LOCUS       NZ_NJRD01000005        28791 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain 20-3 20-3_R1_(paired)_contig_5, whole
            genome shotgun sequence.
ACCESSION   NZ_NJRD01000005
VERSION     NZ_NJRD01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 626870)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 626870)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010578135.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:42:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,274
            CDSs (total)                      :: 4,198
            Genes (coding)                    :: 4,064
            CDSs (with protein)               :: 4,064
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1 (5S, 16S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (5S, 16S)
            tRNAs                             :: 67
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 80 of 134
            Pseudo Genes (incomplete)         :: 67 of 134
            Pseudo Genes (internal stop)      :: 22 of 134
            Pseudo Genes (multiple problems)  :: 31 of 134
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 28791
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NJRD01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28791
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..28791
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..28791
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[<0:8791](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <1..8791
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..26910
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4951:16910](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4952..16910
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     gene            <1..4944
                     /gene="ppsD"
                     /locus_tag="CE053_RS12850"
                     /pseudo=""
     CDS             <1..4944
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PCP (50-119). E-value: 4.3e-25. Score:
                     79.7. Matches aSDomain: nrpspksdomains_CE053_RS12850_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (133-421). E-value:
                     9.6e-111. Score: 361.5. Matches aSDomain:
                     nrpspksdomains_CE053_RS12850_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (586-980). E-value:
                     3.2e-112. Score: 367.0. Matches aSDomain:
                     nrpspksdomains_CE053_RS12850_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1087-1154). E-value: 1.4e-27.
                     Score: 87.7. Matches aSDomain:
                     nrpspksdomains_CE053_RS12850_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1164-1472). E-value:
                     2.2e-156. Score: 513.7. Matches aSDomain:
                     nrpspksdomains_CE053_RS12850_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1484-1640). E-value: 3e-45.
                     Score: 145.8. Matches aSDomain:
                     nrpspksdomains_CE053_RS12850_TIGR01720.1"
                     /codon_start=1
                     /gene="ppsD"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389713.2"
                     /locus_tag="CE053_RS12850"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsD"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 1.7e-99, bitscore:
                     328.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.3e-121, bitscore:
                     399.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-15, bitscore:
                     52.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPDGAADAETYTA
                     PRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRISKEFDVQVPLKEVF
                     AHPTVEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAV
                     LELEGKLNPERMDRAFKELIKRHESLRTSFKQDAGGDPVQRIHDEAPFTLQTTVLGART
                     EQEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELY
                     NNRNLPALRIQYKDYAVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRS
                     FAGDKVSFTLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGR
                     PHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLEL
                     TRDMSRNPVFDAMLVVQNNDYEPLHLHDLQMKPAQVSHLVSKFDLTLQASEGDGNIHFL
                     FEYSTALFEKTTIERWASHLTNVLSIIGKNPEVTLNHIDILTQEERHQLLNEFNTGQAN
                     QYGVQTISQLFEQQAARTPKASALVSGDKTLTYQELDEWSNGIARALRSRGVKPDTPVG
                     IMMHRSFSMIASILGVWKAGGCYVPIDPEYPTERKRYILSDSGTKLLMTINEADREALA
                     DFEGEILAIESVEADDKSPLPQMSSAHHLAYIIYTSGTTGHPKGVMVEHKGIANTLQWR
                     RNAYAFNETDTILQLFSFSFDGFLTSMFTPLLSGAKAVLLHEEEAKDILAIKHQLSCQR
                     ITHMIIVPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIHRSLAICPHTELANEYGP
                     TENSVATTAMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGLARGY
                     VNLPELTERAFTQNPFKPETRMYRTGDAARWMADGTLEYLGRIDDQVKIRGYRVETKEI
                     ESVIRCINGVKDAAVVAHETASGQTELSAYVVAKPELSTNAVRSELQNKLPVFMHPAFI
                     ERLDSLPLSSNGKLDRRALPKPVSKSGAERPFLPPASKMEQILADIWKEVLGAEKIGTA
                     DSFFELGGDSIKALQVSARLHRLGKQMAVKDLFSHPTIQELAAYIRDSDTSSSQAPVEG
                     DVQWSPVQKWFLSQDIKEKHHFNQSVMLYRSTSVQEDALRKTLKAITCHHDALRMVFTQ
                     NEQGKWDQYNRPLSHSDDALYGLQMIDLCTDGNRAYEPIIKRHVLDIQQKMDLKNGPLL
                     QAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAGGEDIKLPPKTSSFKAY
                     AKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDHIDGTRAHEGQRSTISFTLNDKETA
                     ALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHGREDVLEGIDVSRTVGW
                     FTAIYPLLVKLNADLPDSEEYMVHVLKTTKDTLRRVPDKGFGYGVIKYLTPPGKKDINF
                     TGAPEISFNYLGQFESGRSAEVPEEDAFSFSPLGAGGDISTTWNREQSLDISAIAAEGK
                     LTVNMTYDNARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEKTISDYDDQELTEDALQ
                     EIADMLSFH"
     CDS_motif       73..99
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0001"
                     /evalue="3.80E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="CE053_RS12850"
                     /protein_end="32"
                     /protein_start="23"
                     /score="4.2"
                     /tool="antismash"
                     /translation="GKLDRNALP"
     aSDomain        154..360
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12850_PCP.1"
                     /evalue="4.30E-25"
                     /label="CE053_RS12850_PCP.1"
                     /locus_tag="CE053_RS12850"
                     /protein_end="119"
                     /protein_start="50"
                     /score="79.7"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRISKEFD
                     VQVPLKEVFAHPTVEGLATVIREG"
     aSDomain        403..1266
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12850_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="9.60E-111"
                     /label="CE053_RS12850_Condensation_LCL.1"
                     /locus_tag="CE053_RS12850"
                     /protein_end="421"
                     /protein_start="133"
                     /score="361.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIISDG"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRA
                     FKELIKRHESLRTSFKQDAGGDPVQRIHDEAPFTLQTTVLGARTEQEAAAAFIKPFDLS
                     QAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPALRIQYKDY
                     AVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVA
                     SGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNT
                     LALRTRP"
     aSModule        403..4923
                     /complete
                     /domains="nrpspksdomains_CE053_RS12850_Condensation_LCL.1"
                     /domains="nrpspksdomains_CE053_RS12850_AMP-binding.1"
                     /domains="nrpspksdomains_CE053_RS12850_PCP.2"
                     /domains="nrpspksdomains_CE053_RS12850_Epimerization.1"
                     /domains="nrpspksdomains_CE053_RS12850_TIGR01720.1"
                     /locus_tags="CE053_RS12850"
                     /monomer_pairings="Tyr -> D-Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       475..582
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0002"
                     /evalue="8.20E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="CE053_RS12850"
                     /protein_end="193"
                     /protein_start="157"
                     /score="53.6"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTSF"
     CDS_motif       781..846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0003"
                     /evalue="6.10E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="CE053_RS12850"
                     /protein_end="281"
                     /protein_start="259"
                     /score="31.6"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       877..906
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0004"
                     /evalue="1.60E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="CE053_RS12850"
                     /protein_end="301"
                     /protein_start="291"
                     /score="14.3"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       1168..1257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0005"
                     /evalue="1.90E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="CE053_RS12850"
                     /protein_end="418"
                     /protein_start="388"
                     /score="49.2"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       1306..1422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0006"
                     /evalue="4.90E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="CE053_RS12850"
                     /protein_end="473"
                     /protein_start="434"
                     /score="63.9"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPVFDAMLV"
     aSDomain        1762..2943
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12850_AMP-binding.1"
                     /evalue="3.20E-112"
                     /label="CE053_RS12850_AMP-binding.1"
                     /locus_tag="CE053_RS12850"
                     /protein_end="980"
                     /protein_start="586"
                     /score="367.0"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEQQAARTPKASALVSGDKTLTYQELDEWSNGIARALRSRGVKPD
                     TPVGIMMHRSFSMIASILGVWKAGGCYVPIDPEYPTERKRYILSDSGTKLLMTINEADR
                     EALADFEGEILAIESVEADDKSPLPQMSSAHHLAYIIYTSGTTGHPKGVMVEHKGIANT
                     LQWRRNAYAFNETDTILQLFSFSFDGFLTSMFTPLLSGAKAVLLHEEEAKDILAIKHQL
                     SCQRITHMIIVPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIHRSLAICPHTELAN
                     EYGPTENSVATTAMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGL
                     ARGYVNLPELTERAFTQNPFKPETRMYRTGDAARWMADGTLEYLGRIDDQVKIR"
     CDS_motif       1948..1989
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0007"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="CE053_RS12850"
                     /protein_end="662"
                     /protein_start="648"
                     /score="18.0"
                     /tool="antismash"
                     /translation="LGVWKAGGCYVPID"
     CDS_motif       2173..2232
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0008"
                     /evalue="1.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="CE053_RS12850"
                     /protein_end="743"
                     /protein_start="723"
                     /score="32.6"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGHPKGVMVEH"
     CDS_motif       2737..2826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0009"
                     /evalue="3.70E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="CE053_RS12850"
                     /protein_end="941"
                     /protein_start="911"
                     /score="48.0"
                     /tool="antismash"
                     /translation="PIGVAGELCIAGTGLARGYVNLPELTERAF"
     CDS_motif       2908..2973
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0010"
                     /evalue="4.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="CE053_RS12850"
                     /protein_end="990"
                     /protein_start="968"
                     /score="34.7"
                     /tool="antismash"
                     /translation="YLGRIDDQVKIRGYRVETKEIE"
     CDS_motif       3181..3207
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0011"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1068"
                     /protein_start="1059"
                     /score="5.4"
                     /tool="antismash"
                     /translation="GKLDRRALP"
     aSDomain        3265..3465
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12850_PCP.2"
                     /evalue="1.40E-27"
                     /label="CE053_RS12850_PCP.2"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1154"
                     /protein_start="1087"
                     /score="87.7"
                     /tool="antismash"
                     /translation="EQILADIWKEVLGAEKIGTADSFFELGGDSIKALQVSARLHRLGK
                     QMAVKDLFSHPTIQELAAYIRD"
     aSDomain        3496..4419
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12850_Epimerization.1"
                     /evalue="2.20E-156"
                     /label="CE053_RS12850_Epimerization.1"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1472"
                     /protein_start="1164"
                     /score="513.7"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="EGDVQWSPVQKWFLSQDIKEKHHFNQSVMLYRSTSVQEDALRKTL
                     KAITCHHDALRMVFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLCTDGNRAYEPIIKRH
                     VLDIQQKMDLKNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAG
                     GEDIKLPPKTSSFKAYAKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDHIDGTRAHE
                     GQRSTISFTLNDKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHG
                     REDVLEGIDVSRTVGWFTAIYPLLVKL"
     CDS_motif       3646..3687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0012"
                     /evalue="1.40E-03"
                     /label="Cy2"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1228"
                     /protein_start="1214"
                     /score="11.3"
                     /tool="antismash"
                     /translation="HHDALRMVFTQNEQ"
     CDS_motif       3892..3957
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0013"
                     /evalue="3.00E-11"
                     /label="NRPS-E2"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1318"
                     /protein_start="1296"
                     /score="35.5"
                     /tool="antismash"
                     /translation="LFLSAHHLVVDGISWRVLLEDL"
     CDS_motif       4363..4410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0014"
                     /evalue="2.20E-08"
                     /label="NRPS-E5"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1469"
                     /protein_start="1453"
                     /score="26.1"
                     /tool="antismash"
                     /translation="DVSRTVGWFTAIYPLL"
     aSDomain        4456..4923
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12850_TIGR01720.1"
                     /evalue="3.00E-45"
                     /label="CE053_RS12850_TIGR01720.1"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1640"
                     /protein_start="1484"
                     /score="145.8"
                     /tool="antismash"
                     /translation="HVLKTTKDTLRRVPDKGFGYGVIKYLTPPGKKDINFTGAPEISFN
                     YLGQFESGRSAEVPEEDAFSFSPLGAGGDISTTWNREQSLDISAIAAEGKLTVNMTYDN
                     ARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEKTISDYDDQELTEDALQEI"
     CDS_motif       4471..4533
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0015"
                     /evalue="1.30E-09"
                     /label="NRPS-E6"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1510"
                     /protein_start="1489"
                     /score="30.2"
                     /tool="antismash"
                     /translation="TKDTLRRVPDKGFGYGVIKYL"
     CDS_motif       4573..4602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12850_0016"
                     /evalue="5.60E-03"
                     /label="NRPS-E7"
                     /locus_tag="CE053_RS12850"
                     /protein_end="1533"
                     /protein_start="1523"
                     /score="9.3"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     gene            4952..8791
                     /gene="ppsE"
                     /locus_tag="CE053_RS12855"
     CDS             4952..8791
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (7-36). E-value: 8.2e-16.
                     Score: 49.0. Matches aSDomain:
                     nrpspksdomains_CE053_RS12855_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (15-316). E-value:
                     1e-118. Score: 387.8. Matches aSDomain:
                     nrpspksdomains_CE053_RS12855_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (481-874). E-value: 2e-109.
                     Score: 357.8. Matches aSDomain:
                     nrpspksdomains_CE053_RS12855_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (980-1047). E-value: 1.6e-22. Score:
                     71.4. Matches aSDomain: nrpspksdomains_CE053_RS12855_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1067-1271). E-value:
                     8.2e-41. Score: 132.8. Matches aSDomain:
                     nrpspksdomains_CE053_RS12855_Thioesterase.1"
                     /codon_start=1
                     /gene="ppsE"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389712.1"
                     /locus_tag="CE053_RS12855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsE"
                     /protein_id="WP_163182370.1"
                     /sec_met_domain="Condensation (E-value: 3.8e-89, bitscore:
                     294.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-113, bitscore:
                     373.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-15, bitscore:
                     52.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.2e-23, bitscore:
                     79.0, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKGADTMDNIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQSL
                     FTIKGSLSYEWFQRSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLYSEDISH
                     LPTNDQNEYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLG
                     IVMQEFMQIYQSIHAGKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSTPSPL
                     PRVSDKETKEGYHREDLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTD
                     DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIRIKTHQDETFQELLIRCQKEMLEAEPFT
                     CQPLFDIQANTALKQELIDHIIVFENYPLQQKIADSADQTDSPLQIDQVQVSEQSGYNF
                     NLVVAPGEELVVKFSYNAFVYDAAWISCIKRQFTQALSTAAQHPHMPIADFSFLDATEK
                     EQIVTQFNNTKTEYPKNHTIIDLFREQAEKTPDHTALVYGNMSISYKELDKRSNALARE
                     LIQKGFRKNETAGILAAHSPEFMISVLAVLKAGGAYLPLDEELPPERVSFMLEETQAKM
                     LIVQKGLEQNAAFSGTCMIADAQALMGENHFPINTISSPDDLAYIMYTSGSTGRPKGVM
                     ITNRNVVSLVRNSNYTSASGDDRFIMTGSISFDAVTFEMFGSLLHGASLHIIDKSTMLT
                     PDRFGAYLLENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHAC
                     PDLALHNIYGPTENTTFSTFFEIKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGE
                     LCVGGDGVAKGYLNRDDMTNTVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQM
                     KIRGKRIEPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYVGDHKKTDTDFRADLAR
                     VLPDYMIPQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQNIILPRNLVEEELANIWK
                     QVLGVNTISIDDDFFAIGGHSLKALHVIHTLKHQQNIDIPIDFLFEHPTIAQLAEKLYS
                     KQLTAADEQHVIKLNQHGAQNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTR
                     IEQYVNCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLP
                     IDTGNDESAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIQIETSENT
                     SLTKWEGACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITSNQVILHKR"
     aSDomain        4973..5059
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12855_NRPS-COM_Nterm.1"
                     /evalue="8.20E-16"
                     /label="CE053_RS12855_NRPS-COM_Nterm.1"
                     /locus_tag="CE053_RS12855"
                     /protein_end="36"
                     /protein_start="7"
                     /score="49.0"
                     /tool="antismash"
                     /translation="MDNIKKIKNIYPLSHMQEGMLFHSFLRKE"
     aSDomain        4997..5899
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12855_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.00E-118"
                     /label="CE053_RS12855_Condensation_DCL.1"
                     /locus_tag="CE053_RS12855"
                     /protein_end="316"
                     /protein_start="15"
                     /score="387.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILMDG"
                     /tool="antismash"
                     /translation="NIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSLSYEWFQRS
                     IQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLYSEDISHLPTNDQNEYIERFKE
                     KDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHA
                     GKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSTPSPLPRVSDKETKEGYHRE
                     DLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEI
                     PGVEQMIGLFINTIPIRIKT"
     aSModule        4997..8764
                     /complete
                     /domains="nrpspksdomains_CE053_RS12855_Condensation_DCL.1"
                     /domains="nrpspksdomains_CE053_RS12855_AMP-binding.1"
                     /domains="nrpspksdomains_CE053_RS12855_PCP.1"
                     /domains="nrpspksdomains_CE053_RS12855_Thioesterase.1"
                     /final_module
                     /locus_tags="CE053_RS12855"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5003..5044
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0001"
                     /evalue="3.90E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="CE053_RS12855"
                     /protein_end="31"
                     /protein_start="17"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS_motif       5063..5179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0002"
                     /evalue="9.90E-16"
                     /label="C2_DCL_024-062"
                     /locus_tag="CE053_RS12855"
                     /protein_end="76"
                     /protein_start="37"
                     /score="50.0"
                     /tool="antismash"
                     /translation="GAYVEQSLFTIKGSLSYEWFQRSIQAIIDRHDIFRTVFL"
     CDS_motif       5405..5470
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0003"
                     /evalue="1.00E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="CE053_RS12855"
                     /protein_end="173"
                     /protein_start="151"
                     /score="40.3"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVMQEFMQIY"
     CDS_motif       5795..5890
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0004"
                     /evalue="1.30E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="CE053_RS12855"
                     /protein_end="313"
                     /protein_start="281"
                     /score="69.0"
                     /tool="antismash"
                     /translation="DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIR"
     CDS_motif       5939..6055
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0005"
                     /evalue="1.40E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="CE053_RS12855"
                     /protein_end="368"
                     /protein_start="329"
                     /score="52.9"
                     /tool="antismash"
                     /translation="QKEMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYP"
     aSDomain        6395..7573
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12855_AMP-binding.1"
                     /evalue="2.00E-109"
                     /label="CE053_RS12855_AMP-binding.1"
                     /locus_tag="CE053_RS12855"
                     /protein_end="874"
                     /protein_start="481"
                     /score="357.8"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFRKN
                     ETAGILAAHSPEFMISVLAVLKAGGAYLPLDEELPPERVSFMLEETQAKMLIVQKGLEQ
                     NAAFSGTCMIADAQALMGENHFPINTISSPDDLAYIMYTSGSTGRPKGVMITNRNVVSL
                     VRNSNYTSASGDDRFIMTGSISFDAVTFEMFGSLLHGASLHIIDKSTMLTPDRFGAYLL
                     ENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHNIY
                     GPTENTTFSTFFEIKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDGVA
                     KGYLNRDDMTNTVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIR"
     CDS_motif       6581..6622
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0006"
                     /evalue="8.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="CE053_RS12855"
                     /protein_end="557"
                     /protein_start="543"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       6806..6862
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0007"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="CE053_RS12855"
                     /protein_end="637"
                     /protein_start="618"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGRPKGVMIT"
     CDS_motif       7367..7456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0008"
                     /evalue="8.20E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="CE053_RS12855"
                     /protein_end="835"
                     /protein_start="805"
                     /score="46.9"
                     /tool="antismash"
                     /translation="PIGVPGELCVGGDGVAKGYLNRDDMTNTVF"
     CDS_motif       7538..7603
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0009"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="CE053_RS12855"
                     /protein_end="884"
                     /protein_start="862"
                     /score="30.2"
                     /tool="antismash"
                     /translation="YISRIDRQMKIRGKRIEPAEIE"
     aSDomain        7892..8092
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12855_PCP.1"
                     /evalue="1.60E-22"
                     /label="CE053_RS12855_PCP.1"
                     /locus_tag="CE053_RS12855"
                     /protein_end="1047"
                     /protein_start="980"
                     /score="71.4"
                     /tool="antismash"
                     /translation="EEELANIWKQVLGVNTISIDDDFFAIGGHSLKALHVIHTLKHQQN
                     IDIPIDFLFEHPTIAQLAEKLY"
     aSDomain        8153..8764
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12855_Thioesterase.1"
                     /evalue="8.20E-41"
                     /label="CE053_RS12855_Thioesterase.1"
                     /locus_tag="CE053_RS12855"
                     /protein_end="1271"
                     /protein_start="1067"
                     /score="132.8"
                     /tool="antismash"
                     /translation="QNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYV
                     NCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGN
                     DESAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIQIETSENTSLTKW
                     EGACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITS"
     CDS_motif       8306..8377
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12855_0010"
                     /evalue="3.10E-13"
                     /label="NRPS-te1"
                     /locus_tag="CE053_RS12855"
                     /protein_end="1142"
                     /protein_start="1118"
                     /score="42.0"
                     /tool="antismash"
                     /translation="QPEGPYVLLGYSAGGNLAFEVAQA"
     gene            8902..9294
                     /gene="yngL"
                     /locus_tag="CE053_RS12860"
     CDS             8902..9294
                     /codon_start=1
                     /gene="yngL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389711.1"
                     /locus_tag="CE053_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1360 domain-containing protein"
                     /protein_id="WP_003231518.1"
                     /transl_table=11
                     /translation="MDRLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRIVDQ
                     NGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQAIL
                     ETAVGVGVKLIDVLKSLQTMMNDKKS"
     gene            9427..10959
                     /gene="yngK"
                     /locus_tag="CE053_RS12865"
     CDS             9427..10959
                     /codon_start=1
                     /gene="yngK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389710.1"
                     /locus_tag="CE053_RS12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="WP_163182324.1"
                     /transl_table=11
                     /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASVL
                     NIDWPSKKGLSVKEQKQEYIKLLDDVQKMGMNAVIVQIKPMADAFYPSAYGPWSEYLTG
                     VQGKDPGYDPLAFIIKETHKRNLEFHAWFNPYRITMNHTDLNKLSEDHPARKHPDWVAA
                     YGNQLYYHPGIPEARDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQYEQY
                     GKDAFSNIDDWRRDNVNQLVKQINQTIKAAKPYVKFGISPFGVWRNAADDPTGSNTKAG
                     VRNYDDLYADTRRWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRPVHLYIG
                     QAAYKINNNFDPPWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLGIKDSLSTDL
                     YSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNQKTKETAYYAIYRAEG
                     KKQRTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRTTK"
     gene            11043..11195
                     /locus_tag="CE053_RS12870"
     CDS             11043..11195
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009513961.1"
                     /locus_tag="CE053_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_041055511.1"
                     /transl_table=11
                     /translation="MFGHFPLLESEKLVLSKIEEKHVQDVFYVFISSLVRCHIIFCAVR
                     RCCVD"
     gene            11185..11490
                     /gene="ynzE"
                     /locus_tag="CE053_RS12875"
     CDS             11185..11490
                     /codon_start=1
                     /gene="ynzE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389709.1"
                     /locus_tag="CE053_RS12875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5367 family protein"
                     /protein_id="WP_085187717.1"
                     /transl_table=11
                     /translation="MLTDPAEEAFLMNFLLLEAGTALVLCLVFFLYQKLDQSQFAVIKL
                     GIWGSAVGLLIDTISLWNHPLILPALSKGQVIAFAIWMVCAYCMYLLIPLKLSHKK"
     misc_feature    11551..11568
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.6"
                     /tool="antismash"
     gene            11581..12723
                     /gene="ldeJ"
                     /locus_tag="CE053_RS12880"
     CDS             11581..12723
                     /codon_start=1
                     /gene="ldeJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389708.1"
                     /locus_tag="CE053_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_085187642.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5e-39, bitscore:
                     128.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.2e-27, bitscore:
                     91.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.8e-55, bitscore:
                     180.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFEKM
                     GELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTE
                     EQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYA
                     RTVIVTAVTGKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPA
                     ANLLGDPTKGFKQFLYTLDGGRISIASLAVGIAQAALDASLAYAKERKQFGQPISSFQA
                     IQFKLADMAMEIDLARQMVLKAAWLKDHNHPFTKEAAYAKLFASEMATRACNQAIQIHG
                     GSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK"
     misc_feature    complement(12728..12739)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            12767..14416
                     /gene="ldeI"
                     /locus_tag="CE053_RS12885"
     CDS             12767..14416
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 1.1e-105.
                     Score: 345.6. Matches aSDomain:
                     nrpspksdomains_CE053_RS12885_AMP-binding.1"
                     /codon_start=1
                     /gene="ldeI"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389707.1"
                     /locus_tag="CE053_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_014479959.1"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-115, bitscore:
                     379.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCR
                     QTAKGLMRMGIGKGDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQ
                     SDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLAGMY
                     HWDETEILAKTVTDAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANI
                     AECMALTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCT
                     ALHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQ
                     TEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVM
                     KGYYKDKEATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEF
                     LYRHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIARHKIPRYVI
                     FTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ"
     misc_feature    complement(12768..12782)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.44"
                     /tool="antismash"
     aSDomain        12806..14101
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12885_AMP-binding.1"
                     /evalue="1.10E-105"
                     /label="CE053_RS12885_AMP-binding.1"
                     /locus_tag="CE053_RS12885"
                     /protein_end="445"
                     /protein_start="13"
                     /score="345.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGK
                     GDHVAIWASNIPEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYR
                     GTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLAGMYHWDETEILAKTVT
                     DAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMALTSQDRMC
                     IPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTALHGVPTMFIAEL
                     HHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRAN
                     DSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVMKGYYKDKEATRKA
                     INHDGWLFTGDLAVMDEDGYCRITGRLKDMLIR"
     CDS_motif       13352..13402
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12885_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="CE053_RS12885"
                     /protein_end="212"
                     /protein_start="195"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS_motif       13922..13999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CE053_RS12885_0002"
                     /evalue="2.50E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="CE053_RS12885"
                     /protein_end="411"
                     /protein_start="385"
                     /score="13.5"
                     /tool="antismash"
                     /translation="GMQGELCTRGYHVMKGYYKDKEATRK"
     gene            14426..15760
                     /gene="ldeHA"
                     /locus_tag="CE053_RS12890"
     CDS             14426..15760
                     /codon_start=1
                     /gene="ldeHA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389706.1"
                     /locus_tag="CE053_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_120363435.1"
                     /sec_met_domain="ATP-grasp (E-value: 4.6e-09, bitscore:
                     31.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.6e-16,
                     bitscore: 54.2, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDALHTKAA
                     TEAYLIGESRVSESYLNIERIIKTAKKANADAIHPGYGLLSENSRFAERCKQENIVFIG
                     PSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTAGQIGYPVMLKASAGG
                     GGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTV
                     HLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEFIVDQK
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIKRNGHAIEVRIY
                     AEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAI
                     EKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL"
     gene            15775..15996
                     /gene="lgeHB"
                     /locus_tag="CE053_RS12895"
     CDS             15775..15996
                     /codon_start=1
                     /gene="lgeHB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097733.1"
                     /locus_tag="CE053_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_017696500.1"
                     /transl_table=11
                     /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADIS
                     GIVKEVKKNEGDFVNEGDVLLELSDSTQ"
     gene            16011..16910
                     /gene="ldeG"
                     /locus_tag="CE053_RS12900"
     CDS             16011..16910
                     /codon_start=1
                     /gene="ldeG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389705.1"
                     /locus_tag="CE053_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_038827842.1"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-49, bitscore:
                     164.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYI
                     EITSFVHPKWIPALRDAIDVAKGIDRLKGVTYAALVPNQRGLENALEGGINEACVFMSA
                     SETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVIRLS
                     EALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTA
                     LQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIE
                     EKMGKPLPSRNLQVFKSS"
     gene            16931..17713
                     /gene="ldeF"
                     /locus_tag="CE053_RS12905"
     CDS             16931..17713
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (10-252). E-value: 1.4e-70. Score:
                     229.3. Matches aSDomain:
                     nrpspksdomains_CE053_RS12905_ECH.1"
                     /codon_start=1
                     /gene="ldeF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389704.1"
                     /locus_tag="CE053_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_070549077.1"
                     /transl_table=11
                     /translation="MGDSILFTVKNEHIALITLNRPQAANALSAEMLRNLQMIIQEIEF
                     NSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAI
                     NGSALGGGLELALACDLRIATESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIY
                     TGRRVTAHEAKEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDL
                     ATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI"
     aSDomain        16961..17686
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CE053_RS12905_ECH.1"
                     /evalue="1.40E-70"
                     /label="CE053_RS12905_ECH.1"
                     /locus_tag="CE053_RS12905"
                     /protein_end="252"
                     /protein_start="10"
                     /score="229.3"
                     /tool="antismash"
                     /translation="NEHIALITLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILT
                     GTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLE
                     LALACDLRIATESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEA
                     KEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKA
                     YEQTIPTKDRREGLQAFQEK"
     gene            17724..19259
                     /gene="ldeE"
                     /locus_tag="CE053_RS12910"
     CDS             17724..19259
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ldeE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389703.2"
                     /locus_tag="CE053_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_072174027.1"
                     /transl_table=11
                     /translation="MLMDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFD
                     DDIELEDAFFAECMSDGLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIR
                     IQETAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGP
                     SAAGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGD
                     ILAETEEEAIQLARAYLSYFPANFQEKAPIHKKRPPKHFDTPLADVIPQNQNAPFDMHE
                     LIERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKF
                     ITLCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYG
                     AGLYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREE
                     YKEDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV"
     gene            19429..20628
                     /gene="nrnB"
                     /locus_tag="CE053_RS12915"
     CDS             19429..20628
                     /codon_start=1
                     /gene="nrnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389702.1"
                     /locus_tag="CE053_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oligoribonuclease NrnB"
                     /protein_id="WP_163182325.1"
                     /transl_table=11
                     /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEVRYNSVNGLNAQVQYFL
                     EKAKESNRQDALFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFVKV
                     EYDDGRLTSATSLLYGYLVENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRLNDL
                     FFLLSIDEFEEKMIQRLSTHDEFFFDDFEEKLLDLEDEKIERYLRRKKREMVQTFVHEH
                     CVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDYIDVSEIAGRYGGG
                     GHAKASGCSITDEVYELFVAEAFRIDPVRPDAFRNIYNLKGSANGSLYENRAQMRFFLF
                     PLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLKLANQHRK
                     "
     gene            complement(20677..21273)
                     /gene="uptA"
                     /locus_tag="CE053_RS12920"
     CDS             complement(20677..21273)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uptA"
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389701.1"
                     /locus_tag="CE053_RS12920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DedA family protein"
                     /protein_id="WP_003231529.1"
                     /transl_table=11
                     /translation="MGSLISEILTWLTNMGYAGIAIGLMIEIIPSEIVLAYGGYMVSEG
                     TIGFIGAIIAGVIGGTIAQIFIYWIGRYGGRPFLDKYGKYLLIKKHHIDMSENWFQKYG
                     AGVVFSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQWDD
                     VENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR"
     gene            complement(21346..22239)
                     /gene="galU"
                     /locus_tag="CE053_RS12925"
     CDS             complement(21346..22239)
                     /EC_number="2.7.7.9"
                     /GO_function="GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="galU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389700.1"
                     /locus_tag="CE053_RS12925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="WP_003245127.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.9e-10, bitscore:
                     36.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEE
                     AAESGIEDILIITGRNKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIR
                     QKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSV
                     LPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIG
                     RGAGNEIQLTDALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLL
                     AYLEDVIKRETKEMLR"
     gene            complement(22246..22692)
                     /gene="gtrA"
                     /locus_tag="CE053_RS12930"
     CDS             complement(22246..22692)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="gtrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389699.1"
                     /locus_tag="CE053_RS12930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GtrA family protein"
                     /protein_id="WP_014479951.1"
                     /transl_table=11
                     /translation="MTATRIFYEGRSVTLKEKIKTLGRFCTVGVGNTLIDFGVFFLLTA
                     CHVSYLPAQICSYTAGIVNSYVWNRNWTFCVKRKADGKEIVRFLMINIAASGITFLLLY
                     LFQNCGCSLLVSKLAATIGGMMMNFIGNRIWVFGDSLKNIQDQE"
     misc_feature    complement(23093..23108)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.65"
                     /tool="antismash"
     misc_feature    23128..23137
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    23163..23176
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.17"
                     /tool="antismash"
     gene            23368..24909
                     /gene="xynD"
                     /locus_tag="CE053_RS12935"
     CDS             23368..24909
                     /EC_number="3.2.1.55"
                     /codon_start=1
                     /gene="xynD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389698.1"
                     /locus_tag="CE053_RS12935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha-L-arabinofuranosidase"
                     /protein_id="WP_163182326.1"
                     /transl_table=11
                     /translation="MRKKCSVCLFVFALLLSCLSGKSAYAATSSTIAKHVGNSNPLIDH
                     HLGADPIALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNKVFVISSADMVNWTDHGA
                     IPVAGANGANGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADSPIG
                     PWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGGSNPTQGQWANP
                     KTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPADKPPG
                     EIGYMTSSNPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQTVSSALF
                     GAGKGYRSPHINKLVHNPDGSIQEVAANYAGVTQLSNLNPYNRVEAETFAWNGRILTEK
                     STAPGGPVNNQHVTSIQNGDWIAVGNADFGAVGARSFKANVASTSGGKIEVRLDSADGK
                     LVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFNFDYWQFTQR"
     gene            25040..26308
                     /gene="xynC"
                     /locus_tag="CE053_RS12940"
     CDS             25040..26308
                     /EC_number="3.2.1.136"
                     /codon_start=1
                     /gene="xynC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389697.1"
                     /locus_tag="CE053_RS12940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucuronoarabinoxylan endo-1,4-beta-xylanase
                     XynC"
                     /protein_id="WP_029317861.1"
                     /transl_table=11
                     /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEKQ
                     VIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAKSA
                     VKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYNKYAAYAQHLNDFVTFMKNNGVNL
                     YAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPILNDPQ
                     ALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDNNSADRWPEALDVS
                     QHIHNAMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVRIDATKN
                     PNANVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSNLQPGTNL
                     TVSGNHFWAHLPAQSVTTFVVNR"
     gene            complement(26567..26830)
                     /gene="ynfE"
                     /locus_tag="CE053_RS12945"
     CDS             complement(26567..26830)
                     /codon_start=1
                     /gene="ynfE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389696.1"
                     /locus_tag="CE053_RS12945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YnfE family protein"
                     /protein_id="WP_003231535.1"
                     /transl_table=11
                     /translation="MDEILKQYMVLYKKMSNMINGPDYPGKEKDIQHQKDQIEVYEKQL
                     QQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF"
     gene            complement(26897..28396)
                     /gene="eglS"
                     /locus_tag="CE053_RS12950"
     CDS             complement(26897..28396)
                     /EC_number="3.2.1.4"
                     /codon_start=1
                     /gene="eglS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389695.2"
                     /locus_tag="CE053_RS12950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endo-1,4-beta-glucanase EglS"
                     /protein_id="WP_003231540.1"
                     /transl_table=11
                     /translation="MKRSISIFITCLLITLLTMGGMIASPASAAGTKTPVAKNGQLSIK
                     GTQLVNRDGKAVQLKGISSHGLQWYGEYVNKDSLKWLRDDWGITVFRAAMYTADGGYID
                     NPSVKNKVKEAVEAAKELGIYVIIDWHILNDGNPNQNKEKAKEFFKEMSSLYGNTPNVI
                     YEIANEPNGDVNWKRDIKPYAEEVISVIRKNDPDNIIIVGTGTWSQDVNDAADDQLKDA
                     NVMYALHFYAGTHGQFLRDKANYALSKGAPIFVTEWGTSDASGNGGVFLDQSREWLKYL
                     DSKTISWVNWNLSDKQESSSALKPGASKTGGWRLSDLSASGTFVRENILGTKDSTKDIP
                     ETPSKDKPTQENGISVQYRAGDGSMNSNQIRPQLQIKNNGNTTVDLKDVTARYWYKAKN
                     KGQNFDCDYAQIGCGNVTHKFVTLHKPKQGADTYLELGFKNGTLAPGASTGNIQLRLHN
                     DDWSNYAQSGDYSFFKSNTFKTTKKITLYDQGKLIWGTEPN"
ORIGIN
        1 agactgctgc cgggctacat ggtcccagcc tatatgatag agatggaaca gtggccggtt
       61 acaccaagcg gaaagcttga ccgaaacgcc ctgccagctc ctgacggagc ggcagatgcg
      121 gagacctaca cggcgccgag aaacgtgact gagatgaagc tttctcagct gtgggaggac
      181 gtgctgaaaa atggccctgt cgggattcac gacaactttt ttgaccgcgg gggacattcc
      241 ttaaaagcaa cggcgcttgt ctcacggatc tcaaaagaat tcgatgtaca ggtgccgcta
      301 aaagaggtgt ttgcccatcc gacagtagaa gggctggcta ccgttatccg tgaaggaacg
      361 gacagtccat atgaagcgat taagcccgct gaaaaacagg aaacctatcc ggtttcctct
      421 gcccaaaagc ggatttatgt ccttcagcag ctggaggacg gagggacagg ctacaatatg
      481 ccggctgtgt tagagctcga agggaagctc aaccctgaaa ggatggacag agctttcaaa
      541 gagctgatca agcgccacga gtcgcttcgg acctccttca aacaggacgc aggaggcgat
      601 ccggtgcagc gcatccatga cgaggcgccg tttacgttac agactacagt tctcggcgca
      661 cgaaccgaac aggaggccgc agccgcattt atcaaaccgt ttgatctcag ccaagcgccg
      721 ctgttccgtg cccaaatcgt aaaggtatca gatgagcggc acctgttgct ggttgatatg
      781 catcacatca tttcagacgg tgtttccgtc aacattctga ttcgggaatt cggcgagctg
      841 tacaataatc ggaatcttcc ggcgctgcgc attcaatata aagattatgc cgtatggcaa
      901 gaaggattca aaacaggaga cgcgtacaaa acgcaagagg cgtactggct gaagcagctc
      961 gagggcgagc tgcctgtgct ggatcttccg gctgatcatg cccgcccgcc ggtgcgaagc
     1021 ttcgcgggtg acaaggtctc atttacgctg gatcaagagg ttgcatcagg ccttcacaag
     1081 ctggcacgag aaaacggaag cacactgtac atggtgcttc ttgcggctta caccgcgttc
     1141 ttgtcacgct taagcggaca ggaagatatc atcgtcggct cgccaattgc cggccggccg
     1201 cacaaggatc ttgagccgat actcggcatg tttgtgaaca cgctggcgct tcggacgcgc
     1261 ccggagggcg ggaagccatt cgtacagtat ttgcaggaag tgcgtgagac agcattggaa
     1321 gcctttgagc accaggatta cccgttcgaa gagcttgtcg ataagcttga attgacacgg
     1381 gatatgagcc ggaatccagt gtttgatgcg atgttagttg ttcaaaataa tgattacgag
     1441 ccattgcatc ttcatgattt gcaaatgaag ccggcacaag tttctcatct cgtttctaaa
     1501 tttgatttga cactacaggc atctgaaggc gacggaaaca ttcatttcct ttttgaatat
     1561 tcaaccgcat tgttcgagaa aaccaccatt gaacgctggg catcgcattt aacaaatgta
     1621 cttagcatca tcggcaaaaa cccggaggtg acactcaacc atatcgacat cctgacccaa
     1681 gaagagcggc accagctgct taatgagttt aacaccgggc aagcgaatca atacggagtt
     1741 caaacaatca gtcaattgtt tgagcagcaa gctgcacgaa caccaaaagc ttctgcactt
     1801 gtcagcggag acaaaacact cacttatcag gagcttgacg agtggtccaa tggaatcgca
     1861 cgtgcattgc gcagccgagg tgttaagccg gacacaccag taggcatcat gatgcatcgt
     1921 tcgttcagta tgatagcatc catacttggt gtgtggaaag ccggaggctg ttacgttccc
     1981 atcgatcctg aatacccgac agaacggaaa cgctatatcc ttagcgacag cggaacgaaa
     2041 ctgctgatga caataaatga agcggatcgg gaagcacttg ctgactttga aggagagatc
     2101 ttagcgatag aaagtgtaga ggcagacgac aaatcgccgc tgccgcaaat gtcgtctgcc
     2161 catcatttgg cttatatcat ttatacctct ggaacgactg gccatccaaa aggggtaatg
     2221 gtcgagcata aaggtattgc caacactctt cagtggcggc gaaacgctta tgcattcaac
     2281 gagacagata ccattctgca gctcttttct ttctcatttg acggcttttt aactagtatg
     2341 tttacaccac ttttgtcagg tgcaaaagcc gttttgcttc atgaagagga agcgaaggat
     2401 attctggcca ttaagcatca gctgtcttgt cagcggatta cacatatgat tattgtgcct
     2461 gttttatatc gagcgctttt ggacgtagtg cagccggaag atgtaaagac gcttagagtc
     2521 gtcacactgg caggagaagc ggctgaccgc gaattgatcc atcgcagctt ggccatttgt
     2581 ccgcataccg aactcgccaa cgaatatgga ccgacagaaa acagcgtggc gactaccgcc
     2641 atgagacata tggaaaagca ggcatacgta agcatcggcc agccgattga cgggactcaa
     2701 gtgctgattt taaatagcaa tcatcagctt cagccaatcg gtgttgcggg agagctttgt
     2761 atagcaggaa cagggcttgc aagagggtac gtcaatcttc cagaactgac agagagagca
     2821 ttcacgcaga atccatttaa acccgaaaca cgaatgtacc gaacaggaga cgccgccaga
     2881 tggatggccg acggtacact cgaatatctc ggaagaatcg atgatcaagt caaaatcaga
     2941 ggataccgtg tagaaacgaa agaaattgaa tcggtcatcc ggtgtataaa tggtgtaaaa
     3001 gacgccgcag tagttgctca tgaaacagcg tcaggacaaa ccgaattaag tgcttatgtg
     3061 gtggcaaaac cagagttgag cacaaatgct gtacgctcag aattacaaaa caaactgccg
     3121 gtgtttatgc accctgcgtt tattgaaaga ctggattcac ttccattgtc atcaaacggc
     3181 aagctggatc gcagagcact accgaaaccc gtatcgaaga gcggagctga acgtccattc
     3241 ctcccgccag ccagcaaaat ggaacaaata ctggcagata tatggaaaga agtactgggg
     3301 gcagaaaaga tcggaacagc tgattcgttc tttgaacttg gcggagattc aatcaaagcg
     3361 ttacaggtat ctgcgcggct tcaccggtta ggcaagcaaa tggcagtgaa agatttgttt
     3421 agccatccga ccattcaaga attggcagct tatatccgtg attcagatac aagttccagc
     3481 caagctccgg ttgagggaga cgtacaatgg tcgcctgttc aaaaatggtt tctttctcaa
     3541 gatataaaag aaaaacacca ttttaatcag tccgtaatgc tgtatcgaag cacctctgta
     3601 caagaagacg cactgcgcaa aacgttaaaa gcaataacgt gtcatcatga tgcgctgaga
     3661 atggtgttta cacagaatga acaaggaaag tgggatcaat ataatcggcc gctcagtcat
     3721 tcggacgacg cgttgtacgg ccttcagatg attgatttat gcactgatgg aaatagagcg
     3781 tatgagccta ttatcaaacg ccatgtactt gatattcagc agaaaatgga tttgaagaat
     3841 ggtccgctgc tgcaagccgg tcttttccac acaattgacg gtgatttctt atttttatcg
     3901 gctcatcacc tcgtcgttga cggcatctca tggcgggttc tgcttgagga tttggcttta
     3961 gggtatcgcc aagctgctgg cggggaggat atcaaactgc cgcctaaaac aagctcgttt
     4021 aaagcgtatg cgaaaaagct ctctgactac gctgaaagcc agcagctaat gaaacagctc
     4081 aagtattggc gcgaagccga agagtatcaa acagaggcat tgccttttga tcacatcgat
     4141 ggcactagag cacacgaggg acaacggtcc acaatttcgt ttaccttaaa cgataaagag
     4201 acagcagcac tcttaaaaga cgccaacagc gcatataaca ctgatacgca ggacatgctg
     4261 ctcgcttctg tcattcttgc gctgcgccat tggaccaatc aatccgcctt caaactatca
     4321 ttagagggcc acgggcgaga ggatgtatta gaaggaatag atgtgagccg gacggttgga
     4381 tggtttaccg ccatttatcc gttattggtt aaattgaacg cagacttgcc agattcggaa
     4441 gaatacatgg ttcatgtgct aaaaacaaca aaagatacac tgagacgtgt acctgacaaa
     4501 ggattcggct acggtgtcat caaatatttg acgccgcctg gcaaaaaaga catcaatttc
     4561 acaggtgcac cagaaatcag ctttaattat cttggtcaat ttgaaagcgg ccgctcagct
     4621 gaagtacctg aggaggacgc cttctcattc tctccgcttg gtgccggagg tgatatcagc
     4681 acaacatgga accgtgaaca gtcgctggat atcagcgcaa tcgctgcaga aggaaaatta
     4741 actgtcaata tgacttatga caatgcccgc tttcagcgca aaaccatcga acagcttagc
     4801 gaaacatgcc gtcaattttt attacagctg atcgaacact gccagaacaa aagcgaaaca
     4861 gaaaagacga tcagcgatta tgatgatcaa gaactaaccg aggacgccct gcaagagatt
     4921 gctgatatgc tcagttttca ctaatgaaac cgtgaagaaa ggtgcagaca ctatggataa
     4981 catcaaaaaa atcaagaaca tttatcctct gagtcatatg caggagggaa tgctgtttca
     5041 ttccttcctc cgtaaagagg agggggcata cgttgagcag tcgctcttca ccattaaagg
     5101 aagcctcagc tatgaatggt ttcagcgcag cattcaagcc attatcgacc gccatgatat
     5161 tttcagaact gtgtttttgc cgcacgtccc gcatttgtcg ggacctcggc aagtcgtgat
     5221 gacagaacgt gaattccatt tgtacagcga agacatttct catctgccaa caaacgacca
     5281 gaatgagtat attgaacgct ttaaggagaa ggacaagcaa aaaggctttg atctgcaaaa
     5341 agacatgctg atgcggattt ctctattcaa aacagctaaa gatgagcatg tctgtatctg
     5401 gagtcaccat catattttaa tggacggatg gtgcctaggt attgttatgc aggaatttat
     5461 gcaaatttat caatcaattc atgcaggaaa accgctttca ttagaccctg tccgtccgta
     5521 cagcacctat atttcctggc tgacaaaccg agacaaagaa aaagcagcag cctactggga
     5581 tacctattta aaaaactaca gcactccatc acctctgcct cgtgtgtctg ataaagaaac
     5641 aaaagaaggt tatcaccgtg aagatttgat attttcatta aataaaccac tgacagacaa
     5701 gctgaaagag actgccaaac aacacggcgt cacgctcgct accctaattc aggcggtctg
     5761 gggtgtgatg ctgcagcaat ataaccgcac agacgacgtt gtgtttggcg cagttgtatc
     5821 aggaagaccg tcagaaatcc cgggcgtgga gcaaatgata gggttgttta tcaataccat
     5881 accgattcga attaaaacac atcaagacga aacgtttcaa gaactgctca tacgatgcca
     5941 gaaagaaatg ctggaagctg agccgtttac ctgccagcct ttatttgata ttcaggcaaa
     6001 caccgcatta aaacaggaac tgattgatca cattatcgtc tttgaaaact atccgttaca
     6061 gcagaaaatc gccgattccg ctgatcaaac cgattcaccg ctgcaaatcg atcaagttca
     6121 agtatccgag caatcaggat ataactttaa tcttgtcgtt gctcccggcg aagagcttgt
     6181 cgtcaagttc agctataatg cattcgttta cgatgctgcc tggatcagct gtatcaagag
     6241 gcaatttacg caagcgctta gcacagctgc acagcaccct catatgccaa ttgctgattt
     6301 ttcttttctt gatgcaacag aaaaagagca gattgtcaca cagttcaaca atacaaaaac
     6361 ggagtatcca aagaatcata caattatcga tttatttcgc gaacaagcag aaaagacgcc
     6421 agaccatacc gcacttgtgt atggcaatat gtctatttca tataaagagc ttgataaacg
     6481 ctctaatgcg ctcgccagag agttaattca aaagggattt cggaaaaacg agacagccgg
     6541 aatattggct gcacattctc ccgaattcat gatcagtgtg cttgccgtat taaaagcagg
     6601 gggagcatac ctcccgcttg atgaggagct tccgcctgaa cgagtcagct ttatgcttga
     6661 ggaaacgcaa gcaaaaatgc tgattgttca aaaggggctg gagcaaaatg ctgcgttctc
     6721 aggaacatgt atgattgcag atgcgcaggc attgatggga gagaaccatt ttcctatcaa
     6781 caccatctcc agtccagacg atcttgcata tatcatgtat acctcaggat caacaggccg
     6841 gccgaaaggg gtcatgatca cgaatcgcaa tgtcgtgtcc cttgtcagaa acagcaatta
     6901 cacgtctgcg tccggtgatg accggtttat tatgactgga tctatcagct ttgacgccgt
     6961 cacctttgaa atgttcgggt cacttttaca tggcgcaagc cttcatatca ttgataaatc
     7021 gacaatgctg acacctgatc ggtttggagc gtatttgctt gaaaatgaca tcacagtgct
     7081 atttttaacg acagctcttt ttaatcagct ggcacaggta cgagctgaca tgtttcgcgg
     7141 actccatacg ttatatgtcg gaggagaagc actttcgcct gctctgatga atgctgtcag
     7201 gcacgcctgc ccagatctcg cgcttcataa tatttacggg cctacggaaa acacgacttt
     7261 ttcaaccttt tttgaaataa agagagacta tgcggggccg attccgattg gaaaaccaat
     7321 cagcaatagc accgcttaca tcttagatac aaaaggacgt cttttgccaa taggcgttcc
     7381 cggcgagctt tgtgttggcg gtgatggggt cgctaaaggc tatttgaaca gagatgacat
     7441 gacaaatact gttttttctc ctcatccttt cttgcctgga gaaagaattt accgtaccgg
     7501 tgatttggca cgctggctgc ctgatggaaa cttagaatac atcagcagaa ttgacaggca
     7561 gatgaaaatt cgcggaaaac gaattgagcc cgccgaaata gaagcgcgcc tgttagaaat
     7621 ggaaggcgtt caagaagcag cagtgacatt gagagaaaaa gatggagagg cgcagctgta
     7681 cactcattac gtcggtgatc ataaaaaaac agatacggat tttcgcgccg atttggcgcg
     7741 tgtgcttcca gactatatga tcccgcagca ctgggtgcgt gtggagcgga tgccgcttac
     7801 cggaaacgga aaaatagacc gcagcgcgct gcctattcca gaaaataagc ctgccaaacg
     7861 acagaacatc atattgccaa gaaacttggt tgaagaagaa ttggcgaaca tttggaagca
     7921 agtcctcggt gttaacacaa tcagtattga tgatgacttc tttgctattg gcggacattc
     7981 actaaaagca ctgcatgtca tacatacact aaaacatcag cagaacattg acataccgat
     8041 tgatttcttg ttcgaacatc cgacaatcgc tcagcttgcc gaaaaacttt attctaaaca
     8101 gctgacagcg gcagatgaac agcatgtgat caaactgaac cagcacggcg cgcaaaatct
     8161 tttctgcttc ccgccgatat cgggatttgg catttatttt aaagaccttg ctttattact
     8221 gaatgagaag gcagccgtat acgggtttca ctttattgaa caagacaccc gcattgaaca
     8281 atatgttaat tgcatgacgg acatacagcc tgagggccca tacgttttat taggctactc
     8341 tgcaggcgga aacctggctt ttgaagtggc acaggctatg gagcgcaaag gattagaagt
     8401 cagcgacttc attatcgtgg acgcttatct aaaagaacag cctttgccta ttgataccgg
     8461 gaatgacgaa tctgcagcat atctgcctga agcagtcaga gaaaaggtga tgaagaaaaa
     8521 aagaaactat caagaatatt gggcacaatt gctgaatgaa gggcacatca aagcaagcat
     8581 tcatttcatc gaagctggaa ttcaaatcga aaccagcgag aatacaagct taacgaaatg
     8641 ggaaggcgcc tgtggaaact acagcgagta cacgggtttt ggcgctcata aagacatgct
     8701 ggaaggaaca tatgctgaaa agaatgctga catcatcctc gacattttag aaaagatcac
     8761 ttcaaatcaa gtaatactgc acaaacgata aagcggatta gcggacagag gccattctct
     8821 gtccgtcttt ctttttgtat caagaatgga taagggacac ttgggaatga taacatcatc
     8881 ctttttcttg gaggcttctc aatggaccgt ctttcttttc taacttttat catgctgatt
     8941 ctagccagtt acaggctgac acatttgatt gtatttgaca aaatcacaga atttatccga
     9001 aaacctttta tgaaaaagaa aaggattgtt gatcaaaacg ggcatgtaga tgaaaaaagc
     9061 gtgccggctt ctaactttgg atacatgctc aattgctact ggtgtgccgg tgtttggtgt
     9121 gccatcttga tcggacttgg ctatcttttt ttgcctcgta ttgcaatacc gctgatcttt
     9181 attttagcca ttgccggagc acaagcgatc cttgaaacgg ctgtcggtgt cggcgtaaaa
     9241 cttattgacg tgttaaaaag tttgcaaacc atgatgaatg ataaaaagtc ctaaaagcgg
     9301 cccacaacat gctttaggac ttttttcgtt tatttagtga gatagacatt ctgttaatca
     9361 cccttttata gcccgggaat accgtaatag cgagtgaaag tgatgtaatg ggggagaaga
     9421 aacagaatga aggtttgcca aaagtcgatt gtccgtttcc ttgtcagctt gatcatcgga
     9481 acgtttgtca tttccgttcc gtttatggcc aatgcgcagt ctgacagaga gctgagagcc
     9541 gtatggattg cttccgtatt aaatattgat tggccgtcca aaaaagggtt atctgtgaaa
     9601 gagcaaaaac aggagtatat caaactgctg gacgatgtgc aaaaaatggg aatgaatgcc
     9661 gttatcgttc agattaaacc gatggctgat gccttttatc cgtcagctta cgggccttgg
     9721 tcggaatact taaccggtgt ccaagggaag gacccgggct atgatcctct tgcatttata
     9781 attaaagaaa cccataaacg aaatttggaa tttcacgcgt ggtttaatcc ttaccgtatt
     9841 acaatgaatc atacagatct taataaattg tctgaggatc acccggcaag gaaacatcca
     9901 gattgggttg ccgcctatgg aaaccagctg tattatcatc caggcattcc agaagcgaga
     9961 gattttatcg tcaaaggcat tgaagaagtc gtaaaacatt atgatatcga tgctgttcat
    10021 atggatgatt atttttaccc ttataaaata gcgggacagg aatttcctga tcaagcacag
    10081 tacgaacaat acggaaaaga cgctttttct aatatcgatg actggcggcg ggacaatgtg
    10141 aaccagcttg tcaaacaaat caaccaaaca attaaagctg caaaaccgta tgtcaaattc
    10201 ggcatcagtc cctttggagt atggagaaac gccgcagatg acccgaccgg atcgaataca
    10261 aaagcaggcg tcagaaatta tgacgatcta tatgcagaca caaggcgttg gatccaagaa
    10321 ggcgacatcg attatattgc tccgcaaatt tattggagta tcggctttaa cgcagcggct
    10381 tacgacgtgc tggctgattg gtggagcaat gaagtcaaaa ataggcctgt tcacttatat
    10441 attggccagg cagcatataa aatcaataac aattttgatc cgccttggtc cgatcctgag
    10501 gaatatgtgc ggcaaatcac tttgaaccgc cagcttgaac tggtgaaagg aagcatgcat
    10561 ttcagcctca aggacctcaa caaaaatccg cttggcatca aagacagtct cagcaccgat
    10621 ctttacagca agccggcact ggttccgcaa atgccttggc ttgacaatac cgccccaaaa
    10681 aaaccgaagc ttacgaaagt caccgaagac aaaaacggca atcttctgca gattaaagat
    10741 cacccatcaa atcaaaaaac gaaagaaaca gcctattatg cgatatacag agccgaaggg
    10801 aaaaagcaga gaacattgct ggcaacgcaa agaaaaacac atgagcagca aaccttctta
    10861 gataacacgg cagatcctaa caagaaatat acgtattatg tcacttcagc agaccggctt
    10921 cataacgaaa gcaaggcttc caaacgaaca acaaaataag aaatgagaag gacggctttc
    10981 taagtcgtct ttttttaaaa gtgattttgg agacaggaaa cgatggtaaa ccgctgtagg
    11041 cggtgtttgg acattttcca ttattggaat ctgagaagct agtactaagt aaaatcgaag
    11101 agaaacacgt acaggacgtg ttttacgttt tcatttctag tctggttagg tgccacatta
    11161 ttttttgtgc tgttcgaaga tgctgtgttg actgatccgg ctgaagaagc ctttttgatg
    11221 aactttcttc tcttggaagc gggcaccgct cttgttttat gccttgtgtt ctttctctat
    11281 caaaaactcg atcaatcaca gttcgcggtg ataaagctag gtatatgggg atcagcggtc
    11341 ggtttattga ttgatacgat ttccctttgg aatcatcccc tcatcctccc ggctttatca
    11401 aagggccaag ttattgcgtt tgcgatatgg atggtatgcg cctactgcat gtatttgctc
    11461 attccgctga aattatcaca taaaaaatga ttcagtttta attttcagac ttttcttgtc
    11521 agggaatgat tatagaactc gcctaatagg atgttacaaa gatgtgaagg aggaaacgat
    11581 gtgaattttg agctgacaaa agaacaacaa atggtgcgtg aaatggtaaa agattttgcg
    11641 aaaaaagaaa ttgctcctca cgctgaacat gtagatcaaa caggcgagtt cccgatgcaa
    11701 acatttgaaa aaatgggtga actcggtctg atgggtattc catttccaga agaatatggc
    11761 ggatctggcg gtgatacgat ttcatatgcc ttagcggttg aagaagtcgg caaagcctgc
    11821 ggcagtactg gattaagcta tgctgcagcg gtctcgctag gcgcaagccc tctttactac
    11881 ttcggaacag aagagcaaaa acagacgcat ttgacgccgc tggcttcagg cacagcactc
    11941 ggatcattcg gcctgacgga gccaaatgcc ggctcagatg caggaggcac tcaaacaaaa
    12001 gcgatttcaa atggtgacga gtatgtaatc aacggcgaaa agtgctggat cactaatgca
    12061 agctacgcac gcacagttat tgtaaccgcc gtaacaggca aaaacaaaga cggaaaaaac
    12121 atcatctccg cattaatcgt gccaactgac acaccaggac ttacgattac gagcccgtac
    12181 gataaaatgg gcgtccgcgg ttcgaataca gcggaaattt tgcttgagga tgtaagagtg
    12241 cctgcggcca acttacttgg cgatccaaca aaagggttta aacagtttct atatacgctg
    12301 gacggagggc gaatctccat cgcttctctt gcagtcggca ttgcccaagc ggcccttgac
    12361 gcatcattgg catatgcgaa agaacgaaag cagtttggac agccgatttc ttcctttcaa
    12421 gcgattcaat ttaagcttgc tgacatggcg atggaaattg atctggcacg gcaaatggtg
    12481 ttaaaagccg cctggctgaa agaccataac cacccgttca ccaaagaagc ggcgtacgcc
    12541 aagctattcg catctgaaat ggcgacaaga gcttgcaatc aagccattca aatccatgga
    12601 ggttcaggct atatgaaaga gtatggggtg gaacggatgc tgcgggatgc aaaattaatg
    12661 gaaatcggtg aaggcacatc tgaaattcag cgtctcgtga tcgccagaca gcttttaaaa
    12721 taaaaatgta aacgctttcc tatcattaag aaaggaggaa caatgaatgg ctgaactcat
    12781 ccattccaca atcggcaggc tgctggaaca aacagctgat gcgtatcccg atcgagatgc
    12841 tgttgtgtat ccagaccgaa atatccgcta tacgtacgct caatttgaca gcctgtgccg
    12901 tcaaaccgct aaaggtctta tgcggatggg gattggaaaa ggagaccacg tcgccatatg
    12961 ggcttctaat atccctgaat ggcttgccgt ccagttcgca actgcgaaga tcggagccgt
    13021 gctcgtaacc gtcaatacca attatcaagc acacgagctg gactacttgt taaagcaatc
    13081 ggatgccgcc gcgcttatta tcatggattc atacaggggc acttcttatc cagacatcgt
    13141 aaacagttta attccagaac tgcaagaagc aaagcccggc caactgaaat ctgaacgcta
    13201 tcccttttta aaaacgctga tctatattgg caataaacgg ttggctggca tgtatcattg
    13261 ggacgagaca gagatattgg cgaaaacagt gacagatgct gagcttgaag agagaatgaa
    13321 cagcctggat aaagacaatg tgattaatat gcaatacaca tcaggaacga cagggtttcc
    13381 aaaaggcgtg atgctgaccc atttcaatgt catcaataac gctgctaata tcgctgaatg
    13441 tatggcttta acctctcaag accgcatgtg catcccggtt ccgttttttc actgctttgg
    13501 atgcgtcctt ggggttttgg catgtgtatc cgtcggggca gccatgatac ccgtgcaaga
    13561 atttgatccc gttaccgtcc ttaaaacggt agaaaaagag aaatgcacag cgctccatgg
    13621 tgtgcctacc atgtttatcg ccgagctgca tcatccggat tttgatgcat atgatctatc
    13681 gacgctccga acaggaatca tggccggctc tccctgtcca agtgaagtga tgaaagctgt
    13741 gattgaaagg atgggcatga aagacattac gatcgcctat ggacaaaccg aagcctcgcc
    13801 agtcattacg caaacgagag caaatgattc cttcataaga agagtcgaaa caaccggccg
    13861 cgccctgcca catactgagg tgaaaattgt agaacctggg acatgtcaag aagttcaaag
    13921 aggcatgcag ggagagctgt gcacccgtgg ctatcacgtc atgaaaggct attataaaga
    13981 caaagaagcg accagaaaag caatcaatca tgacggatgg ctgtttaccg gagatcttgc
    14041 tgtcatggat gaagacggat actgccgcat caccggaaga ttaaaagata tgctcatcag
    14101 aggcggcgag aacatttatc cgcgggaaat tgaagaattt ttataccggc atcccgctgt
    14161 tttagatgta caggtcgttg gtgtgcctga cgccaaattc ggggaggaag ctgcagcctg
    14221 gattaaactg aaagacggta aaagcgtttc acctgatgag cttaaagcct attgcaaagg
    14281 gaaaatcgcc cgccacaaaa ttccgcgtta tgttattttt acggatgact atccgatgac
    14341 ggcctcaggc aaaattcaaa aatataaact gcgagaaaaa acgattgaaa tgttcaacct
    14401 atcatcaagt caatgaggtg aaatcatgtt tacaaaagta ctgatcgcca accgcggaga
    14461 aattgcaatg agaattatcc gaacatgcag ccgtctcggc attaaaacgg ttgcggttta
    14521 ttcagaagcc gacaaggacg cgctccatac aaaagccgct acagaggctt atttgatcgg
    14581 agaatcgaga gtcagtgaaa gttatttaaa tatagagaga atcataaaga cggcgaaaaa
    14641 agcaaatgcc gacgcgatcc acccgggata tggattgtta tcagaaaaca gtcggttcgc
    14701 tgaacgctgc aagcaagaaa acatcgtgtt tatcggacct tcccctgata tcatcgcaaa
    14761 gatgggcagc aaaattgaag cgcgaaaagc aatggaggct gctggtgtcc ctgtggtgcc
    14821 gggcgtttct gaatccctcg gagatataga ggcagcctgc cgcaccgcag gtcaaatcgg
    14881 ctatcctgtc atgctgaaag cttcagcggg cggagggggc atcggaatgc agcgtgttga
    14941 aaatgaagaa gcattaaaaa aagcgtacga gggaaacaaa aagcgcgcag cagatttttt
    15001 tggtgacggg tcgatgtata tagaaaaagt tattgaacat gcgcgccaca tcgaggttca
    15061 gcttttggcc gatcaacacg gccatacagt acatctgttt gaacgtgatt gctctgttca
    15121 gaggcgccac caaaaagtca ttgaagaagc accgtctcca tttgtagacg atgaactaag
    15181 aatgaagatc gggcaaacag cggtaaaagc agcgaaggca atcggctata cgaacgcagg
    15241 caccatcgaa tttatagttg accagaagca aaatttttat ttcctcgaaa tgaatacgag
    15301 actgcaagtt gaacaccccg tgactgaaga aataacaggc ctggacttag ttgagcagca
    15361 gctgcggatt gctgcgggcc atacactcac attctcccaa aaagacatca aacggaacgg
    15421 gcatgcgata gaggttcgaa tatacgcgga agatcccaag accttcttcc cgtcaccagg
    15481 tacgatcact gcgttttcac ttcctgacca aaaaggagtc agacacgaat gtgcggtagc
    15541 aaaagacagc accgttaccc ctttttatga cccgatgatc gctaagatga ttgtcaaagg
    15601 ccaaaccaga acagaagcaa ttgaaaaact agagacagcg cttcgcgact atcgtgtaga
    15661 gggaatcaaa acaaatcttc cgcttctcat acaggctgcg gcaacaaagg catttaaaga
    15721 aggggatgtc acgactgact ttttgaaaca acacctataa aggaggcagt tgtcatgacg
    15781 gttagcatac aaatggcagg aaacctgtgg aaagtccacg tcaaagccgg cgaccaaatc
    15841 gaaaagggcc aggaggtagc cattttggaa tcgatgaaaa tggaaatccc gatcgttgca
    15901 gatataagcg gaatcgtaaa agaagtcaaa aaaaatgaag gcgactttgt aaatgaagga
    15961 gacgtactgc tcgaactgag cgattccact caataatttg gaggaagaac atgtcatatc
    16021 ctaaaaaagt gacaatcaaa gaagtcggcc cgcgtgacgg cttacaaaac gagcccgtat
    16081 ggatcgcaac agaggataaa ataacctgga tcaaccagct ttcccggaca gggctttcgt
    16141 atattgaaat cacatccttc gttcacccga aatggattcc ggcgcttcga gatgctatcg
    16201 acgtagcaaa aggcatcgac cgtttaaaag gggtaacgta cgcggcactt gtcccgaatc
    16261 aaagaggact ggagaatgca cttgaaggag gcattaacga ggcttgcgtt tttatgtccg
    16321 ccagcgagac gcacaacaga aaaaacatca ataaatccac ttctgaatcc cttcatatac
    16381 tcaaacaagt aaacaacgac gcacaaaaag caaacctcac aacaagagcc tacctctcga
    16441 ctgttttcgg ctgtccgtac gaaaaagatg tccccattga acaagtcatt cgcctttcag
    16501 aagctctatt tgaatttggg atttctgaac tttcgcttgg agatacgatt ggagcggcta
    16561 atcccgccca agtggaaact gtacttgaag ctcttttggc acgattcccg gctaatcaaa
    16621 ttgccttgca ttttcatgat acgagaggaa ccgctctggc caacatggtc acagcactcc
    16681 aaatgggcat cacggtgttc gacggctcgg caggcgggct tgggggatgc ccatatgcgc
    16741 caggttcatc aggaaacgcc gcaactgagg atatcgtgta catgcttgaa cagatggata
    16801 tcaaaacaaa tgtaaagcta gaaaaactgc tatctgcggc caaatggatt gaagaaaaaa
    16861 tgggcaaacc gctgccgagc agaaatttac aggtgtttaa atcatcttga taaaagggag
    16921 gacgcataca atgggagatt ctattctttt tactgttaaa aatgaacata ttgcgttgat
    16981 caccttaaac aggcctcagg cagcaaatgc tctttcagcg gaaatgctta gaaacctgca
    17041 aatgattatc caggaaattg aatttaactc aaacatccgt tgcgtcatcc tcacaggcac
    17101 cggtgaaaaa gcgttttgtg caggggcaga cctaaaggaa cggataaaac tgaaagaaga
    17161 tcaggttctg gaaagtgtat ctctcattca aagaacggcg gctttacttg atgccttgcc
    17221 gcagccggtc atagctgcga taaatggaag cgcattaggc ggcggactag aattggcatt
    17281 ggcatgcgac cttcgaatcg caactgaatc agctgtgctg ggacttccgg aaacagggtt
    17341 agctattatc ccgggcgctg gagggaccca aaggctgccc cggctgattg gcagaggaaa
    17401 agcaaaagaa ttcatttata caggcagacg cgtgaccgca cacgaagcaa aagaaatcgg
    17461 ccttgtagag catgtcaccg ctccttgtga ccttatgcca aaagcagagg aactggccgc
    17521 agccatttct gccaacgggc cgatcgctgt ccgtcaggct aaatttgcaa tcaataaagg
    17581 attggagaca gatctcgcta caggccttgc gattgaacaa aaagcgtatg aacaaaccat
    17641 cccgacaaaa gacaggagag aagggcttca ggcctttcaa gaaaaaagac gggccgtata
    17701 caagggaata taaaagggag gcaatgctca tggattatga aaaggaacga acagaacggg
    17761 ctgaacggat tcgaaaaggc ggagcggaaa agtatcatca aagcaatcgg gaaaaaggca
    17821 agctctttgt cagagagcgg ctttcccttc tctttgacga tgacattgag ctagaagacg
    17881 ctttttttgc ggaatgtatg tcagacgggc ttcccgctga tggagttgta accgctatcg
    17941 gcaaaatcgg cggccaaact gtttgcgtca tggcgaatga ttcaacagtg aaagcggggt
    18001 catggggagc aaaaacagtt gaaaaaatca tcagaattca agaaaccgcc gaaaaattaa
    18061 actgtccgct catttattta gtcgattcag caggcgcccg aattaccgac caaatcaatg
    18121 tctttccagg gagacgcggt gcaggaagaa ttttttacaa tcaagtcaaa ttatcgggac
    18181 gcattccgca aatctgtctg cttttcggac catctgcggc aggtggcgct tatattccgg
    18241 ccttctgtga tatcgtcgtt atggtagacg gtaacgcctc catgtattta ggctcgccaa
    18301 ggatggcgga aatggttatt ggcgaaaaag tgtctcttga agaaatgggt ggcgcccgta
    18361 tgcattgctc aatctccggc tgcggagata ttcttgcaga aactgaagaa gaagccatac
    18421 agctggcgcg ggcttatttg tcttactttc cggcaaattt tcaagaaaaa gcgcccattc
    18481 ataagaaacg cccgccaaaa cacttcgaca ctccgcttgc cgacgtcatt ccgcaaaatc
    18541 aaaacgcacc ttttgatatg catgagctga ttgagcgggt catagatgaa gactcatttt
    18601 ttgagatcaa agccttattt gcaccggaat tattgacggg cctcgcacga atccacggac
    18661 agcctgtcgg cattgttgca aaccagccga aggtaaaagg aggcgtctta ttccacgatt
    18721 cagcagacaa agcggctaag tttattacct tatgtgacgc ttttcatatc ccattgctgt
    18781 tcttagccga tatccccggt tttatgattg gcacaaaagt agaacaggct gggattatca
    18841 gacacggagc gaaaatgatt tctgcgatgt cggaggcaac tgttccaaaa ctctctgtca
    18901 ttgtccgaaa agcttacggg gctgggttgt atgcaatggc agggccggca tttgaaccgg
    18961 attgctgtct agcgctccca accgcccaaa tcgccgtcat gggccctgag gccgctgtaa
    19021 acgctgtcta cgctaaaaaa atcgccgagc tgccagaaga agagagagcc gcatttatca
    19081 gcagcaaacg ggaggaatac aaagaggaca tcaatatcta ccgtctggct tcagaaatga
    19141 tcattgatgc tgttatccca gccaattcgc tgcgtgatga gctggccaaa cggctcaagg
    19201 catacatgac aaaggaaatg acatttacca atcgaaagca tccggtttat ccagtgtaaa
    19261 agcaagaact taggagcgca aaaaaagcgc tcctttatat atttacaata acaacattat
    19321 gtcaactaat tacctttgca taaaacgctt tgttttttag aatagtaaat aaaggctgcc
    19381 gcacctctag cggcaattgt cagtttatca taaaaagggg cctacattat gtatcattta
    19441 tattcacata acgacttgga cggagtaggg tgcggaatcg tagcaaaatt agcgttcgga
    19501 aaagacgtag aggtccggta taactctgtc aacggcttaa acgcacaggt gcagtacttt
    19561 ttagaaaaag cgaaggagag caacagacag gacgcgttat tcatcaccga tctcgccgtc
    19621 aatgaagaaa acgaagagag attgaatgag tatgttcatg cagggggcaa agtgaagctc
    19681 attgaccatc ataaaacagc ccttcatttg aatgagcatg aatggggatt tgtcaaggtg
    19741 gaatacgatg atggaaggct cacatccgcg acatcgcttt tatatggcta tctcgttgaa
    19801 aatggcttca tgaaaccgac aaacgcctta gatcaattca cagagctcgt ccgccaatac
    19861 gatacatggg agtgggagcg gtacgatcaa aaacaggcga agcggcttaa tgatcttttc
    19921 tttttgctgt caatcgatga atttgaagaa aaaatgatcc agcgcctttc cacgcatgac
    19981 gaatttttct tcgatgattt tgaagaaaaa ctgcttgatt tagaagacga aaaaatcgag
    20041 cgctacctcc gcagaaagaa aagggaaatg gtacaaacct ttgttcacga acactgtgta
    20101 ggcatcgttc acgctgaatc gtaccattca gagctgggga acaggctagg gaaagataat
    20161 ccgcacctcg attacattgc gattttgagc atggggtcaa aacgagtcag tctccgcacc
    20221 attcatgatt acatcgatgt gtcagaaatc gccggccgat atggcggcgg agggcatgca
    20281 aaagcgtccg gctgttcaat aaccgatgaa gtatacgagt tgtttgtagc tgaagctttc
    20341 cgtattgatc ctgtacggcc ggatgccttc cgtaacatct ataatctaaa gggatctgcg
    20401 aatggatcat tatatgaaaa tcgcgcacaa atgagatttt ttcttttccc tttagacaac
    20461 gaatggaata ttcaaattaa cggagaaacc caagacgaaa cattcgcagc gtttgaagag
    20521 gcagaatggt ttattaagag aaattatgcc gcatcgctcg tgcgggatga agtgtttgtc
    20581 gcatttttag cggagaatct gaagctggca aatcaacatc ggaagtaaaa aaatatgcat
    20641 aggggagcgt cagtcacccc tatgcatatc tgctagctat cgtttaaata tggctgtacg
    20701 tttcttaatc acaaaataaa gggctatcac gacaacagcc aatatcataa tcggtgttgt
    20761 ataagtgcct gctatattct caacatcatc ccactggctt cctagctgta tgcctaaata
    20821 aacaaacaga atagaccatg gaatgatagc aagcacagtc agtaccacaa atttgagaaa
    20881 aggcattctg gcaatacctg ccggaatgga tatggcatgt ctgacaaccg gtataaaacg
    20941 agccgagaag acaactccgg cgccgtattt ctgaaaccag ttttccgaca tgtcgatatg
    21001 atgcttttta atcaataaat acttcccgta tttgtccaga aatggcctgc cgccatagcg
    21061 gccgatccag taaataaaga tctgggcaat ggtgcccccg ataacacccg caataattgc
    21121 gccaataaat ccaatcgtgc cctccgatac catatagccg ccataagcta atacaatctc
    21181 actcggaatg atttcaatca ttaacccaat cgcaataccc gcatatccca tgttcgtcag
    21241 ccatgttaaa atttcgctta tcaaactgcc cacattcttc acaacctgtc ctaatctttt
    21301 tcactattat atgactgatt gacgagcaag atggttacaa tttttttacc gcagcatttc
    21361 tttcgtttcc cgtttgatca catcttctaa ataggccaaa agctgagatc tcatttcggg
    21421 acgcattaag ccgatttcgg tgctcgcttt aaaacagccc agcttatcgc caatgtcata
    21481 tcgatttcct tccagcagcc gggcatggat cggctcctta cggcaaacct cacgaagcgc
    21541 atctgtcagc tgaatttcgt tgcccgcgcc tctgccaatt gtcttcaaaa cggagaagat
    21601 cgaagaattc agcacataac gtcccattac tgcgatttcc gaaggtgctt cttcaggaga
    21661 aggcttttcc actaaatcgt tcacttcata tacatgccct tgagaccctg atgtatttat
    21721 aataccatat ttgctgacat cctcagggag aactgactgt acaccgacaa cctctgtgcc
    21781 ataaacgtca tatacatcca ttaattgccg aagagccggt gtttcagaca ccataatatc
    21841 atcacctaag agaacagcaa aaggctcatc tccgataaaa tgctccgcac acagcaccgc
    21901 atggcctaat ccgagcggtt ctttctggcg gatgtaatga atgttggcca aatcggcaat
    21961 ctgctgcatt tccttaagtg tctccgtctt gcctttttcc cggagattga attccaattc
    22021 cgccgaccga tcaaaatgat cttcaatcga gcgtttgttt ctccctgtaa taatcagtat
    22081 atcttcaatt cctgactctg cggcctcttc tacaatatat tggattgctg gtttgtcgac
    22141 gattgggagc atttctttag gctgcgcctt tgtcgccggc agaaatctcg ttcctaaacc
    22201 cgctgcggga ataactgctt ttctcacttt ttttctcatt catcctcact cctgatcctg
    22261 tatgtttttc agtgaatctc caaataccca gattcggttt ccgataaaat tcatcatcat
    22321 tccgccgata gtggcggcga gcttactcac caaaagcgag cagccgcaat tttgaaacaa
    22381 ataaagcagc aaaaaggtga tccccgacgc ggcaatatta atcatgagaa aacgcacgat
    22441 ctctttcccg tcagccttac gtttcacaca aaacgtccaa ttccggttcc acacatagct
    22501 gttgacgata cctgcagtat aggagcagat ctgcgccggc agataagaga catgacaagc
    22561 ggtaagaaga aagaagacac caaaatctat cagcgtattg ccgacgccta cggtgcaaaa
    22621 acggcctaag gtctttattt tttctttcag cgtaacggac ctcccttcat aaaagatgcg
    22681 agtggcagtc atatttgttg atatggatta ctatagcgga cagtgttgaa taaacaatta
    22741 ataaaatatg aacaaaacat gaaaaaagcg ggtataccgc tcaatagttt ttatactctt
    22801 taaaaagcag cggcatgaac ggctgatttt tcgaaaacgc tcattacaaa aagatgaaaa
    22861 aatatgacat atttcgcagg ggaagagggc gaaatgataa cgaaaggtct tgcaaagaag
    22921 agaacaatac ttcaatagat tgagtggttt taagccttga ttccctatca gcagagatga
    22981 tgtctattat gtcaataatc gagggaacag tctaagcgaa gaagagtcgg taacagccgt
    23041 atatgtagcc ccatctaaac aatgaataaa tgtatccagt tcctttgtag aatcgaacac
    23101 gaattcctcc aaaagtattc tatacactat ttttttaata aggtaggatg ttagataaag
    23161 ggattttttg aataaatata catacctgct caagcgttat aggggacttg aacaattcgc
    23221 cattttattt tctggacaat gaccgttagg aatgggggaa cttttctaga ttgatcttga
    23281 agaaacaagt ggtgcagtct tcatgacctg ttgttaacaa atttcaaaag aacccttcat
    23341 tttaaggaaa aaggaggctg ttaagtgatg aggaaaaagt gtagcgtatg tttatttgtt
    23401 tttgctttac tattgagctg tttatctgga aagtctgcgt atgctgccac cagtagtaca
    23461 attgcaaaac atgtagggaa ttcaaacccg cttatcgacc atcatttggg cgcagatccg
    23521 attgcgctga cctataacgg gagagtctat atttatatgt caagtgatga ctatgaatat
    23581 aatagcaacg gaacgattaa agataattca tttgccaatt tgaataaagt attcgtcatt
    23641 tcttcagcgg atatggtgaa ctggacagac cacggagcca ttccggtagc aggtgccaat
    23701 ggagctaatg gtggccgtgg gatagcaaaa tgggcagggg cgtcatgggc accgtcaatc
    23761 gcagtaaaaa aaatcaatgg caaggataaa ttcttccttt atttcgcaaa cagcggcgga
    23821 ggtatcgggg ttctcaccgc agacagcccg attggtccat ggaccgatcc aatcggaaaa
    23881 ccgctcgtaa cgccaagtac gccaggaatg tctggtgttg tatggctttt tgatccggca
    23941 gtatttgtag atgatgacgg caccggttac ctgtatgccg ggggaggcgt tcctggcggt
    24001 tcaaatccaa cgcagggaca atgggccaat cctaaaacgg ctagagtcat aaaattgggg
    24061 cctgatatga cgagtgttgt tggaagtgca tctacaattg atgcgccttt catgtttgaa
    24121 gattcgggat tgcacaagta taacggaaca tattattact cctattgcat taatttcggc
    24181 ggcacgcacc cggccgataa acccccgggt gagatcggct acatgaccag ttcaaatccc
    24241 atgggtccct ttacatatag agggcacttc ctgaaaaatc cgggtgcatt tttcggaggt
    24301 ggcggaaaca accatcatgc tgttttcaat tttaaaaacg agtggtatgt ggtgtaccat
    24361 gcgcaaactg tcagttccgc tctgttcggg gccggcaaag gataccgttc tccacatatt
    24421 aataagctgg tgcataaccc agatggatcc atccaagagg tagcagcaaa ttatgcaggt
    24481 gtaacacaac tttccaattt gaatccttat aaccgggtag aagctgaaac gtttgcttgg
    24541 aatggacgca ttttgacaga gaagtccaca gcacccggcg ggccagtaaa taatcagcat
    24601 gtaacaagca ttcaaaatgg agactggatt gctgtaggaa atgcagactt cggagcggtc
    24661 ggtgccaggt catttaaagc aaatgtagca tccacttcag gcgggaaaat agaagtgcgc
    24721 ctcgacagtg cagacggtaa gcttgttgga actctgaatg taccttcaac aggcggagcg
    24781 caaacgtgga gagaaataga aactgcagta agcggggcaa ccggtgtgca caaagtattc
    24841 tttgtattta ccggaacagg tacaggaaac ttgtttaatt ttgattactg gcagtttacg
    24901 caaagatagt actcgtaatg ggaccgctta aaaacgaggc gggtgaagta cgggcgggca
    24961 ccggaacagc ccgccattat ggatatgcca tgcagatttt ttaataccgt aaaagacaca
    25021 tgacgaagga gaggaataaa tgattccacg cataaaaaaa acaatttgtg tactattagt
    25081 atgtttcact atgctgtcag tcatgttagg gccaggcgct actgaagttt tggcagcaag
    25141 tgatgtaaca gttaatgtat ctgcagagaa acaagtgatt cgcggttttg gagggatgaa
    25201 tcatcccgct tgggctgggg atcttacagc agctcaaaga gaaactgctt ttggcaatgg
    25261 acagaaccag ttaggatttt caatcttaag aattcatgta gatgaaaatc gaaataattg
    25321 gtataaagag gtggagactg caaagagtgc ggtcaaacat ggagcaattg tttttgcttc
    25381 tccttggaat cctccaagtg atatggttga gacctttaat cgtaatggtg acacatcggc
    25441 taaacggctg aaatacaaca agtacgcagc atacgcgcag catcttaacg attttgttac
    25501 cttcatgaag aataatggtg tgaatcttta cgcgatttcg gtacaaaacg agcctgatta
    25561 cgctcacgag tggacgtggt ggacgccgca agaaatactt cgctttatga gagaaaacgc
    25621 cggatcgatc aatgcccgcg tcattgcgcc tgagtcattt caatacttga agaatttgtc
    25681 ggacccgatt ttgaacgatc cgcaggctct tgccaatatg gatattctcg gaacccacct
    25741 gtacggcacc caggtcagcc aattccctta tcctcttttc aaacaaaaag gagcggggaa
    25801 ggacctttgg atgacggaag tatactatcc aaacagtgat aacaactcgg cggatcgatg
    25861 gcccgaggca ttggatgttt cacaacatat tcacaatgcg atggtagagg gggactttca
    25921 agcttatgta tggtggtaca tccgaagatc atatggacct atgaaagaag atggtacgat
    25981 cagcaaacgc ggctacaata tggctcattt ctcaaagttt gtgcgtcccg gctatgtaag
    26041 aattgatgca acgaaaaacc ctaatgcgaa cgtttacgtg tcagcctata aaggtgacaa
    26101 caaggtcgtt attgttgcta tcaataaaag caacacagga gtcaaccaaa actttgtttt
    26161 gcagaatgga tctgcttcaa acgtatctag atggatcacg agcagcagca gcaatctaca
    26221 acctggaacg aatctcactg tatcaggcaa tcatttttgg gctcatcttc cagctcaaag
    26281 cgtgacaaca tttgttgtaa atcgttaaga gcacaaagac acacataaat aatagagtgt
    26341 ctgaattggc gattttccga ttgggaaatc gcttttttat tttgttgctg aattacagga
    26401 agaagaaagg atgtacataa aaacagcaaa gctttattct tcatcttttc tagtttacat
    26461 aatatatatt ctaggaagta aacaaaataa ataaatttct gtctcaatat caaagtatac
    26521 ttaagttagt gagacagaaa ttgaaatttt actgctgaat gacaaatcaa aaaaatggtg
    26581 ttgtcaatcc ataataaacg gcttctaaat cttccagcgt catatcgcca tatgcgcatt
    26641 tgataacaga atcagcaaac acatcatagt cataatctgt agaaaatcct tgctgcagct
    26701 gtttttcgta aacttcgatc tgatcttttt gatgctggat gtctttttcc ttacctggat
    26761 agtcgggacc atttatcata ttactcattt ttttatacag caccatatac tgtttcagta
    26821 tttcatccac aacgcaaacc tcctattaga tgataaaaac ggacatcgtt actgatgtcc
    26881 gccaaaaaaa gcttaactaa tttggttctg ttccccaaat cagttttcct tgatcatata
    26941 atgtgatttt tttcgttgtt ttaaacgtat ttgatttgaa aaaggaataa tcgccgcttt
    27001 gtgcataatt gctccagtca tcattgtgaa gacggagctg aatattccct gtgcttgctc
    27061 ccggtgccaa cgttccgttt ttaaatccaa gttccagata ggtatctgca ccttgctttg
    27121 gtttatgcaa cgtcacaaac ttgtgtgtca cattgccgca tccaatctgc gcgtagtcac
    27181 agtcaaagtt ttggcctttg tttttcgctt tataccagta acgggcagtg acatctttta
    27241 aatcaaccgt ggtattgccg ttatttttta tttgaagctg cggacggatt tggttgctgt
    27301 tcatactccc atcccctgct ctgtactgta cagaaatacc attttcctgt gtgggtttat
    27361 cttttgatgg cgtttcagga atgtccttcg tcgaatcttt ggtgccgaga atgttttctc
    27421 taacgaatgt tcctgaagca gataaatctg acaaccgcca gccgcctgtt ttagatgccc
    27481 ccggctttaa agctgaggat gattcctgct tatcagaaag attccagttc acccagctga
    27541 tggtcttgct gtcaagatat ttcagccatt ccctcgattg atcaaggaat acaccgccat
    27601 tgccagacgc gtcgcttgtt ccccactctg tcacaaaaat aggtgctcct ttgctgagtg
    27661 catagtttgc tttatcccgt aaaaattggc cgtgtgtgcc ggcataaaaa tgaagtgcgt
    27721 acataacgtt tgcatctttt agctggtcat cggcagcatc attcacatcc tggctccatg
    27781 taccggttcc gacaatgatg atgttgtctg gatcattttt gcggataact gaaatcactt
    27841 cttccgcata tggtttaata tcacgcttcc agttcacatc accgtttggt tcgtttgcaa
    27901 tttcataaat gacgtttggc gtgtttccgt aaaggcttga catttccttg aagaattctt
    27961 ttgccttctc tttattttgg tttggattac cgtcatttaa gatatgccag tcaatgatga
    28021 catatatccc aagctctttt gccgcttcaa ccgcttcttt tactttattt ttcacggacg
    28081 ggttgtcaat ataaccgcca tctgccgtat acatcgctgc acggaaaacg gtgatacccc
    28141 aatcatctct cagccatttt aagctgtctt tattgacata ttctccatac cattgcaatc
    28201 cgtgtgaact gatccccttc agctgtaccg ctttaccgtc tcggttaacg agctgtgtac
    28261 cttttatgct aagctggcca ttcttggcta ctggcgtttt tgtccctgct gctgatgccg
    28321 gcgaagctat catgccgccc attgtcaata acgtaatcaa taaacacgta ataaaaatag
    28381 agattgaccg tttcatatct gatcttttcc tccttcgcat cattttggct ctacacttct
    28441 tatgagcacg aactcatagt aaaaatcttt ctcatgattg tctatcaacc taatttcttg
    28501 tttttgggag gtttaaaagc ctgtcaattt gctctacctc caatgaataa gacacacatg
    28561 acatatatag aacaaagaaa accggactga attgggactt tacacgtcat ttttcaatcg
    28621 agtcgaaaaa ttaaatttat ttccaataat gaaaaagctg cattcaacta ttgaatgcag
    28681 ctttgtttta tatttaaatt atgcttcttg tttctcatct tcccatgttt cagcgttttt
    28741 cagccctggg atgtttttcg ctttaaacac aggatcaagt ccttgcttac g
//
