LOCUS       NZ_NJRD01000003        20747 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain 20-3 20-3_R1_(paired)_contig_3, whole
            genome shotgun sequence.
ACCESSION   NZ_NJRD01000003
VERSION     NZ_NJRD01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1055472)
  AUTHORS   Cui,Y.
  TITLE     Improper usage of probiotics constitutes a potential risk of public
            health
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1055472)
  AUTHORS   Cui,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JUN-2017) Beijing Advanced Innovation Center for Food
            Nutrition and Human Health, College of Veterinary Medicine, China
            Agricultural University, Yuanmingyuan West Road, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 9.5.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_010578135.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:42:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,274
            CDSs (total)                      :: 4,198
            Genes (coding)                    :: 4,064
            CDSs (with protein)               :: 4,064
            Genes (RNA)                       :: 76
            rRNAs                             :: 3, 1 (5S, 16S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 1 (5S, 16S)
            tRNAs                             :: 67
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 80 of 134
            Pseudo Genes (incomplete)         :: 67 of 134
            Pseudo Genes (internal stop)      :: 22 of 134
            Pseudo Genes (multiple problems)  :: 31 of 134
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 424982
            Orig. end                         :: 445729
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NJRD01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20747
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="3"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20747
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10747](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10747)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(422..1354)
                     /gene="hprK"
                     /locus_tag="CE053_RS07845"
     CDS             complement(422..1354)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hprK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391380.1"
                     /locus_tag="CE053_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="WP_003228097.1"
                     /transl_table=11
                     /translation="MAKVRTKDVMEQFNLELISGEEGINRPITMSDLSRPGIEIAGYFT
                     YYPRERVQLLGKTELSFFEQLPEEEKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEK
                     NGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETA
                     LELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRS
                     NKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMN
                     FRLKRMGLNAAEQFTNKLADVIEDGEQEE"
     misc_feature    1466..1481
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            1536..2726
                     /gene="nagA"
                     /locus_tag="CE053_RS07850"
     CDS             1536..2726
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391381.1"
                     /locus_tag="CE053_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_021480694.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.1e-42, bitscore:
                     142.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESLLIKDIAIVTENEVIKNGYVGINDGKISTVSTERPKESYSK
                     EIQAPANSVLLPGMIDIHIHGGYGADTMDASFSALDIMSSRLPEEGTTSFLATTITQEH
                     GNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVALFKK
                     WQQEAGGLIKIVTLAPEEDQHFELIRHLKEESIIASMGHTDADSAMLSDAAKAGASHMT
                     HLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIHSHPLAAKLAFLAKGSSKLILITD
                     SMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTLAGSILKMNEGARHMREFTNCSWTDIA
                     NITSANAAKQLGIFDRKGSVTVGKDADLVIVSSDCEVILTICRGNIAFISKEADQI"
     gene            2723..3451
                     /gene="nagB"
                     /locus_tag="CE053_RS07855"
     CDS             2723..3451
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391382.1"
                     /locus_tag="CE053_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_085185633.1"
                     /transl_table=11
                     /translation="MKVIECQTYEELSQKAARITADTIKEKPDAVLGLATGSTPEGTYR
                     ELIRLHQTENLSFQNVTTVNLDEYARLSSNDPNSYHFYMNDRLFQHIDSKPSRHFIPNG
                     NADDLEAECRRYEQLVESLGGTDIQLLGIGRNGHIGFNEPGTSFKSQTHVVTLNEQTRQ
                     VNARYFPSIDSVPKKALTMGIQTILSSKRILLLISGKSKAEAVRKLLEGNISEDFPASA
                     LHLHSDVTVLIDREAASLRP"
     gene            3469..4200
                     /gene="nagR"
                     /gene_synonym="yvoA"
                     /locus_tag="CE053_RS07860"
     CDS             3469..4200
                     /codon_start=1
                     /gene="nagR"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="yvoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391383.1"
                     /locus_tag="CE053_RS07860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylglucosamine utilization transcriptional
                     regulator NagR"
                     /protein_id="WP_014478108.1"
                     /transl_table=11
                     /translation="MNINKQSPIPIYYQIMEQLKTQIKSGELQPDMPLPSEREYAEQFG
                     ISRMTVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRL
                     IDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHIPFELAGELNESHFQ
                     SSIYDHIERYNSIPISRAKQELEPSAATTEEANILGIQKGAPVLLIKRTTYLQNGTAFE
                     HAKSVYRGDRYTFVHYMDRLS"
     gene            complement(4220..8089)
                     /gene="yvnB"
                     /locus_tag="CE053_RS07865"
     CDS             complement(4220..8089)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yvnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391384.1"
                     /locus_tag="CE053_RS07865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_044052448.1"
                     /transl_table=11
                     /translation="MRKYTVIASILLSFLSVLSGGHHESKAFPVVQQELFQTPHYIPLL
                     ENPPQIDVKAEMRSNLMIEAQVRDNSYQAFSAFLFYKQSNELGYKMVPMDPTPGAVRKF
                     LAQIPKRLIWNSELEYYIVMSNGKQRVESETKKLKLEGYQADLAHIPELLITELAVDTK
                     NIGRADGYEFIEIFNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPDERILIPSGETFVV
                     WLKPAGHPELTSADFNRYYQTQLKEGKNLAVIDETEGMANTRPRAVVISTNTGKDISVA
                     HYRKHALRRLSSVLYKYPLNGTAELLNISIGEKNPSPGTVLQAQVPDQKRKIKLDKEKP
                     VIEDLTDRKPVRPAESIELRADIRDRSLVKTAAFYYRTDENKPFKRILAEKDRNDNLYH
                     YIVYSPELIGKDQLEYYVAAGDGINEARTPVKMIDIKQTSKAHGLRLNIENRDTLSGTQ
                     FLKATTEGRADRIKLWIDGRKQVTEPAMEKEVYFAFDTRKTNLYFKNAVTMEGKVLKVF
                     DDTTNKYRTYSVPLPETLLRKGKQLQRITIRSGSKVSPFDTAENRDDFLVKNARLVLSD
                     GTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLEWDTSKLSEGAHHIQA
                     SDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSRIEEAEASLDGESI
                     TLPYHTSSSDLLPGKHSLKVTATDLAGNKTVIERIFKTEREHPDQPEVIDSEADTHKAK
                     ISVRVKDPTNDAMDVGFYRGFQYTARNHVKIFKHASLTEPPKSFVPERETPFTNKELER
                     VSAADGKTVSTENKELFPYHRFEVTVDPSIDENDLAEAVWKGSSLPGRKVTMYAWNYRT
                     NEWQPVDSFVAKDDKPFTLKASVIAADFVRESKMNVIVQDEIPPAKDMYTFVWMSDTQY
                     YAESYPHIFDKQTEWIKDNQKQLNIKYVFHTGDIVDDSADIRQWKNADRSMSVLDKSGI
                     PYGVLAGNHDVGHKDGSYRAFGKYFGSDRFDKKLHYGGSYKNNRGHYDLISSNGNDYIM
                     LYMGWGITDEDIAWMNQVLKKHPDRMAILAFHEYLLVSGNRSPIGEKIFKEIVKPNPNV
                     VMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQGGPEGGQGYLRLLQFDQANDM
                     VHVSTYSPYVKDKNYYDTDTYGNKDEFSLSLDLKPRIKKVETDYFECNVYTNEELGKRE
                     QVKSGDTAEFRWDHLEPQSVYYWYIIVEDSFNGKTKSPIWKFKTKKETYRPAPDQFDFR
                     HVSNP"
     gene            8254..8727
                     /gene="pchA"
                     /locus_tag="CE053_RS07870"
     CDS             8254..8727
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pchA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391385.1"
                     /locus_tag="CE053_RS07870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_085185631.1"
                     /transl_table=11
                     /translation="MDNSIHDELFQAIQQFALKRDKRVWQKVQIPSIGISSQHHDHLKK
                     DWTLTQLHIVSCIHTSQNVNNSFLASRLHISKAAVSKAIQALLKHNIITVTKKPGNKKE
                     IFYTLTESGKELAGLHERLHQKAKEQYKQLFNEFSIDDLKTVTAFLNLWIKYM"
     gene            complement(8768..9985)
                     /gene="cypX"
                     /locus_tag="CE053_RS07875"
     CDS             complement(8768..9985)
                     /EC_number="1.14.15.13"
                     /codon_start=1
                     /gene="cypX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391386.1"
                     /locus_tag="CE053_RS07875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pulcherriminic acid synthase"
                     /protein_id="WP_017695292.1"
                     /sec_met_domain="p450 (E-value: 1.6e-36, bitscore: 122.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSIKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISR
                     YHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFIGDALDHL
                     SPLIKQNAENLLAPYLERGKIDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVAD
                     FITSISQSPEARAHSLWCSEQLSQYLMPVIKERRVNPGSDLISILCTSEYEGMALSDKD
                     ILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPPVQ
                     LIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHREDLGIKSAFSGA
                     ARHLAFGSGIHNCVGAAFAKNEIEIVANIVLDKMRNIRLEEDFCYAESGLYTRGPVSLL
                     VAFDGA"
     gene            complement(10001..10747)
                     /gene="pchC"
                     /locus_tag="CE053_RS07880"
     CDS             complement(10001..10747)
                     /EC_number="2.3.2.22"
                     /codon_start=1
                     /gene="pchC"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391387.1"
                     /locus_tag="CE053_RS07880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclo(L-leucyl-L-leucyl) synthase"
                     /protein_id="WP_003242712.1"
                     /sec_met_domain="CDPS (E-value: 3.1e-83, bitscore: 274.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGMVTERRSVHFIAEALTENCREIFERRRHVLVGISPFNSRFSE
                     DYIYRLIGWAKAQFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERAL
                     VAHGGDPKAIHTFSDFIDNKAYQLLRQEVEHAFFEQPHFRHACLDMSREAIIGRARGVS
                     LMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHEFSIC
                     MRPNQGYLIVQEMAQMLSEKRITSEG"
     gene            11173..11682
                     /gene="pchR"
                     /locus_tag="CE053_RS07885"
     CDS             11173..11682
                     /codon_start=1
                     /gene="pchR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391388.1"
                     /locus_tag="CE053_RS07885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pulcherriminic acid biosynthesis transcriptional
                     regulator PchR"
                     /protein_id="WP_029318331.1"
                     /transl_table=11
                     /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVIDIPK
                     NMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVY
                     FKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQTDGT
                     PDKPVK"
     gene            11703..12914
                     /gene="pchE"
                     /locus_tag="CE053_RS07890"
     CDS             11703..12914
                     /codon_start=1
                     /gene="pchE"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391389.1"
                     /locus_tag="CE053_RS07890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_003228068.1"
                     /transl_table=11
                     /translation="MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTA
                     MVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLITGILATAAASIGCAVTTDFTLFLIF
                     RMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGAAGY
                     EGIFWILAAISIVLLVTNSITFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSF
                     VLFFIYFAVIVYLPILLTEHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLF
                     IGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAI
                     GMFNFIRYTGMAAGPMVSAYLLTMMPSAMSFSLLGLGFAALSFCLLPPMFSPQKRTKQK
                     KHHM"
     gene            complement(12943..13302)
                     /gene="yvlD"
                     /locus_tag="CE053_RS07895"
     CDS             complement(12943..13302)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yvlD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391390.1"
                     /locus_tag="CE053_RS07895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phage holin family protein"
                     /protein_id="WP_003228066.1"
                     /transl_table=11
                     /translation="MVKWAVSILVNALLLIVIDGYIDSIHISSIGAAIIASLILSILNV
                     LIKPLLIIFTLPVTMVTLGLFLFVINAITLMMTASIMGDSFQIDGFGTAIWASVILSVF
                     HLLIQKGILEPLRKK"
     gene            complement(13304..13501)
                     /gene="yvlC"
                     /locus_tag="CE053_RS07900"
     CDS             complement(13304..13501)
                     /codon_start=1
                     /gene="yvlC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391391.1"
                     /locus_tag="CE053_RS07900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PspC domain-containing protein"
                     /protein_id="WP_003228065.1"
                     /transl_table=11
                     /translation="MNKLYRSEKNKKIAGVIGGLAEYFNWDASLLRVITVILAIMTSVL
                     PVLLIYIIWIFIVPSERDMK"
     gene            complement(13506..14603)
                     /gene="yvlB"
                     /locus_tag="CE053_RS07905"
     CDS             complement(13506..14603)
                     /codon_start=1
                     /gene="yvlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391392.1"
                     /locus_tag="CE053_RS07905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4097 domain-containing protein"
                     /protein_id="WP_014481027.1"
                     /transl_table=11
                     /translation="MMQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALSV
                     HVHDEEEPFTTAKKESGKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQFKD
                     TDFSSVELQIANGSVNIVPWEDDDIRAECQAKVYRADSQDAARHAFLQHIECEIKGNKF
                     FIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSFSHLT
                     AEKAIAETANGQIKLASHSCGTIEAETINGLIDLRGKSESIDVQSFNGNIAINVTESDC
                     RSIYAKTTTGSVELAIPDDLAVKAELKSNLGSLSHELMDVEMLKEKNDTIQKEMMFTSN
                     QAHDQNITVFSESLTGAIKLKYSQR"
     gene            complement(14628..14954)
                     /gene="yvlA"
                     /locus_tag="CE053_RS07910"
     CDS             complement(14628..14954)
                     /codon_start=1
                     /gene="yvlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391393.1"
                     /locus_tag="CE053_RS07910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein YvlA"
                     /protein_id="WP_003244375.1"
                     /transl_table=11
                     /translation="MNRNQAIIASLCYFSVFIAPIIVPIVAYFVVNEKETKRHAIRSLI
                     SHIVPFVGWLFLFIALLGGAVAIDGDSLLPVFVIIGGAVIYFLVVIGIIIWNVIQGIKV
                     LRAA"
     gene            15172..15402
                     /locus_tag="CE053_RS07915"
     CDS             15172..15402
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391394.1"
                     /locus_tag="CE053_RS07915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003235419.1"
                     /transl_table=11
                     /translation="MEKDPSDYTVTQESVLKLIHEQKRMNREMIAELEQIHGPFPISHD
                     IQYIKVLLDSSNTHIVQDLMSVSKQLYKKTL"
     misc_feature    complement(15188..15203)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(15601..16515)
                     /gene="hag"
                     /locus_tag="CE053_RS07920"
     CDS             complement(15601..16515)
                     /codon_start=1
                     /gene="hag"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391416.1"
                     /locus_tag="CE053_RS07920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flagellin Hag"
                     /protein_id="WP_046160896.1"
                     /transl_table=11
                     /translation="MRINHNIAALNTLNRLSSNNSASSKNMEKLSSGLRINRAGDDAAG
                     LAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHSILQRVRELVVQAGNTGTQD
                     GTDLQAIQDEISSLVEEIGGGTNANGISDRTEFNGKKLLNGAFSEDSGKSLTFQIGANG
                     SQQLSVNIESMAATAIGALDDDGNLVADQTVAKIDVTKFADNAADTATVGFDAQLKTVD
                     DAINTVSKQRSKLGAVQNRLEHTINNLSASGENLTAAESRIRDVDMAKEMSEFTKNNIL
                     SQASQAMLAQANQQPQNVLQLLR"
     gene            complement(16853..19726)
                     /gene="uvrA"
                     /locus_tag="CE053_RS07925"
     CDS             complement(16853..19726)
                     /EC_number="3.1.25.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391396.1"
                     /locus_tag="CE053_RS07925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_003228057.1"
                     /transl_table=11
                     /translation="MAMDRIEVKGARAHNLKNIDVTIPRDQLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMDKPDVDAIEGLSPAISIDQKTTSRNPRSTVGTVT
                     EIYDYLRLLYARVGKPHCPEHGIEITSQTIEQMVDRILEYPERTKLQVLAPIVSGRKGA
                     HVKVLEQIRKQGYVRVRIDGEMAELSDDIELEKNKKHSIEVVIDRIVVKEGVAARLSDS
                     LETALRLGEGRVMIDVIGEEELMFSEHHACPHCGFSIGELEPRLFSFNSPFGACPTCDG
                     LGMKLEVDADLVIPNQDLSLKENAVAPWTPISSQYYPQLLEAVCTHYGIDMDVPVKDLP
                     KHQLDKVLYGSGDDLIYFRYENDFGQIREGEIQFEGVLRNIERRYKETGSDFIREQMEQ
                     YMSQKSCPTCKGYRLKKEALAVLIDGRHIGKITELSVADALAFFKDLTLSEKDMQIANL
                     ILREIVERLSFLDKVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSRLSGVLYILDEPSI
                     GLHQRDNDRLISALKNMRDLGNTLIVVEHDEDTMMAADYLIDIGPGAGIHGGQVISAGT
                     PEEVMEDPNSLTGSYLSGKKFIPLPPERRKPDGRYIEIKGASENNLKKVNAKFPLGTFT
                     AVTGVSGSGKSTLVNEILHKALAQKLHKAKAKPGSHKEIKGLDHLDKVIDIDQAPIGRT
                     PRSNPATYTGVFDDIRDVFAQTNEAKVRGYKKGRFSFNVKGGRCEACRGDGIIKIEMHF
                     LPDVYVPCEVCHGKRYNRETLEVTYKGKSISDVLDMTVEDALSFFENIPKIKRKLQTLY
                     DVGLGYITLGQPATTLSGGEAQRVKLASELHKRSTGRTLYILDEPTTGLHVDDIARLLV
                     VLQRLVDNGDTVLVIEHNLDIIKTADYIVDLGPEGGAGGGTIVASGTPEEITEVEESYT
                     GRYLKPVIERDKTRMKSLLKAKETATS"
ORIGIN
        1 gccgatcgcc tggccgagca aaatgctggg cgcggcaatg tccgcaagct tccagaacga
       61 aagttttttc actctcgaaa acacataacc cgttaaaatg gcgccgatta atccgccatg
      121 aatggcaatg ccgcccttcc aaatcttaat gatttctccc ggatgtgccg cataatagtc
      181 ccattcaaag gcaacgtaat aaattcgcgc gcaaataatc gcaatcggaa tggcaaacag
      241 gacaagatca ataaacgtat ctttctgcag cccccgtttt tcactttccc tcatcgcaat
      301 ccacagcccg agcaaagcgc cgagaccgat aatgattccg taccaatgga cggctaacgg
      361 ccccagctga aatgctatcg gattgagtgg ttctatcgct tcattcattt aacgccaact
      421 cctattcttc ttgttcaccg tcttcaatga cgtccgccag cttgttggtg aattgttcag
      481 cggcattcag ccccatccgc ttcaatctga agttcattgc tgccacttcg atgatgactg
      541 caagatttcg gcctggacgg acaggaatcg tcagttttgt aatttctgta tcaatgattt
      601 tcatggtctc ttcctcaagt ccgagccggt cgtattgctt gccctgctcc cagagttcaa
      661 gattcatgac aatcgtgatt cgtttattgc ttctgaccgc gccagcgcca aatagcgtca
      721 tcacgttgat aatgccaagg cccctgatct caagaaggtg ctcaattaat tccggagcgt
      781 ttcccacaag agtatcctga tcctcctgcc gtatttcaac gcaatcatcg gcaacaaggc
      841 gatgccctct tttcacaagc tccagcgctg tttcgctttt tccgacgccg ctctttcctg
      901 tgatcagcac gccgacacca tatatatcga caagaacacc atgaattgct gtggtaggcg
      961 ccagcctgct ctcaaggaag ttggttaaac ggcttgacag tcttgtcgtt ttcagcggcg
     1021 atctgaggac aggcacccca tttttctcgg aggcgtcaat cagctcctgc gggatgggca
     1081 tatctctaga aagaataata gctggtgtta catcagtgca cagagaatcc attcgctgtt
     1141 ttttctcctc ttcaggaagc tgttcaaaga aagaaagctc tgtttttccg agaagctgca
     1201 cgcgctctct cgggtaatat gtaaaatatc cggcaatttc aatgcctggt cttgataggt
     1261 cactcattgt aatcgggcgg ttaattcctt cttctccgct gattaattcc aaattgaact
     1321 gttccattac gtcttttgtg cgaacctttg ccacgatatg ttcctcctgt tccgggctgc
     1381 cccgagcttg ctcacaatac tttcatttta tcactttcag gcttgaacct aaaacagatt
     1441 ttataaaagg cgggaaaaca cctcagctgg tctagatcac tagtctgaaa aagagtaaaa
     1501 taaaggtatt caaattccag aaaggcggat catctatggc agagagtctt cttatcaaag
     1561 acattgcgat cgtgacagaa aatgaagtaa tcaaaaacgg ctatgtcgga atcaatgacg
     1621 gaaaaatcag cacagtctca acagaacggc ccaaggagtc atattcaaaa gaaattcaag
     1681 cacctgcgaa ttccgttttg cttcccggca tgattgacat tcatatccac ggcggctatg
     1741 gcgcagatac gatggatgca agcttttctg cgctcgacat catgtcgtca agacttcccg
     1801 aagaaggcac gacgagcttt ttagccacaa caattaccca ggaacatggg aacatttctc
     1861 aagctttggt gaacgcaaga gagtggaaag cggctgaaga gtcctcttta ttaggtgcag
     1921 aactgctcgg cattcattta gagggcccct ttgtttcacc taaaagagcc ggagcgcaac
     1981 caaaagagtg gattaggcct tcggatgttg cgcttttcaa aaagtggcag caggaggcgg
     2041 gcggactgat caaaattgtt acacttgcgc cggaggagga tcagcatttt gaactgatcc
     2101 gccatttgaa agaagaatcg attatcgcgt ccatggggca cacggatgcc gattccgcaa
     2161 tgctgtcgga tgccgcaaaa gcaggggcga gccatatgac ccatctgtac aacgcgatga
     2221 gcccgtttca tcaccgagaa cccggagtga tcggaacggc gctggcccat gatgggtttg
     2281 tgacagagct aatagccgat ggcatccact cccatccttt agcggctaag cttgcttttt
     2341 tggcgaaagg cagcagcaag ctcattttaa ttaccgattc catgagggca aaaggactga
     2401 aagacggcgt atatgagttc ggcggccaaa gtgtgacggt aagaggacga acagctcttc
     2461 tttcagacgg aacccttgcc ggttcgatcc tcaaaatgaa cgagggcgca cggcatatgc
     2521 gtgagtttac aaattgctct tggacggata tagctaatat aacttctgca aacgcggcca
     2581 aacagctggg catctttgac cgaaaaggca gtgtgactgt gggaaaagat gcagatttgg
     2641 tgattgtcag cagtgattgc gaggtgattc tcaccatttg ccgcggaaac attgcattta
     2701 tatccaagga ggctgaccag atatgaaagt aatagaatgt caaacgtatg aagagctaag
     2761 ccaaaaagca gccagaataa cggcagatac aatcaaagaa aaacctgatg ctgttctcgg
     2821 tttagcgacg ggcagcacac cggaaggcac gtatcgcgag ctgatccgcc tgcaccaaac
     2881 tgagaatctc tcatttcaaa acgtcactac agttaatttg gatgagtacg ccagactttc
     2941 aagcaatgac ccgaacagct atcacttcta tatgaatgac cgtttatttc agcatatcga
     3001 cagcaagcct agccggcatt ttattccgaa tggaaatgca gacgatttgg aagccgaatg
     3061 cagacggtat gaacagctag tcgagtccct cggcggcact gacattcagc ttctcggcat
     3121 tggccgaaac ggacacatcg ggtttaacga accgggaacg tctttcaagt cgcaaactca
     3181 tgttgtgaca ttaaatgagc aaacccgcca agtgaatgcc agatattttc cctccataga
     3241 cagcgtgccg aaaaaagcac tgacaatggg aattcaaacg atactctcaa gcaagcgcat
     3301 tctgctgctt atttctggaa aaagcaaagc ggaagctgtt cgtaagctgt tagaaggaaa
     3361 catcagcgaa gattttcccg catctgcttt gcacctgcat tccgatgtca cggttttgat
     3421 tgatcgtgaa gccgcgtcat taagaccttg aaaggaacat gctgacttat gaatatcaat
     3481 aaacaatcgc ctattccgat ttattatcag attatggagc aattaaaaac ccaaattaag
     3541 agcggagaac tgcagccgga tatgcctctt ccttctgagc gcgaatatgc cgaacaattc
     3601 gggatcagcc ggatgacagt tcgccaggcg ctttctaatt tagttaatga aggcttgctc
     3661 tatcgcctga aggggcgggg cacctttgtc agcaagccaa aaatggaaca agcacttcaa
     3721 gggctgacaa gctttaccga ggatatgaaa agccgcggga tgacaccggg cagcaggctc
     3781 attgattatc agcttattga ttcaactgag gagctcgcgg ctatattagg ctgcgggcac
     3841 ccctcctcta tccataaaat cactcgggtg cggctggcaa atgatattcc gatggcgatt
     3901 gagtcctcac atattccgtt tgagcttgcg ggtgaattga acgaatcaca ttttcagtcg
     3961 tcgatctatg atcatattga aaggtacaac agcataccga tttcccgtgc aaaacaggag
     4021 cttgagccaa gcgctgccac cacggaagaa gcgaacattc ttggtattca aaagggagcg
     4081 ccagtcctat taattaaacg aacaacatat ctgcagaacg gaactgcttt tgagcatgca
     4141 aaatccgtat acagaggcga ccgttataca tttgtccact atatggatcg tctttcataa
     4201 aaaaagcctc caaccctttt taaggattgg agacatggcg aaaatcaaac tggtctggtg
     4261 ccggacgata tgtttctttt ttcgtcttga acttccagat cggtgatttc gttttgccgt
     4321 taaaactgtc ttccactata atgtaccaat aataaacaga ctgcggttca aggtgatccc
     4381 agcggaattc agctgtatcc ccgctcttca cttgctcccg ttttccgagc tcttcattgg
     4441 tatatacatt acattcaaaa taatcggttt ccaccttttt gattcttggc ttcaaatcaa
     4501 gcgaaaggga aaattcatcc ttgttgccat aggtatccgt atcatagtaa ttcttatcct
     4561 ttacatacgg agaatacgtc gatacgtgca ccatgtcatt ggcctggtca aattgaagca
     4621 aacgcaaata cccttgaccg ccttctggcc cgccctgata atcggccagc atttgatgca
     4681 caagacgatc cggcttccca tcaccatcat catccagctc atctgttttt ctcatcgcac
     4741 tatgataatg cccgctcaat accatcacga cattcgggtt cggctttacg atttctttga
     4801 atattttctc tccgatcggg cttctgtttc cgctgaccag caaatactca tgaaaagcta
     4861 aaatggccat ccggtcaggg tgtttcttca gcacctgatt catccacgcg atgtcttcat
     4921 ccgtaatgcc ccatcccatg tacagcatga tataatcatt gccgttgcta gaaatcaggt
     4981 cataatgtcc gcggttattt ttataggaac cgccataatg caatttttta tcaaaacgat
     5041 cgctgccaaa atatttgcca aacgccctgt aggagccgtc cttatgtccg acatcgtgat
     5101 tgccggccag cacgccgtaa ggaattccgc tcttatccag aacggacatt gaccgatcag
     5161 cgtttttcca ctgtctgata tcggcggaat catctacaat atcacccgtg tggaacacat
     5221 atttgatatt gagctgcttt tgattatctt ttatccattc ggtctgttta tcaaaaatat
     5281 gcggatagct ttcggcgtaa tactgtgtat cagacatcca gacaaatgtg tacatatcct
     5341 tcgcaggagg aatttcatcc tgtacaatca cattcatttt cgactcccgt acaaaatcgg
     5401 cggcaatcac agacgctttc agcgtaaacg gtttgtcatc cttcgctacg aagctgtcaa
     5461 caggctgcca ttcgtttgtc cgataattcc aagcatacat cgtcaccttt ctccccggca
     5521 aagaactgcc cttccagacc gcttctgcca gatcattctc atcaattgat ggatcaaccg
     5581 tcacttcaaa gcgatgataa gggaaaagct ctttgttttc tgtcgatact gtttttccat
     5641 cagcagctga tacccgctcc aattctttat tcgtaaatgg ggtctccctt tccggcacaa
     5701 agcttttcgg cggttcagtc agtgacgcgt gcttaaatat tttcacatga ttgcgcgctg
     5761 tatattgaaa tcccctataa aaaccaacat ccatggcatc attcgtcgga tctttcaccc
     5821 gtacagaaat cttggcctta tgcgtgtcgg cttcgctgtc tataacctcc ggctggtccg
     5881 gatgctctcg ttcggtttta aatatcctct caatcactgt tttattgccc gcgagatccg
     5941 ttgctgtcac ttttagagaa tgttttcccg gcaaaaggtc agaagatgac gtatgatatg
     6001 ggagtgtaat gctttctcca tctaacgacg cctccgcttc ctcaattctg ctccatttat
     6061 catacatatc cgcctgcagg ataaggtttc ctttatacgt ttgcccctcg gtgatattcg
     6121 gctcaatgtg aggtcctgaa ttatctaccc gtacaaccag gctgacattt tccttgccgt
     6181 cgcttgcttg aatatggtga gcgccttcag aaagctttga tgtatcccac tccagcagct
     6241 gtgatgtaaa tagtccgtca ggcagattga actgaaattg ccagctttta tttgagcgct
     6301 gattatcgcc aataaagagt tccttctcag gggacaccct ctgatccctg atcaccgttc
     6361 catctgataa caccaatcgg gcgtttttga ctaagaagtc atcacggttt tcagcagtat
     6421 caaacggaga caccttcgaa cctgaacgta tcgtaatacg ctgcagctgc ttccctttcc
     6481 gaagcagtgt ctctggcaat ggaacagaat aggtgcggta tttatttgtt gtatcatcga
     6541 acaccttcag cactttgcct tccatcgtta ccgcgttttt aaaataaagg ttcgttttcc
     6601 tcgtatcgaa tgcaaaatat acttcttttt ccatcgcggg ctctgtcact tgttttctcc
     6661 cgtcaatcca tagcttaatg cggtcagctc gcccttctgt cgtggctttg agaaattgag
     6721 ttcccgacag cgtgtctctg ttttcaatat tcaaccgcag accgtgcgcc ttgcttgttt
     6781 gtttaatatc aatcattttg accggcgttc tcgcttcatt gatcccgtcc ccggccgcca
     6841 cataatactc tagttgatcc ttcccgatca attcaggcga atacacaata taatggtaga
     6901 gattatcgtt acggtctttt tcagcaagaa ttcgcttaaa cggtttgttc tcatccgtcc
     6961 ggtagtaaaa ggcagctgtt ttcactagac ttcggtcccg tatgtcagcc cgcagctcaa
     7021 tgctttcagc agggcggaca ggcttgcggt cagtcaaatc ctcaataacc ggcttttctt
     7081 tatcgagctt gattttccgt ttctggtcgg gcacctgtgc ctgtaatacg gttccgggag
     7141 acggattctt ttccccgatt gaaatgttca gaagttctgc tgttccgttc aacggatact
     7201 tataaagcac tgatgacagc cggcgcagcg catgtttccg ataatgcgca accgaaatgt
     7261 cctttcctgt attcgttgat atcacaacgg cccgcggcct cgtattggcc ataccctctg
     7321 tctcgtctat caccgcaaga ttttttcctt cttttagttg tgtctgataa taacgattga
     7381 aatccgctga cgtcaattct ggatgcccgg caggcttcag ccagacgaca aacgtttcgc
     7441 cggatggtat caagatcctt tcatcaggtc tccaaatcag atcggagtca ggcccttctt
     7501 ttgggtagcg gtaacggata tggtagtctt taaaatcaat cgttctgtca gtcgtattaa
     7561 aaatctcaat aaattcataa ccgtctgcgc gtcctatatt cttcgtatca accgccagct
     7621 ctgtgatcag aagctccgga atatgggcaa ggtcagcctg gtatccttca agcttcagtt
     7681 tcttcgtctc cgactcaacc cgctgcttcc cattcgacat cacaatgtaa tactcaagct
     7741 cgctgttcca aatcaaacgt ttcggaattt gtgccaaaaa cttgcggacc gctccggggg
     7801 tcgggtccat cggcaccatt ttgtagccca gctcattact ttgtttataa aaaagaaagg
     7861 cggaaaatgc ttgatacgaa ttatcgcgaa cttgagcctc aatcattaga ttgcttctca
     7921 tttcagcttt cacatcaatt tgaggaggat tttcaagcaa gggtatgtaa tgaggcgttt
     7981 gaaatagttc ctgctgtaca acaggaaaag ctttcgattc atgatggccg ccagacaaaa
     8041 cggaaagaaa agacagtaat atagaagcaa taaccgtgta tttcctcatc aaagcacctc
     8101 ccttttcatg tattttgcgt ctgaacaggg aagcttatga gttcattttt gtgcataaag
     8161 aacaaaaaaa cgtctgtctc ttgaaaattc cactattacc cagtaaacta aggatagtta
     8221 accagttaac aattaaatca gagaggcaaa ttgatggaca acagcattca tgatgaatta
     8281 tttcaagcta tacaacaatt cgcattaaaa agggataaac gcgtctggca aaaggtgcag
     8341 ataccatcca ttggcatatc ctcacaacat cacgatcacc tcaaaaaaga ctggactttg
     8401 acccagcttc acattgtttc ctgcatacat accagccaaa atgtgaacaa cagcttctta
     8461 gcatcccgct tacatatctc aaaagcagct gtttcaaaag caattcaagc tttgttgaaa
     8521 cataacatca ttacagtgac aaaaaagccg ggcaacaaaa aagaaatttt ttatacgtta
     8581 actgaaagcg gcaaagaact ggcggggtta catgaacggc ttcatcaaaa agcaaaggag
     8641 caatacaaac agctcttcaa tgaattttca attgatgatt taaaaacagt gactgcgttt
     8701 ttaaacttgt ggatcaaata tatgtaaaaa gagtctcacc cgcatgggag agacctttgg
     8761 aattctatta tgccccgtca aacgcaacga gaagtgaaac aggtccgcgt gtatacagac
     8821 cggactcagc ataacaaaaa tcttcctcta atctgatatt ccgcatctta tccagcacaa
     8881 tattagctac aatttcgatt tcgtttttgg caaaagctgc tcctacacag ttatgaatgc
     8941 cggatccgaa agcgagatgc cgggcggcgc cgctaaaagc gctcttgata ccaagatctt
     9001 cccgatgaat attaaacacg tcaggctgtt caaatgcttc agggtcccgg ttagccgcac
     9061 cgatcataca aaaaacaatc gtatcttttt tgatttccat accgccgacc actgtatctt
     9121 gggacagctg ccgcggaatc agctgaaccg gcggtttata acgcaatgtc tccgcaatgg
     9181 ctctcggaac taacgaacgg tcagccaaaa catcattcat ctgctcagga ttgttgagca
     9241 aatggtagat catcagtgcc agcgtcttat cagccggttc cgttgcggct aacagcacat
     9301 taagaatcag tgcgagtata tccttgtccg acagcgccat gccttcatat tcagaagtac
     9361 ataggatcga aattaaatct gatcccggat tgacgcgacg ttctttaatg accggcatca
     9421 agtattggga aagctgttcg ctgcaccata acgaatgtgc ccgcgcttca ggagattgag
     9481 agatactcgt gataaaatcg gcaactccgc tgtgccactc agagattttt tcatggtctc
     9541 ttttatccag cccgagcatg tccatcgtga cgcacaccgc gaatgtcttt ccaaaatcat
     9601 tgacgagatc aattttccct ctttcaagat aaggcgctaa caagttttct gcattttgtt
     9661 taatcaatgg agacagatga tccagtgcgt caccgataaa gcttctcact acaattcttc
     9721 ttttggcaga gtgttctttt ccatgcattt gggccagcac agggcctcgc atgactggtt
     9781 cggcacgctc aacaagtgat ttcgtcgtga agatatccgg atgctgaagg atatagcgga
     9841 catcatgata gcggctgata aaataactgt ctatcgactc ttcataatga accggatctt
     9901 cctcccgcag ttgtgaaaaa taagcatatg gattgttttg aaattgatca gaaagcacac
     9961 taaacaattt aatcgattgg ctcatgtttt actcccccta tcatccttca gatgtgatcc
    10021 gtttctcaga aagcatctgc gccatttcct gtacaatgag atacccttga ttcggccgca
    10081 tacaaataga aaattcatgg ttactgatct tctcacccag cttccacgga cgatgataag
    10141 caaggagtgt ctcttccacc tctaaaatat ccggagctcc gataaaaaac ggcagctcag
    10201 ctatgacata ttccacagcc aaattcagca tatcctcact gacttcttcc atcatcaaac
    10261 tgacgccccg cgcacgcccg attatcgctt cacgagacat gtccaaacaa gcatgtcgaa
    10321 aatgaggctg ctcaaaaaat gcatgttcaa cttcttgtct caacagctgg taggctttgt
    10381 tatcaataaa atcagaaaat gtatgaatcg ccttcggatc cccgccatga gccacaaggg
    10441 ctctttctgc aaatctcctg tttcgtgata cctctttcct tacttttcgt tcagcctttc
    10501 ctctcggagt tccaagcgct tctagaagat tagccgcctc atgccctgca agtaaaactg
    10561 aaacgctttt aaattgagct ttcgcccatc caattaatct gtaaatataa tcctctgaaa
    10621 acctgctgtt aaatgggctg atccccacca aaacatgcct gcgccgttca aatatttctc
    10681 tgcagttttc tgttaatgcc tcagcaataa aatgcacaga ccttctttcc gttaccattc
    10741 cggtcatctc attcacccct aaaacttatc ccgctttaag tcatcaccct caaatacaag
    10801 atggaatagc tagaacaact gaacaagacg aatggcaggc agcacttaaa gtttccaaat
    10861 gttttttaaa attttaataa ctatttccat ttcacatatc atgataaatg tttactagta
    10921 aacattagtc attttatccc ttttccttcc aaacgtcaat atgatctgtg cccaaatatt
    10981 tgaaaataaa tgtaaacatc acattttcca cacacttttt acacgcatat tcagcatgac
    11041 atatcaacaa atagtctaaa caccaacaat tgacaacgaa aacaagaaaa gataaaatga
    11101 aattgttcac cagtaaacga tttgttttat tgtttcatcg taaactatta ttcctaagaa
    11161 agaaggtagc ctatgtctga tttgacaaaa cagatgatat acgacatata cgtgagactg
    11221 ctgcacctta atgaacaaaa agcgaatact tcacttcagc aattttttaa ggaagccgca
    11281 gaagaggatg tgattgatat ccctaaaaac atgacaagca tacatgtcat tgactgtatc
    11341 ggccagcatg aacccattaa caatgcgggg attgccagaa aaatgaactt atcgaaagcg
    11401 aatgtaacga aaatcagcac aaaactgatc aaggaagaat tcattaacag ctatcagctg
    11461 acagataaca aaaaagaagt ttattttaaa ttaacccgta aaggcagacg gattttcgac
    11521 ttacatgaga aactgcataa aaaaaaggag ctggcttttt accaattcct cgattcattt
    11581 tcacaagaag aacaaaaggc tgtattgaag tttctagagc agttgacgtc aacacttgaa
    11641 gcagaacaaa ccgatgggac tccagacaaa cctgtaaagt aaacaaaaag gcggtgtaca
    11701 ctttggctca tacaaaatca aaggcagtat tgatcttata cactgtttgc ttcagtgcat
    11761 tttttgcatc tttaagccag aacatttatt cacctattct tccgatcatt aaagaatcat
    11821 tccatgtttc cacagctatg gtgaacctgt cagtctcagt ttttatgatt gtgacagcaa
    11881 taatgcaaat tatattagga gcgatcattg attttaaagg cgctcggatc gtcttgatta
    11941 ccggtattct ggcaacggca gcagccagca tcggctgtgc ggtgactact gactttacct
    12001 tgtttctgat attcagaatg atacaggcag ccggttccgc agcactgcct cttattgctg
    12061 ccacaacgat cggacagctg tttacaggaa atgaacgcgg gagtgcaatg ggaacgtatc
    12121 aaatgctcct gtctgtcgca ccggctattg ctccagttct aggaggattc ataggcggag
    12181 cagccggata cgaagggatt ttttggatac ttgcggccat ctctatcgtt ttgctggtga
    12241 caaacagcat cacctttcct aaagattctc caactgaatc tatgcagcaa gccaaaggca
    12301 atgtgttcgc tcattataaa tcaatattta caaatcgaac agggaacgtc attttgactt
    12361 taagttttgt tctctttttc atttattttg cagtaattgt ctacctccca atattgctga
    12421 cagagcatta ccatatagat gtgggtatag caggactgtt atatttgccg ctggcgctga
    12481 gcacgattgc aggtacgttt ctgtttaaaa gaatacaggc aaaaatcggg ctgcacacct
    12541 tgtttatcgg aagcaatgtg attgccgcct gcagcatcat tttatttgct gttacacatt
    12601 ccgtttctct cgttctcatg gctctgacgc tggcactgtt tggcatctcg atgggggtta
    12661 ttcctccctt gtactctaca atgattacta atgaatttga gcacaacaga gggagtgcaa
    12721 tcggaatgtt taactttatc cgatatacag gcatggcagc aggtccgatg gtatctgcct
    12781 acttgctcac aatgatgccg tctgccatgt cctttagcct cctaggcctt ggatttgccg
    12841 cattgagctt ttgccttctt ccgccaatgt tttcgccgca gaagcgcacg aaacaaaaaa
    12901 agcaccacat gtaaaaaagc tgcctttgcg ggcagctttt ttttattttt ttctaagcgg
    12961 ctctaaaatg cctttttgaa tcagcaaatg gaagaccgac aggataacgg atgcccatat
    13021 cgctgtgccg aagccgtcga tttgaaagct gtcacccata atggacgcgg tcatcataag
    13081 cgtgatggcg ttaatcacaa acaagaagag tccaagcgtc accatcgtga ctggcagtgt
    13141 aaagataatc aaaagcggtt taatcagcac gtttaagatc gataaaatga ggctggcgat
    13201 aatcgctgcc ccgatgctgc tgatatggat ggagtcaata tatccatcaa tgacgattaa
    13261 taacaatgca ttgactaaaa tgctgactgc ccattttacc atgtcatttc atatcccttt
    13321 ctgacgggac gataaaaatc caaatgatat aaatgagcaa aaccggcaag acacttgtca
    13381 taatggctaa gatgacagtt atgactctga ggagtgatgc gtcccaattg aaatattccg
    13441 cgagacctcc gataacaccg gcgattttct tatttttttc tgagcgataa agcttattca
    13501 ttcgatcacc tctgtgagta ctttagtttg atggcgcctg ttagtgattc tgagaagacg
    13561 gtgatgtttt gatcatgtgc ctgatttgaa gtgaacatca tttctttttg aatggtatca
    13621 tttttttcct tcagcatctc aacatccatt aattcatggg acagcgaacc aagattgctt
    13681 ttcagctctg ccttcactgc gagatcgtcc ggaatcgcaa gctccacact tccagtcgtt
    13741 gtttttgcat aaatggagcg gcagtctgat tctgttacgt taatcgcaat atttccgtta
    13801 aagctttgaa cgtcaatgga ttcgcttttc cctcggagat cgatcaatcc gttaatggtt
    13861 tccgcttcta tcgttccgca gctgtggctg gcgagcttaa tttgcccgtt ggccgtttca
    13921 gctatggctt tttcggctgt taagtgcgag aacgacagca cgccgtttgt cgttttcgct
    13981 gagaactctt ttacatgtaa atgttcccct ctgaccggac cgttaaacag cttcacccga
    14041 atcttatcat actccttctg aggaatatac aaagtgacat tcgttttcat cgtctttttc
    14101 tcagtacgga taaaaaactt atttcctttg atttcacatt caatatgctg aagaaatgcg
    14161 tgtctcgccg catcctggct gtcagcgcga tataccttcg cctggcattc cgctctgata
    14221 tcgtcatctt cccaagggac gatattcacg ctgccgttgg caatttgcag ctcaacactg
    14281 gaaaagtcag tatctttaaa ttgaaaaatg tgctgaacat catacgcatg gccaaagttt
    14341 aaatcaaggt caacttcctt gacctttttc acagcagaat caatccagtc aaacagcttg
    14401 gctcctaaag acggtttgcc gctttctttt tttgccgttg taaatggctc ttcctcgtca
    14461 tgaacgtgaa ctgagagcgc tgtgattttc tcttcttttt ccttgtagtc gctgtcaagc
    14521 ttttcaatca gtgtcaaagc ttcttgtgct gtaagctttc cttcctcaac aagcttaagg
    14581 attcgttcct tttcttgcat cattacgatc tcctccccat tgtctactta tgctgcacgc
    14641 aggaccttaa tgccctgaat cacattccaa atgataatgc caatgacaac caagaaataa
    14701 ataaccgctc ccccaatgat tacaaataca ggaagcaagc tgtctccatc aatcgcaacg
    14761 gctccgccaa gtaaagcaat aaaaaggaac agccagccga caaacggaac tatgtgagaa
    14821 ataagagagc gtatcgcatg gcgttttgtt tctttctcat ttacaacaaa ataagcgaca
    14881 atcggcacaa tgattggcgc aataaacaca ctgaaataac aaagtgatgc aataatagct
    14941 tgattacggt tcaattcatt ccacactcct attgtgaatt gtccatgaca aaagatcagg
    15001 gacgttttac ttatttatac gtttaaaatc tcttcaggtt tcaaattcat tctttagaca
    15061 tgctccgatt tacggaaatt ggattttaaa aagttttaga agtagaatct tccggctata
    15121 ccgattacaa tatgtaaaaa gcttacggca accaaggagg ctggacaagc aatggagaaa
    15181 gatcccagtg actatacagt aacacaagaa tcagtgttaa agctgattca tgaacaaaaa
    15241 agaatgaatc gtgaaatgat cgccgagctt gagcagattc acggaccctt cccgatctct
    15301 cacgatatcc aatatataaa agtgctgctc gacagcagca acacgcatat tgttcaagat
    15361 ttaatgagtg taagtaagca gctgtataag aagactttgt aattgcggaa aacatatcat
    15421 tcattataac tgaaacaaag ctaaaggtta gatgacaata tcttgccttt tttgttttga
    15481 aaaaacaagt gattccctgg ctgtcacaaa atgattgtaa caaaaaaagc ctgccggcac
    15541 atccagttaa tggactctgt cggcaagctg taactatcag aaagagatag cctttcaaaa
    15601 ttaacgtaac aattgaagca cgttttgcgg ctgttggttt gcttgagcaa gcatcgcttg
    15661 agaagcttga gaaagaatgt tgttctttgt gaactcgctc atttctttcg ccatgtcaac
    15721 gtcacggata cgagactcag cagcagtcag gttttcacca gaagcgctta agttgttgat
    15781 tgtgtgctct agacggtttt gtaccgcacc taattttgaa cgttgtttag aaacagtgtt
    15841 gatagcgtca tcaactgttt taagttgagc atcgaatcct acagttgcag tgtcagctgc
    15901 attatcagca aatttggtta catcgatttt agctactgtt tgatcagcaa caagattacc
    15961 atcatcatct agagcaccga ttgctgttgc ggccatactt tcaatgttga cagaaagctg
    16021 ctggctaccg ttagcaccaa tttggaatgt tagtgattta ccactatctt ctgagaaagc
    16081 accgttaagg agtttcttac cgttgaattc agtacggtca gaaataccgt tagcatttgt
    16141 gccacccccg atttcttcaa caagtgaaga tatctcgtct tggatggctt gaaggtcagt
    16201 accatcttga gtacctgtgt ttcctgcttg aacaactagc tcacggacac gttgaagaat
    16261 tgagtgagtt tcagtcaatg caccctcagc tgtttggata agagaaattc cgtcttgaga
    16321 gtttttagaa gccatttcaa gacctctgat ttgtcctctc attttttcag agatcgctag
    16381 acccgctgcg tcatctcccg cacggttgat gcgaagacca gaagaaagtt tctccatgtt
    16441 ttttgagctc gcactgttgt ttgaagacaa acggtttagt gtgttaagcg ctgcaatatt
    16501 gtggttgatt ctcatgtgaa aaatacctcc atgtgtatat gtttttgaaa tcaaagactt
    16561 ccttttcttt gatttctggc gtatcagact ccaataaagc ttctaaccta tgtagattca
    16621 gttattgctt aaggatgcct ttaagcccct taatagggtt tatctgctta atttggaaat
    16681 catcatccgc ctttcaattc atatatcgac agcaacttgt aaatgtttag gcgtttcccc
    16741 aaagaaattt tacccaaaga cgattctaaa cctattatgc cgtaaagaaa aagcttgcct
    16801 gctaagccca aggatggact tgctgacaag ctgttctctc gtaataaagt ttttaagatg
    16861 tagctgtttc tttcgctttt aagagcgatt tcatgcgtgt tttgtcacgt tcgataacag
    16921 gcttcaaata acggcctgta tatgattctt ccacttcagt gatttcctca ggcgttcctg
    16981 acgcgacaat ggttccgccc ccggctccgc cttccgggcc caaatccaca atgtaatcgg
    17041 ccgtcttaat gatatcaaga ttgtgctcaa taaccagtac agtgtctccg ttgtctacca
    17101 accgttgcag cacgacaaga agcctggcga tatcgtcgac atgcaaacct gtcgtcggct
    17161 catctaaaat gtagagcgtg cgtccggtcg agcgtttgtg cagctctgat gcgagcttca
    17221 cgcgctgcgc ttctccgcct gacaaggtcg tcgccggctg gccgagcgta atataaccta
    17281 aaccaacatc ataaagggtt tggagcttgc gtttgatttt cgggatattt tcaaagaaag
    17341 aaagagcatc ttcaaccgtc atatcaagca catcagagat gctttttcct ttgtacgtca
    17401 cttcaagcgt ttcacggtta tagcgtttgc cgtgacacac ctcgcatgga acgtatacgt
    17461 caggaaggaa gtgcatttca attttaataa tcccgtctcc gcggcaggct tcacatcgtc
    17521 cgcccttcac gttgaagctg aaacggcctt ttttatagcc gcggaccttc gcttcatttg
    17581 tctgcgcgaa tacatcacga atgtcatcaa atacaccggt gtatgtcgca gggttggatc
    17641 tcggcgttct tccgattggc gcctggtcaa tgtcaatgac tttgtctaag tgatccaaac
    17701 ctttaatctc tttatggctg ccgggcttcg ctttcgcttt atgaagcttt tgcgccagcg
    17761 ccttatgcaa aatttcatta acgagtgtac tctttcctga accggaaaca cctgtaactg
    17821 ctgtaaacgt cccaagcggg aacttggcat tcactttttt caggttgttt tctgaagcac
    17881 ctttaatttc aatgtaacgt ccgtccggct ttcttctttc aggaggcaat gggataaact
    17941 ttttccctga taaatagctg cccgttaatg agtttggatc ttccatcact tcttccggcg
    18001 tacccgcaga tatcacctgt ccgccgtgaa tgccggctcc cggtccaatg tctattaaat
    18061 aatctgctgc catcatcgtg tcctcatcat gttcgacaac aatcagcgtg ttcccgaggt
    18121 ctctcatatt tttcagtgcg ctgatcaagc ggtcgttatc acgctgatgc agaccgatag
    18181 acggctcatc taaaatataa agcacaccgg ataaacgcga gccaatttga gtcgccagcc
    18241 tgatgcgctg cgcctctcct ccggacaatg tacccgctgc cctgctcaat gtcaggtaat
    18301 cgagaccgac tttgtccaga aagcttaagc gctccacaat ttcgcgcaaa atcaaattgg
    18361 cgatctgcat atccttctca gaaagggtaa ggtctttaaa gaaggcaagt gcgtcggcga
    18421 cagacagctc ggtaattttt ccaatgtggc ggccgtcaat cagtacggca agtgcctctt
    18481 tctttaaccg atagcctttg cacgtcggac aagacttctg agacatatac tgctccattt
    18541 gctcacgtat gaaatcggag cctgtctcct tatagcgtct ttcaatgttg cgcaatacgc
    18601 cttcaaattg aatttcacct tcgcggattt gtccaaaatc attttcatat cggaaataaa
    18661 tcaggtcatc tccgctgccg tacagcactt tatccagttg atgcttcggc aaatctttga
    18721 ccggcacatc catatcaatc ccgtagtggg tgcagactgc ctcaagaagc tgaggataat
    18781 attgtgagct gatcggtgtc caaggggcga ccgcattctc cttcaatgac aaatcttgat
    18841 tgggaatgac aagatcggca tccacttcaa gcttcattcc gagaccgtca cacgtcggac
    18901 acgccccgaa cggactgtta aacgaaaaca gacgcggctc aagctcacca attgaaaatc
    18961 cgcagtgcgg acaggcatga tgctcgctga acatcagctc ttcctcaccg atgacatcga
    19021 tcataacccg tccttcacct aaacggagcg ccgtttccaa tgaatcagac agccgggctg
    19081 ccacgccttc tttcacgaca atccggtcaa tgactacctc aatggaatgc ttcttgttct
    19141 tttctaattc gatatcgtcg gaaagctcag ccatctcgcc gtcaattctg actctgacat
    19201 agccttgttt tctaatctgt tcaagcactt tgacatgagc gccttttcgg cccgagacaa
    19261 tcggcgccaa cacctgaagc ttcgtccgtt ccgggtattc cagaattctg tccaccattt
    19321 gctcgatggt ctgggatgta atctcaattc cgtgctccgg acaatgaggc ttccctactc
    19381 tcgcatataa aagacgcaga taatcataaa tctcagttac cgtaccgaca gtagacctcg
    19441 gattacggct tgttgttttc tgatcaatgc tgatggcggg agagagcccc tcaattgcat
    19501 ccacatcagg cttatccatt tgccctaaaa actggcgggc ataagcagac agcgactcga
    19561 cataccgtct ctgtccttca gcatatatcg tgtcaaaggc aagggaggat ttacctgatc
    19621 cggacaaacc cgtgacaacg acaagctgat ctctcggaat cgttacatct atatttttca
    19681 ggttatgcgc cctggctccc ttcacctcta tccgatccat agccatttgt tcatcatcct
    19741 tccgctttta gctctaaaag taaatcgcga agctccgcgg ctctttcaaa gtcaagcgcc
    19801 ttggcggctt ccttcatttc atgctccatc tgttcaacga ctttctggcg ttctttcttc
    19861 gtcattttcg acagcttcgg cgcggctttt gttttgtatt ccgctttatc ctcagctgct
    19921 actgtggcac gaatgacatc gcgaatttct ttatttatcg ttttcggcgt aatgccgtgc
    19981 tcttcattaa accgctcctg ctgctcgcgg cggcgttttg tttcattaat cgcaatttcc
    20041 atagacttcg ttattttatc ggcgtacata atgacgcggc cttccgcatt tctcgctgcc
    20101 cgtccgatgg tctggatcag cgaccgctcc gaacgaagga aaccttcctt atccgcatcc
    20161 aaaatcgcaa caagggatac ttcgggaatg tccaaacctt ccctcagcag gttgatgccg
    20221 acaagcacat cgtacttgcc aaggcgcagg tcgcggataa tttcaatccg ttcaagcgtc
    20281 ttgatctcag aatgcagata gtttacttta atgccgattt cctttaaata atcggtcaga
    20341 tcctctgaca tcttcttcgt caaagttgtc acaagcaccc gttcattccg ctctattcta
    20401 gcttgaattt cgccgatcaa gtcgtcaatc tgaccttcga ttggacggac gtcaataagc
    20461 gggtcaagaa gccccgtcgg acgaatgatc tgttcgacca tttcatctgt atgttcaatc
    20521 tcgtacggcc ctggtgttgc ggatacatac acaatattgt gcatatgctt ttcaaattcc
    20581 tcaaaacgaa gcggacggtt atcaagcgct gatggaagcc ggaagccgtg atccacgagc
    20641 acctgtttcc gcgcctggtc tccgttaaac atgccgcgca cctggggaat tgtcacatgc
    20701 gactcatcca ccacgatcat aaaatcgtct gggaaataat caagaag
//
