIIKTADYIVDLGPEGGAGGGTIVASGTPEEITEVEESYT
                     GRYLKPVIERDKTRMKSLLKAKETATS"
ORIGIN
        1 aagttccccc agcggccgat cgcctggccg agcaaaatgc tgggcgcggc aatgtccgca
       61 agcttccaga acgaaagttt tttcactctc gaaaacacat aacccgttaa aatggcgccg
      121 attaatccgc catgaatggc aatgccgccc ttccaaatct taatgatttc tcccggatgt
      181 gccgcataat agtcccattc aaaggcaacg taataaattc gcgcgcaaat aatcgcaatc
      241 ggaatggcaa acaggacaag atcaataaac gtatctttct gcagcccccg tttttcactt
      301 tccctcatcg caatccacag cccgagcaaa gcgccgagac cgataatgat tccgtaccaa
      361 tggacggcta acggccccag ctgaaatgct atcggattga gtggttctat cgcttcattc
      421 atttaacgcc aactcctatt cttcttgttc accgtcttca atgacgtccg ccagcttgtt
      481 ggtgaattgt tcagcggcat tcagccccat ccgcttcaat ctgaagttca ttgctgccac
      541 ttcgatgatg actgcaagat ttcggcctgg acggacggga atcgtcagtt ttgtaatttc
      601 tgtatcaatg attttcatgg tctcttcctc aagtccgagc cggtcgtatt gcttgccctg
      661 ctcccagagt tcaagattca tgacaatcgt gattcgttta ttgcttctga ccgcgccagc
      721 gccaaatagc gtcatcacgt tgataatgcc aaggcccctg atctcaagaa ggtgctcaat
      781 taattccgga gcgtttccca caagagtatc ctgatcctcc tgccgtattt caacgcaatc
      841 atcggcaaca aggcgatgcc ctcttttcac aagctccagc gctgtttcgc tttttccgac
      901 gccgctcttt cctgtgatca gcacgccgac accatatata tcgacaagaa caccatgaat
      961 tgctgtggta ggcgccagcc tgctctcaag gaagttggtt aaacggcttg acagtcttgt
     1021 cgttttcagc ggcgatctga ggacaggcac cccatttttc tcggaggcgt caatcagctc
     1081 ctgcgggatg ggcatatctc tagaaagaat aatagctggt gttacatcag tgcacagaga
     1141 atccattcgc tgttttttct cctcttcagg aagctgttca aagaaagaaa gctctgtttt
     1201 tccgagaagc tgcacgcgct ctctcgggta atatgtaaaa tatccggcaa tttcaatgcc
     1261 tggtcttgat aggtcactca ttgtaatcgg gcggttaatt ccttcttctc cgctgattaa
     1321 ttccaaattg aactgttcca ttacgtcttt tgtgcgaacc tttgccacga tatgttcctc
     1381 ctgttccggg ctgccccgag cttgctcaca atactttcat tttatcactt tcaggcttga
     1441 acctaaaaca gattttataa aaggcgggaa aacacctcag ctggtctaga tcactagtct
     1501 gaaaaagagt aaaataaagg tattcaaatt ccagaaaggc ggatcatcta tggcagagag
     1561 tcttcttatc aaagacattg cgatcgtgac agaaaatgaa gtaatcaaaa acggctatgt
     1621 cggaatcaat gacggaaaaa tcagcacagt ctcaacagaa cggcccaagg agtcatattc
     1681 aaaagaaatt caagcacctg cgaattccgt tttgcttccc ggcatgattg acattcatat
     1741 ccacggcggc tatggcgcag atacgatgga tgcaagcttt tctgcgctcg acatcatgtc
     1801 gtcaagactt cccgaagaag gcacgacgag ctttttagcc acaacgatta ctcaggaaca
     1861 tgggaacatt tctcaagctt tggtgaacgc aagagagtgg aaagcggctg aagagtcctc
     1921 tttattaggt gcagaactgc tcggcattca tttagagggc ccctttgttt cacctaaaag
     1981 agccggagcg caaccaaaag agtggattag gccttcggat gttgcgcttt tcaaaaagtg
     2041 gcagcaggag gcgggcggac tgatcaaaat tgttacactt gcgccggagg aggatcagca
     2101 ttttgaactg atccgccatt tgaaagacga atcgattatc gcgtccatgg ggcacacgga
     2161 tgccgattcc gcaatgctgt cggatgccgc aaaagcaggg gcgagccata tgacccatct
     2221 gtacaacgcg atgagcccgt ttcatcaccg agaacccgga gtgatcggaa cggcgctggc
     2281 ccatgatggg tttgtgacag agctaatagc cgatggcatc cactcccatc ctttagcggc
     2341 taagcttgct tttttggcga aaggcagcag caagctcatt ttaattaccg attccatgag
     2401 ggcaaaagga ctgaaagacg gcgtttatga gttcggcggc caaagtgtga cggtaagagg
     2461 acgaacagct cttctttcag acggaaccct tgccggttcg atcctcaaaa tgaacgaagg
     2521 tgcacggcat atgcgtgagt ttacaaattg ctcttggacg gatatagcta atataacttc
     2581 tgcaaacgcg gccaaacagc tgggcatctt tgaccgaaaa ggcagtgtga ctgtgggaaa
     2641 agatgcagat ttagtgattg tcagcagtga ttgcgaggtg attctcacca tttgccgcgg
     2701 aaacattgca tttatatcca aggaggctga ccagatatga aagtaatgga atgtcaaacg
     2761 tatgaagagc taagccaaaa agcagccaga ataacggcag atacaatcaa ggaaaaacct
     2821 gatgccgttc tcgggttagc gacaggcggc acaccggaag gcacttatcg cgagctgatc
     2881 cgcctgcacc aaactgagaa tctctcattt caaaacgtca ctacagttaa tttggatgag
     2941 tacgccggac tttcaagcga tgacccgaac agctatcact tctatatgaa cgaccgtttt
     3001 tttcagcata tcgacagcaa gcctagccgg cattttattc cgaatggaaa tgcagacgat
     3061 ttggaagctg aatgcagacg gtatgaacag ctagtcgagt ccctcggcgg cactgacatt
     3121 cagcttctcg gcatcggccg aaacggacac atcggcttta acgaaccggg aacgtctttc
     3181 aagtcgcgaa ctcatgttgt gacattaaat gagcaaaccc gccaagcgaa tgccagatat
     3241 tttccctcca tagacagcgt gccgaaaaaa gcactgacaa tgggaattca aacgatactc
     3301 tcaagcaagc gcattctgct gcttatttct ggaaaaagca aagcggaagc tgttcgtaag
     3361 ctgttagaag gaaacataag cgaagatttt cccgcatctg ctttgcacct gcattccgat
     3421 gttacggttt tgattgatcg tgaagccgcg tcattaagac cttgaaagga acatgctgac
     3481 ttatgaatat caataaacaa tcgcctattc cgatttacta tcagattatg gagcaattaa
     3541 aaacccaaat taagaacgga gagctgcagc cggatatgcc tcttccttct gagcgcgaat
     3601 atgccgaaca attcgggatc agccggatga cagttcgcca ggcgctttct aatttagtta
     3661 atgaaggctt gctctatcgc ctgaaagggc ggggcacctt tgtcagcaag ccaaaaatgg
     3721 aacaagcact tcaagggctg acaagcttta ctgaggatat gaaaagccgc gggatgacac
     3781 cgggcagcag gctcattgat tatcagctta ttgattcaac tgaggagctc gcggctatat
     3841 taggctgcgg gcacccctcc tctatccata aaatcactcg ggtgcggctg gcaaatgata
     3901 ttccgatggc gattgagtcc tcacatattc cctttgagct tgcgggtgaa ttaaacgaat
     3961 cgcattttca gtcgtcgatc tatgatcata ttgaaaggta caacagcata ccgatttccc
     4021 gtgcaaaaca ggagcttgag ccaagcgctg ccaccacgga agaagcgaat attcttggta
     4081 ttcaaaaggg agcgcctgtc ctattaatta aacgaacgac atatctgcag aacggaactg
     4141 cttttgagca tgcaaaatcc gtatacagag gcgaccgtta tacatttgtc cactatatgg
     4201 atcgtctttc ataaaaaaag cctccaaccc tttttaagga ttggagacat ggcgaaaatc
     4261 aaactggtct ggtgccggac gatatgtttc ttttttcgtc ttgaacttcc agatcggtga
     4321 tttcgttttg ccgttaaaac tgtcttccac tataatgtac caataataaa cagactgcgg
     4381 ttcaagatga tcccagcgga attcagctgt atccccgctc ttcacttgct cccgttttcc
     4441 aagctcttca ttggtatata cgttacattc aaaataatcg gtttccacct ttttgattct
     4501 tggcttcaaa tcaagcgaaa gggaaaattc atccttgttg ccataggtat ccgtatcata
     4561 gtaattctta tcctttacat acggagagta tgtcgatacg tgtaccatgt cattggcctg
     4621 gtcaaattga agcaaacgca aatatccttg cccgccttct ggcccgccct gataatcggc
     4681 cagcatttga tgcacaagac gatccggctt cccatcacca tcatcatcca gctcatctgt
     4741 ttttctcatc gcactatgat aatgcccgct caataccatc acgacattcg ggttcggctt
     4801 tacgatttct ttgaatattt tctctccgat cgggcttctg tttccgctga ccagcaaata
     4861 ctcatgaaaa gctaaaatgg ccatccggtc agggtgtttc ttcagcacct gattcatcca
     4921 cgcgatgtct tcattcgtaa tgccccatcc catgtacagc atgatataat cattgccgtt
     4981 gctagaaatc aggtcataat gtccgcggtt gtttttatag gaaccgccat aatgcaattt
     5041 tttatcaaaa cgatcgctgc caaaatattt gccaaacgcc ctgtaggagc cgtccttatg
     5101 cccgacatcg tggttgccgg ccagcacgcc gtaaggtatt ccgctcttat ccagaacgga
     5161 cattgaccga tcagcgtttt tccactgtct gatatcggca gaatcatcta caatatcacc
     5221 cgtgtggaac acatatttga tattgagctg cttttgatta tcttttatcc attcggtctg
     5281 tttatcaaaa atatgcggat agctttcggc gtaatactgt gtatcagaca tccagacaaa
     5341 tgtgtacata tccttcgcag ggggaatttc atcctgtaca atcacattca ttttcgactc
     5401 ccgtacaaaa tcggcggcaa tcacagacgc tttcagcgta aacggtttgt catccttcgc
     5461 gacgaagctg tcaacaggct gccaatcgtt tgtccgataa ttccaagcat acatcgtcac
     5521 ctttctcccc ggcaaagaac tgcccttcca gactgcttct gccagatcat tctcatcaat
     5581 tgatggatca accgtcactt caaagcgatg ataagggaaa agctctttgt tttctgtcga
     5641 tactgttttt ccatcagcag ctgatacccg ctccaattct ttattcgtaa atggggtctc
     5701 actttccggc acaaagcttt tcggcggttc agtcagtgac gcgtgcttaa atattttcac
     5761 atgatttcgc gctgtatatt gaaatcccct ataaaaacca acatccatgg catcattcgt
     5821 cggatctttc acccgtacag aaagcttggc cttatgcgtg tcggcttcgc tgtctataac
     5881 ctccggctgg tccggatgct ctcgttcggt tttaaatatc ctctcaatca ctgttttatt
     5941 gcccgcgaga tccgttgctg tcacttttag agaatgtttt cccggcaaaa gatcagaaga
     6001 ggacgtatga tatgggagtg taatgctttc tccatctaaa gacgcttccg cttcctcaat
     6061 tttgctccat ttatcataca tatccgcctg caggataagg tttcctttat acgtttgccc
     6121 ctcggtgata ttcggctcaa tgtgaggtcc tgaattatct acccgtacaa ccaggctgac
     6181 attttccttg ccgtcgcttg cttgaatatg gtgagcgcct tcagaaagct ttgatgtgtc
     6241 ccactccagc agctgtgatg taaacagtcc gtcaggcaga ttgaactgaa attgccagct
     6301 tttattcgag cgctgattat cgccaataaa gagttccttc tcaggggaca ccctctgatc
     6361 cctgatcacc gttccatccg ataacaccaa tcgggcgttt ttgactaaga agtcatcacg
     6421 gttttcagcc gtatcaaacg gagacacctt cgaacccgat cgtattgtaa tacgctgcag
     6481 ctgcttccct ttccgaagca gtgtctctgg caatggaaca gaataggtgc ggtatttatt
     6541 tgttgtatca tcgaacacct tcagcacttt gccttccatc gttaccgcgt ttttaaaata
     6601 aaggttcgtt ttcctcgtat cgaatgcaaa atatacttct ttttccatcg cgggctctgt
     6661 cacttgtttt ttcccgtcaa tccatagctt aatgcggtca gctcgccctt ctgtcgtggc
     6721 tttgagaaat tgagttcccg acagcgtgtc tctgttttca atattcatcc gcagaccgtg
     6781 cgacttgctt gtttgtttaa tatcaatcat tttgaccggc gttctcgctt cattgatccc
     6841 gtccccggcc gccacataat actctagctg atccttcccg atcaattcag gcgaatacac
     6901 aatataatgg tagagattat cgttgcggtc tttttcagca agaattcgct taaacggttt
     6961 gttctcatcc gtccggtagt aaaaggccgc tgttttcact agacttcggt cccgtatgtc
     7021 agcccgcagc tcaatgcttt cagcagggcg gacaggcttg cggtcagtca aatcctcaat
     7081 gaccggcttt tctttatcga gcttgatttt tcgtttctgc tcgggcacct gtgcctgtaa
     7141 tacggttccg ggagatggat tcttttcccc gattgaaatg ttcagaagtt ctgcggttcc
     7201 gttcaacgga tacttataaa gcactgatga cagccggcgc agcgcatgtt tccgataatg
     7261 cgcaaccgaa atgtcctttc ctgtattcgt tgatatcaca acggcccgcg gcctcgtatt
     7321 ggccataccc tctgtctcgt ctatcaccgc gagatttttt ccttctttaa gttgtgtctg
     7381 ataataacga ttgaaatcct ctgacgtcaa ttctggatgc ccggcaggct tcagccagac
     7441 gacaaacgtt tcgccggatg gtatcaagat cctttcatca ggtctccaaa tcagatcgga
     7501 gtcaggccct tcttttgggt agcggtaacg gatatggtag tctttaaaat caatcgttct
     7561 gtcagtcgta ttaaaaatct caataaattc ataaccgtct gcacgtccta tattcttcgt
     7621 atcaaccgcc agctctgtga tcagaagctc cggaatatgg gcaaggtcag cctggtatcc
     7681 ttcaagcttc agtttcttca tctccgactc cacccgctgc ttcccattcg acatcacaat
     7741 gtaatactca agctcgctgt tccaaatcaa acgtttcgga atttgtgcca aaaacttgcg
     7801 gaccgctccg ggggtcgggt ccatcggcac cattttgtag cccagctcat tactttgttt
     7861 ataaaaaaga aaggcggaaa atgcttgata cgaattatcg cgaacttgag cctcaatcat
     7921 tagattgctt ctcatttcag ctttcacatc aatttgagga ggattttcaa gcaagggtat
     7981 gtaatgaggc gtttgaaata gttcctgctg tacaacagga aaagctttcg attcatgatg
     8041 gccgccagac aaaacggaaa gaaaagacag taatatagaa gcaataaccg tgtatttcct
     8101 catcaaagca cctccctttt catgtatttt gcgtctgaac agggaagctt atgagttcat
     8161 ttttgtgcat aaagaacaaa aaaacgtctg cctcttgaaa attccactat tccccagtaa
     8221 actaaggata gttaaccagt taacaattaa atcagagagg caaattgatg aacaacagca
     8281 ttcatgatga attatttcaa gctatacaac aattcgcatt aaaaagagat aaacgcgtct
     8341 ggcaaaaggt gcagattccg tcctcacaac atctcgacca cctcaaaaaa gactggacat
     8401 tgacccagct tcacattgtt tcctgtttac ataccagcaa aaatgtgaat aacagcttct
     8461 tagcatcccg cttacatatc tcaaaagcag ctgtttcaaa agcaattcaa gctctgttga
     8521 aacataacat cattacagtg acaaaaaagc cgggcaacaa aaaagaaatt ttttatacgt
     8581 taactgaaag cggcaaagaa ctggcggggt tacatgaacg gcttcatcaa aaagcaaagg
     8641 agcaatacaa acagctcttc aatgaatttt caattgatga gttgaaaaca gtgactgcgt
     8701 ttattaactt gtggatcaag catatgtaaa aaagcctcac ccgcacggga gagacctttc
     8761 catattatta agccctgtca aatacaatat gaagtgagac gggtccgcgt gtatacagac
     8821 cgaactcagc ataacaaaaa tcttcctcta atctgatatt ccgcatctta tccagcacaa
     8881 tattagctac aatttcgatt tcggttttgg caaaagctgc tcctacacag ttatgaatgc
     8941 cggatccgaa agcgagatgc cgggcggcgc cgctaaaagc gctcttgatg ccaagatctt
     9001 cccgatgaat attaaacacg tcaggctgtt caaatgcttc agggtcccgg ttagccgcac
     9061 cgatcataca aaaaacaatc gtatcttttt tgatttccat accgccgacc actgtatctt
     9121 gggacagctg ccgcggaatc agctgaaccg gcggtttata acgcaatgtc tccgcaatgg
     9181 ctctcggaac taacgaacgg tcagccaaaa catcattcat ctgctcagga ttgttgagca
     9241 aatggtagat catcagtgcc agcgtcttat cagccggttc cgttgcggct aacagcacat
     9301 taagaatcag tgcgagtata tccttgtccg acatcgccat gccttcatat tcagaagtac
     9361 ataggatgga aattaaatct gatcccggat tgacgcgacg ttcttcaatg accggcatca
     9421 agtattggga aagctgttcg ctgcaccata acgaatgtgc ccgcgcttca ggagattgag
     9481 agatactcgt gataaaatcg gcaactccgc tgtgccactc agagattttt tcatggtctc
     9541 ttttatccag cccgagcatg tccatcgtga cgcacaccgc aaacgtcttt ccaaaatcat
     9601 tgacgagatc aattttccct ctttcaagat aaggcgctaa caagttttct gcattttgtt
     9661 taatcaatgg agacagatga tccagtgcgt caccgatgaa gcttctcact acaattcttc
     9721 ttttggcaga gtgttctttt ccatgcattt gggccagcac agggcctcgc attactggtt
     9781 cggcacgctc aacaagtgat ttcgtcgtga aaatatccgg atgctgaagg atatagcgga
     9841 catcatgata gcggctgata aaataactgt ctatcgactc ttcataatga accggatctt
     9901 cctcccgcag ttgtgaaaaa taagcatatg gattgttttg aaattgatca gaaagcacac
     9961 taaacaattt aatcgattgg ctcatgtttt actcccccta tcatccttca catgtgatcc
    10021 gtttctcaga aagcatctgc gccatttcct gtacaatgag atacccttga ttcggccgca
    10081 tacaaataga aaattcatgg ttactgatct tctcaccgag cttccacgga cgatgataag
    10141 caaggagcgt ctcttccacc tctaaaatat ccggagctcc gataaaaaac ggcagctcag
    10201 ctatgacata ttccacagcc aaattcagca tatcctcact gacttcttcc atcatcaaac
    10261 tgacgccccg tgcacgcccg attatcgctt cacgagacat gtccaaacaa gcatgtcgaa
    10321 aatgaggctg ctcaaaaaaa gcatgttcaa cttcttgtct caacagctgg taggctttgt
    10381 tatccataaa atcagaaaat gtatgaatcg ccttcggatc cccgccatga gccacaagag
    10441 ctctttctgc aaatctcctg tttcgtgata cctctttcct tacttttcgt tcagcctttc
    10501 ctctcggagt tccaagcgct tctagaagat tagcggcctc atgccccgca agtaaaacag
    10561 aaacgctttt aaattgagct ttcgcccatc caattaatct gtgaatataa tcctctgaaa
    10621 acctgctgtt aaatgggctg atccccacca aaacatgcct gcgccgttca aatatttctc
    10681 tgcagttttc cgttaatggc tcagcaataa aatgcacaga ccttctttcc gttaccattc
    10741 cggtcatctc attcacccct aaaacttatc ccgctttaag tcatcaccct caaatacaag
    10801 atggaatagc tagaacaact gaacaagacg aatggcaggc atcacttaaa gtttccaaat
    10861 gttttttaag attttaataa tcattttcaa tacccatatc atgataaatg tttactagta
    10921 aacattagtc attttatccc ttttccttcc aaacgtcaat atgatctgtg cccaaatatt
    10981 tgaaaataaa tgtaaacatc acattttcca cacacttttt acacgcatat tcagcatgac
    11041 atatcaacaa atagtctaaa caccaacaat tgacaacgaa aacaagaaaa gataaaataa
    11101 aattgttcac cagtaaacga tttgttttat tgtttcatcg taaactatta ttcctaagaa
    11161 agaaggtagc ctatgtctga tttgacaaaa cagatgatat acgacatata cgtgagactg
    11221 ctgcacctta atgaacaaaa agcgaacact tcacttcagc aattttttaa ggaggtcgca
    11281 gaagaggatg tagctgaaat tcccaaaaat atgacaagca ttcacgtcat tgactgcatc
    11341 ggccagcatg aacccattaa caatgcgggg attgccagaa aaatgaactt atcgaaagcg
    11401 aatgtaacga aaatcagcac aaaactgatc aaggaagaat tcattaacag ctatcagctg
    11461 acagataaca aaaaagaagt ttattttaaa ttaacccgta aaggcagacg gattttcaac
    11521 ttacatgaga aactgcataa aaaaaaggag ctggcttttt accaattcct cgattcattt
    11581 tcacaagaag aacaaaaggc tgtattgaag tttctagagc agttgacgtc aacacttgaa
    11641 gcagaacaaa ccgatgggac tccggacaaa cctgtaaagt aaacaaaaag gcggtgtaca
    11701 ctttggctca tacaaaatca aaggcagtat tgatcttata cactgtttgc ttcagtgcat
    11761 tttttgcatc tttaagccag aacatttatt cacctattct tcctatcatt aaagaatcat
    11821 tccatgtttc cacagctatg gtgaacctgt cagtctcagt ttttatgatt gtgacagcaa
    11881 taatgcaaat tatattagga gcgatcattg attttaaagg cgctcggatc gtcttgatta
    11941 ccggtattct ggcaacggca gcagccagca tcggctgtgc ggtgactact gactttactt
    12001 tgtttctgat attcagaatg atacaggcag ccggttccgc agcactgcct cttattgctg
    12061 ccacaacgat cggacagctg tttacaggca atgaacgcgg gagtgcaatg ggaacgtatc
    12121 aaatgctcct gtctgtcgca ccggctattg ccccagttct aggaggattc ataggcggag
    12181 cagccggata cgaagggatt ttttggatac ttgcggccat ctcgatcgtt ttgctggtga
    12241 caaacagcat cacctttcct aaagattctc caactgaatc tatgcagcaa gccaaaggca
    12301 atgtgttcgc tcattataaa tcaatattta caaatcgaac agggaacgtc attttgactt
    12361 taagttttgt tctctttttc atttattttg cagtaattgt ctacctccca atattgctga
    12421 cagagcatta ccatatagat gtgggtatag caggactgtt atatttgccg ctggcgctga
    12481 gcacgattgc aggtacgttt ctgtttaaaa gaatacaggc aaaaatcggg ctgcacacct
    12541 tgtttatcgg aagcaatgtg attgccgcct gcagcatcat tttatttgct gttacacatt
    12601 ccgtttctct cgttctcatg gctctgacgc tggcactgtt tggcatctcg atgggggtta
    12661 ttcctccctt gtactctaca atgattacta atgaatttga gcacaacaga gggagtgcaa
    12721 tcggaatgtt taactttatc cgatatacag gcatggcagc aggtccgatg gtatctgcct
    12781 acttgctcac aatgatgccg tctgccatgt cctttagcct cctaggcctt ggatttgccg
    12841 cattgagctt ttgccttctt ccgccaatgt tttcgccgca gaagcgcacg aaacaaaaaa
    12901 agcaccacat gtaaaaaagc tgcctttgcg ggcagctttt tttatttttt tctaagcggc
    12961 tctaaaatgc ctttttgaat cagcaaatgg aagaccgaca ggataacgga tgcccatatc
    13021 gctgtgccga agccgtcgat ttgaaagctg tcacccataa tggacgcggt catcataagc
    13081 gtgatggcgt taatcacaaa caagaagagc ccaagcgtca ccatagtgac cggcagtgta
    13141 aagataatta aaagaggttt aatcagcacg tttaagatcg ataaaatgag gctggcgata
    13201 atcgctgccc caatgctgct gatatggatg gagtcaatat atccatcaat gacgattaat
    13261 aacaatgcat tgactaaaat gctgactgcc cattttacca tgttatttca tatccctttc
    13321 tgacgggacg ataaaaatcc aaatgatata aatgagcaaa accggcaaga cacttgtcat
    13381 aatggctaag atgacagtta tgactctgag gagtgatgcg tcccaattga aatattccgc
    13441 gagacctccg ataacaccgg cgattttctt atttttttct gagcgataaa gcttattcat
    13501 tcgatcacct ctgtgagtac tttagtttga tggcgcctgt tagtgattct gagaagacgg
    13561 ttatgttttg atcatgtgct tgatttgaag tgaacatcat ttctttttga atggtatcat
    13621 ttttttcctt cagcatctca acatccatta attcatggga cagcgaacca agattgcttt
    13681 tcagctctgc cttcactgcg agatcgtccg gaatcgcaag ctccacactt ccagtcgttg
    13741 tttttgcata aatggagcgg cagtctgatt ctgttacgtt aatcgcaata tttccgttaa
    13801 agctttgaac gtcaatggat tcgcttttcc ctctgagatc gatcaatccg ttaatggttt
    13861 ccgcttctat cgttccgcag ctgtggctgg cgagcttaat ttgcccgttg gccgtttcag
    13921 ctatggcttt ttcggctgtt aagtgcgaga acgacagcac gccgtttgtc gttttcgctg
    13981 agaactcttt tacatgtaaa tgttcccctc tgaccggacc gttaaacagc ttcactcgaa
    14041 tcttatcata ctccttctga ggaatataca aagtgacatt cgttttcatc gtctttttct
    14101 cagtacggat aaaaaactta ttacctttga tttcacattc aatatgctga agaaatgcgt
    14161 gtctcgccgc atcctggctg tcagcgcgat ataccttcgc ctggcattcc gctctgatat
    14221 cgtcatcttc ccaagggacg atattcacgc tgccattggc aatttgcagc tcaacactgg
    14281 aaaaatcagt atctttaaat tgaaaaatgt gctgaacatc atacgcatgg ccaaagttta
    14341 aatcaaggtc aacttccttg acctttttta cagcagaatc aatccagtca aacagcttgg
    14401 ctcctaaaga cggcttgccg ctttcttttt ttgccgttgt aaatggctct tcctcgtcat
    14461 gaacgtgaac tgagagcgct gtgattttct cttctttttc cttgtagtcg ctgtcaagct
    14521 tttcaatcag tgtcaaagct tcttgtgctg taagctttcc ttcctcaaca agcttaagga
    14581 ttcgttcctt ttcttgcttc attacgatct cctccccatt gtctacttat gcttcacgta
    14641 ggaccttaat gccctgaatc acattccaaa taataatgcc aatgacaact aagaaataaa
    14701 taaccgctcc cccgatgatt acaaatacag gaagcaagct gtctccatca atcgcaacgg
    14761 ctccgccaag taaagcaata aaaaggaaca gccagccgac aaacggaact atgtgagaaa
    14821 taagagagcg tatcgcatgg cgttttgttt ctttctcatt tacaacaaaa taagcgacaa
    14881 tcggcacaat gattggcgca ataaacacac tgaaataaca aagtgatgca ataatagctt
    14941 gattacggtt caattcattc cacactccta ttgtgaattg tccatgacaa aagatcaggg
    15001 acgttttact tatttatacg tttaaaatct cttcaggttt caaattcatt ctttagacat
    15061 gctccgattt acggaaattg gattttaaaa agttttagaa gtagaatctt ccggctatac
    15121 cgattacaat atgtaaaaag cttacggcaa ccaaggaggc tggacaagca atggagaaag
    15181 atcccagtga ctatacagta acacaagaat cagtgttaaa gctgattcat gaacaaaaaa
    15241 gaatgaatcg tgaaatgatc gccgagcttg agcagattca cggacccttc ccgatctctc
    15301 acgatatcca atatataaaa gtgctgctcg acagcagcaa cacgcatatt gttcaagatt
    15361 taatgagtgt aagtaagcag ctgtataaga agactttgta attgcggaaa acatatcatt
    15421 cattataact gaaacaaagt taaaggttag atgacaatat cttgcctttt ttgttttgaa
    15481 aaaacaagtg attccctggc tgtcacaaaa tgattgtaac aaaaaaagcc tgccggcaca
    15541 tccagttaat ggactctgtc ggcaagctgt aactatcaga aagagatagc cgttcaaaat
    15601 taacgtaaca attgaagcac gttttgcggc tgttggtttg cttgggcaag catcgcttga
    15661 gaagcttgag aaagaatgtt gttctttgtg aaatcgctca tttctttcgc catgtcaacg
    15721 tcacggatgc gagactcagc agctgttaag ttttcagaag aagcaccaag gttgttgatt
    15781 gtgtgctcta gacggttttg taccgcacca agtttagcac gttggtttga aacacttgta
    15841 attgcactat cgattttaac aatctcagtg tcaaaactaa aatcatctgc tgaaacatcg
    15901 atacctttta ctcctaaagt tgttgcatcc atgttaccaa ttgtaacatt aatattttgg
    15961 ccagcatttg caccaatttg gaatgtaaat cctgctgttt cactaccgtc taaaagtttt
    16021 tttccgttaa attcagtacg ttgagaaatt ccatcgatct cttcagttaa agcatccatt
    16081 tcatctttaa ttgcagttaa atcttcagtt tgctgtgtac ctgtgtttcc tgcttgaaca
    16141 gtaagttcac gcatacgttg aaggatggca tgagtttcag tcaatgcacc ctcagctgtt
    16201 tggataagag aaattccgtc ttgagagttt ttagaagcca tttcaagacc tctgatttgt
    16261 cctctcattt tttcagaaat cgcaagaccc gctgcgtcat ctcccgcacg gttgatgcga
    16321 agaccagaag aaagtttctc catgtttttt gagctcgcac tgttgtttga agacaaacgg
    16381 tttagtgtgt taagcgctgc aatattgtgg ttgattctca tgtgaaaaat acctccatgt
    16441 gtatatgttt ttgaaatcaa agacttcctt ttctttgatt tctggcgtat cagattccaa
    16501 taaagcttct aacctatgta gattcagtta ttgcttaagg atgcctttaa gccctttaat
    16561 agggtttgtc tgcttaattt ggaaatcatc atccgccttt caattcatat atcgacagca
    16621 atttgtaaat gtttaggcgt tttcccaaag aaattttacc aaagacgaat ctaaacctat
    16681 tatgccgtaa agaaaaagct tgcctgctaa gcccaaggat ggacttgctg acaagctgtc
    16741 ccctcttaac agagggtttt aagatgtagc tgtttctttc gctttcaaga gcgatttcat
    16801 gcgtgttttg tcacgttcga taacaggctt caaataacgg cctgtatacg attcttccac
    16861 ttcagtgatt tcctcaggcg ttcctgacgc gacaatggtt ccgcccccgg ctccgccttc
    16921 cgggcccaaa tccacaatgt aatcggccgt cttaatgata tcaagattgt gctcaataac
    16981 cagtacagtg tctccgttgt ctaccaaccg ttgcagcacg acaagaagcc tggcgatatc
    17041 gtcgacatgc aaacctgtcg tcggctcgtc taaaatgtag agcgtgcgtc cggtcgagcg
    17101 tttgtgcagc tcagatgcga gcttcacgcg ctgcgcttct ccgcctgaca aggtcgtcgc
    17161 cggctggccg agcgtgatat aacctaaacc aacatcataa agggtttgga gctttcgttt
    17221 gattttcggg atattttcaa agaaagaaag agcatcttca accgtcatat caagcacatc
    17281 agagatgctt tttcctttgt acgtcacttc aagcgtttca cggttatagc gtttgccgtg
    17341 acacacctcg catggaacgt atacgtcagg aaggaagtgc atttcaattt taataatccc
    17401 gtctccgcgg caggcttcac atcgtccgcc cttcacgttg aagctgaaac ggcctttttt
    17461 atagccgcgg accttcgctt catttgtctg cgcgaataca tcacgaatgt catcaaatac
    17521 accggtgtat gtcgcagggt tggatctcgg cgttcttccg attggcgcct ggtcaatgtc
    17581 aatgactttg tctaagtgat ccaaaccttt aatctcttta tggctgccgg gcttcgcttt
    17641 cgctttatga agcttttgcg ccagcgcctt atgcaaaatt tcattaacga gtgtactctt
    17701 tcctgaacca gaaacacctg taactgctgt aaacgtccca agcgggaact tggcattcac
    17761 ttttttcaag ttgttttctg aagcaccttt aatttcaatg taacgtccgt ccggctttct
    17821 tctttcagga ggcaatggga taaacttttt ccctgataaa tagctgcccg ttaatgagtt
    17881 tggatcttcc atcacttctt ccggcgtacc cgcagatatc acctgtccgc cgtgaatgcc
    17941 ggctcccggt ccaatgtcta ttaaataatc tgctgccatc atcgtgtcct catcatgttc
    18001 gacaacaatc agcgtgttcc cgaggtctct catatttttc agagcgctga tcaagcggtc
    18061 gttatcacgc tgatgcagac cgatagacgg ctcatctaaa atataaagca caccggataa
    18121 acgcgagcca atttgagtcg ccagcctgat gcgctgcgcc tctcctccgg acaatgtacc
    18181 cgctgccctg ctcaatgtca ggtaatcgag accgactttg tccagaaagc ttaagcgctc
    18241 cacaatttcg cgcaaaatca aattggcgat ctgcatatcc ttctcagaaa gggtaaggtc
    18301 tttaaagaag gcaagtgcgt cggcgacaga cagctcggta atttttccaa tgtggcggcc
    18361 gtcaatcagt acggcaagcg cctctttctt taaccgatag cctttgcacg tcggacaaga
    18421 cttctgagac atatactgct ccatttgctc acgtatgaaa tcggagcctg tctccttata
    18481 gcgtctttca atgttgcgca atacgccttc aaattgaatt tcaccttcgc gtatttgtcc
    18541 aaaatcattt tcatatcgga aataaatcag gtcatccccg ctgccgtaca gcactttatc
    18601 cagttgatgc ttcggcaaat ctttgaccgg cacatccata tcaatcccgt agtgggtgca
    18661 gactgcctca agcagctgag gataatattg tgagctgatc ggtgtccaag gggcgaccgc
    18721 attctccttc aatgacaaat cttgattggg gatgacaaga tcggcatcca cttcaagctt
    18781 cattccgaga ccgtcacacg tcggacacgc cccgaacgga ctgttaaacg aaaacagacg
    18841 cggctcaagc tcaccaattg aaaatccgca gtgcggacag gcatgatgct cgctgaacat
    18901 cagctcttcc tcaccgatga catcgatcat aacccgtcct tcccctaaac ggagcgccgt
    18961 ttccaatgaa tctgacagcc gggctgccac gccttctttc acgacaatcc ggtcaatgac
    19021 aacctcaatg gaatgcttct tgttcttttc taattcgata tcgtcggaaa gctcagccat
    19081 ctcgccgtca attctgactc tgacatagcc ttgttttcta atctgttcaa gcactttgac
    19141 atgagcgcct tttcggcccg agacaatcgg cgccagcacc tgaagcttcg tccgttccgg
    19201 gtattccaga attctgtcca ccatttgctc gatggtctgg gatgtaatct caattccgtg
    19261 ttccggacaa tgaggcttcc ctactctcgc atataaaaga cgcagataat cataaatctc
    19321 agttaccgta ccgacagtag acctcggatt gcggctcgtt gttttctgat caatgctgat
    19381 ggcgggagag agcccctcaa ttgcatccac atcaggctta tccatttgcc ctaaaaactg
    19441 gcgggcataa gcagacagcg actcgacata ccgtctctgt ccttcagcat atatcgtgtc
    19501 aaaggcaagg gaggatttac ctgatccgga caaacccgtg acaacgacaa gctgatctct
    19561 cggaatcgtt acatctatat ttttcaggtt atgcgccctg gctcccttca cctctatccg
    19621 atccatagcc atttgttcat catccttccg cttttagctc taaaagtaaa tcgcgaagct
    19681 ccgcggctct ttcaaagtca agcgccttgg cggcttcctt catttcatgc tccatctgtt
    19741 caacgacttt ctggcgttct ttcttcgtca ttttcgacag cttcggcgca gcttttgttt
    19801 tgtattccgc tttatcctca gctgctactg tggcacgaat gacatcgcga atttctttat
    19861 ttatcgtttt cggcgtaatg ccgtgctctt cattaaaccg ctcctgctgc tcgcgtcggc
    19921 gttttgtttc attaatcgca atttccatag acttcgttat tttatcggcg tacataatga
    19981 cgcggccttc cgcatttctc gctgcccgtc cgatggtctg gatcagcgac cgctccgaac
    20041 gaaggaaacc ttccttatcc gcatccaaaa tcgcaacaag ggatacttcg ggaatgtcca
    20101 aaccttccct cagcaggttg atgccgacaa gcacatcgta cttgccaagg cgcaggtcgc
    20161 ggataatttc aatccgttca agcgtcttga tttcagaatg cagatagttt actttaatgc
    20221 cgatttcctt taaataatcg gtcagatcct ctgacatctt cttcgtcaaa gttgtcacaa
    20281 gcacccgttc atttcgctcg attcttgctt gaatttcgcc gatcaagtcg tcaatctgac
    20341 cttcgattgg acggacgtca ataagcgggt caagaagccc cgtcggacga atgatctgtt
    20401 cgaccatttc atctgtatgt tcaatctcgt acggccctgg tgttgctgat acatacacga
    20461 tattgtgcat atgcttttca aattcctcaa aacgaagcgg acggttatca agcgctgatg
    20521 gaagccggaa gccgtgatcc acgagcacct gtttccgcgc ctggtctccg ttaaacatgc
    20581 cgcgcacctg gggaattgtc acatgcgact catccaccac gatcataaaa tcgtctggga
    20641 aataatcaag aagcgtatac ggcgttgaac ctggaggccg cagagtcaaa tgtcttgaat
    20701 agttctcgat gccggagcag aaacccattt cacgcatcat ttcaaga
//
